黄斑囊样水肿的治疗方法

Tenon囊下注射曲安奈德治疗黄斑水肿的临床观察发表时间：2016-10-31T15:41:04.180Z 来源：《中国医院药学杂志》2016年9月作者：郭卫红李晓英[导读] Tenon囊下注射曲安奈德治疗黄斑水肿有较好的疗效。

中铁十七局集团有限公司中心医院山西太原邮编 030032 通讯作者：郭卫红，女 1974年10月硕士副主任医师【摘要】目的观察Tenon囊下注射曲安奈德对黄斑水肿的治疗效果。

方法对38例黄斑水肿患者给予Tenon囊下注射曲安奈德40mg,对治疗前与治疗后4、6个月的视力、眼压、黄斑区厚度进行观察比较，统计分析。

结果治疗后4个月及6个月的视力较治疗前提高，差异有统计学意义。

黄斑区厚度治疗后较治疗前变薄有统计学差异。

眼压值治疗前与治疗后有显著性差异，但无急性青光眼发作病例。

结论 Tenon囊下注射曲安奈德治疗黄斑水肿有较好的疗效。

【关键词】tenon囊；曲安奈德；黄斑水肿【中图分类号】R446【文献标识码】A【文章编号】1001-5213(2016)09-0138-01 Clinical injection of triamcinolone acetonide for macular edema in Tenon capsule. 【Abstract】Observation sub-Tenon injection of triamcinolone acetonide for the treatment of macular edema.38 cases of macular edema were treated with sub-Tenon injection of triamcinolone acetonide 40mg, before treatment and after treatment for 4,6 months, visual acuity, intraocular pressure, macular thickness were observed compared with statistical analysis. After 4 months and 6 months, visual acuity before treatment, the difference was statistically significant. Thinning of macular thickness after treatment than before treatment were significantly different. There was a significant difference in IOP values before treatment and after treatment, but no cases of acute glaucoma attack.【Key words】tenon capsule; triamcinolone acetonide; macular edema 黄斑水肿在眼底疾病中发生率很高，最常见的病因是视网膜中央静脉阻塞、糖尿病视网膜病变及葡萄膜炎，目前常用的治疗方法有玻璃体腔注射曲安奈德，或者玻璃体腔注射抗VEGF抗体，因前者的副作用及后者对于普通病人的经济承受能力影响，本组采取Tenon囊下注射曲安奈德(triamcinolone acetonide ,TA)治疗黄斑区水肿。

2020年3月康柏西普联合激光光凝治疗白内障术后黄斑囊样水肿的临床效果白雪，刘彩金*，党婷婷（延安市人民医院眼科，陕西延安，716000）摘要：目的探讨康柏西普联合激光光凝治疗白内障术后黄斑囊样水肿的临床效果。

方法选取我院白内障手术术后出现黄斑囊样水肿的患者68例（80只患眼）为研究对象，随机将其分为观察组和对照组，各34例（40只患眼）。

对照组给予激光光凝治疗，观察组在对照组基础上联合康柏西普治疗。

比较两组的治疗效果。

结果治疗后2周，两组的CFT 、眼压、BCVA 及FFA 渗漏率均较治疗前明显改善，且观察组明显优于对照组（P <0.05）；观察组的治疗总有效率明显高于对照组（P <0.05）。

结论康柏西普联合激光光凝治疗白内障术后黄斑囊样水肿的临床效果显著，能有效改善患者的BCVA 。

关键词：康柏西普；激光光凝；白内障；黄斑囊样水肿中图分类号：R776.1文献标志码：A文章编号：2096-1413(2020)07-0089-02DOI:10.19347/ki.2096-1413.202007038作者简介：白雪（1985-），女，汉族，陕西延安人，主治医师，硕士。

研究方向：白内障相关疾病的诊治。

*通讯作者：刘彩金，E -mail :378221175@.Clinical effect of conbercept combined with laser photocoagulation in the treatment ofcystoid macular edema after cataract surgeryBAI Xue,LIU Cai-jin *,DANG Ting-ting(Ophthalmology Department,Yan'an People's Hospital,Yan'an 716000,China)ABSTRACT:Objective To explore the clinical effect of conbercept combined with laser photocoagulation in the treatment of cystoid macular edema after cataract surgery.Methods A total of 68patients (80affected eyes)with cystoid macular edema after cataract surgery in our hospital were selected as the study objects and randomly divided into observation group and control group,with 34cases (40affected eyes)in each group.The control group was treated with laser photocoagulation,and the observation group was treated with conbercept on the basis of the control group.The therapeutic effects of the two groups were compared.Results At 2weeks after treatment,the CFT,intraocular pressure,BCVA and FFA leakage rates in the two groups significantly improved,and those in the observation group were significantly better than the control group (P <0.05);the total effective rate of treatment in the observation group was significantly higher than that in the control group (P <0.05).Conclusion Conbercept combined with laser photocoagulation in the treatment of cystoid macular edema after cataract surgery has a significant clinical effect,it can effectively improve the BCVA of patients.KEYWORDS:conbercept;laser photocoagulation;cataract;cystoid macular edema临床医学随着年龄的增长，白内障的发病率越来越高。

康柏西普眼内注射液治疗视网膜中央静脉阻塞黄斑囊样水肿的疗效观察杨胜信，李沂钢，甘晚妹（广西医科大学第七附属医院梧州市工人医院，广西梧州，543001）摘要：目的探讨康柏西普眼内注射液治疗视网膜中央静脉阻塞（CRVO）继发黄斑囊样水肿（CME）的疗效。

方法选取于我院就诊的42例（42眼）CRVO继发CME患者作为研究对象，收集患者资料并做回顾性分析，所有患者给予康柏西普眼内注射液治疗，观察比较治疗前后视力变化的差异。

结果治疗后7d、1个月、2个月、3个月患者的BCVA及CMT与治疗前相比，差异均有统计学意义（P<0.01）；注射后8眼（19.0%）出现局部球结膜下出血，2眼（4.8%）出现一过性眼压升高。

结论康柏西普眼内注射液治疗CRVO继发CME的疗效确切且安全性高，值得在临床上应用推广。

关键词：视网膜中央静脉阻塞；CME；康柏西普中图分类号：R774文献标志码：A文章编号：2096-1413(2016)18-0017-02The effect of Compaq Sipp intraocular injection in the treatment of central retinalvein obstruction with cystoid macular edemaYANG Sheng-xin,LI Yi-gang,GAN Wan-mei(Wuzhou Gongren Hospital,the Seventh Affiliated Hospital of Guangxi Medical University,Wuzhou543001,China)ABSTRACT:Objective To investigate the effect of Compaq Sipp intraocular injection in the treatment of CRVO with secondary CME.Methods Forty-two CRVO patients with secondary CME(42eyes)in our hospital was selected in the study.The data of patients were collected and analyzed retrospectively,all the patients received Compaq Sipp intraocular injection therapy,the vision differences before and after treatment changes was observed and compared in the study.Results After treatment(7d,1,2,3months)CMT and BCVA was statistically significant different from before treatment (P<0.01),8eyes(19.0%)showed local subconjunctival hemorrhage after injection,2eyes(4.8%)had transient intraocular pressure.Conclusion Compaq Sipp intraocular injection in the treatment of CME with secondary CRVO is effective and safe,which is worthy of clinical application and promotion.KEYWORDS:central retinal vein obstruction;cystoid macular edema;compaq sipp视网膜中央静脉阻塞（central retinal vein obstruction, CRVO）是由于眼底静脉阻塞所致的眼底血管疾病，黄斑囊样水肿（cystoid macular edema,CME）是多种眼底疾病在黄斑区的表现，CRVO后继发CME可导致视力严重受损。

曲安奈德治疗糖尿病黄斑囊样水肿的临床分析梁圆圆【期刊名称】《中国医药指南》【年(卷),期】2013(000)021【摘要】Objective To investigate the triamcinolone acetonide for diabetic macular edema clinical efficacy. Methods August 2011-2013 in January in our hospital 60 cases of cystoid macular edema in patients with diabetes, a total of 84. All patients underwent retrobulbar injection of triamcinolone acetonide in patients after treatment, measurement and evaluation of visual acuity after 1 week of treatment situations;would 1,2,3 months after treatment visual,acuity macular lfuorescein leakage area and central macular thickness than before treatment, the incidence of complications in patients with follow-up. Results 1 week after treatment, visual acuity improved in all patients was 92.86%(78/84);1,2,3 months after treatment macular lfuorescein leakage area was signiifcantly reduced or disappeared, visual acuity and central macular thickness were better than before treatment, the difference was signiifcant, with statistical signiifcance(P<0.05);All patients were followed three month period, the complication rate was 0. Conclusion Triamcinolone acetonide treatment of diabetic macular edema with better treatment, the advantage of fewer adverse reactions, it is worthy of clinical application.% 目的探讨曲安奈德治疗糖尿病黄斑囊样水肿的临床疗效。

康柏西普联合激光治疗视网膜静脉血管阻塞并发黄斑囊样水肿的疗效2鸡西市人民医院158100【摘要】目的：研究康柏西普联合激光治疗的临床疗效，分析该方法在治疗视网膜静脉血管阻塞并发黄斑囊样水肿中的价值。

方法：选择我院于2018年2月至2019年2月期间治疗的的86名视网膜静脉血管阻塞并发黄斑囊样水肿患者，通过双盲法分为各43例的对照组（实施激光治疗）和观察组（实施康柏西普联合激光治疗），比较组间治疗效果。

结果：本次研究中，观察组的CMT、囊样渗漏、弥漫渗漏、局部渗漏发生率明显低于对照组，BCVA明显高于对照组，数据差异具有统计学意义，P＜0.05。

结论：在视网膜静脉血管阻塞并发黄斑囊样水肿患者的治疗中实施康柏西普联合激光治疗，能够改善CMT、BCVA指标，黄斑囊样水肿症状缓解，该治疗方法具有一定的使用价值。

【关键词】视网膜静脉血管阻塞；黄斑囊样水肿；康柏西普；激光视网膜静脉血管阻塞多见于老年人，其发病率与年龄成正比。

该疾病病因复杂，与高血压、高血脂、高血糖等全身疾病有关。

患者视力极度减退、视野缺失，病情较轻者阻塞未累计黄斑，但病程较长者易并发黄斑囊样水肿[1]。

激光治疗利用热效应促使局部组织蛋白质变性凝固，可防止发生新生血管、玻璃体积血，改善视网膜静脉血管缺血症状。

但激光对视网膜静脉血管阻塞并发症的治疗和预防效果并不显著，还需联合药物治疗。

为此本文分析康柏西普联合激光治疗视网膜静脉血管阻塞并发黄斑囊样水肿的疗效，具体如下：1资料与方法1.1.一般资料选择我院于2018年2月至2019年2月期间治疗的的86名视网膜静脉血管阻塞并发黄斑囊样水肿患者，通过双盲法分为各43例的对照组和观察组。

对照组男性23例，女性20例，年龄38-78岁，观察组男性22例，女性21例，年龄36-76岁。

患者一般资料无统计学意义，P＞0.05。

1.1.方法1.2.1对照组对照组予以激光治疗，术前行散瞳处理、局部眼部麻醉，利用Nd:YAG激光治疗机对视网膜病变处进行光凝。

黄斑区格栅样光凝在雷珠单抗治疗糖尿病黄斑囊样水肿过程中的应用时机邹刚;张少弛;容维宁【期刊名称】《宁夏医学杂志》【年(卷),期】2015(037)005【摘要】目的探讨在抗VEGF药物雷珠单抗(Lucentis)治疗糖尿病黄斑囊样水肿过程中传统黄斑区格栅样光凝治疗的时机.方法收集2型糖尿病黄斑水肿患者57例68眼,玻璃体腔注射Lucentis后行黄斑区格栅样光凝.将患者分为2组,即A 组,Lucentis注射1周后行黄斑区格栅样光凝;B组,Lucentis注射1个月后行黄斑区格栅样光凝.2组患者均为每月注射1次Lucentis,共3次.随访观察3个月,统计治疗前后平均矫正视力(BCVA)和平均黄斑中心视网膜厚度(CMT).结果治疗3个月后,1周激光治疗组、1个月后激光治疗组平均矫正视力分别为0.26±0.14、0.25±0.14,平均黄斑中心视网膜厚度分别为(345.78±47.29)、(354.82±132.64) μm,均较治疗前提高或好转,差异有统计学意义(P＜0.05).1周激光治疗组、1个月后激光治疗组前后平均矫正视力的差值分别为0.09±0.03、0.08±0.04,2组差异无统计学意义(P＞0.05).1周激光治疗组、1个月后激光治疗组前后平均黄斑中心视网膜厚度的差值分别为(162.48±57.23)、(87.82±35.67) μm,2组差异有统计学意义(t=6.786,P＜0.05).结论雷珠单抗玻璃体腔注射联合黄斑区格栅样光凝对糖尿病黄斑水肿疗效确切,抗VFGF治疗后尽早行黄斑区格栅样光凝对减轻糖尿病黄斑水肿有更好的效果.【总页数】4页(P416-419)【作者】邹刚;张少弛;容维宁【作者单位】宁夏人民医院眼科医院,宁夏银川750001;宁夏人民医院眼科医院,宁夏银川750001;宁夏人民医院眼科医院,宁夏银川750001【正文语种】中文【中图分类】R774【相关文献】1.黄斑区格栅样光凝与玻璃体腔注射雷珠单抗治疗糖尿病黄斑水肿的疗效观察 [J], 田秀红2.黄斑区格栅样光凝单独或联合雷珠单抗治疗糖尿病性黄斑水肿 [J], 黄建冬;宋振宇3.玻璃体腔注射雷珠单抗联合黄斑区格栅样光凝治疗视网膜分支静脉阻塞继发黄斑水肿的效果 [J], 蓝诚红4.雷珠单抗治疗后不同时机联合黄斑格栅r样光凝对糖尿病黄斑水肿的影响 [J], 李涛;范卫华;吴震5.雷珠单抗联合黄斑区格栅样光凝治疗视网膜分支静脉阻塞的临床疗效及安全性[J], 严槟;尹小芳;叶祖科;卢彦;洪剑威因版权原因，仅展示原文概要，查看原文内容请购买。

复方血栓通胶囊治疗黄斑区视网膜前膜剥膜术后黄斑囊样水肿的疗效观察尹小磊;袁容娣;叶剑【摘要】Objective To evaluate the effect and safety for the treatment of cystoid macular edema due to epiretinal membrane of macula. Methods A retrospective analysis of BCVA and OCT of 16 eyes with cystoid macular edema due to epiretinal membrane of macula were treated with stripping of macula membranes and taken compound Xueshuantong capsule postoperation in our hospital, 2008 January to 2008 December was performed. Results After 3 months were treated with compound Xueshuantong capsule, the BCVA and cystoid macular edema of the patients were significantly improved,however, these were not statistic different between 3 months and 6 months. Conclusion Compound Xueshuantong capsule can be helpful to treat the cystoid macular edema after stripping of macula membranes, but the long-term therapeutic effect of this medicine is unknown.%目的观察复方血栓通胶囊对黄斑区视网膜前膜剥膜术后黄斑囊样水肿的疗效及安全性.方法对14例(16只眼)明确诊断黄斑前膜及黄斑水肿行手术剥膜患者,于术后次日开始服用复方血栓通胶囊,观察视力、相干光断层扫描(OCT)的变化.结果服药3个月后,视力明显提高,黄斑水肿显著减轻,服药6个月后较3个月后视力及黄斑厚度无统计学差异.结论复方血栓通胶囊短期内有助于黄斑区视网膜前膜剥膜术后黄斑囊样水肿的治疗,但长期疗效有待于进一步的研究.【期刊名称】《临床眼科杂志》【年(卷),期】2011(019)003【总页数】3页(P236-238)【关键词】黄斑区视网膜前膜;黄斑囊样水肿;玻璃体切除手术;黄斑前膜剥膜术;复方血栓通胶囊【作者】尹小磊;袁容娣;叶剑【作者单位】100017,北京,解放军第305医院眼科;重庆,第三军医大学大坪医院野战外科研究所眼科;重庆,第三军医大学大坪医院野战外科研究所眼科【正文语种】中文黄斑囊样水肿(cystoid macular edema,CME)是因液体积存在黄斑区外网状层Hen le纤维间而造成的一种常见眼底病变,往往严重损害视力。

黄斑水肿的中西医治疗
魏春惠
【期刊名称】《江苏中医药》
【年(卷),期】2007(039)004
【摘要】黄斑水肿是由于不同眼内病变所引起的一种病理变化过程．可继发于糖尿病、葡萄膜炎、视网膜静脉阻塞、白内障术后等多种疾病。

临床诊断的黄斑水肿是指黄斑中心部位细胞间的液体积聚．分为黄斑囊样水肿和弥漫性黄斑水肿．可严重威胁患者的中心视力．是多种眼病导致视力减退的主要原因，因而引起广泛的重视。

【总页数】2页(P5-6)
【作者】魏春惠
【作者单位】东南大学附属中大医院,江苏南京,210009
【正文语种】中文
【中图分类】R774.5
【相关文献】
1.糖尿病黄斑水肿的中西医治疗新进展 [J], 李佳;王兴荣;张有花
2.视网膜中央静脉阻塞合并黄斑水肿的中西医治疗进展 [J], 刘芳;魏伟
3.视网膜静脉阻塞黄斑水肿的中西医治疗进展 [J], 高荔姗; 钟舒阳; 郝小波; 林柳燕; 盛雪霏; 周智媛; 吴慧玲
4.视网膜静脉阻塞黄斑水肿的中西医治疗进展 [J], 高荔姗; 钟舒阳; 郝小波; 林柳燕;
盛雪霏; 周智媛; 吴慧玲
5.糖尿病黄斑水肿的中西医治疗研究进展 [J], 柴永馨;温莹;毕爱玲;毕宏生
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五苓散结合补阳还五汤加减治疗白内障术后黄斑水肿的临床疗效【摘要】：目的：研究五苓散合补阳还五汤加减治疗白内障黄斑水肿的临床效果。

方法：48例白内障黄斑水肿患者,这些患者被随机分为两组，每组24人。

其中一组接受了传统的西医治疗，而另一组则接受了传统西医治疗的基础上，加入了中药治疗，使用了五苓散合补阳还五汤并根据病情进行调整。

我们比较了这两组患者在治疗前后的疗效、生活质量评分、视力以及黄斑中心亚区域厚度方面的差异。

结果：中药组患者的治疗总有效率为100.00%（24/24）高于常规组的79.17%（19/24）,其差异具有统计学意义(P<0.05)；治疗前,两组患者的生活质量评分、视力、黄斑中心亚区域厚度比较,差异无统计学意义(P>0.05)；治疗后,中药组患者的生活质量评分高于常规组、视力优于常规组、黄斑中心亚区域厚度小于常规组,差异具有统计学意义(P<0.05)。

结论：采用常规西医治疗并辅以五苓散合补阳还五汤的调整治疗方法，对于白内障黄斑水肿患者具有潜在的良好预后效果。

这种治疗方式可以有效减轻黄斑水肿，提升患者的视力，有助于改善他们的生活质量。

这一方法值得被广泛推广和应用。

【关键词】：五苓散；补阳还五汤；加减治疗；白内障黄斑水肿[Abstract]: Objective: To study the clinical effect of Wulingin the treatment of macular edema. Methods: 48 patients with cataract macular edema were randomized into two groups of 24. One group received traditional western medicine treatment, while the other group received traditional western medicine treatment on the basis of traditional western medicine treatment, and it was adjusted according to the condition. We compared the differences in terms of efficacy, quality of life score, visual acuity, and subregional thickness in the central macular area. Results: The total effective rate of patientswas 100.00% (24 / 24) higher than 79.17% (19 / 24) of the conventional group, and the difference was statistically significant (P <0.05); before treatment, the score, vision and macular subregional thickness between the two groups (P> 0.05); after treatment, the QoL score ofthe patients was higher than the conventional group, and the macular subarea thickness was less than the conventional group, and the difference was significant (P <0.05). Conclusion: Using conventional western medicine treatment has a potentially good prognosis forpatients with macular edema. This treatment can effectively reduce macular edema, improve patients' vision, and help improve theirquality of life. This method deserves its widespread promotion and application. [Key words]: Wuling powder; fill Yang and five soup; plus or minus treatment; cataract macular edema白内障是一种常见的眼科疾病，其发病机制涉及晶状体代谢紊乱，导致晶状体蛋白质变性而产生混浊[1]。