BX53 显微镜参数

三目显微镜技术参数
1.1、光学系统：无限远校正光学系统，齐焦距离必须为国际标准45mm,光学系统视场数最大支持≥26
1.2、调焦机构：最小微调刻度单位≤1微米，载物台垂直运动方式距离≥25mm，带聚焦粗调上限停止位置，粗调旋钮扭矩可调，微调旋钮可以安装在显微镜的左右手任意一边。

1.3、观察镜筒：高级三目观察筒分光比可调节档位≥三档，分光比为双目/摄像：100%/0、20%/80%、0/100%
1.4、照明装置：≥12V100W卤素灯，光强预调开关。

内置式滤色镜（日光平衡滤色片、ND25、ND6），左右手均可操作。

1.5、研究级物镜：万能平场消色差物镜4×(N.A.≥0.1) 、10×(N.A.≥0.25)、20×(N.A.≥0.4)、40×(N.A.≥0.65)物镜的外壳上标有“N”字样物镜
1.6、载物台：右手低位置同轴驱动选钮的高抗磨损性陶瓷覆盖层载物台。

1.7、目镜：10X宽视野目镜
1.8 、物镜转换器：≥六孔物镜转换器,带有检偏器插槽的
1.9 、聚光镜：摇摆式聚光镜，N.A.≥0.8，用于1.25～100×
1.10、优越拓展性能：①≥8孔荧光照明装置，左右手都能控制的荧光照明光闸，无需更换滤色镜组，能够同时对多种染色的标本进行成像②十人共览装置③暗场聚光镜④相差装置⑤测微尺等
1.11、节能环保开关装置：具备节能感应开关，操作人员离开30分钟后自动关闭透射光源。

节能开关既节约能源又保护了光源的使用寿命。

配置清单
2.1 显微镜主机BX53 1套
2.2 物镜4X、10X 、20X 、40X 1套
2.3 目镜10X 2个。

BX3 Microscope Unit Guide BX63/BX53/BX43/BX46BX3 SeriesSystem MicroscopePLN (PLN-PH) SeriesAppropriate for a range of biological applications, these high-quality objectives offer flatness up to OFN 22 in transmitted brightfield (phase contrast) observation. The PLN-PH series is designed for phase contrast observation.PLAPON SeriesDesigned for high resolution andcontrast, Plan Apochromat objectivesreduce chromatic aberration to lowlevels.UPLFLN (UPLFLN-PH) SeriesThese Plan objectives provide flat imageswith high transmission up to the near-infrared region of the spectrum. Withtheir high signal-to-noise ratio, highresolution, and high contrast images,the objectives are especially effective inbrightfield and Nomarski DIC observations.The UPLFLN-PH series is optimized forphase contrast observation.1Objective Lens NA W.D.(mm)OFNCover GlassThickness(mm)Immersion SpringLoadedPLN2X0.06 5.822-PLN4X0.1018.522-PLN10X0.2510.622-PLN20X0.40 1.2220.17✓PLN40X0.650.6220.17✓PLN50XOI0.9-0.50.222-Oil✓PLN100XO 1.250.1522-Oil✓LPLN40X0.60 3.4-4.1220-1PLN10XPH0.2510.622-PLN20XPH0.40 1.2220.17✓PLN40XPH0.650.6220.17✓PLN100XOPH 1.250.1522-Oil✓UPLFLN4X0.131726.5-UPLFLN10X20.301026.5-UPLFLN20X0.50 2.126.50.17UPLFLN40X0.750.5126.50.17✓Objective Lens NA W.D.(mm)OFNCover GlassThickness(mm)Immersion SpringLoadedUPLFLN100XO2 1.300.226.50.17Oil✓UPLFLN100XOI2 1.3-0.60.226.50.17Oil✓UPLFLN10X2PH0.301026.5-UPLFLN20XPH0.50 2.126.50.17UPLFLN40XPH0.750.5126.50.17✓UPLFLN100XO2PH 1.300.226.50.17Oil✓PLAPON1.25X0.04 5.026.5-PLAPON2X0.08 6.226.5-MPLFLN10X0.301126.5-MPLFLN20X0.45 3.126.50MPLFLN40X0.750.6326.50✓MPLFLN100X0.90126.50MPLAPON60X0.900.426.50✓MPLAPON100X0.950.3526.50✓MPLAPON100XO2 1.450.1026.50Oil✓UPLXAPO SeriesThanks to novel manufacturing technology, Olympus UPLXAPO high-performance objectives offer improved optical performance in three critical areas—a larger numerical aperture (NA), better image flatness, and a wider range of chromatic correction. These advances enable high-quality, large field of view (FOV) imaging for versatility in numerous applications.Olympus’ BX3 series can be configured to meet the needs of your research. The combination of leading-edge imaging capabilities with the flexibility to customize the system to your specific application makes BX3 series microscopes powerful research tools.Series Objective Lens NA W.D.(mm)OFNCover GlassThickness(mm)ChromaticCorrectionRangeSpringLoadedX Line U LXA O4X0.161326.5-400-1000 nmU LXA O10X0.40 3.126.50.17400-1000 nmU LXA O20X0.800.626.50.17400-1000 nm✓U LXA O40X0.950.1826.50.11-0.23400-1000 nm✓U LXA O40XO 1.400.1326.50.17400-1000 nm✓U LXA O60XO 1.420.1526.50.17400-1000 nm✓U LXA O100XO 1.450.1326.50.17400-1000 nm✓U LXA O60XO H 1.420.1526.50.17400-1000 nm✓UPLXAPO100XOPH 1.450.1326.50.17400-1000 nm✓Objective LensIntroductionAccessories2Main Type Brightness BX43FManual2W LED Light Source (30W Halogen Equivalent)BX46F Manual2W LED Light Source (30W Halogen Equivalent)BX53F2Manual / Motorized14W LED Light Source (100W Halogen Equivalent)BX63F Motorized2W LED Light Source or 12V 100W Halogen Light SourceMicroscope FramesObservation Tube FN Type Angle Type FeatureU-BI30-222Binocular Fixing -U-TBI-322Binocular Tilting High Eye Point U-TBI-3-CLI 22Binocular Tilting Low Eye Point U-TTBI 22Binocular Tilting Telescopic U-TTLBI 22Binocular Tilting Lift Adjustment, TelescopicU-ETR-422Trinocular Fixing Erected ImageU-TR30-222Trinocular Fixing -U-TTR-222Trinocular Tilting -U-SWTR-326.5Trinocular Fixing Super Widefield U-SWETTR-526.5TrinocularTiltingErected Image, Super WidefieldObservation TubesEyepieces FN Reticle HelicoidWHN10X 22-WHN10X-H 22-✓CROSSWHN10X 22Crosshair✓SWH10X-H26.5-✓EyepiecesBX53F2U-TTR-2SWH10X-H WHN10X WHN10X-H CROSSWHN10X3Intermediate Tube Description U-EPA2Eyepoint Adjuster U-EPAL-2Eyepoint Adjuster U-CA Magnification ChangerU-KPA Intermediate Attachment for Simple Polarizing ObservationU-TRU Trinocular Intermediate Unit U-TRUS Trinocular Intermediate UnitU-DP Dual Port U-DP1XCDual Port 1XIntermediate TubesBright Field Light Source Bulb Brightness U-LH100-3Halogen 12V100WU-LHLEDC LED 2W (30W Halogen Equivalent)U-LHLEDC100LED14W (100W Halogen Equivalent)Bright Field Light SourcesIllumination Tube # of FL CubeTurret Type Illumination PatternBX3-URA 8Manual Normal BX3-RFAS 8Coded FlyEye BX3-RFAA8MotorizedFlyEyeIllumination TubesBX3-RFAAFluorescence Light Source Description U-HGLGPS Light SourceU-LH100HG 100 W Mercury Lamp Housing U-LH100HGAPO100 W Mercury Apo Lamp HousingFluorescence Light SourcesU-HGLGPSU-TRUMotorized Controller Description U-HSCBM Hand Switch for CBM U-HSEXP Hand Switch for ExposureBX3M-HSRE Hand Switch U-MCZ Controller BX3-CBH Control Box BX3-CBM Control BoxU-CBS Control Box for Coded Function U-IFRESInterface for Coded NosepieceMotorized ControllerU-MCZ4Nosepieces Type # of ObjectivesWorking SlotU-5RE-2Manual 5BX43-5RES Coded 5U-D6RE Manual 6✓U-D6RES Coded 6✓U-D7RES Coded 7✓U-D7REAMotorized7✓NosepiecesSample Holder Handle # of Slide Thickness U-HLD-4Left Double Thin U-HLDT-4Left Double Thick U-HLS-4Left Single Thin U-HLST-4Left Single Thick U-HRD-4Right Double ThinU-HRDT-4RightDoubleThickSample HoldersStage Accessories DescriptionBX3-SHEA Stage Handle Extention AdaptorU-SHG Rubber Grip U-SHGTRubber Grip (Thick)Stage AccessoriesStage Control HandleType Applicable SystemU-SVLB-4Left Manual All U-SVRB-4Right Manual All U-SVRC Right Manual Only BX46U-SVRC-CY Right Manual Only BX46BX3-SSU Motorized Motorized Only BX63U-SP No Handle Manual All IX-SVL2LeftManualOnly BX63StagesU-D7REAU-HR(L)DT -45TV Adaptor Description U-TV0.35XC-20.35X C-Mount Adaptor U-TV0.5XC-30.5X C-Mount Adaptor U-TV0.63XC 0.5X C-Mount Adaptor U-TV1XC 1X C-Mount Adaptor (XY adjustment)U-TV1X-2TV Adaptor U-CMAD3C-Mount Adaptor U-BMAD Bayonet-Mount Adaptor U-SMAD Sony Mount Adaptor U-TMAD T-Mount Adaptor U-FMT F-Mount Adaptor U-CMT C-Mount Adaptor U-DPCADDouble Port Tubes with C MountsTV AdaptorsCondenser NA Type Contrast MethodU-AC2 1.1Manual BF U-SC30.9Manual BF/PO U-LC 0.75Manual BF/PO U-AAC 1.4Manual BF U-PCD2 1.1Manual BF/PH/DF U-DCD 0.92Manual DF U-DCW 1.4Manual DF U-UCD8-2Oil Top Lens 1.4 / Dry Top Lens 0.9Manual BF/PH/DIC/DF/PO BX3-UCD8AOil Top Lens 1.4 / Dry Top Lens 0.9MotorizedBF/PH/DIC/DF/POCondensersAccessoriesU-TV0.63XCU-TV0.35XC-2BX3-UCD8AU-PCD2U-DCWU-DCDU-SC3U-AC2U-LCU-AACU-UCD8-2U-TV0.5XC-3U-TV1XCU-TV1X-2+U-CMAD3U-TV1X-2+U-BMAD6Polarizer/Analyzer/DIC Slider Description U-POT Polarizer BX45-PO PolarizerU-ANT Analyzer for Transmitted LightU-AN-2Analyzer SliderU-GAN Analyzer for Urate Crystals ObservationU-DFA Darkfield Ring U-PH1-S Phase Contrast Ring (small)U-PH2-S Phase Contrast Ring (small)U-PH3-S Phase Contrast Ring (small)U-DIC10DIC Prism U-DIC10S DIC Prism (small)U-DIC20DIC Prism U-DIC40DIC Prism U-DIC60DIC Prism U-DIC100DIC PrismU-DICT DIC Slider for Transmitted Light U-DICTS Shift DIC Slider for Transmitted LightU-FDICTDIC Mirror UnitPolarizer/Analyzer/DIC SliderMirror Unit Excitation FilterEmission FilterDichroic MirrorU-FF No Filter No Filter No Mirror U-FUW BP340-390BA420IF DM410U-FUN BP360-370BA420IF DM410U-FUNA BP360-370BA420-460DM410U-FBVW BP400-440BA460IF DM455U-FBW BP460-495BA510IF DM505U-FBWA BP460-495BA510-550DM505U-FBN BP470-495BA510IF DM505U-FBNA BP470-495BA510-550DM505U-FGW BP530-550BA575IF DM570U-FGWA BP530-550BA575-625DM570U-FGNA BP540-550BA575-625DM570U-FYW BP540-585BA600IF DM595U-FCFP BP425-445CFP BA460-510CFP DM455CFP U-FGFP BP460-480GFP BA495-540GFP DM490GFP U-FYFP BP490-500YFP BA515-560YFP DM515YFP U-FRFP BP535-555HQ BA570-625HQ DM565HQ U-FMCHEBP565-585BA600-690DM595Mirror UnitsU-DICTGroup Observation SystemsMulti-head discussion systems are invaluable for lab training and education. Olympus offers discussion systems for as few as two or as many as 26 people. With our BX3 series multi-discussion observation (MDO) system, every participant can see the same high-quality image. The integrated LED arrow pointer helps instructors highlight key features in the teaching specimen.Front to Back ObservationSide-by-Side ObservationHeads 22359101826Shape Front to BackSide by SideLinearLinearLinearH-ShapeH-ShapeH-ShapeU-DO31U-SDO31U-MDOB3111U-MDO10B3111U-MDO10R31U-MDOSV 1244812BX3-MDO18R 11BX3-MDOE248Multi Observation for 9 peopleMulti Observation for 26 people7BX46 System DiagramBX46 SYSTEM DIAGRAM Array8BX63 SYSTEM DIAGRAM910System DiagramBX53 System DiagramBX53 SYSTEM DIAGRAM Array1112System DiagramBX43 System DiagramBX43 SYSTEM DIAGRAM Array1314Microscope Frame Optical System UIS2 optical systemFocusBuilt-in motorized nosepiece focusStroke: 20 mm; minimum increment: 0.01 µm; maximum nosepiece movement speed: 5 mm/s IlluminatorBuilt-in Köhler illumination for transmitted light, light intensity LED indicator, built-in motorized field stop• High color reproductivity LED light source•12 V 100 W halogen bulb (pre-centered)Revolving Nosepiece • Motorized septuple revolving nosepiece• Interchangeable reversed coded sextuple/coded septuple nosepieceObservation Tube Widefield (FN 22)• Widefield tilting trinocular• Widefield trinocular• Widefield erect image trinocular• Widefield tilting binocular• Widefield tilting, telescopic, lifting binocular • Widefield ergo binocular• Widefield binocularStage • Ultrasonic stage (Stage stroke: X: 76 mm × Y: 52 mm; maximum stage movement speed: 30 mm/s • Ceramic-coated coaxial stage with left or right hand low drive control: with rotating mechanism and torque adjustment mechanism, optional rubber grips, and available stage handle extension adaptor• Cross stage with short left handleCondenser • Motorized universal condenser (NA 0.9, motorized 8-position turret, aperture stop, polarizing filter in/outmechanism, and top lens swing out mechanism), for 1.25X–100X [swing-out 1.25X-4X, with oil top lens: (NA 1.4)] • Swing out Achromatic (NA 0.9), for 1.25X–100X (swing-out: 1.25X–4X)• Achromatic Aplanatic (NA 1.4), for 10X–100X• Universal (NA 0.9), for 1.25X–100X [swing-out: 1.25X–4X, with oil top lens: (NA 1.4)]• Darkfield dry (NA 0.8–0.92), for 10X–100X• Darkfield oil (NA 1.20–1.40), for 20X–100XND Filter Wheel• Motorized 6-position ND filter wheelFluorescence Illuminator • Motorized multi-purpose coded type (FN 22, motorized 8-position mirror unit turret, 4-position ND slider) • Multi-purpose coded type (FN 22, 8-position mirror unit turret, 4-position ND slider)Fluorescence Light Source • 130 W mercury light guide illumination• 100 W mercury apo lamp housing and power supply unit • 100 W mercury lamp housing and power supply unitController• High-performance control box ( I/F: FireWire) BX63 SPECIFICATIONSMicroscope Frame Optical System UIS2 optical systemFocusVertical stage movement: 25 mm stage stroke with coarse adjustment limit stopper, torque adjustment for coarseadjustment knobs, stage mounting position variable, high sensitivity fine focusing knob (minimum adjustmentgradations: 1 μm)IlluminatorBuilt-in Koehler illumination for transmitted light, light preset switch, light intensity manager switch, high colorreproductivity 14 W LED light source (Brightness: equivalent to or brighter than a 100W halogen lamp,LED light emission method: 405nm excited RGB fluorescence substance)Revolving Nosepiece Interchangeable reversed quintuple/sextuple/septuple/coded sextuple/coded septuple nosepieceObservation Tube Widefield (FN 22)• Widefield tilting trinocular• Widefield trinocular• Widefield tilting binocular• Widefield tilting, telescoping and lifting binocular• Widefield ergo binocular• Widefield binocularSuper Widefield (FN 26.5)• Super widefield trinocular• Super widefield erect image tilting trinocularStage C eramic-coated coaxial stage with left or right hand low drive control: with rotating mechanism and torque adjustment mechanism, optional rubber grips and stage handle extension adaptor available (non stick grooved coaxial, plain, rotatable stages are also available)Condenser • Abbe (NA 1.1), for 4X–100X• Swing out Achromatic (NA 0.9), for 1.25X–100X (swing-out: 1.25X–4X)• Achromatic Aplanatic (NA 1.4), for 10X–100X• Phase contrast, darkfield (NA 1.1), [phase contrast: for 10X–100X, darkfield: for 10X–100X (up to NA 0.80)]• Universal (NA 0.9), for 1.25X–100X [swing-out: 1.25X–4X, with oil top lens:(NA 1.4)]• Low (NA 0.75), for 2X–100X (Dry)• Darkfield dry (NA 0.8–0.92), for 10X–100X• Darkfield oil (NA 1.20–1.40), for 20X–100XFluorescence Illuminator • Multi-purpose coded type (FN 22, 8-position mirror unit turret, 4-position ND slider)• Economical type (FN 26.5, 8-position mirror unit turret)Fluorescence Light Source 100 W mercury apo lamp housing and power supply unit, 100 W mercury lamp housing and power supply unit, or 130 W mercury light guide illuminationBX53 SPECIFICATIONS Specifications 15Microscope Frame Optical System UIS2 optical systemFocusVertical stage movement: 25 mm stage stroke with coarse adjustment limit stopper, torque adjustment for coarseadjustment knobs, stage mounting position variable, high sensitivity fine focusing knob (minimum adjustmentgradations: 1 μm)IlluminatorBuilt-in Koehler illumination for transmitted light, light intensity manager switchhigh color reproductivity 2 W LED light sourceRevolving Nosepiece Interchangeable reversed quintuple/coded quintuple/sextuple/septuple/coded sextuple/coded septuple nosepieceObservation Tube Widefield (FN 22)• Widefield tilting, telescopic and lifting binocular• Widefield tilting trinocular• Widefield trinocular• Widefield erect image trinocular• Widefield tilting binocular• Widefield ergo binocular• Widefield binocularSuper Widefield (FN 26.5)• Super widefield trinocular• Super widefield erect image tilting trinocularStage C eramic-coated coaxial stage with left or right hand low drive control: with rotating mechanism and torque adjustment mechanism, optional rubber grips and stage handle extension adaptor available (non stick grooved coaxial, plain, rotatable stages are also available)Condenser • Abbe (NA 1.1), for 4X–100X• Swing out Achromatic (NA 0.9), for 1.25X–100X (swing-out: 1.25X–4X)• Achromatic Aplanatic (NA 1.4), for 10X–100X• Phase contrast, darkfield (NA 1.1), [phase contrast: for 10X–100X, darkfield: for 10X–100X (up to NA 0.80)]• Universal (NA 0.9), for 1.25X–100X [swing-out: 1.25X–4X, with oil top lens:(NA 1.4)]• Low (NA 0.75), for 2X–100X (Dry)• Darkfield dry (NA 0.8–0.92), for 10X–100X• Darkfield oil (NA 1.20–1.40), for 20X–100XBX43 SPECIFICATIONSMicroscope Frame Optical System UIS2 optical systemFocusF ixed low stage nosepiece focus15 mm focus stroke with coarse adjustment limit stopTorque adjustment for coarse adjustment knobsHigh sensitivity fine focusing knob (adjustment gradations: 1 μm) IlluminatorBuilt-in Koehler illumination for transmitted light, light intensity manager switchHigh color reproductivity 2 W LED light sourceRevolving Nosepiece Fixed reversed coded quintuple nosepieceObservation Tube Widefield (FN 22)• Widefield tilting trinocular• Widefield trinocular• Widefield tilting binocular• Widefield tilting, telescopic, lifting binocular • Widefield ergo binocular• Widefield binocularStage C eramic-coated coaxial stage with left or right hand low drive control, rotating mechanism and torque adjustment mechanism (low torqe, plain, rotating stages are also available)Condenser B uilt-in condenser (NA 0.9) 1.25X–100X (swing out: 1.25X–2X) BX46 SPECIFICATIONSOperating Environment • Indoor use• Ambient temperature : 5˚ to 40˚C (41˚ to 104˚ F)• Maximum relative humidity : 80% for temperatures up to 31˚C (88˚F), decreasing linearly through 70% at 34˚C(93˚F), 60% at 37˚C (99˚F), to 50% relative humidity at 40˚C (104˚F)• Supply voltage fluctuations : not to exceed ±10 % of the normal voltageBX53/BX43/BX46 SPECIFICATIONS16BX63 FL DIMENSIONS(unit: mm)TOUCH PANEL CONTROLLER DIMENSIONS(unit: mm)BX3-CBH DIMENSIONS(unit: mm)BX53 DIMENSIONS(unit: mm)BX53 FL DIMENSIONS (unit: mm)BX43 DIMENSIONS (unit: mm)209.7*220BX46 DIMENSIONS (unit: mm)Dimensions17BX53+BX3-MDO18/MDO26 DIMENSIONS(unit: mm)BX53+U-MDO10 DIMENSIONS(unit: mm)BX53+U-DO DIMENSIONS (unit: mm)18Printed in Japan N8601578-102020Shinjuku Monolith, 2-3-1 Nishi-Shinjuku, Shinjuku-ku, Tokyo 163-0914, Japan•is ISO14001 certified.•is ISO9001 certified.•is ISO13485 certified.• Illumination devices for microscope have suggested lifetimes.Periodic inspections are required. Please visit our website for details.• All company and product names are registered trademarks and/or trademarks of their respective owners.• Images on the PC monitors are simulated.• Specifications and appearances are subject to change without any notice or obligation on the part of the manufacturer.。

解剖镜（三目）技术参数1.解剖镜（三目）1.1.解剖镜（三目），可实现透射、反射变倍观察，主机采用特种合金材料，保证高的热稳定性和长时间的高精度调焦1.2具备电动调焦驱动器，电动调焦可同时满足1.2.1电动调焦范围≥350mm1.2.2调焦立柱高度≥420mm1.2.3最大载荷≥10kg1.3通过移动式LCD控制元件进行电动操作，可同时满足1.3.1具有操纵杆、滚轮、按钮和触摸屏的一体式设计1.4变倍体外置电动控制器，与变倍体连接，需同时满足：1.4.1具有变倍体调节旋钮，通过触感反馈可变速调节变倍范围1.4.2实时显示变倍数值、分辨率数值1.5光学系统：采用无限远光学系统，物镜、目镜独立色差矫正设计。

*1.6电动变倍体，可同时满足1.6.1电动变焦比20.5：1，变焦范围0.78x～16.0x1.6.2采用10x目镜时，系统放大倍数：7.8x～160.0x*1.7具备透射光照明装置，可实现明场、暗场和斜照明（RC）观察，电动超薄底座*1.8漫反射环形落射光照明：LED可手动及软件控制调整照明效果,配有环形漫反射光罩,可伸缩1.9多维相衬透射光照明系统，可使包括无色透明标本的图像具有浮雕的立体感，提供了更高对比度，在本配套中实现明场、暗场、斜射、浮雕相称、以及多维组合的照明方式，符合各类实验样品的照明需求*1.10 1x平场复消色差物镜，最高分辨率525 lp/mm1.11观察镜筒：低眼点三目镜筒，宽视野10倍目镜、视场数≥23 mm，双眼屈光度可调节1.12平场复消色差物镜：1.12.1 平场复消色差≥1x倍高分辨率物镜，工作距离≥61mm (1x APO平场复消色差物镜)2落射明场照明系统2.1长寿命LED冷光源漫反射环形光照明系统，采用弥散照明方式，配有环形漫反射光罩,可伸缩无明亮反射光点2.3外置LED光源寿命≥50000小时3同品牌高分辨率彩色制冷型相机3.1彩色制冷型显微数码相机，芯片尺寸：1英寸* 3.2 2000万物理像素成像系统* 3.3 ）量子效率：64%@525nm3.4 传感器类型：彩色CCD3.5 单元像素大小：≥3.45 μm x 3.45 μm* 3.6)暗电流：-15ke-;(8)读出噪声：-4e; 像素下动态活图≥8-15 帧/秒3.7 大于等于四端口读出，USB3.0 高速传输3.8 冷却功能：具有芯片主动制冷4. 成像工作站及成像软件系统4.1 具备全面的图像管理功能：编档，标注，图像优化处理（色彩管理，自动暴光，亮度、对比度调节等）。

显微镜技术参数分包1：双目生物显微镜1台一、配置要求：显微镜主机、透射明场照明系统、平场消色差物镜4X—100X（4个）二、技术要求：2.1光学系统：无限远光学矫正系统，齐焦距离必须为国际标准45mm。

2.2载物台：钢丝传动，无齿条结构，尺寸为：120 x 132mm；行程为：76mm(X)x 30mm(Y）2.3调焦机构：有粗调限位，可以进行张力调节，避免标本或物镜的损伤。

2.4聚光镜：带有孔径光阑的阿贝聚光镜，N.A. 1.25，带有蓝色滤色片2.5照明系统：20000小时寿命LED光源2.6双目观察筒：瞳距调整范围48-75mm，倾斜角度30°，带屈光度调节，360°可旋转，铰链式，眼点高度≥432.9 mm，视场数≥20，目镜：10X，带眼罩，视场数≥202.7物镜转盘：与显微镜机身固定的内旋式4孔物镜转盘，便于放置标本等操作。

2.8物镜：平场消色差物镜4X（N.A.≥0.1 W.D≥27）、10X（N.A.≥0.25 W.D≥8）、40X （N.A.≥0.65 W.D≥0.6）、100X（N.A.≥1.25 W.D≥0.12）2.9防霉装置：在双目观察筒、目镜、物镜都做了防霉处理2.10所采用光学元件均为环保无铅玻璃分包2：三目生物显微镜2台一、配置要求：显微镜主机、透射明场照明系统、平场消色差物镜4X—100X（4个）荧光模块及其附属装置二、技术要求：2.1光学系统：无限远光学矫正系统，齐焦距离必须为国际标准45mm。

2.2载物台：钢丝传动，无齿条结构，载物台距离桌面不高于140mm，便于双手平放在桌面操作，最大限度减轻疲劳，机械固定载物台, (W × D): 211 mm × 154 mm，移动范围 (X ×Y): 76 mm × 52 mm，载物台XY 移动可锁定。

2.3调焦机构：载物台高度调节 ( 粗调: 15 mm )，可以进行张力调节；有粗调限位，避免标本或物镜的损伤；细调焦旋钮最小调节幅度: 2.5 μm。

丹酚酸B通过抗氧化作用改善高脂饮食小鼠牙槽骨骨质疏松的实验研究王丽丽;牛建昭;高思华;张东伟;马如风;于娜;刘海霞;朱如愿;柳辰玥;张淑静;高誉珊;葛东宇【摘要】目的探索丹酚酸B改善高脂饮食引起的小鼠牙槽骨骨量丢失的作用以及可能的作用机制.方法 C57 BL/6J雄性小鼠30只,分为3组:正常组、高脂饮食组和丹酚酸B组,每组10只.除正常组外,其他两组给予高脂饮食,丹酚酸B组用丹酚酸B[125 mg/(kg·d)]干预,治疗12w后,取小鼠牙槽骨,然后分别用双能X射线测量骨密度,HE染色观察骨微结构,免疫组织化学染色分析牙槽骨核因子-κB-p65(nuclear factor-kappa B,NF-κB-p65)、组织蛋白酶K(Cathepsin K)、超氧化物歧化酶(superoxide dismutase,SOD)和NADPH oxidase 4 (Nox4)的表达情况.结果丹酚酸B能明显改善高脂饮食诱发的小鼠牙槽骨骨密度下降以及骨微结构破坏.同时,丹酚酸B能上调高脂饮食小鼠牙槽骨SOD的表达,下调Nox4、NF-κB-p65和Cathepsin K的表达.结论丹酚酸B可能通过调节Nox4/SOD/NF-κB/Cathepsin K通路改善高脂饮食引起的氧化应激,从而抑制高脂饮食诱发的小鼠牙槽骨骨量丢失.本研究将为丹参及其有效成分治疗骨质疏松提供科学的实验依据.%Objective This study is aimed to assess the effect of salvianolic acid B (Sal-B) on high fat diet (HFD)-induced mandibular bone loss and to identify the potential signaling pathway involved in this process.Methods Thirty C57BL/6J male mice were randomly divided into 3 groups,normal group,HFD group and Sal-B group,with 10 mice in each group.All the mice except that in normal group were treated with high fat diet.Mice in Sal-B group received Sal-B [125 mg/(kg·d)] for 12 weeks.The effects of Sal-B on bone mineral density(BMD) and micro-structures were evaluated using dual energy X-ray absorptiometry and hematoxylin and eosin staining.The expressions of nuclear factor-kappa B (NF-κB)-p65,Cathepsin K,superoxide dismutase (SOD),and NADPH oxidase 4 (Nox4) in mandibles were determined with immunohistochemical staining.Results Sal-B treatment reversed the disorganized mandible bone micro-structures and descending BMD in HFD mice.Sal-B also up-regulated the expression of SOD and down-regulated the expression of Nox4,NF-κB-p65,and Cathepsin K in the mandibles triggered by HFD.Conclusion Sal-B treatment prevents the HFD-induced oxidative stress by regulating Nox4/SOD/NF-κB/Cathepsin K signaling pathway,and inhibits mandible osteoporosis.Our finding may offer a new source to discover the applications of salvia miltiorrhiza and its constituents for the treatment of osteoporosis.【期刊名称】《中国骨质疏松杂志》【年(卷),期】2017(023)003【总页数】6页(P281-285,317)【关键词】丹酚酸B;小鼠牙槽骨;高脂饮食;骨质疏松;动物实验【作者】王丽丽;牛建昭;高思华;张东伟;马如风;于娜;刘海霞;朱如愿;柳辰玥;张淑静;高誉珊;葛东宇【作者单位】北京中医药大学基础医学院,北京100029;北京中医药大学基础医学院,北京100029;北京中医药大学糖尿病研究中心,北京100029;北京中医药大学糖尿病研究中心,北京100029;北京中医药大学基础医学院,北京100029;北京中医药大学基础医学院,北京100029;北京中医药大学基础医学院,北京100029;北京中医药大学基础医学院,北京100029;北京中医药大学中药学院,北京100029;北京中医药大学基础医学院,北京100029;北京中医药大学基础医学院,北京100029;北京中医药大学基础医学院,北京100029【正文语种】中文【中图分类】R361;R965.1长期的高脂饮食可能导致骨吸收增加，骨形成减少[1]，最终诱发下颌骨骨量丢失，发生骨质疏松[2]。