CIR化妆品原料安全使用指南072018

化妆品使用安全操作规程1. 前言本文档旨在为化妆品使用者提供一份安全操作规程，以确保他们正确使用化妆品并减少潜在风险。

在使用化妆品前，请仔细阅读并遵守以下规程。

2. 选择合适的化妆品在购买化妆品前，应仔细阅读产品标签和说明书，并确保其符合个人需要和肤质。

选择合适的化妆品能够最大程度地减少过敏和不良反应的风险。

3. 保持清洁在使用化妆品前，请确保面部和双手的清洁。

使用洁面皂和温水清洁面部，用肥皂和水清洁双手。

这样能够减少污染和细菌的传播，有助于保持肌肤健康。

4. 使用适量使用化妆品时，应控制使用量。

大量使用化妆品并不会增强效果，反而可能造成过敏和皮肤问题。

遵守产品说明中建议的使用量是十分重要的。

5. 避开干燥区域避免在皮肤干燥的区域使用化妆品，特别是对于干燥的皮肤类型。

如果您的皮肤有干燥问题，建议先涂抹保湿霜或控制使用化妆品的频率，以避免进一步伤害皮肤。

6. 避免过敏原在使用化妆品时，请避免接触到已知的过敏原。

如果对某种成分过敏或有任何不良反应，请立即停止使用该产品，并咨询专业医生或皮肤科医生的意见。

7. 存储和保养化妆品正确存储和保养化妆品是确保其质量和安全的关键。

请注意以下要点：- 将化妆品存放在干燥、阴凉和避免阳光直射的地方。

- 不与其他化学物质或家庭清洁剂存放在一起，以避免化学反应。

- 确保化妆品瓶盖紧闭，以防止污染和变质。

8. 涉及眼部的特别注意事项对于眼部化妆品的使用，我们需要格外谨慎。

以下是需要注意的要点：- 使用专为眼部使用的化妆品。

- 在使用眼线笔、眼影等产品时，确保它们不会与眼球直接接触。

- 不与他人共用眼部化妆品。

- 如果感到任何不适或发现眼部问题，请立即停止使用并咨询眼科医生的意见。

9. 外出后的化妆品使用在户外活动或在面临日常污染的环境中，使用化妆品的注意事项如下：- 使用具有防晒功能的化妆品以保护肌肤免受紫外线的伤害。

- 使用遮瑕膏或粉底来遮盖肌肤上的瑕疵，但不要过度使用。

化妆品原料安全性技术手册(MSDS)概述化妆品原料安全性技术手册（MSDS）是一份详细描述化妆品原料安全性信息的技术手册。

该手册旨在提供有关化妆品原料的物理化学性质、危害特性、安全操作建议以及急救措施等信息，以帮助使用者了解并正确使用化妆品原料。

内容化妆品原料安全性技术手册（MSDS）通常包含以下内容：1. 原料信息：列出化妆品原料的通用名称、化学名称、化学结构以及其他标识信息。

2. 物理化学性质：描述原料的外观、颜色、气味、溶解性、熔点、沸点等物理化学性质。

3. 危害特性：详细说明原料可能具有的危害特性，如刺激性、腐蚀性、毒性等，并提供相关的危害等级和标识。

4. 安全操作建议：提供使用化妆品原料时的安全操作建议，包括必要的个人防护措施、通风要求、储存要求等。

5. 急救措施：指导在发生事故或接触原料后应采取的急救措施，包括眼部冲洗、皮肤洗净、吸入处理等。

6. 法规信息：列出与该原料相关的法规和标准，以指导使用者遵守相关法规要求。

目的和重要性化妆品原料安全性技术手册（MSDS）的编制和提供是为了保障使用者的安全。

通过提供详尽的安全性信息和操作建议，帮助使用者正确使用化妆品原料，避免事故发生，降低潜在风险。

此外，化妆品原料安全性技术手册（MSDS）也是符合法规要求的重要文件。

许多国家和地区的法规要求化妆品原料供应商提供该手册，以确保产品的安全性和合规性。

结论化妆品原料安全性技术手册（MSDS）是一份重要的技术文件，提供了关于化妆品原料的安全性信息和操作建议。

使用者应仔细阅读并遵守手册中的安全操作要求，以确保化妆品原料的安全使用。

同时，供应商也应及时更新和提供最新的手册，以满足法规要求并保障用户的安全。

Cosmetic ingredients found safe as used (1374 total, through July 2011)Ingredient#"As used" concentration for safe as usedconclusionAcacia Senegal Gum and Acacia Senegal Gum Extract 2 up to 9%Acetic Acid 1 up to 0.3%Acetylated Lanolin 1 up to 7%Acetylated Lanolin Alcohol 1 up to 16%Acetyl Tributyl Citrate 1 up to 7%Acetyl Triethyl Citrate 1 up to 7%Acetyl Trihexyl Citrate 1 not in use at the time*Acetyl Trioctyl Citrate 1 not in use at the time*Acrylates/Dimethiconol Acrylate Copolymer (Dimethiconol and its Esters and Reaction Products) 1 up to 0.5%Actinidia Chinensis (Kiwi) Seed Oil 1 up to 0.1%Adansonia Digitata Oil 1 up to 0.01%Adansonia Digitata Seed Oil 1 not in use at the time*Adipic Acid (Dicarboxylic Acids and their Salts and Esters) 1 0.000001% in leave on; 18% in rinse off4 up to 99%Alcohol Denat. denatured with t-Butyl Alcohol, Denatonium Benzoate, Diethyl Phthalate, or MethylAlcoholAleurites Moluccanus Bakoly Seed Oil 1 not in use at the time*Aleurities Moluccana Seed Oil 1 0.00001 to 5%Allantoin 1 up to 2%Allantoin Ascorbate 1 up to 0.05%Allantoin Biotin and Allantoin Galacturonic Acid 2 not in use at the time*Allantoin Glycyrrhetinic Acid, Allantoin Panthenol, and Allantoin Polygalacturonic Acid 3 concentration not reported*Alumnina Magnesium Silicate 1 up to 0.01%Alumnium Calcium Silicate 1 up to 6%Aluminum Dimyristate 1 up to 3%Aluminum Distearate 1 up to 5%Aluminum Iron Silicates 1 not in use at the time*13 not in use at the time*Aluminum Isostearates/Myristates, Calcium Myristate, Decyl Myristate, Ethylhexyl Myristate, EthylMyristate, Glyceryl Dimyristate, Glyceryl Isostearate/Myristate, Isostearyl Myristate, IsotridecylMyristate, Methyl Myristate, Oleyl Myristate, Tetradecyloctadecyl Myristate, Tridecyl MyristateAluminum Myristate 1 up to 1%Alumnium Myristates/Palmitates 1 up to 6%Aluminum Silicate 1 up to 37% in dentifrices; up to 3% in other usesAluminum Stearate 1 up to 8%Aluminum Tristearate 1 up to 10%Amaranthus Hypochondriacus Seed Oil 1 not in use at the time*Amino Bispropyl Dimethicone 1 not in use at the time*5-Amino-4-Chloro-o-Cresol 1 up to 2% in oxidative and non-oxidative hair dyes5-Amino-6-Chloro-o-Cresol 1 up to 2% in oxidative and non-oxidative hair dyes4-Amino-m-Cresol 1 up to 0.7% in oxidative and non-oxidative hair dyes6-Amino-m-Cresol 1 up to 2.4% in oxidative and non-oxidative hair dyes6-Amino-o-Cresol 1 up to 0.7% in oxidative hair dyes; insufficient data foruse in non-oxidative hair dyes4-Amino-2-Hydroxytoluene 1 up to 5%Aminomethyl Propanediol 1 up to 2%Aminomethyl Propanol 1 up to 7%2-Amino-3-Nitrophenol 1 up to 2%concentration not reported*2-Amino-4-Nitrophenol 1 2-Amino-4-Nitrophenol Sulfate 1 not in use at the time*2-Amino-5-Nitrophenol 1 not in use at the time*Cosmetic Ingredient Review, 1101 17th Street, NW, Suite 310, Washington, DC 20036 ph 202.331.0651 fax 202.331.0088 email info@Ingredient#"As used" concentration for safe as usedconclusion4-Amino-3-Nitrophenol 1 up to 9%m-Aminophenol 1 up to 5%o-Aminophenol 1 up to 1%p-Aminophenol 1 up to 1%Aminopropyl Dimethicone 1 not in use at the time*Ammonium Bisulfite 1 up to 32%Ammonium Capryleth Sulfate, Ammonium c12-15 Pareth Sulfate, Ammonium Myreth Sulfate,10 not in use at the time*Magnesium Coceth Sulfate, Magnesium Myreth Sulfate, Sodium C10-15 Pareth Sulfate, SodiumC12-13 Pareth Sulfate, Dodium Deceth Sulfate, Sodium Laneth Sulfate, Zinc Coceth SulfateAmmonium Cocomonoglyceride Sulfate, Coconut Oil Decyl Esters, Decyl Cocoate, Hydrogenated11 not in use at the time*Coco-Glycerides, Isodecyl Cocoate, Lauryl Cocoate, Octyldodecyl Cocoate, PotassiumHydrogenated Cocoate, Sodium Cocomonoglyceride Sulfate, Sodium Hydrogenated Cocoate, andTridecyl Cocoate9 not in use at the time*Ammonium Coco-Sulfate, Ammonium Myristyl Sulfate, Magnesium Coco-Sulfate, SodiumCoco/Hydrogenated Tallow Sulfate, Sodium Ethylhexyl Sulfate, Sodium Oleyl Sulfate, SodiumTallow Sulfate, Sodium Tridecyl Sulfate, Zinc Coco-SulfateAmmonium Cumenesulfonate 1 not in use at the time*Ammonium Glycyrrhizate 1 up to 5%Ammonium Laureth Sulfate 1 up to 36%Ammonium Stearate 1 up to 10%Ammonium Sulfite 1 not in use at the time*Ammonium Tallate 1 not in use at the time*Ammonium Xylenesulfonate 1 up to 3%Amodimethicone 1 up to 3%Amodimethicone Hydroxystearate 1 not in use at the time*Amyl Acetate 1 up to 10%Amyl Benzoate 1 not in use at the time*Anacardium Occidentale (Cashew) Seed Oil 1 0.002 to 1%Arachidyl Glycol 1 not in use at the time*Arachidyl Propionate 1 up to 10%Arachis Hypogaea (Peanut) Oil 1 0.0001 to 30%Arctium Lappa Seed Oil 1 not in use at the time*Argania Spinosa Kernel Oil 1 0.001 to 10%Ascorbic Acid 1 up to 35% (formulated to be non-irritating) Ascorbyl Dipalmitate 1 not in use at the time*Ascorbyl Palmitate 1 up to 0.2%Ascorbyl Stearate 1 not in use at the time*Astragalus Gummifer Gum (aka Tragacanth (Astragalus Gummifer) Gum) 1 up to 3%Astrocaryum Murumuru Seed Butter 1 0.001 to 7%Attapulgite 1 up to 8%Avena Sativa (Oat) Kernel Oil 1 0.002 to 0.005%Avocado Oil (aka Persea Gratissima (Avocado) Oil) 1 0.0001 to 98%Azelaic Acid (Dicarboxylic Acids and their Salts and Esters) 1 up to 0.3% in leave on; 10% in rinse off Babassu Acid 1 not in use at the time*Basic Blue 99 1 up to 2%Bassia Butyracea Seed Butter 1 not in use at the time*Bassia Latifolia Seed Butter 1 0.001 to 2%Beeswax 1 up to 56%Behenoxy Dimethicone 1 up to 3%Behenyl Alcohol 1 up to 50%Behenyl Benzoate 1 not in use at the time*Cosmetic Ingredient Review, 1101 17th Street, NW, Suite 310, Washington, DC 20036 ph 202.331.0651 fax 202.331.0088 email info@Ingredient#"As used" concentration for safe as usedconclusionBentonite 1 12-80% in mud packs; up to 8% for other uses Benzaldehyde 1 up to 0.5%Benzophenone-1 1 up to 2%Benzophenone-2 1 up to 6%Benzophenone-3 1 up to 7%Benzophenone-4 1 up to 2.5%Benzophenone-5, -6 2 up to 0.3%Benzophenone-8 1 up to 0.2%Benzophenone-9 1 up to 0.4%Benzophenone-11 1 up to 0.2%Benzylparaben 1 up to 0.4% if used alone (paraben mixes up to 0.8%) Bertholletia Excelsa Seed Oil 1 0.0003 to 0.5%BHA (aka Butylated Hydroxyanisole) 1 up to 0.2%BHT (Butylated Hydroxytoluene) 1 up to 0.5%Biotin 1 up to 1%Bisabolol 1 up to 1%N,N-Bis(2-Hydroxyethyl)-p- Phenylenediamine Sulfate 1 up to 5%Borago Officinalis Seed Oil 1 0.001 to 1%Brassica Campestris (Rapeseed) Oil Unsaponifiables 1 not in use at the time*Brassica Campestris (Rapeseed) Seed Oil 1 0.007 to 17%Brassica Napus Seed Oil 1 not in use at the time*Brassica Oleracea Acephala Seed Oil 1 not in use at the time*Brassica Oleracea Italica (Broccoli) Seed Oil 1 0.001 to 3%n-Butane (aka Butane) 1 up to 92%1,2-Butanediol 1 not in use at the time*Butoxyethyl Acetate 1 not in use at the time*Butyl Acetate 1 up to 72%t-Butyl Acetate 1 Up to 10%n-Butyl Alcohol 1 up to 15% in nail products and 0.002% in otherproductst-Butyl Alcohol 1 up to 0.5%Butyl Benzoate 1 not in use at the time*Butyl Benzyl Phthalate 1 not in use at the time*50%Butylene Glycol 1 >Butylene Glycol Cocoate 1 up to 2%Butylene Glycol Diisononanoate 1 17%Butyl Ester of PVM/MA Copolymer 1 up to 14%Butyl Myristate 1 concentration not reported*Butyloctyl Benzoate 1 not in use at the time*Butylparaben 1 up to 0.4% if used alone (paraben mixes up to 0.8%) Butyl Stearate 1 up to 9%Butyrospermum Parkii (Shea) Butter 1 0.0005 to 60%Butyrospermum Parkii (Shea) Butter Unsaponifiables 1 0.06 to 3%Butyrospermum Parkii (Shea) Oil 1 0.01 to 15%C12-15 Alkyl Benzoate 1 0.0008-59%C14-18 Glycol 1 not in use at the time*C15-18 Glycol 1 concentration not reported*C16-17 Alkyl Benzoate 1 concentration not reported*C18-30 Glycol 1 not in use at the time*C20-30 Glycol 1 not in use at the time*Cosmetic Ingredient Review, 1101 17th Street, NW, Suite 310, Washington, DC 20036 ph 202.331.0651 fax 202.331.0088 email info@Ingredient#"As used" concentration for safe as usedconclusionC30-45 Alkyl Dimethicone 1 2%C24-28 Alkyl Methicone 1 not in use at the time*C30-45 Alkyl Methicone 1 not in use at the time*Calcium Acetate 1 concentration not reported*Calcium Ascorbate 1 not in use at the time*Calcium Carboxymethyl Cellulose 1 not in use at the time*Calcium Disodium EDTA 1 not in use at the time*Calcium Silicate 1 up to 10%Calcium Sodium PVM/MA Copolymer 1 concentration not reported*Calcium Stearate 1 up to 23%Calcium Xylenesulfonate 1 not in use at the time*Calendula Officinalis Extract 1 not in use at the time*Calendula Officinalis Flower 1 not in use at the time*Calendula Officinalis Flower Extract 1 up to 6%Calendula Officinalis Flower Oil 1 up to 0.1%Calendula Officinalis Seed Oil 1 not in use at the time*Camelina Sativa Seed Oil 1 0.002 to 1%Camellia Japonica Seed Oil 1 0.01 to 0.2%Camellia Kissi Seed Oil 1 0.1 to 10%Camellia Oleifera Seed Oil 1 0.003 to 3%Camellia Sinensis Seed Oil 1 up to 0.1%Canarium Indicum Seed Oil 1 not in use at the time*Canola Oil 1 0.0002 to 73%Canola Oil Unsaponifiables 1 up to 0.001%Caprylic/Capric Triglyceride 1 up to 84%Caprylic/Capric/Coco Glycerides 1 up to 4%Caprylyl Glycol 1 0.00003 – 5%Carbomer-910, -962 2 not in use at the time*Carbomer-934, -934P, -940, -941 4 up to 2%Carica Papaya Seed Oil 1 up to 0.1%Carthamus Tinctorius (Safflower) Seed Oil 1 0.00005 to 84%Carya Illinoensis (Pecan) Seed Oil 1 not in use at the time*Caryocar Brasiliense Fruit Oil 1 0.0005-0.2Cellobiose Octanonanoate 1 not in use at the time*Cellulose 1 up to 88%Cellulose Acetate 1 up to 2%Cellulose Acetate Butyrate 1 up to 15%Cellulose Acetate Propionate 1 not in use at the time*Cellulose Gum 1 up to 20%Cellulose Succinate 1 not in use at the time*Ceresin 1 up to 20%Cetearyl Alcohol 1 up to 25%Cetearyl Isononanoate 1 up to 50%Cetearyl Methicone 1 up to 1%Cetearyl Nononoate 1 up to 3%Cetearyl Octanoate (aka Cetearyl Ethylhexanoate) 1 up to 25%Cetyl Acetate 1 up to 17%Cetyl Alcohol 1 up to 50%Cetyl Dimethicone 1 up to 10%Cetyl Esters 1 up to 7%Cosmetic Ingredient Review, 1101 17th Street, NW, Suite 310, Washington, DC 20036 ph 202.331.0651 fax 202.331.0088 email info@Ingredient#"As used" concentration for safe as usedconclusionCetyl Glycol 1 not in use at the time*Cetyl Hydroxyethylcellulose 1 up to 2%Cetyl Isononanoate 1 up to 5%Cetyl Myristate 1 up to 6%Cetyl Palmitate 1 up to 11%Cetyl Ricinoleate 1 up to 10%Cetyl Stearate 1 up to 15%Chenopodium Quinoa Seed Oil 1 up to 0.3%4-Chloro-2-Aminophenol 1 safe as used in oxidative hair dyes, but not in use atthe time*; insufficient data for use in non-oxidativehair dyes2-Chloro-p-Phenylenediamine 1 up to 0.1%2-Chloro-p-Phenylenediamine Sulfate 1 up to 1.0%4-Chlororesorcinol 1 ≤1% in hair dyesChloroxylenol 1 up to 0.5%Cholesterol 1 up to 3%Cholesteryl Nonanoate 1 up to 30%Choleth-24 1 up to 5% topicalCitrullus Lanatus (Watermelon) Seed Oil 1 up to 2%Citrus Aurantifolia (Lime) Seed Oil 1 not in use at the time*Citrus Aurantifolia (Lime) Seed Oil Unsaponifiables 1 not in use at the time*Citrus Aurantium Dulcis (Orange) Seed Oil 1 not in use at the time*Citrus Aurantium Dulcis (Orange) Seed Oil Unsaponifiables 1 not in use at the time*Citrus Grandis (Grapefruit) Seed Oil 1 not in use at the time*Citrus Grandis (Grapefruit) Seed Oil Unsaponifiables 1 not in use at the time*Citrus Limon (Lemon) Seed Oil 1 1 to 5%Citrus Paradisi (Grapefruit) Seed Oil 1 0.01 to 20%Cocoamphoacetate (aka Sodium Cocoamphoacetate) 1 up to 10%Cocoamphodiacetate (aka Disodium Cocoamphodiacetate) 1 up to 50%Cocoamphodipropionate (aka Disodium Cocoamphodipropionate) 1 up to 25%Cocoamphopropionate (aka Sodium Cocoamphopropionate) 1 not in use at the time*Cocoglycerides 1 up to 14%Coconut Acid 1 0.03 to 14%Coconut Alcohol 1 up to 0.9%Cocos Nucifera (Coconut) Oil 1 0.0001 to 80%Cocos Nucifera (Coconut) Seed Butter 1 not in use at the time*Coix Lacryma-Jobi (Job’s Tears) Seed Oil 1 not in use at the time*Copernicia Cerifera (Carnauba) Wax 1 up to 20%Corn Acid 1 not in use at the time*Corn Glycerides 1 not in use at the time*Corylus Americana (Hazel) Seed Oil 1 concentration not reported*Corylus Avellana (Hazel) Seed Oil 1 0.005 to 98%Cottonseed Acid 1 not in use at the time*Crambe Abyssinica Seed Oil 1 concentration not reported*Cucumis Sativus (Cucumber) Seed Oil 1 concentration not reported*Cucurbita Pepo (Pumpkin) Seed Oil 1 0.003 to 0.1%Cyclomethicone 1 up to 89%Cycloheptasiloxane 1 concentration not reported* Cyclohexasiloxane 1 up to 48%Cyclopentasiloxane 1 up to 93%Cosmetic Ingredient Review, 1101 17th Street, NW, Suite 310, Washington, DC 20036 ph 202.331.0651 fax 202.331.0088 email info@Ingredient#"As used" concentration for safe as usedconclusionCyclotetrasiloxane 1 up to 28%Cynara Cardunculus Seed Oil 1 not in use at the time*Decylene Glycol 1 concentration not reported*Decyl Oleate 1 up to 88%Decyl Succinate (Dicarboxylic Acids and their Salts and Esters) 1 not in use at the time*Dehydroacetic Acid 1 up to 0.7%Denatonium Benzoate 1 1/16 avoidupois ounce per 100 gal alcohol2,4-Diaminophenoxyethanol Dihydrochloride and 2,4-Diaminophenoxyethanol Sulfate 2 up to 2%Diammonium EDTA 1 not in use at the time*Dibehenyl Fumarate 1 not in use at the time*Dibutyl Adipate (Dicarboxylic Acids and their Salts and Esters) 1 concentration currently not reported;* previouslyreported up to 8%Dibutyloctyl Sebacate (Dicarboxylic Acids and their Salts and Esters) 1 not in use at the time*Dibutyl Phthalate 1 up to 15%Dibutyl Sebacate (Dicarboxylic Acids and their Salts and Esters) 1 not in use at the time*Di-C12-15 Alkyl Adipate (Dicarboxylic Acids and their Salts and Esters) 1 not in use at the time*Di-C12-15 Alkyl Fumarate 1 up to 5%Dicapryl Adipate (Dicarboxylic Acids and their Salts and Esters) 1 concentration not reported*Dicaprylyl/Capryl Sebacate (Dicarboxylic Acids and their Salts and Esters) 1 not in use at the time*Dicapryl Succinate (Dicarboxylic Acids and their Salts and Esters) 1 concentration not reported*Dicetearyl Dimer Dilinoleate 1 up to 7%Dicetearyl Succinate (Dicarboxylic Acids and their Salts and Esters) 1 not in use at the time*Dicetyl Adipate (Dicarboxylic Acids and their Salts and Esters) 1 not in use at the time*Diethyl Adipate (Dicarboxylic Acids and their Salts and Esters) 1 not in use at the time*Diethylene Glycol Diethylhexanoate/Diisononanoate 1 up to 19%Diethylene Glycol Diisononanoate 1 not in use at the time*Diethylhexyl Adipate (aka Dioctyl Adipate) (Dicarboxylic Acids and their Salts and Esters) 1 up to 14% in leave on; 0.6% in rinse off Diethylhexyl Dimer Dilinoleate (aka Dioctyl Dimer Dilinoleate) 1 up to 12%Diethylhexyl Fumarate 1 not in use at the time*Diethylhexyl Sodium Sulfosuccinate (aka Dioctyl Sodium Sulfosuccinate) 1 ≤5%Diethylhexyl Sebacate (Dicarboxylic Acids and their Salts and Esters) 1 Up to 5% in leave on; 1% in rinse off Diethylhexyl Succinate (Dicarboxylic Acids and their Salts and Esters) 1 Up to 6% in leave on; 5% in rinse offDiethyl Malonate (Dicarboxylic Acids and their Salts and Esters) 1 Up to 0.02% in leave on; 0.01% in rinse off Diethyl Phthalate 1 up to 2%Diethyl Sebacate (Dicarboxylic Acids and their Salts and Esters) 1 Up to 1.5% in leave onDiethyl Succinate (Dicarboxylic Acids and their Salts and Esters) 1 not in use at the time*Diheptylundecyl Adipate (Dicarboxylic Acids and their Salts and Esters) 1 Up to 6% in leave onDihexyl Adipate (Dicarboxylic Acids and their Salts and Esters) 1 concentration in leave on not reported;* up to 3% inrinse offDihexyldecyl Adipate (Dicarboxylic Acids and their Salts and Esters) 1 not in use at the time*Dihexyldecyl Sebacate (Dicarboxylic Acids and their Salts and Esters) 1 not in use at the time*Dihydrochoesteryl Nonanoate 1 not in use at the time*Diisobutyl Adipate (Dicarboxylic Acids and their Salts and Esters) 1 not in use at the time*Diisobutyl Glutarate (Dicarboxylic Acids and their Salts and Esters) 1 not in use at the time*Diisobutyl Succinate (Dicarboxylic Acids and their Salts and Esters) 1 not in use at the time*Diisocetyl Adipate (Dicarboxylic Acids and their Salts and Esters) 1 not in use at the time*Diisocetyl Dodecanedioate (Dicarboxylic Acids and their Salts and Esters) 1 Up to 7% in leave onDiisodecyl Adipate (Dicarboxylic Acids and their Salts and Esters) 1 concentration in leave on not reported* Diisononyl Adipate (Dicarboxylic Acids and their Salts and Esters) 1 not in use at the time*Disooctyl Adipate (Dicarboxylic Acids and their Salts and Esters) 1 not in use at the time*Cosmetic Ingredient Review, 1101 17th Street, NW, Suite 310, Washington, DC 20036 ph 202.331.0651 fax 202.331.0088 email info@Ingredient#"As used" concentration for safe as usedconclusionDiisooctyl Sebacate (Dicarboxylic Acids and their Salts and Esters) 1 Up to 3% in leave onDiisopropyl Adipate (Dicarboxylic Acids and their Salts and Esters) 1 up to 7% in leave on; 8% in rinse offDiisopropyl Dimer Dilinoleate 1 up to 53%Diisopropyl Sebacate (Dicarboxylic Acids and their Salts and Esters) 1 Up to 10% in leave on; 2% in rinse off Diisostearyl Adipate (Dicarboxylic Acids and their Salts and Esters) 1 Up to 10% in leave on; 3% in rinse off Diisostearyl Dimer Dilinoleate 1 up to 12%Diisostearyl Fumarate 1 up to 20%Diisostearyl Glutarate (Dicarboxylic Acids and their Salts and Esters) 1 not in use at the time*Diisostearyl Sebacate (Dicarboxylic Acids and their Salts and Esters) 1 not in use at the time*Dimethicone 1 up to 80% in hair preparations; up to 24% in makeup Dimethicone Copolyol** 0 up to 1%Dimethicone PEG-7 Phosphate and Dimethicone PEG-8 Benzoate (aka Dimethicone Copolyol) 2 up to 0.5%3 concentration not reported*Dimethicone PEG-10 Phosphate,Dimethicone PEG-6 Acetate,and Dimethicone PEG-8 Adipate (aka Dimethicone Copolyol)3 not in use at the time*Dimethicone PEG/PPG-7/4 Phosphate,Dimethicone PEG/PPG-12/4 Phosphate,and Dimethicone PEG/PPG-20/23 Benzoate (aka Dimethicone Copolyol)Dimethiconol (Dimethiconol and its Esters and Reaction Products) 1 Up to 36%Dimethiconol Arginine (Dimethiconol and its Esters and Reaction Products) 1 not in use at the time*Dimethiconol Beeswax (Dimethiconol and its Esters and Reaction Products) 1 Up to 0.9%Dimethiconol Behenate (Dimethiconol and its Esters and Reaction Products) 1 Up to 0.5%Dimethiconol Borageate (Dimethiconol and its Esters and Reaction Products) 1 not in use at the time*Dimethiconol Candelillate (Dimethiconol and its Esters and Reaction Products) 1 not in use at the time*Dimethiconol Carnaubate (Dimethiconol and its Esters and Reaction Products) 1 not in use at the time*Dimethiconol Cysteine (Dimethiconol and its Esters and Reaction Products) 1 Up to 0.07%Dimethiconol Dhupa Butterate (Dimethiconol and its Esters and Reaction Products) 1 not in use at the time*Dimethiconol Hydroxystearate (Dimethiconol and its Esters and Reaction Products) 1 not in use at the time*Dimethiconol Illipe Butterate (Dimethiconol and its Esters and Reaction Products) 1 not in use at the time*Dimethiconol Isostearate (Dimethiconol and its Esters and Reaction Products) 1 not in use at the time*Dimethiconol Kokum Butterate (Dimethiconol and its Esters and Reaction Products) 1 not in use at the time*Dimethiconol Lactate (Dimethiconol and its Esters and Reaction Products) 1 not in use at the time*Dimethiconol Meadowfoamate (Dimethiconol and its Esters and Reaction Products) 1 Up to 1%Dimethiconol Methionine (Dimethiconol and its Esters and Reaction Products) 1 concentration not reported*1 not in use at the time*Dimethiconol/Methylsilanol/Silicate Crosspolymer (Dimethiconol and its Esters and ReactionProducts)Dimethiconol Mohwa Butterate (Dimethiconol and its Esters and Reaction Products) 1 not in use at the time*Dimethiconol Panthenol (Dimethiconol and its Esters and Reaction Products) 1 Up to 0.07%Dimethiconol Sal Butterate (Dimethiconol and its Esters and Reaction Products) 1 not in use at the time*Dimethiconol/Silica Crosspolymer (Dimethiconol and its Esters and Reaction Products) 1 not in use at the time*Dimethiconol/Silsesquioxane Copolymer (Dimethiconol and its Esters and Reaction Products) 1 Up to 0.3%1 not in use at the time*Dimethiconol/Stearyl Methicone/Phenyl Trimethicone Copolymer (Dimethiconol and its Esters andReaction Products)Dimethiconol Stearate (Dimethiconol and its Esters and Reaction Products) 1 Up to 1%Dimethoxysilyl Ethylenediaminopropyl Dimethicone 1 not in use at the time in non-coloring hair careproducts*Dimethyl Adipate (Dicarboxylic Acids and their Salts and Esters) 1 Up to 0.2% in rinse offDimethyl Glutarate (Dicarboxylic Acids and their Salts and Esters) 1 Up to 15% in rinse offDimethyl Lauramine, Dimethyl Myristamine, Dimethyl Palmitamine, Dimethyl Behenamine,8 not in use at the time*Dimethyl Cocamine, Dimethyl Hydrogenated Tallowamine, Dimethyl Tallowamine, DimethylSoyamineDimethyl Phthalate 1 up to 2%Cosmetic Ingredient Review, 1101 17th Street, NW, Suite 310, Washington, DC 20036 ph 202.331.0651 fax 202.331.0088 email info@Ingredient#"As used" concentration for safe as usedconclusionDimethyl Stearamine 1 up to 4% in non-coloring hair care products Dimethyl Succinate (Dicarboxylic Acids and their Salts and Esters) 1 not in use at the time*Dioctyl Adipate(aka Diethylhexyl Adipate) 0 up to 38%Dioctyl Dimer Dilinoleate (aka Diethylhexyl Dimer Dilinoleate) 0 up to 12%Dioctyldodecyl Adipate (Dicarboxylic Acids and their Salts and Esters) 1 concentration in leave on not reported* Dioctyldodecyl Dodecanedioate (Dicarboxylic Acids and their Salts and Esters) 1 Up to 6% in leave onDioctyldocecyl Dimer Dilinoleate 1 up to 10%Dioctyldodecyl Sebacate (Dicarboxylic Acids and their Salts and Esters) 1 Up to 8% in leave onDioctyl Sodium Sulfosuccinate (aka Diethylgexyl Sodium Sulfosuccinate) 0 ≤5%Dioleyl Tocopheryl Methylsilanol 1 ≤6%Dioscorea Villosa (Wild Yam) Root Extract (aka Wild Yam (DV) Extract 1 up to 15% of max. 2% plant solids Dipentaerythrityl Pentaisononanoate 1 up to 13%Dipotassium Azelate (Dicarboxylic Acids and their Salts and Esters) 1 not in use at the time*Dipotassium EDTA 1 less than 0.1%Dipotassium Glycyrrhizate 1 up to 1%Dipropyl Adipate (Dicarboxylic Acids and their Salts and Esters) 1 not in use at the time*Dipropylene Glycol 1 up to 50%Disodium Azelate (Dicarboxylic Acids and their Salts and Esters) 1 not in use at the time*Disodium EDTA 1 less than 1%Disodium Glycyrrhizate 1 not in use at the time*Disodium Fumarate 1 not in use at the time*Disodium Sebacate (Dicarboxylic Acids and their Salts and Esters) 1 not in use at the time*Disodium Succinate (Dicarboxylic Acids and their Salts and Esters) 1 up to 0.4% in leave on; 0.0005% in rinse off Disodium Succinoyl Glycyrrhizate 1 concentration not reported*Disperse Black 9 1 0.3 - 0.5% in hair coloring productsDisperse Violet 1 1 up to 0.7%Ditridecyl Adipate (Dicarboxylic Acids and their Salts and Esters) 1 not in use at the time*Ditridecyl Dimer Dilinoleate 1 not in use at the time*DMDM Hydantoin 1 up to 1%Dodecanedioic Acid (Dicarboxylic Acids and their Salts and Esters) 1 not in use at the time*Drometrizole 1 0.07%EDTA 1 up to 2%Elaeis Guineensis (Palm) Butter 1 not in use at the time*Elaeis Guineensis (Palm) Kernel Oil 1 0.05 to 23%Elaeis Guineensis (Palm) Oil 1 0.002 to 48%Elaeis Oleifera Kernel Oil 1 concentration not reported*Elaeis (Palm) Fruit Oil 1 not in use at the time*Emulsifying Wax N.F. 1 up to 21%Erythorbic Acid 1 up to 1%Ethoxydiglycol 1 up to 80%Ethyl Acetate 1 up to 85%Ethyl Benzoate 1 0.0008-0.01%Ethylcellulose 1 up to 4%Ethyl Ester of PVM/MA Copolymer 1 up to 30%Ethyl Hexanediol 1 ≤5%Ethylhexyl Benzoate 1 3 to 4%Ethylhexyl Cocoate 1 up to 41%Ethylhexyl Isononanoate 1 up to 75%Ethylhexyl Palmitate (aka Octyl Palmitate) 1 up to 46%Cosmetic Ingredient Review, 1101 17th Street, NW, Suite 310, Washington, DC 20036 ph 202.331.0651 fax 202.331.0088 email info@Ingredient#"As used" concentration for safe as usedconclusionEthylhexyl Pelargonate 1 up to 25%Ethylhexyl Stearate (aka Octyl Stearate) 1 up to 11%Ethylparaben 1 up to 0.4% if used alone (paraben mixes up to 0.8%)4 not in use at the time*Ethyl Pelargonate, Isobutyl Pelargonate, Methyl Pelargonate,Neopentyl Glycol Dicaprylate/Dipelargonate/DicaprateEthyl Ricinoleate 1 not in use at the time*Euphorbia Cerifera (Candelilla) Wax 1 up to 27%Euterpe Oleracea Fruit Oil 1 0.00001 to 0.5%Ferrous Fumarate 1 up to 0.0003%Fragaria Ananassa (Strawberry) Seed Oil 1 not in use at the time*Fragaria Chiloensis (Strawberry Seed Oil 1 not in use at the time*Fragaria Vesca (Strawberry) Seed Oil 1 not in use at the time*Fragaria Virginiana (Strawberry) Seed Oil 1 not in use at the time*Fuller’s Earth 1 up to 50%Fumaric Acid 1 up to 5%Garcinia Indica Seed Butter 1 0.1 to 2%Gevuina Avellana Seed Oil 1 0.1 to 2%Gevuina Avellana Oil 1 0.002 to 0.2%Glutaric Acid (Dicarboxylic Acids and their Salts and Esters) 1 not in use at the time*Glycereth-7 Diisononanoate 1 not in use at the time*Glyceryl Adipate 1 not in use at the time*Glyceryl Alginate and Glyceryl Erucate 2 up to 0.5%Glyceryl Arachidate 1 not in use at the time*Glyceryl Behenate 1 up to 5%Glyceryl Caprate 1 not in use at the time*reported*Glyceryl Caprylate 1 notGlyceryl Caprylate/Caprate 1 up to 2%Glyceryl Citrate/Lactate/ Linoleate/ Oleate 1 not in use at the time*Glyceryl Cocoate 1 up to 5%Glyceryl Collagenate 1 not in use at the time*Glyceryl Glycyrrhetinate 1 not in use at the time*Glyceryl Hydrogenated Rosinate 1 not in use at the time*Glyceryl Hydrogenated Soyate 1 not in use at the time*Glyceryl Hydroxystearate 1 up to 2%Glyceryl Isopalmitate 1 not in use at the time*Glyceryl Isostearate 1 up to 6%Glyceryl Isostearates 1 not in use at the time*Glyceryl Isostearate/Myristate 1 not in use at the time*Glyceryl Isotridecanoate/Stearate/ Adipate 1 not in use at the time*Glyceryl Lanolate 1 not in use at the time*Glyceryl Laurate 1 up to 4%Glyceryl Laurate/Oleate, Glyceryl Laurate SE, and Glyceryl Oleate SE 3 not in use at the time*Glyceryl Linoleate and Glyceryl Linolenate 2 up to 1%Glyceryl Montanate 1 not in use at the time*Glyceryl Myristate 1 concentration not reported*Glyceryl Oleate 1 up to 5%Glyceryl Oleate/Elaidate 1 up to 2%Glyceryl Palmitate 1 concentration not reported*Glyceryl Palmitate/Stearate and Glyceryl Palmitoeleate 2 not in use at the time*Glyceryl Pentadecanoate 1 not in use at the time*Cosmetic Ingredient Review, 1101 17th Street, NW, Suite 310, Washington, DC 20036 ph 202.331.0651 fax 202.331.0088 email info@。

化妆品行业化妆品质量安全操作规程化妆品是人们日常生活中常用的产品之一，质量安全是保障使用者健康的重要因素。

为了规范化妆品行业的生产和销售，制定相应的操作规程是必不可少的。

本文将介绍化妆品行业常用的化妆品质量安全操作规程。

一、原料采购与质检化妆品的质量安全始于原料的采购环节。

化妆品生产企业应确保原料供应商符合相关法律法规的要求，并与其建立长期合作关系。

在原料采购过程中，应进行严格的质检，确保原料的质量和安全性符合标准。

质检应包括对原料的外观、气味、PH值、重金属含量等进行测试。

二、生产过程控制1. 厂房布局与环境控制化妆品生产厂房应具备良好的通风设施和洁净空间，有利于生产过程的安全和质量控制。

同时，在厂房内应设置一定数量和功能的消防器材，以确保发生火灾时能够及时扑灭。

2. 生产工艺与设备化妆品生产工艺应合理设计，确保每一道工序的操作要求明确，并进行相应的复核和记录。

生产设备应定期进行检测和维护，以确保其运行的稳定性和安全性。

3. 权威监测与检验化妆品生产企业应委托权威机构对产品进行监测和检验，确保产品的质量和安全性达到国家相关标准和规定。

监测与检验的项目应包括微生物检测、重金属含量检测等。

三、储存与运输1. 包装与标识化妆品出厂前应对产品进行规范的包装，并配有相应的标签和说明书。

标签和说明书上应清楚标注产品的名称、成分、使用方法、生产日期等信息。

2. 储存要求化妆品在储存过程中，应避免受潮、受热、受阳光直射等，以防止其质量受损。

同时，化妆品的储存场所应具备良好的通风和防火设施。

3. 运输环节控制化妆品的运输应使用封闭式运输工具，避免与其他有毒有害物质接触。

在运输过程中，应注意保持适当的温度和湿度，防止产品受到损坏。

四、产品检测与跟踪化妆品生产企业应建立健全的产品检测和跟踪机制，对产品进行全面的抽样检验，确保产品质量安全。

同时，应建立客户投诉反馈渠道，及时处理和解决客户投诉，保障使用者权益。

五、员工培训与管理化妆品生产企业应加强员工培训，使每个员工都具备相关的操作技能和安全意识。

化妆品成分安全技术手册一、简介在当今社会，人们对化妆品的安全性越来越重视。

为了确保消费者的健康和安全，化妆品行业制定了一系列的安全规范与标准，其中就包括了化妆品成分的安全性评估和监管要求。

本手册将详细介绍化妆品成分的安全评估及其技术要求，以帮助企业制定安全的化妆品配方和生产流程。

二、化妆品成分的安全性评估1. 安全性评估的目的化妆品成分的安全性评估旨在评估化妆品在正常或合理使用条件下，对人体的无害性。

评估过程包括成分的毒理学评估、皮肤感受性评估、眼刺激性评估等，以便确定成分的安全使用浓度和使用限制。

2. 毒理学评估毒理学评估是化妆品成分安全性评估的核心环节。

它包括了急性毒性评估、亚慢性毒性评估、致敏性评估、致突变性评估等。

化妆品企业应该委托合格的机构对成分进行毒性测试，并按照国内外相关法规和标准进行评估。

3. 皮肤感受性评估化妆品成分应具有良好的皮肤耐受性。

皮肤感受性评估主要通过人体皮肤刺激实验和致敏实验进行。

这些实验旨在判断成分对皮肤的刺激性、致炎性和过敏性，以确保化妆品对消费者的皮肤不会产生不良反应。

4. 眼刺激性评估化妆品中的某些成分可能与眼球接触时引起刺激和充血等反应。

化妆品企业应确保在眼部接触时不会产生不良反应。

眼刺激性评估可以通过人体眼部刺激实验和角膜渗透性实验等进行。

三、化妆品成分安全监管要求1. 国内监管要求在中国，化妆品成分的安全评估与监管要求由国家药品监督管理局（NMPA）负责。

企业首先需要自行评估化妆品成分的安全性，并依据相关法规编写技术文件，然后向NMPA提交审批资料。

资料中应包括成分的安全性评估报告、化妆品生产工艺和质量控制的详细说明等。

2. 国际监管要求不同国家和地区对化妆品成分的安全评估与监管要求有所差异。

国际上较为广泛接受的监管机构包括欧洲联盟委员会（EU、COSING）、美国食品药品监督管理局（FDA）和国际化妆品协会（COLIPA）等。

企业进入不同国际市场，需要遵守当地的相关法规和标准，确保成分的安全性符合当地的要求。

附件1：化妆品安全风险评估指南（征求意见稿）目录1. 适用范围 (1)2. 基本原则与要求 (1)3.化妆品安全风险评估人员的要求 (2)4. 风险评估程序 (3)5.毒理学研究 (9)6.化妆品原料的风险评估 (12)7.化妆品产品的安全评价 (18)8. 安全风险评估报告 (21)9. 术语和释义 (21)化妆品安全风险评估指南为保证消费者的健康安全，识别和控制化妆品安全风险，制定本指南。

1. 适用范围适用于化妆品原料的风险评估和产品的安全评价，包括由原料或产品生产过程中不可避免带入的安全性风险物质的风险评估。

2. 基本原则与要求2.1化妆品一般可认为是各种原料的组合，原料的安全性是化妆品安全的前提条件。

化妆品的安全性评价应基于所有原料和风险物质的风险评估。

如果确认某些原料之间存在化学、生物学等相互作用的，应该对其产生的风险物质进行评估。

2.2化妆品安全性评价应以现有科学数据和相关信息为基础，遵循科学、公正、透明和个案处理的原则，在实施过程中应保证风险评估工作的独立性。

2.3化妆品的安全风险评估工作由具有相应资质的安全风险评估人员按照本指南的要求进行评价，并出具风险评估报告。

2.4化妆品产品的安全风险评估资料应当及时更新，并保留至最后一批上市产品保质期结束以后10年。

2.5化妆品安全风险评估报告结论不足以排除产品对人体健康存在风险的，应当采用传统毒理学试验方法进行产品安全性评价。

3.化妆品安全风险评估人员的要求化妆品安全风险评估人员应符合以下要求：3.1具有化妆品专业知识基础，了解化妆品生产过程和质量安全控制要求；3.2能够查阅和分析毒理学信息，具有分析、评价和解释毒理学数据的能力；3.3能够公平、客观的分析化妆品的安全性，在全面分析所有可获得的数据和暴露条件的基础上，开展风险评估工作；3.4应当具有医学、药学、化学、毒理学或者类似学科的专业基础，取得大学本科以上文凭或其他正式资格证明，并具有5年以上相关专业从业经历。

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文档下载后可定制随意修改，请根据实际需要进行相应的调整和使用，谢谢!并且，本店铺为大家提供各种各样类型的实用资料，如教育随笔、日记赏析、句子摘抄、古诗大全、经典美文、话题作文、工作总结、词语解析、文案摘录、其他资料等等，如想了解不同资料格式和写法，敬请关注!Download tips: This document is carefully compiled by theeditor.I hope that after you download them,they can help yousolve practical problems. The document can be customized andmodified after downloading,please adjust and use it according toactual needs, thank you!In addition, our shop provides you with various types ofpractical materials,such as educational essays, diaryappreciation,sentence excerpts,ancient poems,classic articles,topic composition,work summary,word parsing,copy excerpts,other materials and so on,want to know different data formats andwriting methods,please pay attention!化妆品原料数据使用指南起草说明一、前言在化妆品行业，原料的选择和使用是产品品质的关键。

附件9：化妆品用椰油酰胺丙基甜菜碱原料要求为规范化妆品原料技术要求,提高化妆品卫生质量安全,根据化妆品卫生规范规定,编写椰油酰胺丙基甜菜碱原料要求以下称要求,本要求针对性地规定了椰油酰胺丙基甜菜碱的安全性要求及检验方法,其他相关要求及检验方法按相应规定执行;1.基本信息名称椰油酰胺丙基甜菜碱;1.1.1INCI名称及其ID号COCAMIDOPROPYLBETAINEID：555;1.1.2INCI标准中文译名椰油酰胺丙基甜菜碱;1.1.3IUPAC名称系统命名法名称：椰油酰胺丙基二甲胺乙内酯1.1.4常见别名及缩写椰子油脂肪酰胺丙基二甲基氨基醋酸甜菜碱、CAPBCOCAMIDOPROPYLBETAINE;登记号1.2.1CAS登记号61789-40-0,83138-08-3,86438-79-1;1.2.2EINECS登记号263-058-8;结构式其中R为C8的烷基或烯烃基～18性状及理化常数本品为无色或浅黄色透明液体,几乎无气味,溶于水、乙醇和异丙醇,不溶于矿物油;本品由椰油制备得来,为多种脂肪酰胺丙基甜菜碱的混合物,以月桂酰胺丙基甜菜碱为主;市场产品多为水溶液,相对密度,活性物椰油酰胺丙基甜菜碱含量多为28～32％;2.技术要求使用目的及适用范围椰油酰胺丙基甜菜碱是一种刺激性较小的两性离子表面活性剂,可作为抗静电剂、头发调理剂、皮肤调理剂、清洁剂、稳泡剂以及粘度调节剂等使用;广泛用于化妆品中;限量要求应根据产品试剂使用情况,对以下指标进行必要的安全性风险评估分析,以保证产品在正常以及合理的、可预见的使用条件下,不会对人体健康产生安全危害;2.2.1使用限量要求应对椰油酰胺丙基甜菜碱在化妆品中最大允许使用浓度进行必要的安全性风险评估分析;2.2.2椰油酰胺丙基甜菜碱相关组分限量要求应对椰油酰胺丙基甜菜碱中椰油酰胺丙基二甲胺和单氯乙酸含量进行必要的安全性风险评估分析;其他安全性要求若椰油酰胺丙基甜菜碱与亚硝基化体系一同使用,应对配方进行必要的安全性风险评估分析;3.检验方法鉴别试验方法3.1.1取供试品15 g,加水至100ml,作为供试品溶液;取供试品溶液1滴,加三氯甲烷5ml,溴酚蓝试液5ml和稀盐酸1ml,激烈摇动混合时,三氯甲烷层呈黄色;3.1.2取上述供试品溶液1滴,加亚甲基蓝试液5ml,氢氧化钠试液1ml和三氯甲烷5ml,激烈摇动混合时,三氯甲烷层呈蓝紫色至红紫色;3.1.3取供试品1.5g,在105℃干燥4h,取0.5g加氧化钙1.0g加热,发生的气体,使润湿过的石蕊试纸变蓝;椰油酰胺丙基甜菜碱含量检验方法3.2.1仪器水浴锅：可控温90℃左右；酸度计：分度不大于,配有玻璃电极如231型和甘汞电极如232型,并配有电位滴定；电磁搅拌器：带包裹聚四氟乙烯的搅拌棒；半微量滴定管：10ml;3.2.2试剂①乙醚-正丁醇2:1混合溶液；无水乙醇无水乙醇-水1:1溶液；氯化钠水溶液,20%；盐酸,cHCl=1mol/L溶液；氢氧化钠标准滴定溶液,cNaOH=L②;3.2.3步骤用减量法称取8～10g精确至0.001g供试品于烧杯中,加入10ml水、15ml氯化钠溶液和20ml盐酸溶液;置水浴中加热至35℃~40℃,搅拌,使其充分反应,转移到250ml梨形分液漏斗中,并分别用20ml水、30ml乙醚-正丁醇2:1混合溶液冲洗烧杯,冲洗液并入分液漏斗中;加塞剧烈振荡至少1min注意泄压,充分静置分层后将下层水相放入第二个分液漏斗中,再加入30ml乙醚-正丁醇2:1混合溶液,重复萃取两次,将三次萃取的上层液收集后①《要求》检验方法中，所涉试剂除有规定外均为分析纯，试验用水均为纯化水。

化妆品行业原料安全使用指南引言:如今，随着人们对美的追求不断提升，化妆品行业正处于快速发展阶段。

然而，化妆品原料的安全使用无疑是保障消费者健康的重要环节。

本文将为各行业人士呈现一份详尽的化妆品行业原料安全使用指南。

第一节：了解化妆品原料的分类和来源1. 基础原料：包括水、油脂、乳化剂等，它们是构成化妆品的基础成分，必须符合国家相关规定并经过严格测试。

2. 功能性原料：如活性剂、抗菌剂、防腐剂等，提升了产品的性能和稳定性，但它们必须按照规定的浓度和使用方法使用。

3. 助剂：如香料、色素等，它们能提升产品的观感，但使用时需注意其对皮肤的刺激性以及相关的法规要求。

小节一：化妆品原料的安全性评估1. 确保原料供应商的可靠性：选择与正规渠道合作的供应商，并定期进行供应商评估，确保原料的质量和安全性。

2. 进行原料的组分分析：通过分析原料的组分，确保其不含有毒、有害或不合法的物质，并严格控制重金属、农药及其代谢物等残留物。

3. 进行原料的风险评估：根据原料的毒理学信息，评估其潜在风险，并确定合适的使用浓度和方法，以确保产品的安全性。

小节二：化妆品原料的合理使用1. 严格控制使用浓度：根据原料的毒性和皮肤对其的耐受性，严格控制使用浓度，避免对皮肤造成刺激和损伤。

2. 注重使用方法：对于易挥发、易氧化的原料，建议采用适当的封闭包装和避光措施，确保其在产品中的稳定性和安全性。

3. 遵循法规限制：严格遵循国家和地区关于化妆品原料使用的相关法规和限制，禁止使用违禁或有争议的原料。

小节三：化妆品原料的全程追溯1. 建立完善的原料追溯体系：与原料供应商建立合作，确保原料的来源可靠，并建立相应的追溯体系，追溯化妆品原料的全程信息。

2. 记录和保存相关信息：建立化妆品原料的档案，记录原料的采购信息、使用记录和检测结果等，定期进行审查和更新。

3. 定期进行风险评估和改进：定期对原料的风险进行评估，发现问题及时改进，并进行相应的调整和升级。