生理学复习题 名词解释 英文版Human Physiology

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Human Physiology Physiology is one of the biological sciences dealing with normal life phenomena of all living organisms.

Human Physiology Human Physiology (人体生理学) is one of the biological sciences dealing with normal life phenomena of human being.

Internal Environment Extracellular fluid directly baths body cells Internal environment = Extracellular fluid

Homeostasis ( 稳态) Homeostasis means a condition in which physical and chemical properties of internal environment is kept at a “dynamic constancy”.

Regulation- the ability of an organism to maintain a stable internal conditions in a constantly changing environment

Nervous Regulation a process in which body functions are controlled by the nerve system. Pathway: nerve reflex Structure basis: reflex arc Types: unconditioned reflex and conditioned reflex

Hormonal Regulation a regulatory process performed by hormones or active chemical substances in blood or tissue.

Auto-regulation direct response of the organ to stimulus, independent of nervous and hormonal control.

Feedback Control System反馈控制系统 a process in which a part of output (feedback signal) from controlled organ returns to affect or modify the action of the control system. closed loop system very important control system

Negative feedback If the feedback signals produce effect opposite to action of control system, this type of feedback is called negative feedback.

Positive feedbackIf the feedback signals from controlled system increase the action of the control system, this type of feedback is called positive feedback. Feed-Forward Control a direct effect of stimulus (interference or disturbance signal 干扰信号) on control system before action of the feedback signal occurs

Fluid Mosaic Model( 液态镶嵌模型) Fluid:To be able to flow freely as gases or liquids. Mosaic: a special material that can be inlaid into a picture or patchwork. Cell membrane consists of a double layer of lipid molecules ( lipid bilayer ) , in which globular protein molecules are inlaid.

Simple Diffusion a random thermal movement of the substances across membrane down concentration gradient Substances: O2 CO2 N2 H2 steroids fatty acid alcohol H2O

Facilitated Diffusion a diffusion process of lipid insoluble or water soluble substances across cell membrane down their concentration or potential gradients by aid of membrane proteins. Substances: ions: K+ Na+ Ca2+ glucose, amino acid, urea

Primary Active Transport It is a process, in which the membrane moves substances uphill against their chemical or electrical gradients by directly expending energy (ATP). Substances: ions: Na+, K+, Ca2+, Cl-, H+ , I- etc. Mechanism: ion pump /ATPase (离子泵/ATP酶)

Secondary Active Transport / cotransport It is one of the active transports,in which process the expending energy is supplied indirectly from ATP. Substances: glucose, amino acid, Ca2+, H+ etc. Mechanism: symporter→symport, antiporter or exchanger→antiport Examples: Na+ - Glucose symporter, Na+-Ca2+ exchanger

Phagocytosis : “cellular eating” (吞噬) cell engulfs a particle and packages it with a food vacuole.

Pinocytosis : ”cellular drinking” (胞饮)cell gulps droplets of fluid by forming tiny vesicles. (unspecific) including fluid-phase endocytosis and receptor-mediated endocytosis

Resting Potential (RP) It is an electrical potential difference across cell membrane in a resting cell

Polarization ( -70 mV, A) (极化 )It is a state in which membrane is negative inside and positive outside at rest. Depolarization ( A to B ) (去极化) Membrane potential becomes less negative than resting level.

Hyperpolarization ( A to C ) (超极化) Membrane potential becomes more negative than resting level.

Repolarization ( B to A ) (复极化)restoration of polarization state

Reverspolarization ( B to D )(反极化) reversal of polarization

Action Potential a rapid, reversible and conductive change in membrane potential after cell is stimulated.

Threshold / threshold intensity: It is the minimal or smallest intensity of stimulus to induce action potential when its wave and duration are fixed.

Threshold potential It is a critical membrane potential level at which an action potential can occur. Value: ﹤15 - 20 mV How to reach it Threshold stimulus depolarizes the membrane to this level.

local response: a small local change in membrane potential caused by a subthreshold stimulus. Excitation: The process of the cell to generate the action potential Excitability: The ability of the cell to generate the action potential Excitable cells: Cells that generate action potential during stimulus. in excitable cells (muscle, nerve, secretery cells), the action potential is the marker of excitation.