宫颈鳞癌年轻患者LOT术后卵巢内分泌功能和并发症情况分析邬 琳（西电集团医院妇产科，西安 710077）【摘要】目的：探讨宫颈鳞癌年轻女性行宫颈癌手术治疗时同时行卵巢位移术（LOT）对患者的卵巢内分泌功能影响及并发症的发生情况。
方法：对本院妇科2011年7月～2013年7月收治的88年轻宫颈鳞癌妇女的临床及术后随访资料进行回顾性分析，根据是否进行LOT手术及接受术后放疗进行分层分析比较患者的激素水平及并发症的发生情况。
结果：术前LOT组和非LOT组的FSH、LH、E2、Kupperman评分值比较差异均不具有统计学意义；不放疗的患者，LOT和非LOT患者的卵巢功能指标（FSH、LH、E2、Kupperman评分）差异不显著，放疗的患者LOT 组的卵巢功能指标（FSH、LH、E2、Kupperman评分）优于非LOT组；不放疗组的LOT组、非LOT组的卵巢功能指标（FSH、LH、E2、Kupperman评分）均优于放疗组的LOT组、非LOT组。
对于LOT手术的患者，放疗患者的卵巢功能正常率72.73%与未放疗患者的96.67%差异不具有统计学意义；非LOT组患者中，放疗患者的卵巢功能减退率100%显著高于未放疗患者的5.56%。
LOT手术的52例患者中，术后复查B超发现有1例患者盆腔积液，1例患者术后异位卵巢部位疼痛，非LOT组仅1例出现盆腔积液；两组术后并发症比较差异不显著。
结论：对于术后进行放疗治疗的患者，LOT手术可以有效对卵巢进行保护，但仍然受到射线的伤害。
如果术后不进行放疗治疗，则患者的卵巢功能基本不受影响。
【关键词】宫颈鳞癌；宫颈癌手术；卵巢位移术；内分泌功能；并发症【中图分类号】R737.33 【文献标识码】A 【文章编号】1673-016X（2016）04-0080-04Analysis of cervical squamous cell carcinoma in young patients with LOT after ovarianendocrine function and complicationsWu Lin(Xi’an XD GroupHospital, Xian 710077, China)[Abstract] Objective Study of cervical squamous cell carcinoma in young women for cervical cancer operation treatment and ovarian displacement operation(LOT)impact on patients with ovarian endocrine function and complications. Methods On the 2011 July to 2013 July in Department of gynecology were 88 young women cervical squamous cell carcinoma and clinical follow-up data were retrospectively analyzed, occur according to whether LOT operation and received postoperative radio-therapy were stratified analysis of hormone levels and complications were compared between the patients condition. Results Pr-eoperative LOT group and non LOT group of FSH, LH, E2, Kupperman scores were not statistically significant; no radiotherapy patients, ovarian function indexes of LOT and non LOT patients(FSH, LH, E2, Kupperman score)did not show significant dif-ference, index of ovarian function in radiotherapy patients in group LOT(FSH, LH, E2, Kupperman score)is better than that of the non LOT group; ovarian function index of LOT group, non LOT group is not in the radiation group(FSH, LH, E2, Kupperman score)were LOT group, non LOT group than those in the radiation group. For the LOT operation of the patients, 96.67% normal ovarian function difference rate of radiotherapy in patients with and without radiotherapy in 72.73% patients was not statistically significant; non LOT group, the ovary function of radiotherapy in patients with the decreasing rate of 100% was significantly higher than non patients in radiotherapy 5.56%.52 cases of LOT patients in operation, postoperative examination B ultrasound found 1 cases of patients with pelvic effusion, 1 cases of patients with postoperative ectopic ovarian site pain, non LOT group, only 1 cases had pelvic effusion; postoperative complications of two groups there was no significant difference. Conclusion For postoperative radiotherapy in the treatment of patients, LOT surgery can effectively protect the ovary, but still subject to radia-tion. If not for the postoperative radiation therapy, then the patients with ovarian function is basically not affected.[Key words] cervical squamous cell carcinomas; cervical cancer surgery; ovary displacement technique; endocrine func-tion; complications收稿日期： 2016-03-02通讯作者：邬琳，E-mail: wulin_5515@ 现如今，宫颈鳞癌变率日益增高，患者人数越来越多，发病者年龄呈现年轻化趋势，已严重损害广大女性的生命健康安全，影响到她们的家庭生活幸福［1］。
