PCI-CURE – 研究设计
30天
12 月
波立维 75 mg od
+ 标准治疗†
PCI
(n=1313)
开放治疗* 2–4 weeks
30天
12 月
PCI=经皮冠状动脉介入术
安慰剂 1 片 od + 标准治疗†
(n=1345)
* Open-label therapy could include ADP-receptor antagonist in combination with ASA † Standard therapy always included ASA, and could also include heparin, LMWH, GP IIb/IIIa
随访月数
The CURE Investigators. N Eng J Med August 2001 Data on file
CURE --- 主要疗效结果
主要终点 (3)
波立维 +
单纯
RR
CI
标准治疗‡
标准治疗‡
(n=6259)（%） (n=6303)（%）
主要终点 †
9.3
11.4
0.80 0.72–0.90*
inhibitors post-randomization, beta-blockers, ACE inhibitors, lipid-lowering agents, and/or other therapies or interventions (e.g. PTCA, CABG) at physician’s discretion
400 随访天数
The CURE Investigators. Lancet August 2001
