destruction of air space involve the acinus more
or less uniformly.
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Panacinar (panlobular) emphysema
Gross section of lung. Dilated, saccular airspaces. In cases of disease due to a -antitrypsin deficiency,
Magnified section. Distended, intercommunicating, sac-like spaces in central area of acini
In centrilobular emphysema, respiratory bronchioles
are selectively and dominantly involved.
Sputum examination: bacterial culture guide antibiotic treatment
Diagnosis
Chronic cough and sputum production for 3 consecutive months in at least 2 successive years(≥3m/yⅹ2y), excluding other chronic lung diseases (TB, Bronchiectasis )
1
lower part of lung tends to be more affected
Magnified
section.
Diffuse
involvement
of all