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HUANG Renhua1 SHEN Jialin2 LU Qing2 YAN Junrong2 XIE Huaying1 BAI Yongrui1▲ 1.Department of Chemotherapy, Renji Hospital Affiliated to Medical College of Shanghai Jiaotong University, Shanghai 200127, China; 2.Department of Radiology, Renji Hospital Affiliated to Medical College of Shanghai Jiaotong University, Shanghai 200127, China [Abstract] Objective To evaluate the values of diffusion weighted imaging (DWI) in the differential diagnosis of brain glioma and brain metastatic. Methods 38 cases of brain space occupying, 20 cases of brain glioma (WHO, grade Ⅲ10 cases, grade Ⅳ 20 cases, all cases were confirmed histologically) and 18 cases of brain metastases were collected. All the pa tients were given normal MRI examination and DWI examination. Value of ADC of tumor area, the surrounding area of tu mor and normal control area were measured. Value of normalized ADC of tumor area (rADC-t)=value of ADC of tumor area/value of ADC of normal control area; value of normalized ADC of the surrounding area of tumor (rADC-p)=value of ADC of the surrounding area of tumor/value of ADC of normal control area. Results DWI test shown low signal levels in liquefy and necrosis areas of brain gliomas and brain metastases. In 20 cases of brain glioma, ADC values of tumor area and the surrounding area of tumor were higher than that of normal control area, and all groups had statistically significant (all P < 0.05); in 18 cases of brain metastases, ADC values of tumor area and the surrounding area of tumor were higher than the value of c normal control area, and all groups hadstatistically significant (all P < 0.05). There were no statistical differences in rADC-t between brain gliomas and brain meta value of brain gliomas was significantly less than the value of brain metastases, and two groups of value had a significant difference ( P < 0.05). Conclusion DWI can be used to identify brain glioma and brain metastases, and provide the best clinical treatment. [Key words] Brain gliomas; Diffusion-weighted imaging; Brain metastases
且差异均有统计学意义（均 P < 0.05）。 胶质瘤与脑转移瘤 rADC-t 值比较，差异无统计学意义（P > 0.05）。 胶质瘤的
rADC-p 值明显低于脑转移瘤 ，且差异有统计学意义 （P < 0.05）。 结论 DWI 可以用来帮助鉴别脑胶质瘤与脑转移
瘤，从而为临床提供最佳的治疗方案。
[关键词] 脑胶质瘤；弥散加权成像；脑转移瘤
体 ADC 值/对侧正常区 ADC 值；瘤旁水肿区的标准化 ADC 值（rADC-p）=瘤旁水肿区 ADC 值/对侧正常区 ADC 值。
结果 脑胶质瘤与脑转移瘤的液化坏死区 DWI 上均呈低信号。 20 例胶质瘤瘤体及瘤旁水肿区的 ADC 值均高于对侧
正常组织，且差异均有统计学意义（均 P < 0.05）。 18 例脑转移瘤瘤体及瘤旁水肿区的 ADC 值均高于对侧正常组织，
2012 年 11 月第 9 卷第 33 期
· 影像与介入 ·
Ｄ ＷＩ 在脑胶质瘤与脑转移瘤鉴别诊断中的应用
黄仁华 1 沈加林 2 路 青 2 闫俊荣 2 谢华英 1 白永瑞 1▲ 1.上海交通大学医学院附属仁济医院放疗科，上海 200127；2.上海交通大学医学院附属仁济医院放射科，上海 200127
[摘要] 目的 评价弥散加权成像（DWI）在脑胶质瘤与脑转移瘤诊断和鉴别诊断中的应用价值 。 方法 收集 38 例脑
内占位病例，20 例脑胶质瘤（WHO 分级Ⅲ级 10 例，Ⅳ级 10 例，均经手术病理证实 ），18 例脑转移瘤，所有患者均行
MRI 常规检查和 DWI 检查。 测量瘤体、瘤旁水肿区及对侧正常区的 ADC 值，瘤体区的标准化 ADC 值（rADC-t）=瘤
[中图分类号] R445.2; R739.41
[文献标识码] A
[文章编号] 1673-7210（2012）11（c）-0093-03
Application of DWI in the differential diagnosis of brain glioma and brain metastases
