国内外急性早幼粒细胞白血病指南解读
杨晓阳;万梦婕;陈方平
【期刊名称】《白血病·淋巴瘤》
【年(卷),期】2016(025)010
【摘要】全反式维甲酸和三氧化二砷在急性早幼粒细胞白血（APL）治疗中的作用均为我国最早发现，我国对于 APL 的治疗做出了举世瞩目的贡献。但国外有关 APL 的指南中仍无我国的治疗方案，并且我国的治疗方案与国外亦不一致。文章对国内外APL 指南进行了解读，以探寻APL 的规范诊疗。通过分析我国及欧美国家的 APL 指南，展示 APL 的研究现状，探讨 APL 的研究方向。目前国内外APL 指南仍有一定差异，建议根据循证医学尽快统一APL 的诊疗规范。希望我国的治疗指南更多地依据循证医学，更能被世界接受。%The therapy of acute promyelocytic leukemia (APL) with all-trans retinoic acid and arsenic trioxide was first discovered in China, which made a great contribution worldwide to APL treatment. However, foreign guidelines did not include the Chinese chemotherapy regimens, and our regimens were inconsistent with foreign guidelines. Therefore, it is necessary to interpret the home and international guidelines and to explore standard treatment of APL by analyzing APL guidelines of the China, Europe and the United States. Owing to several discrepancies between domestic and foreign APL guidelines, unifying the APL's diagnosis and treatment standard is desperately needed at present according to the evidence-based medicine. It is hoped that Chinese chemotherapy regimens will