US-FNAB 技术及超声弹性成像技术在TI-RADS 4类甲状腺结节中的诊断价值史文洁1，谢伟2，张爱华11.句容市人民医院超声科，江苏句容 212400；2.句容市人民医院普外科，江苏句容 212400摘要 目的 探究超声引导细针穿刺活检技术（ultrasound-guided fine needle aspiration biopsy ， US-FNAB ）及超声弹性成像技术在TI-RADS 4类甲状腺结节中的诊断价值。
方法 采用随机抽样法选取句容市人民医院在2020年5月—2023年5月收治的86例甲状腺结节患者作为研究对象，均分别采取US-FNAB 及超声弹性成像技术（ultrasonic elastography ， UE ）进行检查，以病理学检查作为金标准，评估US-FNAB 技术及UE 技术对TI-RADS 4类甲状腺结节的诊断效能。
结果 经病理学检查结果可知，86例患者中，共存在102个结节，其中恶性结节74个，良性结节28个。
UE 检查结果显示，恶性结节72个，良性结节30个，相比病理学检查，恶性结节检出率为86.49%，US-FNAB 检查结果显示，恶性结节72个，良性结节30个，相比病理学检查，恶性结节检出率为94.59%。
US-FNAB 特异度92.86%、准确率94.12%、灵敏度94.59%，均高于UE 的71.43%、82.35%、86.49%，差异有统计学意义（P<0.05）。
结论 在疑似TI-RADS 4类甲状腺结节患者的诊断中，采用US-FNAB 技术的诊断效能明显高于超声弹性成像技术。
关键词 US-FNAB 技术；超声弹性成像技术；TI-RADS 4类甲状腺结节；特异度；灵敏度；准确度中图分类号 R 445445..1 文献标志码 Adoi10.11966/j.issn.2095-994X.2023.09.07.26The Diagnostic Value of US-FNAB Technique and Ultrasonic Elastography in TI-RADS 4 Thyroid NodulesSHI Wenjie 1, XIE Wei 2, ZHANG Aihua 11.Department of Ultrasound, Jurong People's Hospital, Jurong, Jiangsu Province, 212400 China;2.Department of General Surgery, Jurong People's Hospital, Jurong, Jiangsu Province, 212400 ChinaAbstract Objective Exploring the diagnostic value of ultrasound guided fine needle aspiration biopsy (US-FNAB) and ultrasound elastogra‐phy in TI-RADS type 4 thyroid nodules. Methods 86 patients with thyroid nodules admitted to Jurong People's Hospital from May 2020 to May 2023 were selected as the study subjects using random sampling method. Both US-FNAB and ultrasound elastography (UE) were used for examination, and pathological examination was used as the gold standard to evaluate the diagnostic efficacy of US-FNAB and UE tech‐niques for TI-RADS type 4 thyroid nodules. Results According to pathological examination results, a total of 102 nodules were present in 86 patients, including 74 malignant nodules and 28 benign nodules. The UE examination results showed 72 malignant nodules and 30 benign nodules, with a detection rate of 86.49% compared to pathological examination. The US-FNAB examination results showed 72 malignant nod‐ules and 30 benign nodules, with a detection rate of 94.59% compared to pathological examination. The specificity, accuracy, and sensitivity of the US-FNAB were 92.86%, 94.12%, and 94.59%, respectively, which were higher than those of the UE 71.43%, 82.35%, 86.49%, the dif‐ference was statistically significant (P <0.05). Conclusion In the diagnosis of type 4 thyroid nodules suspected to be TI-RADS, US-FNAB technique is significantly more effective than ultrasound elastography.Key words US-FNAB technology; Ultrasonic elastic imaging technology; TI-RADS type 4 thyroid nodules; Specificity; Sensitivity; Accu‐racy* 器材应用与技术研究 *收稿日期：2023-06-02；修回日期：2023-06-22作者简介：史文洁（1990-），女，本科，主治医师，研究方向为超声医学。
