高分辨MRI在直肠癌中应用实例
- 格式:ppt
- 大小:36.45 MB
- 文档页数:20


《中外医学研究》第18卷 第34期(总第474期)2020年12月 医技与临床 Yijiyulinchuang- 81 -①厦门大学附属第一医院杏林分院 福建 厦门 3610003.0T高分辨MRI诊断直肠癌术前壁外脉管侵犯的临床分析陈渊明① 姜聪明①【摘要】 目的:探讨3.0T 高分辨磁共振成像(MRI)诊断直肠癌术前壁外脉管侵犯(EMVI)的临床价值。
方法:选取笔者所在医院2017年5月-2020年5月收治的100例直肠癌患者作为研究对象,所有患者均行手术治疗,术前行3.0T 高分辨MRI 诊断。
结果:100例直肠癌患者中,经病理诊断出EMVI 阳性14例,经3.0T 高分辨MRI 诊断出EMVI 阳性10例,以病理诊断结果为“金标准”,经3.0T 高分辨MRI 诊断EMVI 的灵敏度为57.14%,特异度为97.67%,准确度为92.00%,阳性预测值为80.00%,阴性预测值为93.33%,误诊率为2.32%,漏诊率为42.86%。
3.0T 高分辨MRI 诊断EMVI 的结果与病理诊断结果具有理想一致性(Kappa =0.623)。
结论:3.0T 高分辨MRI 诊断直肠癌术前EMVI 准确度较高,可为诊断工作提供科学依据,有临床应用价值。
【关键词】 直肠癌 壁外脉管侵犯 磁共振成像 诊断效能 doi:10.14033/ki.cfmr.2020.34.030文献标识码 B文章编号 1674-6805(2020)34-0081-03 Clinical Analysis of 3.0T High Resolution MRI in the Diagnosis of Preoperative Extramural Vascular Invasion of Rectal Cancer/CHEN Yuanming, JIANG Congming. //Chinese and Foreign Medical Research, 2020, 18(34): 81-83 [Abstract] Objective: To investigate the clinical value of 3.0T high resolution magnetic resonance imaging (MRI) in the diagnosis of preoperative extramural vascular invasion (EMVI) of rectal cancer. Method: A total of 100 patients with rectal cancer treated in our hospital from May 2017 to May 2020 were selected as the research objects. All patients underwent surgical treatment, and 3.0T high resolution MRI diagnosis was performed before operation. Result: Among 100 patients with rectal cancer, 14 cases were diagnosed as EMVI positive by pathology, and 10 cases were diagnosed as EMVI positive by 3.0T high resolution MRI. The pathological diagnosis result was taken as the “gold standard”, the sensitivity of 3.0T high-resolution MRI to diagnose EMVI was 57.14%, specificity was 97.67%, accuracy was 92.00%, positive predictive value was 80.00%, negative predictive value was 93.33%, the misdiagnosis rate was 2.32% and the missed diagnosis rate was 42.86%. The results of 3.0T high-resolution MRI diagnosis of EMVI and pathological diagnosis had ideal consistency (Kappa =0.623). Conclusion: 3.0T high resolution MRI is highly accurate in diagnosing rectal cancer before surgery, which can provide scientific basis for diagnosis and has clinical application value. [Key words] Rectal cancer Extramural vascular invasion Magnetic resonance imaging Diagnostic efficacy First-author ’s address: Xinglin Branch, The First Affiliated Hospital of Xiamen University, Xiamen 361000, China 直肠癌是消化系统常见恶性肿瘤,其病因复杂,发病率较高,大多患者确诊后均为中晚期,最终导致预后差、病死率高。
分析核磁影像在直肠癌诊断中的临床应用作者:刘晨阳来源:《医学食疗与健康》2019年第09期[摘要]目的:分析核磁影像在直肠癌诊断中的临床应用价值。
方法:回顾性分析2017年1月至2019年1月在本院实施诊治的52例直肠癌患者资料,根据其诊断的方式划入CT组和MRI组(n=26)。
在差异性的影像学检查方式下,比较患者的检出率、病理T分期符合率及患者的影像学特征。
结果:CT组临床诊断检出率为84.62%,MRI组患者临床诊断检出率为96.15%,数据间差距比较包含统计学意义(p<0.05)。
MRI组患者病理T分期符合率為96.15%,数据比较明显高于CT组患者诊断符合率80.77%,组间差距对比存在统计学意义(p<0.05)。
直肠癌患者在不同的分期状态下,其核磁影像特点也存在不同,可以将其作为患者病情判断的依据。
结果:核磁影像在直肠癌患者诊断中的应用,能够提升患者的临床诊断符合率,对直肠癌患者手术治疗方案的设计奠定良好基础,建议临床应用。
[关键词]核磁影像;直肠癌诊断;临床诊断[中图分类号]R445.2;R735.37 [文献标识码]A [文章编号]2096-5249(2019)15-0241-02直肠癌为临床治疗中常见的消化系统恶性肿瘤,其发生率较高。
早期对直肠癌患者的症状进行诊断,分期予以判断,能够对患者治疗方案的设计产生重要影响,改善其预后效果,降低患者死亡率。
文章回顾性分析2017年1月至2019年1月在本院实施诊治的52例直肠癌患者资料,在差异性的临床诊断方式下,评估核磁影像的临床诊断应用价值,现将数据整理如下。
1资料与方法1.1一般资料:回顾性分析2017年1月至2019年1月在本院实施诊治的52例直肠癌患者资料,根据其诊断的方式划入CT组和MRI组(n=26)。
CT组患者中男女数量占比为14:12,年龄范围43-78岁,均数值为(60.15±3.31)岁。
患者中T1期4例,T2期5例,T3期15例,T4期2例。
高分辨率MRI动态增强扫描在直肠癌术前TN分期及手术方式选取中的应用刘金玲1,林吉征1,苏晓1,曲雪廷2,张亮1*作者单位:1.青岛大学附属医院放射科,青岛266003;2.青岛市市立医院放射科,青岛266003*通信作者:张亮,E-mail:中图分类号:R445.2:R735.37文献标识码:A DOI:10.12015/issn.1674-8034.2021.01.008本文引用格式:刘金玲,林吉征,苏晓,等.高分辨率MRI动态增强扫描在直肠癌术前TN分期及手术方式选取中的应用[J].磁共振成像,2021,12(1):38-42.[摘要]目的探讨高分辨率MRI动态增强扫描在直肠癌术前TN分期及手术方式选取中的应用价值。
材料与方法回顾性分析本院经肠镜病理确诊的154例直肠癌患者,所有患者均于术前接受高分辨率MRI动态增强扫描并进行肿瘤TN分期,根据术前分期结果拟定手术方式,比较术前拟定手术方式与最终手术方式的差异。
结果154例直肠癌患者中,高分辨率MRI动态增强扫描对于直肠癌MRI表现T分期准确性为87.7%,N分期准确性为38.9%。
拟定术式与实际术式符合率为95.5%,差异无统计学意义(P=0.480),拟定术式与实际术式一致性很强(Kappa值=0.873)。
117例中高位直肠癌拟定手术方式与实际手术方式的符合率为98.2%,拟定术式与实际术式一致性很强(Kappa值=0.915)。
37例低位直肠癌拟定手术方式与实际手术方式符合率为86.5%,拟定术式与实际术式一致性较强(Kappa值=0.643)。
结论高分辨率MRI动态增强扫描对于直肠癌术前T分期的准确度、敏感度及特异度较高,与病理诊断相接近,拟定手术方式与实际手术方式一致性高,高分辨率MRI动态增强扫描对于直肠癌术前T分期及手术方式的选择有较高的临床应用价值。
[关键词]直肠癌;磁共振成像;高分辨率;肿瘤分期;动态增强;手术方式Application of high resolution dynamic enhanced MR scan in TN staging and operation mode selection of rectal cancer before operationLIU Jinling1,LIN Jizheng1,SU Xiao1,QU Xueting2,ZHANG Liang1*1Department of Radiology,Affiliated Hospital of Medical College,Qingdao University,Qingdao266003,China;2Department of Radiolo‐gy,Qingdao Municipal Hospital,Shandong Province,Qingdao266003,China*Correspondence to:Zhang L,E-mail:Received06Aug2020,Accepted20Nov2020;DOI:10.12015/issn.1674-8034.2021.01.008Cite this article as:Liu JL,Lin JZ,SU X,et al.Application of high resolution dynamic enhanced MR scan in TN staging and operation mode selection of rectal cancer before operation[J].Chin J Magn Reson Imaging,2021,12(1):38-42.Abstract Objective:To investigate the application value of high resolution MRI dynamic enhanced scan in TN staging and operation mode selection of rectal cancer before operation.Materials and Methods:A retrospective analysis was performed on154patients with rectal cancer confirmed by surgery and pathology in our hospital.All the patients received high resolution dynamic enhanced MR scan before surgery and underwent tumor TN staging.According to the results of preoperative staging,the operative method was proposed, and the difference between the preoperative planned and the final operative method was compared.Results:Among the154patients with rectal cancer,the accuracy of T staging and N staging by high resolution MRI was87.7%and38.9%,respectively,The coincidence rate between the proposed operation and the actual one was95.5%,with no statistically significant difference(P=0.480).The proposed operation and the actual one were highly consistent(Kappa value=0.873).The coincidence rate between the proposed surgical method and the actual surgical method was98.2%in117patients with medium and high rectal cancer,and the proposed surgical method was highly consistent with the actual surgical method(Kappa value=0.915).In37cases of low rectal cancer,the coincidence rate between the proposed operation method and the actual operation method was86.5%,and the proposed operation method was highly consistent with the actual operation method(Kappa value=0.643).Conclusions:High-resolution MRI dynamic enhancement scanning for sensitivity and accuracy of the preoperative T staging of rectal cancer specific degree is higher,and the pathological diagnosis phase close,to formulate the operation mode and the actual operation mode high consistency,high resolution MRI dynamic enhancement scanning for the preoperative T staging of rectal cancer and the selection of surgical procedure with high clinical application value.Key words rectal cancer;magnetic resonance imaging;high resolution;tumor stage;dynamic enhancement;surgical options直肠癌是最常见的消化道恶性肿瘤之一,发生于距肛缘15cm以内的直肠,发病率为40/10万,随着人们生活条件的改善,直肠癌的发病率也在逐年升高[1-4]。
多参数MRI在结直肠癌诊断中的应用价值1.核磁共振扫描核磁共振扫描(MRI)是一种无创性、无辐射的成像技术,对于CRC的诊断具有很高的敏感性和特异性。
MRI扫描可以得到高质量的结构影像图像,可以准确检测到肿瘤和肿瘤周围的正常结构,以及肿瘤的大小、位置、形态等信息。
MRI可以显示肿瘤周围的病理改变,如肿块、瘘管、细微结构、血流动力学等,有助于制定治疗方案。
2.功能MRI功能MRI(fMRI)是一种可以显示活动脑区与其他区域的负血氧素依赖性信号的成像技术,因此被广泛用于神经科学领域。
近年来,fMRI在癌症领域的应用也得到了广泛关注,并被证明是一种可靠的多参数MRI技术。
fMRI技术通常使用大量氧化铁分子,这些分子能与血红蛋白结合并在血液中循环。
活动脑区的血流量通常比非活动区域的血流量更高,在fMRI扫描中可以很好地描绘出来。
与CRC有关的fMRI技术主要用于对肿瘤周围组织的血流动力学评估,这有助于提高结直肠癌的准确性。
3.弥散加权成像弥散加权成像(DWI)是一种有效的多参数MRI技术,能够检测组织中水分子的分子扩散。
DWI技术主要用于评估结直肠癌及其转移的组织的结构和功能变化,如炎症反应、细胞增殖、脂质沉积等。
DWI可以对肿瘤的组织特征、边缘形态和淋巴结转移进行评估,因此它在CRC准确性诊断中起到关键作用。
4.磁共振波谱成像磁共振波谱成像(MRS)是一种可以用于检测肿瘤、神经退行性疾病、代谢和化学成分的非侵入性、无损伤的检查技术。
MRS技术可以提供有关代谢物浓度、分子结构和化学反应动力学的信息,因此有助于提高CRC的诊断准确性。
MRS检测主要评估结直肠癌组织的脂质、葡萄糖代谢和蛋白质峰值,可以检测肿瘤中的代谢异常,进一步证实肿瘤的细胞特性。
总之,多参数MRI在结直肠癌的准确性诊断和治疗规划中起到了至关重要的作用,它可以提供关键的结构、功能、代谢和化学成分信息,有助于提高结直肠癌的诊断准确性和治疗效果。