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Adakveo® (crizanlizumab-tmca)(Intravenous)Document Number: IC-0513 Last Review Date: 01/04/2022Date of Origin: 12/16/2019Dates Reviewed: 12/2019, 01/2021, 01/2022I.Length of AuthorizationCoverage will be provided for 6 months initially and may be renewed annually thereafter. II.Dosing LimitsA.Quantity Limit (max daily dose) [NDC Unit]:•Adakveo 100 mg/10 mL single-dose vials: 6 vials at weeks 0 and 2 and every 4 weeks thereafterB.Max Units (per dose and over time) [HCPS Unit]:•120 billable units at weeks 0 and 2 and every 4 weeks thereafterIII.Initial Approval Criteria 1Coverage is provided in the following conditions:•Patient is at least 16 years of age; ANDUniversal Criteria•Therapy will not be used in conjunction with voxelotor (Oxbryta) or L-glutamine (Endari);ANDSickle Cell Disease 1-3 †Ф•Patient has a confirmed diagnosis of sickle-cell disease, of any genotype (e.g., HbSS, HbSC, HbS/beta0-thalassemia, HbS/beta+-thalassemia, and others) as determined by one of thefollowing:o Identification of significant quantities of HbS with or without an additional abnormal β-globin chain variant by hemoglobin assay; ORo Identification of biallelic HBB pathogenic variants where at least one allele is the p.Glu6Val pathogenic variant on molecular genetic testing; AND•Patient had an insufficient response to a minimum 3-month trial of hydroxyurea (unless contraindicated or intolerant); AND•Patient experienced one or more vaso-occlusive crises (VOC)* in the previous year despite adherence to hydroxyurea therapy*VOC is defined as an event prompting either a visit or outreach to the provider which results in a diagnosis of VOC being made necessitating subsequent interventions such as narcotic pain management, non-steroidal anti-inflammatory therapy, hydration, etc.†FDA Approved Indication(s); ‡ Compendia Recommended Indication(s); ФOrphan DrugIV.Renewal Criteria 1,3Coverage can be renewed based upon the following criteria:•Patient continues to meet the universal and other indication-specific relevant criteria identified in section III; AND•Absence of unacceptable toxicity from the drug. Examples of unacceptable toxicity include: severe infusion related reactions (e.g., pain, headache, fever, chills, nausea, vomiting,diarrhea, fatigue, dizziness, pruritus, urticaria, sweating, shortness of breath or wheezing),etc.; AND•Disease response compared to pretreatment baseline as evidenced by a decrease in the frequency of vaso-occlusive crises (VOC) necessitating treatment, reduction in number orduration of hospitalizations, and/or reduction in severity of VOCV.Dosage/Administration 1VI.Billing Code/Availability InformationHCPCS:•J0791 – Injection, crizanlizumab-tmca, 5 mg; 1 billable unit = 5 mgNDC:•Adakveo 100 mg/10 mL (10 mg/mL) single-dose vial: 00078-0883-xxVII.References1.Adakveo [package insert]. East Hanover, NJ; Novartis Pharmaceuticals, Inc., July 2021.Accessed November 2021.2.Bender MA. Sickle Cell Disease. 2003 Sep 15 [Updated 2021 Jan 28]. In: Adam MP,Ardinger HH, Pagon RA, et al., editors. GeneReviews® [Internet]. Seattle (WA): Universityof Washington, Seattle; 1993-2019. Available from:https:///books/NBK1377/.3.Ataga KI, Kutlar A, Kanter J, et al. Crizanlizumab for the Prevention of Pain Crises inSickle Cell Disease. N Engl J Med. 2017 Feb 2;376(5):429-439. doi:10.1056/NEJMoa1611770. Epub 2016 Dec 3.4.Yawn BP, Buchanan GR, Afenyi-Annan AN, et al. Management of sickle cell disease:summary of the 2014 evidence-based report by expert panel members. JAMA. 2014 Sep 10;312(10):1033-48.Appendix 1 – Covered Diagnosis CodesAppendix 2 – Centers for Medicare and Medicaid Services (CMS)Medicare coverage for outpatient (Part B) drugs is outlined in the Medicare Benefit Policy Manual (Pub. 100-2), Chapter 15, §50 Drugs and Biologicals. In addition, National Coverage Determination (NCD), Local Coverage Article (LCAs) and Local Coverage Determinations (LCDs) may exist and compliance with these policies is required where applicable. They can be found at: https:///medicare-coverage-database/search.aspx. Additional indications may be covered at the discretion of the health plan.Medicare Part B Covered Diagnosis Codes (applicable to existing NCD/LCA/LCD): N/A。
1、安素/肠内营养粉剂（市场价90元）【药品名称】通用名称：肠内营养粉剂汉语拼音：changneiyingyangfenji【成份】蛋白质、脂肪、碳水化合物、维生素、矿物质【性状】本品为淡黄色粉末，气芳香、味甜。
【适应症】安素粉剂可作为唯一营养来源或部分营养补充，适用于成人及四岁或四岁以上儿童，可口服或管饲。
【规格】400g × 1【用法用量】禁止安素（Ensure）粉剂胃肠外注射或静脉内使用。
安素粉剂可作唯一营养来源或营养补充，打开容器后注意防腐以避免污染，安素粉剂在室温下或冷却后服用。
【不良反应】没有肠内营养禁忌症的人正确服用时一般不会出现副作用。
【禁忌】安素粉剂忌用于不能口服或肠内进食的情况，上述情况包括肠梗阻、严重的短肠综合症或高排泄量的痿，半乳糖血症患者禁止使用。
【作用类别】【孕妇及哺乳期妇女用药】无特殊要求，应根据营养需求调整用量，详见[用法用量]【儿童用药】4岁以下儿童不宜服用本品【老年用药】无特殊要求,应根据营养需求调整用量，详见[用法用量]【注意事项】安素粉剂的正确冲调对于防止插管堵塞和保证全部的营养转运是重要的，安素粉剂不能胃肠外注射或静脉内使用。
【药物相互作用】尚无相关报告【贮藏】冲调好的安素应该立即服用或加盖冰箱保存,在24小时内服完,开盖的罐子应该用盖子盖住,贮藏,一旦打开,安素粉剂应该在3星期内用完.【包装】每个铁质听内含400克安素粉2、肠内营养粉剂（雅培制药，市场价78元）【商品名】安素粉(TP/Ensure)【通用名】肠内营养粉剂【适用症】把粉剂的安素加进温开水中拌匀后制成安素液，不论作为管饲、流质膳或营养添加剂，都能提供完整而均衡的养分，应在医生或营养师的指导下，严格遵嘱使用。
【成份】水解玉米演粉，玉米油，酪蛋白钙和钠，蔗糖，矿物质：（枸橼酸钾、枸橼酸钠、氯化钾、三磷酸钙，硫酸锌，硫酸亚铁，硫酸锰，硫酸铜，钼酸钠，氯化铬，硒化钠，碘化钾）。
分离大豆蛋白，人造香兰素，大豆卵磷酯，维生素：（氯化胆碱、抗坏血酸、醋酸生育酚，烟酰胺，泛酸钙，盐酸吡哆醇，盐酸硫胺，核黄素，棕榈酸维生素A，叶酸，生物素，维生素K1，氰钴胺，维生素D3）。
维态美复合益生菌说明书摘要：1.引言2.产品介绍3.主要成分4.功效与作用5.适用人群6.使用方法与注意事项7.储存方法8.结束语正文：【引言】维态美复合益生菌是一款集多种益生菌于一身的功能性食品，致力于为消费者带来健康的生活。
本文将详细介绍维态美复合益生菌的产品特点、成分、功效、适用人群及使用方法等。
【产品介绍】维态美复合益生菌是一种含有多种活性益生菌的固体饮料，采用独特的生产工艺和科学配方，确保益生菌的活性和功效。
本产品适用于关注肠道健康、追求高品质生活的各类人群。
【主要成分】维态美复合益生菌的主要成分包括：嗜酸乳杆菌、双歧杆菌、植物乳杆菌、鼠李糖乳杆菌、嗜热链球菌等多种益生菌。
这些益生菌有助于维持肠道菌群平衡，提高免疫力，促进营养物质的消化吸收。
【功效与作用】1.改善肠道菌群平衡，抑制有害菌的生长，维护肠道健康。
2.提高免疫力，增强抵抗力，预防多种疾病。
3.促进营养物质的消化吸收，提高营养利用效率。
4.有助于维持肠道正常蠕动，预防便秘和腹泻。
5.减轻肠道负担，降低肠道疾病风险。
【适用人群】1.肠道功能不佳、易腹泻或便秘的人群。
2.免疫力较低、易感冒发烧的人群。
3.关注肠道健康、追求高品质生活的人群。
4.饮食不规律、生活压力大的人群。
5.孕妇、老年人、儿童等特殊人群。
【使用方法与注意事项】1.建议每天食用1-2 次，每次1 袋。
可随餐食用，亦可餐前或餐后食用。
2.为确保益生菌的活性，请将产品存放在阴凉、干燥、通风的环境中，避免阳光直射。
3.本产品为食品，不能替代药物治疗。
如病情严重，请及时就医。
4.孕妇、哺乳期妇女及儿童应在医生建议下使用。
【储存方法】请将维态美复合益生菌存放在阴凉、干燥、通风的环境中，避免阳光直射。
建议在保质期内尽早食用，以确保产品品质。
【结束语】维态美复合益生菌是一款适合广大人群的肠道健康产品，通过多种益生菌的协同作用，有助于维护肠道菌群平衡，提高免疫力，促进营养物质的消化吸收。
Jean-Yves Berthon, Greentech“EXPLORING THE FUTURE OF SKIN BEAUTY”GO FUTURE: FACIAL CAREThe main drivers of facial careSPOTLIGHT:THE MICROBIOMEA long way to go?MAY SHANA’ABeiersdorfOpening new doorsfor cosmetics9 / 2018COSMETICS | SPRAY TECHNOLOGY | MARKETING E51280Nature’sCyclomethicone FluidDriving innovation with plant-based silicone alternatives: + 100% Natural + Partially volatile+ Luxurious & light after-feel + Enhanced slip & skin-feelLexFeel WOW ®LexFeel WOW ®DTRequest samples at Alternative Preservation Naturals Palm-Free Sun CareSilicone Alternatives LexFeel WOWCyclopentasiloxaneGraphical display of skin feel sensory attributes(Scale: -2 to 2. n=9)SpreadabilityAfter-feel Luxurious FeelMoisturizationSlipAbsorptionSilkiness-2.0-1.00.01.02.012K orea-inspiredingredient forcrystal-clear skin3 Editorial10 MARKETS & COMPANIES10 News12 GO FUTURE: FACIAL CARE12 Dr Sarah Christina Pütsch: Korea-inspired crystal-clear skin16 Mélanie Coirier, Emilie Lasjaunias, Brigitte Closs, Silab:Oxygen to combat blue light effects18 Michele Marchini, Svetlana Vinogradova, DSM:The main drivers of facial care23 Michelle Strutton, Mintel: Global launches24 Júlia Comas, Dr Olga Laporta, Marie Ollagnier, Dr Núria Almiñana, Dr Raquel Delgado, Lipotec: For strengthened skin28 INGREDIENTS28 IFSCC: A science close-up30 Ingredients news35 Formulations: Body care36 SPOTLIGHT: THE MICROBIOME36 Dr Karl Lintner, Kal‘Idées: A long way to go?16O xygenation reinvigoratesthe skin in conditions ofdigital pollution18F ind out about the main trendclusters driving facial careContentsCOSSMA 9/201856A bout Greentech’sendeavours to explore the future of skin beauty36A re microbiome- related beauty claims credible?COSSMA 9/201840 MARKETING40 Interview with Uli Osterwalder, Consultant :A new option for SPF assessment?42 Interview with May Shana’a, Beiersdorf :Opening new doors for cosmetics46 Anne Charpentier, Skinobs : Testing options for hair care 48 Star of the Month : Magnetic mask kit50 PACKAGING50 Luxe Pack : Luxury at its best52 Gregor Spengler, Etma : Tubes – An abundance of new ideas 54 Packaging news56 PERSONALITIES & PROFILES56 Interview with Jean-Yves Berthon, Greentech :Exploring the future of skin beauty 59 People58 SERVICES8 Download List 61 Events Diary 62 Suppliers‘ Guide 65 Advertisers’ Index 66 Masthead Page 66 PreviewFront cover picture: Greentech42M ay Shana’a from Beiersdorf about the latest R&D findingsContents1stAirless pump made of 4 components onlyWORKS FOR ALL VISCOSITIESRPC BRAMLAGE - AirFree ® Customer Service :France : +33 4 74 81 74 81 Germany : +49 7243 5866 69 Spain : +34 93 777 24 48* P a c k a g i n g c e r t i fi e d b y E c o c e r t a n d C o s m o s o r g a n i s a t i o n sPROTECT YOUR FORMULA & ACT FOR THE ENVIRONMENT#100%PLASTIC #RECYCLABLE #INNOVATIVEDARE TO CHOOSE THE N°1SUSTAINABLE AIRLESS DISPENSERp h o t o s : M a r y V i o l e t (w o m a n ), F o t o l i a .c o m , A f r i c a S t u d i o (o i l ), I l d i P a p p (f r u i t ), S h u t t e r s t o c k .c o mNEW ENTRYBASF | MBBT*, an ingre-dient of BASF’s product Tinosorb M , has been entered into Annex VI of the EU Cosmetic Regu-lation as a nano-sized UV filter. MBBT is now BASF’s third UV filter in nano form to be ap-proved for use in cosmet-ics in Europe after Tino-sorb A2B in 2014 and Z-Cote in 2016.* Methylene Bis-Benzotriazolyl TetramethylbutylphenolFOR GREEN SCENTSSYMRISE | Symroxane is a multifaceted fragrance ingre-dient from the Symrise Aroma Molecules . It lends fragrances an elegant note and increases the caring effect for beauty care products.Fragrance ingredient made from renewable materialMicrobiome protectionGIVAUDAN ACTIVE BEAUTY | 10 personalised fragrances were combined with Revivyl , the micro-biome protecting ingredient. Thus, Givaudan created the first person-alised perfumes that protect the skin microbiota./activebeautyPersonalised fragrance protects the microbiotaSUPERFRUITS FOR THE SKINASHLAND | The stress hor-mone cortisol can have a negative effect on our bodies. Suprastim can help skin con-trol the 11β-HSD1 enzyme, which is knownto regulate cortisol levels in skin cells. The ingredient, sourced from the Amazonian super fruit camu camu, has antioxidant properties, increases collagen production, reduces pigmentation and can help reduce visible signs of skin fatigue./suprastimNow part of Annex VICamu camu is anAmazonian super fruitINGREDIENTSNews– ADVERTISEMENT –N e w s O F T H E M o n t hp h o t o : S o f i a Z h u r a v e t c , S h u t t e r s t o c k .c o mCroda Tooth Foam Daito KaseiHigh Loaded Fragrance Shower Gel DKSHBody Milk for Care Moments Evonik Dr. Straetmans Slimming Body Lotion, O/W GfN SelcoCoffee Butter TiO 2 Sunscreen SPF 30HallstarMMP Inc.Self Tanning Stick NaturochimNatural Deep Hydration Milk Nordmann, Rassmann Natural Beauty Body Butter Roelmi HPCIrresistible Touch Body Balm Sederma Velvet Body Fluid SisternaCharcoal Purifying Micellar Lotion The Cosmetic BoxDaily Cream Exfoliating Shower WorléeNatural Baby Cream Zschimmer & SchwarzIn the October issue, we will be focusing on formulations for anti-ageing products. In our November issue, formula-tions for sprays and foams will take centre stage. All of the information published here has been carefully assembled. Neither the publishers nor the developers of these formu-lations can accept responsibility for its safety or accuracy.More information at , web code 100068Your access codes for September :User name: cossma9Formulations | This month’s selection of formulations provides you with a broad choice of fascinating ideas for body care products. Apart from traditional body creams, butters, lotions and milks you will find concepts for shower gels, cleansing and self-tanning sticks, slimming products, body mists, hand creams and washes as well *Additional information can be found on the Internet – see the Internet panel– ADVERTISEMENT –A new option for SPF assessment?Interview | Uli Osterwalder compares the in vivo SPF goldstandard with current alternatives and points out the advantages of the hybrid diffuse reflectance method (HDRS).p h o t o s : S O F W , T i e r n e y M J (l e a d p h o t o ), S h u t t e r s t o c k .c o mCOSSMA: What are the advantages of the in vivo SPF gold standard? The Sun Protection Factor (SPF) is a universal metric to characterise sun-screens. This is useful for all individ-uals, even if their skin’s sensitivity to sun exposure differs tremendously. To take an example: a sunscreenscreens. In addition, sunscreens do not cover the whole UV range equally well, especially not in the UVA1 re-gion from 340 to 400nm.There is generally too high an expec-tation into the accuracy of this bio-logically determined metric, e.g. it is statistically perfectly ok if a nominal SPF 30 sunscreen is retested with a result of an SPF of 27 or 33. Some consumers and consumer magazines though have not yet understood that these values can all be considered equivalent.Furthermore, there is a seasonal vari-ation in SPF testing, e.g. tests carried out in summer may lead to SPF val-ues that are up to 30% lower. This of course makes in vivo testing difficult.Interview with:Uli Osterwalder, Consultant, Sun Protection Facilitator, Basel, Switzerland uli.osterwalder@ sunprotection.co www.sunprotection.coN N with SPF X provides X-fold protectionagainst the erythema causing radia-tion when analysed under laboratory conditions of SPF testing. The ac-tion spectrum of this process is very closely correlated to the non-mela-noma skin cancer action spectrum; hence the SPF is also some measure for skin cancer prevention.What are the disadvantages?mple notion that SPF X protects X times longer than the self-protection time may lead to over-interpretation and a false sense of security in re-al-world conditions. People in gen -eral do not use enough sunscreen and do not uniformly distribute sun-MARKETINGWhat alternatives are there?The alternative SPF methods (see fig.) currently available have recently been discussed in an article*. We can differentiate between in-vivo, in-vitro and in-silico methods. The most promising approach currently is the hybrid diffuse reflectance method (HDRS) because it combines the best of all alternatives. In spite of the fact that skin is involved for testing, which makes it universally applica-ble, HDRS is a non-invasive method;it is just a physical measurement and not a biological creation of erythema.What are their advantages?HDRS uses the skin as a substrate, i.e. any product that serves as a sun-screen can also be tested. But con-trary to the gold standard in which irradiation induces an erythema re-sponse, DRS works only with a non-invasive physical response. It leads directly to the UVA-PF value. For the SPF, the missing signal in the UVB region is extrapolated from in vitro data. A potential lack of photo-stability is taken into account by ir-radiation and transmission measure-ment on PMMA plates.In-vitro and in-silico methods do not involve human skin at all. This means that the performance of for-mulations with new ingredients that have not been safety-tested can also be determined. Generally, trust in SPF results can be increased by us-ing several methods simultaneously.What are their shortcomings in comparison to the in vivo SPF gold standard?The major drawback of all in-vitro transmission methods is the fact that plastic plates cannot mimic well enough all interactions between skinRobert M. Sayre and others over 30years ago. It is successfully used todetermine UVA protection, e.g. as ISO24443 standard and to label criticalwavelengths or the UVA/UVB ratio.In silico methods have also beenaround for almost 20 years and arenow available on the Internet as theBASF sunscreen simulator or the DSMsunscreen optimizer. In silico meth-ods are based on the UV filter contentand provide a convenient plausibil-ity check, e.g. if a sunscreen contains9% UV filter and claims SPF 50+,authorities may ask for the data orretesting.What does the approach of the ISOWorking Group 7’ in finalising thevalidation methodology for thenew methods consist of?This is a very good question, whichis currently being debated in the ISOSun Protection Working Group ofthe Cosmetic’s Technical Committee(ISO/TC 217, WG 7). In my view, val-idation should follow a standard sta-tistical and generally accepted proce-dure, which has been established byISO, FDA or the scientific community.There is no need to reinvent thewheel; the SPF is not the first meth-odology where new, more efficientand safer methods have to be val-idated against a traditional goldstandard.On the other hand, it is up to the in-dustry experts to set the acceptancecriteria for a new method. Q* Osterwalder et al, SPF assessment revisited – Statusand Outlook, SOFW, Journal 04/18, 144, 2018The article mentioned can be foundon the Internet – see Internet paneland the whole variety of products.Hence, the behaviour of an unknownproduct on the PMMA plates maybe different than in reality on skin,and this then also applies to the SPFvalues.Furthermore, the irradiation step isalso carried out on PMMA plates. Apotential photodegradation of UV fil-ters may also be different than on theskin and in addition, a potential pho-totoxicity effect may be missed. Thephototoxicity effect can be assessedby in-vitro 3T3 N RU phototoxicitytest (OECD No 432) instead.Why have so many attempts failedto validate in vitro against in vivo?There are several reasons. The firstone is the in vitro transmissionmethod itself. As elaborated above,this method can be summarised asfollows, plastic (PMMA) ≠ skin, aplastic plate is currently not able tomimic skin for all types of sunscreenformats and fails to assess if productscontain watersoluble UV filters. Thesecond reason is the rather high var-iability of the in vivo gold standarditself (ISO 24444), especially betweendifferent laboratories. This meansthat a proper validation procedurerequires a lot of in vivo testdata, aminimum of 4 different laboratories.This is expensive and so far, the in-dustry has shied away from fundingsuch a validation sufficiently.What in silico and in vitro tools arethere to support in vivo values?The in vitro transmission methodwas first developed by Brian Diffey,SPF gold standard and alternatives: Classification of assessment method according to typeMARKETINGEleganceTOLY | The new Daisy Jar is double-walled and has a chic and luxurious look. This new standard version. It comes in dif-ferent sizes and can be decorated as required. Thus it offers all the en-ticing aesthetics and clarity of glass.ADDING NATUREAMK VISION WOOD | If the idea is toemphasise the organic character of cosmetics, eco-friendly wooden details will add a little bit of nature to packaging. AMK Vision Wood presents new FSC-certified wooden closures in various finishes and colours for jars in differentsizes and for tubes, at Cosmetic Business in Poland from September 26–27.www.amk-visionwood.eu , Wooden closures for a green lookHealthy Underarm Lavanila is well protected in EVOH* sheath, which protects from oxygen. When open,the tube’s collar moves up, opening the valve to allow the formula to be dispensed. When closed, a ridge in the cap pushes the collar down, which closes the valve and seals off the formula.With the soft brush, the mask can be applied very gently.*an ethyl/vinyl alcohol copolymer)Double-walled jar p h o t o s : A M K V i s i o n W o o d , Q u a d p a c k , T o l yThe product is simply brushed onPACKAGINGNews– ADVERTISEMENT –of a complete factory for13 CAPPING / FILLING MACHINES incl. “Galdi”“Marin”, “Costec” (incl. 2008-2007); 3 capping machines “Costec”“Marin”; 6 FILLING MACHINES incl. “Costec” “Gibo.Matic”;rotary unscramblers “Ronchi”, “Fava”;rotary orientators ;PACKAGING incl.6 palletizers incl. “Comaco”, “Zecchetti““TMG”; 7 cartoning machines “FTP Automazioni” “TMG”; 3 carton forming machines “Bini&” and “TMG”; 2 case packing machines incl. “TMG”; packaging machine “KFT”; carton cover positioner “Bini&C”; (adhesive) labelling machines incl. “Arca Sistemi”, “P bellers”; wrapping machines “Pieri”, “Robopac”; autom. shrink wrapper with shrink oven; bundling machine; heat-shrink oven;continuous mixer “Bran&Lubbe”; osmosis plants “Castagnetti”; TANKS upto 170.000 l incl. tanks with (heated) stirrer,polypropylene tanks, (insulated) tanks, tanks in insulated fiber-glass, fiberglass tanks incl. stirrers, horiz. tanks in fiberglass;Viewing: 12 and 13 September from 9.00 to 17.00 hrsVia Dell’Industria, 11 Località Paludi – 32016 Pieve D’Alpago (IT )Liquid Detergents Filling & Packaging LinesCLOSING : Thursday 20 SEPTEMBERONLINE AUCTIONF o t o : N i k o l a y B a s s o v /s h u t t e r s t o c k .c o m。
产品使用说明书Evcare HOT艾菲凯HOT特性Evcare HOT是一种热感整理剂，能赋予织物温暖的感觉。
适用于棉、麻、黏胶等纤维素纤维及其混纺织物。
化学组成：特殊蓄热相变材料的复配物离子性：非离子外观：无色至微黄色浆状体溶解性：可与水任意比例稀释注意事项：处理荧光增白剂处理过的织物前应检查是否会泛黄应用特性：1.赋予织物储存和释放能量的功效，从而起到保温效果2.不含APEO、符合OEKOTX100标准（Ⅱ类）使用方法：1.浸轧法：80-180g/L，轧余率70-80%。
2.浸渍法：5%左右，用HAC调节pH值至弱酸性，40-50℃，20-30min，控制带液量在80%左右。
3.处理后的织物100-130℃烘干，150-170℃定型30-45秒。
4.若要增强耐洗性，可加入催化剂5-10g/L。
5.备注：根据实际情况酌情调整使用量；对甲醛含量有特别要求的订单，建议处理的织物于40-60℃的温水中水洗一遍。
包装：30公斤塑胶桶贮存：通风、避光。
若存放在原包装密闭容器中于 0-35℃下该产品的贮存期至少为12个月。
包装桶一旦打开应尽快用完，如果没有用完，请将其密封好。
安全：据本公司多年积累的经验以及本公司收集到的其他资料，使用本产品时，应当采取处置化学品所需的必要的安全预防措施，并遵守本公司安全资料中的注意事项和建议。
用户需知本资料是根据本公司现有的技术知识和经验编写的。
由于在加工和应用本公司产品的过程中有许多影响因素, 这些数据不能代替加工者自己的研究和测试结果, 建议加工者使用前进行必要的试验。
本资料在法律上也不保证本产品在某些性质上完全正确,或者对特殊的用途完全适用。
本资料中的任何描述、图画、照片、资料,特性,重量等可以在没有事先通知的情况下进行调整,且不构成达成一致的产品合同质量。
使用本产品的用户有责任遵守本资料的所有权及现行的法律法规。
符合下游纺织市场要求的责任应由纺织品加工者承担。
多替阿巴拉米片说明书【药品名称】通用名称：多替阿巴拉米片商品名称：绥美凯®；TRIUMEQ®英文名称：Dolutegravir Sodium, Abacavir Sulfate and Lamivudine Tablets汉语拼音：Duoti Aba Lami Pian【成份】本品为复方制剂，每片含多替拉韦钠（以多替拉韦计）50mg、硫酸阿巴卡韦（以阿巴卡韦计）600mg和拉米夫定300mg。
【性状】本品为薄膜衣片，除去包衣后显白色或类白色。
【适应症】本品适用于治疗感染人类免疫缺陷病毒（HIV）的成人和12岁以上青少年（体重至少为40 kg）。
在感染HIV患者中，无论患者人种如何，开始使用含阿巴卡韦的产品治疗前，应当筛查是否携带HLA-B*5701等位基因。
如果已知患者携带HLA-B*5701等位基因，不应当服用含有阿巴卡韦成份的产品。
【规格】每片含多替拉韦钠（以多替拉韦计）50mg、硫酸阿巴卡韦（以阿巴卡韦计）600mg和拉米夫定300mg。
【用法用量】本品应在具有HIV感染治疗经验的医师指导下服用。
剂量成人和青少年（体重至少为40 kg）对于成人和青少年，本品的推荐剂量为每次一片，每天一次。
如果成人或青少年的体重低于40 kg，不应当给予本品，因为本品是固定剂量片剂，不能减少剂量。
本品是固定剂量片剂，不能用于需要剂量调整的患者。
如果需要停用活性成分之一或对其实施剂量调整，可以使用单独的多替拉韦、阿巴卡韦或拉米夫定制剂。
在这些情况下，医师应当参考这些药品各自的产品信息。
漏服如果患者漏服一次本品，并且离下次服药还有4小时以上，应当尽快服用本品。
如果离下次给药不到4小时，患者不应当服用已漏服药物，只需重新恢复平常的给药计划即可。
老年患者在年龄大于等于65岁的患者中，多替拉韦、阿巴卡韦和拉米夫定的用药数据有限。
没有证据表明，老年患者需要与年轻成人患者不同的剂量（见【药代动力学】）。
唯优美产品介绍文案
唯优美是一家专业的化妆品品牌，致力于为女性创造出更加自然、健康、美丽的肌肤。
我们的产品坚持选用优质原材料，无添加有害成分，安全可靠，达到了最佳护肤效果。
我们的产品系列包括：
1. 面部护肤系列：包括洁面、爽肤水、面霜、面膜等产品，能够深度清洁肌肤、补水、保湿、提亮肤色，让您的肌肤光滑度滋润。
2. 眼部护理系列：专注于眼周肌肤的细致呵护，保护您的眼周肌肤不受环境影响，以及延缓衰老的速率。
3. 唇部护理系列：保湿、滋润和唇部塑形，让您的嘴唇时刻保持美丽动人，远离干燥、裂开和褪色等问题。
总之，唯优美致力于美丽、自然、健康的肌肤效果，要让每位女性都无忧无虑，信心满满地展现自己的美丽。
一直点一种眼药水（艾唯多）好不好，治疗方法眼药水是一种直接涂于眼睛的药物，用于治疗眼部问题。
艾唯多（Alcon ）是一种常见的眼药水，用于缓解眼睛干燥、酸痛、疲劳等症状。
但是，使用同一种眼药水长期治疗也不是一个好习惯。
本文将分析使用同一种眼药水的利弊和使用方法以及注意事项。
一直使用同一种眼药水的利弊优点：1. 熟悉方便一直使用同一种眼药水能让使用者熟悉这种眼药水的使用方法和效果，方便掌握每次使用的药量和药效，避免使用不恰当或者过量的情况。
2. 可能提高疗效在某些情况下，使用同一种眼药水可能会提高疗效，因为这种药水的药理成分可能已经针对特定的眼部问题做了精确的调配。
此外，如果使用者对这种眼药水有很好的反应，那么使用同种药品可能会更加有效。
缺点：1. 可能产生抗药性如果一个人一直使用同一种眼药水，那么他的身体逐渐适应这种药物成分，可能会减少对药物的反应。
此外，抗药性也会限制眼药水的使用范围，导致某些眼部问题难以治疗。
2. 可能增加不良反应有些人可能对某些药物成分过敏或者产生不良反应，在长期使用同一种眼药水的情况下，这种现象可能更加明显。
艾唯多治疗方法1. 使用前清洗手部清洗眼药水的使用者的手部是非常重要的，因为眼药水可能会污染。
洗手可以避免将细菌或其他有害物质带入眼睛，从而产生疾病。
2. 使用正确的剂量根据医生的推荐和药物说明书上的指引，使用正确的剂量非常重要。
使用太多的药物会增加副作用的风险，使用太少的药物可能无法治疗眼部问题。
在使用眼药水之前，请阅读说明书，并查看药物的药量和应用频率。
3. 使用正确的保存方法正确保存眼药水也尤为重要，不管是新开的眼药水，还是已经使用了一段时间的。
一旦打开瓶子，就可能会增加微生物繁殖的机会。
请保证药瓶盖子紧固，储存在干燥，室温（不超过25度）的地方。
注意事项：1. 注意卫生在使用之前和使用后，请注意卫生。
务必清洗双手，以防污染眼药水。
另外，在使用眼药水之前，请清理和擦拭任何污染物。
维态美复合益生菌说明书摘要：一、产品简介二、成分与功效三、适用人群四、使用方法五、注意事项六、总结与推荐正文：一、产品简介维态美复合益生菌是一款致力于改善人体肠道微生态的保健品。
它通过科学配比，含有多种有益菌株，有助于维护肠道健康，提高身体免疫力。
本文将为您详细介绍维态美复合益生菌的成分、功效、适用人群、使用方法及注意事项。
二、成分与功效维态美复合益生菌中含有多种有益菌株，如乳酸杆菌、双歧杆菌等。
这些菌株具有以下功效：1.调节肠道菌群平衡：抑制有害菌生长，促进肠道有益菌繁殖，维护肠道生态平衡。
2.提高免疫力：促进免疫细胞活性，增强人体抵抗力。
3.改善消化功能：帮助分解食物，提高消化吸收能力。
4.预防便秘和腹泻：保持肠道水分平衡，预防便秘和腹泻等肠道问题。
5.降低胆固醇：抑制胆固醇合成，降低血液中的胆固醇水平。
三、适用人群维态美复合益生菌适用于以下人群：1.肠道功能紊乱者：如便秘、腹泻、腹痛等。
2.免疫力低下者：容易感冒、生病的人群。
3.饮食不规律者：如长期外卖、高脂饮食等。
4.经常出差或生活压力大者：生活节奏快，肠道健康易受损。
5.关注健康的老年人：随着年龄增长，肠道菌群失衡现象常见。
四、使用方法1.口服：每日2次，每次1粒，空腹或饭后服用。
2.储存：置于阴凉干燥处，避免阳光直射。
3.建议持续服用：益生菌效果需要一段时间才能显现，建议长期坚持使用。
五、注意事项1.孕妇、哺乳期妇女及过敏体质者慎用。
2.慢性病急性发作期患者请在医生指导下使用。
3.避免与抗生素同时使用，如需使用抗生素，请间隔2-3小时后再服用益生菌。
4.饮食调整：同时注意饮食均衡，多吃蔬菜水果，避免过多油腻食物。
六、总结与推荐维态美复合益生菌是一款有益于肠道健康、提高免疫力的保健品。
通过本文的介绍，相信大家对这款产品的成分、功效、适用人群、使用方法和注意事项有了更深入的了解。
在注重饮食调理的同时，适量补充益生菌，有助于维护肠道微生态平衡，提高生活质量。
