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排名商品名通用名生产厂家总销售额($000)与2008年相比增幅%1立普妥Lipitor阿托伐他汀atorvastatin辉瑞Pfizer Inc5,363,193,000-8.80%2耐信Nexium埃索美拉唑esomeprazole阿斯利康AstraZeneca Pharmaceuticals5,014,827,000 4.60%3波利维Plavix氯吡格雷clopidogrel百时美施贵宝Bristol-Myers Squibb Company4,223,124,00011.20%4AdvairDiskus氟替卡松+美沙特罗fluticasone andsalmeterol葛兰素史克GlaxoSmithKline3,653,410,000 2.30%5(1)思瑞康Seroquel喹硫平quetiapine阿斯利康AstraZeneca Pharmaceuticals3,117,591,0007.20%6(6)安立复Abilify阿立哌唑aripiprazole百时美施贵宝Bristol-Myers Squibb Company3,083,351,00030% 7顺尔宁Singulair孟鲁司特montelukast默克Merck & Co., Inc.3,027,378,000 4.50%8(1)奥施康定OxyContin氧可酮（羟考酮）oxycodone普渡制药Purdue Pharma LP3,020,239,00020.70%9(1)艾可拓Actos吡格列酮（口服）pioglitazone(oral)武田制药公司北美公司Takeda Pharmaceuticals NorthAmerica, Inc2,531,621,000 3.40%10(5)普托平Prevacid兰索拉唑lansoprazole武田制药公司北美公司TakedaPharmaceuticals North America,Inc2,508,555,000-23.90%11(3)欣百达Cymbalta度洛西汀duloxetine礼来Eli Lilly and Company2,404,353,00010.80%12(4)怡诺思Effexor XR文拉法辛缓释胶囊Venlafaxine惠氏Wyeth2,385,507,000-10.20%13(2)来士普Lexapro西酞普兰escitalopram美国森林制药公司Forest Pharmaceuticals, Inc2,334,422,000-3.20%14(3)可定Crestor瑞舒伐他汀rosuvastatin阿斯利康AstraZeneca Pharmaceuticals2,308,138,00037.70%15再普乐Zyprexa奥氮平olanzapine礼来Eli Lilly and Company1,855,436,000 6.10%16维德思Valtrex伐昔洛韦valacyclovir葛兰素史克GlaxoSmithKline1,754,727,000 4.20%17(10)Flomax 坦洛新（坦索罗辛）tamsulosin勃林格殷格翰制药Boehringer IngelheimPharmaceuticals, Inc1,556,273,00025.80%18(3)来得时Lantus甘精胰岛素insulin glargine赛诺菲-安万特Sanofi-Aventis1,512,403,000 2.50%19(5)乐瑞卡Lyrica普瑞巴林pregabalin辉瑞Pfizer Inc1,445,445,0004%20西乐葆Celebrex塞来昔布（口服）celecoxib (oral)辉瑞Pfizer Inc1,437,539,000-5.80%21(1)Levaquin 左氧氟沙星（口服）levofloxacin (oral)杨森公司Janssen Pharmaceuticals, Inc1,373,131,000-6%22(9)安理申Aricept多奈哌齐（口服）donepezil (oral)卫材Eisai Corporation1,347,293,00017.20%23(9)思力华Spiriva噻托溴铵吸入剂tiotropiuminhalation勃林格殷格翰制药Boehringer IngelheimPharmaceuticals, Inc1,338,252,00017.10%24(1)代文Diovan缬沙坦valsartan诺华Novartis Corporation1,328,515,000 3.50%25(4)复代文Diovan HCT缬沙坦+氢氯噻嗪Valsartan/Hydrochlorothiazide诺华Novartis Corporation1,244,245,000 2.60%26Tricor 非诺贝特fenofibrate雅培Abbott Laboratories1,224,894,000-2%27(6)专注达Concerta哌甲酯（口服）methylphenidate(oral)强生子公司Ortho-McNeil-JanssenPharmaceuticals, Inc.1,180,887,0007%28(13)Januvia 西他列汀sitagliptin默克Merck & Co., Inc.1,145,933,00025.40%29(11)葆至能Vytorin依折麦布+辛伐他汀ezetimibe andsimvastatin默克Merck & Co., Inc.1,133,438,000-26.70%30(7)Adderall XRExtended-ReleaseCapsules安非他命/右旋安非他命Amphetamine/Dextroamphetamine美国希雷公司Shire US Inc1,130,274,000-21.90%31(9)Lovenox依诺肝素enoxaparin赛诺菲-安万特Sanofi-Aventis1,075,620,00017.70%32(7)Atripla 依非韦伦+恩曲他滨+替诺福韦efavirenz,emtricitabine, and吉利德科技公司GileadSciences, Inc.1,064,056,00016.20%33(3)益适纯Ezetrol依折麦布ezetimibe先灵葆雅Schering-Plough1,025,238,000-13.40%34Aciphex 雷贝拉唑rabeprazole卫材Eisai Corporation996,052,000-5.30%35(8)安必恩Ambien CRExtended-ReleaseTablets唑吡坦Zolpidem赛诺菲-安万特Sanofi-Aventis983,296,00013.60%36(2)万艾可Viagra西地那非（口服）sildenafil (oral)辉瑞Pfizer Inc974,727,000 5.90%37(24)妥泰Topamax托吡酯topiramate杨森制药JanssenPharmaceuticals, Inc939,312,000-55.90%38(2)赛露鹰Xylocaine利多卡因局麻药lidocaine topical恩多制药公司EndoPharmaceuticals937,263,000-3.40%39(33)ProAir HFA沙丁胺醇Albuterol梯瓦制药Teva Pharmaceuticals935,532,00077.30%40()诺和锐NovoLog门冬胰岛素insulinaspart丹麦诺和诺德公司NovoNordisk Inc.905,235,00026.60%41(29)Suboxone 丁丙诺啡+纳洛酮buprenorphine andnaloxone英国利洁时公司Reckitt BenckiserPharmaceuticals Inc.894,208,00068.10%42内舒拿Nasonex莫米松鼻用制剂先灵葆雅Schering-Plough893,579,000-1.20%43(1)Provigil莫达芬尼modafinil瑟法隆Cephalon, Inc.883,339,000 4.40%44(1)Geodon Oral齐拉西酮ziprasidone辉瑞Pfizer Inc873,952,0009.60%45(1)Truvada 恩曲他滨+替诺福韦emtricitabine andtenofovir吉利德科技公司GileadSciences, Inc.862,711,00011.20%46(1)Lunesta 艾司佐匹克隆eszopiclone赛普拉科Sepracor Inc. (renamedSunovion Pharmaceuticals Inc)813,087,000 5.50%47(4)优泌乐Humalog赖脯胰岛素insulinlispro礼来Eli Lilly and Company757,108,0007.70%48(8)诺之平Niaspan烟酸（niacin(nicotinic acid)雅培Abbott Laboratories716,589,00012.20%49(3)得妥DetrolLAExtended-ReleaseCapsules托特罗定Tolterodine辉瑞Pfizer Inc711,749,000 2.10%50(11)优思明Yasmin屈螺酮+炔雌醇drospirenone andethinyl estradiol拜耳Bayer HealthcarePharmaceuticals701,540,00019.80%51(3)科素亚Cozaar氯沙坦losartan默克Merck & Co., Inc.697,815,000 1.10%52(11)Namenda美金刚memantine 美国森林制药公司ForestPharmaceuticals, Inc670,226,00015.10%53(43)Vyvanse 赖右苯丙胺lisdexamfetamine美国希雷公司Shire US Inc660,109,00076%54(68)达菲Tamiflu奥司他韦oseltamivir罗氏Roche Pharmaceuticals651,444,000136.80% 55(11)希爱力Cialis他达拉非tadalafil礼来Eli Lilly and Company650,494,00017.20%56(8)瑞宁得Arimidex阿那曲唑anastrozole阿斯利康AstraZenecaPharmaceuticals640,326,00012.60%57(9)恩利Enbrel依那西普etanercept安进公司Amgen Inc.638,695,000-16.40%58(9)辅舒酮Flovent HFAAerosolInhaler氟替卡松Fluticasone HFA葛兰素史克GlaxoSmithKline621,041,00012.30%59(52)来得时笔芯/预填充LantusSoloStarCartridgeSystems甘精胰岛素InsulinGlargine赛诺菲-安万特Sanofi-Aventis 610,161,00093.10%60(5)可必特Combivent沙丁胺醇+异丙托溴铵吸入剂albuterol andipratropium(inhalation)勃林格殷格翰制药BoehringerIngelheim Pharmaceuticals, Inc608,121,0008.90%61(6)普米克令舒PulmicortRespulesSuspension布地奈德Budesonide阿斯利康AstraZenecaPharmaceuticals607,397,000-6.70%62(2)百泌达Byetta艾塞那肽exenatide阿米林制药公司AmylinPharmaceuticals, Inc.554,861,000-6.70%63(11)BenicarHCT氢氯噻嗪+奥美沙坦Hydrochlorothiazide/Olmesartan第一制药三共株式会社DaiichiSankyo553,640,0007.50%64(24)AndroGel 睾丸酮testosteronetopical (patches andgel)法国苏威制药SolvayPharmaceuticals, Inc.546,994,00024%65(3)普乐可复Prograf他克莫司tacrolimus(oral)安斯泰来Astellas Pharma US541,151,000-7.40%66(5)海捷亚Hyzaar氢氯噻嗪+氯沙坦hydrochlorothiazideand losartan默克Merck & Co., Inc.539,827,000 2.20%67(19)Benicar奥美沙坦olmesartan 第一制药三共株式会社DaiichiSankyo526,569,00015.60%68(1)倍美力Premarintabs结合雌激素（口服）conjugatedestrogens (oral)惠氏Wyeth520,151,000-5.20%69(18)伊马替尼Gleevec伊马替尼imatinib诺华Novartis Corporation519,508,00015.30%70(3)锐艾妥Reyataz阿扎那韦atazanavir百时美施贵宝Bristol-MyersSquibb Company519,018,000-0.10%71(6)Boniva 伊班膦酸钠ibandronate sodium罗氏Roche Pharmaceuticals511,277,000-0.20%72(6)择思达Strattera托莫西汀atomoxetine礼来Eli Lilly and Company511,187,000-0.10%73(54)利必通Lamictal拉莫三嗪lamotrigine葛兰素史克GlaxoSmithKline498,599,000-67.60%74(1)Synthroid 左旋甲状腺素levothyroxine雅培Abbott Laboratories495,523,000-3.80%75(7)Asacol 美沙拉嗪（口服）mesalamine (oral)宝洁Procter & Gamble491,311,000 5.90%76(63)信必可都保Symbicort布地奈德+福莫特罗吸入剂budesonideand formoterolinhalation阿斯利康AstraZenecaPharmaceuticals487,690,000105%77(8)修美乐Humira Pen阿达木单抗adalimumab雅培Abbott Laboratories487,601,00027.80%78(32)Solodyn 米诺环素minocycline美国麦蒂斯公司MedicisPharmaceutical Corporation479,365,00051.70%79(31)恩利EnbrelSureclick依那西普etanercept安进公司Amgen Inc.479,132,00010.50%80(22)畅沛Chantix伐尼克兰varenicline辉瑞Pfizer Inc472,207,000-22% 81(1)Skelaxin美他沙酮metaxalone美国伊兰公司Elan Corporation472,083,000-5.80%82(32)骁悉CellCept吗替麦考酚酯（口服/注射）mycophenolatemofetil(oral/injection)罗氏Roche Pharmaceuticals468,229,000-34.20%83(2)易维特Evista雷洛昔芬raloxifene(oral)礼来Eli Lilly and Company466,955,000-6.60%84(16)潘妥洛克Protonix泮托拉唑pantoprazole惠氏Wyeth461,079,000-16.60%85(1)适利达Xalatan拉坦前列素眼用制剂latanoprostophthalmic辉瑞Pfizer Inc457,121,0000.20%86(37)Actonel利塞膦酸risedronate宝洁Procter & Gamble435,977,000-39%87(12)Copaxone 格拉替雷（注射）glatiramer赛诺菲Sanofi-Aventis428,384,00015.60%88(13)弗隆Femara来曲唑letrozole诺华Novartis Corporation427,132,00018.30%89(19)Mirapex 普拉克索（口服）pramipexole (oral)勃林格殷格翰制药BoehringerIngelheim Pharmaceuticals, Inc417,934,00024.60%90(10)Avodart度他雄胺dutasteride葛兰素史克GlaxoSmithKline416,285,00014.10%91 (15)文迪雅Avandia 罗格列酮（口服）rosiglitazone (oral)葛兰素史克GlaxoSmithKline407,906,000-20.60%92 (7)修美乐Humira阿达木单抗adalimumab雅培Abbott Laboratories402,654,000-11.70%93 (13)NovoLogMix 70/30Cartridges门冬胰岛素精蛋白+门冬胰岛素InsulinAspartProtamine/Insulin Aspart丹麦诺和诺德公司NovoNordisk Inc.400,683,00015.40%94安博维Aprovel伊贝沙坦irbesartan百时美施贵宝Bristol-MyersSquibb Company 398,768,000-1.70%95 (12)Restasis环孢霉素眼用制剂cyclosporine ophthalmic 爱力根公司Allergan, Inc 398,143,00017.40%96 (31)诺和平Levemir 地特胰岛素insulin detemir 丹麦诺和诺德公司Novo Nordisk Inc.394,246,00053.90%97 (7)拜复乐Avelox莫西沙星moxifloxacin拜耳Bayer Healthcare Pharmaceuticals388,933,000-9.30%98 (17)卫喜康Vesicare索利那新solifenacin 安斯泰来Astellas Pharma US 379,283,00026.80%99 (41)Janumet 二甲双胍+西他列汀metformin and sitagliptin默克Merck & Co., Inc.378,837,00059.60%100 (4)Sensipar 西那卡塞cinacalcet 爱力根公司Amgen Inc.369,011,000 5.90%101 (4)Aldara 咪喹莫特Imiquimod美国Graceway Pharmaceuticals,LLC366,825,000 5.50%102 (4)Xopenex盐酸左旋沙丁胺醇LEVALBUTEROL HYDROCHLORIDE赛普拉科Sepracor Inc. (renamedSunovion Pharmaceuticals Inc)356,898,000-4.10%103 ()Seroquel XR 喹硫平喹硫平Quetiapine阿斯利康AstraZenecaPharmaceuticals 356,402,000151.80%104 (9)Focalin XR 哌醋甲酯的单一异构体Dexmethylphenidate 诺华Novartis Corporation352,024,00013.60%105(12)RenaGel司维拉姆/磷能解锭sevelamer美国健赞Genzyme Corporation 351,383,000-14%106 (4)Avalide 厄贝沙坦+氢氯噻嗪irbesartan,hydrochlorothiazide 百时美施贵宝Bristol-MyersSquibb Company 350,462,000-1.50%107(70)Keppra 开浦兰左乙拉西坦Levetiracetam 优时比制药UCB Inc.339,978,000-63.90%108(6)ActoplusMet二甲双胍+吡格列酮Metformin+Pioglitazone日本武田TakedaPharmaceuticals North America,Inc338,930,00012.50%109()Caduet 氨氯地平+阿托伐他汀amlodipine andatorvastatin辉瑞Pfizer Inc331,382,000-15%110()Lotrel 氨氯地平+贝那普利amlodipine andbenazepril诺华Novartis Corporation323,873,000-12%111 (13)NuvaRing雌二醇+依托孕烯ethinyl estradiol andetonogestrel默克Merck & Co., Inc.318,518,00019.20%112Norvir爱治威利托那韦 ritonavir雅培Abbott Laboratories311,949,0000.20%113 (16)克力芝Kaletra洛匹那韦+利托那韦Lopinavir/RitonavirOral Solution雅培Abbott 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阿斯利康AstraZenecaPharmaceuticals242,561,00071%138 (10)Maxalt利扎曲普坦Rizatriptan默克Merck & Co., Inc.240,341,0009.90%139 (20)Nasacort AQ曲安奈德Triamcinolone赛诺菲-安万特Sanofi-Aventis239,549,000-16.10%140 (10)斯沃Zyvox利奈唑胺LinezolidTablets辉瑞Pfizer Inc238,542,000-4.50%141 (54)Opana ER盐酸羟吗啡酮Oxymorphone恩多制药Endo Pharmaceuticals235,624,00051.40%142 (24)Procrit阿法依泊汀epoetinalfa强生子公司Centocor OrthoBiotech, Inc233,804,000-18.80%143 (12)Tussionex马来酸氯苯那敏+氢可酮chlorpheniramineand hydrocodone赛诺菲-安万特Sanofi-Aventis232,821,000-5.60%144 (87)WellbutrinXL安非他酮Bupropion加拿大凡利亚国际制药ValeantPharmaceuticals International231,227,000-62.30%145()Exforge 氨氯地平/缬沙坦amlodipine andvalsartan诺华Novartis Corporation228,459,00053.40%146 (10)达芙文Differin阿达帕林adapalenetopical法国高德美GaldermaLaboratories227,198,000-5.20%147()优泌乐25HumalogMix 75/25Pen赖脯胰岛素+鱼精蛋白 insulin lisproand insulin lisproprotamine礼来Eli Lilly and Company226,135,000-0.40%148 (27)双汰芝Combivir拉米夫定+齐多夫定lamivudine andzidovudine葛兰素史克GlaxoSmithKline225,097,000-18.40%149(3)Vigamox 莫西沙星眼药moxifloxacinophthalmic爱尔康Alcon Laboratories, Inc.224,627,000 1.80%150(6)韦瑞德Viread替诺福韦tenofovir吉利德科技公司GileadSciences, Inc.223,915,0007.90%151()Trilipix 非诺贝酸fenofibricacid雅培Abbott Laboratories221,001,000NA152(3)CiprodexOtic地塞米松+环丙沙星ciprofloxacin anddexamethasone爱尔康Alcon Laboratories, Inc.218,781,000 5.30%153 (104)Actonel 150利塞膦酸钠risedronate宝洁Procter & Gamble210,266,000339.30%154()Maxalt MLT 利扎曲普坦Rizatriptan默克Merck & Co., Inc.210,049,0009.20%155 (27)多瑞吉Duragesic芬太尼透皮给药fentanyl transdermal杨森JANSSENPHARMACEUTICA NV209,926,000-16.60%156 (14)Asmanex莫米松吸入剂mometasoneinhalation先灵葆雅Schering-Plough206,633,00011.50%157(6)Relpax 依来曲普坦eletriptan辉瑞Pfizer Inc204,273,000-4.20%158()Entocort EC 布地奈德肠溶Budesonide阿斯利康AstraZenecaPharmaceuticals200,489,00055%159 (14)BenzaClin克林霉素与过氧化苯甲酰benzoylperoxide andclindamycin topical赛诺菲-安万特Sanofi-Aventis198,107,000-12.30%160 (22)美卡素Micardis替米沙坦Telmisartan法国勃林格殷格翰BoehringerIngelheim Pharmaceuticals, Inc197,550,00019%161 (15)Enablex达非那新darifenacin英国华纳奇考特公司WarnerChilcott197,312,00011.90%162 (11)MicardisHCT替米沙坦氢氯噻嗪Telmisartan andHydrochlorothiazide雅培Abbott Laboratories197,278,0009.40%163()Prezista地瑞那韦darunavir 强生子公司Centocor OrthoBiotech, Inc191,366,00048.10%164(2)Revlimid 雷利度胺或来那度胺lenalidomide塞尔基因Celgene Corporation190,965,000-1.80%165()苏为坦Travatan Z曲伏前列素滴眼液travoprostophthalmic solution0.004%爱尔康Alcon Laboratories, Inc.190,516,00056.90%166 (15)Amitiza鲁比前列酮lubiprostone日本武田TakedaPharmaceuticals North America,190,101,00012.10%167(7)阿法根Alphagan P溴莫尼定Brimonidine 眼力健Allergan, Inc188,803,000-3.60%168(1)派罗欣Pegasys聚乙二醇干扰素α－2a peginterferonalfa-2a罗氏Roche Pharmaceuticals188,536,0000.30%169 (17)帕坦洛Patanol盐酸奥洛他定滴眼液OlopatadineHydrochlorideEye Drops爱尔康Alcon Laboratories, Inc.187,599,000-11.30%170()优泽Xyzal 盐酸左西替利嗪LevocetirizineDihydrochlorideTablets优时比制药UCB Inc.187,542,00030%171(2)Fentora 芬太尼口服fentanyl(buccal)美国宾夕法尼亚州制药公司Cephalon, Inc.185,528,0000.20%172 (15)Catapres-TTS可乐定透皮吸收贴剂Clonidine法国勃林格殷格翰BoehringerIngelheim Pharmaceuticals, Inc184,799,000-9.70%173 (31)Clarinex地氯雷他定desloratadine先灵葆雅Schering-Plough181,215,000-22.40%174 (11)文达敏Avandamet二甲双胍+罗格列酮metformin androsiglitazone葛兰素史克GlaxoSmithKline178,188,000-7.60%175 (38)Astelin氮卓斯汀azelastinenasal梅达制药Meda Pharmaceuticals177,778,000-25.70%176(8)Ultram ER 曲马多Tramadol强生子公司Ortho-McNeil-Janssen Pharmaceuticals, Inc.174,664,000-5.70%177(6)苏维乐Zoviraxtopical阿昔洛韦acyclovirtopical葛兰素史克GlaxoSmithKline174,423,000 5.70%178 (10)万赛维Valcyte缬更昔洛韦Valganciclovir罗氏Roche Pharmaceuticals174,413,0008.60%179()桑塔Uroxatral阿夫唑嗪alfuzosin赛诺菲-安万特Sanofi-Aventis174,034,00021.60%180()Lialda 氨水杨酸mesalamine (oral)美国希雷公司Shire US Inc173,802,00054.60%181(9)Temodar 替莫唑胺temozolomide先灵葆雅Schering-Plough172,475,000-5.80%182()Pentasa 氨水杨酸mesalamine (oral)赛诺菲-安万特Sanofi-Aventis171,083,00017%183 (11)Allegra-D24 Hour非索非那定+伪麻黄碱fexofenadineand pseudoephedrine赛诺菲-安万特Sanofi-Aventis167,692,0007.20%184(1)保法止Propecia非那雄胺 finasteride默克Merck & Co., Inc.166,878,000 2.30%185()Vivelle-DOT 雌二醇透皮系统estradioltransdermal诺华Novartis Corporation 165,828,00010.90%186()Zegerid 奥美拉唑+伪麻黄碱omeprazole andsodium bicarbonate桑塔鲁斯公司Santarus, Inc.164,756,00017.70%187()PremarinVaginal结合型雌激素，阴道给药conjugatedestrogens (vaginal)惠氏Wyeth164,568,00010%188()艾斯能ExelonPatch卡巴拉汀rivastigminetransdermal诺华Novartis Corporation162,259,00074.40%189(9)Prempro 结合雌激素+ 甲羟孕酮conjugatedestrogens andmedroxyprogesterone惠氏Wyeth161,662,000 5.90%190()Prandin 瑞格列奈repaglinide (oral)丹麦诺和诺德公司NovoNordisk Inc.161,651,00010.40%191 (156)Imitrex Oral舒马普坦sumatriptan(oral/nasal)葛兰素史克GlaxoSmithKline161,167,000-83.40%192Veramyst 糠酸氟替卡松fluticasone nasal葛兰素史克GlaxoSmithKline160,387,000 1.30%193(7)Taclonex 钙泊三醇+二丙酸倍他米松betamethasone andcalcipotriene(topical)华纳奇考特公司WarnerChilcott159,082,000-1.60%194(6)XopenexHFA左旋沙丁胺醇酒石酸Levalbuterol赛普拉科Sepracor Inc. (renamedSunovion Pharmaceuticals Inc)157,588,000 3.70%195()Duac CareSystem克林霉素+过氧化苯甲酰Clindamycin/Benzoyl Peroxide史帝富药厂Stiefel Laboratories,Inc.155,643,0009.30%196(7)Klor-Con 氯化钾 potassiumchloride美国厄普舍－史密斯制药Upsher-Smith Laboratories Inc.153,842,000-3.60%197()Epipen 肾上腺素注射液epinephrine无153,802,00018.40%198(5)Avinza吗啡 morphine 国王制药King Pharmaceuticals,Inc.153,393,000-2.40%199(9)Atacand 坎地沙坦candesartan阿斯利康AstraZenecaPharmaceuticals152,603,000-4.40%200()Elmiron戊聚糖Pentosan 强生子公司Ortho-McNeil-Janssen Pharmaceuticals, Inc.150,961,00010%适应症是否在中国上市降血脂是治疗胃食管反流性疾病(GERD)是预防和治疗因血小板高聚集状态引起的心、脑及其它动脉的循环障碍疾病是治疗哮喘否治疗精神分裂症是治疗精神分裂症否治疗哮喘是用于缓解持续的中度到重度疼痛是2型糖尿病是胃溃疡、十二指肠溃疡、反流性食管炎、佐-艾（Zollinger-Ellison）综合征（胃泌素瘤）。
2011年全球销售额前100位的药品排序中文药名（药物类别）商品名销售商全球销售额(亿美元)增长率美国销售额(亿美元)增长率1 阿托伐他汀片（降血脂药）LipitorTablets辉瑞/Astellas制药/Almirall95.77 -10.8% 13.05 -75.5%2 复方氟替卡松/沙美特罗粉末吸入剂（抗哮喘药）AdvairDiskus葛兰素史克/Almirall81.32 2.3% 10.73 -73.4%3 氯吡格雷片(抗血小板聚集药）PlavixTablets赛诺菲-安万特/百时美施贵宝70.59 -22.9% 0.76 -98.8%4 利妥昔单抗（抗肿瘤药）Rituxan 中外制药/Biogen Idec/Genentech/罗氏68.63 12.3% 7.66 -73.7%5 英利昔单抗(抗风湿药) Remicade 强生/三菱田边制药/强生65.10 1% 7.76 -75%6 贝伐珠单抗注射剂(免疫调节药) AvastinInjection罗氏/Genentech60.48 -2.6% 6.96 -77.3%7 曲妥珠单抗注射剂(抗肿瘤药) HerceptinInjection罗氏60.03 15% 16.25 6.3%8 缬沙坦片（抗高血压药）DiovanTablets诺华56.65 -6.4% 5.57 -77.9%9 甘精胰岛素注射剂（降血糖药）Lantus Vials 赛诺菲-安万特54.53 17% 8.21 -71%10 伊马替尼胶囊(抗肿瘤药) GleevecCapsules诺华46.59 9.2% 4.15 -67.7%11 奥氮平片（抗精神病药）ZyprexaTablets礼来46.22 -8% 2.94 -88.2%12 吡格列酮片（降血糖药）ActosTablets武田制药41.33 -5.6% 7.04 -79.7%13 门冬胰岛素注射液NovoRapid Novo 39.40 715.3% - -14 雷珠单抗注射剂(抗黄斑变性药） Lucentis诺华/ Genentech 37.91 26.7% 4.16 -70.3%15普瑞巴林胶囊 （抗痉挛药） Lyrica Capsules 辉瑞36.93 20.6% 3.64 -74.4%16醋酸格拉替默注射剂（多发性硬化治疗药）Copaxone InjectionTeva 制药/赛诺菲-安万特36.00 8.6% 27.93 22.1%17 复方依法韦仑/恩曲他滨/替诺福韦酯片 （抗病毒药） AtriplaTablets Gilead 科学32.2510.2%4.63 -75.7%18来那度胺胶囊 (抗肿瘤药) Revlimid Capsules Celgene32.08 30.1% - 0%19 依诺肝素 (抗血栓药)Lovenox 赛诺菲29.40 -21.1% 1.59 -91.7%20 复方恩曲他滨/替诺福韦酯片（抗病毒药） TruvadaTablets Gilead 科学28.75 8.5% 3.20 -75.6%21阿立哌唑片 （抗精神病药） Abilify Tablets 百时美施贵宝/大冢制药 27.58 7.5% 4.60 -76.5%22培美曲塞 (抗肿瘤药) Alimta礼来24.61 11.4% 2.33 -75.7%23 奥美沙坦 （抗高血压药）Olmetec 第一三共23.45 267.6% 2.07 -13.7%24醋酸亮丙瑞林储库型控释注射剂 （抗肿瘤药）Lupron Depot 7.5 mg 雅培/武田制药/ Orion 23.38 21.8% 1.39 -71.2%25他克莫司胶囊 （免疫抑制药） Prograf Capsules Astellas 制药20.23 362% - 0%26美金刚片 (抗震颤麻痹药） Namenda Tablets H Lundbeck A/S /Forest 19.00 364.5% 3.29 -73.4%27肉毒(杆菌)毒素 （生物制品）Botox InjectionAllergan18.39 29.7% - 0%28 波生坦片（抗高血压药）TracleerTabletsActelion17.22 9.5% - 0%29 聚乙二醇化干扰素α-2a 注射剂(抗丙型肝炎药) PEGASYSInjection罗氏16.43 3.9% 3.92 4.8%30 阿扎那韦胶囊（抗病毒药）ReyatazCapsules百时美施贵宝15.69 6.1% 1.81 -76%31 依他凝血素α(凝血因子类药) NovoSeven Novo Nordisk15.60 8.9% - 0%32 卡培他滨片(抗肿瘤药) XelodaTablets中外制药/罗氏15.47 12.9% 1.32 -74%33 白喉、破伤风类毒类及无细胞百日咳吸附疫苗（生物制品）Daptacel 赛诺菲-安万特14.97 14.5% - 0%34 奥沙利铂注射剂(抗肿瘤药) Eloxatin 赛诺菲-安万特/益力多14.91 163% 3.47 51.8%35 唑来膦酸注射剂(抗骨质疏松药) ZometaInjection诺华14.87 -1.6% 1.49 -79.3%36 依法韦仑胶囊（抗病毒药）SustivaCapsules百时美施贵宝14.85 8.6% 2.15 -75.6%37 甲磺酸氨氯地平片（抗高血压药）NorvascTablets辉瑞14.45 292.7% 0.09 -72.7%38 醋酸奥曲肽微球缓释注射剂 (肢端肥大症治疗药) SandostatinLAR DepotGroup诺华14.43 11.8% 5.74 12.3%39地特胰岛素（降血糖药）LevemirFlexPen Group诺和诺德14.36 17% - 0%40 厄洛替尼（抗肿瘤药）TarcevaTablets罗氏/Genentech/中外制药/Astellas14.30 12.3% 1.27 -74.8%41 左乙拉西坦口服液（益智药）Keppra OralSolutionUCB制药13.45 7.5% 1.83 -50.5%42 多西他赛（抗肿瘤药）Taxotere 赛诺菲-安万特30.35 4.3% 11.52 8.6%43 复方甲磺酸氨氯地平/缬沙坦片（抗高血压药）ExforgeGroup诺华12.09 33.7% 0.74 -73.9%44 度他雄胺（5-α还原酶抑制药）Avodart 葛兰素史克12.02 23.5% 1.22 -76.5%45 恩替卡韦片（抗病毒药）BaracludeTabletsGroup百时美施贵宝11.96 28.5% 0.48 -73.2%46 琥珀酸索利那新片（膀胱过度活动症治疗药）VESIcareTabletsAstellas制药/葛兰素史克11.72. 18.5% - 0%47 流感病毒疫苗预填充注射剂FluzonePrefilledSyringes赛诺菲-安万特11.50 -33.2% 6.063571.3%48 利拉鲁肽（降血糖药）Victoza 诺和诺德11.20 171% - 0%49 吸附无细胞百日咳、白喉、破伤风联合疫苗InfanrixVaccineGroup葛兰素史克11.08 2.4% 0.64 -71.5%50 卡巴拉汀(血管性痴呆治疗药) ExelonCapsules Group诺华/小野制药10.67 6.4% 0.90 -76.3%51 复方阿莫西林/克拉维酸钾咀嚼片（抗生素）AugmentinChewableTablet Group葛兰素史克10.29 6.5% 0.48 -71.6%52 复方阿巴卡韦/拉米夫定片（抗病毒药）EPZICOMTablets葛兰素史克9.91 15.5% 0.82 -74.7%53 恩他卡朋片（帕金森病治疗药）ComtessTabletsGroup诺华/小野9.85 6.3% 0.52 -77.5%54 硫酸沙丁胺醇氢氟烷气雾剂(平喘药) VentolinAccuhalerGroup葛兰素史克9.67 19.8% 0.90 -67.4%55 来曲唑片(抗肿瘤药) FemaraTablets诺华/ 中外制药9.56 -32.3% 1.69 -74%56 酮洛芬透皮贴片（消炎镇痛药）Mohrus TapeGroup久光制药9.56 -32.3% 1.69 -74%57 生长激素液体制剂笔形注射器NorditropinNordiFlexGroup诺和诺德9.43 10.1% - 0%58 阿巴西普(抗关节炎药) OrenciaGroup百时美施贵宝9.17 25.1% 1.38 -74.8%59 复方ω-3脂肪酸/维生素E软胶囊Omacor SoftCapsulesGroup葛兰素史克9.14 11.7% 2.03 -75.2%60环孢素自乳化释药系统软胶囊（免疫抑制剂）Neoral SoftGelatinCapsules Group诺华9.03 3.7% 0.17 -79.3%61 拉莫三嗪（抗癫痫药）Lamictal CDGroup葛兰素史克8.61 10.5% 0.85 -78.5%62 去铁斯若分散片（铁鳌合剂）ExjadeTablets forOralSuspension诺华8.50 11.5% 0.51 -80.7%63 宫颈癌疫苗CervarixGroup 葛兰素史克8.13 117.2% 0.02 -92%64 拉喹莫德胶囊（免疫调节剂）AllegraCapsules Group赛诺菲/Albany分子研究8.08 0.2% -1.35 -100.7%65 达沙替尼(抗肿瘤药) SprycelTablets百时美施贵宝8.03 39.4% 0.61 -67.6%66 伊班膦酸钠片(抗骨质疏松药) BonivaTabletsGroup罗氏/葛兰素史克7.95 -21.5% 3.58 -29.2%67 双氯芬酸钠控释片（消炎镇痛药）Voltaren XRTabletsGroup诺华7.94 0.3% 0.01 0%68 艾库珠单抗Soliris Alexion制药7.83 566.2% - 0%（抗溶血药）69 美色拉嗪片(消炎药)AsacolTablets协和发酵麒麟/WarnerChilcott7.43 4% - -100%70 达托霉素(抗生素) Cubicin Cubist制药7.36 358.3% 1.86 -68.9%71 尼罗替尼(抗肿瘤药) Tasigna 诺华7.16 79.4% 2.55 90.3%72 阿扎胞苷(抗肿瘤药) Vidaza Celgene7.05 32.3% - 0%73 帕罗西汀口服混悬剂(抗抑郁药) PAXIL OralSuspensionGroup葛兰素史克6.99 -0.7% 0.02 0%74 左吡坦片（催眠药）AmbienTablets 赛诺菲/Astellas制药6.82 -37.3% 0.30 -94.9%75 维达利停(抗糖尿病药) Galvus Group 诺华6.77 73.1% - 0%76 依维莫司冠脉涂药支架系统XIENCE VGroup波士顿科学6.55 -19.1% 1.07 -79.7%77 吸附破伤风、减毒白喉类毒素及非細胞型百日咳混合疫苗 ADACELVaccine赛诺菲6.48 8.6% - 0%78 利马前列素片5 µg（抗凝血药）OPALMONTablets 5 µg小野制药/大日本住友制药6.41 -9.6% - 0%79 伊米苷酶(戈谢病治疗药) Cerezyme Genzyme6.14 -14.7% - 0%80 一年1次的唑来膦酸输液(骨质疏松症治疗药)Reclast 诺华 6.13 5.9% 3.86 -1.8%81 0.03%比马前列素滴眼液（抗青光眼药）LumiganOphthalmicSolution,0.03% GroupAllergan6’13 16.2% - 0%82 格列美脲片(降血糖药) AmarylTablets赛诺菲6.09 -4.1% 1.42 -82.2%83 脑膜炎球菌疫苗Menactra赛诺菲 5.95 2.7% - 0%84 司维拉姆片（磷酸盐结合剂）RenagelTabletsGroup中外制药/Genzyme 5.78 -17% - -100%85 肺炎球菌疫苗SynflorixVial Group 葛兰素史克5.64 64.9% - 0%86 阿利克仑(Aliskiren，抗高血压药) TekturnaGroup诺华5.57 27.2% 0.57 -72.5%87 哌甲酯缓释片（注意力不集中伴多动症治疗药）Ritalin SRTabletsGroup诺华/伊兰5.50 18.5% 0.99 -70.8%88 伐昔洛韦囊片（抗病毒药）ValtrexCaplets葛兰素史克5.45 -33.7% 0.35 -90.9%89 克拉霉素缓释片（抗生素）Biaxin XLTablets雅培5.42 4% - 0%90 帕尼突单抗(抗肿瘤药) Vectibix Amgen/武田制药5.29 47.9% 0.31 -73%91 麦考酚酸缓释片(免疫抑制剂) Myfortic 诺华5.18 16.7% 0.45 -72.4%92 复方拉米夫定/齐多夫定片（抗病毒药）CombivirTablets葛兰素史克5.18 -7.7% 0.48 -78.2%93 法莫替丁口溶片（组胺H2受体拮抗剂）Gaster DTabletsGroupAstellas制药 4.97 1.8% - 0%94 芬戈莫德(多发性硬化症药物) Gilenya 诺华4.94 12250% 3.83 2846.2%95 比伐卢定(抗凝血药) Angiomax 医药4.84 14.7% 1.05 -74.5%96 预防轮状病毒感染Rotarix Celldex治疗 4.82 377.3% 0.43 -62%的疫苗Vaccine97 沙格列汀（降血糖药）OnglyzaGroup百时美施贵宝4.73 199.4% 0.57 -52.1%98 吉西他滨注射剂(抗肿瘤药) Gemzar 礼来4.52 -60.7% 0.59 -91.8%99 磺达肝素(抗凝药) Arixtrainjection葛兰素史克4.44 -4.6% 0,71 -74.1%100 依维莫司(抗肿瘤药) Afinitor诺华 4.43 82.3% 0.49 58.1%。
2020年全球销售额top200的上市药物及结构美国Arizona大学的Jon Njardarson课题组发布了他们整理的2020年全球销售额top 200的上市药物及结构。
具体的pdf可以从这个网站下载：/content/top-pharmaceuticals-poster。
从网站查阅可发现，从2006年开始，该课题组就整理每年全球销售额top 200的上市药物及结构，并制作成poster供大众免费下载，以帮助公众了解化学尤其是有机化学在新药研发中发挥的重要作用。
图1. 2020年全球销售额top 200的上市药物及结构。
poster由Jon Njardarson课题组制作，生物药的image来自Pharmacodia公司，2020年销售数据来自DrugT opics & Pharmacompass top 200药物治疗的疾病涵盖肿瘤、免疫、糖尿病和心血管疾病等。
销量最高（209.47亿美元）的是治疗类风湿性关节炎、强直性脊柱炎、银屑病和克罗恩病等炎症和自身免疫性疾病的药物阿达木单抗（Humira，修美乐）。
Humira的靶点为肿瘤坏死因子-α（TNF-α），是通过噬菌体展示技术（该技术的发明人获得了2018年的诺贝尔化学奖）发现的全人源单克隆抗体。
销量排名最后（7.32亿美元）的是用于治疗低磷酸酯酶症（一种罕见的代谢疾病）的Strensiq，它是由两条肽链组成的糖蛋白。
参考文献：Nicholas A. McGrath, Matthew Brichacek, and Jon T. Njardarson "A Graphical Journey of Innovative Organic Architectures That Have Improved Our Lives". J. Chem. Ed. 2010, 87, 1348。
药品名称2001年4季度2002年1季度2002年2季度2002年3季度MAT1左旋氧氟沙星57,154,63761,384,95166,836,51480,002,754265,378,856 2人白蛋白51,178,78463,312,68762,877,68473,091,052250,460,207 3头孢曲松58,853,70661,267,71859,678,69463,641,582243,441,700 4头孢呋辛46,303,50456,012,15055,127,26465,058,148222,501,066 5舒巴坦钠/头孢哌酮钠43,341,66655,234,19252,815,22464,704,587216,095,669 6头孢他啶29,314,53739,568,21445,501,85958,448,878172,833,488 7胸腺肽28,412,60834,772,46559,314,47848,067,386170,566,937 8葡萄糖36,577,28539,020,56837,062,50641,743,866154,404,225 9环孢菌素36,851,76933,802,55440,054,26438,103,229148,811,816 10氯化钠31,837,43834,788,07435,927,06542,191,640144,744,217 11奥美拉唑32,541,68135,950,88034,920,88137,429,465140,842,907 12脂肪乳28,442,74532,571,52733,516,52837,216,566131,747,366 13阿奇霉素28,723,01630,566,51028,672,89637,114,242125,076,664 14紫杉醇24,007,44028,901,56734,020,53434,714,889121,644,430 15重组人粒细胞集落刺激因子(大肠杆菌)25,296,60024,731,76529,698,37939,396,501119,123,245 16头孢噻肟钠33,556,58629,158,36324,437,08429,167,383116,319,416 17阿莫西林/克拉维酸23,069,67624,868,76826,897,02225,712,086100,547,552 18克林霉素18,183,33625,000,72426,338,32729,281,13498,803,521 19亚胺培南/西司他丁19,552,86426,876,70024,944,33026,831,37798,205,271 20麦考酚酸酯22,237,22726,443,59118,630,87724,883,15292,194,847 21头孢克洛21,490,84524,426,84621,702,80324,156,61891,777,112 22头孢环己烯25,894,83322,982,54318,892,75821,548,17189,318,305 23单硝酸异山梨酯23,642,01223,109,00121,279,36420,802,78588,833,162 24阿卡波糖18,590,18420,395,85524,606,77623,342,26986,935,084 25二磷酸果糖19,578,51319,326,45921,986,21825,266,78686,157,976 26拉米夫定18,666,27219,395,45819,309,52924,951,81482,323,073 27舒巴坦/氨苄西林17,348,83019,241,12921,602,84724,025,06882,217,874 28氨氯地平18,551,35919,945,03719,430,13821,174,00979,100,543 29人血丙种球蛋白15,071,34418,307,93219,581,66524,584,18977,545,130 30银杏叶制剂16,651,49617,792,95419,603,41923,263,99977,311,868 31头孢哌酮12,052,85723,694,92516,637,93420,494,24172,879,957 32参麦15,344,42515,375,91618,565,46622,068,69171,354,498 33阿莫西林19,861,66018,920,15915,177,90017,023,62270,983,341 34碘苯六醇14,719,16317,138,42519,595,77719,014,50770,467,872 35康莱特16,453,19117,700,79518,831,56117,224,60170,210,148 36氟康唑16,323,74518,403,49715,686,78719,390,80969,804,838 37氨溴索15,474,91619,775,16315,637,13518,356,71569,243,929 38表柔比星14,042,99317,714,65916,409,98417,708,58065,876,216 39前列地尔12,932,69219,906,95714,018,47018,692,42965,550,548 40三七15,164,73314,084,81817,955,49117,683,09664,888,138 41谷胱甘肽10,840,38714,116,46417,383,73022,517,13664,857,717 42干扰素15,120,10714,102,75116,358,84518,682,69164,264,394 43非那甾胺15,588,65815,742,75215,328,67817,126,83963,786,927 44昂丹司琼15,377,64616,474,70414,599,96216,353,01262,805,324 45辛伐他汀14,195,05414,546,21616,388,28715,806,33660,935,893 46硝苯地平13,283,40615,407,66916,690,79115,138,18360,520,049 47奥曲肽14,573,36813,756,93614,846,61917,168,82660,345,749 48单组分胰岛素12,181,73913,449,06014,815,89616,763,46557,210,160 49多种维生素13,218,55110,820,73312,934,29219,251,31956,224,895 50碘普罗胺13,276,33414,854,83614,058,64013,137,30355,327,113 51异丙酚11,028,79510,048,85019,064,71314,852,36954,994,727 52尼莫地平13,379,16612,598,32013,593,31714,244,59653,815,399 53生长抑素10,160,11313,044,70014,889,86814,642,94252,737,623 54格拉司琼7,800,6916,929,70726,766,61510,581,70652,078,719 55纳络酮11,822,41416,306,35113,174,85710,501,40751,805,029 56葛根素13,485,38912,832,73313,055,47412,116,46951,490,065 57二甲双胍14,893,86512,502,76612,165,28210,921,76350,483,676 58甲酰四氢叶酸钙11,922,05312,812,71912,927,86611,937,71649,600,354 59醒脑静8,234,07512,410,70912,111,29716,224,95348,981,034 60依泊汀α11,613,95811,129,38011,330,73614,055,80048,129,874 61法莫替丁10,694,16411,703,55812,393,43813,261,92148,053,081 62奥沙利铂8,031,18511,110,41112,275,50315,621,14847,038,247 63氟西汀10,602,19911,172,20312,530,10412,554,56846,859,074 64三磷酸胞苷7,683,37310,398,75311,525,90917,086,12146,694,156 65环丙沙星12,982,4189,717,3809,970,46712,981,94245,652,207 66贝那普利11,320,29511,265,64811,332,49411,596,86445,515,30167双氯芬酸12,620,2759,196,44411,114,19911,771,78144,702,699 68钴宾酰胺9,193,5059,941,32912,418,50112,550,52544,103,860 69硝酸异山梨酯11,551,00312,037,31712,154,0948,094,13343,836,547 70葡萄糖氯化钠9,843,4419,174,5289,802,33213,672,57642,492,877 71异长春花碱8,763,86210,008,92511,675,20811,741,86642,189,861 72凡命9,780,98710,618,08710,533,53610,544,59641,477,206 73罗红霉素10,471,20512,155,6948,640,8909,629,98240,897,771 74氧氟沙星10,298,2769,459,1359,896,25710,805,00040,458,668 75复方丹参8,862,7399,646,38310,645,89210,943,12240,098,136 76复方氨基酸8,874,8959,338,47310,662,18310,656,82939,532,380 77头孢吡肟9,464,7639,691,4289,072,66910,924,20939,153,069 78灯盏花6,474,7718,613,18210,671,09712,638,98438,398,034 79奈替米星9,515,07710,436,1407,703,8549,646,83837,301,909 80吡拉西坦17,651,8108,980,4337,588,3212,573,37436,793,938 81西咪替丁9,098,0719,257,7868,592,8089,725,02336,673,688 82格列齐特8,682,3148,945,6298,610,7209,531,73535,770,398 83克拉霉素8,241,2079,911,3178,746,8818,795,82635,695,231 84门冬氨酸钾镁8,306,8297,690,3319,397,7659,948,27635,343,201 85肝得健8,444,6767,427,5947,819,88210,763,50734,455,659 86硫普罗宁6,283,2867,498,1249,543,46410,899,02834,223,902 87他克莫司14,454,6366,461,6766,197,8076,681,29233,795,411 88香菇多糖7,120,8917,256,4868,510,84110,888,44833,776,666 89低分子肝素钙7,700,0058,677,7538,881,6858,384,84033,644,283 90非洛地平7,479,6258,900,2908,243,2028,243,62232,866,739 91氯沙坦钾7,171,5188,223,2458,618,2738,432,91732,445,953 92肾灵8,126,8077,521,3388,313,0548,420,72732,381,926 93维生素E烟酸酯8,694,6887,714,7428,579,2307,113,45332,102,113 94福辛普利7,584,3458,007,7868,331,7908,116,10132,040,022 95吉西他汀5,161,5816,050,0978,559,63812,064,62131,835,937 96扑热息痛9,589,1458,581,4376,089,2577,442,39631,702,235 97格列吡嗪8,122,4568,134,4607,875,5237,424,72131,557,160 98双歧三联活菌8,586,2976,951,8897,875,6108,121,20731,535,003 99万古霉素6,167,4277,730,3558,005,3939,259,41531,162,590 100吡柔比星7,184,2806,960,9898,154,7938,749,52531,049,587 101来格司亭6,042,8807,311,2358,407,4648,751,81230,513,391 102白细胞介素-25,161,3027,412,3028,400,1219,087,59930,061,324 103腹膜透析液6,702,3297,979,4957,300,6938,078,17930,060,696 104丁咯地尔6,706,8906,270,8228,157,5488,866,61930,001,879 105立止血6,239,0906,596,6148,647,2528,342,95729,825,913 106氟罗沙星6,582,0177,139,1007,567,6448,413,01529,701,776 107羟基喜树碱4,482,0086,984,7899,882,2618,333,74829,682,806 108克林霉素磷酸酯3,075,1716,917,6017,732,07511,611,28529,336,132 109头孢羟氨苄6,344,4516,869,4177,137,2098,821,38829,172,465 110二氢麦角碱5,969,1068,153,0717,715,4287,247,27129,084,876 111核糖核酸4,174,1565,648,4678,476,47310,353,95628,653,052 112头孢唑肟2,609,1976,940,0708,054,62210,142,61827,746,507 113脑组织注射液10,690,6255,842,3725,908,5745,304,35227,745,923 114哌拉西林/他佐巴坦钠3,513,1905,165,0266,706,55711,922,45527,307,228 115依替米星3,500,5545,765,6097,304,52210,283,40226,854,087 116坦索罗辛5,511,5445,547,7297,541,5867,940,77026,541,629 117甲基强的松龙琥珀酸钠5,254,4276,515,9076,657,6827,769,92026,197,936 118洛美沙星5,772,8426,531,0776,153,1827,689,24526,146,346 119去甲万古霉素5,136,8756,562,3757,099,8007,329,09326,128,143 120羟乙基淀粉4,894,9735,373,8577,225,3528,407,39325,901,575 121更昔洛韦4,759,4125,765,8555,697,0479,662,26625,884,580 122癸酰乙醛5,136,0337,213,0105,792,5587,581,85825,723,459 123脑活素6,301,4005,918,4067,079,1066,282,04325,580,955 124腺苷蛋氨酸5,617,2225,718,2876,279,8367,904,71725,520,062 125阿米三嗪/罗巴新5,835,5316,103,2846,881,4556,582,21725,402,487 126格列喹酮6,838,6625,750,4006,620,4896,181,20425,390,755 127异氟烷5,467,6685,059,6376,208,0258,537,04025,272,370 128西替利嗪6,247,3735,318,8696,559,7137,145,28425,271,239 129钙尔奇D7,150,6595,802,8306,073,7116,108,04925,135,249 130头孢曲松/舒巴坦3,271,7325,689,4649,317,2266,783,51425,061,936 131蚓激酶5,552,8855,566,9987,498,2636,427,10925,045,255 132帕米膦酸二钠5,207,3455,400,9186,536,2927,550,58424,695,139 133甘草酸二铵5,778,3405,242,2536,180,7127,293,62624,494,931 134血活素6,901,4526,247,7775,842,1735,115,60924,107,011135七叶皂甙钠6,830,8145,290,5685,454,4945,907,18223,483,058 136头孢噻肟钠/舒巴坦钠4,520,3824,866,3385,919,4888,119,24523,425,453 137骨化三醇5,229,0515,961,2216,511,4795,577,68123,279,432 138神经节甙酯2,457,8964,811,6037,239,7758,694,67623,203,950 139甘油果糖5,107,2075,328,0855,839,6616,306,88122,581,834 140美托洛尔5,191,8626,026,8865,511,2055,448,82522,178,778 141胸腺五肽4,210,9446,021,8465,248,9826,601,86422,083,636 142替硝唑6,129,7044,999,6505,476,8935,455,20522,061,452 143米力农5,233,3436,197,8155,262,2275,250,22121,943,606 144多潘立酮5,668,6655,553,6755,693,4194,945,07321,860,832 145甲硝唑4,685,8665,019,4985,573,1666,474,52021,753,050 146氯雷他定5,039,4514,947,9395,649,4206,076,98721,713,797 147抑肽酶4,750,4854,537,7775,722,9876,694,15721,705,406 148维库溴铵6,607,6154,610,5345,115,9755,076,83821,410,962 149伊曲康唑4,375,0613,840,7775,659,9197,351,81721,227,574 150氯苄吡啶5,280,2545,498,3295,257,4855,002,39921,038,467 151曲马多5,085,4304,717,8315,555,2675,639,56020,998,088 152利培酮3,685,7795,240,2086,706,2055,147,76220,779,954 153a-甘露聚糖肽3,279,8384,858,8576,131,7396,478,86420,749,298 154胰岛素5,006,8834,470,6115,327,2055,888,05620,692,755 155头孢唑啉钠4,189,1095,856,8444,851,1225,603,67920,500,754 156乌拉地尔4,893,4234,879,6515,407,8845,254,94620,435,904 157卡托普利5,534,0305,441,6674,632,5984,826,23520,434,530 158降钙素4,759,0574,471,1445,869,5455,172,65020,272,396 159促卵泡成熟素6,238,9453,407,7597,555,1333,061,80520,263,642 160司氟沙星4,018,0405,101,7435,191,1785,945,39220,256,353 161依诺沙星3,345,3224,470,2925,585,4766,811,73220,212,822 162卡培他滨4,641,5954,040,4074,406,9646,865,85119,954,817 163丹参4,070,0744,588,8936,329,3184,675,34819,663,633 164美洛西林5,511,6054,199,6594,034,0905,732,90219,478,256 165榄香烯4,061,5894,530,4645,135,7925,396,93419,124,779 166西拉普利4,291,9014,908,4904,922,8974,902,34519,025,633 167特拉唑嗪4,423,7914,945,8194,266,3974,982,76218,618,769 168透明质酸钠3,543,2534,088,7195,426,4285,437,08718,495,487 169维生素C3,980,5004,400,6534,714,9575,368,02418,464,134 170舍尼通4,270,7944,412,8904,344,0085,203,00618,230,698 171胰激肽释放酶4,443,9314,431,9834,555,4384,637,89718,069,249 172乌司他丁3,573,7303,458,4104,324,0296,664,05218,020,221 173茴三硫4,607,0784,064,7284,907,3844,390,62717,969,817 174依泊汀β3,897,9174,953,5155,129,4043,772,59717,753,433 175青霉素G钠3,942,4124,659,2704,222,5574,879,53617,703,775 176泮托拉唑2,460,3943,248,5765,058,4906,617,83517,385,295 177丙戊酸钠3,746,1643,805,3414,252,8355,463,48517,267,825 178碳酸铝镁4,427,9994,395,0823,682,3564,637,63517,143,072 179脑多肽4,657,9503,951,8003,641,1864,790,28817,041,224 180多西他赛4,133,8563,641,9704,234,6734,992,67717,003,176 181特比萘芬3,445,6212,633,6604,215,4256,670,54016,965,246 182生长激素3,744,8893,721,4784,308,9435,164,10616,939,416 183琥珀酸明胶4,353,4963,653,4664,314,8944,400,29816,722,154 184非诺贝特4,792,9333,533,8833,751,2254,559,72316,637,764 185利巴韦林5,186,3254,639,3192,859,0603,929,62716,614,331 186重组人促卵泡成熟激素2,290,1431,308,2785,471,9877,417,62516,488,033 187哌拉西林钠/舒巴坦钠3,479,0424,319,8874,138,4614,390,54616,327,936 188乳果糖3,764,3363,811,1654,215,9184,444,94016,236,359 189比索洛尔3,733,2693,926,3814,228,4574,309,90416,198,011 190三氟噻吨-四甲蒽丙胺3,418,8193,792,7374,134,9054,656,70716,003,168 191芬太尼3,094,9944,228,6603,762,9934,770,03715,856,684 192异环磷酰胺4,153,4583,294,1704,000,5404,307,84815,756,016 193复方乳酸钠林格3,893,4923,671,9303,890,8014,197,24915,653,472 194磷霉素3,314,0404,322,0093,748,1404,187,38215,571,571 195脑细胞生长肽3,931,3203,495,1033,870,5634,270,44015,567,426 196帕罗西汀3,779,6013,352,0003,917,9534,377,12315,426,677 197脑蛋白水解物1,883,6593,468,4714,969,5495,032,24715,353,926 198巴曲酶2,820,0733,537,5914,015,5634,698,25815,071,485 199多巴丝肼3,557,7393,634,1603,724,2354,123,26215,039,396 200拉氧头孢1,050,9792,308,3874,988,1186,672,27015,019,754 201吗啡2,538,1993,697,4694,712,7233,970,72714,919,118 202布洛芬3,742,5333,370,2483,861,6213,885,12614,859,528203华蟾素2,049,0803,080,4274,448,5985,277,31914,855,424 204头孢硫脒2,254,1043,696,0993,999,5544,854,16214,803,919 205美洛培南三水物2,846,6293,613,4263,344,6324,927,42114,732,108 206美洛昔康2,795,6282,884,1574,277,0344,341,96414,298,783 207卡尼汀2,947,9922,610,1193,803,7674,866,47714,228,355 208地尔硫卓3,425,1043,752,0663,517,0273,487,08014,181,277 209阿法骨化醇3,067,4623,689,7023,473,4743,917,47714,148,115 210甘露醇3,973,5273,208,7083,090,9823,809,53114,082,748 211乌体林斯4,665,5963,528,1822,590,9453,277,72614,062,449 212奥扎格雷钠1,727,5243,592,4904,492,3414,131,94513,944,300 213依那普利3,261,7453,922,1633,332,7573,402,59113,919,256 214复方氯唑沙宗3,250,1302,847,3123,509,0423,975,48513,581,969 215凝血酶3,215,2383,768,9323,076,5203,508,08413,568,774 216硝酸咪康唑3,321,2702,293,3033,306,7734,501,88413,423,230 217头孢氨苄3,199,3603,550,0993,305,5263,285,97013,340,955 218钆喷酸葡胺3,490,2242,609,0253,088,1724,116,81513,304,236 219转移因子3,856,9832,962,2332,811,5733,550,94313,181,732 220双八面体蒙脱石3,394,6222,756,9862,872,6864,121,26813,145,562 221倍他司汀4,163,7672,911,8513,032,9762,865,67312,974,267 222碘帕醇3,303,1012,900,4943,548,7243,111,52412,863,843 223心血康3,545,1653,213,2263,115,9842,880,26512,754,640 224培哚普利2,799,7843,225,5233,555,0493,167,37112,747,727 225强力脉痔灵2,841,9592,766,4363,335,1293,759,06812,702,592 226环磷腺苷4,006,1123,480,5522,361,7082,729,27712,577,649 227去氧氟尿苷2,121,4453,368,1613,378,3093,688,49112,556,406 228穿心莲2,317,7013,843,6942,468,4723,916,56712,546,434 229兰索拉唑3,893,2973,055,6113,012,5162,572,35612,533,780 230莫拉司亭2,694,4133,283,5532,882,1413,667,06412,527,171 231托烷司琼2,533,6302,353,4683,750,6583,817,03512,454,791 232多抗甲素3,229,6592,884,8023,446,4542,888,24812,449,163 233氨基葡萄糖2,338,1772,720,1213,756,3043,571,10412,385,706 234氟桂利嗪3,304,6923,138,7083,021,1512,916,56112,381,112 235枸橼酸铋钾3,857,9312,807,3502,941,5732,732,13912,338,993 236伐昔洛韦3,152,9182,959,7602,937,8913,204,83212,255,401 237吲哒帕胺2,944,2563,196,7553,198,5212,861,65412,201,186 238阿洛西林3,258,9163,191,3702,632,3793,038,46212,121,127 239低分子肝素钠2,371,9643,178,1983,045,1793,321,22511,916,566 240妥布霉素2,209,2232,543,4572,753,8614,340,94311,847,484 241卡介菌多糖核酸2,353,1442,286,1522,853,2884,100,48911,593,073 242阿仑膦酸钠2,473,9422,674,7513,187,0563,197,21811,532,967 243妥布霉素/地塞米松2,577,4632,387,2103,347,5923,197,51511,509,780 244凝血酶原复合物2,437,2952,459,0352,808,3483,776,40511,481,083 245琥乙红霉素3,060,6803,136,7732,397,9212,629,03011,224,404 246神经妥乐平1,983,7362,632,3463,361,4323,223,10811,200,622 247枸橼酸西地那非2,085,2412,858,5223,018,8053,114,10111,076,669 248刺五加2,396,9942,539,4383,021,9933,069,34911,027,774 249益康唑2,341,3702,236,2082,999,6303,363,50010,940,708 250西利马林2,551,2072,323,4232,402,7263,507,13010,784,486 251N(2)-L-丙氨酸-L-谷氨酰胺1,853,2811,744,0072,927,9844,193,12510,718,397 252培氟沙星1,494,4862,401,7643,631,7833,183,83910,711,872 253丁酸氢化可的松2,308,6362,345,2523,146,6212,887,67910,688,188 254利血生2,586,3492,371,4082,665,6072,962,21110,585,575 255能全素2,172,3262,370,7542,776,9123,225,00410,544,996 256替卡西林钠/克拉维酸钾2,651,3872,789,8162,183,5642,901,68710,526,454 257促肝细胞生长素2,701,0662,291,7842,649,5532,869,71410,512,117 258氯化钾1,766,2792,321,8393,614,3392,716,44510,418,902 259阿昔洛韦1,998,4622,184,3743,376,4952,607,08410,166,415 260多维元素3,000,0322,383,1392,140,6452,625,24910,149,065 261长春地辛2,455,7552,254,4432,482,6892,937,55810,130,445 262依诺肝素钠1,853,4752,280,3782,253,8753,726,75210,114,480 263氨氯青霉素钠2,585,7422,607,3392,740,9172,097,25710,031,255 264氟氧头孢2,005,4802,139,7881,727,0234,124,2729,996,563 265布地奈德2,516,4242,192,0892,510,1532,730,6179,949,283 266胞磷胆碱2,322,9182,381,4302,375,0152,783,4849,862,847 267倍氯米松双丙酸酯2,889,7662,237,0342,009,6042,644,3419,780,745 268氨苄西林2,451,8862,761,2241,993,7942,330,8969,537,800 269维生素E2,593,4482,221,0052,208,9542,502,0989,525,505 270利妥昔单抗1,556,0921,299,9522,726,2093,908,4889,490,741271沙丁胺醇2,530,7012,435,0142,060,2732,326,0849,352,072 272尿激酶2,972,6272,610,9411,885,7691,738,7899,208,126 273w-3脂肪酸3,051,7582,226,9931,956,3131,941,5859,176,649 274强力稀化粘素1,841,5562,559,9252,380,7742,325,6289,107,883 275胺碘酮2,210,4012,132,1552,030,6972,719,8999,093,152 276顺铂2,621,3441,950,2222,105,8152,408,4439,085,824 277阿司匹林1,974,2802,122,0892,266,6952,701,0059,064,069 278氨甲环酸1,721,2662,108,4482,471,4232,716,7329,017,869 279氟尿嘧啶脱氧核苷1,859,8172,226,3112,425,0182,495,4429,006,588 280缬沙坦2,108,6841,942,1782,209,8802,731,2788,992,020 281阿特普酶2,049,2432,049,7062,316,0872,573,9068,988,942 282曲普瑞林1,692,5141,173,4182,871,4513,226,7678,964,150 283头孢米诺1,931,4912,265,0221,920,7992,809,9298,927,241 284清开灵2,089,8192,125,9822,081,8312,615,5768,913,208 285缓释钾1,897,1002,104,0442,180,3342,707,1658,888,643 286咪达唑仑1,944,1971,721,9372,556,1042,623,2888,845,526 287骨宁1,786,4312,267,0272,897,2171,872,2028,822,877 288托吡酯1,907,1471,999,6922,413,7912,482,4608,803,090 289头孢替唑钠1,453,2892,406,3822,415,7812,511,8938,787,345 290甲羟孕酮2,721,7232,007,8541,729,0062,247,4518,706,034 291肝素钠1,961,1052,296,3652,246,0152,201,4868,704,971 292降压0号2,231,9322,172,4802,257,0861,999,5638,661,061 293高聚金葡素1,403,9812,003,1861,931,7483,293,7318,632,646 294普伐他汀钠2,060,0721,978,6872,057,3522,472,6458,568,756 295替勃龙2,207,4232,215,6752,217,8331,883,9758,524,906 296磷酸肌酸1,930,2682,130,7532,045,0662,385,0918,491,178 297芦氟沙星1,841,6151,962,4202,019,5462,614,1918,437,772 298氨力农2,137,6382,419,3532,050,3451,802,3778,409,713 299聚乙烯吡咯酮-碘1,875,9622,071,2602,162,2622,258,7838,368,267 300氟他胺2,009,9842,116,8281,776,7612,434,7218,338,294 301溴隐亭2,135,8781,838,9672,067,6582,294,3248,336,827 302曲美他嗪1,618,5972,221,3902,081,7962,407,9828,329,765 303泛癸利酮2,285,2382,042,9251,979,2591,989,5248,296,946 304尿促性素1,787,6671,444,1262,560,8512,488,6588,281,302 305琥珀酸亚铁1,868,0181,569,9112,003,5122,812,8968,254,337 306阿糖胞苷1,747,8691,844,8002,084,4472,557,8448,234,960 307匹维溴铵1,774,3741,760,3962,231,8992,441,0228,207,691 308爱维治2,205,0212,248,6341,868,4691,879,1738,201,297 309卡铂2,252,4631,704,5922,001,4522,228,1478,186,654 310莫米松1,546,5981,696,8562,461,9442,440,6228,146,020 311西洛他唑1,837,3061,884,2952,022,5782,324,9348,069,113 312西沙必利2,302,4651,889,2932,010,4021,814,9668,017,126 313麦滋林-S1,680,5122,188,9452,094,9682,030,5677,994,992 314康脑灵1,867,6881,738,0911,999,3432,374,8067,979,928 315赖氨酸1,022,0101,351,3642,282,4773,316,8647,972,715 316云芝多糖1,395,1351,561,2722,581,0182,408,0607,945,485 317保肾康1,881,9681,961,6732,000,6902,093,2237,937,554 318尼麦角林1,928,7022,025,4541,712,5812,234,0597,900,796 319施普瑞1,616,9441,829,5672,202,2372,205,8737,854,621 320强力安喘通1,889,6562,317,2791,741,9351,897,7987,846,668 321复方甘草合剂2,064,8342,337,3291,698,1651,735,0837,835,411 322哌拉西林1,457,3461,785,8122,068,3702,504,3947,815,922 323双黄连1,864,1432,623,9671,432,7271,857,6847,778,521 324左甲状腺素钠1,855,8701,893,0321,945,5792,078,2157,772,696 325钙氨基酸螯合物1,964,8681,938,1621,715,7782,097,2127,716,020 326多酶1,547,1872,150,8171,664,2392,286,0507,648,293 327吉非贝齐1,996,5141,896,1502,026,5161,680,8567,600,036 328头孢地嗪1,037,7182,461,1821,516,9562,577,4527,593,308 329泛影葡胺1,760,8461,619,6072,220,7361,989,4587,590,647 330氯唑西林717,9391,872,0242,022,8502,888,2507,501,063 331他莫昔芬2,128,0041,580,0082,042,6091,717,1147,467,735 332包醛氧化淀粉1,190,7502,631,2431,274,6922,256,2437,352,928 333肝细胞水解物1,668,2081,556,6072,351,7841,774,4067,351,005 334平消胶囊1,464,9881,569,9872,009,8882,260,6507,305,513 335头孢克肟1,345,0521,769,4251,681,9222,487,6367,284,035 336复方莪术油1,795,3631,340,8652,062,1331,997,0027,195,363 337孕三烯酮1,674,6031,356,9651,738,8242,387,8547,158,246 338乌苯美司1,599,5711,429,3951,615,7312,473,4707,118,167339酪酸梭状芽胞杆菌1,656,9041,523,7301,959,5161,944,9397,085,089 340茶碱2,060,4702,167,6301,540,4971,196,2446,964,841 341利福霉素1,261,3541,517,1742,215,5491,966,9386,961,015 342塞来昔布980,6291,265,9832,031,3432,674,4916,952,446 343萘丁美酮2,170,0251,735,7641,713,6111,330,2506,949,650 344卡莫氟2,129,3251,583,4511,501,9651,709,4996,924,240 345抗Tac单抗255,8681,933,1422,008,4232,722,9936,920,426 346尼卡地平1,633,0991,929,4121,711,1301,620,7886,894,429 347核酪1,834,6441,983,9401,549,1901,522,4506,890,224 348莫沙必利1,265,8271,387,7291,845,8972,358,9896,858,442 349吡诺克辛钠1,630,3051,366,3351,781,2852,079,5056,857,430 350类肝素1,644,1591,513,4741,921,9071,744,3426,823,882 351尼群地平1,653,3461,880,4581,843,4661,443,2416,820,511 352含D3碳酸钙1,609,8031,245,1711,787,7522,170,0076,812,733 353心血通1,444,7321,818,2061,657,1461,873,1176,793,201 354重组牛碱性成纤维细胞生长因子(融合蛋白)1,473,4451,435,1471,786,5242,094,8666,789,982 355膦甲酸钠1,311,346843,2591,077,8173,489,7296,722,151 356地衣芽胞杆菌1,422,3541,330,9861,679,4842,277,2586,710,082 357雷尼替丁1,331,3311,696,1771,613,7192,039,4176,680,644 358氟伐他汀1,536,8421,547,8471,721,1231,838,8486,644,660 359甲氨喋呤1,480,9691,446,3781,688,3092,014,9636,630,619 360开塞露1,539,4241,619,2141,587,0901,856,5296,602,257 361苦参碱1,213,3441,431,4701,828,6982,108,8956,582,407 362宁心宝1,527,9411,594,3991,620,6741,793,5096,536,523 363卡马西平1,511,6631,532,5651,553,9231,936,6226,534,773 364瑞格列奈1,288,7861,388,6251,738,3812,043,5716,459,363 365罗哌卡因957,3231,147,1522,279,1782,039,3346,422,987 366交沙霉素1,950,0441,838,9421,304,0441,325,0066,418,036 367氟甲松龙938,1221,240,0961,646,3132,577,1956,401,726 368异丙托溴铵1,432,1621,675,8811,493,9751,767,7386,369,756 369亮丙瑞林1,616,3361,328,2191,662,6391,751,8446,359,038 370丙卡特罗1,506,5521,633,4551,816,2711,394,0106,350,288 371米诺环素1,395,5931,387,6121,748,9691,807,3446,339,518 372红色诺卡氏菌细胞壁骨架863,1541,671,6721,686,5242,117,4156,338,765 373去甲氧基柔红霉素1,393,7911,617,8091,443,6771,869,8136,325,090 374达卡巴嗪1,339,2731,345,6721,798,8821,818,2186,302,045 375丝裂霉素1,518,8081,312,1541,744,4651,724,8996,300,326 376奥氮平734,6231,014,5811,714,3802,795,9976,259,581 377碘佛醇141,6172,439,8101,661,6562,015,0686,258,151 378氨苄西林/氯唑西林1,397,8641,222,9421,532,4302,104,1566,257,392 379氨曲南1,529,9571,678,5531,698,7661,328,8616,236,137 380复方氯化钠1,575,1991,208,1931,479,4801,881,7996,144,671 381乳酸菌素1,405,2901,335,6401,584,0991,818,4266,143,455 382善存1,757,8651,324,1791,299,3531,738,7046,120,101 383罗格列酮1,018,2541,024,3851,656,3112,415,4396,114,389 384熊去氧胆酸897,832982,9571,385,8382,816,5956,083,222 385人参多糖1,197,694962,9051,266,3072,618,8206,045,726 386维胺酯730,1731,514,2651,559,5892,205,2046,009,231 387苦参素400,962886,0821,566,3223,155,6556,009,021 388硫酸氯吡格雷547,717835,2141,850,1342,768,6166,001,681 389柳氮磺胺吡啶1,284,6711,399,9731,603,2891,669,5305,957,463 390异帕米星432,0371,208,8022,188,4712,070,9495,900,259 391米非司酮1,397,3321,462,6201,549,6511,488,1325,897,735 392米托蒽醌1,444,2741,695,2701,372,2241,370,4365,882,204 393艾司洛尔1,511,0611,010,5751,401,4721,875,4715,798,579 394依托泊甙1,762,5131,356,1761,250,8811,424,0825,793,652 395伏格列波糖1,492,8451,339,1181,314,6141,544,3545,690,931 396阿米卡星1,164,0431,385,8901,585,6331,537,1695,672,735 397硫唑嘌呤1,310,5941,102,1921,307,0181,926,8705,646,674 398阿托伐他汀钙640,467950,2771,731,8472,319,5305,642,121 399硝酸甘油1,319,9831,433,0711,565,6191,322,2985,640,971 400替尼泊甙1,230,7831,306,5211,545,0911,546,9785,629,373 401迪银片1,235,3232,161,0981,291,369934,2105,622,000 402文拉法辛1,549,660977,2671,348,5331,740,4605,615,920 403绒促性素1,098,711859,7471,719,1591,812,8495,490,466 404乙哌立松1,321,6571,127,4141,357,0891,653,3135,459,473 405曲克芦丁1,116,5271,291,8831,427,0971,551,7455,387,252 406A群链球菌冻干制剂1,237,2791,209,1171,560,4871,359,6305,366,513407卵磷脂络合碘1,605,165625,0061,261,6271,867,1255,358,923 408玻璃酸钠/氯霉素1,223,2431,133,6471,429,4351,549,1775,335,502 409九维他260,033331,1831,285,0393,421,0155,297,270 410莫匹罗星1,254,6261,084,2511,207,4381,746,1205,292,435 411异维A酸1,381,7981,069,4441,289,1001,547,8255,288,167 412吉法酯1,504,4091,336,1331,258,5741,183,2255,282,341 413二丙酸倍他米松及倍他米松磷酸酯钠1,148,8421,157,1341,404,4771,570,4515,280,904 414达纳康1,139,996976,2731,357,6031,679,8435,153,715 415华法林钠1,158,7811,252,1221,244,1641,486,4845,141,551 416硫糖铝1,255,4481,300,8321,440,9521,141,4295,138,661 417口服复合氨基酸1,028,2701,325,4141,452,9811,316,8845,123,549 418精蛋白锌胰岛素845,1631,317,2791,377,0481,573,0705,112,560 419维生素AD1,310,5131,255,3031,175,6601,337,9375,079,413 420青霉素V1,318,5301,465,8501,094,8681,184,5805,063,828 421肝安1,395,4811,139,1551,209,4481,303,3735,047,457 422克霉唑1,520,4871,068,381973,3381,467,3305,029,536 423阿尼西坦1,536,5741,365,9071,126,580997,3715,026,432 424恩氟烷1,272,0891,205,6681,414,0261,114,4895,006,272 425拉西地平1,501,0001,301,530997,5421,166,4324,966,504 426罗非昔布952,9741,458,4891,347,5411,200,6764,959,680 427右旋糖酐-401,006,3431,420,8101,301,4741,226,1924,954,819 428胰酶1,163,7421,116,1801,291,5281,372,0294,943,479 429己酮可可碱1,801,5991,324,800993,331812,6034,932,333 430联苯苄唑1,126,424802,4911,496,2461,505,4534,930,614 431奥利司他1,201,8331,023,6871,100,3631,482,2984,808,181 432扶正冲剂453,919411,1163,930,6024,795,637 433肌苷1,017,8501,047,2301,088,0921,629,4474,782,619 434替加氟841,808818,7831,950,6281,166,7174,777,936 435小牛血去蛋白153,1011,389,4083,145,4244,687,933 436红霉素513,320935,6961,219,5182,017,7034,686,237 437去氨加压素1,240,9861,258,315977,3841,174,8644,651,549 438硝普钠1,176,5631,218,3401,272,709981,9394,649,551 439甲钴胺822,6481,215,8841,473,6841,088,0164,600,232 440多柔比星937,3241,360,6321,183,7891,082,1654,563,910 441比卡鲁胺93,9581,272,4541,901,0391,291,5414,558,992 442川芎嗪546,981943,3481,355,5581,708,5524,554,439 443尼美舒利1,304,366887,3351,172,6161,164,5924,528,909 444酮康唑1,221,5571,207,3291,010,9201,087,9344,527,740 445倍美力971,1471,152,7641,141,8581,260,4744,526,243 446地喹氯铵1,152,9301,084,2521,042,6991,234,2754,514,156 447头孢美唑278,902389,5191,025,1522,810,5484,504,121 448心先安805,2931,284,246914,9301,452,7884,457,257 449克拉维酸钾/阿莫西林843,5641,099,2491,542,742947,3054,432,860 450复方灵芝片991,492822,6731,243,8641,367,9814,426,010 451维拉帕米1,272,7571,203,242998,641935,7314,410,371 452利多卡因880,5261,047,6721,355,8891,121,1814,405,268 453氯美扎酮1,117,3901,003,3591,228,8161,048,5644,398,129 454聚甲酚磺醛984,159823,0531,271,2581,283,0034,361,473 455氯己定774,427937,7101,375,2761,264,9654,352,378 456来氟米特606,611877,1691,109,4281,754,9114,348,119 457厄贝沙坦102,5841,050,3371,372,9501,789,3324,315,203 458阿莫西林/舒巴坦钠119,495790,169664,9782,706,3274,280,969 459鸦胆子油727,240647,9621,092,8701,803,2764,271,348 460十一酸睾酮1,132,252975,948937,9241,215,4204,261,544 461泛昔洛韦1,119,410601,9751,176,6761,356,1794,254,240 462氯屈膦酸二钠619,4891,779,101495,9931,356,0084,250,591 463复方二氢麦角隐亭1,259,2031,100,8351,056,632829,4194,246,089 464去甲斑蟊素898,295929,3311,149,0551,253,0624,229,743 465氟马西尼669,985874,974818,7811,856,0654,219,805 466浓缩第八因子591,087750,5221,319,1571,545,2764,206,042 467吲哚美辛/氨基葡萄糖822,454793,0781,090,4121,477,0924,183,036 468脑复活923,291759,6731,244,0631,229,1914,156,218 469替考拉宁562,7161,632,8141,955,4004,150,930 470胆汁加五味子993,9151,001,7611,082,0721,063,8544,141,602 471唑吡坦917,688996,0941,078,1261,135,2214,127,129 472赖氨匹林807,3531,067,318890,3191,351,7874,116,777 473维生素B6809,288874,089983,4671,444,4244,111,268 474地塞米松769,429881,4131,064,1081,382,9894,097,939475乙型肝炎免疫球蛋白744,783797,707944,6411,567,6474,054,778 476复方甘草甜素194,741664,8321,253,6161,852,7003,965,889 477脂必妥915,711918,198861,1761,245,7333,940,818 478锌布颗粒1,066,1281,189,922804,667879,9383,940,655 479小蘖胺517,3671,117,4571,018,5551,286,4683,939,847 480平阳霉素816,615921,5751,190,979995,2993,924,468 481谷康泰灵1,148,436832,303998,198940,0093,918,946 482替普瑞酮911,400924,493832,5671,250,2193,918,679 483茵栀黄525,329973,3901,327,4991,090,4593,916,677 484乳杆菌制剂1,321,504704,602753,1041,124,0253,903,235 485依降钙素666,785857,0051,084,3101,293,5653,901,665 486安达美633,493757,3411,123,5431,379,2293,893,606 487人破伤风免疫球蛋白353,642695,0881,258,6241,583,2903,890,644 488左旋氨氯地平779,889787,775854,4791,452,5863,874,729 489特布他林1,125,5791,128,229761,846843,0763,858,730 490雷米普利848,888906,614944,4291,105,9293,805,860 491羟苯磺酸钙910,550861,3911,003,4711,003,1443,778,556 492托瑞米芬1,104,3131,342,7531,320,5873,767,653 493莫雷西嗪1,212,335753,810798,432998,6463,763,223 494卡维地洛742,892815,4621,000,8881,158,7973,718,039 495碳酸钙1,249,326920,659771,629760,4483,702,062 496舍曲林827,797834,066954,8501,084,0453,700,758 497托泊替康1,224,358765,773617,8691,064,9283,672,928 498维甲酸778,770734,557820,5061,314,0273,647,860 499阿莫西林/双氯西林850,151748,208981,1291,056,1063,635,594 500乙酰半胱氨酸1,116,885898,359840,252770,5403,626,036。
排名商品名通用名生产产商销售额（美元）1 立普妥Lipitor （阿托伐他汀钙）辉瑞$7,668,425,0002 波利维Plavix （氯吡格雷）百时美施贵宝/赛诺菲-安万特$6,771,208,0003 耐信Nexium （埃索美拉唑）阿斯利康$6,155,770,0004 安律凡Abilify （阿立哌唑）日本大冢制药OtsukaAmerica$5,194,026,0005 舒利迭AdvairDiskus 沙美特罗替卡松气雾剂葛兰素史克$4,636,975,0006 思瑞康Seroquel 富马酸喹硫平阿斯利康$4,636,757,0007 顺尔宁Singulair 孟鲁司特美国默克$4,592,876,0008 可定Crestor 瑞舒伐他汀阿斯利康$4,403,572,0009 欣百达Cymbalta 度洛西汀礼来$3,666,405,00010 修乐美Humira 阿达木单抗美国雅培$3,531,157,00011 恩利Enbrel 依那西普美国安进$3,506,883,00012 类克Remicade 英夫利昔单抗Centocor（强生子公司）$3,474,381,00013 艾可拓Actos 吡格列酮Takeda（日本武田制药）$3,437,722,00014 Neulasta 培非格司亭美国安进$3,316,498,00015 美罗华Rituxan 利妥昔单抗美国基因泰克$3,004,543,00016 再普乐Zyprexa 奥氮平礼来$2,964,582,00017 Copaxone 醋酸格拉替雷以色列梯瓦制药$2,955,597,00018 Lexapro 依地普伦美国森林实验室$2,926,431,00019 Oxycontin 奥施康定美国普渡制药purdue $2,880,324,00020 阿法依泊汀Epogen 促红细胞生成素美国安进$2,773,508,000排名商品名通用名生产企业21 Avastin 阿瓦斯汀美国基因泰克22 Atripla 依法韦恩茨/恩曲他滨/替诺福韦富马酸片复方制剂百时美施宝贵/吉利德科学公司23 思力华粉吸入剂SpirivaHandiHaler噻托溴铵勃林格殷格翰24 捷诺维Januvia 西列他汀默克25 Lantus 甘精胰岛素赛诺菲安万特26 特鲁瓦达Truvada 恩去他滨吉利德科学公司27 代文Diovan 缬沙坦诺华28 乐瑞卡Lyrica 普瑞巴林辉瑞29 西乐葆Celebrex 塞来昔布辉瑞30 Lucentis 兰尼单抗注射液美国基因泰克31 赫赛汀Herceptin 注射用曲妥珠单抗美国基因泰克32 复代文Diovan HCT 缬沙坦/氢氯噻嗪片诺华33 Avonex β干扰素美国百健艾迪34 兰德仕注射剂Lantus甘精胰岛素赛诺菲安万特Solostar35 格列卫Gleevec 甲磺酸伊马替尼诺华36 Nameda 盐酸美金刚美国森林实验室37 Enoxaparin Sodium 依诺肝素钠奥地利山德士制药38 卓尔定Geodon 齐拉西酮辉瑞39 艾泽庭Zetia 依泽替米贝默克/先灵葆雅40 卓佳Tricor 非诺贝特雅培41 Vyvanse 二甲磺酸赖右苯丙胺Shire制药42 舒倍生Suboxone 丁丙喏啡与纳洛酮复方利洁时43 Lidoderm 利多卡因日本株式会社远藤公司44 Procrit 阿法依泊汀杨森制药Janssen45 乐沙定Eloxatin 奥沙利铂赛诺菲安万特46 Niaspan 缓释烟酸片雅培47 不夜神Provigil 莫达非尼片梯瓦制药48 Aranesp 阿法达贝泊汀注射剂美国安进49 昂斯妥Androgel 睾酮凝胶雅培50 可必特Combivent 异丙托溴铵气雾剂德国勃林格殷格翰51 克赛Lovenox 依诺肝素钠赛诺菲安万特52 利比Lovenox 干扰素β-1a注射剂瑞士雪兰诺53 维力妥Vytorin 依折麦布/辛伐他汀复方默克/先灵葆雅54 内舒拿Nasone 糠酸莫米松鼻喷雾剂先灵葆雅55 万艾可ViagraSymbicort 枸橼酸西地那非片辉瑞56 信必可Symbicort 布地奈德福莫特罗阿斯利康富马酸喹硫平阿斯利康57 思瑞康缓释片SeroquelXR58 力比泰Alimta 注射用培美曲塞美国礼来59 诺和锐NovoLog 门冬胰岛素丹麦诺和诺德60 Lovaza omega-3脂肪酸乙酯胶囊葛兰素史克61 优泌乐Humalog 重组赖脯胰岛素美国礼来62 Adderall XR 苯丙胺盐混合物Shire制药63 优保津Neupogen 非格司亭美国安进64 Flovent HFA丙酸氟替卡松葛兰素史克65 Proair HFA 硫酸沙丁胺醇以色列锑瓦制药66 瑞艾妥Reyataz 硫酸阿扎那韦百时美施宝贵67 Aciphex 雷贝拉唑钠日本Eisai制药68 专注达Concerta 盐酸哌甲酯缓释片杨森制药Janssen69 Budesonide 布地奈德以色列锑瓦制药70 Levemir 注射用地特胰岛素诺和诺德71 Incivek 特拉瑞韦美国Vertex制药72 Varivax 水痘疫苗默克73 Prevnar-13 肺炎球菌13价联合疫苗辉瑞74 鲁尼斯塔Lunesta 艾斯佐匹克隆片美国Sunovion制药75 希爱力Cialis 他达拉非礼来76 Solody 盐酸米诺环素控释片美国Medicis（加拿大Valeant收购）77 NovoLog Flexpen 胰岛素预填充注射笔诺和诺德78 艾特生Isentress 拉替拉韦默克79 Levaquin 左氧氟沙星制剂杨森制药Janssen80 捷诺达Janumet 西格列汀/二甲双胍复方缓释片默克81 Methylphenidate ER 盐酸哌甲酯缓释片 Watson Pharm公司82 Synagis 帕丽珠单抗美国医学免疫学公司盐酸文法拉辛缓释胶囊以色列锑瓦制药83 怡诺思Venlafaxine HCl ER84 丽眼达Restasis 环孢素眼用乳剂美国艾尔健公司85 斯沃zyvox 利奈唑胺片辉瑞86 倍泰龙Betaseron 干扰素—β-1b 第一三共株式会社87 易维特Evista 雷洛昔芬礼来88 爱必妥Erbitux 西妥昔单抗英克隆公司89 奥坦Benicar 奥美沙坦酯第一三共株式会社90 万珂Velcade 硼替佐米Millenium91 择泰Zometa 唑来膦酸诺华92 优甲乐synthroid 左甲状腺素雅培93 卫喜康Vesicare 琥珀酸索利那新片阿斯特拉斯制药94 希罗达Xeloda 卡培他滨片瑞士罗氏95 得妥Detrol 托特罗定辉瑞96 Opana ER 羟吗啡酮缓释剂日本株式会社远藤公司97 恩瑞舒Orencia 阿巴西普百时美施宝贵98 Prezista 达芦那韦杨森制药Janssen99 万托灵Ventolin HFA 硫酸沙丁胺醇葛兰素史克100 Benicar HCT 奥美沙坦酯氢氯噻嗪片第一三共株式会社101 Cubicin 达托霉素注射液卡比司特制药Cubist 102 Boniva 伊班磷酸钠片瑞士罗氏103 善龙Sandostatin LAR 注射用醋酸奥曲肽微球诺华104 安妥良Actonel 利塞膦酸钠华纳奇考特制药公司(Warner-Chilcott) 105 Sensipar 西那卡塞美国安进106 Amphetamine Salts ER 安非他明缓释剂以色列锑瓦制药107 亚沙卡ASACOL 美沙拉嗪华纳奇考特制药公司（Warner-Chilcott）108 Loestrin 24 FE 复合口服避孕药华纳奇考特制药公司（Warner-Chilcott）109 特凯罗Tarceva 厄洛替尼基因泰克Genentech 110 泰必全Pradaxa 达比加群酯德国勃林格殷格翰BoehringerIngelheim111 雷诺捷Renvela 碳酸司维拉姆片美国健赞Genzyme 112 Gamunex-C 免疫球蛋白注射液西班牙Grifols美国子公司（Grifols USA）113 Pristiq 琥珀酸去甲文拉法辛辉瑞114 右兰索拉唑Dexilant 右兰索拉唑缓释胶囊武田制药Takeda115 Trilipix 非诺贝酸控释胶囊雅培116 Focalin XR 盐酸右哌甲酯缓释胶囊诺华117 安福达Avodart 度他雄胺葛兰素史克118 Xolair 奥马珠单抗基因泰克119 Strattera 阿托西汀礼来120 百泌达Byetta 艾塞那肽注射液艾米林制药公司Amylin121 Humalog Kwikpen 胰岛素注射笔礼来聚乙二醇干扰素α-2a 罗氏122 Pegasys ConveniencePack123 Gammagard Liquid 10%[免疫球蛋白注射液(人用) 百特公司Baxter124 普乐可复Prograf 他克莫司日本安斯泰来制药公司（Astellas Pharma）125 Treanda 注射用盐酸苯达莫司汀以色列锑瓦制药126 维思通risperdal 利培酮长效注射剂杨森制药Janssen 127 Colcrys 秋水仙碱AR Scientific公司128 Norvir 利托那韦雅培129倍美力Premarin 共轭雌激素辉瑞130 NuvaRing 雌二醇+依托孕烯Organon（荷兰Akzo公司的一家子公司）131 Xopenex 左旋沙丁胺醇酒石酸盐sunovion公司132苏为坦Travatan Z 曲伏前列素滴眼液诺华133 Epzicom 阿巴卡韦拉米夫定片ViiV Healthcare134阿喜乐Aloxi 帕洛诺司琼日本卫材药业Eisai 135 Amphetamine Salts ER Global制药136 Fentanyl 芬太尼美国迈兰制药Mylan 137 ACTO plus met 盐酸匹格列酮/盐酸二甲双胍武田制药138脑康平Aggrenox 潘生丁乙酰水杨酸胶囊德国勃林格殷格翰139韦瑞得Viread 替诺福韦酯吉利德科学公司（Gilead Sciences）140 Metoprolol Succinate 琥珀酸美托洛尔缓释片Par141复泰奥Forteo 特立帕肽礼来142安博维Avapro 厄贝沙坦百时美施宝贵143曼月乐mirena 左炔诺孕酮宫内节育系统拜耳医疗保健公司144诺和力Victoza 3-Pak 利拉鲁肽诺和诺德145 Zosyn 哌拉西林钠/三唑巴坦钠注射剂辉瑞146艾斯能Exelo 卡巴拉汀诺华147 Privigen 10%静脉用人体免疫球蛋白加拿大杰特贝林公司CSL Behring148瑞复美Revlimid 来度那胺赛尔基因公司Celgene149 Lexiscan 瑞加德松注射剂安斯泰莱公司Astellas Pharma US 150喜达诺Stelara 优特克单抗山陶克公司(Centocor)151 Adacel 百日咳疫苗赛诺菲安万特152 Ortho Tri-Cyclen Lo 诺孕酯/炔雌醇杨森制药Janssen 153 Welchol 考来维仑第一三共株式会社154 Angiomax 比伐卢定剑桥医药公司The Medicines Co 155加德西Gardasil 宫颈癌疫苗默克156卢美根Lumigan 比马前列素美国眼力健制药157百慕时Pulmozyme 阿发链道酶基因泰克158思维通Invega 帕潘立酮杨森制药Janssen 159密固达Reclast 唑来膦酸诺华160 Temodar 替莫唑胺先灵葆雅161欧克双Xifaxan 利福昔明美国Salix医药公司162 Atorvastatin Calcium 阿托伐他汀钙Watson163 NovoSeven RT 重组人凝血因子诺和诺德164 Bystolic 奈必洛尔美国森林实验室Forest165善思达Invega Sustenna 棕榈酸帕潘立酮缓释注射剂杨森制药Janssen 166 Lialda 美沙拉嗪Shire制药167 Gilenya 芬戈莫德诺华168纽莫法Pneumovax 23 肺炎球菌疫苗默克169怡诺思Effexor XR 文法拉辛缓释胶囊辉瑞170 Kaletra 洛匹那韦/利托那韦雅培171 Zostavax 带状孢疹疫苗默克172 Metoprolol Succinate 琥珀酸美托洛尔Watson173泰索帝Taxotere 多西他赛注射液赛诺菲安万特174 Tysabri 那他珠单抗爱尔兰Elan公司175安理申donepezil 盐酸多奈哌齐美国Greenstone公司176畅沛Chantix 伐尼克兰辉瑞177 Xgeva 狄迪诺塞麦美国安进178 Nutropin AQ （以核糖体DNA为复制起点）注基因泰克射用促生长素179 Fluticasone Propionate 氟替卡松丙酸酯Roxane公司（勃林格Boehringer旗下）180拜复乐AVELOX 莫西沙星先灵葆雅181 Yervoy 易普利姆玛百时美施宝贵182倍博特Exforge 缬沙坦/氨氯地平复方诺华183安立泽Onglyza 沙格列汀百时美施宝贵184凯素Abraxane 紫杉醇蛋白质结合颗粒注射悬液美国赛尔基因185 hydrocodone 氢可酮Watson186欣维可Synvisc-One 透明质酸钠美国健赞Genzyme 187 Zyprexa Zydis 奥氮平礼来188 Bupropion HCL XL 盐酸安非他酮缓释片迈兰制药Mylan 189 QVAR 二丙酸倍氯米松HFA 锑瓦公司190 NovoLog Flexpen Mix 胰岛素注射笔诺和诺德191 Maxalt MLT 利扎曲普坦默克192 Zemplar 帕立骨化醇雅培193 docetaxel 多西他赛美国Hospira公司194稳可信Vancocin 万古霉素Viropharma195利必通lamictal 拉莫三嗪葛兰素史克196 Menactra 脑膜炎疫苗赛诺菲197维达扎Vidaza 阿扎胞苷美国赛尔基因198万赛维Valcyte 缬更昔洛韦罗氏199欧乃派克omnipaque 碘海醇注射液GE医疗集团200 Ranexa 雷诺嗪吉利得Gilead Sciences。
