millipore膜维护手册

Millipore密理博纯水系统常见问题集2011-04-08蓝宝书系列之二纯水系统常见问题集FAQ市场部2005目录纯水系统使用常见问题 (1)1．1 纯水制备系统 (1)1. Millipore纯水系统是否可以追溯至NIST的检测？ (1)2. Progard 柱中有多少抗结垢剂？在什么水平下，需要额外添加软化剂。

13. Millipore 纯水系统能否显示真正的电阻率？ (1)4．反渗透膜的孔径100道尔顿，离子都小于100道尔顿。

为什么反渗透膜能够清除离子？ (2)5. 为什么在反渗透（RO）纯化柱使用聚酰胺薄膜（TFC PA）而不是醋酸纤维素脂（CA）膜？ (2)6. EDI 是如何去除有机物的？ (3)7．为什么在EDI模块的阴极有碳粒？ (3)8. Elix 对进水的TOC 含量有没有特殊要求？要求是什么？ (3)9. Elix 水纯化系统是如何去除水中的气体（CO2）? (3)10. 在保证产水细菌含量<1cfu/ml的条件下，Elix所能承受的供水细菌最大含量是多少？ (3)1．2 超纯水制备系统 (4)1. 为什么超纯水的电阻率为18.2 MΩ.cm，而不是18.3 MΩ.cm? (4)2. 为什么我们不能离线检测超纯水的电阻率? (4)3. 为什么Milli-Q的产水流量为1.5L/min? (5)4. 为什么Milli-Q系统有一个进水电磁阀？ (5)5. 为什么Milli-Q系统有一个网式过滤器? (5)6. 如何计算纯化柱的纯化能力和使用寿命？ (5)7. 当Milli-Q 超纯水系统处于Standby（待机）/ Preoperate (预操作)模式时，如何确定系统内部的水不会有细菌滋生？ (6)8. 为什么终端过滤器的孔径只有0.22微米，而不是0.45 微米？ (6)9. 饮用水机安装的UV灯和 Milli-Q Gradient (超低有机物型)所使用的UV灯有什么不同？ (7)10. Milli-Q Gradient(超低有机物型) 如何将TOC含量降到5ppb以下？.711. 我用Milli-Q Gradient系统不能获得TOC含量小于5ppb的水，我的进水是去离子水。

更换过滤柱1) 将机器调节为STANDBY”状态，卸下终端过滤器，打开取水开关，将系统卸压，待确认机器无水流出后，关闭取水开关。

2) 向左轻扳机器正面蓝色门的锁片（上下各一片），打开蓝门，将“QUANTUM”柱取出，再将机器右侧白色“QGARD”柱上端盖子打开，取下金属锁片，即可取出“QGARD”柱。

3) 将新的“QGARD”柱装到机器上，注意机器上的金属杆要对准柱子上的孔，向左推紧后，将金属锁片锁在金属杆的卡槽内，扣上顶端盖子；再将新的“QUANTUM”柱装入蓝门内，稍用力向里推紧，关闭蓝门，需听到两个锁片“嗒”的声音后，才能确认柱子已装到位。

4) 将附件中的管子接头拧入取水柄中，接上软管引到水槽里；打开取水开关，系统会自动进入5分钟的排空气程序中，5分钟结束后，系统会自动进入“OPERATE”状态。

5) 卸下管子接头及软管，装上终端过滤器；注意过滤器上的空气帽不要拧紧，打开取水开关，待水从空气帽中流出后，再拧紧空气帽。

6) 柱子更换完毕，将系统在“OPERATE”状态下过12小时以上，便可正常使用。

如何判断柱子是否寿命已到1) 当系统已使用一段时间后，首先检查，当取水开关打到循环位置时，查看显示屏的电阻率由初始值升到18.2MΩ·cm时，需要多少时间，正常情况不会超过1分钟，或在产水过程中，出现电阻率下降(不稳定)的情况时，均证明柱子的寿命已快到期了。

2) 如果出现产水流量明显下降(正常每分钟为1-1.5L左右)，在确认系统中确实无空气的前提下，多数是因为终端过滤器已堵塞而所至。

3) 为确保系统能正常运转，以及最经济的使用过滤材料(过滤柱等)，建议在更换耗材时，最好统一一起更换。

MILLI-Q 超纯水机使用技巧1) 工作中有时因为疏忽大意，会忘将进水水桶中加水，会使机器进空气，此时机器显示屏上会显示"AIR PURGE"，这时，只需打开取水开关（开到产水位置），显示屏会显示"AIR PURGE 5MN"，待5分钟后，显示屏会显示"CLOSE THE VALVE"，此时只需关闭取水开关，机器就可以正常工作了。

A10總有機碳檢測器操作手冊MILLIPORE1最初啟動注意：在「Clean」狀態下持續按「Mode」三秒以上會重置UV燈計時。

自動檢測模式用及運送當中A10有可能被污染，所以使用前長時間清洗是非常重要的，在「自我清洗」中A10中的UV會開啟3分鐘以氧化所有殘留的有機物，然後會熄燈一分鐘來冷卻，如此反覆維持到「Mode」按鍵被觸動或電源，連接被改變在「自我清洗」過程中，內部的電磁閥會一直維持在「開」的狀態，使樣本持續流出。

如何開始「自我清洗」狀態：1.拔掉A10側邊電源插頭。

2.在先按住「Mode」按鍵的狀態下插回電源插頭，然後放掉按鍵，顯示幕會出現「Clean」字眼。

3.使A10在這狀態運作一小時，然後按「Mode」，使其進入檢測狀態。

在清洗完後，檢測幾項以確定數據是否穩定，並注意進出口是否有小氣泡存在，這將會嚴重影響讀值，A10 TOC檢測器共有三種操作模式，「自動檢測」、「手動檢測」及「待機」，除非有所改變，狀態會一直維持，A10的活動狀態則是用記號「*」來指示，如果有了一次以上的檢測數據，則「Analysis」顯示會被數值取代。

Millipore建議長期持續使用A10才會有穩定極準確的數值出現，否則每次使用時，要捨棄前三次數據。

接上電源或按一次「Mode」按鍵會隨時進入此狀態，然後會持續顯示最後一次檢測出數據。

2Note:閃爍的數據通常表示之前的或有問題的Fill Time Note:自動及手動檢測接由此設定在「Fill」狀態下，趕測室會持續沖洗使用者設定之時間，而第一次檢測時，A10會自動的家30秒鐘。

「自動檢測」會持續至外部指令改變，一組閃爍的數據表示是顯示就記錄並可能是不可靠的。

如有任何錯誤被檢測出來，儀器會自動進入兩次「recovery」之常識，如果成功，則進入正常檢測狀態，但如果失敗，A10會進入「待機」狀態，並顯示「Error」，這時請對照「錯洗表」中之說明或重新按「Mode」鍵啟動。

Millipore BioProcesss Division维护手册Pellicon & Pellicon 2超滤膜堆MILLIPORE目录：手册使用方法……………………………………………………P 3 Pellicon & pellicon 2 膜堆…………………………………P 4冲洗步骤…………………………………………………………P 5清洗步骤…………………………………………………………P 6 消毒步骤…………………………………………………………P10 除热原步骤………………………………………………………P11水通量的测量……………………………………………………P12膜堆的完整性检测………………………………………………P14储存步骤…………………………………………………………P17化学兼容性………………………………………………………P19本手册对如何维护Millipore公司生产的切向流超滤膜、膜堆和超滤系统提供了一些建议。

这些建议是根据我们现有的经验和实践编写的，没有将所有可能用到的清洗、消毒和除热原的方法全部列出。

如果本手册中提供的方法不适合于您的应用，请与Millipore公司技术服务部门联络，以获取进一步的信息。

手册使用方法本手册详细介绍了以下的维护程序：•冲洗•清洗•消毒•除热原•水通量NWP的检测•完整性测试方法•保存本手册介绍了在每一步操作时超滤系统的连接方式，以及建议使用的切向流速和膜透压。

在清洗条件建议表中,列明了各种清洗剂的浓度、pH值、时间、温度和与膜的化学兼容性。

清洗剂选择表可以帮助用户根据不同的应用和污染情况，选择相应的清洗剂。

但是很难预测出所有应用所需的清洗剂，所以在清洗剂选择表中也同时列出了可供选择的其他清洗剂。

有一些应用可能需要两步清洗。

在这种情况下，必须用水将第一种清洗剂从超滤系统中完全冲洗干净之后，才可以使用第二种清洗剂，以免不同的清洗剂之间发生对膜堆有害的化学反应。

Pellicon○R2盒式膜包使用指南Pellicon,Durapore,Ultracel和Biomax是密理博公司的注册商标，M的标识是德国达姆施塔特的默克公司的商标，Tween是美国ICI公司的注册商标，Tergazyme是Alconox公司的注册商标，Triton是美国联合碳化物公司的注册商标。

©2003年，2011年Millipore公司。

保留所有权利。

P35430 D版，09/2011目录前言 (3)膜类型 (3)膜包之间的垫片 (3)泵流量 (3)水的质量要求： (4)名义截留分子量（NMWL） (5)安装 (6)冲洗操作 (7)进液流道（Feed Channel）冲洗 (7)透过流道冲洗 (7)清洗操作 (8)进液流道清洗 (8)透过流道的清洗 (8)冲洗 (9)消毒操作 (11)除热原操作 (12)完整性测试操作 (13)标准水通量(NWP)测量 (15)保存步骤 (17)进液流道冲洗 (17)透过流道冲洗 (17)故障排除 (19)一般有限保修条款 (20)技术支持 (20)前言本使用手册提供Pellicon○R2膜包安装和维护程序。

并不提供验证程序或支持验证目的的数据。

这方面的信息请参考验证指南。

膜类型在一个膜夹具上一次只能安装一种类型的膜包。

不能将不同孔径或名义截留分子量的膜包混装在一起。

膜的数量取决于特定应用所需的过滤面积。

避免用手接触滤膜表面。

膜包之间的垫片所有的Pellicon○R2盒式膜包（0.5 m2）和Maxi 膜包（2.5 m2）的包装盒中都装有两个硅胶垫片，用于膜包安装过程中安装在膜包之间。

泵流量当操作Pellicon○R2 膜包，应确保选择能够提供足够流量的泵，推荐的切向流速是：A和C 流道装置：4-6L/min/m2V流道装置：5-35L/min/m2优化的切向流速应参照实际的超滤的溶液和产品。

水的质量要求：名义截留分子量（NMWL）安装Pellicon ○R2膜包应安装于一个Pellicon ○R2夹具中，安装请参考夹具安装手册。

Data SheetLC-Pak®LCPAK00A1IntroductionThe LC-Pak® polisher is areverse-phase C18 granularsilica-based cartridge. It has beenvalidated to produce 500 L of watersuitable for trace and ultra-traceorganic analysis, when fed withMilli-Q® ultrapure water.Ultrapure water treated by anLC-Pak® polisher is suitable foreluent, buffer or blank preparation,sample dilution and standardpreparation, as well as columnrinsing in applications such asUHPLC, LC-MS, LC-MS-MS.Instructions are available as aself-guided wizard, directly on theQ-POD® dispenser display of theMilli-Q® IQ 7000. You can accessthem from the Consumables menuor the Maintenance menu.For more information, refer tothe user manual or quick guide.The life science business of Merck operates asMilliporeSigma in the U.S. and Canada.2Note:The flow tip can be located either on your old LC-Pak ® or, if it is a new a installation, it is provided with the Application-Pak installation kit (EDSKIT001).1. Remove the new LC-Pak ® from the package.2. Remove and discard the caps at the inlet and outlet of the cartridge.3. Install the flow tip at the outlet.Step 21. Syringe adapter2. Clean glass Luer slip tip syringe (50 mL) *3. 50 mL of high grade methanol *Required material for LC-Pak ® conditioning:Step 1Conditioning• The LC-Pak ® polisher is manufactured, packed and shipped dry.• Prior to installation, it is necessary to condition its reverse-phase silica with high grade methanol (99.9+%).W ear eye safety glasses, laboratory gloves and other appropriate safety equipment when working with methanol.* Purchased separately.23• T wist the new LC-Pak ® into place.Flush the cartridge with ultrapure water for at least 10 minutes.• T he LC-Pak ® installation is now complete. You can dispense ultrapure water from the cartridge for your application.• R emove the expired Application POD-Pak if any.Step 4Step 5Step 6Step 7Installation• The LC-Pak ® cartridge has a Luer female inlet connection designed for direct connection to the outlet of Q-POD ® remote dispenser of Milli-Q ®IQ 7000 system.1. Press the dispenser wheel to start rinsing.2. After 10 minutes (at least 20 L) of rinsing, press the dispenser wheel again to complete the installation.Your LC-Pak ® certificate of quality is available onLit. No. DS5434ENEU Ver. 1.02017 - 0634701/2018OperationEvery day, discard the first liter of water produced by the water purification system to minimize environmental contamination from the water outlet.Multiple applicationsIf water dispensed requires bacteria levels below 0.1 CFU/mL and particles < 0.22 μm, you can adapt a Millipak ® filter after the LC-Pak ® cartridge using the connector provided in the installation and conditioning kit (EDSKIT001).Water purified through this cartridge may not be suitable for other applications.For your Milli-Q ® water to match several applications, you may connect up to 4 Q-POD ® remote dispensers to your Milli-Q ® production unit. Install your LC-Pak ® at the outlet of one Q-POD ® dispenser and select amongst our range of POD-Paks the suitable ones for your other applications (visit )MaintenanceValidation tests performed in our laboratories have demonstrated that, once conditioned, the LC-Pak ® cartridge can deliver ultrapure water suitable for UHPLC, LC-MS, LC-MS-MS applications for at least 500 liters when fed by ultrapure water from a Milli-Q ® IQ 7000 water purification system.Feed waterResistivity 18.2 MΩ.cm @ 25°C and TOC < 5 ppb Inlet connectionLuer female Water temperature5 – 30°C Cartridge lifetime 500 litersHousingPolypropylene ConnectorPolyethylene Purification mediaReverse-phase silica beads Sintered filterPolypropylene Reverse-phase silica compression disc PolypropyleneDescriptionCat. No.LC-Pak ® polisherLCPAK00A1Application-Pak Installation Kit EDSKIT001© 2018 Merck KGaA, Darmstadt, Germany and/or its affiliates. All Rights Reserved. Merck, the vibrant M, LC-Pak, Milli-Q, Millipak and Q-POD are trademarks of Merck KGaA, Darmstadt, Germany and/or its affiliates. All other trademarks are the property of their respective owners. Detailed information on trademarks is available via publicly accessible resources.Merck KGaA Frankfurter Strasse 250, 64293 Darmstadt, Germany。

T F F切向流超滤膜包维护手册本手册对如何维护Millipore公司生产的切向流超滤膜、膜堆和超滤系统提供了一些建议。

这些建议是根据我们现有的经验和实践编写的，没有将所有可能用到的清洗、消毒和除热原的方法全部列出。

如果本手册中提供的方法不适合于您的应用，请与Millipore公司技术服务部门联络，以获取进一步的信息。

手册使用方法本手册详细介绍了以下的维护程序：???? 冲洗???? 清洗???? 消毒???? 除热原???? 水通量NWP的检测???? 完整性测试方法???? 保存本手册介绍了在每一步操作时超滤系统的连接方式，以及建议使用的切向流速和膜透压。

在清洗条件建议表中,列明了各种清洗剂的浓度、pH值、时间、温度和与膜的化学兼容性。

清洗剂选择表可以帮助用户根据不同的应用和污染情况，选择相应的清洗剂。

但是很难预测出所有应用所需的清洗剂，所以在清洗剂选择表中也同时列出了可供选择的其他清洗剂。

有一些应用可能需要两步清洗。

在这种情况下，必须用水将第一种清洗剂从超滤系统中完全冲洗干净之后，才可以使用第二种清洗剂，以免不同的清洗剂之间发生对膜堆有害的化学反应。

选择清洗方法：1.从清洗剂选择表中，找出类似的应用或可能的污染物。

2.选择与所使用的膜堆兼容的清洗剂。

3.从清洗条件建议表中，找出对应的清洗剂的操作条件。

选择消毒、除热原和保存剂的方法与此相同。

注：1.一定要确认您选择的清洗剂与膜材质是兼容的。

2.所有新膜堆在安装后第一次使用之前，必须进行冲洗和清洗。

3.清洗好的新膜堆要用纯水测定水通量NW P。

冲洗步骤Pellicon盒式膜堆在使用前后及清洗前都应冲洗，在每次清洗、消毒和除热原之后也要进行冲洗，以便将化学试剂冲洗干净。

1.?? 将透过管路和回流管路处于排放状态，确保在冲洗过程中没有液体流回清洗罐中。

2.? 在清洗罐中加入40－50℃的纯水（经过过滤的去离子水、注射用水或反渗透水）或缓冲液，如果水会导致系统和膜堆内溶质的沉淀，就必须用合适的缓冲液冲洗后才进行清洗。

Millipore BioProcesss Division维护手册Pellicon & Pellicon 2超滤膜堆MILLIPORE目录：手册使用方法……………………………………………………P 3 Pellicon & pellicon 2 膜堆…………………………………P 4冲洗步骤…………………………………………………………P 5清洗步骤…………………………………………………………P 6 消毒步骤…………………………………………………………P10 除热原步骤………………………………………………………P11水通量的测量……………………………………………………P12膜堆的完整性检测………………………………………………P14储存步骤…………………………………………………………P17化学兼容性………………………………………………………P19本手册对如何维护Millipore公司生产的切向流超滤膜、膜堆和超滤系统提供了一些建议。

这些建议是根据我们现有的经验和实践编写的，没有将所有可能用到的清洗、消毒和除热原的方法全部列出。

如果本手册中提供的方法不适合于您的应用，请与Millipore公司技术服务部门联络，以获取进一步的信息。

手册使用方法本手册详细介绍了以下的维护程序：∙冲洗∙清洗∙消毒∙除热原∙水通量NWP的检测∙完整性测试方法∙保存本手册介绍了在每一步操作时超滤系统的连接方式，以及建议使用的切向流速和膜透压。

在清洗条件建议表中,列明了各种清洗剂的浓度、pH值、时间、温度和与膜的化学兼容性。

清洗剂选择表可以帮助用户根据不同的应用和污染情况，选择相应的清洗剂。

但是很难预测出所有应用所需的清洗剂，所以在清洗剂选择表中也同时列出了可供选择的其他清洗剂。

有一些应用可能需要两步清洗。

在这种情况下，必须用水将第一种清洗剂从超滤系统中完全冲洗干净之后，才可以使用第二种清洗剂，以免不同的清洗剂之间发生对膜堆有害的化学反应。

Millipore BioProcesss Division维护手册Pellicon & Pellicon 2超滤膜堆MILLIPORE目录：手册使用方法……………………………………………………P 3 Pellicon & pellicon 2 膜堆…………………………………P 4冲洗步骤…………………………………………………………P 5清洗步骤…………………………………………………………P 6 消毒步骤…………………………………………………………P10 除热原步骤………………………………………………………P11水通量的测量……………………………………………………P12膜堆的完整性检测………………………………………………P14储存步骤…………………………………………………………P17化学兼容性………………………………………………………P19本手册对如何维护Millipore公司生产的切向流超滤膜、膜堆和超滤系统提供了一些建议。

这些建议是根据我们现有的经验和实践编写的，没有将所有可能用到的清洗、消毒和除热原的方法全部列出。

如果本手册中提供的方法不适合于您的应用，请与Millipore公司技术服务部门联络，以获取进一步的信息。

手册使用方法本手册详细介绍了以下的维护程序：•冲洗•清洗•消毒•除热原•水通量NWP的检测•完整性测试方法•保存本手册介绍了在每一步操作时超滤系统的连接方式，以及建议使用的切向流速和膜透压。

在清洗条件建议表中,列明了各种清洗剂的浓度、pH值、时间、温度和与膜的化学兼容性。

清洗剂选择表可以帮助用户根据不同的应用和污染情况，选择相应的清洗剂。

但是很难预测出所有应用所需的清洗剂，所以在清洗剂选择表中也同时列出了可供选择的其他清洗剂。

有一些应用可能需要两步清洗。

在这种情况下，必须用水将第一种清洗剂从超滤系统中完全冲洗干净之后，才可以使用第二种清洗剂，以免不同的清洗剂之间发生对膜堆有害的化学反应。

MINI-RESERVOIRRC800User GuideNoticeThe information in this document is subject to change withoutnotice and should not be construed as a commitment by Millipore Corporation. Millipore Corporation assumes no responsibility for any errors that may appear in this document. This manual isbelieved to be complete and accurate at the time of publication. In no event shall Millipore Corporation be liable for incidental or consequential damages in connection with or arising from the use of this manual.© 2004 Millipore Corporation. All rights reserved.Millipore and Amicon are registered trademarks of Millipore Corporation.Delrin is a registered trademark of E.I. du Pont de Nemours.99137, Rev. J, 09/04Contents Introduction (1)Chemical and Temperature Resistance (1)Sterilization (1)Diagram of Mini-Reservoir RC800 Components (2)Setup (3)Diagram of Inlet/Outlet Fitting Components (3)Operation (4)Shutdown (4)Cleaning and Maintenance (4)System Disassembly (4)System Reassembly (4)Ordering Information (5)Specifications (6)Materials of Construction (6)Technical Assistance (6)Standard Warranty (7)IntroductionThis 800 mL auxiliary reservoir (product no. 6028) increases the volume capacity of Millipore ultrafiltration cells. When pressur-ized from an external gas source, RC800 automatically replen-ishes liquid in the cell’s built-in reservoir during filtration (due to the pressure differential between the two containers). With RC800 attached, volumes exceeding normal cell capacity can be processed unattended. The reservoir may also be used to store dialysate during diafiltration or dialysis.Chemical and Temperature ResistanceDO NOT use reservoir with alcohols, strong acids, oxidizing agents, strong bases or organic solvents (esters, ketones, aro-matic and chlorinated hydrocarbons). DO NOT subject unit to temperatures over 100 °F (38 °C).SterilizationUse standard sterilizing gas mixtures or a 5% formalin solution. The RC800 reservoir is not autoclavable. DO NOT use alcohol. Diagram of Mini-Reservoir RC800 ComponentsLetter DescriptionA Top capB Tubing, 1/4” OD polyethylene, 2 × 4 ft.C Liquid outlet fittingD Gas inlet fittingE Pressure relief valve assemblyF O-ring (relief valve)G Recessed portH O-ring (reservoir sleeve)I Tubing, 1/4” OD polyethylene, 1 × 4 3/4 in.J Reservoir sleeveK Bottom capL Strap assemblyMini-Reservoir RC800 User Guide3 Setup1.Connect an appropriate length of supplied tubing to gas inletfitting on the reservoir top cap (marked “G”) as follows:a.Unscrew hexagonal nut and remove the O-ring.b.Slide nut, grab ring, spacer (countersunk side towardgrab ring), and O-ring onto tubing. Leave no more than½” (13mm) of tubing beyond grab ring.c.Insert exposed tubing into reservoir fitting; hand tightennut.d.Connect free end of tubing to fitting of an external gassource.2.Repeat step 1 to connect tubing to liquid outlet fitting on thereservoir top cap (marked “L”). Connect free end of thistubing to ultrafiltration cell.3.Remove pressure-relief valve assembly from top cap. Addliquid to reservoir sleeve; then replace valve assembly,making sure O-ring is in place. Hand tighten.Diagram of Inlet/Outlet Fitting ComponentsLetter DescriptionA Hexagonal nutB Grab ringC SpacerD O-ring OperationTurn on gas and slowly pressurize reservoir. Check connections for leaks, then increase pressure as desired. Liquid will flow continuously from reservoir into cell until the pressures in the two containers equalize.CAUTION:DO NOT operate reservoir at pressures over 75 psi(5.2 bar).ShutdownTurn off gas supply to reservoir. To vent system, turn upper portion of pressure relief valve.Cleaning and MaintenanceIn normal use, this unit should not be disassembled. To add buffer or introduce cleaning solutions, remove the pressure relief valve assembly and add liquid through the recessed port.If disassembly is required, the procedures below must be strictly followed.System Disassembly1.Vent system pressure and disconnect gas and liquid tubing.2.Remove pressure-relief valve assembly.3.Remove reservoir assembly from trapezoidal strap assembly.4.Pry top and bottom caps from reservoir sleeve, using toolprovided.5.Remove O-rings from top and bottom caps.6.Wash all parts with soap and water.System Reassembly1.Inspect O-rings for cuts or wear; if necessary, replace anydamaged ones with spares.2.Lubricate O-rings with glycerin or water and reposition themon top and bottom caps.3.Push top and bottom caps into reservoir sleeve until properlyseated, then slide reservoir assembly into strap assembly.Mini-Reservoir RC800 User Guide5 Ordering InformationThis section lists the catalogue numbers for the Mini-Reservoir RC800 and its replacement and accessory parts. See the Techni-cal Assistance section for information about contacting Milli-pore.Replacement Parts Catalogue No.Qty Top cap209731 Reservoir sleeve209611 Bottom cap209591O-ring (reservoir sleeve)2239S4 Tubing 1/4" OD polyethylene XXPE 000 1010 ft. Pressure relief valve assembly10021021O-ring (relief valve)2015B2Gas inlet/liquid outlet fitting, elbow,420130100231/4 × 1/4" NPTStrap assembly153241 Cap removal tool211431 Accessory Equipment Catalogue No.Qty CDS10 Concentration/Dialysis Selector60031 For instant switching from concentrationto rapid dialysis (Diafiltration).MF2 Push-Button Manifold60151 For operation of multiple cells orreservoirs; individually valved.TA1 Tubing Adapter Kit60221 Adapts plastic tubing to 1/8" or 1/4" maleor female gas fittings. SpecificationsCapacity: 800 mLHoldup volume: 4 mLMaximum operating pressure: 75 psi (5.2 bar)Dimensions of reservoir assembly:4 3/4 in. diameter ×5 1/4 in. high (12 cm × 13.3 cm)Weight (including strap): 3.7 lbs (1.7 kg)Materials of ConstructionReservoir sleeve: acrylicTop and bottom caps: Delrin® resinTubing fittings: nylonTubing: polyethyleneO-rings (red): silicone rubberO-rings (black): Buna-N nitrile rubberCompliance with the Pressure Equipment Directive, 97/23/ECMillipore Corporation certifies that this product complies with the European Pressure Equipment Directive, 97/23/EC of 29 May 1997.This product is classified under Article 3 § 3 of the Pressure Equipment Directive. It has been designed and manufactured in accordance with sound engineering practice to ensure safe use. The product is accompanied by user instructions and bears markings to permit identification of Millipore Corporation as the manufacturer or authorized representative of this product within the European Community.In compliance with Article 3 § 3 of the Pressure Equipment Directive, this product does not bear the CE mark.Mini-Reservoir RC800 User Guide7 Technical AsssistanceFor more information, contact the Millipore office nearest you. In the U.S., call 1-800-MILLIPORE (1-800-645-5476). Outside the U.S., see your Millipore catalogue for the phone number of the office nearest you or go to our web site at/offices for up-to-date worldwide contact information. You can also visit the tech service page on our web site at /techservice.Standard WarrantyMillipore Corporation ("Millipore") warrants its products will meet their applicable published specifications when used in accordance with their applicable instructions for a period of one year from shipment of the products. MILLIPORE MAKES NO OTHER WARRANTY, EXPRESSED OR IMPLIED. THERE IS NO WARRANTY OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE. The warranty provided herein andthe data, specifications and descriptions of Millipore products appearing in Millipore's published catalogues and product literature may not be altered except by express written agree-ment signed by an officer of Millipore. Representations, oral or written, which are inconsistent with this warranty or such publications are not authorized and if given, should not be relied upon.In the event of a breach of the foregoing warranty, Millipore's sole obligation shall be to repair or replace, at its option, the applicable product or part thereof, provided the customer notifies Millipore promptly of any such breach. If after exercis-ing reasonable efforts, Millipore is unable to repair or replace the product or part, then Millipore shall refund to the customer all monies paid for such applicable product or part. MILLI-PORE SHALL NOT BE LIABLE FOR CONSEQUENTIAL, INCI-DENTAL, SPECIAL OR ANY OTHER INDIRECT DAMAGES RESULTING FROM ECONOMIC LOSS OR PROPERTY DAM-AGE SUSTAINED BY ANY CUSTOMER FROM THE USE OF ITS PRODUCTS.。

The life science business of Merck operates as MilliporeSigma in the U.S. and Canada.The Microfil ® filtration system is a simple and reliable solution for routine testing of raw materials, beverages and water for microbiological contamination. These tests are an important part of your quality assurance program. The standard testing method used in laboratories around the world for microbial analysis of fluids is membrane filtration. However, this method is technically demanding and requires time-consuming preparation, assembly and sterilization of the test apparatus.With our Microfil ® filtration system, you will eliminate time-consuming steps, equipment setup, waste, and autoclaving while improving the productivity of your lab. This cost-effective system uses presterilized, ready-to-use funnels and membranes on a filtration support.Benefits• No Preparation • No Washing • No Autoclaving • No Clamps • No Breakage • No Filter Wrinkling • No sample By-PassData SheetMicrofil ® Filtration SystemAn easy to use, fast and accurate system for the routine microbiological analysis of your beverages and drinking waterCulture MediaYou will find the full range of culture media (including broth and dehydrated media) on our website at /Microbiology.2Consistent RecoveriesUnlike with conventional filter holders, incompletesealing at the membrane/funnel interface is eliminated resulting in uniform recovery of organisms. The smooth hydrophobic funnel surface repels sample residues and microorganisms to ensure that any microorganisms in your sample are collected on the membrane and not lost on the funnels walls. Pleating and distortion of the wet membrane due to expansion is avoided by the design of the support. As a result, uniform contact between the membrane and the medium is achieved.Faster Filtration RatesDue to the membrane support, filtration rates withthe Microfil ® filtration system are faster when compared to traditional filtration equipment.Minimize Clean-Up, Assembly and AutoclavingReady-to-use, ultra-thin 100 or 250 mL Microfil ® funnels eliminate the need for washing and sterilizing after each test and make equipment handling easy. Packaged in convenient stacks of 25 or 30, the funnels are removed as needed from the custom designed funnel dispenser. Such vertical stacking of the funnels also optimizes lab space.A range of pre-sterilized 47 mm diameter gridded membranes are available with the Microfil ® funnels. Each membrane is individually sealed in pleated band (EZ-Pak ® membranes) or in peel back envelopes (S-Pak ® membranes). Polycarbonate membranes are also available.Easy-to-Use with No Clamps and No O-RingsThe push-fit design of the Microfil ® funnels seals tightly to manifold supports without the need for clamps or O-rings. This ensures leak-free operation and uniform microorganism recoveries.3Microfil ® Filtration System Method Advantages• Use of 47 mm gridded presterilized membranes • 100 mL and 250 mL funnels for drinking water and mineral water analysis• Hydrophobic funnel surfaces for improved recovery • Smooth interior funnel surfaces with no scratches • Lip seal to prevent membrane by-pass• Food-contact-polymer funnels, free from agents that may inhibit bacterial growth • Disposable funnels eliminate decontamination by flaming or use of alcohol • Recyclable plastic funnel material that allows for greater environmental protection • 0.45 μm membranes are certified in accordance with Standard Methods for coliform analysisUnited States• Standard Methods for the Examination of Water and Wastewater 22 edition, 2012Europe• EEC Directive 2009/54/EC of the European Parliament and of the council of 18th June 2009• EC Directive 98/83/EC, 3 November, 1998, amended version EEC directive 2015/178, relating to the quality of water intended for human consumptionWorldwideWHO Guidelines for Drinking Water Quality, 2017ISO ® RegulationsISO ® ISO 11731:2017: Water Quality Water Quality - Enumeration of Legionella ISO ® 8199:2018: Water Quality Water quality – General guidance on the enumeration of microorganisms by culture ISO ® 7899-2:2000: Water QualityDetection and enumeration of intestinalenterococci – Part 2: Membrane filtration methodISO ® 9308-1:2014: Water QualityEnumeration of Escherichia coli and coliform bacteria - Part 1: Membrane filtration method for waters with low bacterial background flora ISO ® 19250:2010: Water Quality Detection of Salmonella spp.ISO ® 26461-2:1986: Water Quality Detection and enumeration of the spores of sulfite-reducing anaerobes (clostridia); Part 2: Method by membrane filtration ISO ® 7704:1985: Water Quality Evolution of membrane filters used for microbiological analysesISO ® 16266:2006: Water QualityDetection and enumeration of Pseudomonas aeruginosa by membrane filtration ISO ® 14189:2013: Water Quality Enumeration of Clostridium Perfringens – Method using membrane filtration ISO ® 17995:2005: Water QualityDetection and enumeration of thermotolerant Campylobacter speciesRegulatory RequirementsThe Microfil ® filtration system method has been established with reference to InternationalStandards allowing biological analysis to be conducted under optimum conditions and conforms to International Standards for drinking water and mineral water.4Processing an aqueous sample using theMicrofil ®filtration system can be done in 7 simple steps:Step 2Place either an EZ-Pak ®, S-Pak ® or a polycarbonate membrane filter on the Microfil ® filtration system support.Step 3Dispense a Microfil ® funnel using the specially designed dispenser.Step 4Place the Microfil ® funnel on the support and push down to fix it firmly in place.Step 5Pour the sample into the funnel and filterby applying vacuum.Step 1Sanitize the Microfil ® filtration system support prior to processing each sample. Recommended methods include the use of alcohol or a quick flaming of the Microfil ® filtration system support steel surface.5Step 6Remove the funnel. The tweezer is stopped by a protective rim to avoid touching the filtration area.Step 7Place the membrane filter into a Petri dishcontaining solid or liquid medium and incubate.Step 8Filter support can easly be removedfor decontamination.Ordering Information150 Funnels and 150 S-Pak® MembranesEach box contains 6 x 25 (100 mL) or 5 x 30 (250 mL) sterilized Microfil® funnels and150 individually packed, sterilized 47 mm diameter gridded S-Pak® membranes, available with the following pore sizes and colors:0.2 µm white, gridded MIGSWG100MIGSWG250 0.45 µm white, gridded MIHAWG100MIHAWG250 0.45 µm white, plain MIHVWP100N/A0.45 µm black, gridded MIHABG100MIHABG250 0.7 µm white, gridded MIHCWG100MIHCWG2500.8 µm white, gridded MIAAWG100MIAAWG2501.2 µm white, gridded MIRAWG100MIRAWG250 150 Funnels and 150 Isopore® Polycarbonate Membranes0.4 μm; colorless, plain N/A MIHTTP250 Additional membranes are available - 0.4 μm; colorless, plain - 150 units - item MIHTTPMNE 150 Funnels and 150 EZ-Pak® MembranesEach box contains 6 x 25 (100 mL) or 5 x 30 (250 mL) sterilized Microfil® funnels anda band of 150 individually packed, sterilized 47 mm diameter gridded EZ-Pak® membranes, available with the following pore sizes and colors:0.2 µm white gridded MZGSWG101N/A0.45 µm white, gridded MZHAWG101MZHAWG251 0.45 µm black, gridded MZHABG101MZHABG251 0.8 µm white, gridded MZAAWG101MZAAWG251 0.8 µm black, gridded MZAABG101N/A6EquipmentEZ-Fit™ Manifold 1-place for Microfil®EZFITMIC01EZ-Fit™ Manifold 3-place for Microfil®EZFITMIC03EZ-Fit™ Manifold 6-place for Microfil®EZFITMIC06Microfil® Funnel Dispenser, for use with 100 mL funnels MIACFD101Microfil® Funnel Dispenser, for use with 250 mL funnels MIACFD201EZ-Pak® Dispenser Curve EZCURVE01EZ-Stream® Vacuum Pump for Liquid Transfer EZSTREAM1Microfil® filtration system pump head for Merck vacuum pump MCLHEAD01Petri Dishes47 mm Petri Dishes, packed in sleeves of 25 dishes. Available with or without cellulose pad.Petri Dish without pad150PD2004700Petri Dish without pad600PD2004705Petri Dish with pad150PD20047S0Petri Dish with pad600PD20047S510 canisters of 100 absorbent pads1000AP10045S01 pad dispenser and2 pad canisters200 pads & 1 dispenser AP10045S10.45 μm with MCE membrane absorbent pads in canister600 HAWG674SP HAWG674SPWe provide information and advice to our customers on application technologies andregulatory matters to the best of our knowledge and ability, but without obligation orliability. Existing laws and regulations are to be observed in all cases by our customers.This also applies in respect to any rights of third parties. Our information and advicedo not relieve our customers of their own responsibility for checking the suitabilityof our products for the envisaged purpose.For more information, please visit/EZ7Merck KGaAFrankfurter Strasse 250 64293 Darmstadt, GermanyDS1047ENEU Ver. 4.03039906/2020© 2020 Merck KGaA, Darmstadt, Germany and/or its affiliates. All Rights Reserved. Merck, the vibrant M, EZ-Fit, EZ-Pak, EZ-Stream, Microfil, Millipore and S-Pak are trademarks of Merck KGaA, Darmstadt, Germany or its affiliates. All other trademarks are the property of their respective owners. Detailed information on trademarks is available via publicly accessible resources.To place an order or receive technical assistanceOrder/Customer Service: /order Technical Service: /techserviceSafety-related Information: /safetycenter /Microfil。

平板膜运行维护手册检查跨膜压差的稳定性。

跨膜压差的突然上升表明膜污染的发生，这可能是不正常的曝气状态或污泥性质的恶化导致的。

这种情况发生时需采取必要的措施，例如膜组件的化学清洗。

（2）曝气状态检查曝气空气量是否为标准量、以及是否为均一曝气。

发现曝气空气量异常、有明显的曝气不均一时，请进行必要的措施：如通过空气冲刷管调节，检查安装情况以及调整曝气等。

（3）活性污泥的颜色及气味正常的活性污泥的颜色及气味为土褐色有凝集性、无令人不快的气味。

如果外观及气味不是这种状态时，请适当地对MLSS、DO、pH、水温、BOD负荷等数值进行检查。

（4）MLSS正常的MLSS在8000～10000mg/L。

没有满足该条件的场合，可能无法达到既定性能，因此请适当地调整MLSS范围：MLSS过低时，可采用投入种泥或停止污泥排放等措施；MLSS过高时，可采取增加通向污泥浓缩停留池等的污泥排放量等措施。

（5）DO正常的DO是膜生物反应器内均为2mg/L以上。

没有满足该条件时，可采取调整曝气条件等必要的措施。

（6）pH正常的pH为6～8。

没有满足该条件的场合，可能会发生无法达到既定性能的情况，请在预处理池中添加酸或碱来调整pH。

（7）水温正常的水温为15～35 ℃。

没有满足该条件的场合，可能会发生无法达到既定性能的情况，因此如有可能请采取冷却、保温等必要措施。

（8）水位请检查膜生物反应器的水位是否在正常范围内。

发生异常时请进行以下检查：可通过自动控制检查。

（9）出水色度微生物在死亡后，会分泌一种带有色素的惰性物质，从而导致出水颜色略黄。

此时，需排掉一些死泥，恢复出水颜色。

二、平板膜组件的初运行1、清水运行（1）检查和设置清水运行前，请先进行以下检查准备工作。

（a）请再次确认空气管、污水管的正确连接。

（b）确认膜元件箱体在曝气箱上已固定好。

（c）确认膜组件放置的反应池内已清洗完毕。

打开保护盖。

泥土和灰尘可能会对损坏膜组件。

（d）将清水放入池内之前，打开空气排放阀，排出膜元件中的空气。

Millipore Express ®SHC Hydrophilic FiltersHigh capacity, sterilizing-grade PES filtersMillipore Express ® SHC (Sterile, High Capacity) filters provide superior throughput and capacity in applications where sterilizing-grade performance is needed and premature filter plugging is aconcern. These filters are ideal for sterile filtration of cell culture media, protein solutions and other high fouling fluids. Millipore Express ® SHC filters contain two polyethersulfone membrane layers, 0.5 μm/0.2 μm, and come in a range of device formats and sizes to suit your application needs.Benefits• High capacity, high flux hydrophilic PES membranes • Validated sterilizing-grade performance • Easy wetting and integrity testing• Superior throughput in high fouling streams, including media and protein containing solutions • Increased capacity for improved process efficiency and economy • Broad chemical compatibility across a wide pH range (1-14) — caustic compatibleApplications• Media additives • Column protection• Concentrated protein streams • Cell harvest (post clarification)• Caustics/pH adjusters • Buffers • CIP solutionsFilter formatsMillipore Express ® SHC filters are offered in a range of filter formats and capsule sizes, and allow easy scale-up of your small volume filtration steps to larger , full-scale filtration processes.• OptiScale ® small-scale disposable capsule filters • Opticap ® XL 150/300/600 small-scale disposable capsule filters with optional filling bell— gamma compatible or presterilized • Opticap ® XL disposable capsule filters— autoclavable, gamma compatible, or presterilized • Opticap ® XLT disposable capsule filters— autoclavable, gamma compatible, or presterilized. Gamma compatible XLT capsules are also available in high area formats.• Standard and high area cartridge filtersData SheetThe life science business of Merck operates as MilliporeSigma in the U.S. and Canada.2Fewer filter change outs and extended capacityMillipore Express ® SHC filters are designed to maximize the capacity of constrained filtration systems. With its high flux and superior capacity, you can double your output without significant capital expense (see figures 1 and 2).Figure 1.CHO Cell Culture Growth Media: No PrefiltrationFigure 2.Protein Concentrate Post UltrafiltrationMobius ® Single-use SolutionsMillipore Express ® SHC hydrophilic filters are part of the Mobius ® integrated, disposable bioprocess solution. No matter what your application step, Mobius ®gamma-compatible turnkey assemblies, Mobius ® solutions provide faster turnaround time and reliable performance, right out of the box.OptiScale ® disposable capsule filtersOptiScale ® Process Development Screening ToolOptiScale ® disposable capsule filters provide a convenient small volume option for process screening and scaling. These “drop in” filters are faster and easier to set up than conventional 25 mm and 47 mm discs, and completely disposable. OptiScale ® capsule filters offer speed-to-market strategies for efficiently developing compounds and biotherapeutics.3Opticap ®XLT filtersOpticap ® XL 150, 300, and 600 capsules,shown with optional filling bell attachmentMillipore Express ®SHC cartridge filtersMillipore Express ® High Area (left) compared to Standard Area (right) Cartridge FiltersOpticap ® XL and XLT Disposable Capsule FiltersConvenient and easy-to-useOpticap ® XL and XLT’s capsule design allowsunparalleled hydraulic stress resistance in a disposable filter and eliminates the time and expense associated with stainless steel housings.Adjustable, easy-to-turn, upstream vents and drain valves with O-ring seals and hose barb connections allow for easy process control. Other ease-of-use features include flow direction arrows and a ribbed housing for easy gripping even with gloved hands.Additionally, the Opticap ® XL 150, 300 and 600 devices have the option to add a filling bell to protect an open container from airborne particles.Opticap ® XL Capsule FiltersOpticap ® XL disposable capsule filters have a unique capsule design that minimizes hold-up volume and reduces production losses. Opticap ® XL 150, 300, 600, 3, 5 and 10 capsules are available with Millipore Express ® SHC membranes in autoclavable, sterile and gamma compatible formats.Opticap ® XLT 10, 20 and 30 Capsule FiltersOpticap ® XLT disposable T-line capsule filters withMillipore Express ® SHC membrane are available with or without a pressure gauge port for ease in monitoring process conditions. The T-line design accommodates series or parallel filtration to match your application needs, and a specially-designed stand enables quick and easy integration into your existing process.10-, 20- and 30-inch Opticap ® XLT gamma compatible capsules are also available, with 2x the membrane area of the standard area capsules for increased capacity.Cartridge FiltersMillipore Express ® SHC 5-, 10-, 20- and 30-inch standard area cartridge filters provide fast flow rates and extended throughput and are designed to withstand multiple steam-in-place cycles. 10-, 20- and 30-inch cartridges are also available in formats with 2x the membrane area of the standard area cartridges. Each cartridge is integrity tested during manufacturing. Code 0 and code 7 O-ring adaptors are available to suit your applicationand housing needs.®456Typical Clean Water Flow RatesStandard Area Cartridge Filters with 0.5/0.2 µm Millipore Express ® SHC MembranesOpticap ® XL 3 Capsules with 0.5/0.2 µm Millipore Express ® SHC MembraneOpticap ® XLT 10 Capsules with 0.5/0.2 µm Millipore Express ® SHC MembraneHigh Area Cartridge Filters with 0.5/0.2 µm Millipore Express ® SHC MembranesOpticap ® XL 5 Capsules with 0.5/0.2 µm Millipore Express ® SHC MembraneOpticap ® XLT 20 Capsules with 0.5/0.2 µm Millipore Express ® SHC MembraneOpticap ® XL 10 Capsules with 0.5/0.2 µm Millipore Express ® SHC MembraneOpticap ® XLT 30 Capsules with 0.5/0.2 µm Millipore Express ® SHC MembraneOpticap ® XL Capsule Legends Refer to Connection Type TT = 38 mm (1½ in.) sanitary flange inlet and outlet HH = 14 mm (9/16 in.) hose barb inlet and outletTH = 38 mm (1½ in.) sanitary flange inlet and 14 mm (9/16 in.)hose barb outlet TB = 38 mm (1½ in.) sanitary flange inlet and 25 mm (1 in.)hose barb outletOpticap ® XLT Capsule Legends Refer to Connection Type TT = 38 mm (1½ in.) sanitary flange inlet and outletTH = 38 mm (1½ in.) sanitary flange Inlet and 16 mm (5/8 in.)hose barb outlet HH = 16 mm (5/8 in.) hose barb inlet and outletTB = 38 mm (1½ in.) sanitary flange inlet and 25 mm (1 in.)hose barb outlet BB = 25 mm (1 in.) hose barb inlet and outletOpticap ® XL and XLT Disposable Capsules (Autoclavable Only)®*Cage, end caps and capsule housing7®*Cage, end caps and capsule housingOpticap® XL 150 Capsules with 0.5/0.2 µm Millipore Express®Opticap® XL 300 Capsules with 0.5/0.2 µm Millipore Express®Opticap® XL 600 Capsules with 0.5/0.2 µm Millipore Express®Typical Clean Water Flow RatesOpticap® XL Capsule Legends Refer to Connection TypeFF:19 mm (3/4 in.) sanitaryflange inlet and outletFH:19 mm (3/4 in.) sanitaryflange inlet and 14 mm (9/16in.) hose barb outletHH:14 mm (9/16 in.) hose barb inlet and outlet8®*Cage, end caps and capsule housing**Only available in gamma compatible capsules910Typical Clean Water Flow RatesOpticap ® XL and XLT Disposable Capsules (Sterile and Gamma Compatible)Opticap ® XL 3 Capsules with 0.5/0.2 µm Millipore Express ® SHC MembraneStandard Area Opticap ® XLT 10 Capsules with 0.5/0.2 µm Millipore Express ® SHC MembraneHigh Area Opticap ® XLT 10 Capsules with 0.5/0.2 µm Millipore Express ® SHC MembraneOpticap ® XL 5 Capsules with 0.5/0.2 µm Millipore Express ® SHC MembraneStandard Area Opticap ® XLT 20 Capsules with 0.5/0.2 µm Millipore Express ® SHC MembraneHigh Area Opticap ® XLT 20 Capsules with 0.5/0.2 µm Millipore Express ® SHC MembraneOpticap ® XL 10 Capsules with 0.5/0.2 µm Millipore Express ® SHC MembraneStandard Area Opticap ® XLT 30 Capsules with 0.5/0.2 µm Millipore Express ® SHC MembraneHigh Area Opticap ® XLT 30 Capsules with 0.5/0.2 µm Millipore Express ® SHC MembraneOpticap ® XL Capsule Legends Refer to Connection Type FF = 19 mm (¾ in.) sanitary flange inlet and outletFH = 19 mm (¾ in.) sanitary flange inlet and 14 mm (9/16 in.)hose barb outlet TT = 38 mm (1½ in.) sanitary flange inlet and outlet HH = 14 mm (9/16 in.) hose barb inlet and outletTH = 38 mm (1½ in.) sanitary flange inlet and 14 mm (9/16 in.)hose barb outlet TB = 38 mm (1½ in.) sanitary flange inlet and 25 mm (1 in.)hose barb outletOpticap ® XLT Capsule Legends Refer to Connection Type TT = 38 mm (1½ in.) sanitary flange inlet and outletTH = 38 mm (1½ in.) sanitary flange Inlet and 16 mm (5/8 in.)hose barb outlet HH = 16 mm (5/8 in.) hose barb inlet and outletTB = 38 mm (1½ in.) sanitary flange inlet and 25 mm (1 in.)hose barb outlet BB = 25 mm (1 in.) hose barb inlet and outlet11Connection TypeFF = 19 mm (3/4 in.) sanitary flange inlet and outlet FH = 19 mm (3/4 in.) sanitary flange inlet and14 mm (9/16 in.) hose barb outlet HH = 14 mm (9/16 in.) hose barb inlet and outlet HB = 14 mm (9/16 in.) hose barb inlet and14 mm (9/16 in.) hose barb outlet with bell FB = 19 mm (3/4 in.) sanitary flange inlet and14 mm (9/16 in.) hose barb outlet with bellOptiScale ® Capsule FiltersOptiScale ® Capsule FilterQuantity per pkg.For 25 mm disc: 6 = 6/pk For 47 mm disc: 3 = 3/pkMay be AutoclavedMembrane Type HGE = M illiporeExpress ® SHC 0.5/0.2 µmDisc Size (mm)25 = 25 mm 47 = 47 mmConnection Type For 25 mm disc:NB = Female Luer Lok ™ Inlet/Male Luer Lok ™ outlet For 47 mm disc:HH = 6 mm (1/4 in.) hose barb inlet and outletFF = 19 mm (3/4 in.) sanitary flange inlet and outlet FH = 19 mm (3/4 in.) sanitary flange inlet and6 mm (1/4 in.) hose barb outletSAH G E Opticap ® XL 150/300/600 Capsule FiltersOpticap ®Capsule FilterQuantity per pkg.1 = 1/pk (Opticap ® XL 150gamma compatible only)3 = 3/pkSterilization G = G amma Compatible S = SterileMembrane Type HGE = M illiporeExpress ® SHC 0.5/0.2 µmCapsule Size015 = Opticap ®XL 150003 = Opticap ® XL 300006 = Opticap ® XL 600KH G EOpticap ® XL Capsule FiltersOpticap ® XL Capsule FilterSterilization A = Autoclavable G = Gamma Compatible S = SterileMembrane Type HGE =M illiporeExpress ® SHC 0.5/0.2 µmQuantity per pkg.3 = 3/pk (Opticap ® XL3 only)1 = 1/pk (Opticap ® XL 5and XL 10 only)KH G ECapsule Size 03 = Opticap ® XL 305 = Opticap ® XL 510 = Opticap ® XL 10Connection TypeTT = 38 mm (11/2 in.) sanitary flange inlet and outlet HH = 14 mm (9/16 in.) hose barb inlet and outlet TH = 38 mm (11/2 in.) sanitary flange inlet and14 mm (9/16 in.) hose barb outlet TB = 38 mm (11/2 in.) sanitary flange inlet and25 mm (1 in.) hose barb outletLit No. DS1428EN00 Ver . 10005163/2017Connection TypeTT = 38 mm (1½ in.) sanitary flange inlet and outlet HH = 16 mm (5/8 in.) hose barb inlet and outlet TH = 38 mm (1½ in.) sanitary flange inlet and16 mm (5/8 in.) hose barb outlet TB = 38 mm (1½ in.) sanitary flange inlet and25 mm (1 in.) hose barb outlet BB = 25 mm (1 in.) hose barb inlet and outletOpticap ® XLT FiltersOpticap ® XLT Capsule FilterSterilizationA = Autoclavable G = Gamma Compatible S = SterileCapsule Size 1 = O pticap ®XLT 102 = Opticap ® XLT 203 = Opticap ® XLT 30T-line Capsulewithout Gauge PortMembrane TypeHGE = M illiporeExpress ® SHC0.5/0.2 µmQuantity per pkg.1 = 1/pkArea TypeH= High Area (onlyavailable in gammacompatible Opticap ® XLT capsules with TT and TB connection types)K1TH G ECartridge FiltersCartridge FilterCartridge Code 0 = (2-222) O-ring 7 = (2-226) O-ring w/locking tab spearCartridge Length 5 = 5-inch(Code 7 only)1 = 10-inch 2 = 20-inch 3 = 30-inchO-ring Material S = Silicone E = EPDMF = FluoroelastomerArea Type T = Standard Area H = H igh Area (10-,20- and 30-inch cartridges only)Membrane Type HGE = M illiporeExpress ® SHC 0.5/0.2 µmQuantity per pkg.1 = 1/pk (10-inchCode 7 only)3 = 3/pkCH G E*Not all product configurations available; please call your EMD Millipore representative to confirm availability. The user guides for these products – Filters with Millipore Express ® Membrane Wetting Instructions, Integrity Testing, Sterilizing and DryingGuidelines - UG4224EN00 and Opticap ® XL Capsules and Opticap ® XLT Capsules User Guide - UG1011EN00, are available on our website.The life science business of Merck operates as MilliporeSigma in the U.S. and Canada. MilliporeSigma, Millipore Express, Mobius, Opticap, OptiScale and the Vibrant M are trademarks of Merck KGaA, Darmstadt, Germany. ASTM is a trademark of American Society for Testing and Materials. ISO is a registered trademark of the International Organization for Standardization. ATCC is a trademark of American Type Culture Collection. Luer-Lok is a trademark of Becton, Dickinson and Company. Copyright © 2017 Merck KGaA. All Rights Reserved.To place an order or receive technical assistanceIn Europe, please call Customer Service:France: 0825 045 645Germany************Italy: 848 845 645Spain: 901 516 645 Option 1Switzerland: 0848 645 645UnitedKingdom************For other countries across Europe, please call: +44 (0) 115 943 0840Or visit: /offices For Technical Service visit:/techservice。