Rabbit Anti-CD19抗体说明书
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AMMS TM CD3/CD28抗体偶联磁珠说明书产品名称通用名称:CD3/CD28抗体偶联磁珠英文名称:Anti-human CD3/CD28 monoclonal antibody beads适用范围AMMS TM CD3/CD28磁珠适用于人T细胞的分离,激活和扩增。
适用于直肠癌、乳腺癌、肺癌、肾癌、淋巴瘤、白血病、多发性骨髓瘤、恶性黑色素瘤、卵巢癌等多种肿瘤的细胞免疫治疗临床研究。
AMMS CD3/CD28磁珠提供了一种不需要抗原呈递细胞和抗原就能激活和扩增调节T细胞的简单的方法。
通过在磁珠上组合抗CD3和抗CD28抗体,就能提供调节T细胞激活和扩增需要的初级和协同刺激信号。
使用说明一、AMMS TM CD3/CD28磁珠的清洗:1.1 在小管里重悬磁珠(也就是说,涡旋超过30s,或者颠倒混匀5min)1.2 将确定体积的磁珠转移到管子中。
1.3 加入等体积的PBS缓冲液含1%的HAS,或者至少1ml的体积,进行重悬。
1.4把管子放在一个磁铁上1min,随后弃去上清。
1.5将管子从磁铁上转移下来,用相同体积的PBS缓冲液含1%的HAS重悬磁珠(第二步最初体积的磁珠)。
二、磁珠分离和扩增CD3+的T细胞注意:由于单核细胞在37℃能够快速的吞噬磁珠,因此就降低了所能够接触到T细胞磁珠的绝对数量,进而降低了T细胞活化和扩增的能力。
2.1 通过流式或者是其他的方法确定样本中CD3+T细胞的比例。
2.2 对于Ficoll分离的PBMC,将细胞轻柔的重悬于含1%HAS的PBS缓冲液中,并调节细胞密度为2-5×107个/mL,此处注意,总的细胞数量不要超过2×108个。
2.3 将磁珠和细胞比例为3:1,加入已经洗过的AMMS TM CD3/CD28磁珠。
2.4 将样品置于1转的摇床上,在4℃-25℃条件下孵育30min,在每次的试验中需要在4℃-25℃范围内优化最适的孵育温度。
2.5用无血清培养基或者含1%HAS的PBS缓冲液稀释磁珠和细胞的混合物,来保证磁铁的分选体积。
碧云天生物技术/Beyotime Biotechnology 订货热线:400-168-3301或800-8283301 订货e-mail :****************** 技术咨询:***************** 网址:碧云天网站 微信公众号HLA-DR Rabbit Monoclonal Antibody产品编号 产品名称包装 AF2065HLA-DR Rabbit Monoclonal Antibody50µl产品简介:来源 用途交叉反应性 分子量 RabbitWB, IF, IHC, ICC, FCH, M, R29 kDaWB, Western blot; IP, Immunoprecipitation; IF, Immunofluorescence; IHC, Immunohistochemistry; ICC, Immunocytochemistry; FC, Flow Cytometry; ELISA, Enzyme-linked Immunosorbent Assay; ChIP, Chromatin Immunoprecipitation Assay.H, Human; M, Mouse; R, Rat; C, Chicken; Cw, Cow; Dg, Dog; Gp, Guinea pig; Hm, Hamster; Hr, Horse; Mk, Monkey; Pg, Pig; Rb, Rabbit; S, Sheep; Z, Zebrafish; All, all species expected.配套提供了Western 一抗稀释液,可以用于Western 检测或其它适当用途时的一抗稀释。
建议抗体使用时的稀释比例如下(实际使用时需根据抗原水平的高低作适当调整):抗体详细信息如下:About this AntibodyName HLA-DR Rabbit Monoclonal AntibodyCategory Rabbit Monoclonal Antibody (RabMAb); Primary antibody Isotype IgGPurification Affinity purification About the ImmunogenImmunogen Recombinant protein Gene ID 3122(Human) SwissProt P01903(Human) Synonyms HLA-DRA1; MLRWCategoryImmunology/InflamationBackgroundMajor histocompatibility complex (MHC) class II molecules destined for presentation to CD4+ helper T cells is determined by two key events. These events include the dissociation of class II-associated invariant chain peptides (CLIP) from an antigen binding groove in MHC II α/β dimers through the activity of MHC molecules HLA-DM and -DO, and subsequent peptide antigen binding. Accumulating in endosomal/lysosomal compartments and on the surface of B cells, HLA-DM, -DO molecules regulate the dissociation of CLIP and the subsequent binding of exogenous peptides to HLA class II molecules (HLA-DR, -DQ and -DP) by sustaining a conformation that favors peptide exchange. RFLP analysis of HLA-DM genes from rheumatoid arthritis (RA) patients suggests that certain polymorphisms are genetic factors for RA susceptibility. HLA-B belongs to the HLA class I heavy chain paralogs. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. HLA-B and -C can form heterodimers consisting of a membrane anchored heavy chain and a light chain (β-2-Microglobulin). Polymorphisms yield hundreds of HLA-B and -C alleles.包装清单:产品编号 产品名称包装 AF2065 HLA-DR Rabbit Monoclonal Antibody50µl AZ050 Western 一抗稀释液50ml —说明书1份保存条件:WBIP IFIHC ICCFCELISA ChIP 1:1,000-1:5,000 -1:50-1:2001:50-1:2001:50-1:2001:50-1:100--2 /3 AF2065 HLA-DR Rabbit Monoclonal Antibody400-1683301/800-8283301 碧云天/BeyotimeHLA-DR Rabbit Monoclonal Antibody -20ºC 保存,Western 一抗稀释液-20ºC 或4ºC 保存,一年有效。
BD Pharmingen™Technical Data SheetMouse B Lymphocyte Activation Antibody Cocktail, with IsotypeControl; PE-Cy™7 CD25, PE CD69, & FITC CD19Product InformationMaterial Number:558064Size: 100 testsReactivity:QC Testing: MouseComponent:51-9003395Mouse B Lymphocyte Activation Antibody Cocktail; PE-Cy™7 CD25, PEDescription:CD69, and FITC CD19Size: 100 tests (1 ea)Vol. per Test:20 ulStorage Buffer:Aqueous buffered solution containing BSA and ≤0.09% sodium azide.Component:51-9003396Mouse B Lymphocyte Activation Isotype Control; PE-Cy™7, PE, and FITCDescription:Size: 100 tests (1 ea)Vol. per Test:20 ulStorage Buffer:Aqueous buffered solution containing BSA and ≤0.09% sodium azide.DescriptionThe Mouse B Lymphocyte Activation Antibody Cocktail is a three-color reagent designed to identify major subsets of B lymphocytes by direct immunofluorescent staining with flow cytometric analysis. The PC61 antibody reacts with CD25, the low affinity IL-2 Receptor α chain(IL-2Rα, p55) expressed on activated T and B lymphocytes from all mouse strains tested. CD25 is also found on some developing B cells inthe bone marrow, early developing T cells in the thymus, peripheral CD4+ regulatory T (Treg) cells, and dendritic cells. The H1.2F3 antibodyreacts with CD69 (Very Early Activation antigen). Its expression is rapidly induced upon activation of lymphocytes (T, B, NK, and NK-Tcells) neutrophils, and macrophages. CD69 is also expressed on thymocytes that are undergoing positive selection. The 1D3 antibody reactswith CD19, a B lymphocyte-lineage differentiation antigen that is expressed throughout B-lymphocyte development from the pro-B cellthrough the mature B-cell stages. Terminally differentiated plasma cells do not express CD19. The three antibodies have been titrated andpre-diluted, mixed together, and formulated for optimal staining performance. The Mouse B Lymphocyte Activation Isotype Control containsequivalent concentrations of fluorochrome- and isotype-matched negative-control immunoglobulin.The use of three different fluorochromes for the labeling of the three different antibodies permits the recognition of each of the three antigenson each cell in a sample. The levels of expression of the three antigens distinguish the major subpopulations of developing and peripheral Blymphocytes. Additional fluorochrome-labeled reagents may be combined with the Mouse B Lymphocyte Activation Antibody Cocktail, andthe Mouse B Lymphocyte Activation Isotype Control, to further characterize B-cell subpopulations.Preparation and StorageThe monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with PE-Cy7 under optimum conditions, and unconjugated antibody and free PE-Cy7 were removed.The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.The antibody was conjugated with FITC under optimum conditions, and unreacted FITC was removed.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.Application NotesApplicationFlow cytometry Routinely TestedIdentification of activated B lymphocytes using Mouse B Lymphocyte Activation Antibody Cocktail, with Isotype Control. BALB/csplenocytes were activated by culture for 48 hours with anti-IgM antibody (Jackson immunoresearch) and stained with eitherMouse B Lymphocyte Activation Isotype Control (left panels) or Mouse B Lymphocyte Activation Antibody Cocktail (middlepanels). Unactivated BALB/c splenocytes were stained with Mouse B Lymphocyte Activation Antibody Cocktail (right panels) orMouse B Lymphocyte Activation Isotype Control (not shown). Scatter plots were used to select either activated lymphoblasts (leftand middle panels) or resting lymphocytes (right panels) for data analysis. The two-color contour plots display the CD19+ Blymphocytes which express the activation antigens CD25 (top of middle and right panels) and CD69 (bottom of middle and rightpanels). Flow cytometry was performed on a BD FACSCalibur™ flow cytometry system.Product Notices1.This reagent has been pre-diluted for use at the recommended Volume per Test. We typically use 1 × 10^6 cells in a 100-µl experimental sample (a test).Since applications vary, each investigator should titrate the reagent to obtain optimal results.2.3.Please refer to /pharmingen/protocols for technical protocols.4.For fluorochrome spectra and suitable instrument settings, please refer to our Fluorochrome Web Page at /colors.PE-Cy7 is a tandem fluorochrome composed of R-phycoerythrin (PE), which is excited by 488-nm light and serves as an energy donor,5.coupled to the cyanine dye Cy7, which acts as an energy acceptor and fluoresces maximally at 780 nm. PE-Cy7 tandem fluorochrome emission is collected in a detector for fluorescence wavelengths of 750 nm and higher. Although every effort is made to minimize the lot-to-lot variation in the efficiency of the fluorochrome energy transfer, differences in the residual emission from PE may be observed.Therefore, we recommend that individual compensation controls be performed for every PE-Cy7 conjugate. PE-Cy7 is optimized for use with a single argon ion laser emitting 488-nm light, and there is no significant overlap between PE-Cy7 and FITC emission spectra. When using dual-laser cytometers, which may directly excite both PE and Cy7, we recommend the use of cross-beam compensation during data acquisition or software compensation during data analysis.Please observe the following precautions: Absorption of visible light can significantly alter the energy transfer occurring in any tandem6.fluorochrome conjugate; therefore, we recommend that special precautions be taken (such as wrapping vials, tubes, or racks in aluminum foil) to prevent exposure of conjugated reagents, including cells stained with those reagents, to room illumination.Cy is a trademark of Amersham Biosciences Limited. This conjugated product is sold under license to the following patents: US Patent Nos.7.5,486,616; 5,569,587; 5,569,766; 5,627,027.8.Warning: Some APC-Cy7 and PE-Cy7 conjugates show changes in their emission spectrum with prolonged exposure to formaldehyde. If you are unable to analyze fixed samples within four hours, we recommend that you use BD™ Stabilizing Fixative (Cat. No. 338036).9.Source of all serum proteins is from USDA inspected abattoirs located in the United States.10.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water beforediscarding to avoid accumulation of potentially explosive deposits in plumbing.This product is subject to proprietary rights of Amersham Biosciences Corp. and Carnegie Mellon University and made and sold under 11.license from Amersham Biosciences Corp. This product is licensed for sale only for research. It is not licensed for any other use. If you require a commercial license to use this product and do not have one return this material, unopened to BD Biosciences, 10975 Torreyana Rd, San Diego, CA 92121 and any money paid for the material will be refunded.ReferencesBendelac A, Matzinger P, Seder RA, Paul WE, Schwartz RH. Activation events during thymic selection. J Exp Med. 1992; 175(3):731-742. (Biology)Brandle D, Muller S, Muller C, Hengartner H, Pircher H. Regulation of RAG-1 and CD69 expression in the thymus during positive and negative selection. Eur J Immunol. 1994; 24(1):145-151. (Biology)Ceredig R, Lowenthal JW, Nabholz M, MacDonald HR. Expression of interleukin-2 receptors as a differentiation marker on intrathymic stem cells. Nature. 1985; 314(6006):98-100. (Biology)Chen J, Ma A, Young F, Alt FW. IL-2 receptor alpha chain expression during early B lymphocyte differentiation. Int Immunol. 1994; 6(8):1265-1268. (Biology) Garni-Wagner BA, Witte PL, Tutt MM, et al. Natural killer cells in the thymus. Studies in mice with severe combined immune deficiency. J Immunol. 1990;144(3):796-803. (Biology)Godfrey DI, Zlotnik A. Control points in early T-cell development. Immunol Today. 1993; 14(11):547-553. (Biology)Krop I, de Fougerolles AR, Hardy RR, Allison M, Schlissel MS, Fearon DT. Self-renewal of B-1 lymphocytes is dependent on CD19. Eur J Immunol. 1996;26(1):238-242. (Biology)Krop I, Shaffer AL, Fearon DT, Schlissel MS. The signaling activity of murine CD19 is regulated during cell development. J Immunol. 1996; 157(1):48-56. (Biology) Lowenthal JW, Corthesy P, Tougne C, Lees R, MacDonald HR, Nabholz M. High and low affinity IL 2 receptors: analysis by IL 2 dissociation rate and reactivity with monoclonal anti-receptor antibody PC61. J Immunol. 1985; 135(6):3988-3994. (Biology)Lowenthal JW, Zubler RH, Nabholz M, MacDonald HR. Similarities between interleukin-2 receptor number and affinity on activated B and T lymphocytes. Nature. 1985; 315(6021):669-672. (Biology)Marzio R, Jirillo E, Ransijn A, Mauel J, Corradin SB. Expression and function of the early activation antigen CD69 in murine macrophages. J Leukoc Biol. 1997; 62(3):349-355. (Biology)Nishimura T, Kitamura H, Iwakabe K, et al. The interface between innate and acquired immunity: glycolipid antigen presentation by CD1d-expressing dendritic cells to NKT cells induces the differentiation of antigen-specific cytotoxic T lymphocytes. Int Immunol. 2000; 12(7):987-994. (Biology)Read S, Malmstrom V, Powrie F. Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation. J Exp Med. 2000; 192(2):295-302. (Biology)Rolink A, Grawunder U, Winkler TH, Karasuyama H, Melchers F. IL-2 receptor alpha chain (CD25, TAC) expression defines a crucial stage in pre-B cell development. Int Immunol. 1994; 6(8):1257-1264. (Biology)Takahashi T, Tagami T, Yamazaki S, et al. Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4. J Exp Med. 2000; 192(2):303-309. (Biology)Taniguchi T, Minami Y. The IL-2/IL-2 receptor system: a current overview. Cell. 1993; 73(1):5-8. (Biology)Yokoyama WM, Koning F, Kehn PJ, et al. Characterization of a cell surface-expressed disulfide-linked dimer involved in murine T cell activation. J Immunol. 1988; 141(2):369-376. (Biology)Yokoyama WM, Maxfield SR, Shevach EM. Very early (VEA) and very late (VLA) activation antigens have distinct functions in T lymphocyte activation. Immunol Rev. 1989; 109:153-176. (Biology)Ziegler SF, Ramsdell F, Alderson MR. The activation antigen CD69. Stem Cells. 1994; 12(5):456-465. (Biology)。
AMMS TM人源化抗人CD3/CD19双特异性抗体说明书产品名称通用名称:人源化抗人CD3/CD19双特异性抗体英文名称:Humanized anti-human CD3/CD19 bispecific antibody适用范围AMMS TM CD3/CD19 BsAb是一种双特异性T细胞连接蛋白,这种蛋白可以连接T细胞和癌细胞,令T细胞可以选择性地接近癌细胞而达到特异性杀伤的治疗效果。
AMMS TM CD3/CD19 BiMab不仅是简单地把T细胞与肿瘤细胞相结合,还通过与T细胞表面CD3受体相结合形成复合物,进一步激活T细胞信号通路,使T细胞表达CD69、CD25,上调细胞黏附分子(CD2)、短暂释放炎症因子,令T细胞活化,并促使T细胞增殖。
功能参数参考文献1、Mølhøj, M; Crommer, S; Brischwein, K; Rau, D; Sriskandarajah, M; Hoffmann, P; Kufer, P; Hofmeister,R; Baeuerle, PA (March 2007). "CD19-/CD3-bispecific antibody of the BiTE class is far superior totandem diabody with respect to redirected tumor cell lysis". Molecular Immunology 44 (8): 1935–43.doi:10.1016/j.molimm.2006.09.032. PMID 17083975.2、Amgen (30 October 2012). Background Information for the Pediatric Subcommittee of the OncologicDrugs Advisory Committee Meeting 04 December 2012 (PDF) (PDF). Food and Drug Administration.Blinatumomab (AMG 103).3、Amgen Receives FDA Breakthrough Therapy Designation For Investigational BiTE® AntibodyBlinatumomab In Acute Lymphoblastic Leukemia" (Press release). Amgen. 1 July 2014.。
【儿童用药】无儿童用药的系统试验数据,建议儿童用量参考成人剂量按体重计算。
【老年患者用药】无老年患者用药的系统试验数据,建议老年患者用量参考成人剂量按体重计算。
【药物相互作用】- 慎重联合用药:● 环孢素,他克莫司,吗替麦考酚酯:因过度免疫抑制可导致淋 巴细胞增生。
● 减毒活疫苗:可导致致命性全身性感染。
这种危险对再障患者 会更高,因其免疫功能低下。
- 兔抗人胸腺细胞免疫球蛋白能诱导可与其它兔免疫球蛋白发生反 应的抗体。
- 使用兔抗人胸腺细胞免疫球蛋白后2个月内,其兔抗体产生会干 扰ELISA检测结果。
【药物过量】超量使用兔抗人胸腺细胞免疫球蛋白(>5mg/kg/日)会导致白细胞降低和血小板降低。
延长使用时间(超过3周)会导致严重感染并增加淋巴瘤发生的危险。
【有效期】36个月【贮藏】2℃-8℃避光保存和运输,不得冰冻。
建议溶解后立即使用。
溶解后的产品在20℃的温度下,24小时内可保持稳定性。
【执行标准】进口注册标准JS20080022【批准文号】S2*******【生产企业】生产厂: Genzyme Polyclonals S.A.S.1541, Avenue Marcel Merieux, Batiments C4 et C5 69280 Marcy L’Etoile, France电话 +33 04 37 28 1600 传真: +33 04 37 28 16 79公 司: Genzyme Europe B.V.Gooimer 10, 1411 DD Naarden, Pays BasThe Netherlands电话 +31 35 699 1200 传真: +31 35 694 3214。
Anti-FLAG(DYKDDDDK)免疫磁珠Cat#:MIP0064(本品仅用于科学研究,不可用于诊断及治疗)一.背景信息Flag-Tag(DYKDDDDK),常用于真核蛋白质重组表达标记。
Anti-FLAG(DYKDDDDK)免疫磁珠,由高品质的FLAG抗体与磁珠共价偶联制成, 具有高载量(至少为0.6mg protein/ml磁珠),高特异性,操作迅速便捷,性质稳定,可反复使用的特点,可用于FLAG标签融合蛋白的亲和纯化及免疫(共)沉淀。
二.性能指标应用范围:可用于Met修饰的N端FLAG融合蛋白(Met-FLAG–Protein),N端FLAG融合蛋白(FLAG–Protein)和C端FLAG融合蛋白(Protein-FLAG)的亲和纯化及免疫(共)沉淀。
抗体属性:小鼠单克隆抗体,IgG2a亚型。
磁珠属性:琼脂糖包裹的超顺磁珠,平均粒径50um。
载量:0.5mL纳米磁珠,共价偶联2mg Anti-FLAG单克隆抗体,可纯化或沉淀至少0.6mg FLAG融合蛋白。
强度:竞争洗脱,可反复使用5次以上。
成分:0.5mL共价偶联Anti-FLAG单克隆抗体的磁珠, 溶于1ml PBS中。
保存方法:在加入了0.2‰叠氮钠的PBS保存液中,4℃可保存1年。
三.说明书阅读指南四.用前必读1.以下试剂及设备,需要客户自备,试剂推荐配方见说明书附件1, 推荐蛋白质制备方案见附件2。
磁力架1个,1.5mL 离心管若干细胞裂解液,酸性洗脱液,中和液,PBS,2x蛋白上样缓冲液, 3xFLAG多肽(货号Q7007)待测抗原样品及检测抗体2.注意事项(开箱前必读)1)本产品在在加入了0.2‰叠氮钠的PBS保存液中,4℃可保存1年,冷藏条件下运输。
2)勿离心、冷冻、干燥磁珠,勿使用超声处理磁珠,勿使酸处理磁珠时间超过10min。
3)混匀磁珠时,请采用移液枪轻柔吹打,柔和涡旋,上下颠倒及摇床混匀等方法。
勿使用超声等方法。
CD MARKER ANTIBODIESThe cluster of differentiation (abbreviated as CD) is a protocol used for the identification and investigation of cell surface molecules. So-called CD markers are routinely used for the immunophenotyping of cells. Despite this use, they are not limited to roles in the immune system and perform a variety of roles in cell differentiation, adhesion, migration, blood clotting, gamete fertilization, amino acid transport and apoptosis, among many others. As such, Proteintech’s mini catalog featuring its antibodies targeting CD markers is applicable to a wide range of research disciplines.IntroductionImmunohistochemical of paraffin-embedded human hepatocirrhosis using PECAM1, CD31 Figure 1: Immunofluorescence staining of PECAM1 (11256-1-AP), Alexa 488 goatImmunohistochemical staining of paraffin-embedded human colon tissue using NCAM1 Mouse brain tissue lysate was separated by SDS PAGE, followed by Western blot experiment Immunohistochemical of paraffin-embedded human colon using E-cadherin Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using FAS Antibody (13098-1-AP) at a dilution of 1:50 (10x objective).Immunohistochemical of paraffin-embedded human skin using E-cadherinHeLa cells were subjected to SDS PAGE followed by Western blot with CD44 antibody Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using CD44Immunohistochemical of paraffin- embedded human kidney using CD146/MCAM Immunohistochemistry of paraffin-embedded human ovary tumor tissue slide using CD146/OPTIMIZE YOUR ANTIBODY EXPERIMENTS WITH PROTEINTECHRequest your free technical guide from .THE BENCHMARK IN ANTIBODIESSince the day it was founded, Proteintech has been makingall of its products to the highest standards possible whilst takingcomplete responsibility for the quality of each product.• Proteintech makes every single antibody in its 12,000+ catalog.• Each Proteintech product is unique and cannot be bought undera different label.• Antibodies are tested with siRNA treated samples todemonstrate specificity.• It works in every single species and application or get a fullmoney-back refund.Proteintech has over 12,000 antibodies in its extensivecatalog, all fully validated and available for next day delivery.CD No.Antibody NameCat. No.TypeApplicationsCD10MME/Neprilysin 18008-1-AP Rabbit Poly ELISA, FC, IHC, IP , WB CD10MME/Neprilysin 10302-1-AP Rabbit Poly ELISA, FC, IHC, WBCD10MME/Neprilysin 23782-1-AP Rabbit Poly ELISA, FC, IHC CD10MME/Neprilysin 23898-1-AP Rabbit PolyELISA, FC, IF, WBCD10MME/Neprilysin 60034-3-Ig MouseMono ELISA, IHC, WBCD102ICAM210121-2-AP Rabbit Poly ELISA, IHC, WB CD104Integrin beta-421738-1-AP Rabbit Poly ELISA, FC, IHC, IP , WB CD105Endoglin/CD10510862-1-AP Rabbit Poly ELISA, IHC, IP , WBCD106VCAM-111444-1-AP Rabbit Poly ELISA, FC, IF, IHC, WB CD107a LAMP121997-1-AP Rabbit Poly ELISA, IF, IHC, IP , WB CD107a LAMP155273-1-AP Rabbit Poly ELISA, IF, WB CD109CD10918715-1-AP Rabbit Poly ELISA, IP , WB CD112Nectin 210100-2-AP Rabbit Poly ELISA, FC, IF, WB CD113PVRL3, Nectin 311213-1-AP Rabbit Poly ELISA, IF, IHC, IP , WB CD114 G-CSFR 18310-1-AP Rabbit Poly ELISA, FC, WB CD116CSF2RA/CD11618307-1-AP Rabbit Poly ELISA, IHC, WB CD117c-Kit/CD11718696-1-AP Rabbit Poly ELISA, FC, IF, IHC, WB CD118LIFR 22779-1-AP Rabbit Poly ELISA, FC, IHC, IP , WB CD119IFNGR110808-1-AP Rabbit Poly ELISA, FC, IHC, IP , WB CD11b CD11B/Integrin alpha M 20991-1-AP Rabbit Poly ELISA, FC, IHC, WB CD11bCD11B/Integrin alpha M21851-1-APRabbit PolyELISA, IHCCD No.Antibody NameCat. No.TypeApplicationsCD11c CD11c/Integrin alpha X 17342-1-AP Rabbit PolyELISA, FC, IHC, WBCD11c CD11c/Integrin alpha X 60258-1-Ig MouseMono ELISA, IHC, WBCD11d CD11d/Integrin alpha D 55162-1-AP Rabbit Poly ELISA, WB CD120a TNFR121574-1-AP Rabbit PolyELISA, FC, IF, IHC, WBCD120a TNFR160192-1-Ig Mouse Mono ELISA, FC, IHC, WB CD120b TNFR219272-1-AP Rabbit Poly ELISA, FC, IF, IHC, IP , WB CD121b IL1R213591-1-AP Rabbit PolyELISA, WBCD121b IL1R260262-1-Ig MouseMono ELISA, IF, WBCD122IL2RB 13602-1-AP Rabbit Poly ELISA, WB CD123IL3RA 13655-1-AP Rabbit Poly ELISA, WB CD125IL5RA 12655-1-AP Rabbit Poly ELISA, IF, IHC, WBCD126IL6R 23457-1-AP Rabbit Poly ELISA, IP , WB CD127CD127/IL7R 17626-1-AP Rabbit Poly ELISA, FC, IP , WB CD128CXCR155450-1-AP Rabbit Poly ELISA, IP , WB CD13CD1314553-1-AP Rabbit Poly ELISA, FC, IHC, WBCD132IL2RG 11409-1-APRabbit Poly ELISA, FC, WB CD133CD13318470-1-APRabbit Poly ELISA, FC, IF, IHC, WB CD133CD13318495-1-AP Rabbit Poly ELISA, IHC, WB CD133CD133-1, 2, 4, 719945-1-AP Rabbit Poly ELISA, IHC, IP , WBCD133CD133-1, 219946-1-AP Rabbit Poly ELISA, IP , WB CD134CD134/OX4020006-1-APRabbit PolyELISA, FC, WBA NTIBODY PRODUCT LIST233621117232111210CD No.Antibody NameCat. No.TypeApplicationsCD135FLT321049-1-AP Rabbit Poly ELISA, IP , WB CD136RON, MST1R 11053-1-APRabbit Poly ELISA, WB CD138CD138/ Syndecan-110593-1-APRabbit PolyCoIP ,Dot Blotting, ELISA, IF, IHC, WBCD138CD138/ Syndecan-160185-1-Ig MouseMonoELISA, WBCD138CD138/ Syndecan-160185-2-Ig MouseMono ELISA, IHC, WBCD14CD1417000-1-AP Rabbit PolyELISA, FC, IF, IHC, WBCD14CD1460253-1-Ig Mouse Mono ELISA, IF, IHC, WB CD140b PDGFRB13449-1-AP Rabbit Poly ELISA, FC, WB CD141Thrombomodulin 14318-1-AP Rabbit Poly ELISA, FC, IHC, WBCD146CD146/MCAM 17564-1-AP Rabbit PolyELISA, FC, IF, IHC, IP , WBCD146CD146/MCAM 66153-1-Ig Mouse Mono ELISA, FC, IHC, WB CD147CD14711989-1-AP Rabbit Poly ELISA, IF, IHC, IP , WB CD148PTPRJ 55123-1-AP Rabbit Poly ELISA, IHC, WB CD15FUT419497-1-AP Rabbit Poly ELISA, IF, IHC, IP , WB CD150SLAM/CD15010949-2-AP Rabbit Poly ELISA, WB CD151CD15110418-1-AP Rabbit Poly ELISA, IP , WB CD154CD15416668-1-AP Rabbit Poly ELISA, IF, IHC, IP , WB CD156b ADAM17-Specific 20259-1-AP Rabbit Poly ELISA, IHC, WB CD159a NKG2A 10935-1-AP Rabbit Poly ELISA, IHC, WB CD164CD16412083-2-AP Rabbit Poly ELISA, FC, IHC, WBCD166ALCAM 21972-1-AP Rabbit Poly ELISA, IHC, WB CD167DDR110536-1-AP Rabbit Poly ELISA, IHC, WB CD168HMMR-Specific 15820-1-AP Rabbit Poly ELISA, FC, IF, IHC, WB CD170SIGLEC513230-1-APRabbit PolyELISA, WBCD No.Antibody NameCat. No.TypeApplicationsCD172a SIRP alpha 14482-1-AP Rabbit Poly ELISA, WB CD172b SIRP BETA 111811-1-AP Rabbit Poly ELISA, IHC, WB CD172g SIRP gamma 11857-1-AP Rabbit Poly ELISA, WB CD181CXCR155450-1-AP Rabbit Poly ELISA, IP , WB CD182CXCR220634-1-AP Rabbit PolyELISA, IF, IHC, IP , WBCD183CXCR3B-specific 60065-1-Ig Mouse Mono ELISA, FC, IF, IHC, WB CD184CXCR411073-2-AP Rabbit PolyELISA, IP , WBCD184CXCR460042-1-Ig MouseMono ELISA, FC, WBCD192CCR2-specific 16153-1-AP Rabbit Poly ELISA, FC, IHC, WBCD195CCR517476-1-AP Rabbit Poly ELISA, FC, WB CD197CCR755425-1-AP Rabbit Poly ELISA, FC, IHC CD1a CD1A 17325-1-AP Rabbit PolyELISA, WBCD1a CD1A 60173-1-Ig MouseMono ELISA, WBCD2CD210299-1-AP Rabbit PolyELISA, FC, IHC, WBCD2CD260005-2-Ig MouseMonoELISA, IHC, WBCD20CD2060271-1-Ig Mouse Mono ELISA, FC, IHC, WB CD201EPCR 11391-1-AP Rabbit Poly ELISA, IHC, WB CD202b Tie219157-1-AP Rabbit Poly ELISA, IP , WB CD206CD20618704-1-AP Rabbit Poly ELISA, FC, IHC, WB CD207Langerin 11841-1-AP Rabbit Poly ELISA, WB CD208LAMP312632-1-AP Rabbit Poly ELISA, IF, IHC, IP , WB CD210a IL10RA 13356-1-AP Rabbit Poly ELISA, FC, WB CD210b IL10RB 15102-1-AP Rabbit Poly ELISA, WB CD210b IL10RB 19387-1-AP Rabbit Poly ELISA, WB CD212IL12RB113287-1-APRabbit PolyELISA, IF, IP , WB3253311421411371111128Integrin beta-4More validation images available on our website.CD133CD14CD2CD No.Antibody Name Cat. No.Type ApplicationsCD213a2IL13RA211059-1-AP RabbitPoly ELISA, IF, IHC, WBCD215IL15RA16744-1-AP RabbitPoly ELISA, IHC, WBCD22CD2266103-1-Ig MouseMono ELISA, IHC, WBCD220INSR20433-1-AP RabbitPoly ELISA, IP, WBCD221IGF1R-Specific20254-1-AP RabbitPoly ELISA, IHC, IP, WBCD222IGF2R-Specific20253-1-AP RabbitPoly ELISA, FC, IF, IHC, IP, WBCD223LAG-316616-1-AP RabbitPoly ELISA, IP, WBCD225IFITM111727-3-AP RabbitPoly ELISA, FC, IF IHC, IP, WBCD225IFITM1-Specific60074-1-Ig MouseMono ELISA, FC, IF, IHC, IP, WBCD226CD22617842-1-AP RabbitPoly ELISA, IHCCD227MUC119976-1-AP RabbitPoly ELISA, FC, IHC, IP, WBCD227MUC123614-1-AP RabbitPoly ELISA, FC, IHC, WBCD228MFI210428-1-AP RabbitPoly ELISA, WBCD23CD2318642-1-AP RabbitPoly ELISA, FC, IHC, WBCD23CD2360208-1-Ig MouseMono ELISA, IHC, WBCD23CD2360208-2-Ig MouseMono ELISA, IHC, WBCD230PrP12555-1-AP RabbitPoly ELISA, FC, IHC, IP, WBCD231TSPAN718695-1-AP RabbitPoly ELISA, IHC, IP, WBCD233band 318566-1-AP RabbitPoly ELISA, IHC, IP, WBCD234DARC55185-1-AP RabbitPoly ELISA, IHC, WBCD235a Glycophorin A15874-1-AP RabbitPoly ELISA, FC, IHC, WBCD24CD2418330-1-AP RabbitPoly ELISA, WBCD24CD2410600-1-AP RabbitPoly ELISA, IHC, WBCD244CD24416677-1-AP RabbitPoly ELISA, IHCCD247CD24712837-2-AP RabbitPoly ELISA, FC, IHC,IP, WBCD No.Antibody Name Cat. No.Type ApplicationsCD248TEM118160-1-AP RabbitPolyELISA, FC, IF,IHC, WBCD249ENPEP17655-1-AP RabbitPoly ELISA, FC, IFCD253TRAIL17235-1-AP RabbitPoly ELISA, IF, IP, WBCD254RANKL23408-1-AP RabbitPolyELISA, IHC, IP,WBCD255TNFSF1212537-1-AP RabbitPoly Not TestedCD256TNFSF1310680-1-AP RabbitPolyCoIP, ELISA, IF,WBCD257TNFSF13B11862-1-AP RabbitPoly ELISA, WBCD258TNFSF1414194-1-AP RabbitPoly Not TestedCD26DPP410940-1-AP RabbitPolyELISA, IF, IHC,WBCD261DR424063-1-AP RabbitPoly ELISA, WBCD262DR5-Specific15497-1-AP RabbitPoly ELISA, WBCD264DcR216781-1-AP RabbitPoly ELISA, IHC, WBCD267TNFRSF13B21520-1-AP RabbitPoly ELISA, WBCD27CD2711121-1-AP RabbitPoly ELISA, FC, WBCD271p75NTR55014-1-AP RabbitPolyELISA, FC, IF,IHC, IP, WBCD274PD-L1/CD27417952-1-AP RabbitPolyELISA, IF, IHC,IP, WBCD275ICOSLG14922-1-AP RabbitPoly ELISA, WBCD276CD27614453-1-AP RabbitPolyELISA, FC, IHC,WBCD278ICOS13338-1-AP RabbitPoly ELISA, WBCD279PD-1/CD27918106-1-AP RabbitPolyELISA, FC, IF,IHC, WBCD283TLR317766-1-AP RabbitPoly ELISA, FC, IHCCD284TLR419811-1-AP RabbitPoly ELISA, IHC, WBCD286TLR622240-1-AP RabbitPoly ELISA, WBCD29Integrin beta-112594-1-AP RabbitPoly ELISA, WBCD292BMPR1A12702-1-AP RabbitPoly ELISA, IF, IP, WBIL15RACD23TEM1RANKLMore validation images available on our website.22411232211821482131411121CD No.Antibody NameCat. No.TypeApplicationsCD295LEPR 20966-1-AP Rabbit Poly ELISA, FC, IF, IHC, IP , WB CD298A TP1B311142-1-AP Rabbit Poly ELISA, IHC, WB CD299CLEC4M 22003-1-AP Rabbit Poly ELISA, IHC, WB CD301CLEC10A/CD30113590-1-AP Rabbit Poly ELISA, WB CD303CLEC4C 17941-1-AP Rabbit PolyNot TestedCD304Neuropilin 160067-1-Ig Mouse Mono ELISA, IF, IHC, WB CD31CD3111265-1-AP Rabbit PolyELISA, FC, IF, IHC, IP , WBCD31CD3166065-1-Ig Mouse Mono ELISA, IF, IHC, WB CD316IGSF814387-1-AP Rabbit Poly ELISA, IP , WB CD317BST213560-1-AP Rabbit Poly ELISA, FC, IF, IHC, WB CD318CDCP112754-1-AP Rabbit Poly ELISA, FC, WB CD319SLAMF712905-1-AP Rabbit Poly ELISA, WB CD320CD32010343-1-AP Rabbit Poly ELISA, FC, IHC, WB CD322JAM212972-1-APRabbit Poly ELISA, WB CD324E-cadherin 20874-1-AP Rabbit Poly ELISA, FC, IF, IHC, IP , WB CD325N-cadherin 13769-1-AP Rabbit Poly ELISA, IF, IHC, WBCD325N-cadherin 22018-1-AP Rabbit Poly ELISA, FC, IHC, IP , WB CD326EPCAM 21050-1-AP Rabbit Poly ELISA, FC, IF, IHC, WB CD327SIGLEC613454-1-AP Rabbit Poly ELISA, IHC, WB CD328SIGLEC713939-1-AP Rabbit Poly ELISA, FC, IHC, WBCD329SIGLEC913377-1-AP Rabbit Poly ELISA, IHC, WB CD32a CD3215625-1-AP Rabbit Poly ELISA, FC, WB CD33CD3317425-1-AP Rabbit Poly ELISA, FC, IF, IHC, WB CD332FGFR213042-1-AP Rabbit Poly ELISA, IF, IHC, WBCD334FGFR411098-1-APRabbit PolyELISA, IF, IHC, WBCD No.Antibody NameCat. No.TypeApplicationsCD336CD33655118-1-AP Rabbit Poly ELISA, WB CD338BCRP/ABCG210051-1-AP Rabbit Poly ELISA, IHC, WB CD34CD3414486-1-AP Rabbit Poly ELISA, IF, IHC, WBCD340HER2/ErbB218299-1-AP Rabbit Poly ELISA, FC, IHC, IP , WB CD340HER2/ErbB251105-1-AP Rabbit Poly ELISA, IF, IHC, WB CD349Frizzled 913865-1-AP Rabbit Poly ELISA, WB CD350Frizzled 1018175-1-AP Rabbit Poly ELISA, IHC, WB CD354TREM111791-1-APRabbit Poly ELISA, FC, IF, WB CD36CD3618836-1-APRabbit Poly ELISA, FC, IF, IHC, WB CD360IL21R 10533-1-AP Rabbit Poly ELISA, FC, IHC, IP , WB CD363S1PR1/EDG155133-1-AP Rabbit Poly ELISA, IHC, IP , WBCD37CD3721044-1-AP Rabbit PolyELISA, IHC, WBCD38CD3860006-1-Ig MouseMono ELISA, IF, WBCD39CD3919229-1-AP Rabbit Poly ELISA, FC, IHC, IP , WB CD3d CD3 delta 16669-1-AP Rabbit PolyELISA, FC, IHC, IP , WBCD3d CD3 delta 60194-1-Ig MouseMono ELISA, WBCD3e CD3 epsilon 17617-1-AP Rabbit PolyELISA, FC, IF, IHC, IP , WBCD3e CD3 epsilon 60181-1-Ig Mouse Mono ELISA, FC, IHC, WB CD3g CD3 gamma 21120-1-AP Rabbit Poly ELISA, FC, IHC, IP , WB CD4CD411056-2-AP Rabbit Poly ELISA, IHC, IP , WBCD4CD419068-1-AP Rabbit Poly ELISA, IP , WB CD42a GP914564-1-AP Rabbit Poly ELISA, IHC, WB CD42b CD42b 12860-1-AP Rabbit Poly ELISA, IHC, WB CD43CD4313959-1-APRabbit Poly ELISA, IHC, WB CD44CD4415675-1-APRabbit PolyELISA, FC, IF, IHC, IP , WB1222211332312452267251118616CD31HER2/ErbB2CD38LEPR E-cadherin TREM1More validation images available on our website.CD No.Antibody NameCat. No.Type ApplicationsCD44CD4460224-1-IgMouse Mono ELISA, FC, IF, IHC, WB CD45CD4520103-1-APRabbit Poly ELISA, FC, IHC, IP , Polymer Detection Kit, WBCD46CD4612494-1-AP Rabbit Poly ELISA, FC, IHC, IP , WB CD47CD4720305-1-APRabbit PolyELISA, IHC, WBCD49c Integrin alpha-366070-1-Ig MouseMono ELISA, FC, IF, WBCD49c Integrin alpha-321992-1-APRabbit Poly ELISA, FC, IF, IP , WB CD49d Integrin alpha-419676-1-AP Rabbit Poly ELISA, IHC, WB CD49e Integrin alpha-510569-1-AP Rabbit Poly ELISA, IF, WBCD49f Integrin alpha 6X1A-Specific 20231-1-APRabbit Poly ELISA, WBCD49f Integrin alpha 6X1B-Specific 20232-1-AP Rabbit Poly ELISA, WB CD5CD517227-1-AP Rabbit Poly ELISA, IHC, IP , WBCD50ICAM317699-1-APRabbit Poly ELISA, FC, IHC, WBCD51Integrin beta-318309-1-APRabbit Poly ELISA, IHC, WB CD54ICAM-110831-1-AP Rabbit Poly ELISA, FC, IHC, IP , WB CD55ICAM-115364-1-AP Rabbit Poly ELISA, FC, IHC, IP , WB CD56NCAM1/CD5614255-1-AP Rabbit Poly ELISA, FC, IF, IHC, WB CD56Icam-116174-1-AP Rabbit PolyELISA, IF, IHC, IP , WBCD56NCAM1/CD5660238-1-Ig MouseMono ELISA, IHC, WBCD58CD5810878-1-APRabbit Poly ELISA, WB CD58Icam110020-1-AP Rabbit Poly ELISA, FC, IF, IHC, WB CD59CD5910742-1-AP Rabbit Poly ELISA, FC, IF, IHC, WB CD61Integrin beta-318309-1-AP Rabbit Poly ELISA, IHC, WBCD62E E-selectin/CD62E 20894-1-AP Rabbit Poly ELISA, FC, WBCD62P P-selectin 13304-1-AP Rabbit Poly ELISA, IHCCD66d CEACAM3-Specific 19496-1-APRabbit Poly ELISA, FC, IHCCD66e CEA 10421-1-AP Rabbit Poly ELISA, IHC CD66f PSG111809-1-AP Rabbit Poly ELISA, IF, IHC, WBCD69CD6910803-1-AP Rabbit Poly ELISA, IHC, WB CD7CD711320-1-AP Rabbit PolyELISA, IHCCD7CD760209-2-IgMouseMono ELISA, IHC, WBCD71Transferrin receptor/CD7110084-2-APRabbit PolyELISA, IF, IHC, IP , WBCD No.Antibody NameCat. No.TypeApplicationsCD72CD7213469-1-AP Rabbit Poly ELISA, WB CD73NT5E/CD7312231-1-AP Rabbit Poly ELISA, FC, IHC, WBCD75ST6GAL114355-1-AP Rabbit Poly ELISA, IHC, IP , WBCD79a CD79A 22349-1-AP Rabbit Poly ELISA, IHC, WB CD80CD8014292-1-AP Rabbit Poly ELISA, FC, WB CD81CD8118250-1-AP Rabbit Poly ELISA, FC, IHC CD82CD8210248-1-AP Rabbit Poly ELISA, IHC, WB CD84CD8412566-1-AP Rabbit Poly ELISA, WB CD85CLILRB512881-1-AP Rabbit Poly ELISA, WB CD85FLILRA518821-1-AP Rabbit Poly ELISA, FC, WB CD85G LILRA421153-1-AP Rabbit Poly ELISA, WB CD85H LILRA211461-1-AP Rabbit Poly ELISA, IHC, WB CD86CD8613395-1-AP Rabbit Poly ELISA, FC, IHC, WBCD87uPAR 10286-1-AP Rabbit Poly ELISA, FC, IF;FC, IP , WB CD88C5AR121316-1-AP Rabbit Poly ELISA, FC, IF, IHC, IP , WB CD89CD8913245-1-AP Rabbit Poly ELISA, WB CD8b CD8B 21256-1-AP Rabbit Poly ELISA, WB CD9CD920597-1-AP Rabbit PolyELISA, FC, IHC, WBCD9CD960232-1-Ig MouseMono ELISA, IHC, WBCD94CD9413332-1-APRabbit Poly ELISA, IHC, WB CD95FAS/CD9513098-1-APRabbit PolyELISA, FC, IF, IHC, IP , WBCD95FAS/CD9560196-1-Ig Mouse Mono ELISA, FC, IHC, WB CD97CD9713071-1-AP Rabbit Poly ELISA, FC, IHC, WBCD98CD9815193-1-AP Rabbit Poly ELISA, FC, IF, IHC, IP , WB CD99CD9923079-1-AP Rabbit Poly ELISA, FC, IHC, WB CDw92SLC44A114687-1-APRabbit PolyELISA, WB1111111321175221173115431322111 THE BENCHMARKIN VALIDATIONProteintech take complete responsibility for every product theymanufacture and ensure that it will work in your hands with anextensive validation process.Here’s what you can expect:• Every antibody has been extensively validated by the in-houseteam in a wide range of applications.• Antibodies now tested in siRNA knockdown todemonstrate specificity.• Original validation data available to researcher on request.• Multi-lingual technical support available online and by email.Please Note: All products featured in this product focus are for research use only.LIVE CHAT TWITTER@proteintechBLOG /news/blogYOUTUBE /ProteintechSupport Available 24 hours via Live Chat and 9-5 (CDT) via phone. Email support also available. 1 (888) 4PTGLAB(1-888-478-4522) (toll free in USA),or 1(312) 455-8498 (outside USA)1 (312) 455-8408Proteintech Group, Inc. 5400 Pearl Street, Suite 300, Rosemont, IL 60018, USA**********************PHONE FAX ADDRESS EMAIL PHONE EMAIL FAX ADDRESS EMAIL +44 (161) 8393007+44 (161) 2413103Proteintech Europe, Ltd. 4th Floor, 196 Deansgate, Manchester, M3 3WF***********************************Sales and technical support only.PHONE FAX ADDRESS EMAIL ************or 4006-900-926************Wuhan Sanying Biotechnologies D3-3, No.666 Gaoxin Avenue, Wuhan East Lake Hi-tech Development Zone Wuhan, Hubei, P .R.C******************We are ISO 9001 and ISO 13485 accredited.Proteintech Group US Head Office Proteintech Europe United Kingdom Proteintech Europe Germany Proteintech China Office CONTACT US。
Rabbit Anti-CD19
Cat.Number:DM-0079R
Quantity size:100ul Concentration:1mg/ml Buffer=0.01M TBS(pH7.4)with1%BSA,0.03% Proclin300and50%Glycerol.
Background:CD19is a transmembrane glycoprotein that is delectively expressed on the cell surface of B-lymphocytes,where it activates intracellular signaling cascades involving both Ras and phosphatidylinositol3-kinase pathways.Lymphocytes proliferate and differentiate in response to various concentrations of different antigens.The ability of the B cell to respond in a specific,yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors.This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.
Also known as:Antibody deficiency due to defect in CD19,included;AW495831;B lymphocyte antigen CD19;B lymphocyte surface antigen B4;B4;CD19;CD19antigen;CD19molecule;Cd19 protein;Differentiation Antigen CD19;Leu12;Leu12;Lymphocyte Surface Antigen;MGC109570; MGC12802;T-cell surface antigen Leu-12.
Specificity:
●Rabbit Polyclonal IgG,affinity purified by Protein A.
●Reacts with:Human,Mouse,Rat,Pig,Cow,Horse,Guinea Pig,.
●Immunogen:KLH conjugated synthetic peptide derived from human CD19(485-526aa).
●Predicted Molecular Weight:59kDa.
Storage:Shipped at4℃,Store at-20℃(Avoid repeated freeze/thaw cycles). Application:ELISA=1:500-1000IHC-P=1:400-800IHC-F=1:400-800Flow-Cyt=1μg/Test IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note:This product as supplied is intended for research use only,not for use in human, therapeutic or diagnostic applications.
上海笃玛生物科技有限公司。