l-lumbar-fusion-a-prospective-cohort-study-with-a-minimum-five-year-follow-up-Anandjiwal

- 10 -Chinese and Foreign Medical Research Vol.20, No.30 October, 2022论 著 Lunzhu 《中外医学研究》第20卷 第30期（总第542期）2022年10月

*基金项目：安徽省蚌埠医学院自然重点项目（2020byzd088）①蚌埠医学院第一附属医院　安徽　蚌埠　233004药物涂层球囊治疗下肢动脉硬化闭塞症短期效果分析*

蔡瑶①　余朝文①　官泽宇① 【摘要】　目的：观察紫杉醇药物涂层球囊治疗下肢动脉硬化闭塞症的短期效果。方法：选取蚌埠医学院第一附属医院血管外科2018年1月-2020年9月104例初发症状性下肢动脉硬化闭塞症的患者，根据治疗方法分为试验组和对照组，每组52例。试验组给予紫杉醇药物涂层球囊进行血管成形术，对照组给予血管裸金属支架植入术。对手术前后不同阶段两组Rutherford分级、患肢踝肱指数（ABI）、跛行距离、一期通畅率、再狭窄率和不良事件的发生进行分析。结果：两组术前、术后6个月Rutherford分级比较，差异均无统计学意义（P>0.05）；但术后6个月，两组Rutherford分级较术前均改善，差异均有统计学意义（P<0.05）。两组术前、术后1周及术后1个月间歇性跛行距离比较，差异均无统计学意义（P>0.05）；两组手术前后不同时间点间歇性跛行距离组内比较，差异均有统计学意义（P<0.05）。两组术前、术后1周及术后1个月ABI比较，差异均无统计学意义（P>0.05）；但试验组术后6个月ABI高于对照组（P<0.05）；两组手术前后不同时间点ABI组内比较，差异均有统计学意义（P<0.05）。两组术后6个月一期通畅率比较，差异无统计学意义（P>0.05）；两组术后6个月再狭窄率比较，差异有统计学意义（P<0.05）。在随访过程中，两组各有1例患者死亡，直接原因为急性心脑血管意外；两组均未发生截肢。结论：紫杉醇药物涂层球囊治疗下肢动脉硬化闭塞症的短期效果与裸金属支架相当，但术后6个月ABI的值更高、再狭窄率更低。 【关键词】　下肢动脉硬化闭塞症　药物涂层球囊　短期疗效 doi：10.14033/ki.cfmr.2022.30.003 文献标识码　A 文章编号　1674-6805（2022）30-0010-05 Analysis of Short-term Efficacy of Drug-coated Balloon in the Treatment of Lower Extremity Arteriosclerosis Obliterans/CAI Yao, YU Chaowen, GUAN Zeyu. //Chinese and Foreign Medical Research, 2022, 20(30): 10-14 [Abstract]　Objective: To investigate the short-term efficacy of Paclitaxel drug-coated balloon in the treatment of lower extremity arteriosclerosis obliterans. Method: A total of 104 patients with initial symptomatic lower extremity arteriosclerosis obliterans in the First Affiliated Hospital of Bengbu Medical College from January 2018 to September 2020 were selected and divided into the experimental group and the control group according to treatment method, 52 cases in each group. The experimental group was given Paclitaxel drug-coated balloon dilatation and the control group was given vascular bare-metal stent implantation. The Rutherford grade, ankle-humeral index (ABI), intermittent claudication distance, primary patency rate, restenosis rate and incidence of adverse events were compared between two groups in different stages before and after surgery. Result: The differences between two groups in Rutherford grading before and 6 months after surgery were not statistically significant (P>0.05); however, the Rutherford grading of two groups at 6 months after surgery were improved compared with those before surgery, the differences were statistically significant (P<0.05). The differences between two groups in intermittent claudication distance before, 1 week and 1 month after surgery were not statistically significant (P>0.05); there were statistically significant differences in the distance of intermittent claudication between the two groups at different time points before and after operation (P<0.05). The differences between two groups in ABI before, 1 week and 1 month after surgery were not statistically significant (P>0.05); but ABI in the experiment group at 6 months after surgery was higher than that in the control group (P<0.05); there were statistically significant differences in ABI between the two groups at different time points before and after operation (P<0.05). The difference between two groups in first-stage patency at 6 months after surgery was not statistically significant (P>0.05); the difference between two groups in restenosis rate at 6 months after surgery were statistically significant (P<0.05). During follow-up, 1 patient died in each group, and the direct cause was acute cardio-cerebrovascular accident, no amputation occurred in two group. Conclusion: The short-term effect of Paclitaxel drug-coated balloon dilatation is comparable to that of bare-metal stent, but ABI is higher and restenosis rate is lower after 6 months. [Key words]　Lower extremity arteriosclerosis obliterans　Drug-coated balloon　Short-term efficacy First-author’s address: The First Affiliated Hospital of Bengbu Medical College, Bengbu 233004, China

80J Clin Neuosura,Febtarf 2021 ,Voi. 18,No. 1

DOI：10-3969/j. ien-1672-770. 2021.01.017 •临床研究-

神经内镜微创术结合LCFD术对高血压脑出血患者症状、预后

及影响术后生活质量的Logistics分析

刘胜华，周政，唐协林,黎乾科，刘怡东，赵超，肖奎，羊飞龙,何绍勇，罗静，夏湘平，叶勇强

!摘要】目的 研究神经内镜微创术结合腰大池持续引流（LCFD）术治疗高血压脑出血（HICH）的预后

及其影响因素。方法66例HICH患者随机分为观察组及对照组，每组33例。观察组患者采用神经内镜微

创术结合LCFD治疗，对照组患者采用标准骨瓣开颅血肿清除术结合LCFD治疗。比较两组患者的手术相关

指标，以及手术前后格拉斯哥昏迷量表（GCS）评分、格拉斯哥预后量表（GOS）评分、日常生活活动能力（ADL）

评分、Epwoth嗜睡量表（ESS）评分和预后生活质量SF-6评分;分析影响术后预后的因素。结果 观察组患

者的手术时间及术中出血量显著低于对照组，血肿清除率显著高于对照组;术后的GCS、GOS、ADL、ESS评分

及SF-6评分显著高于对照组（均P <0.001）。多因素分析显示，与子女同住、吸烟、饮酒、脑出血量、脑中线

移位、脑出血到手术时间、破入脑室为脑出血预后的独立影响因素。结论 神经内镜微创术结合LCFD对 HICH具有较好的疗效，患者的预后较好。同时应及时对患者是否与子女同住、吸烟、饮酒及脑出血量、脑中

线移位、脑出血到手术时间、破入脑室进行了解与监测（并早期开展康复治疗干预$

!关键词】 高血压脑出血；神经内镜微创术（腰大池持续引流；预后；影响因素!中图分类号】R651；R743.2 【文献标志码】B 【文章编号】1672-770（2021 %01异080-5

Logistics analysis on effect of neuroendoscopic minimally invasive surgery combined with LCFD on the

退变性颈椎病前路手术治疗进展

宋祖坤;陈旭狮;张嘉伟;桑朝辉;孟湛东;江建明

【摘 要】退变性颈椎病是临床常见病、多发病之一,发病年龄呈现年轻化趋势.自Robinson和Smith首创颈椎前路减压植骨融合术以来,前路手术已成为治疗脊髓腹侧压迫所致颈椎病的主流术式.该文对颈椎前路减压融合术、非融合术(人工颈椎间盘置换)、混合术及微创手术的研究进展进行综述,旨在为退变性颈椎病的术式选择提供参考.

【期刊名称】《中国骨科临床与基础研究杂志》

【年(卷),期】2017(009)002

【总页数】9页(P113-121)

【关键词】退变性颈椎病;前路手术;减压术,外科;骨移植;脊柱融合术;椎间盘;关节成形术,置换;混合术;外科手术,微创性

【作 者】宋祖坤;陈旭狮;张嘉伟;桑朝辉;孟湛东;江建明

【作者单位】510515 广州,南方医科大学南方医院脊柱骨科;510515 广州,南方医科大学南方医院脊柱骨科;510515 广州,南方医科大学南方医院脊柱骨科;510515

广州,南方医科大学南方医院脊柱骨科;510515 广州,南方医科大学南方医院脊柱骨科;510515 广州,南方医科大学南方医院脊柱骨科

【正文语种】中 文

【中图分类】R681.531;R687 退变性颈椎病是成人颈脊髓损害的常见原因。对于症状严重或呈进行性加重、3～6个月正规保守治疗无效的患者可施行手术治疗，以尽早对受压脊髓、神经根及血管彻底减压，重建颈椎稳定性及生理弯曲，最大程度地恢复脊髓功能。常见的手术入路包括前路、后路及前后联合入路，入路选择主要根据脊髓压迫来源及位置、受累节段数、颈椎稳定性等综合考虑而定[1-2]。其中颈椎前路手术临床应用较为广泛，主要适用于存在局限性颈椎管狭窄且压迫主要来自腹侧者，特别是对于伴有颈椎不稳的患者，前路融合手术可以起到恢复生理弯曲及稳定颈椎的作用。本文就颈椎前路减压融合术、非融合术（人工颈椎间盘置换）、混合术及微创手术研究进展进行综述。

WORD格式

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脊柱外科常用英语词汇

LUMBARSPINE

Lumbardischerniationsyndrome腰椎间盘突出症

FenestrationandDiscectomyLovemethod(开窗髓核摘除术Love法)minimallyinvasivediscectomy微创椎间盘切除术MED(micro-endoscopicdiscectomy)内镜椎间盘切除术

Burst（Compression）fractureofT1-12,L1-5胸腰椎爆裂(压缩)骨折Openreductionandpediclescrewinternalfixation切开复位椎弓根螺钉内固定Decompressionandpediclescrewsysteminternalfixationwithbonegraft减压植骨椎弓根钉内固定

Lumbarspinecanalstenosis腰椎管狭窄症spinalstenosisFenestrationdecompression(开窗减压)laminectomy椎板切除术

Degenerativespondylolisthesis假性（退变性）脊柱滑脱

Spondyloliticspondylolisthesis真性（峡部裂性）滑脱

Reductionandinterbodyfusion(复位椎间植骨融合)

anteriorapproach前入路

posteriorapproach后入路

Removalofinternalfixation内固定取出术

ALIF：anteriorlumberinterbodyfusion前路椎间融合

PLIF：posteriorlumbarinterbodyfusion后路椎间融合

TLIF：transforaminallumbarinterbodyfusion经椎间孔融合