Other Early Developments 1
1982: • Term “AIDS” coined • First cases in women reported • First transfusion and vertically transmitted cases reported 1983: • Isolation of a retrovirus from a patient with AIDS by
Acquired Immune Deficiency syndrome(AIDS)
THE SECOND AFFILIATED HOSPITAL, CQUMS ZHOU ZHI 周智
Definition
AIDS is a fatal chronic infectious disease caused by the Human Immunodeficiency Virus(HIV), transmitted mainly through sexual contacts and body fluids, characterized pathologically by selective depletion of helper T(CD4+) lymphocytes and impairment of cell-mediated immunity, and clinically by severe opportunistic infections and malignancies.
Etiology
Classification: HIV-1 and HIV-2, belong to family Retroviridae, subfamily Lentivirus, and were discovered in 1983 and 1985, respectively.