在两块玻璃板尚未键合时板间空气间隙承担了大部分电压降玻璃板可视为平行板电容器板间吸引力与电场强度的平方成正比因此键合从两块玻璃中那些最接近的点开始下板中可移动的正电荷主要是na与上板中的负电荷中和生成一层氧化物正是这层过渡层使两块玻璃板封接该点完成键合后周围的空气间隙相应变薄电场力增大从而键合扩散开来直至整块密合
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• The concept of "miniaturized total chemical analysis system" or TAS was proposed by Manz et al.
• the main reason for miniaturization was therefore to enhance the analytical performance of the device rather than to reduce its size.
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• Micro Total Analysis System
(MicroTAS, TAS)
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Why miniaturization？
Research into miniaturization is primarily driven by the need to reduce costs by reducing the consumption of expensive reagents and by increasing throughput and automation.
• A novel concept of high pressure liquid chromatog.
• a silicon chip with an open-tubular column and a conductometric detector.
