第二届临床心血管病大会暨第八届中国冠心病介入沙龙
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中国循证心血管医学杂志2010年12月第2卷第4期Chin J Evid Based Cardiovasc M 【rJ , , . , ‘245‘ 转血管重构。在球囊损伤小鼠颈动脉后,TNF—ot的 表达迅速上调,TNF.仅能够迅速招募白细胞到病变 部位,雌激素通过调节TNF一仪的表达来抑制早期炎 症反应。 [1] 参考文献 Tuncman G,Himsumi J,Solinas G,et a1.Functional in vivo inter- actions between JNK1 and JNK2 isoforms in obesity and insulin re- sistance.Proc Natl Acad Sci USA.2006.103:10741—10746. [2]Kunsch C,Medford RM.Oxidative stress as a regulator of gene ex— pression in the vasculature.Circ Res,1999,85:753—766. [3]Taniyama Y,Griendling KK.Reactive oxygen species in the vascn- lature:molecular and cellular mechanisms.Hypertension,2003, 42:1075—1081. 1 4 j Davidson SM,Duchen MR.Endothelial mitochondria:contributing to vascular function and disease.Circ Res,2(x】7,1oo:1 128.1】41. [5]Locatelli F,Canaud B,Eckardt KU,et a1.Oxidative stress in end. stage renal disease:an emerging threat to patient ontconle.Nephrol Dial Transplant.2003.18:l272.1280. [6]Goligorsky MS.Endothelial cell dysfunction:cant live with it.how to live without it.Am J Physiol Renal Physiol,2005,288:F871— 880. [7]Xing D,Miller A,Novak L,et a1.Estradiol and progestins differen— tially modulate leukocyte infiltration after vascular injury.Circula— tion,2004,109:234—241. [8]Miller AP,Feng W,Xing D,et a1.Estrogen modulates inflammatory mediator expression and neutrophil chemotaxis in injured arteries. Circulation,2004,l1O:l664—1669. [9 j Miller AP,Xing D,Feng W,et a1.Aged rats lose vasoprotective and anti-inflammatory effocts of estrogen in injured arteries.Meno— pause,2007,14:25l-260. [10]Oparil S,Chen SJ,Chen YF,et a1.Estrogen attenuates the adventi— tia1 contribution to neointima formation in injured rat carotid arter ies.Cardiovasc Res,1999,44:608_614. [11]Oparil S,Levine RL,Chen SJ,et a1.Sexually dimorphie response of the balloon—injured rat carotid artery to hormone treatment.Circu. 1ation,1997,95:1301.1307. [12]Sunday L,Tran MM,Krause DN.et a1.Estrogen and progestagens differentially modulate vascular proinflammatory factors.Am J Physiol,2006,291:E261-267. 『l3]Luster AD.Chemokines:chemotactic cytokines that mediate in- flammation.N Eng J Mcd,1998,338:436445. [14]Suzuki A,Mizuno K,Ino Y,et a1.Effects of l7 beta—estradiol and progesterone on growth—factor—・induced proliferation and migration in human female aortic smooth muscle cells in vitro.Cardiovasc Res, 1996,32:516-523. [15]Li G,Chen YF,Kelpke SS,et a1.Estrogen attenuates integrin—beta (3)-dependent adventitial fibmblast migration after inhibition of osteopontin production in vascular smooth muscle cells.Circula— tion.2000.10l:2949-2955. [16]Li G,Oparil S,Kelpke SS,et a1.Fibmblast growth factor receptor一1 signaling induces osteopontin expression and vascular smooth BUS- cle cell—dependent adventitial fibroblast migration in vitro.Circula- tion,2002,106:854-859. [17]“P,Oparil S,Chen YF.Hypoxia—responsive growth factors upreg— ulate periostin and osteopontin expression via distinct signaling pathways in rat pulmonary arterial smooth muscle cells.J Appl Physiol,2004,97:1550—1558. [1 8]Hayashi T,Yamada K,Esaki T,et a1.Estrogen increases endotheli. al nitric oxide by a receptor mediated system.Biochem Biophys Res Commun,1995,214:847 855. 【l9]TolbertT,Thompson JA,Bouchard P,et a1.Estrogen.induced vaso protection is independent of inducible nitric oxide synthase expres- sion:Evidence from the mouse carotid artery ligation mode1.Circu- 1ation,2001,104:2740-2745. [2(】]Straub RH.The complex role of estrogens in inflammation.Endocr Rev,2007,28:521-574. [2I]Miller VM,Duckies SP.Vascular actions of estrogens:functional implications.Pharmacol Rev,2008,60:210-241. [22]Xing D,Feng W,Miller AP,et a1.Estrogen modulates TNF—in— duced infammation in rat aortic smooth muscle cells through estro— gen receptor—p activation.Am J Physiol,2007,292:H2607一 H2612. [23]Rider V,Li X,Peterson G,et u1.Differential expression of estrogen receptors in women with systemic lupus erythematosus.J Rhenma— tol,2006,33:1093—1101. [24]Krom YD,Pires NM,Jukema JW,et a1.Inhibition of neointimafor. marion by local delivery of estrogen receptor alpha and beta specific agonists.Cardiovasc Res,2007,73:217-226. (收稿日期:2010-09-08 修回日期:2010.10-26) 第二届临床,b an管病大会暨第八届中国冠心病介入沙龙 .会讯. 由中国医疗保健国际交流促进会心血管分会主办,中华心血管病杂志、心肺血管病杂志、首都医科大学心脏病学系协办 的第二届临床心血管病大会(CCC2011)暨第八届中国冠心病介入沙龙(CISC2011)将于2011年1月13日.16日在北京九华国 际会议中心召开。 会议将继续秉承“回归临床一为广大心血管医生解决临床实际问题”的宗旨,会议内容涉及冠心病、结构性心脏病、心律失 常、高血压病、心力衰竭、血脂紊乱、糖尿病等心内科常见、多发疾病及心脏解剖、物理诊断等基础知识。“关注细节、带来问 题、带回答案,以病例为基础,解决临床诊治问题”将是本次会议的亮点。