《医学免疫学与微生物学》试题及答案（Examination questions and answers of medical immunology and Microbiology）Examination questions and answers of medical immunology and MicrobiologyFirst, fill in the blanks (1 points per minute, 15 points)1. normal immune function showed _______________, such as the low level can lead to __________________.The 2. is ____________ and lack of ____________ substance called semi antigen.Two features of class I and class II gene gene 3. classic is __________________ and ___________________.4.CK usually in ___________ way to produce CK cells themselves, or to ___________ effects on neighboring cells.5.TCR-CD3 complex, the function of TCR is ________________, CD3 molecules through the ______________ structure in the cytoplasm, the antigen signal transduction into cells.6. bacterial structure lacks _____________, known as the L type of bacteria.The 7. main ______________ caused by typhoid fever.8. of avian influenza virus subtype is ________________.The 9. is _________________ pathogenic hantavirus.10. chemical composition of bacterial endotoxin is______________.Two, interpretation of the term (every day 3 points, a total of 15 points)1. antigen2. monoclonal antibody3. cytokines4. sepsis5. micro ecological imbalanceThree, RadioButtonList: from the following A, B, C, D 4 answers, choose 1 correct answers and the English letters in parentheses (match each 1 points, a total of 30 points)1. adaptive immunity is characterized by ()A. comes with birthB. reacts quicklyC. specificityD. without memory2. in the following description of the toxin, the error is ()A. toxoid is made from immune serum of immunized animalsB. should be done skin test before injectionC. can neutralize the toxin, may cause hypersensitivityD. is used for artificial immunity3. which of the following elevated Ig may indicate a recent infection of the body?A.IgGB.IgMC.IgED.IgA4. the elevated complement component in the serum of patients with hereditary vascular edema is ()A.C1qB.C2aC.C4aD.C95. the component of complement cleavage, which has both the action of accommodation and the action of immune adherence, is ()A.C2aB.C2bC.C5bD.C3b6. the following description of MHC is correct except ()A. a tightly linked genetic groupThe MHC of the B. is called the HLA complexThe C.HLA complex is located on chromosome seventeenthD. and cell recognition and the presentation of antigen peptide to T cells7., according to the genetic rule of the unit type, the probability of the same 2 parts of a sibling is equalA.0%B.25%C.50%D.100%8.HLA class II molecules are mainly expressed in ()A. dendritic cellsB. neutrophilsC.T cellD.NK cellThe function of 9. cytokines is ()A. specificityB. is limited by MHCC. plays a role through cytokine receptorsD. mainly functions as endocrine form10. for the description of the T cell activation second signal, the error is ()A. is also called cooperative stimulation signalB.Antigen specificC., if there is no second signal, T cells become incompetentThe combination of D. and CD28 molecules with B7 molecules is the most important second signal11., the erroneous description of NK cells is ()A. cell containing azurophilic granules. It is also called the large granular lymphocytesB. can kill some tumor cells directlyC. can also kill target cells through ADCCD. target cell is limited by MHC12., the so-called TCR antigen recognition refers to () Identification of A. TCR against primary peptides Identification of MHC molecules by B. and TCRDouble recognition of MHC: antigen peptide by C. and TCR Identification of complete antigen molecules by D. TCRThe characteristics of 13.CD8+CTL target cell are ()A. antigen free specificityB. is restricted by MHC class II moleculesC. target cells undergo lysis and apoptosisD. CTL itself is also damaged14. in type IV hypersensitivity, CD4+T cells mediate inflammatory responses, and the major inflammatory cells are ()A. macrophagesB.NK cellC. neutrophilsD.CTL15. again, the significance of antibody response in medical practice is ()A. vaccination more than two timesWhen B. serology tests for infectious diseases, they should be done at the beginning of the disease and the recovery stage, and the results are comparedC. serological diagnosis should identify nonspecific recall reactionsMore than D., all rightType 16. hypersensitivity is characterized by ()A. is mediated by antibody IgGB. damages target cells by complement and NK cellsC. does not cause tissue damageD. has obvious individual difference and genetic predisposition17. in the description of heterologous immune serum desensitization therapy, the mistake is ()A. is suitable for individuals who have been identified with allergen and are difficult to avoid contact with this allergenB. uses small doses, short intervals, and multiple injectionsC. target cells in batches desensitization, and finally sensitized state all liftedD. desensitization is temporary18. tuberculin test positive indicated ()A. has never been exposed to Mycobacterium tuberculosisB. is suffering from severe TBC. has been infected with TB and has acquired the cellular immunity against Mycobacterium tuberculosisD. has antibodies against Mycobacterium tuberculosis in vivo19., the patient's repeated local injection of insulin caused local redness, bleeding, and necrosis, and the hypersensitivity associated with this was ()Type A. hypersensitivityType B. hypersensitivityType C. hypersensitivityType D. hypersensitivity20. newborns can acquire naturally passive immunity from the mother's IgA.IgG and IgMB.IgG and SIgAC.IgA and IgMD.IgD and IgE21. the virus that produces only transient immunity afterinfection is ()A. measles virusB. Japanese encephalitis virusC. hepatitis C virusD. influenza virus22. the major bacteria associated with acute glomerulonephritis are ()Group A.A StreptococcusB. Escherichia coliCoagulase positive staphylococci C.D. coagulase negative staphylococci23. the causative substance of Clostridium difficile is mainly ()A. endotoxinExotoxin B.C. capsuleD. fimbriae24. microorganisms that are ineffective in the treatment of antibiotics are ()Mycoplasma A.Chlamydia B.C. virusD. fungi25. among the following descriptions of hepatitis A virus, the error is ()A. only causes acute infectionB. has strong resistance to the outside worldC. has a capsuleD. vaccine has a good preventive effect26. in the following description of the HIV feature, the error is ()The A. virus contains reverse transcriptaseB. has strong resistance to the outside worldC. has a capsuleD. is mainly infected with Th cells and macrophages27. microorganisms causing thrush are ()Yersinia pestis A.B. Candida albicansC. Helicobacter pyloriLeptospira D.28. in the following viruses, the nucleic acid is DNA and is ()A. hepatitis A virusB. hepatitis B virusC. rabies virusD.SARS coronavirus29. the following substances, which can be made into toxoid after formaldehyde treatment, are ()A. antibioticB. endotoxinC. antitoxinExotoxin D.30. irregular use of antibiotics can lead to antibiotic associated diarrhoea and pseudomembranous colitis, the pathogen is ()A. Candida albicansClostridium perfringens B.Clostridium difficile, C.Bacillus anthracis D.Four, to: (2 points per day, a total of 16 points)Answer the following questions: 1) note that the narrative is wrong, please carefully read each question and find out the error; 2) will be described below in the correct question blank in must not change in question; 3) according to the answer, the answer is not simple or not, or not. Is not the "noun", should express the correct meaning, nor "terminology".1. modern immunization believes that the result of an immune response is always beneficial to the organism.Corrections：A polysaccharide or protein antigen between 2. hemolyticstreptococci and a common antigen between the human colon mucosa.Corrections：3. the three activation pathways of complement have different end pathways.Corrections：4. the immune cells in quiescent state and activated state can secrete CK.Corrections：5. thymic cells obtained by positive selection have the ability to tolerate themselves.Corrections：6. in activated CD4+T cells released by CK, IL-2 is a powerful activator of monocytes / macrophages.Corrections：7. all anaerobic bacteria have spores, all of which are gram positive bacteria, all of which are bacilli.Corrections：8. Mycobacterium tuberculosis on ultraviolet light, alcohol,boiling resistance is strong, not easy to kill.Corrections：Five questions (8 points per day, a total of 24 points)What are the biological effects of 1. cell immunity?2. why can HLA genotype and / or phenotype be used in individual identification and paternity testing?3. what are the mechanisms of immune pathology mediated by cellular and humoral immunity in hepatitis B?。
