Chapter17 Fatty Acid Oxidation by 昌增益 Compressed

• Later, enzyme digestion of proteins (much milder condition) helped to unveil which of these identified amino acids are actual building blocks of proteins.
DNA replication
Immune response (defending)
Light production (Luciferase)
O2 transport (Hemoglobin)
Support (keratin)
All proteins are constructed from the same set of 20 standard amino acids!
a
Common structure
1.
3.
The 20 amino acids are commonly categorized into five groups based on side chain features.
2. 4.
5.
Each amino acid possesses: 1. a common name 2. a three-letter abbreviation 3. an one-letter symbol
Biochemistry lecture 2 (Sept. 18, 2014)
Part I Structure and Catalysis
Chapter 3 Amino acids and Peptides
By Prof. Zengyi Chang (昌增益）
a-amino acid
Proteins are structurally and

专利名称：一种α,β-二氨基酸衍生物及其合成方法和应用专利类型：发明专利
发明人：胡文浩,荆常诚,钱宇,周静,张霞,孙照栓,杨琍苹
申请号：CN201110357971.8
申请日：20111111
公开号：CN102432485A
公开日：
20120502
专利内容由知识产权出版社提供
摘要：本发明公开了一种α，β-二氨基酸衍生物的合成方法，以重氮化合物、苯胺、醛酸酯为原料，以金属路易斯酸、手性磷酸为催化剂，以有机溶剂为溶剂，以分子筛为吸水剂，经过一步反应得到所述α，β-二氨基酸衍生物。

本发明合成方法具有高原子经济，高选择性，高收率的优势，并且反应条件温和，操作简单安全。

本发明α，β-二氨基酸衍生物具有抗癌活性和结构多样性，适用于抗肿瘤、抗生素、抗真菌药物的制备应用。

申请人：华东师范大学
地址：200062 上海市普陀区中山北路3663号
国籍：CN
代理机构：上海麦其知识产权代理事务所(普通合伙)
代理人：董红曼
更多信息请下载全文后查看。

oxidation.
Stage 2: The acetyl groups are oxidized to CO2 via the citric acid cycle.
Stage 3: Electrons derived from the oxidations of stages 1 and 2 pass to O2 via the mitochondrial respiratory chain, providing the energy for ATP synthesis by oxidative phosphorylation
2. Oxidation of Fatty acid - types: , , - oxidation - subcellular location - reaction mechanism - differences between saturated and unsaturated FA, even-chain and odd-chain FA
Fatty acid oxidation provides
metabolic energy, heat and water
增加皮下脂肪 增加内脏脂肪
Gesta et al., 2007, Cell
Contents:
1. Digestion, mobilization and transport of fats
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Chapter 17
Oxidation of Fatty Acids
(A central energy-yielding pathway in animals)
What purpose does fatty acid oxidation serve in animals ?

丙二醛氧化对大豆蛋白功能性质的影响刘晶;蔡勇建;吴伟;林亲录;华欲飞【摘要】Malondialdehyde was selected as a representative of reactive aldehydes produced in the process of polyunsaturated fatty acids lipid peroxidation catalyzed by lipoxygenase,and the effects of oxidation by malondialdehyde on functional properties of soybean protein were studied. The results indicated that car-bonyl content of soybean protein increased and the solubility decreased with malondialdehyde concentra-tion increasing;with the oxidation degree of soybean protein deepening,water holding capacity,oil holding capacity,emulsifying activity, emulsion stability, foaming capacity and foam stability of soybean protein firstly increased then decreased. When malondialdehyde concentration was 0. 1mmol/L,water holding capacity,oil holding capacity,emulsifyingactivity,emulsion stability,foaming capacity and foam stability of soybean protein reached the maximum value.%以丙二醛代表脂肪氧合酶催化多不饱和脂肪酸脂质过氧化反应过程中产生的活性醛类，研究丙二醛氧化对大豆蛋白功能性质的影响。