世界中医药2023年4月第16卷第7期•1109•玉屏风颗粒联合天灸疗法治疗肺脾气虚型小儿过敏性鼻炎的临床疗效罗齐平刘秋燕胡伟妮肖慧瑜(广州中医药大学附属中山中医院耳鼻喉科,中山摘要目的:观察玉屏风颗粒联合天灸疗法治疗肺脾气虚型小儿过敏性鼻炎的临床疗效及对血清ILC0、ILC和Ig水平的影响。
方法:选取2018年8月至2020年5月广州中医药大学附属中山中医院耳鼻喉科收治的肺脾气虚型过敏性鼻炎患儿40例作为研究对象,随机分为观察组和对照组,每组44例。
对照组给予口服玉屏风颗粒,观察组在对照组基础上联合天灸疗法,在治疗4周后分别比较5组治疗前后鼻部不适症状、中医证候缓解情况、2组间疗效差异以及血清ILC4、ILC 和Ig水平变化。
结果:治疗后观察组和对照组的鼻部症状以及肺脾气虚证候均有明显改善(P<0.05),且观察组总有效率显著优于对照组(P<0.05);治疗后2组ILC0、ILC和Ig水平均降低,观察组明显低于对照组(P<0.05)。
结论:玉屏风颗粒联合天灸疗法治疗肺脾气虚型小儿过敏性鼻炎疗效确切,且优于单独应用玉屏风颗粒者。
关键词玉屏风散;天灸;肺脾气虚型;小儿过敏性鼻炎;中医证候;炎症因子;临床研究;中医儿科CU i S cc I Effect of Yupingfeng Grrnuie Combined with MoxiCustion Therrpy on ChilUree with Allerric RhinitieLUO Qiping,LIN Qiuyan,HU Weini,XIAO Huiyy(Depadmenn p Otolaryngolopne,ZhougsPao Hospn op'70,0,0X10)Chinese Medicine,Guangzhou Universita p Chinese MePiciop,Zhongspan521400,China)Abstrrct Objective:To observe the clinical e/eci of Yupingfeng granules comUined with medicinal vesicu/tion on allergic0X1-Us in children with deficiench of/ny-sp/en qi,and the e/eci on serum IL-10,ILC and IgE/ve/.Methodt:A total of80chilJ paUents with allergic rhinitis caused Uy deficiench of lung-spleen ql abmitwd in the Depart/eni of O//m/Vo/yy,Zhongshan Hospital of TrabiSonai Chinese Medicinv(TCM),Guangziou University of TCM from Aupust2018to FePmam2020were chosen and randomly divided into an observaUon group and a control group,with40cases in each group■The control group was given Yupmv-feng Granule s,and the observaUon group was treated with medicinal vesicu/tion on the basis of the control group■Afteo treatment of 4weeds,the symptoms of nasal discomfort,t he remission of TCM sy/dmme,the dimemnce of clinical e/eci Uetween the5groups as well as the levels of lL-14,ILC and IgE were compared■R csc U c:Afteo treat/ent,the nasal symptoms and deficiench of lung-spleen ql in the5groups were sianificant/000X60(^<0.05)the e/eci of the observaUon group was sianificant/UetWo than con-troi group(P<0.05)■1L-10,ILC and IgE in the5groups were significant/reduced afteo treatment,and the observaUon group was significant//weo than the control group(P<0.05).Conclusion:The e/icach of Yupingfeng Granules comUined with medicinai vesich/tion on allergic rhinitis in child patients with deficiench of lung-spleen ql is better than that of Yupingfeng Granules alone■Keewords Yupingfeng Granules;Medicinal vesich/tion;Deficiench of lung-spleen qi;Allergic rOiniSs in children;TraUitionai Chinese medicine syndrome;AflammaWm facWo;C/nicai research;Pediatrics of TrabiSonai Chinese medicine中图分类号:R246.33;R563.9;S859.79+3文献标识码:A doi:10.3969/B imn.1673-7202.2023.07.016小儿过敏性鼻炎是由基因和环境因素互相作用而诱发的多因素疾患,主要症见鼻痒、鼻塞、阵发性喷嚏、流水样鼻涕等[3]°本病鼻部不适症状反复发作,导致患者生命质量严重降低,日久会并发哮喘、鼻窦炎等,严重影响患者生命质量,同时引发一系列心理疾患。