Neuronal communication
神经胶质细胞
按形态分类:星型胶质细胞、 少突胶质细胞 、
小胶质细胞 和室管膜细胞
胶质细胞功能:
1)支持营养和绝缘,维持神经组织内环境的稳定
2)在CNS发育过程中引导神经元走向的作用,
3)灭火神经递质的作用
脑疾病: PD 、 HD Stroke 、 精神分裂症
Brain dopaminergic pathways
1. Nigrostriatal pathway
(黑质纹状体通路) 2. Mesolimic pathway
(中脑边缘通路)
1
3. Mesocortical pathway
(中脑皮层通路)
4. Tuberohypophyseal
Mesocortical pathway 3 Tuberohypophyseal pathway 4
2
Glutamate receptors
Functions of Glutamatergic neurons
Glutamatergic neurons and NMDA receptors in the hippocampus are important in the creation of longterm potentiation (LTP), a crucial component in the formation of memory.
Noradrenergic functions
It is suggested that NA play an important role in arousal and the reward system. Depression results from a functional deficiency of NA in certain parts of the brain, while mania results from an excess. However, this has been challenged by findings which suggests a more prominent role to serotonin (5-HT) in relation to mood.