不同来源肾眭蛋白尿与血脂组分及超敏C反应蛋白水平相关性研究
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超敏C-反应蛋白与血脂检验在糖尿病新发患者诊断中的应用研究摘要:目的:研究在新发糖尿病患者临床诊断中血脂、超敏C-反应蛋白检验的应用价值。
方法:研究对象选择于2021.10~2022.10就诊于我院的新发糖尿病患者72例,并选择同期健康体检者72例,分别纳入试验组和对照组,检测和对比血脂和超敏C-反应蛋白水平。
结果:与对照组对比,试验组低密度脂蛋白、三酰甘油、血清总胆固醇明显较高,高密度脂蛋白水平明显较低,超敏C-反应蛋白明显较高(P<0.05)。
结论:在新发糖尿病患者临床诊断中血脂、超敏C-反应蛋白检验价值较高,可有效诊断新发糖尿病,建议推广。
关键词:新发糖尿病;血脂;超敏C-反应蛋白;诊断Abstract: Objective: To study the application value of blood lipid and hypersensitive C-reactive protein test in the clinical diagnosisof new diabetes patients. Methods: 72 new diabetic patients and 72 healthy diabetic patients in our hospital from 10-10 to 2022 were selected and included in the test group and the control group todetect and compare blood lipid and hypersensitive C-reactive protein levels. Results: Compared with the control group, LDL, triacylglycerol, serum total cholesterol were significantly higher, and higher (P<0.05). Conclusion: In the clinical diagnosis of new diabetes patients, C-reactive protein test is of high value, which can effectively diagnose new diabetes, and it is suggested to promote it.Key words: new-onset diabetes; blood lipid; hypersensitivity C-reactive protein; diagnosis在临床上糖尿病作为一种发病率较高的内分泌障碍性疾病,特征为发展慢、病程长等,在发病早期特征并不明显,极易发生误诊和漏诊情况,一旦不及时治疗,会对多个器官和组织造成损伤,导致各种并发症发生[1]。
血、尿β2—微球蛋白与超敏C反应蛋白水平在早期2型糖尿病肾病中的临床意义目的探讨血、尿β2-微球蛋白与超敏C反应蛋白水平在早期2型糖尿病肾病中的临床意义。
方法选取2016年6月~2017年6月我院收治的早期2型糖尿病肾病患者60例作为观察组,根据病情严重程度将观察组分为轻度损伤组、中度损伤组和重度损伤组,每组20例;选取60例健康志愿者作为对照组。
检测各组中的血、尿β2-微球蛋白与超敏C反应蛋白水平。
结果观察组中轻、中、重度损伤组的血、尿β2-MG与hs-CRP水平均显著高于对照组,且重度损伤组的上述指标水平均高于中度损伤组、轻度损伤组,中度损伤组的上述指标水平均高于轻度损伤组,差异有统计学意义(P<0.05)。
结论血、尿β2-MG与hs-CRP 对糖尿病肾病的诊断具有一定的临床价值。
[Abstract] Objective To explore the clinical significance of serum and urinary β2-microglobulin and high sensitivity C-reactive protein level in early type 2 diabetic nephropathy. Methods Sixty patients with early type 2 diabetic nephropathy treated in our hospital from June 2016 to June 2017 were selected as the observation group and they were divided into mild injury group (n=20),moderate injury group (n=20)and severe injury group (n=20)according to the severity of the disease. Sixty normal volunteers were selected as the control group. The serum and urinary β2-microglobulin and high sensitivity C-reactive protein level among the groups were detected. Results In the observation group,serum and urinary β2-microglobulin and high sensitivity C-reactive protein level in mild injury group,moderate injury group and severe injury group were higher than those of the control group (P<0.05). The above index level of the severe injury group was higher than that of the moderate injury group and the mild injury group;the above index level of the moderate injury group was higher than that of the mild injury group,and the differences were statistically significant (P<0.05). Conclusion serum and urinary β2-microglobulin and high sensitivity C-reactive protein have certain clinical value in the diagnosis of diabetic nephropathy.[Key words] Serum and urinary β2-microglobulin;High sensitivity C-reactive protein;Diagnostic value糖尿病腎病(diabetic nephropathy,DN)属于糖尿病的并发症,临床上表现为三高(高血糖、高血压和高血脂)以及肾功能损伤,严重影响患者正常的生命活动,临床上很难根治,且致残率和致死率较高[1]。
超敏C-反应蛋白、血尿酸与不同危险分层急性非ST段抬高型冠脉综合征患者的相关性研究周祖勇;梁金花;周红辉【期刊名称】《中国当代医药》【年(卷),期】2016(023)019【摘要】目的:探讨血尿酸(SUA)和超敏C-反应蛋白(hs-CRP)与不同危险分层急性非ST段抬高型急性冠脉综合征(NSTEACS)的关系。
方法选取2013年6月~2015年6月我院收治确诊的NSTEACS患者78例作为观察组,其中NSTEACS 低危组24例,中危组27例,高危组27例。
选取我院同期住院排除冠心病的患者52例作为对照组。
所有患者在入院后第2天清晨采空腹静脉血或急诊冠状动脉造影术前采静脉血,检测各组患者SUA、hs-CRP水平。
结果SUA和hs-CRP水平随着NSTEACS患者危险分层的增高而升高。
两者在高危组中水平均最高;高、中危组SUA、hs-CRP水平与低危组及对照组比较,差异有统计学意义(P﹤0.05)。
低危组的SUA水平与对照组比较,差异有统计学意义(P﹤0.05)。
低危组的hs-CRP水平与对照组比较,差异无统计学意义(P﹥0.05)。
SUA和hs-CRP水平与不同危险分层NSTEACS呈正相关(r1=0.528、r2=0.446,P均﹤0.05)。
结论 SUA、hs-CRP水平与不同危险分层NSTEACS密切相关。
检测SUA、hs-CRP水平对不同危险分层NSTEACS患者病情程度评估有重要参考价值。
%Objective To investigate the relationship between serum uric acid (SUA),high-sensitive C-reactive protein (hs-CRP) and different risk stratification of patients with non-ST-elevation acute coronary syndrome (NSTEACS). Methods Altogether 78 cases of confirmed NSTEACS patients who had been treated in ourhospital from June 2013 to June 2015 were selected as observation group,including 24 cases in the low risk group,27 cases in middle risk group and 27 cases in high risk group.Meanwhile,52 cases of hospitalized patients with coronary heart diseases in the same period were selected as control group.Fasting venous blood was drawn from all the patients in the early morning of the 2nd day after their admission or before emergency coronary angiography for detection of SUA and hs-CRP levels in both groups.Results The level of SUA and hs-CRP increased in the higher risk stratification of NSTEACS patients,and was the highest in high risk group.The level of SUA and hs-CRP in both high and middle risk groups was significantly higher than that in low risk group and control group respectively (P﹤0.05).There was also significant difference in SUA level between low risk group and control group(P﹤0.05).Compared with that of control group,the level of hs-CRP in low risk group was higher but without significant difference between the two groups (P﹥0.05).SUA and hs-CRP levels were significantly positively correlated with different risk stratification of NSTEACS (r1=0.528,r2=0.446,P﹤0.05).Conclusion The levels of hs-CRP and SUA are closely related to the different risk stratification of NSTEACS patients.Therefore,the detection of SUA and hs-CRP levels in different risk stratification of NSTEACS patients has important reference signifi-cance in assessment of the patients'conditions.【总页数】3页(P50-52)【作者】周祖勇;梁金花;周红辉【作者单位】广东省鹤山市人民医院心内科,广东鹤山 529700;广东省鹤山市人民医院心内科,广东鹤山 529700;广东省鹤山市人民医院心内科,广东鹤山529700【正文语种】中文【中图分类】R541.4【相关文献】1.超敏C-反应蛋白测定对急性冠脉综合征危险分层意义 [J], 范标;季勇;张峰;王为群;姜黎晴2.超敏C-反应蛋白测定对急性冠脉综合征危险分层的意义 [J], 范标;季勇;张峰;王为群;姜黎晴3.血尿酸、超敏C-反应蛋白与急性冠脉综合征危险分层的关系研究 [J], 黎洁雯4.不同危险分层非ST段抬高急性冠脉综合征患者胱抑素-C和超敏C反应蛋白水平分析 [J], 周祖勇;梁金花;周红辉;周庆春5.血尿酸、超敏C-反应蛋白与急性脑梗死的相关性研究 [J], 周芹;徐红娣;陈冻伢因版权原因,仅展示原文概要,查看原文内容请购买。
血清超敏 C 反应蛋白、载脂蛋白 A1与2型糖尿病肾病的相关性探讨王海宁;李万顺;孙巨军【摘要】目的:探讨超敏 C 反应蛋白(hs‐CRP)及载脂蛋白 A1(ApoA1)与2型糖尿病肾病(DKD)发生及发展的相关性。
方法:147例2型糖尿病患者根据Mogensen 分期标准进行分组:单纯糖尿病组47例,早期 DKD 组58例,临床DKD 组42例,以40例健康体检者作为对照组,采用免疫透射比浊法测定ApoA1及hs‐CRP 水平,比较各组血清 ApoA1、hs‐CRP 、三酰甘油(TG)、肌酐(Cr)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL‐C)、低密度脂蛋白胆固醇(LDL‐C)水平,并分析血清ApoA1、hs‐CRP 水平与其他指标的相关性。
结果:早期 DKD 组及临床 DKD 组 ApoA1水平低于对照组及单纯糖尿病组(P<0.01),糖尿病各组hs‐CRP 、TG 、TC 、TC 、Cr 及LDL‐C 水平均明显高于对照组、HDL‐C 水平明显低于对照组(P<0.05、P<0.01);早期 DKD 组及临床 DKD 组hs‐CRP 、TG 水平均显著高于单纯糖尿病组,且临床 DKD 组ApoA1低于早期 DKD 组,hs‐CRP 及 Cr明显高于早期 DKD 组(P<0.05)。
2型糖尿病患者血清 ApoA1水平与HDL‐C 水平呈正相关(r =0.82,P<0.05),与尿白蛋白排出率呈负相关(r =-0.59,P<0.05);血清hs‐CRP 水平与患者体重指数、腰围、TG 水平及尿白蛋白排出率均呈正相关(r=0.51、0.39、0.33、0.46,P<0.05),与HDL‐C 水平呈负相关(r=-0.27,P<0.05)。
结论:检测2型糖尿病患者血清 ApoA1及hs‐CRP 水平可以敏感地反映患者早期肾功能损伤情况,有助于早期诊断DKD 并进行有效干预,以改善患者预后。
【期刊名称】《陕西医学杂志》【年(卷),期】2016(045)006【总页数】3页(P717-719)【关键词】糖尿病 ,2 型;糖尿病肾病/诊断 C-反应蛋白质/血液;载脂蛋白 A- Ⅰ /血液【作者】王海宁;李万顺;孙巨军【作者单位】西电集团医院西安710077;陕西省千阳县人民医院;西电集团医院西安710077【正文语种】中文【中图分类】R587.2主题词糖尿病, 2型糖尿病肾病/诊断 C-反应蛋白质/血液载脂蛋白A-Ⅰ/血液糖尿病肾病(Diabetic kidney disease,DKD)是糖尿病最常见的慢性微血管并发症之一,其病理表现以肾小球周边出现嗜酸性K-W结节为特征,临床表现为蛋白尿、水肿、高血压、贫血、进行性肾功能减退等,早期病情隐匿,是目前引起终末期肾病的主要原因之一[1],约10%~20%的糖尿病肾病最终发展成终末期肾病[2]。
25羟维生素D、超敏c反应蛋白、估计肾小球滤过率与脑萎缩相关性的临床研究黄晨岚【期刊名称】《黑龙江医药》【年(卷),期】2024(37)1【摘要】目的:探讨脑萎缩患者25羟维生素D、超敏c反应蛋白(hs-CRP)、估计肾小球滤过率检测意义及其对脑萎缩预测价值。
方法:回顾性分析脑萎缩的且年龄≥50岁的155例患者(观察组)与年龄≥50岁的134名健康体检人群(对照组)。
分别检测两组25羟维生素D、hs-CRP、肾小球滤过率,分析检测指标对脑萎缩的预测价值。
结果:观察组25羟维生素D、估计肾小球滤过率低于对照组,hs-CRP高于对照组(P<0.05)。
联合检测诊断脑萎缩的曲线下面积AUC优于三项指标单独检测(P<0.05)。
25羟维生素D、hs-CRP与估计肾小球滤过率联合检测诊断脑萎缩的效能高于三项指标单独检测(P<0.05)。
各指标均与脑萎缩呈密切相关(P<0.05)。
结论:25羟维生素D、估计肾小球滤过率、hs-CRP与中老年人脑萎缩发生发展相关,有一定预测性,临床针对上述指标进行联合检测可为脑萎缩的早发现早干预提供一定帮助。
【总页数】4页(P44-47)【作者】黄晨岚【作者单位】厦门弘爱医院【正文语种】中文【中图分类】R742.8【相关文献】1.2型糖尿病患者血清25羟维生素D3水平与高敏C反应蛋白、尿白蛋白排泄率的相关性研究2.糖化血红蛋白、超敏C-反应蛋白、胱抑素C、25-羟基维生素D 与2型糖尿病并发视网膜病变的相关性研究3.血清1,25-二羟维生素D3超敏C反应蛋白与2型糖尿病肾病的相关性研究4.血清1,25二羟维生素D 3联合超敏C反应蛋白水平对支气管肺炎患儿合并脓毒症的诊断效能5.血清25-羟维生素-D3 超敏C反应蛋白及心电图参数与ST段抬高型心肌梗死患者介入治疗后发生恶性心律失常的关系因版权原因,仅展示原文概要,查看原文内容请购买。
DOI:10.16658/ki.1672-4062.2023.15.058超敏C-反应蛋白(hs-CRP)与血脂检验在糖尿病新发患者中的应用价值研究陈蓉武警贵州总队医院内一科,贵州贵阳550002[摘要]目的分析超敏C反应蛋白(hypersensitive C-reactive protein, hs-CRP)与血脂检验在糖尿病新发患者中的应用价值。
方法选取2020年1月—2022年12月武警贵州总队医院内一科收治的糖尿病患者50例为观察组,另将同一时期收治的健康志愿者共50例作为对照组,比较两组血糖水平、hs-CRP与血脂高密度脂蛋白胆固醇(high density lipoprotein cholesterol, HDL-C)、低密度脂蛋白胆固醇(low density lipoprotein cholesterol, LDL-C)、三酰甘油(triacylglycerol, TG)以及血清总胆固醇(serum total cholesterol, TC),同时分析血糖与hs-CRP、血脂(HDL-C、LDL-C、TG、TC)相关性。
结果观察组血糖、hs-CRP与血脂水平优于对照组,差异有统计学意义(P<0.05);不同空腹血糖患者的hs-CRP与血脂水平比较,差异有统计学意义(P<0.05);患者血糖水平与血脂水平、hs-CRP均为正相关关联。
结论在糖尿病新发患者的临床检验中不仅可通过血糖观察疾病严重程度,同时还可利用hs-CRP与血脂评估患者的病情状态与疾病治疗效果,对临床诊断与治疗有重要意义。
[关键词] 超敏C反应蛋白;血脂;糖尿病;新发[中图分类号] R446.1 [文献标识码] A [文章编号] 1672-4062(2023)08(a)-0058-04Application Value of Hypersensitive C-reactive Protein (hs-CRP) and Blood Lipid Test in Newly Occurred Patients with DiabetesCHEN RongInternal Section One, Guizhou Armed Police Corps Hospital, Guiyang, Guizhou Province, 550002 China[Abstract] Objective To analyze the application value of hypersensitive C-reactive protein (hs-CRP) and blood lipid test in new occurred patients with diabetes.Methods A total of 50 newly diagnosed diabetes patients admitted to the Internal Section One of Guizhou Armed Police Corps Hospital in recent years from January 2020 to December 2022 were selected as the observation group, and a total of 50 healthy volunteers admitted during the same period were se⁃lected as the control group. The levels of blood glucose, hs-CRP, high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), triglyceride (TG) and serum total cholesterol (TC) were compared between the two groups. Analyzed the correlation between blood glucose and hs-CRP, blood lipids (HDL-C, LDL-C, TG, TC).Results The blood glucose, hs-CRP, and lipid levels in the observation group were better than those in the control group, and the difference was statistically significant (P<0.05). There was a statistically significant difference in hs-CRP and blood lipid levels among patients with different fasting blood glucose levels (P<0.05). Blood glucose level was positively correlated with blood lipid level and hs-CRP level.Conclusion In the clinical examination of new pa⁃tients with diabetes, not only the severity of the disease can be observed by blood sugar, but also the condition status and treatment effect of the disease can be evaluated by hs-CRP and blood lipid, which is of great significance for clinical diagnosis and treatment.[Key words] Hypersensitive C-reactive protein; Blood lipid; Diabetes mellitus; Newly occurred[作者简介]陈蓉(1975-),女,本科,副主任技师,研究方向为医学检验。
DOI:10.16658/ki.1672-4062.2023.03.030超敏C反应蛋白、尿微量白蛋白及全血糖化血红蛋白联合检测在早期糖尿病肾病中的应用价值桑璐,张思楠,张阳北京怀柔医院检验科,北京101400[摘要]目的探析早期糖尿病肾病患者诊断中,超敏C反应蛋白(hs-CRP)、尿微量白蛋白( UmAlb)、全全血糖化血红蛋白(HbA1c)的联合检测价值。
方法选取2021年1—12月于北京怀柔医院就诊的130例2型糖尿病患者为研究对象,按照尿白蛋白肌酐比值(UACR)分为UACR正常组(UACR<30 mg/g,65例)、UACR轻度增高组(30 mg/g≤UACR≤299 mg/g,65例)。
通过检测hs-CRP、HbA1c及UmAlb,探讨联合检测对早期糖尿病肾病的应用价值。
结果hs-CRP、UmAlb、HbA1c水平比较,UACR轻度增高组高于UACR正常组,差异有统计学意义(P<0.05)。
单独hs-CRP、UmAlb、HbA1c检测相比,早期糖尿病肾病准确率对比,差异无统计学意义(P> 0.05),联合3项指标检测早期糖尿病肾病的灵敏度、特异度、准确度均高于单独检测,差异有统计学意义(P< 0.05)。
结论早期糖尿病肾病患者诊断中,联合应用hs-CRP、UmAlb、HbA1c指标,可以为临床诊断和治疗提供相应的实验室依据,对早期糖尿病肾病患者的早期治疗和预后具有积极意义。
[关键词] 早期糖尿病肾病;尿微量白蛋白;超敏C反应蛋白;全血糖化血红蛋白[中图分类号] R587.2;R692.9 [文献标识码] A [文章编号] 1672-4062(2023)02(a)-0030-05Value of Combined Ultrasensitive C-reactive Protein, Urinary Microalbu⁃min and Alloglycosylated Hemoglobin in Early Diabetic NephropathySANG Lu, ZHANG Sinan, ZHANG YangDepartment of Laboratory, Huairou Hospital, Huairou, Beijing, 101400 China[Abstract] Objective To explore the joint detection value of hypersensitive C-reactive protein (hs-CRP), urinary mi‐croglobulin (UmAlb) and glycosylated hemoglobin A 1c (HbA1c) in the diagnosis of early diabetic nephropathy.Methods 130 patients with type 2 diabetes mellitus who attended Huairou Hospital in Beijing from January to Decem‐ber 2021 were selected for the study. According to urinary albumin creatinine ratio (UACR), they were divided into normal UACR group (UACR <30 mg/g, 65 cases) and mildly increased UACR group (30 mg/g≤UACR≤299 mg/g, 65 cases); hs-CRP, HbA1c and UmAlb were measured; the application value of the combined test for early diabetic ne‐phropathy was explored. Results hs-CRP, UmAlb, and HbA1c levels were higher in the group with mildly increased UACR than in the group with normal UACR, the difference was statistically significant (P<0.05). There was no statisti‐cally significant difference in the accuracy of early diabetic nephropathy compared with hs-CRP, UmAlb, and HbA1c testing alone (P>0.05); the sensitivity, specificity, and accuracy of the combined three indexes for detecting early dia‐betic nephropathy were higher than those of the individual tests, the difference was statistically significant (P<0.05).Conclusion The combined application of hs-CRP, UmAlb, and HbA1c indexes in the diagnosis of patients with early diabetic nephropathy can provide the corresponding laboratory basis for clinical diagnosis and treatment, which has positive significance for the early treatment and prognosis of early diabetic nephropathy patients.[Key words] Early diabetic nephropathy; Urinary microalbumin; Hypersensitive C-reactive protein; Glycosylated he‐moglobin A1c[作者简介]桑璐(1991-),女,硕士,初级检验师,研究方向为血液检验。
超敏C-反应蛋白与2型糖尿病肾病的关系尤巧英;李成江;朱麒钱;斯徐伟【期刊名称】《医师进修杂志》【年(卷),期】2005(028)005【摘要】目的探讨C-反应蛋白(CRP)与不同时期糖尿病肾病的关系。
方法采用颗粒增强免疫法测定超敏CRP(usCRP)。
根据尿白蛋白排泄率(UAER)将104例2型糖尿病患者分为正常蛋白尿组(48例)、微量白蛋白尿组(30例)、临床蛋白尿组(26例)。
另选30例作为正常对照组。
观察各组血清usCRP水平。
结果2型糖尿病各组血清usCRP水平较正常对照组明显升高,且usCRP水平随白蛋白尿的增加而升高;在2型糖尿病病人中,Person相关分析显示usCRP与UAER(r=0.607,P=0.000)、甘油三酯(r=0.423,P=0.002)及血肌酐(r=0.322,P=0.019)呈正相关,逐步线性回归结果表明,UAER、甘油三酯是影响usCRP的主要因素。
结论CRP与糖尿病肾病有关,且其水平与糖尿病肾病的程度呈一致性。
【总页数】3页(P24-26)【作者】尤巧英;李成江;朱麒钱;斯徐伟【作者单位】绍兴市人民医院内分泌科312000;浙江大学医学院附属第一医院内分泌科【正文语种】中文【中图分类】R541.4【相关文献】1.2型糖尿病肾病患者血清超敏C-反应蛋白与尿白蛋白排泄率相关性研究 [J], 陆晓梅2.血清超敏C-反应蛋白和白细胞介素-6与2型糖尿病肾病的关系 [J], 邹晓清;粟文堂3.农村2型糖尿病患者超敏 C-反应蛋白与糖尿病肾病的相关性分析 [J], 赵耀华4.超敏C-反应蛋白与2型糖尿病肾病的关系 [J], 尤巧英; 李成江; 朱麒钱; 斯徐伟5.农村2型糖尿病患者超敏C-反应蛋白与糖尿病肾病的相关性分析 [J], 赵耀华因版权原因,仅展示原文概要,查看原文内容请购买。
超敏C反应蛋白、血尿酸与青年高血压的相关性分析刘艳丽;王晶【摘要】目的探讨超敏C反应蛋白(hs-CRP)、血尿酸(UA)与青年高血压(EH)患者的相关性.方法选取2016年1月-2017年1月我院收治的青年EH患者70例为观察组,其中Ⅰ级37例,Ⅱ级18例,Ⅲ级15例,另选取同期体检健康者70例为对照组.两组对象均采集清晨空腹静脉血,采用全自动血生化分析仪测定血脂水平,采用尿酸酶-过氧化物酶法测定UA,免疫比浊法测定hs-CRP,观察高血压不同分级UA、hs-CRP水平变化.结果观察组患者总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、UA、hs-CRP水平均高于对照组,高密度脂蛋白胆固醇(HDL-C)水平低于对照组(P均<0.05);且随高血压级别的升高,UA、hs-CRP水平逐渐上升(P<0.05);观察组血清UA与hs-CRP呈正相关性(r=0.758,P<0.05).结论 UA、hs-CRP与青年MH的发生、发展具有相关性,因此建议将UA、hs-CRP作为青年高血压患者常规检查,以便早进行干预,减少严重心脑血管并发症的发生.【期刊名称】《宁夏医科大学学报》【年(卷),期】2017(039)008【总页数】3页(P934-936)【关键词】超敏C反应蛋白;血尿酸;青年高血压;相关性【作者】刘艳丽;王晶【作者单位】河北省唐山市协和医院,唐山 063004;河北省唐山市协和医院,唐山063004【正文语种】中文【中图分类】R544.1随着人们生活水平的提高及膳食、行为方式的改变,近年原发性高血压病(EH)有逐年上升、并向年轻化发展趋势,使青年EH患者逐年增多[1]。
研究证实[2],EH存在明确的血管壁炎症反应,超敏C反应蛋白(hs-CRP)作为炎性标志物之一,被认为在心血管事件中起重要作用[3]。
尿酸为人体内核酸代谢的最终产物,研究显示[4],高尿酸血症是EH、心血管疾病、糖尿病、肾脏疾病的重要危险因素和预后因素。