不同剂量右美托咪定复合不同浓度罗哌卡因单次股神经阻滞用于膝关
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右美托咪定复合罗哌卡因股神经阻滞在膝下型骨折手术麻醉中的应用研究【摘要】目的:研究右美托咪定复合罗哌卡因股神经阻滞在膝下型骨折手术麻醉中的应用。
方法:以2021.01~2021.12期间我院收治的84例实施膝盖骨折手术治疗的患者,随机分成罗哌卡因单一组(42例)、联合右美托咪定组(42例),罗哌卡因单一组在超声引导下,以20mL的 0.5%罗哌卡因阻滞股神经。
联合右美托咪定组在超声引导下,以20mL 的0.4%罗哌卡因阻滞股神经。
统计神经阻滞起效时间和持续时间。
结果:联合右美托咪定组的感觉和运动神经阻滞,起效时间、运动神经阻滞持续时间短于罗哌卡因单一组,感觉神经阻滞持续时间长于罗哌卡因单一组,(P<0.05)。
结论:膝下型骨折手术麻醉当中,罗哌卡因股神经阻滞复合右美托咪定,可提升麻醉效果。
【关键词】右美托咪定;复合;罗哌卡因;股神经阻滞;膝下型;骨折手术;麻醉;应用研究Application of dexmedetomidine combined with ropivacaine femoral nerve block in anesthesia for subknee fracture surgeryLiu WeiHeilongjiang Daqing Longnan hospital (the Second Affiliated Hospital of Qiqihar Medical College), Heilongjiang Daqing 1634353[Abstract] Objective: To study the application of dexmedetomidine combined with ropivacaine femoral nerve block in the anesthesia of subknee fracture surgery.Methods: 84 patients with knee fracture treated in our hospital from January 2021 to December 2021 wererandomly pided into ropivacaine single group (42 cases) and dexmedetomidine combined group (42 cases). Under the guidance of ultrasound, the femoral nerve was blocked with 20ml 0.5% ropivacaine in the ropivacaine single group. In the combined dexmedetomidine group, 20 ml of 0.4% ropivacaine was used to block the femoral nerve under the guidance of ultrasound. The onset time and duration of nerve block were counted. Results: the onset time and duration of sensory and motor nerve block in the combined dexmedetomidine group were shorter than those in the single ropivacaine group, and the duration of sensory nerve block was longer than that in the single ropivacaine group (P<0.05). Conclusion: Ropivacaine femoral nerve block combined with dexmedetomidine can improve the anesthetic effect in the operation of subknee fracture.[Key words] dexmedetomidine; reunite with; Ropivacaine; Femoral nerve block; Subgenual type; Fracture surgery; Anesthesia; application research对于膝盖骨折手术患者而言,在手术时需要根据患者身体情况对麻醉方式进行选择[1]。
右美托咪定复合罗哌卡因股神经阻滞对膝关节置换术患者术后应激的影响高俊伟【摘要】目的探究右美托咪定复合罗哌卡因股神经阻滞对膝关节置换术患者术后应激的影响.方法选择郑州市骨科医院68例择期行膝关节置换术患者,随机分组,各34例.在麻醉诱导前,观察组在股神经定位之后注射右美托咪定复合罗哌卡因实施股神经阻滞,对照组仅注射罗哌卡因行股神经阻滞.统计两组进入手术室后(T0)、手术开始即刻(T1)、术毕(T2)时应激指标[去甲肾上腺素(NE)、肾上腺素(E)]水平.结果观察组T1、T2时NE、E水平较对照组降低,差异有统计学意义(P<0.05).结论在膝关节置换术术中应用右美托咪定复合罗哌卡因股神经阻滞,可明显降低患者手术应激反应.【期刊名称】《河南医学研究》【年(卷),期】2017(026)008【总页数】2页(P1414-1415)【关键词】膝关节置换术;右美托咪定;罗哌卡因;股神经阻滞;应激反应【作者】高俊伟【作者单位】郑州市骨科医院麻醉科河南郑州 4500052【正文语种】中文【中图分类】R614.4膝关节置换术为临床矫治骨折的常用术式之一,可有效纠正患者髋关节畸形,提高日常生活能力。
但该手术创伤较大,患者常伴随剧烈疼痛,镇痛不完善可导致严重应激反应,引发血液高凝状态,造成静脉血栓[1]。
股神经阻滞可通过神经刺激仪、超声精确定位阻滞区域,具有针对性较强、副作用小、起效迅速等优势,被广泛应用于各种骨科手术中[2]。
本研究选择68例择期行膝关节置换术的患者,分组对比观察右美托咪定复合罗哌卡因股神经阻滞对膝关节置换术患者术后应激的影响。
1.1 一般资料选择2014年7月至2016年9月郑州市骨科医院68例择期行膝关节置换术的患者,随机分组,各34例。
所有患者均为择期手术患者,无股神经阻滞禁忌证,签署知情同意书,排除精神、认知障碍及对研究药物过敏者。
观察组男18例,女16例,年龄41~78岁,平均年龄(62.72±7.41)岁;对照组男19例,女15例,年龄42~76岁,平均年龄(61.94±9.58)岁。
不同浓度右美托咪定联合罗哌卡因对膝关节镜术后镇痛效果的影响董跃福;刘旭东;冯继英;张小宝;赵志斌;雷玲;徐德明;崔吉正【期刊名称】《中国现代医学杂志》【年(卷),期】2017(027)030【摘要】目的观察关节腔内注射不同浓度右美托咪定复合罗哌卡因对膝关节镜术后镇痛的效果.方法选取80例择期行膝关节镜手术患者随机分为A组(0.25%罗哌卡因+0.25μg/kg右美托咪定);B组(0.25%罗哌卡因+0.50μg/kg右美托咪定);C 组(0.25%罗哌卡因+0.75μg/kg右美托咪定);D组(0.25%罗哌卡因+1.00μg/kg右美托咪定).记录患者术中心率、平均动脉压等生命体征,术后24 h内的疼痛评分(VAS)、术后首次需要镇痛药时间、芬太尼用量及不良反应.结果 4组患者术中生命体征变化差异无统计学意义(P<0.05);术后<6h C和D组患者VAS评分低于A、B组,B组低于A组;C和D组比较差异无统计学意义(P>0.05),其他4组时间差异无统计学意义;术后首次需要镇痛药时间C、D组长于A、B组,B组长于A组,C和D组比较差异无统计学意义;术后<24 h芬太尼用量C、D组低于A、B组,B组低于A组,C和D组比较差异无统计学意义.A和B组未出现不良反应,C组出现低血压1例、恶心呕吐1例;D组出现心动过缓1例、恶心呕吐1例.结论关节腔内注射不同浓度右美托咪定复合罗哌卡因用于膝关节镜术后镇痛,其镇痛效果及不良反应呈浓度依赖性,综合考虑推荐其镇痛浓度为0.50μg/kg.%Obj ective To assess the effect of intra-articular administration of Ropivacaine combined with Dexmedetomidine on postoperative analgesia after arthoscopic knee surgery.Methods A total of 80 patients receiving arthroscopic knee surgerywere included in this study and were randomly assigned into 4groups.Patients in group A received intra-articularly 0.25% Ropivacaine plus 0.25 μg/kg Dexmedetomidine;patients in group B received 0.25%ropivacaine plus 0.50 μg/kg Dexmedetomidine;patients in group C received 0.25%Ropivacaine plus 0.75 μg/kg Dexmedetomidine;patients in the group D received 0.25%ropivacaine plus 1.00 μg/kg Dexmedetomidine.Haemodynamic changes,visual analogue scale (VAS),time of duration for the first request of analgesia postoperatively,total fentanyl consumption,and adverse effects were recorded.Results No significant difference among groups were observed in terms of haemodynamic changes during the operation (P> 0.05).The VAS scores at 6 hour post-operation in group C and D were significantly decreased when compared with group A and B (P < 0.05).The VAS scores at the 6th hour post-operation in group B were significantly decreased when compared with group A (P< 0.05).No significant difference was observed between group C and D.Time of duration for the first request of analgesia postoperatively in group C and group D were dramatically prolonged when compared with group A and group B (P < 0.05).Time of duration for the first request of analgesia postoperatively in group B was dramatically prolonged when compared with group A (P < 0.05).No significant difference was observed between group C and D.Postoperative consumption of fentanyl was decreased significantly in group C and group D when compared with group A and B.Postoperative consumption of fentanyl was decreased significantly in group B when compared withgroup A.No significant difference in fentanyl consumption was observed between group C and D.In aspect of adverse advents,one patient experienced hypotension and one patient developed nausea and vomiting in both group C and group D.No adverse effect was observed in group A and B.Conclusions Intra-articular injection of Dexmedetomidine and ropivacaine for postoperative analgesia after arthroscopic knee surgery exerts desirable analgesia while unnecessary dose of Dexmedetomidine causes side effects.Thus,the recommended analgesic dose of Dexmedetomidine is 0.50 μg/kg in addition to Ropivacaine.【总页数】6页(P64-69)【作者】董跃福;刘旭东;冯继英;张小宝;赵志斌;雷玲;徐德明;崔吉正【作者单位】江苏省连云港市第一人民医院(徐州医科大学附属连云港医院)关节外科,江苏连云港222002;江苏省连云港市第一人民医院(徐州医科大学附属连云港医院)关节外科,江苏连云港222002;江苏省连云港市第一人民医院(徐州医科大学附属连云港医院)麻醉科,江苏连云港222002;江苏省连云港市第一人民医院(徐州医科大学附属连云港医院)麻醉科,江苏连云港222002;江苏省连云港市第一人民医院(徐州医科大学附属连云港医院)麻醉科,江苏连云港222002;江苏省连云港市第一人民医院(徐州医科大学附属连云港医院)麻醉科,江苏连云港222002;江苏省连云港市第一人民医院(徐州医科大学附属连云港医院)麻醉科,江苏连云港222002;江苏省连云港市第一人民医院(徐州医科大学附属连云港医院)疼痛科,江苏连云港222002【正文语种】中文【中图分类】R614.24【相关文献】1.右美托咪定对罗哌卡因关节腔注射用于膝关节镜术后镇痛效果的影响 [J], 王春光;丁彦玲;贾军;张浩军;李永旺;马永利;韩爱萍;张励才2.关节腔内注射不同浓度右美托咪定复合罗哌卡因对老年骨科患者膝关节镜术后镇痛效果 [J], 潘春英;许旭东;张爱萍;郦惠芳;霍燕华;瞿玉兴3.不同浓度右美托咪定联合罗哌卡因对膝关节镜术后镇痛效果影响 [J], 王晓军;赵涛;胡芸;夏瑞娜;黄建成4.不同浓度罗哌卡因肋间神经阻滞联合PCIA对胸腔镜手术患者术后镇痛效果的影响分析 [J], 周晶; 崔金花; 张乙; 隋成5.超声引导右美托咪定联合罗哌卡因胸椎旁神经阻滞对开胸手术患者的麻醉及术后镇痛效果的影响分析 [J], 陈华永;马丹丹;张华朋;李鹏;赵晓东因版权原因,仅展示原文概要,查看原文内容请购买。
右美托咪定联合罗哌卡因连续股神经阻滞用于全膝关节置换术的镇痛效果分析杨旭刚;冯昌盛【摘要】目的观察右美托咪定联合罗哌卡因连续股神经阻滞在全膝关节置换术(TKA)后的镇痛效果与安全性.方法将110例TKA术后患者分为对照组(0.2%罗哌卡因术后镇痛)和观察组(1 μg/mL右美托咪定加0.2%罗哌卡因术后镇痛),均在B超引导下连续股神经置管阻滞术后镇痛.记录术后VAS、Ramsay评分,进行安全性、镇痛及功能康复评价.结果术后6、12、24 h观察组在静息态和运动态VAS评分均低于对照组(P<0.05),Ramsay评分高于对照组(P<0.05);观察组患者术侧主动直腿抬高时间、膝关节主动屈膝达90°时间均少于对照组(P<0.05);观察组镇痛满意度、功能康复满意度均高于对照组(P<0.05);术后3个月两组患者KSS各维度评分均较术前明显提高(P<0.01),术后3个月两组患者KSS各维度评分比较,差异均无统计学意义.结论右美托咪定联合罗哌卡因对TKA术后行连续股神经阻滞镇痛,能较好控制早期静息和活动痛,有利于早期功能锻炼开展,具有较好的有效性和安全性.【期刊名称】《重庆医学》【年(卷),期】2018(047)022【总页数】3页(P2978-2980)【关键词】全膝关节置换术;右美托咪定;连续股神经阻滞;术后镇痛【作者】杨旭刚;冯昌盛【作者单位】四川省南充市第五人民医院麻醉科 637000;川北医学院附属医院麻醉科,四川南充637000【正文语种】中文【中图分类】R614很多膝关节骨关节炎(knee osteoarthritis,KOA)患者因疼痛而最终决定选择行全膝关节置换术(total knee arthroplasty,TKA)治疗,且随着微创技术的发展,TKA 成为临床重要的诊治手段。
但TKA为疼痛最为剧烈的骨科手术之一,术后重度疼痛患者达60%,中度疼痛患者达30%,疼痛不仅给患者的生理、心理带来负面影响,也影响术后早期功能性恢复锻炼,降低了TKA手术疗效。
右美托咪定复合罗哌卡因及吗啡关节腔周围注射对前交叉韧带重建术后镇痛效果观察李伟;林成新;郑若芳;刘洁【期刊名称】《世界中医药》【年(卷),期】2016(0)B03【摘要】目的观察右美托咪定复合罗哌卡因及吗啡应用于关节腔周围注射对前交叉韧带重建术术后镇痛效果及其安全性。
方法:全麻下行前交叉韧带重建术患者60例,按双盲法随机分为三组,每组20例。
M组注射盐酸罗哌卡因+吗啡,D组注射盐酸罗哌卡因+右美托咪定,DM组注射盐酸罗哌卡因十吗啡+右美托咪定。
镇痛药物由手术医师在手术结束皮肤缝合前向关节腔周围滑膜组织、取腱处及各个切口周围各注射。
结果:D组、M组和DM组用药总量分别为1200、1000 mg和600 mg,用药总量对比无统计学差异。
使用镇痛药人数在7-12 h时间段DM组明显少于D组、M组(P〈0.05),在D组和M组问两组额外使用镇痛药人数没有统计学差异。
3组无术后并发症。
结论:右美托咪定和罗哌卡因关节腔周围注射与吗啡和罗哌卡因关节腔周围注射用于前交叉韧带重建术后镇痛效果相似。
关节腔周围注射右美托咪定复合罗哌卡因及吗啡用于前交叉韧带重建术后镇痛效果更佳。
【总页数】2页(P1449-1450)【关键词】前交叉韧带重建;关节腔周围注射;右美托咪定;罗哌卡因;吗啡【作者】李伟;林成新;郑若芳;刘洁【作者单位】广西医科大学第一附属医院,广西南宁530021【正文语种】中文【中图分类】R614【相关文献】1.不同剂量右美托咪定复合罗哌卡因关节腔注射对膝关节镜术后镇痛的影响 [J], 张秀丽;冯继英;崔吉正;张小宝;赵志斌;霍雯2.不同剂量右美托咪定复合罗哌卡因关节腔注射对膝关节镜术后镇痛的影响 [J], 张秀丽;冯继英;崔吉正;张小宝;赵志斌;霍雯;3.关节腔注射罗哌卡因复合右美托咪定或吗啡用于膝关节镜术后镇痛效果比较 [J], 刘清仁;肖英;张学伟;张云慧;季永4.关节腔内注射不同浓度右美托咪定复合罗哌卡因对老年骨科患者膝关节镜术后镇痛效果 [J], 潘春英;许旭东;张爱萍;郦惠芳;霍燕华;瞿玉兴5.关节腔注射右美托咪定混合罗哌卡因预防性镇痛用于膝关节镜手术后镇痛效果观察 [J], 薛金配;吕有文;解成兰;费菲因版权原因,仅展示原文概要,查看原文内容请购买。
DOI:10.19368/ki.2096-1782.2023.24.082右美托咪定复合罗哌卡因用于连续股神经阻滞在全膝关节置换术后镇痛效果的观察朱怀礼,余艾华,汪亚丹阳市人民医院麻醉科,江苏丹阳212300[摘要]目的探讨在全膝关节置换术后镇痛中采用右美托咪定复合罗哌卡因用于连续股神经阻滞的效果。
方法选择2021年1月—2022年12月于丹阳市人民医院行全膝关节置换术治疗的90例患者为研究对象,按随机数表法分组,对照组予罗哌卡因、观察组再加右美托咪定,每组45例。
比较两组术后各时间静息与被动活动疼痛程度、术后恢复情况、麻醉不良反应。
结果观察组术后4、8、12、24 h时静息疼痛评分各为(1.25±0.25)、(1.47±0.23)、(2.25±0.36)、(3.03±0.44)分,低于对照组,差异有统计学意义(t=10.561、13.775、9.004、11.029,P均<0.05);而术后36、48 h时静息疼痛评分与对照组比,差异无统计意义(P均>0.05)。
观察组患者在术后4、8、12、24、36、48 h被动活动疼痛评分均低于对照组,差异有统计学意义(P均<0.05)。
观察组术后自控泵有效按压次数少于对照组,术后下床活动时间、主动直腿抬高时间以及屈膝90°时间短于对照组,差异有统计学意义(P均<0.05)。
观察组麻醉不良反应率低于对照组,差异有统计学意义(P<0.05)。
结论在全膝关节置换术后镇痛连续股神经阻滞中联合运用右美托咪定、罗哌卡因的效果显著,能明显控制患者术后静息与活动疼痛,并有助于患者术后肢体功能的恢复,且麻醉不良反应较少。
[关键词]右美托咪定;罗哌卡因;连续股神经阻滞;全膝关节置换术;术后镇痛[中图分类号]R614 [文献标识码]A [文章编号]2096-1782(2023)12(b)-0082-04Observation on the Analgesic Effect of Dexmedetomidine Combined with Ropivacaine for Continuous Femoral Nerve Block after Total Knee Arthro⁃plastyZHU Huaili, YU Aihua, WANG YaDepartment of Anesthesiology, Danyang People's Hospital, Danyang, Jiangsu Province, 212300 China[Abstract] Objective To investigate the effect of dexmedetomidine combined with ropivacaine for continuous femoral nerve block in postoperative analgesia after total knee arthroplasty. Methods 90 patients who underwent total knee ar⁃throplasty treatment in Danyang People's Hospital from January 2021 to December 2022 were selected as the study objects and grouped according to the randomized number table method. The control group was given ropivacaine, the observation group then added dexmedetomidine, n=45. The two groups were compared with each postoperative time of resting and passive activity pain level, postoperative recovery, and anesthesia adverse reaction. Results The resting pain scores of the observation group were (1.25±0.25), (1.47±0.23), (2.25±0.36), and (3.03±0.44) points at 4, 8, 12, and 24 h postoperatively, which were lower than those of the control group, the differences were statistically significant (t=10.561, 13.775, 9.004, 11.029, all P<0.05), respectively. And there were no statistical significances in the resting pain score at 36 and 48 h postoperatively compared with the control group (both P>0.05). The passive activity pain scores of the observation group were lower than those of the control group at 4, 8, 12, 24, 36 and 48 h after operation, the differences were statistically significant (all P<0.05). In the observation group, the number of effective postopera⁃tive presses of the self-control pump was less than that of the control group, and the postoperative time of getting out of bed, the time of active straight-leg raising, and the time of bending the knee at 90°were shorter than those of the control group, the differences were statistically significant (all P<0.05). The rate of adverse reactions to anesthesia in[作者简介] 朱怀礼(1982-),男,本科,主治医师,研究方向为临床麻醉。
右美托咪定复合罗哌卡因股神经阻滞、股外侧皮神经阻滞在膝关节置换术中的效果作者:李凯刘清来源:《中国医学创新》2024年第17期【摘要】目的:探讨右美托咪定复合罗哌卡因股神经阻滞、股外侧皮神经阻滞在膝关节置换术中的效果。
方法:选取2020年6月—2023年6月萍乡市中医院收治的82例拟行膝关节置换术的患者,按照随机数字表法分为观察组和常规组,各41例。
观察组采用右美托咪定+罗哌卡因实施股神经阻滞、股外侧皮神经阻滞,常规组采用罗哌卡因股神经阻滞、股外侧皮神经阻滞。
对比两组患者手术相关指标、血流动力学、视觉模拟评分法(VAS)评分、不良反应。
结果:两组HR时间、組间、交互差异均有统计学意义(F时间=9.654,P时间=0.000,F组间=8.975,P组间=0.000,F交互=9.041,P交互=0.000);两组MAP时间、组间、交互差异均有统计学意义(F时间=10.231,P时间=0.000,F组间=8.231,P组间=0.000,F交互=8.635,P交互=0.000);观察组安装假体时(T2)及拔除气管导管5 min(T3)的HR、MAP均低于常规组(P<0.05)。
两组VAS评分时间、组间、交互差异均有统计学意义(F时间=9.432,P时间=0.000,F组间=9.342,P组间=0.000,F交互=8.321,P交互=0.000);观察组术后3、9、12、24 h的VAS评分均低于常规组,差异均有统计学意义(P<0.05)。
两组不良反应发生率比较,差异无统计学意义(字2=0.105,P=0.746)。
结论:右美托咪定复合罗哌卡因股神经阻滞、股外侧皮神经阻滞在膝关节置换术中可稳定血流动力学指标,镇痛效果显著,降低应激反应,且安全性良好。
【关键词】膝关节置换术右美托咪定罗哌卡因股神经阻滞股外侧皮神经阻滞视觉模拟评分法Effect of Dexmedetomidine Combined with Ropivacaine Femoral Nerve Block and Lateral Femoral Cutaneous Nerve Block in Knee Joint Replacement/LI Kai, LIU Qing. //Medical Innovation of China, 2024, 21(17): 161-165[Abstract] Objective: To investigate the effect of Dexmedetomidine combined with Ropivacaine femoral nerve block and lateral femoral cutaneous nerve block in knee joint replacement. Method: A total of 82 patients intending to undergo knee arthroplasty admitted to Pingxiang Hospital of Traditional Chinese Medicine from June 2020 to June 2023 were selected and divided into observation group and routine group according to random number table method, with 41 cases in each group. The observation group received femoral nerve block and lateral femoral cutaneous nerve block with Dexmedetomidine and Ropivacaine, while the conventional group received Ropivacaine femoral nerve block and lateral femoral cutaneous nerve block. Operation-related indexes,hemodynamics, visual analogue scale (VAS) score and adverse reactions were compared between the two groups. Result: There were statistically significant differences in HR time, inter-group and interaction between the two groups (Ftime=9.654, Ptime=0.000, Fgroup=8.975,Pgroup=0.000, Finteraction=9.041, Pinteraction=0.000); the differences in MAP time, inter-group and interaction between the two groups were statistically significant (Ftime=10.231,Ptime=0.000, Fgroup=8.231, Pgroup=0.000, Finteraction=8.635, Pinteraction=0.000); HR and MAP of the observation group during prosthetic installation (T2) and tracheal catheter removal5 min (T3) were lower than those of the conventional group (P<0.05). There were significant differences in VAS score time, inter-group and interaction between the two groups(Ftime=9.432, Ptime=0.000, Fgroup=9.342, Pgroup=0.000, Finteraction=8.321,Pinteraction=0.000). The VAS scores of the observation group at 3, 9, 12 and 24 h after surgery were lower than those of the conventional group, the differences were statistically significant(P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (字2=0.105, P=0.746). Conclusion: Dexmedetomidine combined with Ropivacaine femoral nerve block and lateral femoral cutaneous nerve block can stabilize hemodynamic indexes in knee joint replacement, have significant analgesic effect, reduce stress response, and have good safety.[Key words] Knee joint replacement Dexmedetomidine Ropivacaine Femoral nerve block Lateral femoral cutaneous nerve block Visual analogue scaleFirst-author's address: Department of Anesthesiology, Pingxiang Hospital of Traditional Chinese Medicine, Pingxiang 337000, Chinadoi:10.3969/j.issn.1674-4985.2024.17.037膝关节置换术手术通常包括切除受损的膝关节软骨,并替换为人工关节,以减轻疼痛和恢复关节功能[1-2]。
右美托咪定复合罗哌卡因股神经阻滞用于单侧膝关节镜术后镇痛的效果观察发表时间:2018-03-21T13:12:23.110Z 来源:《医药前沿》2017年12月第36期作者:许京亚陆香红[导读] 评估右美托咪定复合罗哌卡因行股神经阻滞用于膝关节镜术后镇痛的临床效果。
(苏州大学附属第一医院麻醉手术科江苏苏州 215006)【摘要】目的:评估右美托咪定复合罗哌卡因行股神经阻滞用于膝关节镜术后镇痛的临床效果。
方法:择期行单侧膝关节镜手术的患者60例,随机分配至1ug/kg右美托咪定复合0.15%罗哌卡因行股神经阻滞组(A组)及单纯用0.15%罗哌卡因行股神经阻滞组(B组),每组30例。
两组患者均在喉罩全麻下完成手术,术毕拔除喉罩后行超声引导下股神经阻滞用于术后镇痛。
记录两组患者行股神经阻滞之前(0h)及股神经阻滞后1h、2h、4h、6h、8h、12h、18h、24h的NRS疼痛评分、术后地佐辛的使用情况及不良反应的发生。
结果:A组患者在行股神经阻滞后2h、4h、6h、8h的NRS评分为1.7±1.0、2.0±1.1、2.1±0.8、3.4±0.6,显著低于B组(P<0.05)。
此外,A组术后24小时地佐辛的用量为(3.4±0.6)mg,明显少于B组(P<0.05)。
两组患者均无严重不良反应发生。
结论:右美托咪定混合罗哌卡因行股神经阻滞能明显加强单侧膝关节镜手术患者术后镇痛效果,减少静脉镇痛药的使用,具有显著的临床应用价值。
【关键词】膝关节镜手术;股神经阻滞;右美托咪定;罗哌卡因【中图分类号】R614 【文献标识码】A 【文章编号】2095-1752(2017)36-0219-03 膝关节镜检查是用于诊断和治疗各种膝关节内部结构疾病的常用的微创手术。
然而其可以导致不同程度的术后疼痛[1],充分的术后镇痛是减少并发症、提高患者整体满意度的关键因素。