Clinical presentation
• Majority are symptomatic at presentation 1.肺癌生长引起局部症状 Symptoms related to lung
lesion 2.肺癌向邻近组织器官侵犯Symptoms from
intrathoracic spread 3.向其它脏器扩散 Symptoms from distant mets 4. 非转移性肺外表现 Symptoms from paraneoplastic
WHO divides lung cancer into 2 major classes based on its biology, therapy, and prognosis.
NSCLC accounts for more than 80% of all lung cancer cases, and it includes 2 形式转移:
远处 器官 转移
0期
IA期 IIB期
IIIB期
IV期
①局部直接蔓延; ②血行转移; ③淋巴道转移;
Symptoms from intrathoracic spread
Pleural or pericardial effusion Hoarseness Pancoast tumor SVC syndrome dysphagia elevated diaphragm
popular) Hepatic mets Brain mets
内分泌系统 柯兴氏综合征、糖尿病、甲亢等 神经系统 多发性肌炎、Eaton—Lambert综合 征
肺癌和遗传是有相关性的,具有遗传倾向,但不是遗传性疾病;
在家族中有肺癌病人,本人又为长期大量吸烟者,应提高警惕;