2型糖尿病合并非酒精性脂肪肝患者危险因素分析
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论 著2型糖尿病病人非酒精性脂肪肝的相关因素临床分析王吉凌, 宁 涛, 吴铁华(包头市中心医院消化科,内蒙古包头014040) 摘 要:目的:观察2型糖尿病非酒精性脂肪肝与BM I、HbA1C、TG的相关性。
方法:选取80例2型糖尿病病人合并非酒精性、药物性、自身免疫性肝炎导致脂肪肝者。
无脂肪肝的2型糖尿病50例做对照。
结果:发现BM I、Hb A1C、TG是脂肪肝形成的主要危险因素,脂肪肝组代谢综合征、高血压、冠心病的发生率明显高于对照组。
结论:2型糖尿病非酒精性脂肪肝以I R为基础的代谢综合征各相关成分之间的关系密切。
2型糖尿病积极控制体重,改善I R和控制血糖、调整血脂紊乱,对于防治非酒精性脂肪肝有重要意义。
关键词:2型糖尿病;脂肪肝;代谢综合征中图分类号:R575.5文献标识码:A文章编号:1004-2113(2007)06-0475-03CL INI CA L ANA LY SI S O N RELAT IVE FAC TO RS O F T2MD PAT I ENT W ITHO UT ALCO H OL I C FATTY L IVERWA N G J i-ling, N I NG Tao, WU Tie-hua(D epa rt m ent of Gastro enterology,Cent er H ospit a l of Baotou,Baotou014040China)Abstrac t:O b ject ive:T o observe the relationshi p bet ween T2MD w ithout alcoholic fatty liver and B M I,Hb A1C,TG.M ethods:Choosing80patients of T2MD c omp lica ted alcoholic,medical or aut oi mm une hepatilis leading to pa r ed w ith50patients of T2MD without a lcoholic fa tty liver.Results:BM I,HbA1C,TG are m ain dange r ous f actors that lead to fatty liver.The morbidity of the fatty liver gr oup that suffer fr om m etabolic syndro m e.Hypertenti on and c or onary athe r oscle r otic heart disea se is obviously highe r than that of compared gr oup.C onc lusi on:I t’sosculation connection bet ween T2MD without fatty liver and eve r y rela tive ele m ent of m etabolic syndr om e based on I R.To take precautions against unalcoholic fatty liver,it is i m portant to c ontr ol weight,i mpr ove I R,adjust blood sugar and regulate the tur bulence of bl ood li p ids actively f or the patients of T2MD.Key wor ds:diabete sm ellitus;Type2T2MD;fatty liver;m etabolic syndr om e 最近研究发现,胰岛素抵抗(I R)在非酒精性脂肪肝形成过程中起重要作用。