•论著•麻醉深度指数和Narcotrend指数的临床应用比较李姣阳杨玉峰宫春利曾毅空军军医大学附属西京医院麻醉科，西安710032通信作者：曾毅，Email:zengyil014@163.co m【摘要】目的探讨麻醉深度指数(depth of anesthesia im丨ex, A I)在全凭静脉麻醉中的应用，并与Narcotrend指数（Narcotrend Index, NI) 进行比较。
方法择期全身麻醉下行支撑喉显微镜手术的患者40例，年龄丨8~65岁，A S A分级I ,11级，同时监测患者A I、N I及丙泊酚效应室浓度（effect-site concentralirni, C e)。
麻醉诱导气管插管后，持续泵注丙泊酚、瑞芬太尼、米库氯 铵维持麻醉。
记录数据信号稳定后(T,)、诱导前(T2)、插管前(T3)、插管后1min(T4)、插管后3 m in(T5)、插管后5 min(T6)、置喉 镜前(T7)、置喉镜后1m in(T8)、置喉镜后5 min(T9)、手术结束(T,。
）、苏醒(T,,)、拔管(T,2)12个时点的A I、N I、Ce。
结果随着麻醉深度的变化，A I和N I的变化趋势一致。
A丨与N I、Ce•的相关系数分别为0.913(f><0.05)、-0.599(P<0.05) , N1和Ce的相关系数为-0.584(户<0.05),人1、!\1尤6三者具有良好的相关性=结论A I和N1均能准确反映患者手术不同阶段的麻醉 深度，A I监测用于全凭静脉麻醉可较好地控制麻醉深度，指导合理用药,避免患者术中知晓。
【关键词】麻醉深度指数；Narcotrend指数；麻醉深度D0I ： 10.3760/cma. j,cn321761 -20191201 -00168Comparison of clinical application of depth of anesthesia index and Narcotrend IndexLi Jiaoyang, Yang Yufeng, Gong Chunli, Zeng YiDepartment o f A nesthesiology, Xijing Hospital, Air Force Medical University, Xi'an 7 J0032, ChinaCorresponding author: Zeng Yi, Email:******************【Abstract】Objective To explore the application of depth of anesthesia index (A I) during total intravenous an esth esia, and com pare it with Narcotrend Index (NI). Methods C hoosing 40ca ses of patients who underwent laryngeal surgery under general a nesth esia, aged 18-65, A m erican Society of Andrology (ASA) I to I I. The AI, NI and propofol effect-site concentrations (Ce) o f patients were monitored sim ultaneously. After intubation, propofol, rem ifentanil and mivacurium were continuously infused to maintain a d equate depth of an esth esia. The AI, NI, and Ce were recorded at the time points of stable sign als began to show up (T,), before the in d uction (T2), before intubation (TJ, 1min after intubation (T4), 3 min after intubation (T5), 5 min after intubation (T6), before p lacing the la-ryngoscopy(T7), 1min after placing the laryngoscopy (T8), 5 min after placing the laryngoscopy (T9) end of the surgery (Tl0), arousal (Tn) and extubation (T12). Results A s the depth of anesthesia changes, the trends of AI and NI are consistent. The correlation coefficients of AI, NI and Ce are 0.913, -0.599, the correlation coefficients of NI and Ce is -0.584. The changing ten dencies of AI X NI and Ce correlated w ell to each other. Conclusions Both AI and NI can reflect the depth of anesthesia of patients at different stages of the operation accurately. The application of AI monitoring during intravenous an esth esia can better control the depth of a n esth esia, guide the rational u se of m edication, and avoid the patient's intraoperative aw areness.【Key words】Depth of an esth esia index; Narcotrend Index; Depth of anesthesiaDOI ：10.3760/r m 321761-20191201 -00168全身麻醉适用于各类手术。
