a biomedical wireless sensor network to support healthcare delivery for the elderly and chronically
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Rev. 0.1 9/10Copyright © 2010 by Silicon LaboratoriesAN539AN539EZM AC ®PRO O VERVIEW1. IntroductionThis application note gives a general overview of wireless networks and network protocols. It introduces EZMacPRO (EZHop), describes how the protocol stack fits into the wireless network, and addresses some of the standard questions raised when implementing a protocol stack, such as:⏹What is a wireless sensor network?⏹What are the EZMacPRO and EZHop software modules?2. Wireless NetworksA wireless sensor network is a collection of inexpensive computational nodes that can measure local conditions or environmental parameters and send that information wirelessly to a central location for the appropriate manipulation by the main application node. Typically, wireless sensor nodes sense variables, such as the environment, or perform basic data processing and then transmit the result or data to a central data collection node. Sensor networks are common with many applications in many different markets, including:⏹Health Applications● Remote monitoring of physiological data● Tracking and monitoring doctors and patients inside a hospital● Drug administration● Elderly assistance⏹Home Applications● Home automation● Instrumented environments● Automated meter reading⏹Commercial Applications● Environmental control in industrial and office buildings● Inventory control● Vehicle tracking and detection● Traffic flow surveillance⏹Military Applications● Monitoring friendly forces● Battlefield surveillance● Targeting● Nuclear, biological, and chemical attack detection⏹Environmental Applications● Forest fire detection● Flood detectionAN5392Rev. 0.13. Network ProtocolsThe network communication protocol is a well structured software stack designed to ensure that the appropriate data reaches its destination with minimal lost data packets. Most communication protocols are structured as suggested by the Open Systems Interconnection (OSI) reference model. The OSI model divides the communication system into layers, with each layer serving a specific purpose.The OSI defines the purpose and working architecture of each layer and then makes recommendations for the interactions between layers. The layer structure consists of seven individual layers as shown in Figure 1.Figure1.OSI Model⏹Physical Layer● Delimits and encodes the bits onto the physical medium● Defines electrical, mechanical, and procedural formats⏹Data Link Layer● Transfers data units from one network node to another over the transmission circuit● Ensures data integrity between nodes⏹Network Layer● Routes and relays data units across a network of nodes● Manage flow control and call establishment procedures⏹Transport Layer● Ensures end-to-end data transfer and integrity across the network● Assembles (and breaks into smaller portions) packets for routing by Layer 3⏹Session Layer● Coordinates connection and interaction between applications● Establishes dialogue; manages and synchronizes direction of data flow⏹Presentation Layer ● Negotiates syntactic representation and performs data transformation, compression, and code conversation ⏹Application Layer● Applications and application interfaces for OSI networks● Provides access to lower layer functions and servicesNot all layers of the OSI reference model need to be implemented since, in certain implementations, layers may be combined or omitted depending on the complexity of the application. Such simplifications of the OSI model are essential in small embedded wireless sensor networks where system resources in the embedded MCU are limited or the cost of wireless nodes is critical. A classic example of this consideration can be seen when comparing proprietary type networks to standards-based networks. For example, standards-based ZigBee stacks can reach memory requirements of 128k whereas proprietary based stacks, such as those based upon EZMac, may only reach 10k.AN539Rev. 0.134. The EZMacPRO and EZHop Software Modules Position in the OSI Model EZMacPRO and EZHOP software modules are designed to only contain the low-level functions according to the OSI model, and their implementation provides the two lowest layers: the Physical and the Data Link layer. This design allows EZMac to satisfy the needs of most network designers.This implementation allows Silicon Laboratories to provide the common layers as a starting place upon which customers can write higher layers where the design can be best optimized for their application. EZMacPRO/EZHop use a common, well-defined API enabling designers to easily add these higher level layers.As designers learn about network implementation, they often decide that simpler, smaller networks do not require these additional layers, and the network structure can be represented by the model demonstrated in Figure 2. In this case, the two lower layers are implemented using EZMac and EZHOP and the Application Layer is similar to that used in wired or infra-red implementations.Figure2.Protocol Scheme with EZMac and EZHOPDesigners wanting to see an example of a simple star network implementation (where network forming and network management are implemented in the application layer) may wish to review the EZMac Programming Guide for further details.AN5394Rev. 0.15. EZMacPRO and EZHop Software ModulesEZMacPRO and EZHop solutions are wireless communication software modules for embedded systems using the EZRadioPRO-based radio. Both EZMacPRO and EZHop are implemented as a single-source code. They have the same programming interface (API) serving the same OSI layers; however, they are designed for very different and specific applications.The EZHop module is a frequency-hopping module designed to provide up to 50 individual channels for communication. It is primarily designed for applications that must meet FCC Part 15 Section 247 in order to transmit at high powers (above –1.2dBm).According to the FCC requirement for frequency hopping systems operating in the 902–928MHz band, if the +20dB bandwidth of the hopping channel is less than 250kHz, the system must use at least 50 hopping frequencies. The maximum allowed +20dB bandwidth of the hopping channel is 500kHz.In systems where high output power can be used without the need for compliance to FCC regulations, such as in applications aimed at meeting the ETSI regulations in Europe, the standard implementation of the EZMacPRO stack without the EZHop routines is a good choice.The standard implementation of EZMacPRO supports frequency hopping of up to four channels to increase the robustness of communication. Robustness is increased because the likelihood of all channels being blocked by other transmitters is vastly reduced. The reduction of channels makes the system more power efficient because the transmitted packets contain fewer preamble bytes. In addition, the use of fewer channels makes it possible to implement additional features without adding timing complexity to the stack. This makes feature implementation easier and more robust (e.g., auto transmit on all channels, antenna diversity, etc.).EZMacPRO and EZHop solutions transmit and receive data in short packets via an RF link in the ISM band. These routines run as background tasks (two interrupt service routines) on the main application microcontroller. No part of the MAC engine is run in the foreground loop; so, it can be used exclusively for the embedded application.The EZMacPRO module supports a wide range of addressing modes, packet filtering modes, collision, and error-detection schemes. Additionally, the EZMacPRO module provides a built-in acknowledgement and packet forwarding feature. The EZMacPRO module is also compatible with earlier versions of EZMac, which were designed to support the EZRadio family of devices.EZHop additionally supports a wide range of addressing modes, packet filtering modes, and collision detection with the built-in acknowledgement and packet-forwarding feature while implementing an advanced frequency search mechanism used to find valid packets during the receive process.By design, EZMacPRO and EZHop are intended for small networks and are used to easily build peer-to-peer or star networks. The node count is 255 per subset with a maximum subset count of 255. The EZMacPRO and EZHop routines are designed to be used in low-node-count wireless networks to specifically avoid the need for a network management feature, thus, again, avoiding the cost overhead of processing, memory, and power requirements. If larger networks are required, users can add this layer above the standard EZMac layers.Both EZMacPRO and EZHop solutions can theoretically support mesh networking; however, this network topology is not coded into the current implementation of the EZMac stack. The current stack provides no network organization or self-healing feature since the large majority of applications do not require them, and minimal processing, power, and memory requirements are key.EZMacPRO and EZHop support transmitter, receiver, and transceiver devices from the EZRadioPRO family. To optimize code size for a given application, some features can be disabled before the compilation of source code.AN539Rev. 0.15N OTES :AN5396Rev. 0.1C ONTACT I NFORMATIONSilicon Laboratories Inc.400 West Cesar ChavezAustin, TX 78701Tel: 1+(512) 416-8500Fax: 1+(512) 416-9669Toll Free: 1+(877) 444-3032Please visit the Silicon Labs Technical Support web page:https:///support/pages/contacttechnicalsupport.aspxand register to submit a technical support request.Silicon Laboratories and Silicon Labs are trademarks of Silicon Laboratories Inc.Other products or brandnames mentioned herein are trademarks or registered trademarks of their respective holders.The information in this document is believed to be accurate in all respects at the time of publication but is subject to change without notice. Silicon Laboratories assumes no responsibility for errors and omissions, and disclaims responsibility for any consequences resulting from the use of information included herein. Additionally, Silicon Laboratories assumes no responsibility for the functioning of undescribed features or parameters. Silicon Laboratories reserves the right to make changes without further notice. Silicon Laboratories makes no warranty, rep-resentation or guarantee regarding the suitability of its products for any particular purpose, nor does Silicon Laboratories assume any liability arising out of the application or use of any product or circuit, and specifically disclaims any and all liability, including without limitation conse-quential or incidental damages. Silicon Laboratories products are not designed, intended, or authorized for use in applications intended to support or sustain life, or for any other application in which the failure of the Silicon Laboratories product could create a situation where per-sonal injury or death may occur. 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Wireless Sensor Networks for In-Home Healthcare:Potential and Challenges1. Medical Applications of the FutureAdvances in wireless sensor networking have opened up new opportunities in healthcare systems. The future will see the integration of the abundance of existing specialized medical technology with pervasive, wireless networks. They will co-exist with the installed infrastructure, augmenting data collection and real-time response. Examples of areas in which future medical systems can benefit the most from wireless sensor networks are in-home assistance, smart nursing homes, and clinical trial and research augmentation. As the world's population ages [3], those suffering from diseases of the elderly will increase. In-home pervasive networks may assist residents by providing memory enhancement, control of home appliances, medical data lookup, and emergency communication.Unobtrusive, wearable sensors will allow vast amounts of data to be collected and mined for next-generation clinical trials. Data will be collected and reported automatically, reducing the cost and inconvenience of regular visits to the physician. Therefore, many more study participants may be enrolled, benefiting biological, pharmaceutical, and medical-applications research.2. Critical Development Areas2.1 Enabling Technologies for Future Medical Devices:- Interoperability: As a result of the heterogeneity present in the system, communication between devices may occupy multiple bands and use different protocols. For example, motes use unlicensed bands for general telemetry or ISM equipment. Implanted medical devices may use a licensed band allocated for that purpose by the FCC. In order to avoid interference in the increasingly crowded unlicensed ISM band, biomedical devices may use the WMTS band (wireless medical telemetry services, at 608 MHz). [1] The homecare network must provide middleware interoperability between disparate devices, and support unique relationships among devices, such as implants and their outside controllers.- Real-time data acquisition and analysis: The rate of collection of data is higher in this type of network than in many environmental studies. Efficient communication and processing will be essential. Event ordering, time-stamping, synchronization, and quick response in emergency situations will all be required.- Reliability and robustness: Sensors and other devices must operate with enough reliability to yield high-confidence data suitable for medical diagnosis and treatment. Since the network will not be maintained in a controlled environment, devices must be robust.- New node architectures: The integration of different types of sensors, RFID tags, andback-channel long-haul networks may necessitate new and modular node architectures.2.2 Embedded, Real-Time, Networked System Infrastructures for MDSS:- Patient and object tracking: Tracking can be considered at three levels: symbolic (e.g., Room 136 or X-Ray Lab); geographical (GPS coordinates of a patient on an assisted living campus); relational/associational ("Dr. Marvin is currently with Patient Bob"). It is complicated by the presence of multiple patients, non-patient family members, and leaving the range of the home network.- Communication amid obstructions and interference: In-building operation has more multi-path interference due to walls and other obstructions, breaking down the correlation between distance and connectivity even further. Unwanted emissions and glitching are likely to be rigorously restricted and even monitored due to safety concerns, particularly around traditional life-critical medical equipment.- Multi-modal collaboration and energy conservation: Limited computational and radio communication capabilities require collaborative algorithms with energy-aware communication. Richly varied data will need to be correlated, mined, and altered. Heterogeneous devices will be on very different duty-cycles, from always-on wired-power units to tiny, stealthy, wearable units, making rendezvous for communication more difficult.- Multi-tiered data management: Data may be aggregated and mined at multiple levels, from simple on-body filtering to cross-correlation and history compression in network storage nodes. Embedded real-time databases store data of interest and allow providers to query them.2.3 Medical Practice-Driven Models and Requirements:- Records and data privacy and security: Data collected by the network is sensitive, and ownership issues are not always clear. It is likely that the healthcare provider owns the sensor and network devices, yet the data pertain to the patient. Data must be available during emergencies, but access should leave a non-repudiable “trail," so abuses can be detected. Any priority-override mechanisms must be carefully designed. One may want to f ilter out “privacy-contaminated” data, for example, a patient walks into the wrong room. The system should not “leak” this information through sensors being monitored in the room.- Role-based access control and delegation in real-time: Doctors may delegate access privileges to other doctors and nurses; family members may monitor quality-of-care for nursing home residents. The system may have DRM-like issues: “read but not copy,” “view but not save," etc. Also, patients may have read but not write privileg es for the collected sensor data, in order to avoid fraud.- Unobtrusive operation: Stealthiness is desirable, particularly for in-home and nursing home applications, where intrusive technology may not be tolerated. “Invisible” sensors are both socially more acceptable (draw less attention, more dignified) and more dangerous (unwanted tagging and surveillance).3. Roadmap: Next Generation Smart HomecareWe propose a wireless sensor network architecture for smart homecare that possesses the essential elements of each of the future medical applications, namely:- Integration with existing medical practices and technology,- Real-time, long-term, remote monitoring,- Miniature, wearable sensors, and- Assistance to the elderly and chronic patients.It extends healthcare from the traditional clinic or hospital setting to the patient's home, enabling telecare without the prohibitive costs of retrofitting existing dwellings. Currently, patients visit doctors at regular intervals, self-reporting experienced symptoms, problems, and conditions. Doctors conduct various tests to arrive at a diagnosis and then must monitor patient progress throughout treatment. In smart homecare, the WSN collects data according to a physician's specifications, removing some of the cognitive burden from the patient (who may suffer age-related memory decline) and providing a continuous record to assist diagnosis. In-home tasks are also made easier, for example, remote device control, medicine reminders, object location, and emergency communication. The architecture is multi-tiered, with both lightweight mobile components and more powerful stationary devices. Sensors are heterogeneous, and all integrate into the home network. Multiple patients and their resident family members are differentiated for sensing tasks and access privileges.Smart homecare benefits both the healthcare providers and their patients. For the providers, an automatic monitoring system is valuable for many reasons. Firstly, it frees human labor from 24/7 physical monitoring, reducing labor cost and increasing efficiency. Secondly, wearable sensor devices can sense even small changes in vital signals that humans might overlook, for example, heart rate and blood oxygen levels. Quickly notifying doctors of these changes may save human lives. Thirdly, the data collected from the wireless sensor network can be stored and integrated into a comprehensive health record of each patient, which helps physicians make more informed diagnoses. Eventually, the analyzing, diagnosis, treatment process may also be semi-automated, so a human physician can be assisted by an “electronic physician."Healthcare patients benefit from improved health as a result of faster diagnosis and treatment of diseases. Other quality-of-life issues, such as privacy, dignity, and convenience, are supported and enhanced by the ability to provide services in the patient's own home. Family members and the smart homecare network itself become part of the healthcare team. Finally, memory aids and other patient-assistance services can restore some lost independence, while preserving safety.Examples of envisioned missions where the WSNs can quickly make an impact are the following:- Sleep apnea. Every night, monitor blood oxygenation, breathing, heart rate, EEG, and EOG using on-body sensors to assess severity and pattern of obstructive sleep apnea. Home network monitors agitation (movement) and stores and reports sensor data. Network alerts provider and patient if oxygenation falls below a threshold. Monitoring can continue while treatment efficacy is assessed.- Journaling support. Journaling is a technique recommended for patients to help their physicians diagnose ailments like rheumatic diseases. Patients record changes in body functions (range of motion, pain, fatigue, sleep, headache, irritability, etc), and attempt to correlate them with environmental, behavioral, or pharmaceutical changes. The homecarenetwork can aid patients by: providing a time-synchronized channel for recording and transmitting the journal (PC, PDA, “dizziness" button); recording environmental data or external stimuli (temperature, barometric pressure, sunlight exposure, medication schedule); and quantitatively measuring changes in symptoms (pain, heart-rate, sleep disruption).- Cardiac health. Cardiac arrhythmia is any change from the normal beating of the heart. Abnormal heart rhythms can cause the heart to be less efficient, and can cause symptoms such as dizziness, fainting, or fatigue. Since they are sometimes very brief, it can be difficult to properly characterize them. Cardiac stress tests attempt to induce the event while the patient is wearing sensors in a laboratory. In a homecare setting, wearable EKG sensors can monitor for the condition continuously, over days or weeks, until the event occurs. The recorded data is promptly sent to the physician for analysis. If the event is serious enough, the emergency communication channel may be used to call for help, or it may be dispatched automatically. Other sensors in the home may be able to record environmental data to help identify the cause (side-effect of medicine, little sleep, etc.).。
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MAGAZINE工程技术计算机:人工智UNITED STATES 0001-1452AIAA J AIAA JOURNAL工程技术工程:宇航UNITED STATES 0001-1541AICHE J AICHE JOURNAL工程技术工程:化工UNITED STATES 0269-9370AIDS AIDS医学病毒学UNITED STATES 1087-2914AIDS PATIENT CARE ST A IDS PATIENT CARE AND ST医学传染病学UNITED STATES 0889-2229AIDS RES HUM RETROVAIDS RESEARCH AND HUMAN 医学病毒学UNITED STATES 1742-6405AIDS RES THER AIDS Research and Therap INFECTIOUS DISEASES ENGLAND1139-6121AIDS REV AIDS REVIEWS医学传染病学SPAIN2158-3226AIP ADV AIP Advances NANOSCIENCE & N MATERIALS SCIE UNITED STATES 1873-9318AIR QUAL ATMOS HLTHAir Quality, Atmosphere ENVIRONMENTAL SCIENCES NETHERLANDS 1748-8842AIRCR ENG AEROSP TEC A IRCRAFT ENGINEERING AND工程技术工程:宇航ENGLAND1608-5906AJAR-AFR J AIDS RESAJAR-African Journal of 医学公共卫生、环境SOUTH AFRICA 0341-051X AKTUEL RHEUMATOL AKTUELLE RHEUMATOLOGIE医学风湿病学GERMANY0001-7868AKTUEL UROL AKTUELLE UROLOGIE医学泌尿学与肾脏学GERMANY0311-5518ALCHERINGA ALCHERINGA地学古生物学ENGLAND0741-8329ALCOHOL ALCOHOL医学毒理学UNITED STATES 0735-0414ALCOHOL ALCOHOLISM ALCOHOL AND ALCOHOLISM医学药物滥用ENGLAND0145-6008ALCOHOL CLIN EXP RES A LCOHOLISM-CLINICAL AND 医学药物滥用UNITED STATES 0002-5100ALDRICHIM ACTA ALDRICHIMICA ACTA化学有机化学UNITED STATES 1980-0436ALEA-LAT AM J PROBAB L atin American Journal o STATISTICS & PROBABILITY BRAZIL2211-9264ALGAL RES Algal Research-Biomass B BIOTECHNOLOGY & APPLIED MIC NETHERLANDS 1005-3867ALGEBR COLLOQ ALGEBRA COLLOQUIUM数学数学PEOPLES R CHINA 1472-2739ALGEBR GEOM TOPOL Algebraic and Geometric 数学数学ENGLAND0002-5232ALGEBR LOG+Algebra and Logic数学数学RUSSIA1937-0652ALGEBR NUMBER THEORY A lgebra and Number Theor MATHEMATICS UNITED STATES 1386-923X ALGEBR REPRESENT THALGEBRAS AND REPRESENTAT数学数学NETHERLANDS 0002-5240ALGEBR UNIV ALGEBRA UNIVERSALIS数学数学SWITZERLAND 1748-7188ALGORITHM MOL BIOL Algorithms for Molecular生物生化研究方法ENGLAND0178-4617ALGORITHMICA ALGORITHMICA工程技术计算机:软件工UNITED STATES 0269-2813ALIMENT PHARM THER ALIMENTARY PHARMACOLOGY 医学胃肠肝病学ENGLAND0971-4693ALLELOPATHY J ALLELOPATHY JOURNAL农林科学农艺学INDIA0301-0546ALLERGOL IMMUNOPATHALLERGOLOGIA ET IMMUNOPA医学过敏SPAIN0344-5062ALLERGOLOGIE ALLERGOLOGIE医学过敏GERMANY0105-4538ALLERGY ALLERGY医学过敏ENGLAND2092-7355ALLERGY ASTHMA IMMUN T he American Academy of ALLERGY IMMUNOLOGY SOUTH KOREA 1088-5412ALLERGY ASTHMA PROCALLERGY AND ASTHMA PROCE医学过敏UNITED STATES 0002-5852ALLG FORST JAGDZTG ALLGEMEINE FORST UND JAG农林科学林学GERMANY1664-2201ALPINE BOT Alpine Botany PLANT SCIENCES SWITZERLAND 1078-6791ALTERN THER HEALTH M A lternative therapies in INTEGRATIVE & COMPLEMENTARY United States 1868-596X ALTEX-ALTERN ANIM EX A LTEX-ALTERNATIVES TO AN MEDICINE, RESEARCH & EXPERI GERMANY0893-0341ALZ DIS ASSOC DIS ALZHEIMER DISEASE & ASSO医学病理学UNITED STATES 1552-5260ALZHEIMERS DEMENT Alzheimers & Dementia医学临床神经学UNITED STATES 1758-9193ALZHEIMERS RES THERAlzheimer\'s Research an医学神经病学United Kingdom 0002-7626AM BEE J AMERICAN BEE JOURNAL生物昆虫学UNITED STATES 0002-7685AM BIOL TEACH The American Biology Tea BIOLOGY EDUCATION, SCI UNITED STATES 0002-7812AM CERAM SOC BULL AMERICAN CERAMIC SOCIETY工程技术材料科学:硅酸UNITED STATES 0002-838X AM FAM PHYSICIAN AMERICAN FAMILY PHYSICIA医学医学:内科UNITED STATES 0002-8444AM FERN J AMERICAN FERN JOURNAL生物植物科学UNITED STATES 0002-8703AM HEART J AMERICAN HEART JOURNAL医学心血管系统UNITED STATES 0002-9092AM J AGR ECON AMERICAN JOURNAL OF AGRI管理科学农业经济与政策UNITED STATES 1533-3175AM J ALZHEIMERS DISAmerican Journal of Alzh GERIATRICS & GE CLINICAL NEURO UNITED STATES 1059-0889AM J AUDIOL American Journal of Audi AUDIOLOGY & SPE OTORHINOLARYNG UNITED STATES 1526-5161AM J BIOETHICS AMERICAN JOURNAL OF BIOE社会科学科学史与科学哲UNITED STATES 0002-9122AM J BOT AMERICAN JOURNAL OF BOTA生物植物科学UNITED STATES 2156-6976AM J CANCER RES American Journal of Canc ONCOLOGY UNITED STATES 0002-9149AM J CARDIOL AMERICAN JOURNAL OF CARD医学心血管系统UNITED STATES 1175-3277AM J CARDIOVASC DRUG A merican Journal of Card医学心血管系统NEW ZEALAND 0192-415X AM J CHINESE MED AMERICAN JOURNAL OF CHIN医学全科医学与补充UNITED STATES 1175-0561AM J CLIN DERMATOL AMERICAN JOURNAL OF CLIN医学皮肤病学NEW ZEALAND 0002-9165AM J CLIN NUTR AMERICAN JOURNAL OF CLIN医学营养学UNITED STATES 0277-3732AM J CLIN ONCOL-CANC A MERICAN JOURNAL OF CLIN医学肿瘤学UNITED STATES 0002-9173AM J CLIN PATHOL AMERICAN JOURNAL OF CLIN医学病理学UNITED STATES 1062-3264AM J CRIT CARE AMERICAN JOURNAL OF CRIT医学护理UNITED STATES 0894-8275AM J DENT AMERICAN JOURNAL OF DENT医学牙科与口腔外科UNITED STATES 0193-1091AM J DERMATOPATH AMERICAN JOURNAL OF DERM医学皮肤病学UNITED STATES 0095-2990AM J DRUG ALCOHOL AB A MERICAN JOURNAL OF DRUG SUBSTANCE ABUSE UNITED STATES 0735-6757AM J EMERG MED AMERICAN JOURNAL OF EMER医学急救医学UNITED STATES 0002-9254AM J ENOL VITICULT AMERICAN JOURNAL OF ENOL农林科学生物工程与应用UNITED STATES 0002-9262AM J EPIDEMIOL AMERICAN JOURNAL OF EPID医学公共卫生、环境UNITED STATES 0195-7910AM J FOREN MED PATHAMERICAN JOURNAL OF FORE医学病理学UNITED STATES 0002-9270AM J GASTROENTEROL AMERICAN JOURNAL OF GAST医学胃肠肝病学UNITED STATES 1064-7481AM J GERIAT PSYCHIAT A MERICAN JOURNAL OF GERI医学精神病学UNITED STATES 1543-5946AM J GERIATR PHARMAC A merican Journal Geriatr GERIATRICS & GE PHARMACOLOGY &UNITED STATES 1079-2082AM J HEALTH-SYST PHAMERICAN JOURNAL OF HEAL医学药学UNITED STATES 0361-8609AM J HEMATOL AMERICAN JOURNAL OF HEMA医学血液学UNITED STATES 1049-9091AM J HOSP PALLIAT ME A merican Journal of Hosp HEALTH CARE SCIENCES & SERV UNITED STATES 1042-0533AM J HUM BIOL AMERICAN JOURNAL OF HUMA生物生物学UNITED STATES 0002-9297AM J HUM GENET AMERICAN JOURNAL OF HUMA生物遗传学UNITED STATES 0895-7061AM J HYPERTENS AMERICAN JOURNAL OF HYPE医学外周血管病UNITED STATES 0271-3586AM J IND MED AMERICAN JOURNAL OF INDU医学公共卫生、环境UNITED STATES 0196-6553AM J INFECT CONTROLAMERICAN JOURNAL OF INFE医学传染病学UNITED STATES 0272-6386AM J KIDNEY DIS AMERICAN JOURNAL OF KIDN医学泌尿学与肾脏学UNITED STATES 1088-0224AM J MANAG CARE AMERICAN JOURNAL OF MANA医学卫生保健UNITED STATES。
第一周体域网的概念、研究背景和发展领域概念及研究领域:体域网(wireless body sensor network , WBSN)又可称为生物医疗传感器网络(biomedical sensor network)和无线体域传感网(wireless body area sensor network,WBASN或BAN)。
作为无线传感器网络(wireless sensor networks,WSN)的一个分支,是人体上的生理参数收集传感器或移植到人体内的生物传感器共同形成的一个无线网络,这些传感器节点能够采集身体重要的生理信号(如温度、血糖、血压等)、人体活动或动作信号以及人体所在环境信息,处理这些信号并将它们传输到身体外部附近的本地基站。
它拥有自己的系统架构,目前多采用先分布式采集或感知、再集中式处理的方式。
由于WBSN网络规模较小,并且每对传感器节点之间的通信也不是必须的,,因此分布式采集部分经常采用星形拓扑结构。
目前的研究状况:BSN中情景感知和周围环境感知的研究;对BSN可穿戴性、可扩展性和资源优化等进行研究;基于多种通信方式构建混合的BSN,移动BSN中跟踪和能量感知MAC;从低能耗和通信的角度构建新型的BSN系统对BSN的架构展开了深入研究;构建新型的BSN平台并对BSN中数据融合技术;BSN对人体活动的监控;此外BSN的自适应性和可调节性、中间件、信号处理算法、健康及活动监控和网络可靠性研究领域:信道研究;无线体域网帧结构设计;基于体域网路由设计;基于蓝牙的体域网研究;关键技术:WBAN是一种新的交叉技术,和无线个域网(WPAN)、无限传感网络(WSN)、泛在传感网络(USN)、无限短距通信技术、传感器技术等都有密切关系。
WBAN的关键问题是要实现终端到终端间的通信,主要使用短距无线通信,如UWB,ZigBee和NFC等。
实现WBAN需要的短距信息技术主要考虑再相同的功率下数据传输速率更高,或者在相同的数据传输速率下需要的功率更低。
1.生物体信号检测传感器 - Biosignal Detection Sensors2.生物医学成像传感器 - Biomedical Imaging Sensors3.体内植入式传感器 - Implantable Sensors4.生物标记物检测传感器 - Biosensing for Biomarker Detection5.生物医学传感器的纳米技术应用 - Nanotechnology Applications in BiomedicalSensors6.远程医疗监测传感器 - Remote Healthcare Monitoring Sensors7.生物医学传感器中的智能材料 - Smart Materials in Biomedical Sensors8.生物医学传感器网络 - Biomedical Sensor Networks9.生物医学传感器中的微流控技术 - Microfluidics in Biomedical Sensors10.生物医学传感器中的脑机接口 - Brain-Machine Interfaces in Biomedical Sensors11.生物医学传感器的生物信息学分析- Bioinformatics Analysis in BiomedicalSensors12.生物医学传感器中的生物反馈技术 - Biofeedback Technologies in BiomedicalSensors13.生物医学传感器中的光学成像技术- Optical Imaging Technologies inBiomedical Sensors14.生物医学传感器中的电生理监测- Electrophysiological Monitoring inBiomedical Sensors15.生物医学传感器中的荧光探针技术- Fluorescent Probe Technologies inBiomedical Sensors16.基因传感器- Genomic Sensors17.生物医学传感器中的人工智能应用- Artificial Intelligence Applications inBiomedical Sensors18.生物医学传感器中的免疫传感技术 - Immunoassay Technologies in BiomedicalSensors19.生物医学传感器中的生物成像技术 - Bioluminescence Imaging Technologies inBiomedical Sensors20.生物医学传感器中的磁共振成像 - Magnetic Resonance Imaging in BiomedicalSensors21.生物医学传感器中的超声波成像 - Ultrasound Imaging in Biomedical Sensors22.生物医学传感器中的分子诊断技术- Molecular Diagnostic Technologies inBiomedical Sensors23.生物医学传感器中的微电极阵列 - Microelectrode Arrays in Biomedical Sensors24.生物医学传感器中的多模态成像 - Multimodal Imaging in Biomedical Sensors25.生物医学传感器中的医学纳米技术- Medical Nanotechnology in BiomedicalSensors26.生物医学传感器中的生物电信号分析- Biopotential Signal Analysis inBiomedical Sensors27.生物医学传感器中的光声成像技术- Photoacoustic Imaging in BiomedicalSensors28.生物医学传感器中的神经激励技术- Neurostimulation Technologies inBiomedical Sensors29.生物医学传感器中的细胞成像技术- Cellular Imaging Technologies inBiomedical Sensors30.生物医学传感器中的蛋白质传感 - Protein Sensing in Biomedical Sensors。
无线传感器网络论文英文版Wireless Sensor Networks: A Research PaperAbstract:Wireless Sensor Networks (WSNs) have emerged as a revolutionary technology in the field of wireless communication. This research paper aims to provide an overview of WSNs, their applications, challenges, and future prospects.1. Introduction:Wireless Sensor Networks are interconnected nodes that can communicate with each other through wireless protocols. These nodes, equipped with sensors, provide real-time data from physical environments. WSNs have gained significant attention due to their applicability in various industries such as healthcare, agriculture, environmental monitoring, and surveillance.2. Architecture of Wireless Sensor Networks:The architecture of WSNs consists of three main components: sensor nodes, sinks or base stations, and a network infrastructure. Sensor nodes gather information from the environment and transmit it to the sink or base station via multi-hopping or direct transmission. The network infrastructure manages the routing and data aggregation processes.3. Applications of Wireless Sensor Networks:3.1 Environmental Monitoring:WSNs play a crucial role in monitoring environmental parameters such as temperature, humidity, air quality, and water quality. This data is essential for environmental research, disaster management, and habitat monitoring.3.2 Healthcare:WSNs have revolutionized the healthcare industry by enabling remote patient monitoring, fall detection, and medication adherence. These networks assist in providing personalized and timely healthcare services.3.3 Agriculture:In the agricultural sector, WSNs are deployed for crop monitoring, irrigation management, and pest control. The data collected by these networks help farmers enhance crop productivity and reduce resource wastage.3.4 Surveillance:WSNs are extensively employed in surveillance systems to monitor public areas, monitor traffic congestion, and ensure public safety. These networks provide real-time data for efficient decision-making and threat detection.4. Challenges in Wireless Sensor Networks:4.1 Energy Efficiency:Sensor nodes in WSNs are usually battery-powered, making energy efficiency a critical challenge. Researchers are focused on developing energy-efficient protocols and algorithms to prolong the network's lifespan.4.2 Security and Privacy:As WSNs collect sensitive data, ensuring the security and privacy of transmitted information is crucial. Encryption techniques, intrusion detection systems, and secure routing protocols are being developed to address these concerns.4.3 Scalability:Scalability is a critical challenge in large-scale deployment of WSNs. Designing scalable architectures and protocols enable efficient communication and management of a large number of sensor nodes.5. Future Prospects of Wireless Sensor Networks:The future of WSNs is promising, with advancements in technologies such as Internet of Things (IoT) and Artificial Intelligence (AI). Integration of WSNs with IoT devices will enable seamless communication and data exchange. AI algorithms can facilitate intelligent data analysis and decision-making.Conclusion:Wireless Sensor Networks have shown tremendous potential in various fields and continue to evolve with advancements in technology. Addressing energy efficiency, security, and scalability challenges will contribute to the widespread adoption of WSNs. As researchers continue to explore new possibilities, WSNs will become an integral part of our daily lives, transforming industries and enhancing our quality of life.。
Abstract—This paper presents a system based on Ambient Intelligence (AmI) to foster home care monitoring of senior citizens and chronically ill patients. The most important fact addressed in this research is the development of non intrusive and easy to use sensing devices. According to this, medical tests do not need user collaboration to perform them, neither powering on and off the sensor, starting the measure, configuring communications, etc.I.I NTRODUCTIONORLD population is aging and new technologydevelopments need to be faced in order to support and to improve healthcare delivery, especially to those chronically ill and old. Research experiences in the past, cryout for the improvement in human-machine interfaces that enable users (i.e. mostly old people) to deal easily and non-intrusively with technology [1]-[3]. Lately, innovation in the area has come with Ambient Intelligence (AmI) [4],[5] as limitations brought on by aging are expected to be overcome by new technologies, based on the design of easy to use and to learn devices that work transparently and pervasively to aid the user [6].Therefore, next generation follow-up and homecare systems have several important challenges to face. On the one hand, from the users’ side, there is a need to develop non-intrusive systems that require a minimum human-machine interaction and provide the right medical services on a highly-usable basis, enhancing the augmented environment while making computers disappear in the background. On the other hand, the big issue is to implement these necessities by means of affordable solutions for public and private healthcare institutions, only achievable by means of low cost structures easy to install and to maintain.Silvia Jiménez-Fernández, Antonio Cobo-Sánchez de Rojas, Francisco del Pozo-Guerrero and Paula de Toledo-Heras are with the Bioengineering and Telemedicine Research Centre of the Technical University of Madrid – Spain ({sjimenez, acobo, fpozo, paula}@gbt.tfo.upm.es).Silvia Jiménez-Fernández is now Associate Professor in University of Alcalá – Spain, while Paula de Toledo-Heras is now Visiting Professor in Carlos III University of Madrid – Spain.Álvaro Araujo-Pinto, Octavio Nieto-Taladriz, and José Manuel Moya-Fernández are with the Integrated Circuits Laboratory, Technical University of Madrid – Spain ({araujo, nieto, josem}@die.upm.es)II.M ETHODOLOGYIn order to achieve these requirements, a system based on Ambient Intelligence has been designed and implemented. It features a gateway, several biomedical sensors that the doctor recommends to the patient to control his/her health (pulse oximeter, electrocardiograph and accelerometer to quantify daily activity) and a user interface, essential to give commands to the user (such as start of the exam, low battery supply, etc). All network nodes are provided of wireless capabilities to allow full mobility within the Personal Area Network (PAN) [7]. The abovementioned architecture can be found in figure 1.Figure 1. System architectureA.RequirementsThe requirements taken into account when designing the wireless sensor network, or personal area network, make it different to other networks, such as Internet. These are stated below:-Self-management.The wireless network has to, automatically, route data packets using neighbor nodesas well as to adapt its topology to network changes.That is to say that the user does not have to take care ofadding new nodes/sensors to the network or considernodes’ breakup.-Context awareness. In AmI scenarios, the networks should adapt their behavior accordingly to environmental variables that govern the system: such asthe actor of the system and his/her preferences, momentof the day when usage takes place, season, etc.PERSEIA: a Biomedical Wireless Sensor Network to Support Healthcare Delivery for the Elderly and Chronically IllSilvia Jiménez-Fernández, Álvaro Araujo-Pinto, Antonio Cobo-Sánchez de Rojas, Francisco del Pozo-Guerrero Senior Member IEEE, Octavio Nieto-Taladriz, Paula de Toledo-Herasand José Manuel Moya-FernándezWThEP13.6 1-4244-0033-3/06/$20.00 ©2006 IEEE.2064-Heterogeneity and dynamism. Devices of different characteristics and nature must be interoperable and able to adapt to a network that can have different nodesdepending on the environment, the user, and the application.-Low cost. Perfectly designed networks cannot be deployed massively if they are costly. Moreover, healthcare providers will not use them in clinical routineif they are not cost-efficient or do not have important benefits over traditional healthcare delivery.-Limited resources. Limited processing power, tight memory sizes, or low power consumption are crucial for this design. Batteries are required to last long enough to allow several measures to take place, as well as to support the wireless radio link power consumption.-Security. Refusing intrusions, avoiding denial of service, driving the system into a safe state in case of failure, etc. are a must for real scenario setups, as sensitive and personal data will be in transit through thenetwork.B.FunctionalityApart from the requirements stated above, essential functionality of the different elements follows. The gateway has twofold capability: 1) it is used to communicate with the sensors that the patient has, and 2) it is needed to send data to and from the healthcare institutions (i.e. hospital, primary care, etc.). The information regarding the doctor’s prescription of medical exams is sent to the gateway, where it is stored, processed and routed to the specific sensor, stating the duration, sample rate, quality of the measure, amplification factor, or any precise parameter needed to collect the data.The sensors have been developed as stand alone wireless devices and have been provided of automatic start of the measure, auto-discovery, and auto-configuration facilities. That is to say that the patient does not need to take care of configuring nor connecting them, for instance, to upload or download the data collected. It is important to note that the user does not need to ensure either that the sensors are powered on and off, as they are suspended and resume automatically after a given time. When resume is done, every half minute, several tasks take place:1)Checking the state of the sensor to become aware of thepatient’s willingness to start an exam. When the user wants to commence it, he/she places the sensor on, so that the device is able to collect data. This situation takes place no matter if the doctor programmed the test or if the patient decided to take it by himself/herself (because not feeling alright).2)Connecting to the gateway. The radiofrequency moduleis powered on and a “keep alive” message is sent to thegateway. If there is information that needs to be transmitted to the device, as imminent exams that needto take place, it is sent at this moment. Afterwards, ifdata are still stored in the sensor, they are forwarded tothe gateway.3)Checking battery level. When batteries are close to beused up, an alarm is sent to the gateway and the user isnotified so that he/she can recharge them. This check isperformed every ten minutes instead of every half minute.Once all these tasks have been performed, the device is suspended again to save batteries. Using this method, battery consumption is decreased up to a maximum of 60 percent.III.R ESULTSThe abovementioned approach has led to the definition and development of a system employing the concepts of Ambient Intelligence to foster independent living of the elderly.This has been achieved using a gateway to route information from the house to the outside world (hospitals, private institutions, etc.), and also within the home environment, through a network of monitoring sensors. In order to minimize maintenance and installation costs, as well as to improve usability, a wireless network (LR-WPAN) has been used to interconnect the sensors and the hub.Each node (i.e. sensing device) has three different parts. First, the biomedical sensor itself: an off-the-shelf OEM board (ECG, pulse oximeter) or an ad-hoc module (accelerometer) that has been provided of a second component, an autonomous power supply. As the power requirements of each sensor are different, customized supply stages have been designed using a standard interface with commercial AAA batteries, and always looking for the highest efficiency that maximizes sensors’ life time. Finally, the third part that has been added provides the “intelligence” explained in the requirements section: awareness of patient’s willingness to perform a measurement, network functionality (e.g. routing, reconfiguration), etc. The main component of this stage is a radio transceiver in the ISM band of 2,4 GHz that implements the physical layer and the MAC layer of the IEEE 802.15.4 wireless standard. The main characteristics featured are:-Possible bit rates: 250 Kbps, 40 Kbps or 20 Kbps. We are using 250Kbps.-Possible network topologies: star or point to point. We are using star topology.-Support for low latency devices.-Channel access using CSMA-CD (Carrier Sense Multiple Access/Collision Detection).-Dynamic address allocation.-Low power consumption.Therefore, our network requirements and functionality suit perfectly with the given standard. In order to implement2065the remaining layers of the protocol stack a low-cost PIC 16F microcontroller that connects to the radio transceiver through a SPI communication interface has been used. The commonly used OSI architecture has been refused in favor of an architecture based on services. The goal pursued with this design is the implementation of applications that arise as a mere aggregation of services and relations between services, rather than a node-focused orientation, simplifying the development of user applications [8]. Our services are built on top of a communication middleware [9], [10] that abstracts network or hardware specific tasks to the application. This middleware allows sending data to any node of the network without considering its location, sending broadcast messages, etc, and all this happens using a simple and unique interface (based on query-response) that can be dynamically instantiated in any node at any time. This allows to easily compose applications taking into account many complex aspects, such as privacy, safety, load balancing, low energy consumption, etc [11], [12], and in a totally transparent way to the user. The protocol stack can bedepicted in figure 2.Figure 2. Protocol stackThe idea behind all this approach is to isolate common behavior that can be reused from other applications and to encapsulate it as system services, so that once the system is running the addition of a new applications becomes easy. Another important fact that has to be emphasized is that, in contrast to traditional architectures, service oriented architectures do not force all services to access all middleware/layers available (as can be seen in figure 2). For instance, in order to check battery levels, communication protocols can be bypassed and access to physical level directly used, making signal processing more efficient.All in all, an interoperable, reliable system, abstracting the hardware from the applications has been designed, developed and implemented. It is important to highlight that the size of the prototype is not comparable to that of wearable devices, but the aim of this work was just to emulate the behavior that wearable sensors will have in the future, not to miniaturize existing ones.IV.C ONCLUSIONSDeepening in the usability concept, this project has aimed to develop an intelligent and intuitive interface, embedded in everyday objects, able to respond to the activities and situations recognized in the user’s environment.The primary objective of this platform is to examine whether a system of basic biomedical sensors (motion sensors, ecg, pulse oximetry, blood pressure, etc.) is able to detect behavioral patterns and help aging and ill populations with everyday activities and health care follow up. That is to say, to provide the foundation for an Ambient Intelligence approach.Finally, a flexible, dynamic and easy to program architecture has been implemented, enabling software developers to focus on application level without paying attention to network and hardware levels.A CKNOWLEDGMENTThe authors would like to thank Pedro Malagón for his support during the development of the system.R EFERENCES[1]Ades PA, Pashkow FJ, Fletcher G, Pina IL, Zohman LR, Nestor JR. Acontrolled trial of cardiac rehabilitation in the home setting using electrocardiographic and voice transtelephonic monitoring. Am Heart J. vol 139, sup 3, pp 543-8. 2000.[2]Morlion B, Knoop C, Paiva M, Estenne M. Internet-based homemonitoring of pulmonary function after lung transplantation.American Journal of Respiratory and Critical Care Medicine vol 165, sup 5, pp 694-697. 2002.[3]Hernandez C, Casas A, Escarrabill et al. Home hospitalization ofexacerbated COPD patients. 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