本刊专家论坛栏目介绍
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专家论坛 6冠心病的分子流行病学研究 分子流行病学的研究结果给我们提供了大量的信息和 提示,为冠心病早期诊断、防治提供新的视觉和靶点.为个体 化治疗奠定基础。但单个研究的结果尚需要更多的研究来验 证,因此冠心病分子流行病学的研究任重而道远。 【参考文献】 [I】Teupser D'Mueller M Koglin J.et o1.CD36 mRNA expression is increased in CD14+monocytes of patients with coronary heart disease 【J】.Clin Exp Pharmacol Physiol,2008,35(5-6):552-556. [2】Majeed Miller M.Low high-density lipoprotein cholesterol:an important consideration in coronary heart disease risk assessment[J].Curr Opin Endocrinol Diabetes Obes,2008,15(2):175—181. 【3】Florentin M,Libempoulos EN,Wierzbicki AS,et a1.Multiple actions of high—density lipoprotein[J].Curt Opin Cardiol,2008,23(4):370—378. [4]4 Aronson D.Hyperglycemia and the pathobiology of diabetic complications 【J】.Adv Cardiol,2008,45:1—16. [5】Urbich C,Dernbach E,R ssig L,et .High glucose reduces cathepsin L activity and impairs invasion of circulating progenitor cells[J].J Mol Cell Cardiol,2008,45(3):429-436. [61 Linke Erbs s,Hambrecht R Effects of exercise training upon endothelial function in patients with cardiovascular disease[j].Front Biosci,2008,1 3: 424-432. [7】Catakoglu AB,Duman BS,Kurtolu H,et .Common variants in the ATP-binding cassette transporter 1 gene with decreased HDL— cholesterol levels and coronary artery disease[J1.Arch Med Res, 2008,39(8):735—742. [81 Tang NP,Wang Ls,Yang L,et .Genetic variant in glutathione peroxidase 1 gene is associated with an increased risk of coronary artery disease in a Chinese population[J].Clin Chim Acta,2008,395(1—2):89— 93. [9]Di Castelnuovo A,Soccio M,et .The C242T polymorphism of the p22phox component of NAD(P)H oxidase and vascular risk.Two case— control studies and a meta-analysis….Thromb Haemost,2008,99(3): 594-601 2009年3月第6卷第7期 [101 Popov AF,Schuh EG,Hinz J,et .Impact of endothelin一1 Lys198Asn polymorphism on coronary artery disease and endorgan damage in hypertensives[J].Coron Artery Dis,2008,19(7):429-434. 【1 1]Zak I,Sarecka B,Krauze J.Synergistic effects between 561A>C and 98G>T polymorphisms of E—selectin gene and hypereholesterolemia in determining the susceptibility to coronary artery disease『j1.Heart Vessels,2008,23(4):257-263. [12]Biselli PM,Guerzoni AR,de Godoy MF,et .Vascular endothelial growth factor genetic variability and coronary artery disease in Brazilian population[J].Heart Vessels,2008,23(6):371-375. 【13]Jemaa R,Rojbani H,Kallel A,et 01.Association between the-2518G/ A polymorphism in the monoeyte chemoattmctant protein一1(MCP一1) gene and myocardial infarction in Tunisian patients[J].Clin Chim Acta, 2008,390(1—2):122—125. [14]Sarecka B,Zak I,Krauze J.Synergistic effects of the polymorphisms in the PAI一1 and IL-6 genes with smoking in determining their associated risk with coronary artery disease[J].Clin Biochem,2008,41 (7-8):467-473. 【15J Vogiatzi K Apostolakis S,Voudris v,et 01.Interleukin 8 and susceptibility to coronary artery disease:a population genetics perspective[J】.J Clin Immunol,2008,28(4):329-335. [16]Jemaa R,Achouri A,Kallel A,et Association between the 2756A> G variant in the gene encoding methionine synthase and myocardial infarction in Tunisian patients[J】.Clin Chem Lab Med,2008,46 (10):1364—1368. 【17】Abdullah KG,Li L'Shen GQ,et .Four SNPS on chromosome 9p21 confer risk to premature.familial CAD and MI in an American Caucasian population(GeneQuest)IJ】.Ann Hum Genet,2008,72(Pt 5):654—657. [1 8】van der Net JB,Oosterveer DM,Versmissen J,etⅡf.Replication study 0f 10 genetic polymorphisms associated with coronary heart disease in a specific high—risk population with familial hypereholesterolemia[J]. Eur Heart J,2008,29(18):2195—2201. (收稿日期:2008—12—26)
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