肺复张治疗急性Stanford A型主动脉夹层术后低氧血症

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Medical University,Shanghai 200433 ,China
[Abstract] 0bjective:To study clinical effectiveness and possible side effects with lung recruitment on
hypoxemia after surgery in patients with acute Stanford A aortic dissection in early stage.M ethods:Twenty f ive patients with hypoxemia after surgery for acute Stanford A aortic dissection were included from October 201 1 to
fbrd A aortic dissection L/U Yang,TANG Yandeng,LI Bailin,ZHENG Yanhua,ZHOU Wei,CHEN Changx— ing,TANG Xiaojun,XU Zhiyun Department of Cardiothoracic Surgery,Changhai Hospital,Second Military
肺 复 张 治疗 急 性 Stanford A型 主 动 脉 夹 层 术 后 低 氧 血症
刘 洋 唐杨 烽 李 白翎 郑艳 华 周 炜 陈常 兴 唐 小军 徐 志云
[摘 要 ] 目的 :评价 肺复 张术对于 改善急性 Stanford A型 主动脉夹层 术后早 期低 氧血症 的疗效 。 方法 :2011年 10月至 2013年 1月 ,急性 Stanford A型主动脉 夹层术后 发生低氧血症 (以术后 24h内氧合 指数 <150 mmHg为标准 ,1mmHg=0.133kPa)患 者 25例 ,男性 20例 ,女 性 5例 ,年龄 31~61岁 ,平 均 (46.0±9.2)岁。持续监测有创血压 、经 皮血 氧饱和 度 、心率 ,按 照理 想体质 量给 予小潮 气量肺 保护 通 气 ,结合 呼吸末正压 (PEEP)递 增法进 行肺 复张术 。于复 张前后 进行 动脉血 气分 析及监 测静态 肺顺 应 (Cs)。结果 :全部患者肺复张后 PaO:、PaO:/FiO 及 cs较复张前差异有统计学 意义 (P<0.05),第 2次 肺复张后 PaO /FiO 较第 1次复张后差异有统计学意义 (P<0.05)。所有 患者均无气 压伤 或其他严 重 并发症发生 。结论 :肺保护性通气结合肺复 张策略 可 以有 效改善急 性 A型 主动脉夹 层术后 低氧血症 , 在最大 PEEP不超过 20 cmH:O(1cmH20=0.098kPa)的情况下 ,肺 复张是安 全的且对循环影响较小。
PaO2/FiO2 and Cs were increased significantly after applying recr u itment maneuvers in a ll 25 cases. PaO2/FiO2 were increased signif icantly a fter applying second recr uitment maneuvers than after applying first recruitment maneuvers. All patients had no barotraum a,or other serious com plications.C onclusion :Lung protective venti— lation combined with lung recruitment strategy can effectively improve hypoxemia after surgery for acute type A
[关键词 ] 肺复张 ;Stanford A型主动脉夹层 ;低氧血症 ;术后 [中图分 类号 ] R543 [文献标志码] A [文章编号 ] 1007-5062(2014)02.190-04
Treatment efect of lung recruitm ent maneuver on hypoxem ia after surgery in patients with acute Stan·
Januar y 2013.There were 20 male and 5 female with an average age of46.0 years(31—61years).Patients
with oxygenation index less than 150 within first postoperative 24 hours to be included in the study.Continuous monitoring of invasive blood pressure,transcutaneous oxygen saturation,hear t rate,according to idea l body weight low tidal volume were given for lung protective ventilation,and Recruitment maneuvers were conducted by
心 肺 血 管 病 杂 志 2014年 3月 第 33卷第 2期 Journal of Cardiovascular& Pulmonary Diseases.March 2014.V01.33.No.2

DOI:10.3969/j.issn.1007-5062.2014.02.012
临 床 论 著 ·
stepwise rising of positive end expiratory pressure(PEEP)leve1.Ar ter ial blood gas a na lysis(ABG)a n d static compliance of lung(Cs)were measured before and after applying recr uitment maneuvers. Results:PaO2,