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`English Final Exam for 2018 Doctoral Students(Dec. 27, 2018)Student NO.___________________ Name____________________Paper OneEnglish Writing for Biomedical PurposesPart IDirections: Choose the right one from the four choices marked A, B, C or D.1.Inconsistent with previous studies, our results from a large cohort of patients_____ this long-standing assumption.A. contrastB. compareC. reinforceD. challenge2.Patients who were receiving mechanical ventilation were considered _____ ifthey met the following modified criteria for acute lung injury or the acute respiratory distress syndrome.A. acceptableB. eligibleC. considerableD. credible3.However, results from several small studies in humans have yielded inconclusiveevidence of a beneficial _____ of ascorbic acid on lead toxicity.A. effectB. effectivenessC. affectionD. efficacy4. A _____ disease such as diabetes can affect the whole body.A. systematicB. systemicC. generalD. whole5.All tumours from AOM treated mice were _____ to histological examinationafter routine processing and haematoxylin and eosin staining.A. subjectB. subjectedC. injectedD. directed6.Serious arrhythmias are prevented whenever possible by _____ treatment ofpremonitory signs or otherwise controlled immediately after recognition byappropriate therapy.A. aggressiveB. recessiveC. abusiveD. successive7.CT scans and digital subtraction angiograms of these patients wereretrospectively reviewed by two investigators in _____ to evaluate tumor feeding vessels.A. agreementB. consentC. approvalD. consensus8.The beneficial effects of pharmacotherapy for chronic obstructive pulmonarydisease (COPD) are well _____.A. elusiveB. confirmedC. establishedD. achieved9.Chemically induced colon carcinogenesis in rodents is also suppressed by _____of NSAIDs.A. treatmentB. administrationC. managementD. registration10.Thus, it _____ further investigation of whether mfat-1 expression in diseasemodels such as non-obese mice can mitigate the development of type 1 diabetes.A. elucidatesB. interpretsC. warrantsD. guarantees11.We used a _____ questionnaire to determine whether participants met theAmerican College of Rheumatology survey criteria for gout.A. supplementaryB. complimentaryC. complementaryD. sentimental12.Ubiquitinated p53 was detected _____ immunoblotting _____ the DO-1 p53antibody.A.by...withB.for...inC.with...forD.via...on13.Cells were placed _____ a 60Co Picker unit irradiator (1.56 Gy/min) andexposed _____ 8 Gy -irradiation.B.in...withC.in...toD.on...to14.Our aim was to _____ whether or not vitamin D supplementation or deficiencyin infancy could affect occurrence of type 1 diabetes.A. studyB. ascertainC. clarifyD. research15._____ intake of purine-rich vegetables or protein is not associated with anincreased risk of gout.A. IntermediateB. ModerateC. MediumD. Immediate16.We would like to express our _____ to all the interview partners at the WorldHealth Organization for their time, expertise, and confidence.A. magnitudeB. altitudeC. aptitudeD. gratitude17.Apoptosis was analyzed _____ a FACScan(Becton Dickinson) and quantified_____ percentage of annexin-V and PI-positive.A. in...asB. on...forC. on...asD. by...for18._____ primary culture, the cells were resuspended _____ Dulbecco’s modifiedEagle’s medium containing 10% (vol/vol) fetal bovine serum and gentamicin.A.By...withB.For...inC.To...byD.At...over19.Ebola virus can spread among humans primarily through unprotected directcontact of skin or mucous membranes with blood or body fluids of a person who is ill with EVD, or the _____ of a deceased patient who had EVD.A. corpusB. corpseC. corpsD. lupus20.Treatment _____ a low dose of cadmium chloride (1 mg/kg) showed no effect onthe testis, and DAZL staining was comparable _____ control (Fig.1B).A.of...toC.at...asD.at...with21.P-gp expression was strongly induced by SJW (400% increase at 300 µg ml-1)and by HYP (700% at 3 µM) _____ a dose-dependent manner.A.onB.inC.withD.by22.Baseline ADMA levels were higher in patients who had died than in patientswho were alive at 1 year follow-up (1.23［0.98 to 1.56］_____ 0.95［0.77 to 1.20］mmol/L, p＜0.001).A.fromB. B. versusC. C. toD.D. with23.The _____ for taking this approach is clear enough.A. rationaleB. notionC. hypothesisD. explanation24.This drug contains no _____ substances and has no side effects.A. toxinB. tonicC. toxicD. poisonous25.The risk of DVT and PE were significantly _____, and were highest in the firsttwo weeks, after urinary tract infection.A. roseB. raisedC. arousedD. arose26.Data was collected in the first year of life about frequency and dose of vitamin Dsupplementation and _____ of rickets.A. prescriptionB. absenceC. presentationD. presence27.Prostacyclin (PGI2) is produced from the endothelium throughcyclooxygenase-1, and binds to specific _____ in SMCs and activates adenylate cyclase.A. receiversB. receptorsC. receiptsD. recipient28.To _____ the hypothesis, experiments involving Western blots and RNAinterference were performed.A. testifyB. verifyC. justifyD. certify29.Over the past 5 decades, the proportion of DM-associated cardiovasculardiseases has been on the rise, thus _____ the need for more efforts to aggressively control the risk factors of CVDs.urgingA. urgingB. highlightingC. pressingD. enlightening30.Children _____ of having rickets during the first year of life had a RR of3.0(1.0-9.0) compared with those without the disease.A. doubtedB. suspectedC. diagnosedD. suspended31.Curcumin, a traditional medicine, exhibits anticarcinogenic andanti-inflammatory _____.A. asperityB. propertiesC. perspectivesD. prosperity32.In this study, we aimed to examine the rate of thrombolytic therapy in youngstroke patients with and without a history of migraine. We _____ that migraine would be associated with a lower rate of thrombolytic therapy.A. hypothesizesB. speculatedC. postulatedD. stipulated33.The mechanism by which PA28 exerts these effects has not been _____.A. anticipatedB. elucidatedC. remuneratedD. eliminated34.We utilized a previously described _____ to evaluate ubiquitination (Li et al,2013).A. agendaB. programC. portfolioD. protocol35.Surgical specimens of human colon cancer and adjacent normal colon mucosatissues were taken from eight Japanese patients who had _____ surgical operations for colorectal cancers at the National Cancer Center Hospital, Tokyo, and samples were immediately frozen in liquid nitrogen.A. undertakenB. undergoneC. conductedD. performed36.It consists of 10 pages of text, 2 tables, 2 pages of ____ to figures, and 6photocopies of figures.A. legendsB. accountsC. descriptionsD. introductions37.There have been no reports ____ of rosiglitazone–associated elevations in theaminotransferase level or hepatotoxicity.A. to dateB. right nowC. for nowD. to go38.As shown in Table 1, p8 was overexpressed in 71.1% of PC and in 100% of PCcell lines, ____ it was not overexpressed in MC.A. howeverB. althoughC. whereasD. albeit39.The RT-PCR assay was repeated at least three times per each sample to confirmthe ____of the results.A. reproducibilityB. availabilityC. probabilityD. likelihood40.____ asthma, Th2 cytokines are a crucial contributing factor of allergic airwayinflammation and AHR.A. In the case ofB. In case ofC. Regardless ofD. Irrespective ofPart IIDirections: Choose the right one from the given four tenses marked A, B, C or D.ResultsZebrafish nkx2.5 Can Activate myo-2 Expression When Expressed in C. elegans Body Wall Muscle.To determine whether zebrafish nkx2.5 __46__ similarly to che-22, we __47__ nkx2.5 in C. elegans Body Wall Muscle and examined expressionof the endogenous myo-2 gene by antibody staining. The rationale for this approach __48__ as follows. In wild-type C. elegans, che-22 __49__ expressed exclusively in pharyngeal muscle, whereas it __50__ expression of the pharyngeal muscle-specific myosin heavy chain gene myo-2. However, ectopic expression of che-22 in body wall muscle __51__ expression of myo-2. Because myo-2 __52__ normally never expressed in body wall muscle, this extopic expression assay provides a sensitive test for che-22 function. We __53__ two transgenic lines expressing an nkx2.5 cDNA under the control of the unc-54 body wall muscle-specific promoter. In both lines, we __54__ myo-2 expression in the body wall muscles (Fig. 1 A and B). These results __55__ that nkx2.5 can function like che-22 to induce myo-2 expression.41.A. can function B. could function C. can have functioned D. could have functioned42.A. express B. expressed C. have expressed D. had expressed43.A. was B. is C. has been D. had been44.A. is B. was C. had been D. has been45.A. activates B. activated C. has activated D. had activated46.A. could activate B. can activate C. could have activated D. can have activated47.A. was B. has been C. had been D. is48.A. generate B. have generated C. had generated D. generated49.A. detected B. detect C. have detected D. had detected50.A. showed B. show C. had shown D. have shownPart IIIDirections: Choose the one that best fits into the Discussion Section from the four choices marked A, B, C or D.DISCUSSIONThe p8 gene is barely expressed in NP but is overexpressed in acute pancreatitis (4, 12) . It is also strongly __56__ in pancreatic development and regeneration (4) . We have demonstrated that p8 is overexpressed in PC in the__57__ study. The characteristic expression of p8 is mainly attributable to its mitogenic activity (5) .__58__, p8 expression in PC would not be cancer-specific. __59__, it should be clarified whether p8 overexpression in PC is simply attributable to the excessive growth activity of cancer cells or to some genetic change(s), such as mutations.We __60__ the correlation between p8 overexpression and various clinicopathological parameters in PC. Larger tumors (>2 cm) showed a significantly higher overexpression rate of p8, and less differentiated types, advanced stages, and cases characterized by shorter survival tended to show p8 overexpression. These results also reflect the mitogenic activity of p8.__61__ reports (4, 5) have shown that p8 expression is induced by various proapoptotic __62__. It is suggested that p8 has an anti-apoptotic function (4, 5) . The significance of apoptosis in cancer cells is controversial. High spontaneous apoptosis is __63__ to be correlated with poor prognosis in PC (13) . If p8 has anti-apoptotic activity, p8 overexpression in PC cells would lead to resistance against apoptosis. Although we have not demonstrated the relationship between p8 and apoptosis in PC, the tendency toward shorter survival in p8-overexpressing cases is not __64__ with the past report (13) . It should be investigated whether p8 promotes PC cell growth through its anti-apoptotic activity.It is __65__ that p8 is a DNA-binding protein. As a transcriptional factor, it has a role in some phosphorylation/dephosphorylation signal pathways that involve its translocation to the nucleus and specific binding to DNA (4) . Potentially, p8 is phosphorylated by various kinases (4, 5) . Recent reports (14) showed that some kinases, such as the phosphatidylinositol 3-kinase or extracellular signal-regulated kinase, lead to inappropriate pancreatic cellular proliferation. Genetic mutations of K-ras, p16, and p53 in PC lead to cellular proliferation __66__ the phosphatidylinositol 3-kinase and/or the extracellular signal-regulated kinase pathways (14) . It is to be examined whether there is p8mutation in PC and how p8 participates in kinase signaling pathways.Recently, candidate of metastasis-1, a __67__ factor in human breast cancer, was identified (15) . Interestingly, p8 is structurally similar to candidate of metastasis-1 (15) . p8 might be __68__ in cancer metastasis, however, we could not find a significant difference in p8 expression between primary and metastatic lesions in our study. The relationship between p8 expression and cancer metastasis needs to be studied further.In __69__, we have demonstrated the overexpression of p8 in human pancreatic cancer. Our results suggest that p8 participates in the __70__ of pancreatic cancer, which reflects its mitogenic activity.51.A. induced B. reduced C. introduced D. seduced52.A. current B. / C. present D. former53.A. Thereafter B. Subsequently C. Additionally D. Therefore54.A. But B. Similarly C. However D. Consequently55.A. researched B. investigated C. discussed D. detected56.A. Previous B. Other C. Published D. Numerous57.A. stimuli B.stimulants C. stimulations D. simulations58.A. reported B. hypothesized C. concluded D. analyzed59.A. similar B. resilient C. consistent D. identical60.A. suggested B. confirmed C. recommended D. proposed61.A. via B. viz C. on D. along62.A. fresh B. risk C. novel D. contributing63.A. resolved B. dissolved C. immersed D. involved64.A. summarization B. summary C. end D. all65.A. attack B. onset C. development D. appearance Part IVDirections: Translate into English the Chinese phrases given in the brackets to complete the preceding sentences.1.After controlling for age, sex, race, preexisting coronary heart disease, mean arterial blood pressure,diabetes, glucose level, cholesterol level, smoking, body mass index, and study site, the presence of retinopathy____________. (与慢性心力衰竭发病危险增加2倍有关)2.Maximum mean relative enhancement ratio and mean slope of relative enhancement of lung cancerpatients____________. (明显低于健康人)3.____________ receive either alendronate (10 mg per day) or calcitriol (0.5 μg per day) a mean(±SD) of 21±11 days after transplantation. (149例病人被随机分组)4.These results establish Nrg4 as a brown fat–enriched endocrine factor ____________, includingtype 2 diabetes and nonalcoholic fatty liver disease (NAFLD). (对治疗肥胖相关疾病具有潜在作用)5.____________ reported GSPE strongly decreased NO and iNOS expression by LPS-stimulatedmacrophages. （我们的研究成果与Houde 等人之前所做的研究一致）6.Among 988 patients with gastric cancer, pernicious anemia ____________. (有11例原已确诊为恶性贫血)7.Background: Obesity____________. (被认为是结直肠癌发病的重要危险因素)8.The p8 was overexpressed (positive cells >25% in 1,000 cells) in 27 of 38 (71%) of PCs,____________. (而慢性胰腺炎中仅有17%)9.However, ____________.（几个小规模的临床研究结果没有产生充分证据证明抗坏血酸对铅毒性具有有益作用）10.____________.（使用长效β2激动剂大大改善了慢性阻塞性肺病患者的治疗效果）。
1.These figures boil down to no significance as they are statistically imperfect.A amount toB conform toC contribute toD attach to2.The researchers are working hard to find the optimal concentration of this drug.A most poisonousB most likelyC most famousD most desirable3.This young lawyer dares to take on the powerful on behalf of the poor and weak.A with the favor ofB find good jobs forC assume the responsibility forD accept the challenge of4.The last traces of respectability had vanished by the time he was convicted and imprisoned.A collapsedB disappearedC perishedD scattered5.Fearful of losing her job for good, this lady decided to talk to the manager directly.A for benefitsB by luckC for everD at hand.6.An important innovation in this college was the introduction of the seminary method for advanced students.A ideaB changeC matterD policy7.This archaeologist made a study of the vast area through which the Roman civilization has been propagated.A extendedB terminatedC speculatedD restricted8.The investor would suffer a lot from a television series that was heavily invested in but never came off.A was releasedB proved satisfactoryC failed completelyD won awards9.Given the gravity of the situation, the best thing we can do is to declare the company bankrupt.A gravitationB fascinationC seriousnessD incurability10.When the symptom occurs, she finds it difficult to manipulate a pencil despite her young age.A utilizeB handleC masterD dominateSection B :Directions: There are ten questions in this section. Each question is a sentence with something missing. Below each sentence are four words or phrases marked A, B , C and D. Choose one word or phrase that best completes the sentence. Mark the corresponding letter with a single bar across the square brackets on your machine-scoring Answer Sheet.11.The country once threatened to ___ diplomatic relations with its neighbor if the latter was too friendly to the rebels.A show offB keep offC break offD call off12.In English leaning, a ___ circle occurs when a student makes more errors after being scolded.A viciousB vigorousC verticalD voluntary13.Some ancient people were able to tell the time by the shadow ___by the sun on the slate.A thrownB flungC castD tossed(upward)petition compels districts to devote their limited resources to achieving results that compare ___ with other localdistricts.A significantlyB favorablyC dramaticallyD superficially15.If you don’t know how to ___ your achievements, your parting from this world is going to be a nightmar e.A take hold ofB get rid ofC let go ofD make fun of16.This country could have as many as 10 million cases of AIDS in 2010 if the ____ is not taken seriously.A episodeB epidemicC equivalentD eruption17.With a wide variety of fresh fruit ___available, canner fruit is no longer so popular as before.A willinglyB appropriatelyC confidentlyD readily =easily18.The crisis over parliamentary election illustrated the unpredictable ____that events could take once the coalition troopsare withdrawn.A processB lineC wayD course19.Decades of ___ might have been partially responsible for our ignorance of development abroad.A insulationB irrigationC integrationD isolation20.There have been some insensible people who attempt to end their pains ____ through suicide.A by and largeB once for all =foreverC heart and soulD on the wholePart II. ClozeDirections: There are 10 questions in this part of the test. Read the passage through. Then, go back and choose one suitable word or phrases marked A, B, C and D for each blank in the passage. Mark the corresponding letter of the word or phrase you have chosen with a single bar across the square brackets on your machine-scoring Answer Sheet.There is now a new keychain device that lets people turn off most TVs anywhere---- from airports to restaurants. And it is selling faster than 21 . “I thought there would just be a few sales, but we can’t 22 demand,” said inventor MitchAltman of San Fran cisco, U.S. “I didn’t know there were so many people who wanted to turn TVs off.”Hundreds of orders for Altman’s US $14.99 TV-B-Gone device poured in last week. The tiny remote control device had been 23 in Wired magazine and other online-media outlets. 24 , the unexpected attention overloaded the website of his company. Cornfield Electronics, and caused it to 25 .The keychain device works like a 26 remote control ----but it only turns TVs on or off. With a push of the button, it goes through a 27 of about 200 infrared codes that control the power of about 1,000 television models. Altman said the majority of TVs should 28 within 17 seconds. It takes a little more than a minute for the device to 29 all the trigger codes.The 47-year-old Altman got the idea for TV-B-Gone a decade ago. He was out with friends at a restaurant and they found themselves all 30 by the TV, but no one was around to turn it off.21. A expects B expectation C expected D expecting22. A give in to B hold on to C make up for D keep up with23. A acknowledged B announced C admitted D applied24. A At times B On time C Behind time D At the same time25. A clash B crush =smash C cruise D crash26. A commonplace B universal C mean D medium27. A string B flock C school D fleet28. A repel B repeat C react D reproach =blame29. A submit B permit C omit D emit30. A bothered B haunted C interrupted D hinderedPart III. Reading ComprehensiveDirections: In this part of the test, there are five short passages. Read each passage carefully, and then do the questions that follow. Choose the best answer from the four choices given and mark the corresponding letter with a single bar across the square brackets on your machine-scoring Answer Sheet.Passage OneAnimals are more like us than we ever imagined. They feel pain, they experience stress, and they show affection, excitement and love. All these finding have been made by scientists in recent years----and such results are beginning to change how we view animals.Strangely enough, this research was sponsor ed by fast food companies like McDonald’s and KFC. Pressured by animal rights groups, these companies felt they had to fund scientists researching the emotional and mental states of animals. McDonald’s, for instance, funded studies on pig behaviors at P urdue University, Indiana. This research found that pigs seek affection and easily become depressed if left alone or prevented from playing with each other. If they become depressed, they soon become physically ill. Because of this, and other similar studies, the European Union has banned the use of isolating pig stalls from 2012. In Germany, the government is encouraging pig farmers to give each pig 20 seconds of human contact a day, and to provide them with toys to prevent them from fighting.Other scientists have shown that animals think and behave like humans.Koko, the 300-pound gorilla (大猩猩)at the Gorilla Foundation in Northern California, for instance, has been taught sign language. Koko can now understand several thousand English words, more than many humans who speak English as a second language. On human IQ tests, she scores between 70 and 95.Before such experiments, humans thought language skills were absent from the animal kingdom. Other myths are also being overturned, like the belief that animals lack self-awareness. Studies have also shown that animals mourn their dead, and that they play for pleasure.These striking similarities between animal and human behavior have led some to ask a question: “If you believe in evolution, how can’t you believe that animals have feelings that human beings have?”Until recently, scientists believed that animals behaved by instinct and that what appeared to be learned behavior was merely genetically-programmed activity. But as Koko the Gorilla shows, this is not the case. In fact, learning is passed from parents to offspring far more often than not in the animal kingdom.So what implications does this knowledge have for humans? Because of this , should we ban hunting and animal testing? Should we close zoos? Such questions are being raised by many academics and politicians. Harvard and 25 other American law schools have introduced courses on animal rights.31. The author feels it strange that the research was sponsored by fast food companies like McDonald’s and KFC probably because these companies_____.。
研究生院党委研究生工作部二〇一八年八月目录一、新生信息核对和学籍电子注册 (1)（一）信息核对 (1)（二）学籍电子注册 (1)（三）注意事项 (1)二、制定培养计划 (2)三、选课 (2)（一）选课时间 (2)（二）选课流程 (2)（三）选课说明 (3)（四）选课安排 (5)（五）选课限制 (6)（六）课程免修 (6)（七）课程重修 (6)四、培养环节基本要求与“系统”应用 (7)（一）研究生培养过程流程图 (7)（二）研究生培养环节基本要求 (8)（三）“系统”中研究生培养环节相关操作 (9)（四）研究生学位论文开题论证流程图 (10)五、研究生学位论文答辩和学位申请工作流程 (11)（一）硕士研究生学位论文答辩和学位申请工作流程图 (11)（二）博士研究生学位论文盲审工作流程图 (12)（三）博士研究生学位论文答辩和学位申请工作流程图 (13)六、附录 (14)（一）2018-2019学年第一学期学术型硕士研究生公共课分班安排 (14)（二）2018-2019学年第一学期应用型硕士研究生公共课分班安排 (16)（三）2018-2019学年第一学期博士研究生公共课分班安排 (17)（四）各学院（系、所）研究生秘书联系方式 (19)（五）优质课程目录 (20)一、新生信息核对和学籍电子注册（一）信息核对9月4-7日，新生须对“研究生综合管理信息系统”（以下简称“系统”）中的个人信息进行核对和完善。
（1）新生访问“系统”（点击研究生院主页左上角“研究生综合管理信息系统”或/index.do），点击页面中下部“新生信息核对”，输入登陆账号（本人学号）和密码（本人学号）进入“系统”进行信息核对。
（2）信息核对时如发现字段信息有误，请在字段中填写正确信息；如字段信息空白，请填写字段信息。
研究生英文成绩单中姓名采用拼音，必须规范填写，填写示例：张小明，Zhang Xiaoming。
留学生“姓名拼音”填写英文名称（严禁填写中文名），便于打印英文成绩单。
2018级博士研究生公修课程安排
2018级全日制学术型硕士研究生
英语课程安排
说明：英语教材为《新视角研究生英语读说写》第二册，高等教育出版社。
2018级全日制学术型硕士研究生
教育类公修课程安排
说明：课程与教学论（外语）除外。
2018级全日制教育硕士专业学位研究生教育类公修课程安排
全日制
心理发展教育：所有学生必修，均由学校安排上课；
课程与教学论：所有学生必修。
培养方案中课程码前两位为00的由学校安排上课，课程码前两位不是00的由学院安排上课；
教育测量与评价：非所有学生必修。
培养方案中没有设置的，不用修；培养方案中有，课程码前两位为00的由学校安排上课，课程码前两位不是00的由学院安排上课。
2.全日制教育硕士研究生公共选修课程有3门：基础教育改革研究、中外教育简史、教育政策与法规，供全校全日制教育硕士研究生选修。
3.本学期全日制教育硕士公共必修课和公共选修课上课起止周为1-13周，第14周进行考试或考查；15-18周由各学院安排校内实训，第18周对校内实训进行总结和考核。
