百达扬说明书
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Mouse IFN-γprecoated ELISPOT kit(strips)Cat#:2210005产品描述:深圳市达科为生物工程有限公司生产的达优®系列ELISPOT预包被试剂盒采用原装进口高亲和力高效价抗体对,经预包被PVDF板、低温干燥、真空密封包装等工艺流程制备。
成品PVDF板上预包被的抗体分布均匀、效价稳定,2-8ºC可存放12个月。
达优®系列预包被ELISPOT试剂盒使实验检测时间从3天缩短为2天,大幅度减少无菌操作的实验步骤,减轻实验者的劳动强度和减少污染的几率。
使得实验者能够轻松、高效地完成复杂的ELISPOT检测实验。
试剂盒提供的试剂、规格:名称规格×数量Biotinylated Antibody100μL×1支Streptavidin-HRP100μL×1支Dilution Buffer R(1×)10mL×2瓶Washing Buffer(50×)15mL×1瓶AEC Dilution10mL×1瓶AEC SolutionⅠ(20×)500μL×1支AEC SolutionⅡ(20×)500μL×1支AEC SolutionⅢ(200×)50μL×1支阳性刺激物50T预包被PVDF可拆板1块实验者自备的试剂与仪器:1.RPMI-1640基础培养基(需要添加双抗)2.无血清培养基(完全培养基,即用型),推荐使用达优@ELISPOT无血清培养基。
3.超净工作台4.CO2细胞培养箱5.微量移液器及配套Tip头6.8通道微量移液器7.0.5mL,1.5mL EP管8.酶联斑点分析仪检测操作:第一天:接种细胞,加入刺激物,培养(严格注意无菌操作)试剂配制1.阳性刺激物:现配现用。
2.无血清培养基:如果没有ELISPOT无血清培养基,可用含5-10%胎牛血清的RPMI-1640培养基代替。
Mobius ®FlexReady Solution for ClarificationFast setup. Maximum adaptability. Pre-designed and optimized.Part of the Mobius FlexReady family of application-specific solutions, the Mobius FlexReady Solution for Clarification is an easy-to-use system featuring an optimized single-use flowpath designed to fully support your clarification needs. It features Millipore’s innovative, high-performance Millistak+® Pod disposable depth filters which are ideally suited for primary and secondary clarification. The Mobius FlexReady Solution for Clarification consists of single-use Flexware ™ assemblies, innovative separation devices and process-ready hardware systems to deliver optimal operational flexibility, from process development to clinical production to small-scale commercial manufacturing. The self-contained anddisposable nature of the system eliminates maintenance as well as cleaning validation requirements. Accompanied by extensive Millipore support and services, the Mobius FlexReady Solution for Clarification can help you maximize resource productivity and reduce risk.2EFFiciEnt ProcESSing FroMlab to PilotThe Mobius FlexReady Solution for Clarification is designedto process up to 250 liters of high cell density, low viabilitymammalian cell culture using Millistak+ Pod disposabledepth filters without centrifugation. Processing volumescan range up to 500L or even higher, depending uponthe feed quality and the use of the centrifuge. TheMobius solution enables clarification operations acrossa membrane area range of 0.054 m2 to 5.5 m2. The CL-1system is designed for lab scale processing, and the CL-2system efficiently manages pilot scale processing.•CL-2 system features an ergonomic cart that supportspilot scale Pod filters•Innovative low dead volume t-connectors, enabling theuse of traditional pressure transducers•Peristaltic pump with preset pressure controls•High-pressure cut-off switch ensures operator safety•Presized sterilizing-grade filter and product collectionassembly•Flexware assemblies designed to fit the hardware andinstall quickly and easilyFigure 2. Hardware system components moveand connect easily for maximum mobility.Figure 1. the filter end cart works with all MobiusFlexready Solutions for optimum equipmentutilization.MoDular, oPtiMizED DESignMobius FlexReady Solutions are ergonomically designedfor fast setup, maximum adaptability to changing processneeds and reduced operator error. Specially designedhardware conveniently holds pumps, instrumentation,filters and containers, right where you need them. Amodular, interlocking multi-cart system offers maximummobility. The filter end cart is designed to work with allMobius FlexReady Solutions, leveraging your investment incapital equipment and maximizing resource utilization.3novEl intEgratED tEcHnologiESlow Dead volume t-connectorsMobius FlexReady Systems feature Millipore’s innovative low dead volume t-connector built into the flowpath which is specifically designed for use with traditional pressure transducers. A LLDPE septum provides the barrier between the process fluid and the transducer that eliminates the need to clean sensors while eliminating the risk of contamination.SaFE anD EaSy loaDing oF Pilot ScalE PoD FiltErSThe Mobius FlexReady Solution , CL-2, for pilot scaleprocessing is uniquely designed with user safety and utility in mind. The Pod cart includes a Pod holder and extension kit, and is ergonomically designed at a convenient height to load pilot scale Pod filters. This cart also includes an easy to clean drip tray, and convenient drawer for supply storage.Millistak+ Pod Disposable Depth Filter SystemMillistak+ depth filter media is offered in a scalable, single-use format, the Pod Filter System. The Millistak+ Podsystem is ideal for a wide variety of primary and secondary clarification applications, including cell cultures, yeast and E. coli lysates post centrifuge, E. coli refolds, media, vaccines, plasma proteins and sera. Millistak+ Pod filters are available in three distinct series of media grades in order to meet your specific application needs. Millistak+ DE, CE and HC media deliver optimal performance through a gradient density matrix as well as positive surface charge properties. Although the Mobius FlexReady Solutions forclarification are designed to accommodate applications from lab to pilot, the Pod depth filter system is also scalable to process scale applications. See datasheet DS0217EN00 to learn more about Pod for process scaleapplications.Figure 3. the innovative low dead volumet-connector protects the process fluid from contami-nation.Figure 4. Ergonomic cart for easy loading of pilot scale Pod depth filters.Figure 5. Easy to clean drip tray.4StanDarDizED conFigurationS For rEliablE rESultSThe flowpath has been carefully designed and tested by our design and applications engineers, resulting in a consistent, standardized flowpath. The flexware assemblies are gamma-irradiated for low bioburden operations and include a sterilizing-grade filter for final product collection to safeguard product quality. The flowpath (See Fig. 6) consists of:• Core Flexware assemblies which includes pump tubing assembly, Pod drain & sampling assembly, filter drain line, and Pod vent line• Sterilizing-grade filter assembly for final collection with sampling containers and NovaSeal ™ Crimping Sleeve for sterile disconnect• Optional process containers for source, buffer, WFI, waste and sampling •Millistak+ Pod Disposable Depth Filter5The system is manufactured according to the ISO® 9001 quality standard. The system is designed to be compliant with CE and EN 60204. 67Collapsible Containers250L bin (holds 100L or 250L process containers)MBSACC006U 500 - 1,000L bin (holds 500L process container designed for this system)MBSACC007UContainment trays10L tray (holds 5 or 10L process containers)MBSACC005U 50L tray (holds 20L or 50L process container)MBSACC004UWeigh Scales60 kg (132.3 lbs) for CL-1 MBSACC019U 600 kg (1,328 lbs) for CL-2 MBSACC020U Display 100 -110 VAC 50/60Hz MBSACC022U Display 230VAC 50/60HzMBSACC023UorDEring inForMationAll Millistak + Pod depth filters must be purchased separately.See datasheets DS0217EN00 for ordering information.Choose from a suite of services, including installation,commissioning validation, training and annual performance review to meet your specific processing requirements. Allservices are performed by Mobius FlexReady services certified engineers.Factory Acceptance TestingSVCMBSCFAT Installation and Operational Qualification Protocol Performance Zone* 1SVCMBSCIQOQZ1Installation and Operational Qualification Protocol Performance Zone* 2SVCMBSCIQOQZ2Installation and Operational Qualification Protocol Performance Zone* 3SVCMBSCIQOQZ3Installation and Operational Qualification Protocol, CL-1DOCMBSC1IQOQ Installation and Operational Qualification Protocol, CL-2DOCMBSC2IQOQ Annual Performance Review Zone* 1SVCMBSCAPRZ1Annual Performance Review Zone* 2SVCMBSCAPRZ2Annual Performance Review Zone* 3SVCMBSCAPRZ3For flowpath drawing, see Fig. 6 on pg. 4. Consult with your sales representative to configure your Clarification flowpath using standard, optimized options.Each system has a dedicated flowpath, and the flowpath components are not interchangeable between CL-1 and CL-2. Ensure you order the flowpath for the hardware system you have selected.* For Zone and pricing information, contact your local Milliporerepresentative.The flowpath includes the NovaSeal Crimping Sleeve for sterile disconnect of sample containers. The NovaSeal Crimping Tool is sold separately. See datasheet DS1040EN00 Rev. B for ordering information.8Millipore, Mobius, Millistak+, Durapore, Opticap and Millipore Express are registered trade-marks of Millipore Corporation.ISO is a registered trademark of the International Standards Organization.Bioprene is a registered trademark of Watson-Marlow Ltd.SmartSite is a registered trademark of Cardinal Health, Inc.The M mark and Advancing Life Science Together, FlexReady, Flexware, PureFlex and NovaSeal are trademarks of Millipore Corporation.Lit. No. DS1065EN00 Rev. B 07/09 DP SBU-09-01811 Printed in U.S.A. © 2009 Millipore Corporation, Billerica, MA 01821 U.S.A. All rights reserved./mobiusto PlacE an orDEr or rEcEivE tEcHnical aSSiStancEFor additional information call your nearest Millipore office:In the U.S. and Canada, call toll-free 1-800-MILLIPORE (1-800-645-5476)In the U.S., Canada and Puerto Rico, fax orders to 1-800-MILLIFX (1-800-645-5439)Outside of North America contact your local office.To find the office nearest you: /offices Internet: Technical Service: /techservice。
【药品名称】商品名称:百达扬通用名称:注射用艾塞那肽微球英文名称:Exenatide Microspheres for Injection【成份】注射用艾塞那肽微球活性成份为艾塞那肽。
辅料:注射用艾塞那肽微球:乙交酯丙交酯共聚物(50:50),蔗糖。
注射用溶剂:羧甲基纤维素钠、氯化钠、聚山梨酯20、磷酸二氢钠一水合物、磷酸氢二钠七水合物、注射用水。
【适应症】用于改善2型糖尿病患者的血糖控制,适用于单用二甲双胍、磺脲类以及二甲双胍合用磺脲类血糖仍控制不佳的患者。
【用法用量】推荐用量注射用艾塞那肽微球(2mg)应每7天(每周)皮下注射一次。
可在一天中的任何时间注射,空腹或进食后均可。
漏用如漏用一次且距离下次预定用药至少3天以上,应在发现后尽快注射。
此后,患者可恢复其每7天(每周)一次的常规用药计划。
如漏用一次且距离下次预定用药1或2天,患者不应给予漏掉剂量而应在下次预定用药时按照常规计划注射。
改变每周用药方案如果有需要可改变每周的用药日,只要与上次注射至少间隔3天。
用法注射用艾塞那肽微球由患者自行给药,需要混合药物和填充注射器。
一旦将药物混合后,必须立即注射。
用药应在腹部、大腿或上臂区域皮下(SC)注射。
告知患者在同一区域注射时,每周选择不同的部位。
禁止静脉注射或肌肉注射。
给药前,患者应接受医疗专业人员的培训。
完整的用药说明(带图示)请参见注射用艾塞那肽微球的使用手册。
【不良反应】肾功能损害重度肾功能损害(肌酐清除率<30mL/min)或终末期肾病患者不应使用注射用艾塞那肽微球,在肾移植患者中应谨慎使用。
接受透析的终末期肾病患者,由于发生胃肠道不良反应,不能很好地耐受单剂量5μg塞那肽注射液。
由于注射用艾塞那肽微球可能引起恶心、呕吐伴一过性低血容量,故治疗可能造成肾功能损害加重。
中度肾功能损害患者(肌酐清除率30至50mL/min)使用注射用艾塞那肽微球时应谨慎。
尚未在终末期肾病或重度肾功能损害患者中研究注射用艾塞那肽微球。
百灵达中文说明书篇一:百灵达V-AMP说明书百灵达V-AMP中文说明书9V-600MA:这时插入随机附带的电源。
INPU T:这里插入吉它。
MO NO(AM P):这里是它的输出,它主要是输出给吉它音箱的后级,注意一定是后级,千万不要插入吉它音箱的前级,否则音色会变得失真、尖锐不好听。
另外它是单声道输出!STERE O(PHO NES):这里是双声道输出,一般输出给调音台,或者耳机,如果你用单声道的线插到调音台上,也合适。
另我它是立体声输出,具体用到那里,你可结合实际情况,选择。
看一下,下图,相信有一定的效果器使用常识的话,光看图也能看得明白。
演奏相关的操作校音:打开校音非常简单,两个换音色的踏板(BY PASS/TUNER),一起踏下,就打开了校音模式,把吉它音量扭打开,即可方便的校音了,这里注一下,校音使用常识,吉它琴弦的英文字母,从一弦到六弦,依次为E B GD A E,使用的时候,只要把这些弦,调成相应的英文字母,吉它的音高自然就被订准了。
如果在校音时,希望听到吉它的声音,这时可以扭动 GAI N钮,使音量达到一个合适的位置。
另外在些模式下,按住TAP键,扭动GA IN钮,可以改变我们平时常用的440H Z校音模式,除非你明白,若不知道自己在做什么,我劝你还是不要动这个钮的好。
嘎嘎嘎@@,,,按一下换音踏板,即可反回演奏状态图上红线标的,这两个踏板,就是了。
换音色:最下面两块黑色的板板,就是换音色的了,你要是不明白,就给我打电话吧,对此偶不能多说。
不知你明白了没有。
呵嘎呵嘎。
使用表情踏板:最右边的,看着能个脚上去的,能上下动的,黑色的,上面印有GEH RINGE R的LOG O的,踏板,就是表情踏板了。
可﹒晶。
ωo z o ω」「『ω=ωE Z 。
=主ω2Z ω-4J 垃r�!¥�!�S 付,a rte 仁Series DOP-100 Manual Transition Industrial Automation Headquarters Delta Electronics, Inc.AsiaDelta Electronics (Jiangsu) Ltd.Sales CompanyZhangjiagang Haina Automation Equipment Co., Ltd.No. 11, Yuefeng Road, Economic Development Zone, Zhangjiagang, Jiangsu, China (Mainland)TEL:0086-0512-******** 0086152********EMAIL:*******************www.haina-auto .c 。
mPrefaceThank you for purchasing this product. This manual provides information about the conversion from theDOP-B series HMI to the DOP-100 series HMI.This manual includes:⏹Replacement model selections⏹Project conversion steps⏹Software interface conversion and function differences⏹Print function⏹File encryption function⏹COM port conversion⏹Driver updateProduct features:Delta's all new advanced DOP-100 series HMI adopts the Cortex-A8 high-performance processorwith high-brightness and high-contrast color display, as well as providing user-friendly operationinterfaces. In response to the increasing popularity of cloud applications and smart manufacturing,the DOP-100 series HMI also supports network functions, such as FTP, e-mail, VNC remotemonitoring, NTP network timing, etc.How to use this manual:When transitioning from DOP-B to DOP-100, you can use this manual as a reference for modelselection, setup, and product usage. Please first read Chapter 1 before you start converting to theDOP-100 series HMI. You can also use the Table of Contents to quickly locate the information youneed.Delta technical services:Please consult your Delta equipment distributor or Delta Customer Service Center if you encounter any problems.(This page is intentionally left blank.)Table of ContentsReplacement Model Selection1.1 Corresponding replacement models ·····································································1-21.2 Project conversion····························································································1-3Software Interface Conversion2.1 Button············································································································2-22.1.1 Button color ······························································································2-22.1.2 Previous page ···························································································2-42.2 Security level and password ···············································································2-52.3 Multimedia······································································································2-62.4 Multi-language input ·························································································2-82.5 Printer ···········································································································2-92.6 File encryption·······························································································2-112.7 Conversion of COM port ··················································································2-132.8 Update ICD OpenGL driver ··············································································2-17(This page is intentionally left blank.)Replacement ModelSelectionThis chapter describes the steps to convert from the DOP-B series models to theDOP-100 series models.試1.1Corresponding replacement models·····················································1-21.2Project conversion ···········································································1-3Replacement Model Selection DOP-100 Series Transition Manual1.1 Corresponding replacement modelsThe DOP-100 series models support conversion from the DOP-B series models, as shown in the following table. When you use a DOP-100 series model to open a project file of the corresponding DOP-B series model, the software automatically converts it to the DOP-100 series model project. For example, if you use DOPSoft 4.0 to open a project file edited onDOP-B03S210, it automatically converts the project file to that of the corresponding modelDOP-103BQ.Compatible models indicate that the DOP-100 series models are the same as the DOP-B series models in terms of the mounting dimensions and number of COM ports. Partially compatible models indicate that the mounting dimensions are the same, but the number of COM ports is different*1, so you need to note the number of COM ports when selecting the suitable model for transition. Incompatible models indicate that there is currently no corresponding model for transition, and the compatible models will be released in Q2 2019.Note:1. In the partially compatible models, the DOP-B series has three physical COM ports, while the DOP-100series has two physical COM ports. The replacement model DOP-107IV (coming soon) forDOP-B07S415 and DOP-B07E415 has three physical COM ports.DOP -100 Series Transition Manual Replacement Model Selection1.2 Project conversionWhen you use DOPSoft 4.0 to open a DOP -B project file, the software automatically determinesif there is a corresponding compatible model or partially compatible model. If there is, the projectis automatically converted and opened on the DOP -100 series model; otherwise, a pop -upwindow prompts you to select a replacing DOP -100 series model. For example, if you use DOPSoft 4.0 to open a DOP -B03S210 project file, the software automatically converts andopens it as a DOP -103BQ project file. However, if you open a DOP -B05S111 project file,a window pops up for you to select the alternative DOP -100 series model (i.e. DOP -103BQ orDOP -107CV) because there is currently no corresponding model for transition.Replacement Model Selection DOP-100 Series Transition Manual(This page is intentionally left blank.)Software InterfaceConversionThis chapter introduces the differences between the operation interfaces and functions for the DOP-B series and the DOP-100 series.試2.1Button ···························································································2-22.1.1Button color··············································································2-22.1.2Previous page···········································································2-42.2Security level and password ·······························································2-52.3Multimedia······················································································2-62.4Multi-language input ·········································································2-82.5Printer ···························································································2-92.6File encryption················································································2-112.7Conversion of COM port ··································································2-132.8Update ICD OpenGL driver ······························································2-17Software Interface Conversion DOP-100 Series Transition Manual2-2 February, 201922.1 Button2.1.1Button colorButton fill style of the DOP-B series is fixed.DOP-100 Series Transition Manual Software Interface ConversionFebruary, 2019 2-32⏹You can select [Fixed] or [Gradient] for the button fill style on the DOP-100 series.⏹Buttons are displayed in fixed colors when a DOP-B project is converted to a DOP-100project.⏹You can then change the fill style of the button to gradient.Software Interface Conversion DOP-100 Series Transition Manual2-4 February, 201922.1.2Previous page⏹DOP-B has two separate buttons for [Goto Screen] and [Previous Page]. ⏹For DOP-B, you can only change the element function on the property window.⏹ DOP-100 integrates [Goto Screen] and [Previous Page] into one button as [Goto Screen]. ⏹For DOP-100, you can change the element function on the property window, as well as double-clicking the button element to go to the property setting window.DOP-100 Series Transition Manual Software Interface ConversionFebruary, 2019 2-522.2 Security level and password⏹For DOP-B, you do not need to enter a user account for the Security Level and Password.⏹For DOP-100, you need to enter a user account for the Security Level and Password.⏹When you open a DOP-B project with DOP-100, the Security Level and Password is thesame, meaning you only need to enter the password without a user account to log in.⏹If you prefer to switch to the DOP-100 login mode, click to change the Security Leveland Password login setting.Software Interface Conversion DOP-100 Series Transition Manual2-6 February, 20192.3 Multimedia⏹DOP-B07E415, DOP-B07E515, DOP-B08E515, DOP-B10E515, and DOP-B10E615 models have the audio output function. ⏹ Only DOP-107EG and DOP-110ES of the DOP-100 replacement models have the audio output function.⏹If you open a DOP-B project with audio function on a DOP-100 replacement model that does not support this function, the interface for the audio output function is automatically removed and the [Audio Output Setting] in the [Options] drop-down list becomes unavailable. ⏹The following figures show the difference when you open a DOP-B07E415 project on DOP-107EV.DOP-100 Series Transition Manual Software Interface Conversion2 February, 2019 2-7Software Interface Conversion DOP-100 Series Transition Manual2-8 February, 20192.4 Multi-language input⏹ The Multi-language Input function is only available on the following models: DOP-103WQ,DOP-107WV, DOP-110WS, DOP-112WX, DOP-112MX, DOP-115WX, and DOP-115MX. ⏹ You can see the Multi-language Input option on the interface for the models that support thisfunction:⏹ Currently, DOP-103WQ is the replacement model for the DOP-B series that supports theMulti-language Input function.DOP-100 Series Transition Manual Software Interface ConversionFebruary, 2019 2-922.5 PrinterThe specified printer of the DOP-B project changes to ePrinter by default when converted to a DOP-100 project.Software Interface Conversion DOP-100 Series Transition ManualThe Report List button of the DOP-B project changes to the Print Output button whenconverted to a DOP-100 project.22-10 February, 2019DOP-100 Series Transition Manual Software Interface ConversionFebruary, 2019 2-1122.6 File encryptionEncrypt files from the HMI end:⏹You can encrypt files from the HMI end with DOP-B.⏹You cannot encrypt files from the HMI end with DOP-100.Software Interface Conversion DOP-100 Series Transition Manual2Encrypt files from the computer end:⏹DOP-B uses [Enable USB updating check] to encrypt files.⏹DOP-100 uses [Create Screen Data File…] and [Create Auto Update Data File] to encryptfiles.DOP-100 Series Transition Manual Software Interface Conversion2.7 Conversion of COM portTransitioning from DOP-B to DOP-100 does not cause changes to the COM port. Only thecommunication interface switches from COM1 to COM2 when converting from DOP-B03S210and DOP-B07S410. DOP-B03S210When you set COM1 of DOP-B03S210 as RS422, it automatically converts to COM2 as RS422on DOP-103BQ.Software Interface Conversion DOP-100 Series Transition Manual 2DOP-100 Series Transition Manual Software Interface Conversion2 DOP-B07S410When you set COM1 of DOP-B07S410 as RS422, it automatically converts to COM2 as RS422on DOP-107BV.Software Interface Conversion DOP-100 Series Transition Manual 2DOP-100 Series Transition Manual Software Interface Conversion2.8 Update ICD OpenGL driverAfter compiling the DOP-100 screen, an OpenGL driver error message pops up.2Go to the following link to download the latest driver:https:///download/27484/Graphics-Intel-Graphics-Driver-for-Windows-15-65-?product=80939Software Interface Conversion DOP-100 Series Transition Manual(This page is intentionally left blank.)。
SIMPLE INSTRUMENT MANAGEMENT AND SETUPThe Polytron 5100 instrument provides a simple, menu-driven user interface for quick configuration. Identifying the status and performing routine maintenance are made easy using simple commands. It can be installed in either “d” (flameproof) or “e” (increased-safety) configurations. The local display provides complete information including measurement, status indication, and any warning messages. The analogue output also allows for easy remote monitoring of the instrument and the area where it is located.PROVEN – AND STILL IMPROVING: DRÄGER MEASUREMENT TECHNOLOGYDräger has been developing and manu-facturing sensors and gas detectors for industrial use for more than 40 years.And with each new instrument generation, we drive our measurement technology a bit further. With the Polytron 5100, you will definitely benefit from this experience and power of innovation: –durable sensors–short response times –high sensitivity –high accuracy–low sensitivity to other gases or changing ambient conditionsOPTIONAL: TWO MOUNTING SETS FOR EASY FLANGE-MOUNTINGThe housing has four mounting holes.Two different mounting sets are available for installing the Polytron 5100: a duct-mount and a pipe-mount set. This means that the transmitter can be easily installed anywhere – e.g. on a smooth wall, a pipe, or an exhaust duct.Dräger Polytron® 5100Stationary Gas Detector (EC)D -24180-2010The microprocessor-based transmitter can be equipped with various electrochemical DrägerSensors to easily detect oxygen and various toxic gases in ambient air. In addition, the Polytron® 5100 can be integrated into your facility control and safety system, thus providing additional diagnostic functions.D -52603-2012D -12417-2014Dräger Polytron® 5100Flameproof transmitter for monitoring toxic gases and oxygen.Same Design, Same Operating Principle: The Polytron 5000 SeriesThe Dräger Polytron 5100 is part of the Polytron 5000 series. All transmitters of this series have the same design and user interface,which ensures a uniform operating philosophy. For you, this means: less training required and easier maintenance.Other transmitters of the Polytron 5000 series:– D räger Polytron 5000GP (EC stationary gas detector)– D räger Polytron 5310(DSIR stationary gas detector)– D räger Polytron 5700(PIR 7000 stationary gas detector)– D räger Polytron 5720(PIR 7200 stationary gas detector)DRÄGER POLYTRON® 5000 – STATIONARY GAS DETECTOR (EC)02 |OPTIONAL: THREE RELAYS FOR CONTROLLING EXTERNAL EQUIPMENTOn request, the Dräger Polytron 5100 can be equipped with three integrated relays. This enables you to use it as an independent gas detection system with two user-adjust able concentration alarms and one fault alarm. Audio alarms, signal lights, and similar devices can thus be controlled locally – without an additio-nal cable between the transmitter and a central controller. The sensor signal can be monitored using the 4-to-20-mA signal.INTELLIGENT SENSORSThe Dräger Polytron 5100 can detect a wide variety of gases. DrägerSensors are specifically designed for the demands of round-the-clock, year-round operation. The large DrägerSensor size gives them their renowned long life and superior measurement performance. The integrated sensor memory contains all relevant sensor data. This also allows the Polytron 5100 to accept the pre-calibrated DrägerSensors. The smart DrägerSensor EC downloads the gas type, calibration data, default alarm set points, and other measurement data onto the Polytron 5100.POLYTRON 5100Using proven, advanced electrochemical DrägerSensors for the best measurement performance, the Polytron 5100 offers a great cost-performance value to the user. It adds features that were not available in the previous model: –2- or 3-wire device –10 to 30 VDC 3-wire (18 to 30 VDC 2-wire)–galvanic isolator sensor coupling –4-digit, 9-segment display, with backlight (3-wire mode only)–15 sensors available for XP operation –optional relays (3-wire mode only) –optional remote sensor mounting –increased-safety (Ex e) version availableIn addition, the Polytron 5100 can operate using the low-cost MEC sensors offered by Dräger. For more information on these sensors contact your local Dräger repre-sentative.AccessoriesAccessories for remote mount, duct or pipe mounting, and more, allow for use in a wide variety of applications.FURTHER ADVANTAGES:–Easy and cost-effective: one-person calibration –Quick and easy wiring–Available as flameproof or increased safety version–Aluminium or 316 L stainless steel housing for the most extreme industrial conditions –Extremely user-friendly software thanks to a minimum number of menu items–Backlit display: easy to read, even in low light conditions. –Traffic light status indicator(green = no danger, yellow = error, flashing red = gas alarm)–Intelligent sensors for predictive maintenance–User-adjustable measuring ranges (within permitted ranges)–Matrix display allows the flexible setting of measuring ranges and unitsDRÄGER POLYTRON 5100UNIT CONFIGURED WITH DOCKING STATION FOR “E” INSTALLATION (INCREASED SAFETY)D -15037-2010DRÄGER POLYTRON® 5000 – STATIONARY GAS DETECTOR (EC)| 03TECHNICAL DATADRÄGER POLYTRON® 5100Type Flameproof “d” or combined increased-safety “d/e” transmitterGases Toxic gases and oxygen (depending on the sensor used)Measuring ranges User-adjustable (see sensor data sheet)Display Backlit 4-digit LCD; 3 status LEDs (green/yellow/red)Electrical data Analogue signal output Normal operation4-to-20-mAMaintenance Steady 3.4 mA or 3 to 5 mA 1 Hz modulation;user-selectableFault< 1.2 mA, 3-wire (< 3 mA, 2-wire)Supply voltage10 to 30 V DC, 3-wire (18 to 30 V DC, 2-wire)Relay rating (option) 2 alarms, 1 fault relay, SPDT1 A to 5 A @ 230 VAC, 0.1 A to 5 A @ 30 VDC, 0 resistive loadAmbient conditions Temperature-40 to +150 °F / -40 to +65 °C(see sensor data sheet)Pressure20.7 to 38.4 inch Hg / 700 to 1,300 mbarHumidity0 to 100% RH, non-condensingEnclosure Transmitter housing Epoxy-coated copper-free aluminiumor 316L stainless steelSensor housing PolyamideEnclosure rating NEMA 4× & 7, IP65/66/67Cable entry3/4" NPT female conduit or M20 cable glandSize (l × w × d, approx.)without Docking Station11.0" × 5.9" × 5.1" / 280 × 150 × 130 mmwith Docking Station11.0" × 7.1" × 7.5" / 280 × 180 × 190 mmWeight (approx.)without Docking Station,aluminium6.6 lbs / 3.0 kgwithout Docking Station,316 stainless steel11.0 lbs / 5.0 kgwith Docking Station,aluminum9.9 lbs / 4.5 kgwith Docking Station,316 stainless steel14.3 lbs / 6.5 kgApprovals *)UL Class I, Div 1, Groups A, B, C, D;Class II, Div 1, Groups E, F, GClass I, Zone 1, Group IIC; T-Code T6 / T4CSA Class I, Div 1, Groups A, B, C, D;Class II, Div 1, Groups E, F, GClass I, Zone 1, Group IIC; T-Code T6 / T4IECEX Ex d [ia] IIC T6/T4 Gb, -40 ≤ Ta ≤ +40/+70 °C;“d” versionEx de [ia] IIC T6/T4 Gb, -40 ≤ Ta ≤ +40/+70 °C;“e” versionEx tb [ia] IIIC T135 °C DbATEX II 2G Ex d [ia] IIC T6/T4 Gb, -40 ≤ Ta ≤ +40/+70 °C;“d” versionII 2G Ex de [ia] IIC T6/T4 Gb, -40 ≤ Ta ≤ +40/+70 °C;“e” versionII 2D Ex tb [ia] IIIC T135 °C DbCE markings ATEX (Directive 94/9/EC)Electromagnetic Compatibility (Directive 2004/108/EC)Low Voltage (Directive 2006/95/EC)*)All “e” versions are only ATEX- / IECEX-approved.DRÄGER POLYTRON® 5000 – STATIONARY GAS DETECTOR (EC)04 |DrägerSensorsPH 3/AsH 3 68 09 695NO 2 68 09 655O 2 LS 68 09 630H 2S HC 68 09 710Cl 2 68 09 665H 2O 2 LC 68 09 705NH 3 HC 68 09 645OV1 68 10 740CO 68 09 605H 2S 68 10 435NO LC 68 09 625SO 2 68 09 660H 2S LC68 09 610NH 3 LC68 09 680H 268 09 685ORDER INFORMATIONDRÄGER POLYTRON® 5100Aluminium “d”SS316L “d”Aluminium “e”SS316L “e”Without relays 45 44 86045 44 86245 44 124 *)45 44 126 *)With relays 45 44 12145 44 12345 44 125 **)45 44 127 **)*) Order Docking Station 68 12 420 for power-only wires separately.**) Order Docking Station 68 12 275 for power and/or relay wires separately.Magnetic wand for menu access (blue body, white logo)45 44 101Docking Station power-only version (includes 1 cable gland) / Docking Station68 12 420Docking Station Power, Relay and/or Remote version (includes 2 cable glands) / Docking Station 68 12 275Cable Gland for use with Docking Station 68 12 868Pipe Mount Kit 45 44 198Duct Mount Kit68 12 725Duct Mount Adapter for Remote EC Sensing Head 83 17 617EC Sensing Head Remote w/ mount kit 68 12 684MEC Sensor Adapter68 12 695IR Connection Kit Polytron® 5000/8000 Series 45 44 197PolySoft Configuration Software83 23 405Connection cable w/ plug for Remote EC Sensing Head 16 ft / 5 m 49 ft / 15 m 98 ft / 30 m83 23 305 83 23 315 83 23 330AccessoriesSplash guard68 12 510Calibration Adapter PE (with hose)45 09 314Calibration Adapter PE (without hose)68 06 978Calibration Adapter Viton®68 10 536Viton® is a registered trademark of DuPont.90 45 996 | 15.02-1 | C o m m u n i c a t i o n s & S a l e s M a r k e t i n g | P P | L E | P r i n t e d i n G e r m a n y | C h l o r i n e -f r e e – e n v i r o n m e n t a l l y c o m p a t i b l e | S u b j e c t t o m o d i f i c a t i o n s | © 2015 D r äg e r w e r k A G & C o . K G a A。
百灵达DCX2496中文说明书2、控制元件1、DCX - 2496 提供6 段的?號指示LED 供A、B、C 三組輸入端做調整用。
2、最上端的?號LED 指示CLIP過載的?號。
3、最下端的?號LED 指示MUTE靜音動作開起的指示。
4、三組輸入端的功能選擇按健,可各自調整Delay 的時間及觀看輸入的路由。
5、功能顯示板,提供所有選取欲調整___的頁面功調整指示使用。
6、使用這幾個呼叫鍵,將DCX -2496 的內部功能呼叫出?硪怨?更改,包括系統的設定、儲存、調整等。
7、頁面章?選擇鍵,就是當呼叫出?淼娜我唤M功能頁面後,再利用此選擇鍵去選取要修改的位置。
8、頁面章?參數個別調整鍵。
9、參數調整飛梭。
10、確認鍵OK、CANCEL 參數確定。
11、PCMCIA 卡及插槽( PCMCIA card slot ) 可將資料儲存於卡上,日後供呼叫及更改。
PCMCIA ( Personal ComputerMemory Card InternationalAssociation ) 是一個成立於1989 年的國際性組織目前已有超過300 個以上的會員同時在運作。
其主要的目的是建立一個省電、小體積的整合性電子卡片的標準。
在1991 年的時候,PCMCIA 推出了第一個適用於這個標準的產品記憶卡。
在這個同時,68 pin 的規格也同時的。
被確定下?砹恕?DCX - 2496 電子卡是使用“5 V12、1 - 6 聲道輸出指示,每一波段的?號指示LED 內包括MUTE、CLIP 及LIMITER 限制動作的LED 指示。
13、最上端的?號LED 指示CLIP 。
過載的?號。
14、LIMITER 電平限制指示LED,當你設定了LIMITER 參數後,輸出的電平量若到達所設定的位置時,LIMITER 指示燈即會___亮起。
15、最下端的?號LED 指示MUTE 靜音動作開起的指示。
16、輸出端功能選擇鍵,利用此功___能鍵?磉x取MUTE 的動作,或進入另一個調整頁面。
百达扬说明书 Prepared on 22 November 2020【药品名称】商品名称:百达扬通用名称:注射用艾塞那肽微球英文名称:Exenatide Microspheres for Injection【成份】注射用艾塞那肽微球活性成份为艾塞那肽。
辅料:注射用艾塞那肽微球:乙交酯丙交酯共聚物(50:50),蔗糖。
注射用溶剂:羧甲基纤维素钠、氯化钠、聚山梨酯20、磷酸二氢钠一水合物、磷酸氢二钠七水合物、注射用水。
【适应症】用于改善患者的血糖控制,适用于单用二甲双胍、磺脲类以及二甲双胍合用磺脲类血糖仍控制不佳的患者。
【用法用量】推荐用量注射用艾塞那肽微球(2mg)应每7天(每周)皮下注射一次。
可在一天中的任何时间注射,空腹或进食后均可。
漏用如漏用一次且距离下次预定用药至少3天以上,应在发现后尽快注射。
此后,患者可恢复其每7天(每周)一次的常规用药计划。
如漏用一次且距离下次预定用药1或2天,患者不应给予漏掉剂量而应在下次预定用药时按照常规计划注射。
改变每周用药方案如果有需要可改变每周的用药日,只要与上次注射至少间隔3天。
用法注射用艾塞那肽微球由患者自行给药,需要混合药物和填充注射器。
一旦将药物混合后,必须立即注射。
用药应在腹部、大腿或上臂区域皮下(SC)注射。
告知患者在同一区域注射时,每周选择不同的部位。
禁止静脉注射或肌肉注射。
给药前,患者应接受医疗专业人员的培训。
完整的用药说明(带图示)请参见注射用艾塞那肽微球的使用手册。
【不良反应】肾功能损害重度肾功能损害(肌酐清除率<30mL/min)或终末期肾病患者不应使用注射用艾塞那肽微球,在肾移植患者中应谨慎使用。
接受透析的终末期肾病患者,由于发生胃肠道不良反应,不能很好地耐受单剂量5μg塞那肽注射液。
由于注射用艾塞那肽微球可能引起恶心、呕吐伴一过性低血容量,故治疗可能造成肾功能损害加重。
中度肾功能损害患者(肌酐清除率30至50mL/min)使用注射用艾塞那肽微球时应谨慎。
尚未在终末期肾病或重度肾功能损害患者中研究注射用艾塞那肽微球。
已有使用艾塞那肽出现肾功能改变的上市后报告(包括血清肌酐升高、肾功能损害、慢性肾衰加重和急性肾衰),有时需要进行血液透析或肾移植。
其中有些事件发生在接受一种或多种已知会影响肾功能或脱水状态的药物(例如血管紧张素转化酶抑制剂、非甾体抗炎药和利尿剂)的患者中。
有些事件发生在出现恶心、呕吐或腹泻(伴或不伴脱水)的患者中。
在给予支持治疗并停用可能为诱因的药物(包括艾塞那肽)后,观察到许多病例的肾功能改变是可逆的。
在临床前或临床研究中未发现艾塞那肽具有直接肾毒性。
胃肠道疾病尚未在严重胃肠道疾病(包括胃轻瘫)患者中进行艾塞那肽研究。
患者在使用艾塞那肽时通常可出现胃肠道不良反应,包括恶心、呕吐和腹泻。
不推荐有严重胃肠道疾病的患者使用注射用艾塞那肽微球。
免疫原性患者在接受注射用艾塞那肽微球治疗后可能出现艾塞那肽抗体。
在6项为期24-30周的注射用艾塞那肽微球对照药物研究中,有5项测定了注射用艾塞那肽微球治疗患者的抗艾塞那肽抗体。
在6%接受注射用艾塞那肽微球治疗的患者中,抗体形成与血糖反应减弱有关。
如血糖控制疗效降低或未能达到血糖控制目标,应考虑其它降糖治疗【禁忌】甲状腺髓样癌:有甲状腺髓样癌(MTC)个人或家族史患者或有多发性内分泌腺瘤病2型(MEN 2)患者禁用注射用艾塞那肽微球。
超敏反应:既往对艾塞那肽或注射用艾塞那肽微球任何组分有严重超敏反应的患者禁用注射用艾塞那肽微球。
【注意事项】甲状腺C细胞肿瘤的风险注射用艾塞那肽微球禁用于有MTC个人史或家族史的患者或患有MEN 2的患者。
告知患者使用注射用艾塞那肽微球时有发生甲状腺髓样癌的潜在风险,同时让患者知晓甲状腺肿瘤相应的症状(如颈部肿块、吞咽困难、呼吸困难、持续声嘶)。
接受注射用艾塞那肽微球治疗的患者中,为早期发现MTC而进行常规血清降钙素监测或甲状腺超声的价值尚不确定。
因为甲状腺疾病的高发生率以及血清降钙素检测对MTC的低特异性,所以不必要的监测可能增加风险。
血清降钙素显着升高可能提示MTC的发生,并且通常MTC患者的降钙素值>50ng/L。
如果测量血清降钙素并发现升高,患者应交由医生做进一步评价。
在体格检查或颈部影像学检查发现有甲状腺结节的患者,也应由医生做进一步评价。
急性胰腺炎根据上市后数据,急性胰腺炎包括致死性和非致死性出血或坏死性胰腺炎的发生与使用艾塞那肽有关。
开始使用注射用艾塞那肽微球后,仔细观察患者是否有胰腺炎的体征和症状(包括持续性重度腹痛,有时放射至背部,可能伴或不伴呕吐)。
如怀疑胰腺炎,应及时停用注射用艾塞那肽微球并进行适当处理。
如确诊胰腺炎,则不应重新开始注射用艾塞那肽微球治疗。
有胰腺炎史的患者应考虑除注射用艾塞那肽微球外的其他降糖治疗。
低血糖(联合使用胰岛素促分泌药物或胰岛素时)当艾塞那肽联合胰岛素促分泌药物(如磺脲类)或胰岛素时会增加低血糖风险。
患者可能要减少胰岛素促分泌药物或胰岛素的剂量,从而降低低血糖风险。
肾功能损害重度肾功能损害(肌酐清除率<30mL/min)或终末期肾病患者不应使用注射用艾塞那肽微球,在肾移植患者中应谨慎使用。
接受透析的终末期肾病患者,由于发生胃肠道不良反应,不能很好地耐受单剂量5μg塞那肽注射液。
由于注射用艾塞那肽微球可能引起恶心、呕吐伴一过性低血容量,故治疗可能造成肾功能损害加重。
中度肾功能损害患者(肌酐清除率30至50mL/min)使用注射用艾塞那肽微球时应谨慎。
尚未在终末期肾病或重度肾功能损害患者中研究注射用艾塞那肽微球。
已有使用艾塞那肽出现肾功能改变的上市后报告(包括血清肌酐升高、肾功能损害、慢性肾衰加重和急性肾衰),有时需要进行血液透析或肾移植。
其中有些事件发生在接受一种或多种已知会影响肾功能或脱水状态的药物(例如血管紧张素转化酶抑制剂、非甾体抗炎药和利尿剂)的患者中。
有些事件发生在出现恶心、呕吐或腹泻(伴或不伴脱水)的患者中。
在给予支持治疗并停用可能为诱因的药物(包括艾塞那肽)后,观察到许多病例的肾功能改变是可逆的。
在临床前或临床研究中未发现艾塞那肽具有直接肾毒性。
胃肠道疾病尚未在严重胃肠道疾病(包括胃轻瘫)患者中进行艾塞那肽研究。
患者在使用艾塞那肽时通常可出现胃肠道不良反应,包括恶心、呕吐和腹泻。
不推荐有严重胃肠道疾病的患者使用注射用艾塞那肽微球。
免疫原性患者在接受注射用艾塞那肽微球治疗后可能出现艾塞那肽抗体。
在6项为期24-30周的注射用艾塞那肽微球对照药物研究中,有5项测定了注射用艾塞那肽微球治疗患者的抗艾塞那肽抗体。
在6%接受注射用艾塞那肽微球治疗的患者中,抗体形成与血糖反应减弱有关。
如血糖控制疗效降低或未能达到血糖控制目标,应考虑其它降糖治疗。
超敏反应已有接受艾塞那肽治疗患者发生严重超敏反应(如过敏反应和血管水肿)的上市后报告。
如果发生超敏反应,患者应停用注射用艾塞那肽微球和其他可疑药物并立即就医。
注射部位反应上市后安全性监测数据已报告使用注射用艾塞那肽微球时会出现伴或不伴皮下结节的严重注射部位反应(如脓肿、蜂窝织炎、坏死)。
个别患者需进行手术干预治疗。
大血管事件风险尚没有临床研究结论显示使用注射用艾塞那肽微球可以降低发生大血管病变的风险。
中止治疗中止治疗后,注射用艾塞那肽微球的作用可能继续,因为血浆艾塞那肽水平下降需10周。
因此应考虑选择其他药物并进行剂量选择,因为不良反应可能继续,有效性可能至少部分持续直到艾塞那肽水平下降。
【特殊人群用药】儿童注意事项:尚未确定注射用艾塞那肽微球在儿童患者中的安全性和有效性。
不推荐儿童患者使用。
妊娠与哺乳期注意事项:注射用艾塞那肽微球尚无妊娠妇女的足够资料和良好的对照临床研究。
在大鼠主要器官的形成期给予母体注射用艾塞那肽微球,出现胎鼠生长迟滞和与母体效应有关的骨骼骨化缺陷;注射用艾塞那肽微球在大鼠中没有致畸性。
在动物发育研究中,注射用艾塞那肽微球的活性成分艾塞那肽引起腭裂、不规则骨骼骨化和新生鼠死亡数增加。
因此,只有当注射用艾塞那肽微球对胎儿的潜在益处大于潜在风险时,才考虑妊娠期间使用。
老人注意事项:在5项24-30周药物对照研究中,已在132例(%)≥65岁的患者和20例≥75岁的患者中对注射用艾塞那肽微球进行研究。
这些老年患者和年轻患者间没有观察到安全性(N =152)和疗效(N =52)的差异,但是由于≥75岁的患者样本量较小,因此尚未得出其它结论。
由于老年患者的肾功能下降更常见,所以在老年患者中开始注射用艾塞那肽微球治疗时应谨慎。
【药物相互作用】对乙酰氨基酚在注射用艾塞那肽微球治疗(每周2mg)14周后给予1000mg对乙酰氨基酚片(空腹或进食时服用),未观察到对乙酰氨基酚AUC与对照期相比出现显着变化。
对乙酰氨基酚Cmax降低16%(空腹)和5%(进食),Tmax从对照期的大约1小时增加为小时(空腹)和小时(进食)。
已经对艾塞那肽注射液与以下药物的相互作用进行了研究。
预计注射用艾塞那肽微球的潜在药物相互作用与艾塞那肽注射液相似。
地高辛口服地高辛(每日一次)30分钟前,合用重复剂量的艾塞那肽注射液,可降低地高辛的Cmax 降低17%,Tmax延迟了约小时;但总体稳态药代动力学暴露量(如AUC)无改变。
洛伐他汀与单独服用洛伐他汀相比,洛伐他汀(40mg、单剂量)口服给药前30分钟给予艾塞那肽注射液(10μg每日二次),使洛伐他汀AUC和Cmax分别降低约40%和28%,Tmax延迟约4小时。
在一项为期30周的艾塞那肽注射液对照临床研究中,已服用HMG-CoA还原酶抑制剂的患者使用艾塞那肽注射液,对血脂水平与基线相比无相应的改变。
赖诺普利在服用恒定剂量赖诺普利(5-20mg/天)的轻、中度高血压患者中,合用艾塞那肽注射液(10μg每日二次)不改变赖诺普利稳态Cmax或AUC,Tmax延迟2小时。
患者24小时平均收缩和舒张压没有改变。
口服避孕药在健康女性受试者中进行了艾塞那肽注射液(10μg每日二次)对单剂量和多剂量口服避孕药联用(30μg炔雌醇加150μg左炔诺孕酮)的影响的研究。
与单独服用口服避孕药相比,在艾塞那肽注射液给药后30分钟重复给予口服避孕药(OC),炔雌醇和左炔诺孕酮的Cmax分别下降45%和27%,炔雌醇和左炔诺孕酮的Tmax分别延迟了小时和小时。
与单独给予OC相比,艾塞那肽注射液给药1小时前每日重复给予OC,炔雌醇平均Cmax降低15%,但左炔诺孕酮的平均Cmax无显着变化。
对于这两种方案,艾塞那肽注射液不改变每日重复给予口服避孕药后左炔诺孕酮的平均谷浓度。
但是,与单独给予OC相比,艾塞那肽注射液注射后30分钟给予OC,炔雌醇的平均谷浓度升高20%。
在此项研究中,食物对OC可能的影响干扰了艾塞那肽注射液对OC药代动力学的影响。