OPTIMAX实验平台

化学鸟住够3終2021,Chemistry&Bioengineering-------------------------------------------------------H发画用doi：10.3969/j.issn.1672—5425.2021.03.010马志弟，胡晓敏，李晓露，等.伊维菌素制备工艺研究[J].化学与生物工程,2021,38(3):51-54.MA Z J,HU X M,LI X L,et al.Preparation process of Ivermectin]J].Chemistry&Bioengineering,2021,38(3):51-54.伊维菌素制备工艺研究马志,胡晓敏时，李晓露1,高月麒1,任风芝“，张雪霞“(1.华北制药集团新药研究开发有限责任公司微生物药物国家工程研究中心河北省工业微生物代谢工程技术研究中心，河北石家庄050015；2.华北制药集团爱诺有限公司，河北石家庄052165)摘要：以阿维菌素为原料、甲苯为溶剂，通过催化加氢反应得到伊维菌素粗粉，再通过重结聶纯化得到伊维菌素精粉，并优化了阿维菌素加氢反应条件及伊维菌素粗粉纯化工艺。

确定阿维菌素加氢反应条件为：料液比1：(3〜5)(g：mL)、催化剂用量1.0%〜1.5%；再通过控制晶种粒度和梯度降温过程，有效改善了晶体外观和产品质量，所得伊维菌素精粉纯度大于99%,质量符合USP标准。

该工艺简洁高效、质量可控，适用于伊维菌素的工业化生产。

关键词：阿维菌素；加氢反应；催化剂；结晶；伊维菌素中图分类号:TQ453.299文献标识码：A文章编号：1672-5425(2021)03-0051-04Preparation Process of IvermectinMA Zhijun1,HU Xiaomin2*,LI Xiaolu1,GAO Yueqi1,REN Fengzhi1*,ZHANG Xuexia1*(1.NCPC New Drug Research&Development Co.,Ltd.,National Engineering Research Centerof Microbial Medicine, Hebei Industry Microbial Metabolic Engineering&Technology Research Center, Shijiazhuang050015?China;2.NCPC Aino Co.Ltd*9Shijiazhuang052165^China) Abstract:U sing Avermectin as a raw material and toluene as a solvent,we obtained crude Ivermectin pow­der by a catalytic hydrogenation reaction,and then obtained refined Ivermectin powder by recrystallization puri­fication.Moreover,we optimized the hydrogenation reaction conditions of Avermectin and purification process of crude Ivermectin powder・The hydrogenation reaction conditions of Avermectin can be determined as follows：the solid-liquid ratio of1!(3—5)(g!mL),and the catalyst dosage of1・0%—1.5%・By controlling the seed crystal size and the gradient cooling process?the crystal appearance and product quality are improved effective­ly,and the purity of the refined Ivermectin powder is more than99%，the quality meets the USP standard.The process is simple and efficient and the quality can be controlled,which is suitable for the industrial production of Ivermectin.Keywords:Avermectin；hydrogenation reaction；catalyst；crystallization；Ivermectin伊维菌素为阿维菌素的衍生物，属半合成的广谱抗寄生虫药，对体内外寄生虫特别是线虫和节肢动物均有良好驱杀作用。

同步辐射光源实验平台的建设与应用随着科技的飞速发展，同步辐射光源技术也日益成为了现代科学研究中的重要工具之一。

同步辐射光源可以产生高亮度、高强度的光束，以及广泛的光谱范围，不仅可以研究物质的结构、性质、动力学等方面，还可以应用于医学、环境保护、甚至是文化遗产保护等方面。

为了更好地发挥同步辐射光源的作用，各国纷纷建设同步辐射光源实验平台，通过共享设备和资源，促进科研合作和创新。

本文将从同步辐射光源实验平台的建设和应用两方面进行阐述。

一、同步辐射光源实验平台的建设同步辐射光源实验平台一般由光源设备、探测系统、样品制备设备、计算软件等组成。

其中，光源设备是整个平台中最为核心和重要的部分，其质量和性能直接影响到实验结果的可靠性和精度。

目前世界上主要的同步辐射光源实验平台有美国的APS、德国的DESY、英国的Diamond等。

我国的同步辐射光源实验平台建设起步较晚，但近年来发展迅速。

目前国内已经建成的同步辐射光源有北京的BSRF、上海的SSRF、合肥的NSRL等。

其中，SSRF是目前国内最先进的大型同步辐射光源，具有光束光度高、辐射出的光子能量范围广、低噪音等突出的特点。

为了更好地利用SSRF的高质量光束，提高实验效率和水平，建设同步辐射光源实验平台成为了迫切需要，我国各大高校、科研机构等纷纷加快了建设步伐。

具体而言，同步辐射光源实验平台的建设与应用涉及到多个领域和专业，因此需要进行多学科的协作和交流。

例如，在光学领域，需要采用高精度的反射镜、晶体、透镜等完善光学系统；在控制与电子学领域，需要开发高精度控制和数据处理技术，以保证实验的可重复性和一致性；在计算机科学领域，需要研发高效的数据处理和计算软件等。

只有各方协作和密切配合，才能建设出高质量的同步辐射光源实验平台，为科研事业做出更大的贡献。

二、同步辐射光源实验平台的应用同步辐射光源实验平台具有强大的光束和丰富的光谱范围，因此广泛应用于材料科学、生物科学、环境保护、文化遗产保护等领域。

目录重要安全信息 — 第 1 部分 4系统拆封 — 第 2 部分 62.1 其他选配件 7安装 — 第 3 部分 83.1 拆除现有平台 83.2 安装 OptiScan III 平台 83.3 线缆连接 93.4 聚焦驱动安装 10入门 — 第 4 部分 124.1 USB 操作 124.2 使用控制杆 (CS152DP) 13高级操作 — 第 5 部分 155.1 RS232 命令集 155.2 MACRO 和 SOAK 155.3 SOAK 命令 175.4 OPTISCAN III 和 OPTISCAN II 之间的区别 185.5 常用命令 195.6 平台命令 225.7 Z 轴命令 245.8 图案命令 265.9 Z 错误代码 275.10 CS152DP（控制杆配置） 28故障排除 — 第 6 部分 30系统规格 — 第 7 部分 33 返厂和维修 — 第 8 部分 35附录 — 第 9 部分 36A) 非标准聚焦驱动安装 36B) LEICA DML 系列 H122BL 聚焦设备安装 41C) Leica DML 和 DMR 系列直接联轴节聚焦设备安装 45D) PRIOR TERMINAL 运行说明49E) 兼容 OPTISCAN III 52F) 面向中国客户的相关信息诚挚感谢您选用 OptiScan III 系统，我们期望它实用、可靠，能够有效帮助您完成显微镜检查相关工作。

请在安装和使用系统前务必花时间仔细阅读本手册。

本手册包含重要的安全信息，以及如何正确安装和操作产品以避免损坏的相关建议。

如果您对本产品有任何疑问或问题，请随时联系 Prior。

重要安全信息第 1 部分•本手册包含重要的安全信息和操作说明，请务必妥善保管。

•使用时务必遵照操作说明，否则设备自带的防护可能会遭损坏。

•使用平台系统前，请遵照机身上以及本手册中的所有警告、安全和操作说明。

•本产品的安全操作室温为 5-40°C，相对湿度为 80%。

VisuMax from ZEISSDefining the pulse rate in refractive surgeryAccelerating the pulse rate of your practice. ZEISS VisuMax// PRECISIONMADE BY ZEISSRemarkable precision and detailDefining new trends in modern corneal surgeryAs a ground-breaking, high-performance femtosecond laser system, theVisuMax® from ZEISS is significantly shaping the world of refractive surgery.With its cutting precision, exceptional speed and gentle treatment approach,as demonstrated in multiple published studies it is the ideal platform for cut-ting-edge corneal surgery applications, including Flaps, Keratoplasty, Incisionsfor ICR and Lenticule Extraction with SMILE® from ZEISS.SMILE is redefining refractive surgery as we know it. ZEISS is at the forefrontof this minimally invasive Laser Vision Correction.The combination of the VisuMax and the MEL® 90* excimer laser from ZEISS addresses wide-ranging needs of the modern re f ractive surgical practice. In fact,it is the first refractive platform to perform all options of laser vision correction:PRK/LASEK (surface ablation surgery), Femto-LASIK/LASIK (flap surgery) as wellas Small Incision Lenticule Extraction (minimally invasive surgery).The result is a refractive platform that merges proven corneal surgicaltechniques with remarkable details as the basis for excellent, highlyindividualized treatment processes.3ZEISS VisuMaxPrecision in all its facetsThe VisuMax® is a truly innovative femtosecond laser system. With its perfectly coordinated components, it has precise cutting capabilities as well as proven efficacy, predictability and comfort.Lenticule ExtractionThe VisuMax is the first femtosecond laser system to perform the minimally invasive, Lenticule Extraction procedure. With SMILE® from ZEISS, a refractive lenticule as well as the incision through which it is extracted are created in a single step – without ablation or flap. Despite its proven predictability, a retreatment may be necessary in rare cases. If so, the initial incision created with SMILE can be extended into a flap with the option CIRCLE* from ZEISS.FlapThe VisuMax creates flaps of a highly predictablethick n ess and of adjustable geometries for Femto-LASIKand options based on it, such as PRESBYOND®, a binocular planning tool for patients with presbyopia.KeratoplastyWith the Keratoplasty option, the VisuMax covers several corneal transplant procedures, including lamellar and penetrating keratoplasty. High-precision cutting qualityand rapid incision speed enable the efficient preparationof precision corneal grafts and recipient corneas.Incision for ICRThe femtosecond laser technology of the VisuMax is also ideally suited for creating incisions in preparation of intracorneal ring (ICR) implantations. When defining tunnel parameters, it even performs inclined cutting geometries and ring tunnel seg-ments smaller than 360° with a high degree of flexibility.45ZEISS VisuMax highlightsThe building blocks of state-of-the-art femtosecond technologyA contact glass designed for the cornea Like the surface of the human cornea, VisuMax contact glasses are curved. Available in three dif-ferent sizes (S, M, L), they are optimally designed to fit the anatomy of the eye. As a result, the cor -nea largely retains its natural physiological shape. Artifacts are avoided in the cutting result, as isunnecessarily high IOP for the patient.Proven cutting precisionHigh-precision ZEISS optics provide an extremely focused laser beam. The result: the well aligned system of laser pulse energy and high pulse fre-quency leads to accurate incisions - at precisely the desired depth of the cornea, with three-di-mensional, curved incisions.Brilliant visual controlThe integrated high-quality ZEISS surgical micro-scope ensures precise and complete visual con-trol during every manual surgical manipulation. It includes a digital video camera for recordingsurgical procedures right on the spot.A smart unitThe sturdy, ergonomic pivoting patient supporting system is designed to provide maximum comfort during the treatment. It continuously monitors the patient’s position, automatically making needed adjustments. ZEISS VisuMax also incorporates an easy-to-use, interactive touchscreen and intui-tive software to assist the surgeon at every step throughout the procedure.Efficiency that pays offWith a pulse frequency of 500 kHz, the ZEISS VisuMax enables short treatment times, making procedures more comfortable for both physicians and patients. The result is an efficient workflow and a higher throughput of satisfied patients.Reassurance right on the spotAs a universal workstation for corneal surgery, the system features integrated slit illumination to monitor treatments and immediately control results – without the patient needing to be moved.ZEISS SMILEMinimally invasive surgerySMILE® from ZEISS is turning the world of refractive surgery on its head. The latest application is described as “LASIK without a flap andPRK without pain.”1 And ZEISS is leading the way – with SMILEfor Lenticule Extraction.FlaplessThe ZEISS VisuMax® is the first femtosecond laser system to support this unique minimally invasive laser vision correction procedure. Thereby, a highly precise, precalculated lenticule is created inside the intact cornea and removed via a small incision. Minimally invasiveRequiring no flap, SMILE offers the potential for fewer transected nerves, significantly reduced incidence of transient dry eye syndrome, and a lower risk of infection and epithelial ingrowth. Smaller incisions also improve epithelium healing.SeamlessThe lenticule creation and extraction areperformed without interruption. Also,the patient doesn’t need to be moved.That’s why SMILE offers a fast, seamlesstreatment.Excellent outcomesAdvanced laser vision correction withSMILE promotes more efficient work-flows, short treatment times and littlestress for patients – as well as excellentoutcomes with high predictability,including for higher refraction values.Highlights of SMILE and thecorresponding method• Small incision of 2-4 mm• Side-cut length up to 80 % shorterand cap incision area up to 30 %smaller than Femto-LASIK flap• Potentially lower incidence oftransient dry eye syndrome and lessnerve transection thanks to smallestincisions without flaps• Less risk of infections and epithelialingrowth• Good reproducibility of the lenticule,irrespective of individual cornealcharacteristics and ambient conditions• Excellent predictability, particularlyfor higher refraction values• Efficient treatment process withoutpatient having to switch places1 Rupal Shah, MD, Institute of Laser Medicine, Mumbai, India67Refractive correction with ZEISS SMILEThree treatment stepsLenticule creationA small piece of corneal tissue (lenticule) and a small incision are created inside the intact cornea.Lenticule removalThe lenticule is removed through the incision with minimal disruption to the corneal biomechanics.Impairment is correctedRemoving the lenticule changes the shape of the cornea, thereby achieving a vision correction.High-precision flaps, grafts and incisionsAnd a new level of Femto-LASIK workflow efficiency For treatments such as conventional Femto-LASIK including PRESBYOND® Laser Blended Vision, the VisuMax® delivers highly precise flaps. Together with the MEL® 90 excimer laser and the CRS-Master®* treatment planning station, ZEISS provides an optimal combination forefficient workflows and excellent results.MEL90 excimer excellence Precise, efficient, safe and fast – the ZEISS MEL 90 excimer laser is a true workhorse for performing a broad range of corneal surgical procedures. The MEL 90 is combining your experience with modern advancements like the FLEXIQUENCE® switch function and outstanding intraoperative ablation speed of up to 1.3 seconds per diopter**. CRS-Master for individual treatmentsThe ZEISS CRS-Master is an advanced treatment planning tool for the remote planning of regular and customized topo g raphy-guided treatments. PRESBYOND Laser Blended Vision,a treatment option for presbyopic patients, is another key application of the CRS-Master.Cut right with ZEISS VisuMax• High-precision flaps• High reproducibility and flap thicknessconsistency• Easy flap repositioning• Smooth stromal bed surfaces• Proven workflow• Prevents unnecessarily raised IOPPivoting patient supporting systemMove patients comfortably and quicklyfrom the femtosecond to the excimerlaser with the pivoting patient sup-porting system.** LASIK, myopia, 500 Hz, OZ: 6 mm8Customized corneal grafts for keratoplasty With the Keratoplasty option, the ZEISS VisuMax becomes a state-of-the-art workstation for customized corneal grafts, enabling smooth lamellar and circular incisions for Penetrating Keratoplasty (PKP), Deep Anterior LamellarKeratoplasty (DALK) and Descemet’s Stripping Endothelial Keratoplasty (DSEK).The practical Keratoplasty adapter provides a robustand sterile work surface for preparing corneal graftsSpecially designed curved contact glass (type KP) pre-vents unnecessary compression of the corneal tissueSeparation of the cut lamellae from the recipient cor n eaas viewed through the VisuMax surgical microscope*MEL 90, CRS-Master, PRESBYOND and CIRCLE are not approved for sale in the United States.• Easy-to-understand ICR user interface• Rapid, intuitive entry of treatmentparameters• Stored user-defined cutting geome-tries for improved workflowFreely variable cuttingparameters, even forincisions parallel tothe posterior cornealsurfaceFlexible access for ICR incisionsEquipped with the Incision for ICR option, the ZEISS VisuMax offers uniqueadvantages for intracorneal ring (ICR) implantations. Even inclined cuttinggeometries and partial segments from 90° to 270° are possible. Cornealtunnels are prepared quickly, precisely and with a high degree of flexibility.910Technical dataVisuMax from ZEISSSystem components Patient supporting system, including platformIntegrated uninterruptible power supply (UPS)Surgical microscope with additional slit illuminationVideo camera with integrated digital recordingLaser parameters Wavelength1043 nmPulse duration220-580 fsLaser pulse rate500 kHzInstallation and set-up conditionsWeight870 kg (including patient supporting system, platform, UPS)Footprint standalone L x W: 3.80 m x 4.40 mFootprint MEL® 90 with VisuMax® 90°L x W: 3.92 m x 3.94 mFootprint MEL 90 with VisuMax 180°L x W: 4.50 m x 3.79 mElectrical connection 100-240 V, 50/60 Hz, max. 16 ASeparately fused circuitOperating conditionsRoom temperature 18 to 25 °CAtmospheric humidity 30 to 70 %Accessories Single-use contact glasses Treatment Pack (sizes S/M/L and type KP)Keratoplasty adapter for patient supporting system11Carl Zeiss Meditec AG Goeschwitzer Strasse 51–5207745 Jena Germany/med/contacts /visuma0297VisuMax SMILE MEL 90PRESBYONDCRS-MasterE N _34_010_0007V P r i n t e d i n G e r m a n y C Z -X /2020 I n t e r n a t i o n a l e d i t i o n : N o t f o r s a l e i n t h e U S .T h e c o n t e n t s o f t h e b r o c h u r e m a y d i f f e r f r o m t h e c u r r e n t s t a t u s o f a p p r o v a l o f t h e p r o d u c t o r s e r v i c e o f f e r i n g i n y o u r c o u n t r y . P l e a s e c o n t a c t o u r r e g i o n a l r e p r e s e n t a t i v e s f o r m o r e i n f o r m a t i o n . S u b j e c t t o c h a n g e s i n d e s i g n a n d s c o p e o f d e l i v e r y a n d d u e t o o n g o i n g t e c h n i c a l d e v e l o p m e n t . V i s u M a x , S M I L E , R e L E x , M E L ,F L E X I Q U E N C E ,P R E S B Y O N D a n d C R S -M a s t e r a r e e i t h e r t r a d e m a r k s o r r e g i s t e r e d t r a d e m a r k s o f C a r l Z e i s s M e d i t e c AG o r o t h e r c o m p a n i e s o f t h e Z E I S S G r o u p i n G e r m a n y a n d /o r o t h e r c o u n t r i e s .© C a r l Z e i s s M e d i t e c A G , 2020. A l l r i g h t s r e s e r v e d .。

B l u e S c o p e B L6800BHandheld multi‐functional, multi‐technology test platform forEthernet, IP, SONET/SDH/PDH, OTN & Fibre ChannelKey BlueScope Benefits:∙Unmatchable market performance▪Test up to 32‐Mulistreams each with customizable traffic profiles.▪Powerful Packet Flooding. Flood nearly any field of a packet including MAC, VLAN, MPLS with Layer 3 & 4 payload options.▪Dual port Packet Capture and Analysis utilizing WireShark engine▪The most compact OTN tester on the market. Supports OTU‐1/2/1E/2E/1F/2F▪Unparalleled physical layer testing on all optical transport methods and line rates.∙Software license controlled features for upgrades or maintaining test standards as they are defined, then certified.▪Instant (DIY) remote/field upgradable; via a software only license key.▪Never lose a test capability/feature due to lost, forgotten, or damaged hardware modules.∙Linux Operating System▪Less susceptibility to viruses and malware. Known in the IT industry for being more stable than alternatives.Linux the OS choice for hand held testers and utilized in the Bluescope!BlueScope Highlights:∙Handheld test set hardware platform that supports both 1/10 GbE Ethernet, SONET/SDH/PDH, Fiber Channel, OTN, VOIP, IPTV, WLAN.∙Rapid Boot‐up∙Eight Hours battery stand time and approximate four hours of battery test time.∙Remote control through VNC and a CLI.∙Dual port operation enables performing two tests simultaneously∙Bluetooth support to easily offload test results or transfer test configurations.∙Customizable platform. Avoids technology obsolescence. Choose your ports, line rates and testing options you require now. Then invest in what you require. Bluescope is upgradeable for your future testing by you and can be fullyconfigured by you, whenever your test requirements, testing demands, financial position changes. Just add ports,features, and software options etc. in the future. Truly “pay as you grow” handheld test platform.Ethernet & IPBlueScope Ethernet Standard Features: ∙ Throughput Test (Single Stream)∙ Packet Filtering∙ IP Tools (Ping, DHCP, Trace Route)∙ In ‐Service Traffic Monitoring (Non ‐Intrusive Mode) ∙ MPLS (stacking up to 3 MPLSs) ∙ VLAN, Q ‐in ‐Q (up to 3 VLANs) ∙ Cable Diagnostics ∙ Remote Control via VNC ∙ Report Generation (PDF, CSV and TXT)BlueScope Ethernet SW Options:∙ (ET ‐1) Single 1GB port (ET ‐2) Dual 1GB port (ET ‐3) Single 10GB port(ET ‐4) Dual 1GB & Single 10GB port∙ (ET ‐5) Loopback Mode (L1‐L4, auto, filtered) ∙ (ET ‐6) Throughput multi ‐streams (4 streams)∙ (ET ‐7) RFC2544 (Network Equipment Benchmarking Test) ∙ (ET ‐8) Packet Capture and Decode via WireShark ∙ (ET ‐9) Throughput 32 multi ‐streams∙ (ET ‐10) Packet Flooding – Mac/VLAN/IP/User Defined Field ∙ (ET ‐11) L1/Unframed BERT (Cable BERT ‐RJ45, Unframed BERT ‐SFP Optic)∙ (ET ‐12) Network Discovery ∙ (ET ‐13) 100 FX/LX (Optic)BlueScope Ethernet SW Options:∙ (ET ‐14) Y.1564(EtherSAM)∙ (ET ‐15) PBB/PBB ‐TE(MAC ‐in ‐MAC) ∙ (ET ‐16) SyncE/1588 ∙ (ET ‐17) IPV6∙ (ET ‐18) EtherOAM Y.1731 (available early 2013) ∙ (ET ‐19) Asymmetric Testing (available early 2013)∙ (ET ‐20) One ‐Way Delay Measurement using 1588 or GPS (available early 2013)∙ (ET ‐21) Web Browser and HTTP Testing ∙ (ET ‐22) CLI Interface ∙ (WA ‐1) 10GbE WAN PHY∙ (WA ‐2) WLAN 802.11 a/b/g testing ∙ (PT ‐1) IPTV Quality Metrics∙ (PT ‐2) IPTV Decode (available early 2013) ∙ (VO ‐1) VoIP Quality Metrics∙ (VO ‐2) VoIP Signaling and Vocoding (available early 2013)Ethernet IP Applications∙Troubleshoots Ethernet/IP networks, captures and analyzes packets, and identifies network problems.∙Tests Carrier Ethernet transport to verify class of service (CoS), Triple‐Play Service, and Ethernet circuit transparency.∙Supports Packet Transport Network (PTN) testing with MPLS‐TP traffic generation and QoS analysis, along with simultaneous verification of OAM Label 13 or 14 operation.∙Confirms higher‐layer Ethernet data applications and services at 10Mbps to 1Gbps rates with Ipv4 and IPv6∙Tests Layer 1‐4 Ethernet/IP SLAs with RFC 2544 for up to 3 VLAN tags, Q‐in‐Q, and MPLS encapsulation.∙Verifies automatically SLA compliance according to Y.1564, including different traffic profiles per service, and KPI compliance for all committed services concurrently.Ethernet IP Testing LifecycleInstallation∙RFC2544, including frame delay variation, asymmetric rates, and concurrent results to reduce overall test time.∙Y.1564 EtherSAM automated SLA validation including bandwidth profiles and KPI compliance for quickly verifying multiple services.∙Carrier Ethernet testing with PBB, MPLS, MPLS‐TP, VLAN and Q‐in‐Q.Troubleshooting∙Line rate packet capture up to 10Gbps.∙Packet decodes with integrated WireSharkCarrier Ethernet Installation TestingFor years Ethernet/IP has been transported throughout carrier networks encapsulated in other data‐link layer technologies thatevolved into a carrier‐grade technology because of operations, administration, and maintenance (OAM) standards such as ITU‐Ty.1731, IEEE 802.1ag, and 802.3ah. Ethernet now possesses many of the characteristics that made SONET/SDH the transporttechnology of choice; end‐to‐end circuit transparency, redundancy, and full‐featured OAM for circuit‐based performancemanagement and alarming. The BlueScope delivers a much‐needed tool set for provisioning and troubleshooting Ethernet networksthat substantially improves installation and troubleshooting times, thereby granting error‐free operation and a significant reductionin operating expense.RFC2544 TestingThe BlueScope delivers all the Carrier Ethernet testing needed to qualify Ethernet‐based transport networks. RFC2544 is the defacto industry standard for Ethernet circuit installation. In addition to supporting Ethernet throughput or committed information rate (CIR), frame delay (FD) or latency, frame loss (FLR), and back‐to‐back burst testing as called out in the RFC, the BlueScope also tests forpacket jitter or frame delay variation (FDV) to ensure the circuit is ready to transport time‐sensitive services such as IPTV and VoIP.Using a pair of test sets and Asymmetric RFC testing, users can validate Ethernet Virtual Circuits (EVCs) with different upstream and downstream CIRs, or they can test sequentially in both directions to ensure that key performance indicators (KPIs) are met acrossany connection type.ITU‐T Y.1564 EtherSAM Service Activation TestingY.1564 EtherSAM allows for fast and easy verification of SLAs for differentiated services including validation of different bandwidthprofiles like committed information rate (CIR), extended information rate (EIR) and maximum bandwidth. Pass / Fail results for KPIs including CIR, frame delay (FD), frame delay variation (FDV or packet jitter) and frame loss rate (FLR) are provided independently forup to 16 services. Out of sequence frames and available seconds are reported per Y.1564.Verifying CoS with Multiple StreamsMulti‐stream testing generates several streams of traffic at the Ethernet, IP, and TCP/UDP layers (Layers 2‐4) to emulate various types of traffic with the appropriate CoS mappings so that users can assess the impact of traffic prioritization on the overall network architecture while confirming proper network element queuing, policing, and shaping. Up to 32 individually configured streams enable generation and analysis of per stream key parameters such as VLAN ID and priority, TOS/DSCP marking, packet size,source/destination IP and MAC address, and source/destination TCP/UDP ports. Users can configure constant or ramp traffic to simulate near real‐world traffic before actually delivering a service. This level of testing confirms the network design as well as drastically reduces post‐installation troubleshooting.BER and Latency TestingThe BlueScope supports optical Layer 1 (L1) BER testing for stress testing the underlying physical transport link. A standard 2^23 pattern is used to obtain key QoS measurements including bit error rates, pattern sync, latency, line coding, and signal/power levels.Ethernet OAM, VLAN, Q‐inQ, MPLS and PBB Tunneling TechnologiesEthernet tagging and encapsulation is commonly used to improve the scalability of Ethernet networks by isolating customer traffic and, in the case of provider backbone bridging (PBB), minimizing the number of MAC addresses that equipment must learn. Regardless of the encapsulation and tagging used, the BlueScope tests CoS to confirm KPIs such as CIR, FD, FDV, and FLR. Support for virtual local area network (VLAN) tags, Q‐in‐Q VLAN tags, PBB (also known as MAC‐in‐MAC) and multi‐protocol label switching (MPLS), the BlueScope allows testing at any part of the Metro network.Ethernet Timing Synchronization Verification using 1588v2 PTP and G.826x SyncECritical network timing and frequency synchronization testing enables service providers to analyze emerging 1588v2 PTP and Synchronous Ethernet (SyncE) protocols greatly reducing expenses for mobile backhaul and LTE by eliminating the need forTDM/GPS. Wireless backhaul providers can now verify whether Ethernet links can transfer PTP protocols by connecting to a PTP master and measuring critical packet parameters such as PDV with simultaneous network traffic loading. SyncE testing recovers the timing of an incoming Ethernet interface for the tester’s transmitter. Capturing and decoding the 1588v2 PTP and Ethernet Synchronization Messaging Channel (ESMC) messages allows operators to verify and troubleshoot proper configuration and operation of synchronization networks.Carrier Ethernet Fault IsolationIn the ever‐changing Ethernet and IP world providers must quickly, cost‐efficiently, and reliably troubleshoot problems at all layers of the stack. The BlueScope provides powerful line‐rate packet capture at Ethernet speeds up to 1GigE without dropping a single packet. When troubleshooting problems occur intermittently or inconsistently, it supports multiple traffic filters and triggers, including 16‐byte pattern identification, to isolate the exact problem and minimize the amount of information gathered.The BlueScope natively supports WireShark for on‐instrument packet decode. Additionally, users can save the captured traffic in a standard pcap file format and export it via USB or FTP through the management port for further analysis.SONET/SDH/PDHThe BlueScope 6800B performs BER testing on all line interfaces in end‐to‐end or loopback applications, inserts errors and alarms to verify NE conformance and connectivity, and measures BERs from DS1 (1.5M)/E1 (2.048M) rates to OC‐192/STM‐64.MappingsSONET/SDH mappings include all intermediate mappings down to VC‐4/VC‐3 in addition to BERT payload with multiple PRBS choices.SONET/SDH/PDH Overhead Byte Manipulation and AnalysisUsing the overhead byte manipulation and analysis capability, users can modify K1 and K2 bytes to test automatic protection switching (APS) to specify and identify user‐configurable path trace messages and payloads. The path overhead (POH) capture feature facilitates troubleshooting end‐to‐end problems. The Bluescope 6800B supports manual capture, capture on alarm, and capture based on user‐defined triggersPhysical Layer TestingPerform physical layer testing to verify dark fiber and line continuity across all optical transport methods and line rates. Support for unframed STM‐1/4/16/64, Fiber Channel 1x/2x/4x/10x, OTN OTU‐1/2/1E/2E/1F/2F, 1.250G(1GE), 10.313(10GE) and 3.1G (CPRI).Service Disruption measurementsThe Bluescope 6800B measures the protection switch times of SONET/SDH rings and their effects on tributaries. By measuring various error and alarm conditions on the tributaries, providers can verify that their transport network is providing adequate redundancy to guarantee SLAs.Multi‐Channel ViewDrill down to view the path hierarchy in its entirety on one screen with automatic detection of payload type (concatenated or non‐concatenated) for SONET ( 48x STS‐1 and 28x VT 2/1.5) and SDH (48x AU‐3 and 28x TU12/TU11).Line Through ModeConnecting the test unit in‐line provides not only monitoring capabilities but also the possibility of injecting errors. This provides for an effective tool in serice‐disruption testing.SDH/PDH Alarm/Error GenerationGenerate Alarms for:LOS, LOF, OOF,RS‐TIM, MS‐AIS, MS‐RDI, AU‐LOP, AU‐AIS, TU‐LOP, TU‐AIS, HP‐UNEQ, HP‐PLM, HP‐TIM, HP‐RDI,HP‐SRDI, HP‐CRDI, HP‐PRDI, HP‐TC‐UNEQ, HP‐TC‐LOMF, HP‐TC‐AIS, HP‐TC‐RDI, HP‐TC‐ODI, LP‐UNEQ, LP‐PLM, LP‐TIM, LP‐RFI, LP‐RDI, LP‐SRDI, LP‐CRDI, LP‐PRDI, LP‐TC‐UNEQ, LP‐TC‐LOMF, LP‐TC‐AIS, LP‐TC‐RDI, LP‐TC‐ODIGenerate Errors for:FAS, B1, B2,B3, MS‐REI, BIT,HP‐REI, HP‐TC‐IEC, HP‐TC‐REI, HP‐TC‐OEI, LP‐BIP, LP‐REI, LP‐TC‐IEC, LP‐TC‐REI, LP‐TC‐OEIBlueScope SONET/SDH Options:∙(SO‐1) OC‐3/12/48 (STM 1/4/16)(SO‐2) OC‐192 (STM‐64)(SO‐3) OC‐3/12/48/192 (STM 1/4/16/64)∙(SO‐4) Unframed Line Rate (Requires SO‐1,2 or 3)∙(SO‐5) Multi‐Channel View (Requires SO‐1, 2 or 3)∙(SO‐6) Signal Delay emulator (injection of signal delay in unframed line rates; Requires SO‐4)BlueScope PDH Options: ∙(PD‐1)E1/T1 (DS1)(PD‐2)E3/T3 (DS3)(PD‐3)E1/T1, E3/T3OTNOTN is the next generation network designed to combine and accelerate the benefits of SDH/SONET with the bandwidth expandability of DWDM (Dense wavelength division multiplexing).Test end‐to‐end connectivity by transmitting and receiving OTN signals with the ability to insert and analyze errors and alarms in network troubleshooting and equipment verification applications.TCM with Error/Alarm detectionVerify network element interoperability with the TCM bytes; Count, current rate and average rate for each error, SDT (Service disruption Time) measurements and RTD (Round Trip Delay) measurements. Verify OTN alarms and errors with injection capabilities such as loss of frame (LOF), alarm indication signal (AIS), and backward defect indication (BDI).FEC TestingTransmit and analyze correctable and uncorrectable FEC errors to verify a network element’s ability to correct conditions through the use of FEC enabled signals. Correctable and uncorrectable FEC error positions are accumulated and monitored through a graphical hierarchy window which allows users to easily recognize the position of the FEC error.Features programmable FEC error generation functions that allows the user to define a detailed position for correctable FEC errors and un‐correctable FEC errors.Line Through ModeConnecting the test unit in‐line provides not only monitoring capabilities but also the possibility of injecting errors. This provides for an effective tool in service‐disruption testing.BlueScope OTN Options:∙(OT‐1)OTU‐1 (2.66G/STM‐16)Requires SO‐1(OT‐2)OTU‐2 (10.7G/STM‐64)Requires SO‐2(OT‐3)OTU‐3 (2.66G & 10.7G / STM‐16 & STM‐64) Requires SO‐3(OT‐4)OTU‐4 (10G Ethernet over OTU‐2 [OUT‐1e/2e] available early 2013)Fibre ChannelThe BlueScope B6800B tests 1x, 2x, 4x and 10x Gbps Fibre Channel (FC). Users can manipulate various fields of the FC frames to emulate end customer traffic and perform BER measurements on L1 and L2 circuits. The BlueScope supports buffer crediting capability, which lets providers verify the effect of delay on the link throughput and test the ability of the link to obtain the optimum buffer credit values. The BlueScope also allows users to turn up storage area networks (SANs), producing reliable throughput, packet loss, RTD, and burstability results with consistent test methodology.BlueScope Fiber Channel Options:∙(FC‐1) Fiber Channel 1x/2x(FC‐2) Fiber Channel 4x(FC‐3)Fiber Channel 1x/2x/4x(FC‐4)Fiber Channel 10x (Available 2013)(FC‐5)Fiber Channel 1x/2x/4x/10x (10x Available 2013)Hardware Specifications:∙Ports:▪(2) SFPs (1000BASE‐SX/LX/ZX, 100‐FX/LX/SX)▪(2) 10/100/1000Base‐T (RJ45)▪(1) XFP▪(1) BNC connectors (Tx/Rx) 34‐45M▪(1) Bantam(Tx/Rx) : 1.5M ‐ 2M▪(1) SMA(Tx) : Tx Reference Clock Out▪(1) SMA: External clock input 1.544 ‐2.048 Mbps / 1.544m, 2.048 m, 10M / Any clock speed▪(1) GPS Signal input▪(1) HDMI output▪(1) 3.5mm headset audio jack and mic support.∙Port Configuration:▪BL6800‐01 (1Gb‐Single Port), BL6800‐02 (1Gb‐Dual Port), BL6800‐12 (10Gb‐Single Port, 1Gb‐Dual Port)▪BL6800‐01P (including PDH), BL6800‐02P (including PDH), BL6800‐12P (including PDH) ∙Dimensions:▪Size: 172.5 (W) x 227 (H) x 58.5 (D) mm▪Weight: 1.3 kg with Battery, Battery (0.3 kg)∙Operating Temp: 0Ԩ~40Ԩ∙Storage Temp: ‐20Ԩ~ +70Ԩ∙Display: 5.7 Color TFT‐LCD Touch Screen∙User Interface: Touch Screen & Keypad∙Humidity: 10% ~ 90%∙Power:▪AC adaptor: 100V~240 V(50Hz/60Hz)▪Removable/Rechargeable lithium ‐Ion Battery▪Battery life: 3 hours typical, 8 hour in standby mode▪Charging time: 1 ~ 2 hours∙Memory:▪16GByte internal Flash memory includedContact Information:Web: US & Canada:Support: ************************Tel: +1 408 841 9689Sales: **********************Fax: +1 408 841 9607。

数字化试验平台TDM3000作者：来源：《中国计算机报》2009年第02期北京锐峰协同科技股份有限公司是业界领先的企业级数字化试验解决方案专业供应商,在2003年率先提出数字化试验平台(Testing Data Management,TDM)的概念,并组建专业开发团队进行研发,凭借丰富的工程经验和雄厚的技术实力,创造了多项核心技术和系列产品,并研发出适用于制造业的数字化试验平台TDM3000。

该平台可以帮助用户在新产品设计和试验过程中大幅提高试验效率,节约时间,降低产品成本并提高产品质量。

TDM3000作为锐锋公司的旗舰产品,经过5年发展历程,用户群从最初的航空领域,逐步发展到航天、船舶、兵器、电子、汽车、能源、科研等多个领域,成为用户群多,易用性好的数字化试验产品。

TDM3000是功能较强、应用广泛的数字化试验平台,包含试验规划设计、试验设备配置、试验综合测控、试验监控发布、数据分析处理、试验结果评估等全部应用功能,并且结合了试验资源管理和数据管理功能,全面提高了各阶段试验的数字化水平。

案例:2007年,中国运载火箭研究院在对多家厂商和产品进行充分调研比较之后,最终选择了锐峰公司提供的TDM3000产品,并首次在运载火箭的控制系统试验中实现了综合测试数据的智能解析、快速诊断和自动判读,自动生成判读表和判读结果,为系统可靠性增长研究奠定坚实基础。

中国运载火箭研究院看重的是锐锋的品牌优势和技术优势,锐锋公司是业界领先的数字化试验解决方案专业供应商,始终坚持发展自有核心技术,并不断将新技术应用到产品中,其所拥有的海量试验数据优化技术、多设备集成测控技术、开放式分析处理技术、动态试验业务建模技术,填补了业界空白。

中国运载火箭研究院的该项目负责人表示:“是优秀的品牌、先进的技术和可靠的技术服务支持,让我们最后选择了TDM3000产品。

该产品得到广泛应用的多个型号产品已经稳定运行近两年,在保障我国神舟七号载人航天飞船的顺利发射中表现卓越。

实验名称：多模式智能响应性光学平台实验实验目的：1. 了解多模式智能响应性光学平台的原理和组成。

2. 掌握实验操作步骤，包括样品制备、激发光源选择、光学性能测试等。

3. 分析不同刺激条件下光学材料的响应特性，探讨其在信息安全应用中的潜在价值。

实验时间：2023年X月X日实验地点：XX大学光学实验室实验人员：XXX、XXX、XXX实验仪器：1. 光谱仪2. 紫外-可见分光光度计3. 高能X射线源4. 热场刺激装置5. 实验样品制备设备实验原理：多模式智能响应性光学平台是一种能够在外界刺激下产生多种响应特性的光学材料。

本实验采用单一稀土发光离子Sm3辅助基质发光的方法，制备了具有多模式响应性的光学材料。

在外界刺激条件下，该材料能够实现发光颜色由蓝紫色到玫瑰粉色的动态变化，从而实现信息的安全传输和识别。

实验步骤：1. 样品制备：- 将Sr2YGaO5材料作为基质，掺杂单一稀土发光离子Sm3，制备成所需的光学材料样品。

- 将制备好的样品进行研磨、过筛等处理，以确保样品均匀性。

2. 激发光源选择：- 选择紫外-可见光作为激发光源，以激发Sm3离子的发光。

- 选择高能X射线源作为激发光源，以测试材料在高能射线激发下的响应特性。

3. 光学性能测试：- 使用光谱仪测试样品在不同激发光源下的发射光谱，分析发光颜色变化。

- 使用紫外-可见分光光度计测试样品在不同激发光源下的吸收光谱，研究材料的光吸收特性。

- 使用热场刺激装置测试样品在不同温度下的发光颜色变化，分析材料的热响应特性。

4. 数据分析：- 对实验数据进行整理和分析，绘制发光光谱、吸收光谱等图表。

- 讨论不同刺激条件下光学材料的响应特性，分析其在信息安全应用中的潜在价值。

实验结果与分析：1. 在紫外-可见光激发下，样品发射光谱呈现蓝紫色，随着激发光强度的增加，发光颜色逐渐变为玫瑰粉色。

2. 在高能X射线激发下，样品发射光谱呈现蓝紫色，与紫外-可见光激发下的结果一致。

光纤通信Zemax、optisystem实验程佑梁实验一Zemax仿真设计实验目的1．熟悉Zemax实验环境，练习使用元件库中的常用元件组建光学系统。

2．利用Zeamx的优化功能设计光学系统并使其系统的各项性能参数达到最优。

实验原理启用Zemax，如何键入wavelength，lens data，产生ray fan，OPD，spot diagrams，定义thickness solve以及variables，执行简单光学设计最佳化，即分为以下两个部分。

1、lens data editor首先叫出ZEMAX的lens data editor(LDE)，什么是LDE呢？它是你要的工作场所，譬如你决定要用何种镜片，几个镜片，镜片的radius，thickness，大小，位置……等。

然后选取你要的光，在主选单system下，圈出wavelengths，依喜好键入你要的波长，同时可选用不同的波长等。

现在在第一列键入0.486，以microns为单位，此为氢原子的F-line 光谱。

在第二、三列键入0.587及0.656，然后在primary wavelength上点在0.486的位置，primary wavelength主要是用来计算光学系统在近轴光学近似(paraxial optics，即first-order optics)下的几个主要参数，如focal length，magnification，pupil sizes等。

再来我们要决定透镜的孔径有多大。

既然指定要F/4的透镜，所谓的F/#是什么呢？F/#就是光由无限远入射所形成的effective focal length F跟paraxial entrance pupil的直径的比值。

所以现在我们需要的aperture就是100/4=25(mm)。

于是从system menu上选general data，在aper value上键入25，而aperture type被default为Entrance Pupil diameter。

临床实验平台设计在临床实验中，一个有效的实验平台设计是非常关键的。

一个好的实验平台不仅可以提供一个安全的环境，还可以提供准确可靠的数据和结果。

为了满足这些需求，临床实验平台的设计必须经过深思熟虑和精心计划。

本文将讨论临床实验平台设计的关键因素和步骤。

一、需求分析在设计一个临床实验平台之前，首先需要进行需求分析。

这包括确定实验的目的、目标人群、实验流程以及需要收集的数据等。

通过充分了解这些需求，设计人员可以更好地规划实验平台的功能和结构。

二、硬件设施临床实验平台的硬件设施是关键的一部分。

这包括实验室的布局、实验设备和仪器等。

实验室的布局需要充分考虑人员流动和任务分配的便利性。

实验设备和仪器的选择应根据实验需求和质量要求进行，同时要确保其可靠性和安全性。

三、数据采集与处理在临床实验中，数据的采集和处理非常重要。

为了准确地记录实验结果，需要选择适当的数据采集工具和技术。

此外，数据的处理和分析也是不可忽视的部分。

选择适当的数据处理软件和算法可以帮助研究人员更好地理解实验数据。

四、安全措施在临床实验中，安全始终是最重要的考虑因素之一。

为了保障实验人员和患者的安全，实验平台设计必须符合相关的安全标准和规范。

这包括实验环境的卫生和消毒，实验设备的维护和保养，以及实验人员的培训和安全指导等。

五、质量控制质量控制是临床实验平台设计中不可或缺的一部分。

为了保证实验结果的准确性和可靠性，需要建立一套完善的质量控制体系。

这可以包括标准操作程序的制定、标准质控样品的使用以及严格的质量评估等。

六、文件管理在临床实验中，文件管理是非常重要的一项工作。

为了确保实验数据和结果的保存和查阅，需要建立一个有效的文件管理系统。

这包括文件的分类和编号、文件的保存和备份以及文件的检索和归档等。

七、人员培训最后，人员培训是实验平台设计中不可或缺的一环。

为了确保实验的顺利进行，所有相关人员需要接受专业的培训和指导。

这包括实验操作技术的培训、实验流程的掌握以及安全操作的培训等。