North America from 1987 to 2006. Anesth Ana恶lg 性20高10热; 1专10业:49知8.识讲座
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体征
Clinical sign Hypercarbia Sinus tachycardia Rapidly increasing temperature Elevated temperature Generalized muscular rigidity Tachypnea Masseter spasm Sweating Cola-colored urine Cyanosis Ventricular tachycardia Excessive bleeding Ventricular fibrillation
Percentage with sign 92.2 72.9 64.7 52.2 40.8 27.1 26.7 17.6 13.7 9.4 3.5 2.7 2.4
Larach MG, Gronert GA, Allen GC, et al. Clini恶ca性l p高res热en专ta业tio知n,识tre讲at座ment, and complications o7f malignant hyperthermia in North America from 1987 to 2006. Anesth Analg 2010; 110:498.
•5-羟色胺综合征–多种药物可增加5-羟色胺的活性,过量摄入这些药物或不慎发生了这些药物相互作用就会导致5-羟色胺综合征。5-羟色胺综合征与MH有 许多共同的体征(心动过速、血压波动、高热和肌肉强直),并且均会存在CK水平升高和代谢性酸中毒,但5-羟色胺综合征可出现MH没有的体征(震颤、阵挛、 反射亢进、静坐不能和瞳孔放大)。