化合物简写结构对照

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DMP
Dess-Martin periodate From Iodobenzoic acid heat with AcOH then AcO2
Mild oxidizing agent for alcohols to aldehydes
O
AcO
OAc I OAc O
DMPM
3,4-Dimethoxybenzyl
Makes radicals Thiolating Reagent
NC
N N
CN
N
SS
N
Protecting group for phenols, acids and alcohols especially carbohydrates Protecting group for alcohols, amines Hindered reductant
Ligand for palladium
O
DBN DBU DCC DDQ
Strong hindered base Strong hindered base Peptide coupling reagent Oxidant
Cl Cl
N N
N N
N C N
O CN CN O
DEAD
Diethyl azodicarboxylate
O N N
O
O
HO H H O N
N
DIAD
Diisopropyl azodicarboxylate
DIBAL DIBAL-H DIC DIPEA DIEA DMD DMAP DME DMF
Diisobutylaluminium hydride
Reagent used in Mitsunobu Reaction (inversion of alcohols) Reducing agent for the selective reduction of ester to aldehydes Peptide coupling reagent Proton sponge, base
HO OH
O OsO4 + NMO + Cl O N O H H N
AE
Asymmetric epoxidation
Sharpless Conditions
OH O OH
tBuOOH
+ Ti(Oi Pr)4 +
EtO2C HO H
CO2Et H OH
AIBN Aldrithiol® All
? ,? '-Azoisobutyronitrile 2,2'-Dipyridyldisulphide Allyl
Protecting group for alcohols, phenols, acids, amides, amines and carbonyls Activating group for alcohols Fluorating reagent
O Br S R O
BTAF
N
F
Bum Bz
t-butoxymethyl Benzoyl
O O R
N O N
DMS
S
DMSO DPPA
Dimethylsulphoxide Diphenylphosphoryl azide
O S
O P O N N N O
EDCI
EDTA
1-ethyl-3-[3(dimethylamino)propyl] carbodiimide Ethylenediamminetetraacetic acid
Dabco™ DAST
1,4-Diazabicyclo[2.2.2]octane Diethylaminosuphur trifluoride
Strong hindered base Fluorinating agent
F F F S
N N
N
dba
Dibenzylideneacetone Z,Z-1,5-diphenyl-1,4-pentadien-3one 1,5-Diazabicycolo[4.3.0]non-5ene 1,8-Diazabicyclo[5.4.0]undec-7ene 1,3-Dicyclohexylcarbodiimide 2,3-Dichloro-5,6-dicyano-1,4benzoquinone
Ac Acetyl
Some Uses
Very common protecting group for alcohols and phenols Protecting group for acids, thiols and alcohols
Structures
O R
R
Ad
Adamantyl
AD
Asymmetric dihydroxylation
O
O
Cys
Cystine
Amino acid
HSOH NH2源自 © 2000 Toby Broom
No part of this document may be reproduced or modified without the express permission of Toby Broom. tbroom@
Protecting group for amines especially peptides Protecting group for alcohols, phenols, acids and amines Peptide coupling reagent
O R O
R O
Benzyloxymethyl
N
O O
N
O
O
O N
© 2000 Toby Broom
No part of this document may be reproduced or modified without the express permission of Toby Broom. tbroom@
BH 3SMe2
PPh2 PPh2
BINAPO
Phosphinous acid, diphenyl-[1,1'binapthalene]-2-2'-diyl ester
Ligand for Ru catalytic hydrogenation
OPPh2 OPPh2
Boc BOM
tert-Butoxycarbonyl
O N N
O
H Al
Diisopropylcardodiimide Diisopropylethylamine
N C N
N
Dimethyldioxorane 4-Dimethylaminopyridine Dimethoxyethane N,N-Dimethylformamide
Used for making epoxides Weak base Solvent Solvent
Benzyloxycarbonyl
COD
Cyclooctadiene
Cp
Cyclopentadienyl
mCPBA
meta-chloroperoxybenzoic acid
Very common protecting group for amines especially in amino acids Ligand for transition metal catalysts and used to make 9-BBN As it’ anion a ligand for s transition metals and a common Diels-Alder Diene Oxidising agent used for making epoxides and Baeyer-Villiger reaction
© 2000 Toby Broom
No part of this document may be reproduced or modified without the express permission of Toby Broom. tbroom@
Abbreviation Full Name
BBN
R
R
Alloc 9-BBN
Allyloxycarbonyl 9-Borabicyclononane
O O
H B
BMS BINAP
Borane-methylsulphide complex 2,2'-Bis(diphenylphosphino)-1,1'binapthyl
Reducing agent Ligand for Ru catalytic hydrogenation and Buchwald reaction
DMPU
1,3-Dimethyl-3,4,5,6-tetrahydro2(1H)-pyrimidinone Dimethylsulphide
Protecting group for alcohols (can be removed in presence of MPM selectively) Non carcinogenic replacement for HMPA Used for quenching Ozonolysis and ligand for BH3 Solvent and oxidant Organic Source of Azide
Protecting group for amines and alcohols Peptide coupling reagent
O
R
O Ph P Ph F
F F F F
Fmoc
9-Fluorenylmethoxycarbonyl
Protecting group for amines, alcohols and acids (very stable to acids)