1-金刚烷甲酸828-51-3

些溶剂的介电常数介电常数(Dielectric constants)表1列出常见气体在20°C, 101 325 Pa条件下的介电常识（£ ）。

数据中的有效数字表示测试精度，其中Ar, H2, He , N 2, O2, CO2等被推荐为参比数据，其精度为百万分之一或更高。

1气体的介电常数(D feJectric constants ofgases )表1 气体的介电常数Tabb 1 D ielectrr constants ofgases化学式C hem ralfom ula 名称D enom nationEAr（不含碳物质）空气（干基，无C0 2）氮1.00053641.0005172BF3 三氟化硼 1.0011 HBr 澳化氢 1.00279 HC1 氯化氢 1.00390 HI 碘化氢 1.00214 H 2 氢 1.0002538 H2S 硫化氢 1.00344 He M 1.0000650 Kr 氮 1.00078 NFs 三氟化氮 1.0013 NH 3 氨 1.00622 NO 一氧化氮 1.00060 N 2 氮 1.0005480 N 2O 一氧化二氮 1.00104 Ne M 1.00013 O2 氧 1.0004947 Os 臭氧 1.0017 SFe 六氟化硫 1.00200 SO2 二氧化硫 1.00825 XE 1.00126CF4 （含碳物质）四氟甲烷 1.00121CO 一氧化碳 1.00262 CO2 二氧化碳 1.000922CH sBr 澳代甲烷 1.01028 CH sCl 氯代甲烷 1.01080CH F氟代甲烷 1.00973 3CHs I 碘代甲烷 1.00914CH4 甲烷 1.00081C2H 2 乙烘 1.00124C2H3CI 氯乙烯 1.0075C2H 4 乙烯 1.00134C2H5C1 氯乙烷 1.01325C2H 6 乙烷 1.00140C2H 60 甲醛 1.0062CsH 6 丙烯 1.00228CsH 6 环丙烷 1.00178CsH 6 丙烷 1.00200C 4 H 10 丁烷 1.00258C 4 H 10 异丁烷 1.00260 2饱和水蒸气的介电常数(D ielectric constants of saturated watervapor ) 表2给出不同温度下的液态水成平衡的水蒸气的介电常数。

沙格列汀杂质列表序号中文名称英文名称CAS 结构式1（S)-焦谷氨酸乙酯Saxaint-A NO2（S)-1-Boc-焦谷氨酸乙酯Saxaint-B NO 3(S)-1-Boc-2,3-二氢吡咯-２-甲酸乙酯Saxaint-C NO4(1S,3S,5S)-2-Boc-2-氮杂-双环[3.1.0]己基-3-甲酸乙酯Saxaint-D NO 5(1S,3S,5S)-2-Boc-2-氮杂-双环[3.1.0]己基-3-甲酰胺盐酸盐Saxaint-E NO6N-Boc-3-羟基-1-金刚烷基-甘氨酸Saxaint-F no7(s)-N-叔丁氧羰基-3-羟基-1-金刚烷基-甘氨酸Saxaint-G no(s)-3-羟基-1-金刚烷基-甘氨酸Saxaint-H NO9N-Boc-3-羟基-1-金刚烷基-甘氨酸Saxaint-I 361442-00-410N-Boc-沙克列汀Saxaint-J NO111-金刚烷甲酸Saxaint-K 828-51-3121-金刚烷甲酰氯Saxaint-L 218-252-7132-（1-金刚烷甲酰基）丙二酸乙酯Saxaint-M NO141-乙酰金刚烷Saxaint-N 39917-38-9153-羟基-1-草酰金刚烷Saxaint-O NO沙格列汀Saxagliptin 361442-04-817沙格列汀杂质Epimer-A S,S,S,R (SG-D2)18沙格列汀杂质Epimer-B S,R,S,S(SG-D5)19沙格列汀杂质Enantiomer-C R,R,R,R(SG-E)20沙格列汀杂质Distereomer-DR,R,S,S(SG-D4)21沙格列汀杂质Distereomer-ER,S,R,R(SG-D6)22沙格列汀杂质Distereomer-FR,S,R,R(SG-D6)23沙格列汀杂质Distereomer-GS,R,R,R(SG-D1)24沙格列汀杂质SaxagliptinImpurity SG-8沙格列汀杂质SaxagliptinImpurity SG-926沙格列汀杂质Saxagliptin ImpuritySG-1027沙格列汀杂质SaxagliptinImpurity SG-H28沙格列汀杂质SaxagliptinImpurity SG-I29沙格列汀杂质SaxagliptinImpurity SG-G30沙格列汀杂质SaxagliptinImpurity SG-K31沙格列汀杂质SaxagliptinImpurity SG-L32沙格列汀杂质SaxagliptinImpurity SG-M沙格列汀杂质SaxagliptinImpurity SG-N34沙格列汀杂质SaxagliptinImpurity SG-O35沙格列汀杂质Saxagliptin Impurity36沙格列汀杂质SaxagliptinImpurity M137沙格列汀杂质SaxagliptinImpurity M2。

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ETHOXIDE4,5-DICHLORO-3H-1,2-DITHIOL-3-ONE4,5-DICHLORO-3H-1,2-DITHIOL-3-ONE /NDFEB MAGNETIC POWDER TRIPROPYLENE GLYCOL DIACRYLATE(TPGDA）ORGANIC PEROXIDE TYPE E,LIQUID(DI-TERT-AMYL PEROXIDE)TMAH(25%TETRA METHYL AMMONIUM HYDROXIDE)TRIHEXYLALUMINUM SOLUTION (50-70%)DIETHYLALUMINIUMMONOISOPROPYLAMINEFORMIC ACID WITH MORE THAN 85% ACID,BY MASS FORMIC ACID 90 PERCENTUNIPOL(TM)UCAT(TM)J-1 P25 CATALYSTCALCIUM DODECYL BENZENE SULFONATE ISOBUTANOL SOLVENTPARAQUAT DICHLORIDE 20% IONINDUSTRIAL BARIUM CHLORIDE2，4-DINITRO-6-SEC-BUTYLPHENOL 70% SOLUTION INETHYLBENZENEDIBUTYLTIN DILAURATEZIRCONYL CHLORIDEBARIUM CHLORIDEBIS(4-METHYLBENZOYL)PEROXIDE1，2-(METHYLENEDIOXY)BENZENESILICONE POLYMER TOPCOATCURING AGENTPAINT RELATED MATERIAL（THINNER)PAINT （EPOXY MICACEOUS IRON)PAINT （EPOXY ZINC PHOSPHATE SEALING PAINT)PAINT （EPOXY ZINC RICH PRIMER)2-METHYLNAPHTHALENENEODECANOIC ACID VINYL ESTER(SHIVENA 10)NITROGEN TRIFLUORIDE（NF3)POLYTRAK CATALYST/POLYPROPYLENE CATALYSTMETHANESULFONYL CHLORIDECALCIUM ALUMINUM ALLOYNOT MARINE POLLUTANT1，1-DI(TERT-AMYLPEROXY)CYCLOHEXANEVULKANOX 4-ADPAORGANIC PEROXIDE TYPE C, LIQUID（2,5-BISTERT-BUTYL PEROXY-2，5-DIMETHYLHEXANE)PIVALOYL CHLORIDESODIUM PERCARBONATE/SODIUM PERCARBONATE COATEDABAMECTIN ECYTTRIUM(III)/CALCIUM(II)SULFAMATESYNTHETIC PRIMER TYPE BTHIOUREAREFINED NAPHTHALENE2，5-DIMETHYL-2，5-DI(TERT-BUTYLPEROXY)HEXANECLETHODIM 37%TWO-COMPONENT ROADMARKING PAINTSILICIDE CALCIUM-STEEL-MAKING ADDITIVELITHIUM ION BATTERY PACK/BATTERY PACK,4 CELL 25-97-180 MR(180 DEG C CELLS)TEOF(TRIMETHYL ORTHOFORMATE)CYANOACETIC ACID POTASSIUM MONOPERSULFATE COMPOUNDBETA NAPHTOLCHROMIC ACIDPLASTIC PIPE ADHESIVEUNSATURATED POLYESTER RESIN FLCRYSTALLINE TEDACALCIUM SILICON POWDER SODIUM DICHLOROISOCYANURATE DIHYDRATE ACCLAIM™ K-120 CATALYSTPERCHLORIC ACIDO-ANISIDINE(ORTHO-ANISIDINE)ETHYLENE BRASSYLATE(MUSK-T)GEL FUEL(ETHANOL)CORANOLCOUMARINMUSK YINGHAI 50% IN BBPARTA INTERLINE 859 PARTATRISODIUM PHOSPHATEPEROXYACETIC ACIDBENZYL SALICYLATE 99% MIN2，4-DIMETHYLANILINEMETHANE SULFONIC ACID,70%CAUSTIC SODA FLAKESLIQUID HELIUMMT 2110 CATALYSTLANASYN BLACK M-DL P120BATTERY FLUID, ACIDACRYLIC POLYOL RESINPHOSPHINELAMBDA-CYHALOTHRIN ECLEAD NITRATE SOLUTION 24%TINO CATALYST IN OILIP SOLVENT 1620MAGNESIUM TURNINGSGF-60MC MATCHING THINNERGF-60MC INTERIOR SUPER-THIN TYPE STEEL STRUCTURE FIRE-PROOF COATINGTRIFLUOROMETHANESULFONIC ANHYDRIDEINDOMETHACIN1,1-DI(TERT-BUTYLPEROXY)CYCLOHEXANESODIUM SELENITEANTIRUST COATING MATERIALACENAPHTHENEPOTASSIUM CYANIDE2-BENZYL-2-(DIMETHYLAMINO)-1-[4-4-MORPHOLINYL)PHENYL]-1-BUTANONENYLOSAN BLUE N-BLN SGRFERRO CALCIUM SILICONN-BUTYL LITHIUMLITHIUM FLUORIDETETRAKIS(HYDROXYMETHYL)PHOSPHONIUM SULPHATE-UREABASIC YELLOW 28 LIQUIDSTRONTIUM METALCLAY CONTROL CLAY TREAT-3CACID CORROSINO INHIBTOR CI-27STABILIZED CHLORINE DIOXIDECORANOLTOXIC SOLID, CORROSIVE, ORGANIC, N.O.S.(N,N-DICYCLOHEXYLCARBODIIMIDE)STYRALLYL ALCOHOLYINGHAITONE1.4-BUTYNEDIOLEMC ELECTROLYTEALLYL HEPTANOATEALLYL HEXANOATELEAD MONOXIDE2，3-DICHLORO-5-(TRIFLUOROMETHYL)PYRIDINEDIFLUBENZURON SCDIETHYL CHLOROTHIOPHOSPHATEHYDROGENATED TALLOWAMINEDODECYL BENZENE SULFONIC ACIDBARIUM SULFIDEINSOLUBLE SULFURIS-OT20TITANNIUM OXYCHLORIDELITHIUM ION CELLNICKEL COMPOUND POWDERCOBALT NITRATECOPPER SULPHATE PENTAHYDRATEEMAMECTIN BENZOATE WDGCALCIUM NITRITEMARINE PAINT2，3-DICHLORO-5-(TRIFLUOROMETHYL)PYRIDINENI-MH BATTERYHEXAMINEZINE SULPHATE HEPTAHYDRATE2-PHOSPHONOBUTANE-1,2,4-TRICARBOXYLICACIDANTISCORCHING AGENT PVIACETIC ACID,GLACIAL MORE THAN 80% ACID,BY MASS GLACIAL ACETIC ACIDFURFURALCOBALT CHLORIDE4-ETHYL-2，3-DIOXO-L-PIPERAZINE CARBONYL CHLORIDEALUMINIUM MAGNESIUM ALLOY POWERPOTASSIUM DICHROMATEALKYD ENAMELLITHIUM HYDROXIDE MONOHYDRATETITANIUM NITRIDETRIETHYLGALLIUMTRIMETHYLALUMINUMTRIMETHYLGALLIUMDIETHYLZINC。

2025届江苏省宜兴市树人中学高一化学第一学期期中质量检测试题请考生注意：1．请用2B 铅笔将选择题答案涂填在答题纸相应位置上，请用0．5毫米及以上黑色字迹的钢笔或签字笔将主观题的答案写在答题纸相应的答题区内。

写在试题卷、草稿纸上均无效。

2．答题前，认真阅读答题纸上的《注意事项》，按规定答题。

一、选择题(共包括22个小题。

每小题均只有一个符合题意的选项）1、氮化铝广泛应用于电子陶瓷等工业领域。

在一定条件下，AlN 可通过以下反应合成：Al 2O 3＋N 2＋3C 2AlN ＋3CO 。

有关该反应下列叙述正确的是A ．上述反应中，N 2是还原剂，Al 2O 3是氧化剂B ．上述反应中，每生成1 mol AlN 需转移3 mol 电子C ．AlN 的摩尔质量为41 gD ．AlN 中氮的化合价为＋32、在同温同压下，A 容器中的氧气(O 2)和B 容器中的氨气(CH 4)所含的原子个数相同，则A 、B 两容器中气体的体积之比是 ( ) A ．5：2B ．2：1C ．2：5D ．3：23、下列说法中不正确的是①NaOH 溶液保存在带橡皮塞的玻璃瓶②重金属盐中毒应立即喝大量的牛奶或者蛋清缓解毒性,并及时送往医院治疗 ③蒸馏时冷凝管进水方式为“下口进冷水，上口出温水”④浓硫酸稀释操作为将水沿烧杯内壁缓缓注入并不断用玻璃棒搅拌 ⑤分液漏斗必须检查旋塞处是否漏水,若不漏水即可使用 ⑥取固体药品一定要用镊子取⑦选择量筒量取液体时,应满足“大而近”的原则,所以应用10mL 的量简量取8.80mL 稀硫酸 ⑧萃取时萃取剂密度不一定大于原溶剂的密度 A ．①②④⑤B ．①③⑤⑥C ．②④⑦⑧D ．④⑤⑥⑦4、关于化学键的下列叙述中，不正确的是（ ） A ．离子化合物可能含共价键 B ．共价化合物一定含共价键 C ．离子化合物中只含离子键D ．共价化合物中不含离子键5、下列物质之间的反应，可以用离子反应方程式23222H CO CO H O +-+→↑+表示的是（ ）A ．3CaCO HCl +B ．23Na CO HCl +C ．23Na CO HAc +D ．33NaHCO HNO +6、铁、稀盐酸、澄清石灰水、氯化铜溶液是初中化学中常见的物质，四种物质间的反应关系如图所示。

常见药物中间体Entecavir恩替卡韦中间体：第1步：3-Cyclopenten-1-ol,2-[(phenylmethoxy)methyl]-,(1R-trans) CAS No:188399-48-6第2步：(1S,2R,3S,5R)-2-(benzyloxymethyl)-6-oxabicyclo[3.1.0]hexan-3-ol CAS No:117641-39-1 第3步：6-Oxabicyclo[3.1.0]hexane,3-(phenylmethoxy)-2-[(phenylmethoxy)methyl]-, (1S,2R,3S,5R) CAS No 110567-22-1第4步：(1S,2S,3S,5S)-5-(2-amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2- (benzyloxymethyl)cyclopentanolcas:142217-77-4第5步：(2R,3S,5S)-3-(benzyloxy)-5-(6-(benzyloxy)-2- ((4-methoxyphenyl)diphenylmethylamino)- 9H-purin-9-yl)-2-(benzyloxymethyl)cyclopentanol CAS No：142217-78-5第6步：(2R,3S,5S)-3-(benzyloxy)-5-(6-(benzyloxy)-2-((4-methoxyphenyl) diphenylmethylamino)-9H-purin-9-yl)-2-(benzyloxymethyl)cyclopentanone CAS No 142217-79-6第7步：6-(benzyloxy)-9-((1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl)-N-((4-methoxyphenyl)diphenylmethyl) -9H-purin-2-amine CAS No 142217-80-9第8步：6-(benzyloxy)-9-((1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2- methylenecyclopentyl)-9H-purin-2-amine CAS No 204845-95-4钆双胺一水物122795-43-1阿折地平中间体阿折地平中间体 CAS：18621-17-5阿折地平中间体 CAS：116574-14-2阿折地平中间体 CAS：170749-59-4阿折地平中间体 CAS：39562-25-9Anagrelide阿那格雷中间体N-(6-硝基-2.3-二氯苄基)甘氨酸乙酯盐酸盐N-(2.3-dichloro-6-nitrobenzyl)glycine HCl 含量：98%以上 99%N-(6-氨基-2.3-二氯苄基)甘氨酸乙酯Ethyl N-(6-amino-2.3-dichlorobenzyl)glycine 70406-92-7Prasugrel普拉格雷侧链(中间体)150322-73-9 含量：98%以上Adapalene 阿达帕林中间体：2-(1-Adamantyl)-4-bromophenol2-(1-金刚烷基)-4-溴苯酚2-(1-Adamantyl)-4-bromoanisole2-(1-金刚烷基)-4-溴苯甲醚Methyl 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoate6-[3-(1-金刚烷基)-4-甲氧基苯基]-2-萘甲酸甲酯1-(5-Bromo-2-Methoxyphenyl)-adamantane CAS NO.104224-63-7 1-（5-溴-2-甲氧基苯基）金刚烷Methyl 6-bromo-2-naphthoate6-溴－2－萘甲酸甲酯Adefovir Dipivoxil 阿徳福韦酯中间体：9-[2-(Diethylphosphonomethoxy)ethyl]adenine9-[2-(二乙基膦酸基甲氧基)乙基]腺嘌呤9-(2-Phosphonylmethoxyethyl]adenine(Adefovir)9-[2-(膦酸基甲氧基)乙基]腺嘌呤（阿德福韦）Amorolfine HCl 盐酸阿莫罗芬中间体：3-[1,1-Dimethylphenyl-4-]-2-methyl-propionic acid3-[1,1-二甲基苯基-4-]-2-甲基-丙酸Anagrelide 阿那格雷中间体：Ethyl N-(2,3-dichloro-6-amino benzyl)glycineN－(2,3－二氯－6－氨基－苄基)甘氨酸乙酯Aripiprazole阿立哌唑中间体：1-(2,3-Dichloro-phenyl)-piperazine hydrobromide1-(2,3-二氯苯基)-哌嗪氢溴酸盐7-(4-Bromo-butoxy)-3,4-dihydro-2(1H)-quinolinone7-(4-溴丁氧基)-3,4-二氢-2(1H)-喹啉酮Brompheniramine Maleate马来酸溴苯那敏中间体：α-(p-Bromophenyl)-α-(β-dimethylaminoethyl)-2-pyridylacetonitrile maleateα-对溴苯基-α-（β-二甲基氨基乙基）-2-吡啶乙腈马来酸盐Candesartan Cilexetil 坎地沙坦酯中间体：Cyclohexyl 1-chloroethylcarbonate环己基1-氯乙基碳酸酯2-Ethoxy-1-[[2’-(1H-tetrezol-5-yl)biphenyl-4-yl]-methyl]benzimidazole-7-carboxylic acid (Candesartan)1-[[2'-(1-H-四氮唑-5-基)联苯-4-基]甲基]-2-乙氧基-苯并咪唑-7-羧酸（坎地沙坦）Cefepime头孢吡肟中间体：(6R, 7R)-7-Amino-3-[(1-methyl-1-pyrrolidino)methyl]ceph-3-em-4-carboxylate hydriodic acid 7-氨基-3-[(1-甲基-1-吡咯烷基)甲基]头孢-3-烯基-4-羧基氢碘酸盐（头孢吡肟母核）Cefutibuten 头孢布烯中间体：(E/Z) (4-2-Methyl-buten) 4-(2-benzyloxycarbonyolaminothiazol-4-yl)-4-carboxy-3-butyrate (Cefutibuten side chain)(顺/反)4－(2－苄氧羰基氨基噻唑－4－基)－4－羧基－3－丁烯酸(4－2－甲基－2－丁烯)酯（头孢布烯侧链）Dofetilide 多非利特中间体：2-[4-Nitrophenoxy]ethyl chloride4-(2-氯乙氧基)硝基苯N-Methyl-4-nitrophenethylamine hydrochloride CAS: 166943-39-14-硝基-β-苯乙胺盐酸盐N-Methyl-N-[2-(4-nitrophenoxy)ethyl]-4-nitrophenylamineN-甲基-N-[2-(4-硝基苯氧基)乙基]-4-硝基苯乙胺Escitalopram Oxalate草酸依地普仑中间体：(-)-4-[4-(Dimethylamino)-1-(4’-fluorophenyl)-1-hydroxy-1-butyl]-3-(hydroxymethyl)benzonitrile, Tosyltartaric acid salt(-)-4-[4-二甲氨基-1-(4-氟苯基)-1-羟基-1-丁基]-3-羟甲基苯乙腈，苯甲酰基酒石酸盐Finasteride非那雄胺中间体：3-Oxo-4-androstene- 17β-carboxylic acid3-氧代-4-雄甾烯-17β-羧酸Fluoxetine 氟西汀中间体：N-Methyl-3-phenyl-3-hydroxypropylamineN-甲基-3-苯基-3-羟基丙胺Lafutidine 拉呋替丁/拉夫替丁中间体：2-Bromo-4-(1-piepridinomethyl)pyridine2-溴-4-(1-哌啶基甲基)吡啶p-nitrophenyl 2-[(furanylmethyl)sulfinyl]acetic acid （For Lafutidine）a-（2-呋喃甲基亚磺酰基）乙酸-（4-硝基苯酚）酯CAS号为123855-55-0N-{4-[4-(1-Piperidinomethyl)pyridyl-2-oxy]-cis-2-buten}phthalimide maleate CAS No.146447-26-9N-{4-[4-(1-哌啶甲基)吡啶-2-氧]-顺-2-丁烯基}邻苯二甲酰胺,马来酸盐2-(Furfurylsulfinyl)acetic acid p-nitrophenyl ester2-呋喃甲基亚磺酰基乙酸-p-硝基苯Levetiracetam 左乙拉西坦中间体：L-2-Amino butanamideL－2－氨基丁酰胺Levosimendan左西孟旦中间体：6-(4-Aminophenyl)-4, 5-dihydro-5-methyl-3(2H)-pyridazinone CAS:36725-28-7 6-(4-氨基苯基)-5-甲基-4,5- 二氢-3(2H)-哒嗪酮2,7-dichloro-9H-Fluorene CAS: [7012-16-0](-)-6-(4-Aminophenyl)-4, 5-dihydro-5-methyl-3(2H)-pyridazinone(-)-6-(4-氨基苯基)-5-甲基-4,5- 二氢-3(2H)-哒嗪酮Liranaftate利拉萘酯中间体：2-Methoxy-6-methylaminopyridine2-甲氧基-6-甲氨基吡啶5,6,7,8-Tetrahydro-2-naphthol5,6,7,8-四氢-2-萘酚Nevirapine奈韦拉平中间体：2-Chloro-3-amino-4-methylpyridine2－氯－3－氨基－4－甲基吡啶Nifekalant 尼非卡兰中间体：6-Chloro-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione1, 3-二甲基-6-氯尿嘧啶N-(2-Hydroxyethyl)-N-[3-(4-nitrophenyl)propyl]amineN-(2-羟乙基)-3-(4-硝基苯基)丙胺Pramipexole普拉克索中间体：4-[(N-Benzoyl)amino]-cyclohexanone4-[(N-苯甲酰基)-氨基]-环己酮(S)-2-Amino-6-propylamino-4,5,6,7-tetrahydrobenzthiazole(S)-2-氨基-6-丙胺基-4,5,6,7-四氢苯并噻唑Prulifloxacin 普卢利沙星中间体：Ethyl 6,7-difluoro-1-methyl-4-oxo-4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylate6,7－二氟－1－甲基－4－氧代－4H－[1,3]硫氮杂环丁烷[3,2-a]喹啉－3－甲酸乙酯Ethyl6-fluoro-7-(1-piperazinyl)-1-methyl-4-oxo-4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylate6－氟－7－(1－哌啶基)－1－甲基－4－氧代－4H－[1,3]硫氮杂环丁烷[3,2-a]喹啉－3－甲酸乙酯6-Fluoro-7-(1-piperazinyl)-1-methyl-4-oxo-4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acid 6－氟－7－(1－哌啶基)－1－甲基－4－氧代－4H－[1,3]硫氮杂环丁烷[3,2-a]喹啉－3－甲酸Racecadotril消旋卡多曲中间体：3-Acetylthio-2-benzylpropanoic acid2-苄基-3-硫代乙酰基丙酸Glycine benzyl ester p-tosylate甘氨酸苄酯对甲苯磺酸盐Risperidone利培酮中间体：6-Fluoro-3-(tetrahydropyridine-4-yl)benzo[b]isoxazol6-氟-3-(4-哌啶基)-1,2-苯并异噁唑3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidine-4-one3-(2-氯乙基)-6,7,8,9-四氢-2-甲基-4H吡啶并[1,2-α]嘧啶-4-酮Rosiglitazone 罗格列酮中间体：5-{4-{2-[Methyl－(2－pyridyl)amino]ethoxy}benzal}-2,4-thiazole-dione5-{4-{2-[甲基-(2-吡啶基)氨基]乙氧基}苄叉}-2,4-噻唑二酮2,4-Thiazolidinedione2,4-噻唑二酮Roxatidine Acetate HCl盐酸罗沙替丁醋酸酯中间体：3-(1-Piperidinylmethyl)phenol3－(1－哌啶基甲基)苯酚N-{3-[3-(1-Piperidinylmethyl)phenoxy]propyl}amineN-{3-[3-(1-哌啶基甲基)苯氧基]}丙胺Telmisartan 替米沙坦中间体：N-Methyl-O-phenylenediamine dihydrochlorideN-甲基邻苯二胺盐酸盐2-N-Propyl-4-methyl-6-carboxybenzimidazole2-丙基-4-甲基-6-羧基苯并咪唑tert-Buthyl 4’-methylbiphenyl-2-carboxylate4'-甲基联苯-2-甲酸叔丁酯tert-Buthyl 4’-(bromomethyl)biphenyl-2-carboxylate4'-溴甲基联苯-2-甲酸叔丁酯Trospium Chloride曲司氯铵中间体：α-Hydroxy-α-phenylbenzeneacetic acidα-羟基-α-苯基苯乙酸Voriconazole伏立康唑中间体：6-(1-Bromo-ethyl)-4-chloro-5-fluoropyrimidine6-(1-溴乙烷)-4-氯-5-氟嘧啶1-(2,4-Difluorophenyl)-2-(1H-1,2,4-triazol-1-yl)-1-ethanone1-(2,4-二氟苯基)-2-(1H-1,2,4-三唑)-1-基)乙酮(2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)- 1-(1H-1,2,4-triazol- 1-yl)-2- butanol hydrochloride(2R,3S/2S,3R)-3-(4-氯-5-氟嘧啶-6-基)-2-(2,4-二氟苯基)-1-(1H-1,2,4-三唑-1-基)丁-2-醇盐酸盐(2R,3S/2S,3R)-3-(5-Fluoro-4-pyrimidinyl)-2-(2,4-difluorophenyl)- 1-(1H-1,2,4-triazol- 1-yl)-2- butanol(2R,3S/2S,3R)－3－(5－氟嘧啶－4－基)－2－(2,4－二氟苯基)－1－(1H－1,2,4－三唑－1－基)丁－2－醇Ziprasidone齐拉西酮中间体：3-(1-Piperazinyl)-1,2-benzisothiazole hydrochloride3-(1-哌嗪基)-1,2-苯并异噻唑盐酸盐Zolmitriptan佐米曲坦/佐米曲普坦中间体：(S)-4-(4-Nitrobenzyl)-1,3-oxazolidin-2-one(S)-4-(4-硝基苄基)-1.3-噁唑-2-酮Memantine美金刚中间体：1-bromo-3,5-dimethyl adamantane1-溴-3,5-二甲基金刚烷甲磺酸伊马替尼及中间体甲磺酸伊马替尼220127-57-1Imatinib base 152459-95-54-[(4-methyl-1-piperaziny)methyl]benzoic acid 106261-49-84-[(4-methyl-1-piperaziny)methyl]benzoic acid dihydrochloride 106261-48-7N-(5-amino-2-methylphenl)-4-(3-pyridyl)-2-pyrimidine-amine 152460-10-1舒尼替尼及中间体舒尼替尼 341031-54-7Sunitinib base 557795-19-45-Fluoro-1,3-dihydro-indol-2-one 56341-41-42-tert-butyl 4-ethyl 3,5-dimethyl-1H-pyrrole-2,4-dicarboxylate 86770-31-24-(ethoxycarbonyl)-3,5-dimethyl-1H-pyrrole-2-carboxylic acid 5442-91-1ethyl 2,4-dimethyl-1H-pyrrole-3-carboxylate 2199-51-1ethyl 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylate 2199-59-95-Formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid 253870-02-95-((Z)-(5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylicacid 356068-93-4拉帕替尼及中间体拉帕替尼 388082-78-8Lapatinib base 231277-92-22-Amino-5-iodo-benzoic acid 5326-47-66-Iodoquinazolinone 16064-08-74-Chloro-6-iodo-quinazoline 98556-31-12-Chloro-1-(3-fluoro-benzyloxy)-4-nitro-benzene 443882-99-33-Chloro-4-(3-fluoro-benzyloxy)-phenylamine 202197-26-0N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-iodoquinazolin-4-amine 231278-20-95-[4-({3-chloro-4-[(3-fluorobenzyl)oxy] phenyl}amino)quinazolin-6-yl]-2-furaldehyde 231278-84-5尼罗替尼及中间体尼罗替尼 641571-10-04-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid 641569-94-04-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid ethyl ester3-[(Aminoiminomethyl)amino]-4-methyl-benzoic acid ethyl ester mononitrate 641569-96-2 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline 641571-11-1达沙替尼及中间体达沙替尼 863127-77-92-Amino-N-(2-chloro-6-methylphenyl)thiazole -5-carboxamide 302964-24-52-(6-chloro-2-methylpyrimidin-4-ylamino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide 302964-08-5吉非替尼及中间体吉非替尼 184475-35-2methyl 2-amino-4,5-dimethoxybenzoate 26759-46-66,7-dimethoxyquinazolin-4(3H)-one 13794-72-46-hydroxy-7-methoxyquinazolin-4(3H)-one 179688-52-93,4-dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate 179688-53-04-chloro-7-methoxyquinazolin-6-yl acetate 179688-54-1 (HCl)230955-75-64-(3-chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl acetate 184475-70-5 (HCl)788136-89-04-(3-chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol 184475-71-64-(3-chloropropyl)morpholine 7357-67-7埃罗替尼及中间体埃罗替尼/厄罗替尼 183319-69-9Erlotinib base 183321-74-6ethyl 3,4-dihydroxybenzoate 3943-89-3ethyl 3,4-bis(2-methoxyethoxy)benzoate 183322-16-9ethyl4,5-bis(2-methoxyethoxy)-2-nitrobenzoate 179688-26-7ethyl4,5-bis(2-methoxyethoxy)-2-aminobenzoate 179688-27-86,7-bis-(2-Methoxyethoxy)-quinazolin-4(3h)-one 179688-29-04-Chloro-6,7-(2-methoxyethoxy)-quinazoline 183322-18-1卡那替尼 289499-45-2凡德他尼 443913-73-3索拉非尼索拉非尼 475207-59-14-CHLORO-(2-(METHYLAMINO)-CARBONYL)-PYRIDINE 220000-87-34-(4-aminophenoxy)-N-methylpicolinamide 284462-37-9免疫抑制剂FTY720 475207-59-1抗糖尿病药西他列汀 486460-32-6维达列汀 274901-16-5盐酸度洛西汀及中间体盐酸度洛西汀 136434-34-9(S)-N,N-Dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine 132335-46-7(HCl) 阿利吉仑及中间体阿利吉仑 173334-58-2Aliskiren base 173334-57-1(2S,4S,5S)-5-amino-N-(2-carbamoyl-2-methylpropyl)-4,5-dihydroxy-2-isopropylpentanamide (R)-3,6-diethoxy-2,5-dihydro-2-isopropylpyrazine 110117-71-02-(3-methoxypropoxy)-4-((R)-2-(bromomethyl)-3-methylbutyl)-1-methoxybenzene) 172900-69 -52-(aminomethyl)-2-methylpropanamide 324763-51-1(R)-3-(3-methylbutanoyl)-4-benzyloxazolidin-2-one 145589-03-31-(((S)-2-(bromomethyl)-3-methylbutoxy)methyl)benzene 172901-00-7卡巴拉汀及中间体酒石酸卡巴拉汀129101-54-8卡巴拉汀碱123441-03-2N-Ethyl-N-Methyl carbamoyl chloride 42252-34-63-[1-(Dimethylamino)ethyl]phenol 105601-04-5(s)-3-(1-(dimethylamino)ethyl)phenol 139306-10-8罗库溴铵及中间体罗库溴铵 119302-91-95α-androsta-2-en-17-one 963-75-72-(4-morpholinyl)-16-(1-pyrrolidinyl)-5-androstane-3,17-diol 119302-20-4艾拉莫德及中间体艾拉莫德 123663-49-03-硝基-4-苯甲氧基茴香醚 82780-78-73-氨基-4-苯甲氧基茴香醚 82780-77-63-甲基磺酰胺基-4-苯氧基茴香醚 88381-56-7α-氨基-2-甲氧基-4-甲磺酰胺基-5-苯氧苯乙酮盐酸盐 149436-41-9氨来占诺及其中间体6-异丙基-4-氧代-4H-1-苯并吡喃-3-甲醛(取代苯并吡喃—3—甲醛) CAS NO: 49619-58-16-异丙基-4-氧代-4H-1-苯并吡喃-3-甲腈(取代苯并吡喃—3—甲腈) CAS NO: 50743-32-3氨来占诺乙酯瑞舒伐他汀钙及其中间体4－（4-氟苯基）－6－异丙基－2－（N－甲基－N—甲磺酰氨基）嘧啶－5－甲酸甲酯CAS : 289042-11-1 4-(4-氟苯基)－6－异丙基－2－（N－甲基－N—甲磺酰氨基）嘧啶－5－甲醇CAS: 147118-36-3 母核醇4-（4-氟苯基）－6－异丙基－2－（N－甲基－N—甲磺酰氨基）嘧啶－5－甲醛 CAS : 147118-37-4(5S)-瑞舒伐他汀缩合物乙酯瑞舒伐他汀乙酯(3R)-瑞舒伐他汀缩合物甲酯瑞舒伐他汀甲酯3-叔丁基二甲硅氧基戊二酸酐CAS: 91424-40-7(3R)-叔丁基二甲硅氧基戊二酸单甲酯CAS: 109744-49-21-乙氧羰基-5-甲基-(3R)-叔丁基二甲硅氧基戊二酸酯CAS: 158275-79-7(3R)-叔丁基二甲硅氧基-5-氧代-6-三苯基膦烯己酸甲酯[（4R-6S）-6-[（乙酰氧基）甲氧]-2，2-二甲基-1，3-二氧杂-4-基]乙酸叔丁酯侧链匹伐他汀钙及其中间体2-环丙基－4－(4－氟苯基)喹啉－3－甲醇 CAS: 121660-11-52-环丙基－4－(4－氟苯基)喹啉－3－甲醛 CAS: 121660-37-5(E)-3-[2-环丙基－4－(4－氟苯基)－3－喹啉-2-丙烯腈(E)-3-[2-环丙基－4－(4－氟苯基)－3－喹啉-2-丙烯醛CAS: 148901-68-2(E)-(5S)-7-[2--环丙基－4－(4－氟苯基)－3－喹啉] -5-羟基-3-氧代-庚-6-烯酸乙酯厄多司坦及其中间体DL- N-氯乙酰高半胱氨酸硫内酯盐酸艾司洛尔雷诺嗪及其中间体N-(2,6-二甲苯基) -2-氯乙酰胺CAS: 1311-01-7N-(2,6-二甲基苯基)-1-（1-哌嗪）乙酰胺CAS: 5294-61-1雷诺嗪醚化物盐酸雷诺嗪CAS: 95635-56-6盐酸倍他洛尔及其中间体1-[4-(2-羟乙基)苯氧基] -2, 3-环氧丙烷1-{(4-[2-(环丙基甲氧基)-乙基]-苯氧基}-2, 3-环氧丙烷倍他洛尔碱左旋倍他洛尔托美汀托美汀钠Amtolmetin Guacil呱氨托美丁:87344-06-7及其中间体顺苯磺酸阿曲库铵及其中间体四氢罂粟碱盐酸盐1, 5-戊二醇二丙烯酸酯脱甲基阿曲库铵草酸盐(R)- (-)-四氢罂粟碱盐酸盐(1R, 1’R)- 脱甲基阿曲库铵草酸盐苯磺阿曲库铵左亚叶酸钙/左旋亚叶酸钙3-甲基噻吩CAS: 616-44-4鲁米诺及其钠盐 "CAS: 521-31-3地西他滨Decitabine及其中间体替莫普利的中间体: CAS: 110221-26-6(2S,6R)-6-amino-5-oxo-2-(2-thienyl)perhydro-1,4-thiazepine (Intermediate of temocapril) (2S，6R)-6-氨基-2-2-(噻吩基）-1,4-硫氮杂卓-5-酮。

1-金刚烷甲酸酸度系数
金刚烷甲酸是一种有机化合物，也被称为白石蜡酸。

它是一种固体，常用于制造润滑剂、塑料和橡胶等。

在化学中，酸度系数是指酸的强度的度量，通常用pKa值表示。

本文将介绍金刚烷甲酸的酸度系数。

首先，我们需要了解金刚烷甲酸的化学式为C20H40O2。

它是一种脂肪酸，具有一个羧基（COOH）和一个长链烷基。

羧基是一种酸性基团，可以释放出质子（H+），使溶液呈现出酸性。

因此，金刚烷甲酸可以被视为一种弱酸。

酸度系数pKa是指在特定条件下，弱酸溶液中酸性羧基的离解常数（Ka）的负对数。

在水溶液中，金刚烷甲酸的pKa值约为4.9。

这意味着在pH值低于4.9的条件下，金刚烷甲酸会完全离解为质子和金刚烷甲酸根离子。

而在pH值高于4.9的条件下，金刚烷甲酸大部分存在于分子形式，只有少量离解为质子和金刚烷甲酸根离子。

需要注意的是，pKa值并不是一个固定的常数，它会受到很多因素的影响，如温度、离子强度、溶剂极性等。

因此，在实际应用中，需要根据具体情况来确定金刚烷甲酸的酸度系数。

总之，金刚烷甲酸的酸度系数pKa约为4.9，在水溶液中表现出弱酸性质。

了解其酸度系数有助于我们更好地理解其化学性质，并在实际应用中进行合理的设计和调整。