・临床论著・介入治疗急性髂股静脉血栓董典宁 张十一 金 星 吴学君 种振岳 张精勇 孙 岩 侯向前(山东省立医院血管外科,济南 250021) 【摘要】 目的 探讨介入治疗急性髂股静脉血栓的临床疗效。
方法 2004年2月～2006年4月对20例急性髂股静脉血栓采用超声引导下腘静脉置管溶栓联合髂静脉支架植入治疗,静脉造影评价静脉通畅程度。
结果 20例均在超声引导下腘静脉置管溶栓;15例行球囊扩张及髂静脉支架术,5例行单纯球囊扩张术;10例行临时性下腔静脉滤器置入术。
腘静脉置管溶栓后经导管静脉造影见髂静脉再通率30%～90%,平均55%;股静脉再通率40%～80%,平均65%。
1例术后出现血尿,未发现症状性肺动脉栓塞。
术后患肢临床症状明显减轻或消失。
住院费用(5.2～8.1)万元,平均7.4万元。
20例随访1～24个月,平均12个月,15例髂静脉支架植入髂静脉通畅率100%(15/15),5例髂静脉球囊扩张中,2例髂静脉完全闭塞,3例髂静脉再通10%～20%。
结论 腘静脉置管溶栓术联合髂静脉支架植入术是治疗急性髂股静脉血栓的有效方法之一,但是价格昂贵,广泛应用有一定困难。
【关键词】 深静脉血栓形成; 髂股静脉; 溶栓; 支架 中图分类号:R654.3;R543.3 文献标识:A 文章编号:1009-6604(2007)07-0609-03I n terven ti ona l therapy for acute ili ofe m ora l venous thro m bosis D ong D ianning,Zhang Shiyi,J in X ing,et al.D epart m ent of V ascular Surgery,Shandong P rovincial Hospital,J inan250021,China【Abstract】 O bjecti ve To investigate the clinical effect of interventi onal therapy in the treat m ent of acute ili ofe moral venous thr o mbosis. M ethods A t otal of20patients with acute ili ofe moral venous thr ombosis was treated by interventi onal therapy fr om February2004t o Ap ril2006.Under the guidance of ultras onography,intravenous thr ombolysis thr ough the pop liteal vein combined with iliac vein stenting was e mp l oyed.The venous patency was assessed with angi ography. Results The catheter2based thr ombolysis thr ough the i p silateral pop liteal vein was effective f or all the patients.Ball oon dilatati on angi op lasty combined with endovascular stenting was app lied in15patients,while ball oon dilatati on angi op lasty al one was utilized in other5patients.The i m p lantati on of a te mporary cava filter was required in10patients.After intravenous thr ombolysis thr ough the pop liteal vein,the recanalizati on rate was 30%～90%(mean,55%)in the iliac vein and40%～80%(mean,65%)in the fe moral vein.Post operative hematuria was encountered in1patient.No sy mp t omatic embolis m of pul m onary artery was seen.Post operatively,clinical sy mp t om s on the effected li m b significantly subsided or comp letely disappeared.The hos p italizati on expenditure was52000～81000yuan(mean,74000 yuan).Foll ow2up observati ons f or1～24months(mean,12months)were carried out in the20patients.The patency rate was100% (15/15)in15patients receiving iliac vein stenting.Out of5patients with ball oon dilatati on,the iliac vein was comp letely obstructed in2patients and was recanalized by10%～20%in3patients. Conclusi on s Catheter2based thr ombolysis thr ough the pop liteal vein combined with endovascular stenting is an effective therapeutic strategy f or acute ili ofe moral venous thr ombosis,but it is very expensive.【Key W ords】 Deep venous thr ombosis; Ili ofe moral vein; Thr o mbolysis; Stent 深静脉血栓形成(deep venous thr ombosis,DVT)的发病率逐年增加,急性期可以合并致死性肺动脉栓塞(pul m onary thr omboe mbolis m,PE),远期可以出现血栓形成后遗症(postthr omobosis syndr ome,PTS)。
