•妇产科研究窑系统医学2017年8月第2卷第16期DOI:10.19368/ki.2096-1782.2017.16.084医用生物胶体分散剂联合雌三醇软膏阴道上药在 子宫切除术后对阴道残端愈合的影响周勤英，李巧云，毋蓓蓓郑州大学第五附属医院妇产科，河南郑州450052[摘要]目的探讨生物胶联合雌三醇软膏在子宫全切术后阴道残端愈合的影响。
方法将该院2015年9月一2017 年1月年龄在46~65岁之间150例，行子宫全切术患者术前术后阴道应用医用生物胶体分散剂联合雌三醇软膏作为观察组，术前术后应用0.5%碘伏阴道擦洗作为对照组，术后5d及术后1月对两组患者阴道分泌物清洁度异常、流血、阴道残端息肉（肉芽)形成情况等指标进行评判。
结果观察组术后5d阴道分泌物清洁度异常、p H 值阳性率、细菌性阴道病发生率、阴道残端流血及肉芽形成发生率、阴道用药时疼痛不适感发生率分别为6.7%、9.3%、6.7%、8.0%、8.0%s与对照组相比差异无统计学意义(P>0.05〉；观察组术后1个月阴道分泌物清洁度异常、p H值阳性率、细菌性阴道病发生率、阴道残端流血及肉芽形成发生率、阴道用药时疼痛不适感发生率分别为8.0%、6.7%、5.3%、6.7%、6.7%，明显优于对照组(P<0.05)。
结论对于行子宫全切卵巢功能减退患者术前术后应用医用生物胶体分散剂喷洒外阴阴道局部涂抹雌三软膏取得良好的效果。
[关键词]医用生物股体分散剂；雌三醇软膏；全子宫切除术；阴道残端[中图分类号]R713.42[文献标识码]A[文章编号]2096-1782(2017)08(b)-0084-03Effect of Medical Biocolloid Dispersing Agent and Vaginal Dressing of Estriol Cream on the Vaginal Residual End Healing after HysterectomyZHOU Qin-ying, LI Qiao-yun, WU Bei-beiDepartment of Gynecology and Obstetrics, Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou, H e n a nProvince, 450052 China[Abstract] Objective To study the effect of medical biocolloid dispersing agent and vaginal dressing of estriol cream on the vaginal residual end healing after hysterectomy. Methods 150 cases of patients aged between 46 and 65 years old from September 2015 to January 2017 were selected, the observation group were treated with medical biocolloid dispersing agent and vaginal dressing of estriol cream before and after operation, while the control group applied the0.5% iodophor vaginal cleaning before and after operation, and the vaginal fluid cleanliness abnormality, bleeding, formation of vagina remnant end polyp (granulation) were determined after 5 d and 1-month operation. Results The vaginal fluid cleanliness abnormality rate, p H value positive ra te, incidence rate of bacterial vaginal disease, incidence rate of vaginal stump bleeding and incidence rate of granulation and incidence rate of pains discomfort of vaginal at vaginal medication were respectively 6.7%，9.3%，6.7%，8.0%，8.0%，and the differences between the two groups were statisti ca ll y significant (P>0.05) and the vaginal fluid cleanliness abnormality, p H value positive ra te, incidence rate of bacterial vaginal disease, incidence rate of vaginal stump bleeding and granulation formation and incidence rate of pain discomfo r t at vaginal medication were respectively 8.0%，6.7%，5.3%，6.7%，6.7%，which were obviously better than those in the control group (P<0.05). Conclusion The application effect of medical biocolloid dispersing agent and vaginal dressingof estriol cream in patients with total hysterectomy hyop-ovarianism before and after operation i s good.[Key words] Medical biocolloid dispersing agent; Estriol cream; Total hysterectomy; Vaginal stump全子宫切除术目前是妇科治疗常见的手术，随着 手术技术提高及先进的医疗器械的应用，阴道残端愈 合不良发生率较前明显降低，由于中老年女性雌激素 水平降低，局部抵抗力下降，在临床中仍不可避免出 现此类并发症'影响患者的生活质量，增加患者的经[作者简介]周勤英（1978-)，女，河南商水人，硕士，主治医 师，研究方向:妇科肿瘤及微创。
