MR容量转移常数(Ktrans)对乳腺肿瘤的诊断价值研究
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of.And those area under the curve were O.900, 0.944, 0.528.Conclusion Kt… is applicable in the diferential diagnosis ofbenign and malignant breast lesions and the diag n ostic ef iciency is obviously better than that ofADC.
(mean),K (max)and the apparent difusion coef icient(ADC )of the two groups were measured and recorded Levene variance analysis and
tw o independent samples of t—test were used to compare the diferences between the tw o groups.The receiver operating characteristic curve (R OC ) analysis was used for comparing the diagnostic effectiveness betw een K ” and ADC.Results The K (mean).K (max)and ADC of breast
浙江临床医学201 8年5月第20卷第·
MR容量转移常数 (K仃粕s)对乳腺肿瘤的诊断价值研究
曾 晶晶 杨 丙奎 卜阳 阳 钱 琦 金 平 林敏 ★
【摘要 】 目的 探讨 1.5 T动态增强磁共振成像 (DCE—MRI)容量转移常数 (K )对乳腺 良恶性肿瘤的诊断价值。方法 采用1 5
【关键词 】 乳腺肿瘤 容量转移常数 表观扩散系数 动态增强磁共振成像 【Abstract】 Objective To evaluate the value of volume… fer constant(K… )of 1 5 T dynamic enhanced magnetic resonance imaging(DCE—
T MRI扫描成 像仪 和8通道 乳腺 相控 阵线 圈对乳 腺肿 块性质待 定的 患者进行DCE—MRI检查 。 多病 灶患者取 最大者 纳入 研 究,最终收 集26 个病灶 ,其病理 结果 为乳腺 癌 l6例 、乳 腺 纤维腺 瘤 104 ̄,J。测量并记 录两组病 灶的K (mean)、K” (max)、表观 扩散 系数 (ADC)。 采 用Levene方差 分析 比较两组 间差异 ,受试者特性 曲线 (ROC)描述 并 比较K 与ADc两者的诊 断效 能。结果 乳腺癌 的K” (mean) 为 (0 56±0.12)min_。、K” (max)为 (2.25±0.43)min-。、ADC值 为 (1.36±O.27)x 10-3mm /s;乳腺 纤维腺 瘤的K” (mean)为 (0.17±0 03)min- 、K” (max)为 (O.37±0 07)min_。,ADC值 (1.36±0 20)x 10一mm /s。乳腺癌与乳腺 纤维腺 瘤间K 差异 有统计学 意 义。以最大约登 指数作为最佳诊断切点值 ,即K (mean)=0.26min~、K (max)=0.58min~、ADC=1.38×10 mm /s作为阈值时 ,三者 判断乳腺 良恶性病 变的敏 感度分别为87.5%、93.8%和62.5%;特异度分别为80.O%、90.0%和60.0%;曲线下面积 分别为0 900、0.944、O.528。结 论 K 对乳腺 肿瘤 良、恶性鉴别诊断具有显著 临床价值 ,且诊 断效能明显优 于ADC。
七he specificity ofthose were 80.O% , 90.0% and 60.0% ,respectively, fo r difierential diagnosis ofbreast lesions with the maximum Youden’ index as cue
MRI)in the diferential diagnosis ofbenign and malignant breast tumors.Methods 26 patients suspected ofbreast tumour were collected and underwent DCE—M R I exam ination using 1.5 T whole—body M R scanner with a 8-channel phased—array breast coil.In the patients with multiple lesions. the m ax lesions were enrolled in the study.The pathological results w ere as follows: 16 cases were breast cancer and 10 cases were breast fibrom a.The K…