外文翻译----数字图像处理和模式识别技术关于检测癌症的应用

数字图像处理外文翻译参考文献(文档含中英文对照即英文原文和中文翻译)原文：Application Of Digital Image Processing In The MeasurementOf Casting Surface RoughnessAhstract- This paper presents a surface image acquisition system based on digital image processing technology. The image acquired by CCD is pre-processed through the procedure of image editing, image equalization, the image binary conversation and feature parameters extraction to achieve casting surface roughness measurement. The three-dimensional evaluation method is taken to obtain the evaluation parametersand the casting surface roughness based on feature parameters extraction. An automatic detection interface of casting surface roughness based on MA TLAB is compiled which can provide a solid foundation for the online and fast detection of casting surface roughness based on image processing technology.Keywords-casting surface; roughness measurement; image processing; feature parametersⅠ.INTRODUCTIONNowadays the demand for the quality and surface roughness of machining is highly increased, and the machine vision inspection based on image processing has become one of the hotspot of measuring technology in mechanical industry due to their advantages such as non-contact, fast speed, suitable precision, strong ability of anti-interference, etc [1,2]. As there is no laws about the casting surface and the range of roughness is wide, detection parameters just related to highly direction can not meet the current requirements of the development of the photoelectric technology, horizontal spacing or roughness also requires a quantitative representation. Therefore, the three-dimensional evaluation system of the casting surface roughness is established as the goal [3,4], surface roughness measurement based on image processing technology is presented. Image preprocessing is deduced through the image enhancement processing, the image binary conversation. The three-dimensional roughness evaluation based on the feature parameters is performed . An automatic detection interface of casting surface roughness based on MA TLAB is compiled which provides a solid foundation for the online and fast detection of casting surface roughness.II. CASTING SURFACE IMAGE ACQUISITION SYSTEMThe acquisition system is composed of the sample carrier, microscope, CCD camera, image acquisition card and the computer. Sample carrier is used to place tested castings. According to the experimental requirements, we can select a fixed carrier and the sample location can be manually transformed, or select curing specimens and the position of the sampling stage can be changed. Figure 1 shows the whole processing procedure.,Firstly,the detected castings should be placed in the illuminated backgrounds as far as possible, and then through regulating optical lens, setting the CCD camera resolution and exposure time, the pictures collected by CCD are saved to computer memory through the acquisition card. The image preprocessing and feature value extraction on casting surface based on corresponding software are followed. Finally the detecting result is output.III. CASTING SURFACE IMAGE PROCESSINGCasting surface image processing includes image editing, equalization processing, image enhancement and the image binary conversation,etc. The original and clipped images of the measured casting is given in Figure 2. In which a) presents the original image and b) shows the clipped image.A.Image EnhancementImage enhancement is a kind of processing method which can highlight certain image information according to some specific needs and weaken or remove some unwanted informations at the same time[5].In order to obtain more clearly contour of the casting surface equalization processing of the image namely the correction of the image histogram should be pre-processed before image segmentation processing. Figure 3 shows the original grayscale image and equalization processing image and their histograms. As shown in the figure, each gray level of the histogram has substantially the same pixel point and becomes more flat after gray equalization processing. The image appears more clearly after the correction and the contrast of the image is enhanced.Fig.2 Casting surface imageFig.3 Equalization processing imageB. Image SegmentationImage segmentation is the process of pixel classification in essence. It is a very important technology by threshold classification. The optimal threshold is attained through the instmction thresh = graythresh (II). Figure 4 shows the image of the binary conversation. The gray value of the black areas of the Image displays the portion of the contour less than the threshold (0.43137), while the white area shows the gray value greater than the threshold. The shadows and shading emerge in the bright region may be caused by noise or surface depression.Fig4 Binary conversationIV. ROUGHNESS PARAMETER EXTRACTIONIn order to detect the surface roughness, it is necessary to extract feature parameters of roughness. The average histogram and variance are parameters used to characterize the texture size of surface contour. While unit surface's peak area is parameter that can reflect the roughness of horizontal workpiece.And kurtosis parameter can both characterize the roughness of vertical direction and horizontal direction. Therefore, this paper establisheshistogram of the mean and variance, the unit surface's peak area and the steepness as the roughness evaluating parameters of the castings 3D assessment. Image preprocessing and feature extraction interface is compiled based on MATLAB. Figure 5 shows the detection interface of surface roughness. Image preprocessing of the clipped casting can be successfully achieved by this software, which includes image filtering, image enhancement, image segmentation and histogram equalization, and it can also display the extracted evaluation parameters of surface roughness.Fig.5 Automatic roughness measurement interfaceV. CONCLUSIONSThis paper investigates the casting surface roughness measuring method based on digital Image processing technology. The method is composed of image acquisition, image enhancement, the image binary conversation and the extraction of characteristic parameters of roughness casting surface. The interface of image preprocessing and the extraction of roughness evaluation parameters is compiled by MA TLAB which can provide a solid foundation for the online and fast detection of casting surface roughness.REFERENCE[1] Xu Deyan, Lin Zunqi. The optical surface roughness research pro gress and direction[1]. Optical instruments 1996, 18 (1): 32-37.[2] Wang Yujing. Turning surface roughness based on image measurement [D]. Harbin:Harbin University of Science and Technology[3] BRADLEY C. Automated surface roughness measurement[1]. The InternationalJournal of Advanced Manufacturing Technology ,2000,16(9) :668-674.[4] Li Chenggui, Li xing-shan, Qiang XI-FU 3D surface topography measurement method[J]. Aerospace measurement technology, 2000, 20(4): 2-10.[5] Liu He. Digital image processing and application [ M]. China Electric Power Press,2005译文：数字图像处理在铸件表面粗糙度测量中的应用摘要—本文提出了一种表面图像采集基于数字图像处理技术的系统。

利用图像处理技术进行肿瘤检测研究与应用引言肿瘤是严重威胁人类健康的疾病之一，早期发现和准确诊断对于治疗和预后意义重大。

近年来，随着图像处理技术的不断发展，越来越多的研究者开始利用图像处理技术来进行肿瘤检测研究与应用。

本文将介绍利用图像处理技术进行肿瘤检测的研究方法和应用实例，并探讨其潜在的发展前景。

研究方法利用图像处理技术进行肿瘤检测的研究方法主要包括图像获取、预处理、特征提取和分类识别四个步骤。

首先，通过各种图像采集设备如X射线、CT、MRI等，获取患者的肿瘤图像。

然后，对采集的图像进行预处理，如去噪、增强、几何校正等，以提高图像质量和减少噪声。

接下来，利用特征提取算法，从图像中提取出有助于肿瘤检测的特征。

最后，通过分类识别算法，将提取出的特征与已知的肿瘤特征进行比对，从而实现肿瘤的自动识别和检测。

应用实例1. 白细胞图像分析白细胞图像分析是利用图像处理技术进行肿瘤检测的常见应用之一。

通过对患者的白细胞图像进行预处理和特征提取，研究者可以得到一系列与肿瘤相关的特征，如细胞核形状、颜色、大小等。

通过将这些特征与已知的肿瘤特征进行比对，可以实现白细胞的肿瘤分类和分析。

这种方法可以用于早期肿瘤的筛查和监测，对于癌症的早期诊断和治疗具有重要意义。

2. 影像识别系统影像识别系统是另一个利用图像处理技术进行肿瘤检测的应用实例。

利用计算机视觉和机器学习算法，研究者可以设计出一套自动化的肿瘤检测系统。

该系统可以将采集到的肿瘤图像与已有的肿瘤样本进行比对，并给出相应的诊断结果。

这种系统不仅可以提高肿瘤检测的准确度和效率，还可以减轻医生的工作负担，提高临床诊断的水平和效果。

潜在发展前景利用图像处理技术进行肿瘤检测的研究和应用在医学领域具有广阔的前景。

随着图像处理技术的不断发展和算法的不断改进，肿瘤检测的准确度和效率将得到进一步提高。

未来，我们可以期待更加智能化和自动化的肿瘤检测系统的出现，这将有助于提高肿瘤早期发现的几率，提高患者的预后和生存率。

基于机器学习的医疗图像分析技术在癌症研究中的应用随着科技的发展，机器学习的应用已经逐渐成熟并被广泛应用在各行各业中。

在医疗领域，机器学习技术被用来辅助医生诊断、分析医疗图像、预测病情等方面。

而其中，基于机器学习的医疗图像分析技术在癌症研究中的应用则受到了越来越多的关注。

癌症是一种严重威胁人类健康的疾病，而医疗图像是癌症研究中常用的手段之一。

常见的医疗图像有X光片、核磁共振图像、超声波图像等，这些图像往往需要医生经过长时间的观察和比对才能做出正确的诊断和判断。

这一过程不仅耗费时间，而且存在一定的误判率，因此，通过机器学习技术来辅助医生进行医疗图像分析，可以提高准确率、缩短时间、减轻医生的工作负担。

在基于机器学习的医疗图像分析技术中，最主要的应用方式是分类。

分类即将医疗图像分为不同类别，例如良性和恶性。

这一分类过程一般需要先对医疗图像进行特征提取，再以提取出的特征作为输入，训练机器学习模型，最终得到分类结果。

其中，特征提取和模型训练都是非常重要的环节，两者的效果直接决定着最终的分类准确率。

特征提取是指从医疗图像中提取有用的特征，例如图像纹理、形状、密度等。

这些特征可以帮助机器学习模型更好地区分不同的图像类别。

常见的特征提取方法包括卷积神经网络和传统的计算机视觉算法等。

卷积神经网络是近年来发展非常迅速的一种深度学习算法，其在图像分类任务中表现出色，因此也被广泛应用于医疗图像分析任务中。

传统的计算机视觉算法则是从传统图像处理方法转化而来，具有训练速度快、可解释性好等优势。

模型训练则是指根据提取出的特征，训练机器学习模型来实现医疗图像分类。

常用的模型包括支持向量机、决策树、随机森林、深度学习模型等。

不同的模型具有不同的优缺点，在具体任务中需要综合考虑数据量、数据质量、计算资源等因素，选择最优的模型。

此外，模型的参数设置和调优也是模型训练中极为重要的环节，好的参数设置可以极大地提升模型的准确率和稳定性。

在实际的医疗图像分类任务中，把以上提到的特征提取和模型训练应用到实际的数据中，会遇到很多实际的困难。

医学图像处理与模式识别技术在癌症筛查中的应用随着科技的进步和医疗技术的不断发展，医学图像处理与模式识别技术在癌症筛查中的应用正逐渐受到重视。

癌症是一种常见而严重的疾病，早期诊断对治疗和预后至关重要。

在传统的癌症筛查中，医生主要依靠自己的经验和临床常识来进行诊断，但这种方法存在一定的主观性和误判的风险。

而医学图像处理与模式识别技术的引入，可以提高癌症筛查的准确性和效率，为早期发现和治疗提供更好的支持。

医学图像处理技术是指运用计算机科学和工程学的方法来处理和分析人体内部的医学图像。

医学图像包括X光片、磁共振成像（MRI）、计算机断层扫描（CT）等多种形式。

这些图像中蕴含着大量的医学信息，但由于其复杂性和多样性，人工仅靠肉眼观察往往难以发现潜在的异常情况。

医学图像处理技术能够通过增强图像对比度、去除干扰噪声、调整亮度与对比度等方式，使得医生能够更清晰地观察医学图像，提高观察效果。

同时，还可以自动化地提取和分析图像中的特征，辅助医生进行诊断和判断。

与医学图像处理技术相辅相成的是模式识别技术。

模式识别技术是一种研究如何使机器能够自动识别、分类和对图像进行判断的技术。

在癌症筛查中，模式识别技术可以通过对医学图像中的特征进行分析和提取，帮助医生自动识别和分类潜在的癌症病灶。

例如，通过对乳腺X光片进行数字化处理和特征提取，可以帮助医生判断是否存在乳腺肿块。

模式识别技术还可以将医学图像与大量的数据库进行对比分析，借助机器学习的方法，提高癌症预测的准确性和灵敏度。

医学图像处理与模式识别技术在癌症筛查中的应用具有很多优势。

首先，它能够提高筛查的准确性和效率，减少人为因素的影响。

医生的判断往往受到主观意识和个体经验的限制，而机器不同，它可以通过从海量的医学图像中学习和归纳，得出更为客观和准确的结论。

其次，该技术能够实现早期诊断和干预，提高治疗的成功率。

早期发现和治疗是治愈癌症的关键，而医学图像处理与模式识别技术可以在癌症发展的早期阶段就发现潜在的肿瘤，帮助医生尽早采取相应的诊疗措施。

Digital Image Processing1 IntroductionMany operators have been proposed for presenting a connected component n a digital image by a reduced amount of data or simplied shape. In general we have to state that the development, choice and modi_cation of such algorithms in practical applications are domain and task dependent, and there is no \best method". However, it is interesting to note that there are several equivalences between published methods and notions, and characterizing such equivalences or di_erences should be useful to categorize the broad diversity of published methods for skeletonization. Discussing equivalences is a main intention of this report.1.1 Categories of MethodsOne class of shape reduction operators is based on distance transforms. A distance skeleton is a subset of points of a given component such that every point of this subset represents the center of a maximal disc (labeled with the radius of this disc) contained in the given component. As an example in this _rst class of operators, this report discusses one method for calculating a distance skeleton using the d4 distance function which is appropriate to digitized pictures. A second class of operators produces median or center lines of the digital object in a non-iterative way. Normally such operators locate critical points _rst, and calculate a speci_ed path through the object by connecting these points.The third class of operators is characterized by iterative thinning. Historically, Listing [10] used already in 1862 the term linear skeleton for the result of a continuous deformation of the frontier of a connected subset of a Euclidean space without changing the connectivity of the original set, until only a set of lines and points remains. Many algorithms in image analysis are based on this general concept of thinning. The goal is a calculation of characteristic properties of digital objects which are not related to size or quantity. Methods should be independent from the position of a set in the plane or space, grid resolution (for digitizing this set) or the shape complexity of the given set. In the literature the term \thinning" is not usedin a unique interpretation besides that it always denotes a connectivity preserving reduction operation applied to digital images, involving iterations of transformations of speci_ed contour points into background points. A subset Q _ I of object points is reduced by a de_ned set D in one iteration, and the result Q0 = Q n D becomes Q for the next iteration. Topology-preserving skeletonization is a special case of thinning resulting in a connected set of digital arcs or curves. A digital curve is a path p =p0; p1; p2; :::; pn = q such that pi is a neighbor of pi 1, 1 _ i _ n, and p = q. A digital curve is called simple if each point pi has exactly two neighbors in this curve. A digital arc is a subset of a digital curve such that p 6= q. A point of a digital arc which has exactly one neighbor is called an end point of this arc. Within this third class of operators (thinning algorithms) we may classify with respect to algorithmic strategies: individual pixels are either removed in a sequential order or in parallel. For example, the often cited algorithm by Hilditch [5] is an iterative process of testing and deleting contour pixels sequentially in standard raster scan order. Another sequential algorithm by Pavlidis [12] uses the de_nition of multiple points and proceeds by contour following. Examples of parallel algorithms in this third class are reduction operators which transform contour points into background points. Di_erences between these parallel algorithms are typically de_ned by tests implemented to ensure connectedness in a local neighborhood. The notion of a simple point is of basic importance for thinning and it will be shown in this report that di_erent de_nitions of simple points are actually equivalent. Several publications characterize properties of a set D of points (to be turned from object points to background points) to ensure that connectivity of object and background remain unchanged. The report discusses some of these properties in order to justify parallel thinning algorithms.1.2 BasicsThe used notation follows [17]. A digital image I is a function de_ned on a discrete set C , which is called the carrier of the image. The elements of C are grid points or grid cells, and the elements (p; I(p)) of an image are pixels (2D case) or voxels (3D case). The range of a (scalar) image is f0; :::Gmaxg with Gmax _ 1. The range of a binary image is f0; 1g. We only use binary images I in this report. Let hIi be the set of all pixel locations with value 1, i.e. hIi = I 1(1). The image carrier is de_ned on an orthogonal grid in 2D or 3Dspace. There are two options: using the grid cell model a 2D pixel location p is a closed square (2-cell) in the Euclidean plane and a 3D pixel location is a closed cube (3-cell) in the Euclidean space, where edges are of length 1 and parallel to the coordinate axes, and centers have integer coordinates. As a second option, using the grid point model a 2D or 3D pixel location is a grid point.Two pixel locations p and q in the grid cell model are called 0-adjacent i_ p 6= q and they share at least one vertex (which is a 0-cell). Note that this speci_es 8-adjacency in 2D or 26-adjacency in 3D if the grid point model is used. Two pixel locations p and q in the grid cell model are called 1- adjacent i_ p 6= q and they share at least one edge (which is a 1-cell). Note that this speci_es 4-adjacency in 2D or 18-adjacency in 3D if the grid point model is used. Finally, two 3D pixel locations p and q in the grid cell model are called 2-adjacent i_ p 6= q and they share at least one face (which is a 2-cell). Note that this speci_es 6-adjacency if the grid point model is used. Any of these adjacency relations A_, _ 2 f0; 1; 2; 4; 6; 18; 26g, is irreexive and symmetric on an image carrier C. The _-neighborhood N_(p) of a pixel location p includes p and its _-adjacent pixel locations. Coordinates of 2D grid points are denoted by (i; j), with 1 _ i _ n and 1 _ j _ m; i; j are integers and n;m are the numbers of rows and columns of C. In 3Dwe use integer coordinates (i; j; k). Based on neighborhood relations we de_ne connectedness as usual: two points p; q 2 C are _-connected with respect to M _ C and neighborhood relation N_ i_ there is a sequence of points p = p0; p1; p2; :::; pn = q such that pi is an _-neighbor of pi 1, for 1 _ i _ n, and all points on this sequence are either in M or all in the complement of M. A subset M _ C of an image carrier is called _-connected i_ M is not empty and all points in M are pairwise _-connected with respect to set M. An _-component of a subset S of C is a maximal _-connected subset of S. The study of connectivity in digital images has been introduced in [15]. It follows that any set hIi consists of a number of _-components. In case of the grid cell model, a component is the union of closed squares (2D case) or closed cubes (3D case). The boundary of a 2-cell is the union of its four edges and the boundary of a 3-cell is the union of its six faces. For practical purposes it is easy to use neighborhood operations (called local operations) on a digital image I which de_ne a value at p 2 C in the transformed image based on pixelvalues in I at p 2 C and its immediate neighbors in N_(p).2 Non-iterative AlgorithmsNon-iterative algorithms deliver subsets of components in specied scan orders without testing connectivity preservation in a number of iterations. In this section we only use the grid point model.2.1 \Distance Skeleton" AlgorithmsBlum [3] suggested a skeleton representation by a set of symmetric points.In a closed subset of the Euclidean plane a point p is called symmetric i_ at least 2 points exist on the boundary with equal distances to p. For every symmetric point, the associated maximal disc is the largest disc in this set. The set of symmetric points, each labeled with the radius of the associated maximal disc, constitutes the skeleton of the set. This idea of presenting a component of a digital image as a \distance skeleton" is based on the calculation of a speci_ed distance from each point in a connected subset M _ C to the complement of the subset. The local maxima of the subset represent a \distance skeleton". In [15] the d4-distance is specied as follows. De_nition 1 The distance d4(p; q) from point p to point q, p 6= q, is the smallest positive integer n such that there exists a sequence of distinct grid points p = p0,p1; p2; :::; pn = q with pi is a 4-neighbor of pi 1, 1 _ i _ n. If p = q the distance between them is de_ned to be zero. The distance d4(p; q) has all properties of a metric. Given a binary digital image. We transform this image into a new one which represents at each point p 2 hIi the d4-distance to pixels having value zero. The transformation includes two steps. We apply functions f1 to the image I in standard scan order, producing I_(i; j) = f1(i; j; I(i; j)), and f2 in reverse standard scan order, producing T(i; j) = f2(i; j; I_(i; j)), as follows:f1(i; j; I(i; j)) =8><>>:0 if I(i; j) = 0minfI_(i 1; j)+ 1; I_(i; j 1) + 1gif I(i; j) = 1 and i 6= 1 or j 6= 1m+ n otherwisef2(i; j; I_(i; j)) = minfI_(i; j); T(i+ 1; j)+ 1; T(i; j + 1) + 1gThe resulting image T is the distance transform image of I. Note that T is a set f[(i; j); T(i; j)] : 1 _ i _ n ^ 1 _ j _ mg, and let T_ _ T such that [(i; j); T(i; j)] 2 T_ i_ none of the four points in A4((i; j)) has a value in T equal to T(i; j)+1. For all remaining points (i; j) let T_(i; j) = 0. This image T_ is called distance skeleton. Now we apply functions g1 to the distance skeleton T_ in standard scan order, producing T__(i; j) = g1(i; j; T_(i; j)), and g2 to the result of g1 in reverse standard scan order, producing T___(i; j) = g2(i; j; T__(i; j)), as follows:g1(i; j; T_(i; j)) = maxfT_(i; j); T__(i 1; j) 1; T__(i; j 1) 1gg2(i; j; T__(i; j)) = maxfT__(i; j); T___(i + 1; j) 1; T___(i; j + 1) 1gThe result T___ is equal to the distance transform image T. Both functions g1 and g2 de_ne an operator G, with G(T_) = g2(g1(T_)) = T___, and we have [15]: Theorem 1 G(T_) = T, and if T0 is any subset of image T (extended to an image by having value 0 in all remaining positions) such that G(T0) = T, then T0(i; j) = T_(i; j) at all positions of T_ with non-zero values. Informally, the theorem says that the distance transform image is reconstructible from the distance skeleton, and it is the smallest data set needed for such a reconstruction. The used distance d4 di_ers from the Euclidean metric. For instance, this d4-distance skeleton is not invariant under rotation. For an approximation of the Euclidean distance, some authors suggested the use of di_erent weights for grid point neighborhoods [4]. Montanari [11] introduced a quasi-Euclidean distance. In general, the d4-distance skeleton is a subset of pixels (p; T(p)) of the transformed image, and it is not necessarily connected.2.2 \Critical Points" AlgorithmsThe simplest category of these algorithms determines the midpoints of subsets of connected components in standard scan order for each row. Let l be an index for the number of connected components in one row of the original image. We de_ne the following functions for 1 _ i _ n: ei(l) = _ j if this is the lth case I(i; j) = 1 ^ I(i; j 1) = 0 in row i, counting from the left, with I(i; 1) = 0 ，oi(l) = _ j if this is the lth case I(i; j) = 1^ I(i; j+ 1) = 0 ，in row i, counting from the left, with I(i;m+ 1) = 0 ，mi(l) = int((oi(l) ei(l)=2)+ oi(l) ，The result of scanning row i is a set of coordinates (i;mi(l)) of midpoints ，of the connected components in row i. The set of midpoints of all rows constitutes a critical point skeleton of an image I. This method is computationally eÆcient.The results are subsets of pixels of the original objects, and these subsets are not necessarily connected. They can form \noisy branches" when object components are nearly parallel to image rows. They may be useful for special applications where the scanning direction is approximately perpendicular to main orientations of object components.References[1] C. Arcelli, L. Cordella, S. Levialdi: Parallel thinning of binary pictures. Electron. Lett. 11:148{149, 1975}.[2] C. Arcelli, G. Sanniti di Baja: Skeletons of planar patterns. in: Topolog- ical Algorithms for Digital Image Processing (T. Y. Kong, A. Rosenfeld, eds.), North-Holland, 99{143, 1996.}[3] H. Blum: A transformation for extracting new descriptors of shape. in: Models for the Perception of Speech and Visual Form (W. Wathen- Dunn, ed.), MIT Press, Cambridge, Mass., 362{380, 1967.19}数字图像处理1引言许多研究者已提议提出了在数字图像里的连接组件是由一个减少的数据量或简化的形状。

Digital Image Processing and Edge DetectionDigital Image ProcessingInterest in digital image processing methods stems from two principal applica- tion areas: improvement of pictorial information for human interpretation; and processing of image data for storage, transmission, and representation for au- tonomous machine perception.An image may be defined as a two-dimensional function, f(x, y), where x and y are spatial (plane) coordinates, and the amplitude of f at any pair of coordinates (x, y) is called the intensity or gray level of the image at that point. When x, y, and the amplitude values of f are all finite, discrete quantities, we call the image a digital image. The field of digital image processing refers to processing digital images by means of a digital computer. Note that a digital image is composed of a finite number of elements, each of which has a particular location and value. These elements are referred to as picture elements, image elements, pels, and pixels. Pixel is the term most widely used to denote the elements of a digital image.Vision is the most advanced of our senses, so it is not surprising that images play the single most important role in human perception. However, unlike humans, who are limited to the visual band of the electromagnetic (EM) spec- trum, imaging machines cover almost the entire EM spectrum, ranging from gamma to radio waves. They can operate on images generated by sources that humans are not accustomed to associating with images. These include ultra- sound, electron microscopy, and computer-generated images. Thus, digital image processing encompasses a wide and varied field of applications.There is no general agreement among authors regarding where image processing stops and other related areas, such as image analysis and computer vi- sion, start. Sometimes a distinction is made by defining image processing as a discipline in which both the input and output of a process are images. We believe this to be a limiting and somewhat artificial boundary. For example, under this definition, even the trivial task of computing the average intensity of an image (which yields a single number)would not be considered an image processing operation. On the other hand, there are fields such as computer vision whose ultimate goal is to use computers to emulate human vision, including learning and being able to make inferences and take actions based on visual inputs. This area itself is a branch of artificial intelligence (AI) whose objective is to emulate human intelligence. The field of AI is in its earliest stages of infancy in terms of development, with progress having been much slower than originally anticipated. The area of image analysis (also called image understanding) is in be- tween image processing and computer vision.There are no clearcut boundaries in the continuum from image processing at one end to computer vision at the other. However, one useful paradigm is to consider three types of computerized processes in this continuum: low-, mid-, and highlevel processes. Low-level processes involve primitive opera- tions such as image preprocessing to reduce noise, contrast enhancement, and image sharpening. A low-level process is characterized by the fact that both its inputs and outputs are images. Mid-level processing on images involves tasks such as segmentation (partitioning an image into regions or objects), description of those objects to reduce them to a form suitable for computer processing, and classification (recognition) of individual objects. A midlevel process is characterized by the fact that its inputs generally are images, but its outputs are attributes extracted from those images (e.g., edges, contours, and the identity of individual objects). Finally, higherlevel processing involves “making sense” of an ensemble of recognized objects, as in image analysis, and, at the far end of the continuum, performing the cognitive functions normally associated with vision.Based on the preceding comments, we see that a logical place of overlap between image processing and image analysis is the area of recognition of individual regions or objects in an image. Thus, what we call in this book digital image processing encompasses processes whose inputs and outputs are images and, in addition, encompasses processes that extract attributes from images, up to and including the recognition of individual objects. As a simple illustration to clarify these concepts,consider the area of automated analysis of text. The processes of acquiring an image of the area containing the text, preprocessing that image, extracting (segmenting) the individual characters, describing the characters in a form suitable for computer processing, and recognizing those individual characters are in the scope of what we call digital image processing in this book. Making sense of the content of the page may be viewed as being in the domain of image analysis and even computer vision, depending on the level of complexity implied by the statement “making sense.” As will become evident shortly, digital image processing, as we have defined it, is used successfully in a broad range of areas of exceptional social and economic value.The areas of application of digital image processing are so varied that some form of organization is desirable in attempting to capture the breadth of this field. One of the simplest ways to develop a basic understanding of the extent of image processing applications is to categorize images according to their source (e.g., visual, X-ray, and so on). The principal energy source for images in use today is the electromagnetic energy spectrum. Other important sources of energy include acoustic, ultrasonic, and electronic (in the form of electron beams used in electron microscopy). Synthetic images, used for modeling and visualization, are generated by computer. In this section we discuss briefly how images are generated in these various categories and the areas in which they are applied.Images based on radiation from the EM spectrum are the most familiar, es- pecially images in the X-ray and visual bands of the spectrum. Electromagnet- ic waves can be conceptualized as propagating sinusoidal waves of varying wavelengths, or they can be thought of as a stream of massless particles, each traveling in a wavelike pattern and moving at the speed of light. Each massless particle contains a certain amount (or bundle) of energy. Each bundle of energy is called a photon. If spectral bands are grouped according to energy per photon, we obtain the spectrum shown in fig. below, ranging from gamma rays (highest energy) at one end to radio waves (lowest energy) at the other. The bands are shown shaded to convey the fact that bands of the EM spectrum are not distinct but rather transition smoothly from one to the other.Image acquisition is the first process. Note that acquisition could be as simple as being given an image that is already in digital form. Generally, the image acquisition stage involves preprocessing, such as scaling.Image enhancement is among the simplest and most appealing areas of digital image processing. Basically, the idea behind enhancement techniques is to bring out detail that is obscured, or simply to highlight certain features of interest in an image. A familiar example of enhancement is when we increase the contr ast of an image because “it looks better.” It is important to keep in mind that enhancement is a very subjective area of image processing. Image restoration is an area that also deals with improving the appearance of an image. However, unlike enhancement, which is subjective, image restoration is objective, in the sense that restoration techniques tend to be based on mathematical or probabilistic models of image degradation. Enhancement, on the other hand, is based on human subjective preferences regarding what constitutes a “good” enhancement result.Color image processing is an area that has been gaining in importance because of the significant increase in the use of digital images over the Internet. It covers a number of fundamental concepts in color models and basic color processing in a digital domain. Color is used also in later chapters as the basis for extracting features of interest in an image.Wavelets are the foundation for representing images in various degrees of resolution. In particular, this material is used in this book for image data compression and for pyramidal representation, in which images are subdivided successively into smaller regions.Compression, as the name implies, deals with techniques for reducing the storage required to save an image, or the bandwidth required to transmi it.Although storage technology has improved significantly over the past decade, the same cannot be said for transmission capacity. This is true particularly in uses of the Internet, which are characterized by significant pictorial content. Image compression is familiar (perhaps inadvertently) to most users of computers in the form of image file extensions, such as the jpg file extension used in the JPEG (Joint Photographic Experts Group) image compression standard.Morphological processing deals with tools for extracting image components that are useful in the representation and description of shape. The material in this chapter begins a transition from processes that output images to processes that output image attributes.Segmentation procedures partition an image into its constituent parts or objects.In general, autonomous segmentation is one of the most difficult tasks in digital imageprocessing. A rugged segmentation procedure brings the process a long way toward successful solution of imaging problems that require objects to be identified individually. On the other hand, weak or erratic segmentation algorithms almost always guarantee eventual failure. In general, the more accurate the segmentation, the more likely recognition is to succeed.Representation and description almost always follow the output of a segmentation stage, which usually is raw pixel data, constituting either the bound- ary of a region (i.e., the set of pixels separating one image region from another) or all the points in the region itself. In either case, converting the data to a form suitable for computer processing is necessary. The first decision that must be made is whether the data should be represented as a boundary or as a complete region. Boundary representation is appropriate when the focus is on external shape characteristics, such as corners and inflections. Regional representation is appropriate when the focus is on internal properties, such as texture or skeletal shape. In some applications, these representations complement each other. Choosing a representation is only part of the solution for trans- forming raw data into a form suitable for subsequent computer processing. A method must also be specified for describing the data so that features of interest are highlighted. Description, also called feature selection, deals with extracting attributes that result in some quantitative information of interest or are basic for differentiating one class of objects from another.Recognition is the process that assigns a label (e.g., “vehicle”) to an object based on its descriptors. As detailed before, we conclude our coverage of digital image processing with the development of methods for recognition of individual objects.So far we have said nothing about the need for prior knowledge or about the interaction between the knowledge base and the processing modules in Fig2 above. Knowledge about a problem domain is coded into an image processing system in the form of a knowledge database. This knowledge may be as sim- ple as detailing regions of an image where the information of interest is known to be located, thus limiting the search that has to be conducted in seeking that information. The knowledge base alsocan be quite complex, such as an interrelated list of all major possible defects in a materials inspection problem or an image database containing high-resolution satellite images of a region in con- nection with change-detection applications. In addition to guiding the operation of each processing module, the knowledge base also controls the interaction between modules. This distinction is made in Fig2 above by the use of double-headed arrows between the processing modules and the knowledge base, as op- posed to single-headed arrows linking the processing modules.Edge detectionEdge detection is a terminology in image processing and computer vision, particularly in the areas of feature detection and feature extraction, to refer to algorithms which aim at identifying points in a digital image at which the image brightness changes sharply or more formally has discontinuities.Although point and line detection certainly are important in any discussion on segmentation,edge dectection is by far the most common approach for detecting meaningful discounties in gray level.Although certain literature has considered the detection of ideal step edges, the edges obtained from natural images are usually not at all ideal step edges. Instead they are normally affected by one or several of the following effects:1.focal blur caused by a finite depth-of-field and finite point spread function; 2.penumbral blur caused by shadows created by light sources of non-zero radius; 3.shading at a smooth object edge; 4.local specularities or interreflections in the vicinity of object edges.A typical edge might for instance be the border between a block of red color and a block of yellow. In contrast a line (as can be extracted by a ridge detector) can be a small number of pixels of a different color on an otherwise unchanging background. For a line, there may therefore usually be one edge on each side of the line.To illustrate why edge detection is not a trivial task, let us consider the problem of detecting edges in the following one-dimensional signal. Here, we may intuitively say that there should be an edge between the 4th and 5th pixels.If if the intensity differences between the adjacent neighbouring pixels were higher, it would not be as easy to say that there should be an edge in the corresponding region. Moreover, one could argue that this case is one in which there are several edges.Hence, to firmly state a specific threshold on how large the intensity change between two neighbouring pixels must be for us to say that there should be an edge between these pixels is not always a simple problem. Indeed, this is one of the reasons why edge detection may be a non-trivial problem unless the objects in the scene are particularly simple and the illumination conditions can be well controlled.There are many methods for edge detection, but most of them can be grouped into two categories,search-based and zero-crossing based. The search-based methods detect edges by first computing a measure of edge strength, usually a first-order derivative expression such as the gradient magnitude, and then searching for local directional maxima of the gradient magnitude using a computed estimate of the local orientation of the edge, usually the gradient direction. The zero-crossing based methods search for zero crossings in a second-order derivative expression computed from the image in order to find edges, usually the zero-crossings of the Laplacian or the zero-crossings of a non-linear differential expression, as will be described in the section on differential edge detection following below. As a pre-processing step to edge detection, a smoothing stage, typically Gaussian smoothing, is almost always applied (see also noise reduction).The edge detection methods that have been published mainly differ in the types of smoothing filters that are applied and the way the measures of edge strength are computed. As many edge detection methods rely on the computation of image gradients, they also differ in the types of filters used for computing gradient estimates in the x- and y-directions.Once we have computed a measure of edge strength (typically the gradient magnitude), the next stage is to apply a threshold, to decide whether edges are present or not at an image point. The lower the threshold, the more edges will be detected, and the result will be increasingly susceptible to noise, and also to picking out irrelevant features from the image.Conversely a high threshold may miss subtle edges, or result in fragmented edges.If the edge thresholding is applied to just the gradient magnitude image, the resulting edges will in general be thick and some type of edge thinning post-processing is necessary. For edges detected with non-maximum suppression however, the edge curves are thin by definition and the edge pixels can be linked into edge polygon by an edge linking (edge tracking) procedure. On a discrete grid, the non-maximum suppression stage can be implemented by estimating the gradient direction using first-order derivatives, then rounding off the gradient direction to multiples of 45 degrees, and finally comparing the values of the gradient magnitude in the estimated gradient direction.A commonly used approach to handle the problem of appropriate thresholds for thresholding is by using thresholding with hysteresis. This method uses multiple thresholds to find edges. We begin by using the upper threshold to find the start of an edge. Once we have a start point, we then trace the path of the edge through the image pixel by pixel, marking an edge whenever we are above the lower threshold. We stop marking our edge only when the value falls below our lower threshold. This approach makes the assumption that edges are likely to be in continuous curves, and allows us to follow a faint section of an edge we have previously seen, without meaning that every noisy pixel in the image is marked down as an edge. Still, however, we have the problem of choosing appropriate thresholding parameters, and suitable thresholding values may vary over the image.Some edge-detection operators are instead based upon second-order derivatives of the intensity. This essentially captures the rate of change in the intensity gradient. Thus, in the ideal continuous case, detection of zero-crossings in the second derivative captures local maxima in the gradient.We can come to a conclusion that,to be classified as a meaningful edge point,the transition in gray level associated with that point has to be significantly stronger than the background at that point.Since we are dealing with local computations,the method of choice to determine whether a value is “significant” or not id to use a threshold.Thus we define a point in an image as being as being an edge point if its two-dimensional first-order derivative is greater than a specified criterion of connectedness is by definition an edge.The term edgesegment generally is used if the edge is short in relation to the dimensions of the image.A key problem in segmentation is to assemble edge segments into longer edges.An alternate definition if we elect to use the second-derivative is simply to define the edge ponits in an image as the zero crossings of its second derivative.The definition of an edge in this case is the same as above.It is important to note that these definitions do not guarantee success in finding edge in an image.They simply give us a formalism to look for them.First-order derivatives in an image are computed using the gradient.Second-order derivatives are obtained using the Laplacian.数字图像处理与边缘检测数字图像处理数字图像处理方法的研究源于两个主要应用领域：其一是为了便于人们分析而对图像信息进行改进：其二是为使机器自动理解而对图像数据进行存储、传输及显示。

第 1 页中英文对照资料外文翻译文献原 文To image edge examination algorithm researchAbstract ：Digital image processing took a relative quite young discipline,is following the computer technology rapid development, day by day obtains th widespread application.The edge took the image one kind of basic characteristic,in the pattern recognition, the image division, the image intensification as well as the image compression and so on in the domain has a more widesp application.Image edge detection method many and varied, in which based on brightness algorithm, is studies the time to be most long, the theory develo the maturest method, it mainly is through some difference operator, calculates its gradient based on image brightness the change, thus examines the edge, mainlyhas Robert, Laplacian, Sobel, Canny, operators and so on LOG 。

引言英文文献原文Digital image processing and pattern recognition techniques for the detection of cancerCancer is the second leading cause of death for both men and women in the world , and is expected to become the leading cause of death in the next few decades . In recent years , cancer detection has become a significant area of research activities in the image processing and pattern recognition community .Medical imaging technologies have already made a great impact on our capabilities of detecting cancer early and diagnosing the disease more accurately . In order to further improve the efficiency and veracity of diagnoses and treatment , image processing and pattern recognition techniques have been widely applied to analysis and recognition of cancer , evaluation of the effectiveness of treatment , and prediction of the development of cancer . The aim of this special issue is to bring together researchers working on image processing and pattern recognition techniques for the detection and assessment of cancer , and to promote research in image processing and pattern recognition for oncology . A number of papers were submitted to this special issue and each was peer-reviewed by at least three experts in the field . From these submitted papers , 17were finally selected for inclusion in this special issue . These selected papers cover a broad range of topics that are representative of the state-of-the-art in computer-aided detection or diagnosis(CAD)of cancer . They cover several imaging modalities(such as CT , MRI , and mammography) and different types of cancer (including breast cancer , skin cancer , etc.) , which we summarize below .Skin cancer is the most prevalent among all types of cancers . Three papers in this special issue deal with skin cancer . Y uan et al. propose a skin lesion segmentation method. The method is based on region fusion and narrow-band energy graph partitioning . The method can deal with challenging situations with skin lesions , such as topological changes , weak or false edges , and asymmetry . T ang proposes a snake-based approach using multi-direction gradient vector flow (GVF) for the segmentation of skin cancer images . A new anisotropic diffusion filter is developed as a preprocessing step . After the noise is removed , the image is segmented using a GVF1snake . The proposed method is robust to noise and can correctly trace the boundary of the skin cancer even if there are other objects near the skin cancer region . Serrano et al. present a method based on Markov random fields (MRF) to detect different patterns in dermoscopic images . Different from previous approaches on automatic dermatological image classification with the ABCD rule (Asymmetry , Border irregularity , Color variegation , and Diameter greater than 6mm or growing) , this paper follows a new trend to look for specific patterns in lesions which could lead physicians to a clinical assessment.Breast cancer is the most frequently diagnosed cancer other than skin cancer and a leading cause of cancer deaths in women in developed countries . In recent years , CAD schemes have been developed as a potentially efficacious solution to improving radiologists’diagnostic accuracy in breast cancer screening and diagnosis . The predominant approach of CAD in breast cancer and medical imaging in general is to use automated image analysis to serve as a “second reader”, with the aim of improving radiologists’diagnostic performance . Thanks to intense research and development efforts , CAD schemes have now been introduces in screening mammography , and clinical studies have shown that such schemes can result in higher sensitivity at the cost of a small increase in recall rate . In this issue , we have three papers in the area of CAD for breast cancer . Wei et al. propose an image-retrieval based approach to CAD , in which retrieved images similar to that being evaluated (called the query image) are used to support a CAD classifier , yielding an improved measure of malignancy . This involves searching a large database for the images that are most similar to the query image , based on features that are automatically extracted from the images . Dominguez et al. investigate the use of image features characterizing the boundary contours of mass lesions in mammograms for classification of benign vs. Malignant masses . They study and evaluate the impact of these features on diagnostic accuracy with several different classifier designs when the lesion contours are extracted using two different automatic segmentation techniques . Schaefer et al. study the use of thermal imaging for breast cancer detection . In their scheme , statistical features are extracted from thermograms to quantify bilateral differences between left and right breast regions , which are used subsequently as input to a fuzzy-rule-based classification system for diagnosis.Colon cancer is the third most common cancer in men and women , and also the third mostcommon cause of cancer-related death in the USA . Y ao et al. propose a novel technique to detect colonic polyps using CT Colonography . They use ideas from geographic information systems to employ topographical height maps , which mimic the procedure used by radiologists for the detection of polyps . The technique can also be used to measure consistently the size of polyps . Hafner et al. present a technique to classify and assess colonic polyps , which are precursors of colorectal cancer . The classification is performed based on the pit-pattern in zoom-endoscopy images . They propose a novel color waveler cross co-occurence matrix which employs the wavelet transform to extract texture features from color channels.Lung cancer occurs most commonly between the ages of 45 and 70 years , and has one of the worse survival rates of all the types of cancer . Two papers are included in this special issue on lung cancer research . Pattichis et al. evaluate new mathematical models that are based on statistics , logic functions , and several statistical classifiers to analyze reader performance in grading chest radiographs for pneumoconiosis . The technique can be potentially applied to the detection of nodules related to early stages of lung cancer . El-Baz et al. focus on the early diagnosis of pulmonary nodules that may lead to lung cancer . Their methods monitor the development of lung nodules in successive low-dose chest CT scans . They propose a new two-step registration method to align globally and locally two detected nodules . Experments on a relatively large data set demonstrate that the proposed registration method contributes to precise identification and diagnosis of nodule development .It is estimated that almost a quarter of a million people in the USA are living with kidney cancer and that the number increases by 51000 every year . Linguraru et al. propose a computer-assisted radiology tool to assess renal tumors in contrast-enhanced CT for the management of tumor diagnosis and response to treatment . The tool accurately segments , measures , and characterizes renal tumors, and has been adopted in clinical practice . V alidation against manual tools shows high correlation .Neuroblastoma is a cancer of the sympathetic nervous system and one of the most malignant diseases affecting children . Two papers in this field are included in this special issue . Sertel et al. present techniques for classification of the degree of Schwannian stromal development as either stroma-rich or stroma-poor , which is a critical decision factor affecting theprognosis . The classification is based on texture features extracted using co-occurrence statistics and local binary patterns . Their work is useful in helping pathologists in the decision-making process . Kong et al. propose image processing and pattern recognition techniques to classify the grade of neuroblastic differentiation on whole-slide histology images . The presented technique is promising to facilitate grading of whole-slide images of neuroblastoma biopsies with high throughput .This special issue also includes papers which are not derectly focused on the detection or diagnosis of a specific type of cancer but deal with the development of techniques applicable to cancer detection . T a et al. propose a framework of graph-based tools for the segmentation of microscopic cellular images . Based on the framework , automatic or interactive segmentation schemes are developed for color cytological and histological images . T osun et al. propose an object-oriented segmentation algorithm for biopsy images for the detection of cancer . The proposed algorithm uses a homogeneity measure based on the distribution of the objects to characterize tissue components . Colon biopsy images were used to verify the effectiveness of the method ; the segmentation accuracy was improved as compared to its pixel-based counterpart . Narasimha et al. present a machine-learning tool for automatic texton-based joint classification and segmentation of mitochondria in MNT-1 cells imaged using an ion-abrasion scanning electron microscope . The proposed approach has minimal user intervention and can achieve high classification accuracy . El Naqa et al. investigate intensity-volume histogram metrics as well as shape and texture features extracted from PET images to predict a patient’s response to treatment . Preliminary results suggest that the proposed approach could potentially provide better tools and discriminant power for functional imaging in clinical prognosis.We hope that the collection of the selected papers in this special issue will serve as a basis for inspiring further rigorous research in CAD of various types of cancer . We invite you to explore this special issue and benefit from these papers .On behalf of the Editorial Committee , we take this opportunity to gratefully acknowledge the autors and the reviewers for their diligence in abilding by the editorial timeline . Our thanks also go to the Editors-in-Chief of Pattern Recognition , Dr. Robert S. Ledley and Dr.C.Y. Suen , for their encouragement and support for this special issue .英文文献译文数字图像处理和模式识别技术关于检测癌症的应用世界上癌症是对于人类（不论男人还是女人）生命的第二杀手。

人工智能在癌症治疗中的应用教程引言：癌症作为一种生命威胁严重的疾病，是世界范围内的头号杀手之一。

不仅对患者及其家庭带来了心理和经济的压力，而且对于整个医疗系统来说也是一个重大挑战。

然而，随着科技的迅速发展，人工智能（AI）在医疗领域的应用日益增加，为癌症治疗带来了革命性的改变。

本文将介绍人工智能在癌症治疗中的应用，以及相关技术、工具和资源，希望能够为医疗专业人士和患者提供有价值的信息。

一、人工智能在癌症诊断中的应用1. 图像识别技术图像识别技术是人工智能在癌症诊断中广泛应用的一种技术。

通过对病例的影像数据进行深度学习，可以帮助医生快速准确地诊断癌症。

例如，通过对乳腺X 光片进行分析，AI可以检测出可能存在的肿瘤，并进一步指导医生进行进一步的检测和治疗。

此外，在肿瘤组织的病理学诊断中，AI也发挥了重要作用。

传统的病理学诊断需要经验丰富的医生对组织切片进行观察和判断，而AI可以通过分析大量的组织图像，以更准确的方式判断细胞的恶性程度，从而提供更准确的诊断结果。

2. 基因组学分析基因组学分析是应用人工智能进行癌症诊断和治疗的另一个重要领域。

通过对大规模基因组学数据的分析，AI可以识别出癌症相关基因的突变和变异。

这对于理解癌症的发生机制以及开发个性化治疗方案非常重要。

基因组学分析还可以帮助识别患者对某些药物的反应情况。

在个体化治疗中，医生可以根据基因组学分析结果，选择更合适的药物来针对患者的特殊基因型和突变情况，从而提高治疗效果。

二、人工智能在癌症治疗中的应用1. 个体化治疗人工智能在个体化治疗中扮演着重要角色。

通过分析患者的基因组学数据、遗传信息、病理学特征等多种数据，并结合临床经验和医学指南，AI可以帮助医生制定更精准的治疗方案。

个体化治疗不仅可以提供更高效的治疗效果，而且可以减少不必要的治疗和药物的副作用。

2. 预后评估提前预测患者的癌症发展趋势和预后是非常重要的。

通过机器学习和深度学习技术，AI可以对丰富的临床和生物信息进行整合和分析，以提供准确的预后评估结果。