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密执安大学药学院

密执安大学药学院
密执安大学药学院

密执安大学药学院

Pharmacy 401

Life Long Learning I .25 credits

The Life-Long Learning (IPPE/APPE) course promotes professional development, commitment to self-improvement, accountability for one’s learning as well as work and commitment to excellence. Over the course of the term, students are required to independently complete a variety of professional development IPPE activities. Independent study.

Pharmacy 402

Introduction to Pharmacy 2 credits

This course explores the profession of pharmacy and evolution of pharmacy. The course also evaluates and discusses the role of pharmacy as it relates to patient care, other health professionals, and the role in state and federal health care issues. Concept of professionalism will be explored and reflected upon during the course. Students have the opportunity to participate in different activities in the clinical setting and to engage with other health professionals.

Pharmacy 404

Community Pharmacy 2 credits

This course is the first in the pharmaceutical care series and focuses on interpretation of prescriptions, principles of compounding and dispensing of medications, pharmaceutical calculations, pharmacy management, top 50 medications, patient counseling, and introduction to manual blood pressure.

Pharmacy 406

Patient Communications 2 credits

Students will engage in activities reinforcing key communications skills, including patient interviewing and counseling. The role of cultural influences on communication of health information is explored. Students also work on these skills outside the classroom with a community partner. The skills learned in this course will be reinforced throughout the Pharm.D. curriculum. Two hours of lecture/discussion and 3 hours lab per week.

Medicinal Chemistry 415

Principles of Drug Action I 5 credits

This course introduces the concepts required to understand drugs as organic chemicals whose biological activities derive from their chemical structures and physicochemical properties/ The course includes a survey of specific drug classes, covering their structure activity relationship, mechanism of action and issues related to their clinical use.

Prerequisites: Chemistry 215, Biochemistry 415 and Physiology 502

Instructor: Beleh

Pharmacy 416

Pharmaceutical Care 1 credits

This course continues the process of developming skills needed for pharmaceutical care, including gathering information to complete a patient a patient database using the medication history, comprehensive drug therapy assessment, identification of medication related problems, creation of the pharmacist’s care plan, and enhancement of both written and verbal communication skills, focusing on communication with patients and other health care providers.

Prerequisites: Pharmacy 402, 404 and 406

Medicinal Chemistry 417

Principles of Drug Action II 5 credits

This course is a continuation of Medicinal Chemistry 415 and includes a survey of drugs acting on the central nervous system, hormones, vitamins, anti-inflammatory agents and steroids, covering their structure activity relationship, mechanism of action and other issues related to their pharmacology and clinical use.

Prerequisites: MedChem 415

Instructor: Staff

Medicinal Chemistry 419

Principles of Drug Action III 5 credits

This course is a continuation of Medicinal Chemistry 415 and 417 and includes a survey of antibiotics, antiviral and anticancer agents, pharmaceutical biotechnology and immunotherapy, covering structure activity relationship, mechanism of action and other issues related to the pharmacology and clinical use of related agents.

Prerequisites: MedChem 417

Instructor: Staff

Pharmacy 420

Pharmacy and the US Health Care Systems I 2 credits

The purpose of this course is to understand and analyze the various components of the United States Health care system with attention to the role of cost, access, pharmaceuticals, and the health care organization, government and health care professionals. This knowledge allows pharmacists to effectively navigate the health system for themselves, their patients, and society.

Instructor: Staff

Pharmacy 422

Health-System Pharmacy Practice, Leadership and Management 3 credits

This course is taught and assessed to establish best practices in health-system pharmacy and is designed to develop tomorrow's practitioners and leaders in health-system pharmacy practice. Class discussions and laboratory assignments will provide active learning opportunities for students to practice health-system skills and techniques.

Prerequisites: Second-year standing in PharmD program

Instructor: Staff

Pharmacy 426

Immunization Advocacy and Administration for Health Care Practioners 2 credits

This course is an interdisciplinary skills based elective course for pharmacy, nursing, and medical students. Through active participation in didactic community outreach projects, students engage in opportunities necessary for establishing an immunization service or clinic in various healthcare settings. Students receive a certificate of immunization training upon completion of the course.

Prerequisites: Second-year standing

Instructor: Staff

Pharmacy 430

Nonprescription Therapeutics and Self-Care 3 credits

This course is the first in a five-semester sequence on therapeutic problem solving, and emphasizes nonprescription therapies for the self-treating patient. Students learn a systematic approach to assessing, triaging and treating self-treatable conditions and about over-the-counter medications. Active learning strategies are employed.

Prerequisites: First year PharmD fall-term coursework

Pharmacy 431

Therapeutic Problem Solving I 3 credits

Second in a five-part sequence which integrates the pathophysiology and therapeutics of diseases. The focus is on drug therapy and applied pharmacokinetics of common chronic and acute conditions, including hypertension and diabetes. The role of evidence based medicine in regard to therapeutic decisions is emphasized and builds upon basic biological, pharmacological and pharmaceutical sciences. Developing pharmaceutical care plans that build skills on recommending therapy, evaluating and monitoring the efficacy and safety of medications for an individual patients is also emphasized.

Prerequisites: MedChem 415 and concurrent with MedChem 417 and PharmSci 464 Instructor: Staff

Pharmacy 432

Therapeutic Problem Solving II 3 credits

Third of a five-part course sequence which integrates the pathophysiology and therapeutics of diseases. The focus is on drug therapy and applied pharmacokinetics of common and acute conditions in areas such as women's health and pediatrics among others. Class time is devoted to discussion and a laboratory. A team based interactive approach to teaching is an essential part of the course series. Since class time is devoted to discussion and a lab, it is essential that students come prepared for class. Outside classroom assignments will be an essential component of the course.

Prerequisites: MedChem 417 and Pharmacy 431 and concurrent with MedChem 419 Instructor: Staff

Social and Administrative Sciences 445

Special Topics in Pharmacy Administration 2 credits

In-depth study of selected topics in pharmacy administration. Two hours a week.

Instructor: Staff

Pharmaceutical Sciences 462

Introduction to Drug Delivery 3 credits

Basic principles of drug delivery are developed with respect to identifying and characterizing biological and physical-chemical barriers to the bioavailability of drugs. Routes of drug delivery and related dosage forms are also introduced. Specific emphasis is placed on building principles and solving problems in equilibria, transport, and chemical kinetics of drug solutions as they relate

to liquid dosage form performance.

Prerequisites: Chemistry 216 and Physics 216

Instructor: Staff

Pharmaceutical Sciences 463

Drug Delivery and Drugs in Dispersed Systems and Solid Forms 3 credits

Course content includes the formulation, development and approval process of dosage forms comprised of disperesed phases (suspensions and emusions) and solid phases (amorphous and crystalline). The course integrates physicochemical and concepts with quality and performance of topical, oral and inhalation dosage forms.

Prerequisites: Pharmaceutical Sciences 462

Instructor: Rodriguez

Pharmaceutical Sciences 464

Pharmacokinetic Concepts and Applications 4 credits

This course is the third of four required courses in the pharmaceutical sciences curriculum. Course content includes the absorption, distribution, metabolism, and excretion of drugs and drug-related species by the body. Emphasis is placed on the use (not the derivation) of pharmacokinetic/dynamic models and equations. Additional emphasis is placed on designing suitable dosage regimens for the treatment and prevention of disease in humans. Three lecture hours and one discussion hour a week.

Prerequisites: Pharmaceutical Sciences 463

Instructor: Smith and staff

Pharmacy 476

Principles of Research and Problem Solving 2 credits

This is an introductory course in research methods and proposal writing. The course is designed to give students experience in hypothesis and specific aims development and an overview of scientific study design. The course objectives will be accomplished through didactic lecture and small group and individual assignments. Ultimately, each student will write a brief research proposal that follows a similar format to the PharmD Investigations proposal. In addition, students will present their research idea to peers in a poster/abstract format.

Instructor: Staff

Medicinal Chemistry 501

Chemical Biology I 3 credits

This course provides a high-level overview on the structure, function and chemistry of biological macromolecules including proteins, nucleic acids and carbohydrates. Topics include: molecular forces, structure, and dynamics: understanding macromolecular folding, energetics of macromolecular interactions (kinetics and thermodynamics), ligand binding and mechanistic enzymology. Using specific examples from current literature, each topic stresses how chemists have used molecular level tools and probes to help understand the specific systems under study. The overarching theme is that biological structure and function are interconnected.

Pharmacy 501

Life Long Learning 2 .25 credits

This course teaches the principles of drug information and literature evaluation using the concepts of evidence based practice. Skills include identifying resources to answer clinical questions, developing search strategies, and critically evaluating scientific literature allowing students to identify and utilize the best evidence to make decisions regarding patient care.

Instructor: Staff

Medicinal Chemistry 502

Chemical Biology II 3 credits

This course is a continuation of Chemical Biology 501. The basic concepts obtained in Chemical Biology 501 will be applied to and demonstrated in three broad areas of interest to both chemists and biologists. The first topic discusses protein homeostasis (both biosynthesis and degradation). The second topic focuses on signal transduction, emphasizing general concepts (at the molecular level) and how small molecules have been used to probe and modulate signal transduction pathways. The final topic covers chemical biology tools and approaches (selections, screens, small molecule libraries, genomics, proteomics, directed evolution and catalytic antibodies).

Prerequisites: Chemical Biology 501

Pharmacy 503 (formerly 425)

Service Learning for Health Professionals 1 credits

This service-based course explores issues of health disparities, poverty, and the medically-underserved through an inter-professional lens. The course is open to all health professions students. Students complete 20 hours of direct service to a health center or community agency and attend 7 class discussion sessions.

Instructor: Mason

Medicinal Chemistry 505

Exploring Pharmacy; Past, Present and Future 2 credits

A survey of the past, present and future of pharmacy in the context of drug discovery, including such topics as the history of pharmacy, pharmaceutical biotechnology and personalized medicine. The course examines the current state of global healthcare and its impact on drug discovery and the future of pharmacy.

Prerequisites: Third year Pharm.D. students or permission of instructor

Instructor: Beleh

Medicinal Chemistry 507

Biochemical Pharmacology of Cancer Chemotherapy 2 credits

A drug-oriented approach to cancer chemotherapy. Current research on established and developmental drugs is discussed, including experimental approaches to investigating drug metabolism and the cellular and biochemical mechanisms of action. Drugs discussed include antimetabolites (such as nucleosides and antifolates), mitotic blockers, and DNA-interactive agents.

Prerequisites: Biochemistry 415 or 580, Medicinal Chemistry 411 or 533

Instructor: staff

Pharmacy 515

Evidenced Based Medicine 2 credits

This course teaches the principles of drug information and literature evaluation using the concepts of evidence based practice. Skills include identifying resources to answer clinical questions, developing search strategies, and critically evaluating scientific literature allowing students to identify and utilize the best evidence to make decisions regarding patient care.

Instructor: Staff

Medicinal Chemistry 517

Drug Assay 3 credits

A capstone course for the Medicinal Chemistry/Pharmacology sequence through a survey of different drug classes and the various techniques used to assay their concentration in biological samples. The course provides hands-on experience of a number of laboratory techniques commonly used in drug analysis with an emphasis on data interpretation.

Prerequisites: MedChem 419

Instructor: Staff

Pharmaceutical Sciences 519

Pharmaceutical Engineering 3 credits

[Cross-listed with Chemical Engineering 519.] Offered in conjunction with the interdisciplinary Masters of Engineering in Pharmaceutical Engineering (M.Eng.) program, this course covers the concepts necessary to adapt engineering principles to pharmaceutical and life sciences related industries. Topics include process engineering in the drug discovery, high throughput characterization and optimization of new chemical entities, solid-state engineering, and intelligent pharmaceutical manufacturing systems. Lectures, problems, and Internet and library study will be used to develop the ideas presented.

Prerequisites: Senior or graduate standing, permission of instructor.

Pharmacy 522

Pharmacy Healthcare Outcomes 2 credits

The purpose of this course is to introduce concepts of effectiveness of pharmaceuticals to professional pharmacy students. The evaluation of effectiveness includes introduction of diverse topics such as drug utilization evaluation, pharmacoepdemiology, patient reported outcomes, medication error reduction, pharmaceutical policy/procedure development,health disparities, pharmacoeconomics, medication use-related database evaluation and basic concepts of Public health.

Prerequisites: Third Year Pharmacy Students

Instructor: Staff

Medicinal Chemistry 528

Protein Cofactors [cross-listed with Chemistry 528.] 2 credits

This course explores the roles of organic and organometallic cofactors in biology. Topics covered are cofactor assembly, cofactors as sensors, and cofactors in enzyme chemistry, with an emphasis

on modulation of cofactor reactivity by complexation with the protein.

Prerequisites: Biochemistry 452 or Chemistry 452, or equivalent, or permission of instructor Instructor: Matthews

Pharmacy 530

Pharmacy Law 1 credits

This course emphasizes the application of pertinent laws, rules, and regulations to the practice of pharmacy. Students will gain an understanding of the rules and regulations governing the practice of pharmacy through faculty lecture, classroom discussion, and assignments. Students will also learn where to find information regarding pharmacy law that they will continue to use through their professional life.

Prerequisites: Third Year Doctor of Pharmacy Student

Instructor: Staff

Pharmacy 531

Therapeutic Problem Solving III 3 credits

The focus of this course is on drug therapy and applied pharamcokinetics of common and acute conditions related to mental health, nephrology, and infectious diseases. The role of evidence based medicine in regard to therapeutic decisions is emphasized and builds upon basic biological, pharmacological and pharmaceutical sciences. Developing pharmaceutical care plans that build skills on recommending therapy, evaluating and monitoring the efficacy and safety of medications for individual patients is also emphasized.

Prerequisites: Pharmacy 432

Instructor: Staff

Medicinal Chemistry 532

Bioorganic Principles of Medicinal Chemistry 2 credits

A mechanistic organic chemistry/biochemistry approach to medicinal chemistry, emphasizing macromolecular targets of drug action. The first of six sections focuses on receptors and ligand-receptor interactions, stressing energetics and stereochemical considerations. Section two deals with enzymes as drug targets, with emphasis on inhibitors of enzyme action. Section three explores metabolic pathways and mechanisms for xenobiotic transformation. Section four discusses DNA as a target for drug action and includes agents that interact with DNA directly and those that inhibit its synthesis. Section five covers the rationale behind pro-drug approaches as well as design strategies based on routes of bioactivation. Section six is a brief overview of biotechnology approaches with important benefits for drug discovery.

Prerequisites: Chemistry 540, Biochemistry 550, or permission of instructor

Instructor: Garcia

Pharmacy 532

Therapeutic Problem Solving IV 3 credits

The last in a sequence of courses that integrate the pathophysiology and therapeutics of diseases. The focus is on drug therapy and applied pharmacokinetics of common and acute conditions related to oncology, rheumatology, hepatology, cardiology and others. The class includes

discussion sesssions and a laboratory. A team-based, interactive approach to teaching is an essential part of the course series. Since class time is devoted to discussion and a lab, it is essential that students come prepared for class. Outside classroom assignments are an essential component of the course.

Prerequisites: Pharmacy 531

Instructor: Staff

Medicinal Chemistry 533

Survey of Medicinal Chemistry 3 credits

Offered alternate Winter Terms. Will be offered Winter Term 2013. A general survey of therapeutic agents in principal use today, with emphasis on their origin, chemistry, and mechanisms of action. For students with a one year’s course in organic c hemistry. Three hours lecture a week.

Prerequisites: Medicinal Chemistry 532 or permission of instructor

Instructor: Staff

Medicinal Chemistry 534

Drug Discovery 3 credits

survey of methods used in contemporary pharmaceutical research including computational and combinatorial approaches, and high-throughput analysis of drug efficacy and metabolism.

Prerequisites: Medicinal Chemistry 532, or permission of instructor

Instructor: Carlson

Pharmacy 535

EBM/Ethics Clinical Application 1 credits

This course builds on the principles and skills taught in Pharmacy 515 regarding evidence based medicine. These skills and principles include drug information and literature evaluation, developing search strategies and critically evaluating scientific literature, applying the evidence in clinical practice, and exploring principals of ethics and ethical dilemmas that present challenges to the clinical practitioner.

Prerequisites: Third Year Pharmacy Students

Instructor: Staff

Pharmacy 545

EBM/Ethics Advanced Clinical Application 1 credits

This course continues to build on the principles and skills taught in Pharmacy 535 regarding ethics and evidence-based medicine. These skills and principles include drug information and literature evaluation, refining search strategies, critically evaluating scientific literature, applying evidence in clinical practice, and exploring principals of ethics and ethical dilemmas that present challenges to the practicing clinician.

Prerequisites: Third Year Doctor of Pharmacy Students

Instructor: Staff

Pharmacy 547

Pediatric Pharmacotherapy 2 credits

This course provides disease-oriented, pharmacy-oriented insight into the pathophysiology, diagnosis, and rational drug treatment of diseases primarily encountered in the pediatric age group. Emphasis is on the pharmacist’s role in selecting drug products, individualizing dosages, and monitoring patients. Two hours lecture, case discussion a week.

Prerequisites: Pharmacy 531

Instructor: Staff

Pharmacy 548

The Aging Patient 2 credits

Sensitization to health and social status of the elderly. The course is designed to facilitate successful interaction with the aged on personal and professional levels through discussion of: physiologic changes and normal and pathologic aging; important medical conditions most common among the aged; the impact of chronic illness; issues in death and dying; modifications in drug therapy for the aged person; and the role of the pharmacist in caring for the elderly. Two hours lecture a week.

Prerequisites: Third- and fourth-year Pharm.D., or graduate student standing

Instructor: Staff

Pharmacy 550

Opportunities in Pharmacy 2 credits

This course explores a variety of topics, including unique opportunities for pharmacists in industry, government, professional writing; the pros and cons of post-graduate training (fellowships, residencies, Ph.D., etc.); how to get the “perfect job”; job interview techniques; pros and cons of board certification; how to become professionally active; and balancing both professional and personal demands. Two hours of seminar/discussion a week.

Prerequisites: Third-year Pharm.D. students

Instructor: Staff

Pharmacy 551

Direct Patient Care Introductory Pharmacy Practice Experience 2 credits

This course builds upon the skills learned earlier in the Pharmaceutical Care series. It facilitates the development of pharmaceutical care skills through students' participation in patient care initiatives that contribute to the role of pharmacists in health care. Emphasis is on developing these skills: patient data collection, medication assessment, pharmaceutical care plans involving evidence-based recommendations, chart notes, case presentations, journal club, and written and verbal communications skills. Fours hours of direct patient care experience, and two hours of patient care discussion per week.

Prerequisites: Third Year Pharm.D. Students

Instructor: Staff

Pharmacy 552

Disease Management 1 credits

This course is designed to develop and enhance patient care skills in the management of the most common chronic disease states managed in the ambulatory care environment. Students will enrich

their patient care skills and core clinical communication skills through a combination of individual and group activities.

Prerequisites: Third Year Doctor of Pharmacy Student

Instructor: Staff

Pharmacy 554

Performance Enhancing Substance & The Athlete 2 credits

This course explores the use and abuse of substances to enhance athletic performance and, to a lesser extent, body image. Content includes the prevalence and epidemiology of substance use and in-depth topic discussions covering a variety of agents focused on evidence of efficacy/benefits, and medical and societal issues related to use of these substances.

Instructor: Chaffee

Pharmacy 561

Health Systems/Hospital IPPE 2 credits

This course is designed to enhance the pharmacy skills learned earlier in the program by providing hands-on experience dispensing medications, conducting drug therapy assessments, counseling patients about prescription medications, communicating with other health care practitioners, and completing special written projects or presentations. Eight hours per week of supervised supervised experiences in the hospital pharmacy setting.

Prerequisites: Third Year Pharm.D. Students

Instructor: Staff

Pharmacy 562

Community Introductory Pharmacy Practice Experience 2 credits

This course is designed to enhance pharmacy skills learned earlier in the program through hands-on experience dispensing medications, drug therapy assessments, counseling patients about presription and nonprescription medications, communicating with other health care professionals, and completing special written projects or presentations. Eight hours per week of supervised experience in a community pharmacy.

Prerequisites: Second Year Standing

Instructor: Staff

Pharmaceutical Sciences 563

Modern Biopharmaceutics and Pharmacogenomics 2 credits

A course in Modern Biopharmaceutics and the recent advances in Pharmacogenetics and Genomics. The course will cover the oral absorption and metabolism of drugs from a classical and modern molecular perspective including discussion of current FDA Bioequivalence (BE) regulatory standards. It will also cover the most recent advances in pharmacogenomic and genetic test methods particularly as they relate to the selectivity and variability, in patients, of drug toxicity and efficacy.

Prerequisites: PharmD Student or Permission of Instructor

Instructor: Staff

Medicinal Chemistry 565

Pharm.D. Investigations - Research Proposal 1 credits

The first in a sequence of courses needed to complete the PharmD Investigations requirement. This component of the series includes the written research proposal. A grade will be submitted upon the successful submison and final approval of the proposal by the PharmD Investigations Committee.

Prerequisites: Third-year standing

Instructor: Staff

Pharmaceutical Sciences 565

Pharm.D. Investigations - Research Proposal 1 credits

The first in a sequence of courses needed to complete the PharmD Investigations requirement. This component of the series includes the written research proposal. A grade will be submitted upon the successful submison and final approval of the proposal by the PharmD Investigations Committee.

Prerequisites: Third-year standing

Instructor: Staff

Pharmacy 565

Pharm.D. Investigations - Research Proposal 1 credits

The first in a sequence of courses needed to complete the PharmD Investigations requirement. This component of the series includes the written research proposal. A grade will be submitted upon the successful submison and final approval of the proposal by the PharmD Investigations Committee.

Prerequisites: Third-year standing

Instructor: Staff

Pharmacy 567

Introduction to Critical Care Pharmacotherapy 2 credits

This course provides a basic overview of key concepts in critical care. Course content includes the principles of hemodynamic monitoring and the pathophysiology and management of selected diseases affecting major organ systems and requiring intensive care therapy.

Prerequisites: Third-year standing

Instructor: Staff

Pharmaceutical Sciences 568

Investigations in Pharmaceutics 1-6 credits

Original investigation of a laboratory or library problem to be selected after consultation with the instructor. A paper is required.

Prerequisites: Permission of instructor

Instructor: Staff

Medicinal Chemistry 570

Research 1-6 credits

The experiences will vary depending on the specific faculty member's project but may include: conducting clinical or basic science research, performing an extensive review of the literature and preparing a summary report/manuscript, analyzing data that has previously been collected. Students may work on a single project or be exposed to several types of projects during the course. For specific details of the course, students should contact individual faculty.

Prerequisites: Pharm.D. students. Permission of instructor.

Instructor: Staff

Pharmaceutical Sciences 570

Research 1-6 credits

The experiences will vary depending on the specific faculty member's project but may include: conducting clinical or basic science research, performing an extensive review of the literature and preparing a summary report/manuscript, analyzing data that has previously been collected. Students may work on a single project or be exposed to several types of projects during the course. For specific details of the course, students should contact individual faculty.

Prerequisites: Pharm.D. students. Permission of instructor

Instructor: Staff

Pharmacy 570

Research 1-6 credits

The experiences will vary depending on the specific faculty member's project but may include: conducting clinical or basic science research, performing an extensive review of the literature and preparing a summary report/manuscript, analyzing data that has previously been collected. Students may work on a single project or be exposed to several types of projects during the course. For specific details of the course, students should contact individual faculty.

Prerequisites: Pharm.D. students. Permission of instructor

Instructor: Staff

Social and Administrative Sciences 570

Research 1-6 credits

The experiences will vary depending on the specific faculty member's project but may include: conducting clinical or basic science research, performing an extensive review of the literature and preparing a summary report/manuscript, analyzing data that has previously been collected. Students may work on a single project or be exposed to several types of projects during the course. For specific details of the course, students should contact individual faculty.

Prerequisites: Pharm.D. students. Permission of instructor

Instructor: Staff

Medicinal Chemistry 573

Investigations in Medicinal Chemistry 1-6 credits

Original investigation of a laboratory or library problem to be selected after consultation with the instructor. A paper is required.

Prerequisites: Permission of instructor

Instructor: Staff

Social and Administrative Sciences 574

Investigations in Pharmacy Administration 1-6 credits

Original investigation of a laboratory or library problem to be selected after consultation with the instructor. A paper is required.

Prerequisites: Permission of instructor

Instructor: Staff

Medicinal Chemistry 575

Pharm.D. Investigations - Research Data 2 credits

The second in a sequence of three courses needed for the PharmD Investigations requirement. This semester of the series is designed for students to obtain hands on experience in conducting their research and collecting and analyzing all research data. Students work under the supervision of their faculty mentor to develop data collection forms and methods to archive data in a way that facilitates their analysis.

Prerequisites: Medicinal Chemistry Pharm.D. Investigations - Research Propopsal Pharmaceutical Sciences 575

Pharm.D. Investigations - Research Data 2 credits

The second in a sequence of three courses needed for the PharmD Investigations requirement. This semester of the series is designed for students to obtain hands on experience in conducting their research and collecting and analyzing all research data. Students work under the supervision of their faculty mentor to develop data collection forms and methods to archive data in a way that facilitates their analysis.

Prerequisites: Pharmaceutical Sciences Pharm.D. Investigations - Research Proposal

Pharmacy 575

Pharm.D. Investigations - Research Data 2 credits

The second in a sequence of three courses needed for the PharmD Investigations requirement. This semester of the series is designed for students to obtain hands on experience in conducting their research and collecting and analyzing all research data. Students work under the supervision of their faculty mentor to develop data collection forms and methods to archive data in a way that facilitates their analysis.

Prerequisites: Pharmacy Pharm.D. Investigations - Research Proposal

Pharmacy 580

Special Topics 1-6 credits

An in-depth discussion of selected pharmacy- and medication-related issues. Students will be expected to provide in-class presentations and write a paper.

Instructor: Staff

Pharmaceutical Sciences 596

Pharmaceutical Engineering Seminar 1 credits

Offered in conjunction with the interdisciplinary Master of Engineering (M.Eng.) in

Pharmaceutical Engineering program. The seminar features invited speakers from pharmaceutical and life science-related industries and academic institutions.

Prerequisites: [Cross-listed with Chemical Engineering 596.]

Instructor: Wang

Pharmacy 597

Regulatory Issues for Scientists, Engineers, and Managers 2 credits

Science- and technology-based rationale behind various regulatory issues involved in pharmaceutical and related industries.

Instructor: Staff

Pharmacy 601

Life Long Learning 3 .25 credits

The third course in a series of professional development courses, following Pharmacy 401 and Pharmacy 501.

Prerequisites: Third Year Pharmacy Students

Instructor: Staff

Pharmacy 602

Drug Development and Randomized Clinical Trials 2 credits

Seminars on drug discovery, protocol design, adverse events, safety issues, and setting up a drug study.

Prerequisites: Cross-listed with Internal Medicine 602

Instructor: Staff

Medicinal Chemistry 608

Topics in Cancer Chemotherapy 2 credits

This course introduces a study of how basic biological mechanisms have aided in the design and use of cancer chemotherapeutic agents. The chemistry and biochemical pharmacology of the various classes of agents are considered in detail. Two hours lecture a week.

Prerequisites: Medicinal Chemistry 411 or Medicinal Chemistry 533.

Instructor: Staff

Pharmacy 620

Pharmacotherapeutics I 3 credits

Prerequisites: Graduate standing in the School of Nursing or permission of instructor Instructor: Staff

Medicinal Chemistry 621

Translational Pharmacology: From Drug Discovery to Therapeutics 2 credits

Cross Listed with Pharmacology 621 Experts from academica and industry will take you on a journey from bench science to new therapeutic agents. Students will learn how to translate preclincial studies to clinical trials adn FDA approval. Critical evaluation of clinical trials, patent

issues and pharmacoeconomics will also be taught.

Prerequisites: Basic knowledge of opharmacologic principles and permission of instructor Instructor: Staff

Pharmacy 621

Pharmacotherapeutics II 3 credits

Prerequisites: Graduate standing in the School of Nursing or permission of instructor. Instructor: Staff

Medicinal Chemistry 625

Drug Discovery and Development: From Test Tube to Pharmacy Shelf 2 credits

An account of the various steps involved in taking a new drug from concept to pharmacy shelf. Covers discovery research, preclinical development, clinical research and operations, regulatory affairs, patents and trademarks, project management, and marketing. Guest speakers from industry give two-hour presentations.

Prerequisites: Third-year Pharm.D. or graduate student standing

Instructor: Staff

Medicinal Chemistry 635

Advanced Topics in Medicinal Chemistry 2 credits

Lectures and discussion on one or more topics of current investigational importance. Two hours lecture and discussion a week. For the Fall Term 2011: This course surveys the strategies and techniques used to transform biologically active molecules into potential therapeutic agents. Topics include: sources of molecular leads, structure-activity relationship analysis, improving pharmacokinetics and reducing toxicity. The course concludes with case histories of successful drug development illustrating the application of design principles taught in the class.

Prerequisites: Medicinal Chemistry 532 and 533 or permission of instructor

Instructor: Staff

Medicinal Chemistry 640

Short Course in Pharmacological Sciences 1 credits

This course, presented by the Medical School Department of Pharmacology, details a given area of pharmacological research. Guest speakers give two-hour presentations, the first hour of which is an introductory overview of a topic; the second, a more detailed presentation of current research in the area. Past topics have included opiate and opiate-related peptides and control of neurotransmitter release. Ten hours lecture a week.

Instructor: Staff

Medicinal Chemistry 660

Responsible Conduct of Research and Scholarship in Pharmaceutical Sciences at the University of Michigan 1 (half credit each term) credits

This course teaches students about ethics and integrity in science. It takes advantage of case studies that link basic principles with specific examples, providing students with opportunities to

discuss and develop concepts related to ethics and scientific integrity. A major teaching tool will be the use of case studies where students discuss model cases and are challenged to apply their own knowledge as well as their personal experiences and insights in order to derive appropriate solutions to the problems posed. This course is aimed at the predoctoral students at the College of Pharmacy.

Prerequisites: Graduate students at the College of Pharmacy, with permission of instructor Instructor: Woodard

Pharmacy 680

Pharm.D. Seminar 1 credits

A formal seminar is presented by each student to the fourth-year Pharm.D. class and selected faculty on topics ranging from patient case studies to the analysis of pharmacy practice problems. Each seminar topic is directed by a faculty preceptor and includes a question and answer period and discussion questions.

Prerequisites: Fourth-year Pharm.D. standing

Instructor: Staff

Pharmacy 687

Advanced Pharmacy Practice Experience 1 4 credits

Each of the eight required advanced pharmacy practice experiences provide five weeks of supervised pharmacy practice for at least 40 hours per week. The advanced pharmacy practice experiences are conducted in community, institutional, inpatient care, ambulatory care, drug information, and nontraditional care practice settings throughout southeast Michigan, or at select out-of-state sites. Students must show proof of a valid Michigan Pharmacist Educational Limited Internship License, a negative tuberculosis test, and complete a background check before the clerkship begins.

Prerequisites: Fourth-year standing and successful completion of Pharmacy 531 and 532 Instructor: Staff

Pharmacy 688

Advanced Pharmacy Practice Experience 2 4 credits

Prerequisites: Fourth-year standing

Instructor: Staff

Pharmacy 689

Advanced Pharmacy Practice Experience 3 4 credits

Prerequisites: Fourth-year standing

Instructor: Staff

Pharmacy 690

Advanced Pharmacy Practice Experience 4 4 credits

Prerequisites: Fourth-year standing

Instructor: Staff

Pharmacy 691

Advanced Pharmacy Practice Experience 5 4 credits

Prerequisites: Fourth-year standing

Instructor: Staff

Pharmacy 692

Advanced Pharmacy Practice Experience 6 4 credits

Prerequisites: Fourth-year standing

Instructor: Staff

Pharmacy 693

Advanced Pharmacy Practice Experience 7 4 credits

Prerequisites: Fourth-year standing

Instructor: Staff

Pharmacy 694

Advanced Pharmacy Practice Experience 8 4 credits

Prerequisites: Fourth-year standing

Instructor: Staff

Pharmacy 695

Advanced Pharmacy Practice Experience 9 4 credits

Prerequisites: Fourth-year standing

Instructor: Staff

Pharmaceutical Sciences 700

Biopharmaceutics and Drug Disposition 3 credits

This entry level course is designed for 1st or 2nd year graduate students in the pharmaceutical or related biomedical sciences. The course focuses on the ADME concepts of absorption, distribution, metabolism, excretion, and basic pharmacokinetic/dynamic modeling, along with transport, transporters, drug metabolism, and pharmacogenomics. One and one-half hour lectures are held twice a week.

Instructor: Smith and staff

Pharmaceutical Sciences 701

Pharmaceutical Design, Delivery and Targeting – Physical-Chemical Concepts 3 credits

This course focuses on the physical-chemical concepts of drug design, delivery and targeting. The fundamental principles of drug molecules in physical pharmacy, formulation, and drug delivery technologies are covered in this course.

Prerequisites: Graduate student standing

Instructor: Rodriguez

Pharmaceutical Sciences 702

Pharmaceutical Design, Delivery and Targeting – Biomolecular Concepts 3 credits

This course focuses on the biological and molecular concepts of drug design, delivery and targeting. The fundamental principles of cell biology and molecular biology will be applied to drug design, targeted drug delivery, and cellular drug delivery.

Prerequisites: Graduate student standing

Instructor: Lee

Pharmaceutical Sciences 703

Advanced Physicochemical Concepts of Drug Development and Delivery 3 credits

This course focuses on the advanced physicochemical and molecular concepts of drug development, formulation design, and drug delivery which follows from introductory concepts in PharmSci 701. The importance of solution chemistry, interfacial chemistry, and materials chemistry in pharmaceutical sciences will be presented.

Prerequisites: PharmSci 701, Math 216 or equivalent

Instructor: Schwendeman

Social and Administrative Sciences 710

Pharmacist Roles and Pharmaceutical Products 2 credits

This course addresses two key areas related to pharmacists and pharmaceutical products: (1) the roles and functions of pharmacists and pharmaceutical products; and (2) the regulation, distribution, and pricing of pharmaceutical products.

Prerequisites: Graduate students

Instructor: Gaither

Social and Administrative Sciences 720

Drug Utilization Review 2 credits

The first part of this course addresses quality assurance in the American health care delivery system, with particular focus on professional services. The second part examines a specialized quality assurance methodology, called drug utilization review, that focuses on the prescribing and use of prescription drug therapy.

Prerequisites: Graduate students

Instructor: Staff

Social and Administrative Sciences 722

Work-Related Attitudes and Behaviors of Pharmacists 2 credits

An in-depth analysis of the various social, organizational and psychological factors that influence job satisfaction, commitment, stress, turnover, etc. Course readings and discussions explore

related theories and concepts and how these theories and concepts influence pharmacists in the workplace. A course project is required.

Prerequisites: Graduate students and third-year Pharm.D. students

Instructor: Gaither

Social and Administrative Sciences 725

Managing the Medication Use System 2 credits

This course examines the medicine use system within the framework of continuous quality improvement. Students will gain familiarity with the basic concepts of quality improvement and learn how these concepts can be used to improve the quality of medication use in collaboration with patients, physicians, pharmacists, administrators and regulators.

Prerequisites: Graduate or third-year Pharm.D. students

Instructor: Staff

Social and Administrative Sciences 726

Pharmaceutical Health Services Research 2 credits

This course is an advanced-level seminar on the concepts, methods and problem areas addressed by pharmaceutical/health services research as a field of inquiry. The focus of the course is on the development and critique of a health services research proposal.

Prerequisites: Graduate student standing

Instructor: Balkrishnan

Medicinal Chemistry 740

Seminar in Medicinal Chemistry 1 credits

Presentation of topics from the original literature by students.

Prerequisites: Medicinal Chemistry 533 or equivalent

Instructor: Mosberg

Pharmaceutical Sciences 755

Advanced Topics in Pharmaceutics 2 credits

The application of recently developed concepts and techniques to pharmaceutical research.

Prerequisites: Chemistry 463.

Instructor: Staff

Pharmaceutical Sciences 760

Advanced Pharmacokinetics and Biopharmaceutics 3 credits

A continuation of the basic concepts introduced in PharmSci 464 or 700. The course emphasizes the derivation and use of pharmacokinetic and pharmacodynamic equations, methods of data analysis, and computer applications including the use of WinNonlin and NONMEM. One and one-half hour lectures are held twice a week.

Prerequisites: Math 216 (Differential Equations) and PharmSci 464 or 700 (Basic Pharmacokinetics); or permission of instructor. A course in statistics would be helpful. Instructor: Smith and staff

Social and Administrative Sciences 780

Advanced Topics in Social and Administrative Sciences 1-3 credits

An indepth discussion of selected pharmacy and medication related issues. Students will be expected to provide in-class presentations and/or write a paper.

Prerequisites: Graduate students or permission of instructor

Instructor: Staff

Medicinal Chemistry 799

Roundtable on Selected Topics in Medicinal Chemistry 1 credits

Topics researched by students and presented to a class of not more than 12 members. Group discussion is encouraged. Students may write critiques of presentations. One area of medicinal chemistry is covered each semester the course is taught. Pass/fail grading system.

Prerequisites: Medicinal Chemistry 532 and 533, Pharmacology 500, or permission of instructor Instructor: Staff

Pharmaceutical Sciences 838

Seminar in Pharmaceutics 1 credits

Reports on current studies in the field of pharmaceutics. May be elected by candidates for the master of science degree with permission of instructor but will not be credited toward the 28-hour minimum requirement for the degree. Satisfactory/unsatisfactory grading system.

Prerequisites: Graduate student standing or permission of instructor

Instructor: Staff

Pharmacy 839

Seminar in Pharmacy 1 credits

Reports on current studies in the field of pharmacy. May be elected by candidates for the M.S. degree with permission of the instructor, but will not be credited toward the 28-hour minimum requirement for this degree.

Instructor: Staff

Social and Administrative Sciences 839

Seminar in Social and Administrative Sciences 3 credits

Reports on current studies in social and administrative sciences in pharmacy.

Instructor: Staff

Medicinal Chemistry 840

Seminar in Medicinal Chemistry or in Pharmaceutical Analysis 1 credits

Reports on current studies in medicinal chemistry or pharmaceutical analysis.

Instructor: Staff

Social and Administrative Sciences 870

Research Methods in the Behavioral Sciences 3 credits

Advanced methods in behavioral research focusing on the use of structural equation models.

全文上海中医药大学教学实验中心

全文上海中医药大学教学实验中心 徐佳虞莉青夏延明赵影张馥晴 指导老师:陆雄 (上海中医药大学03针英七,上海202003) [摘要]目的:研究染发剂对幼年小白鼠肾功能的阻碍。方法:用市售染发剂给20只昆明种幼年小白鼠染毛(即实验组,雄鼠M1组n=10,雌鼠M2组n=10),另20只小鼠做空白对比(即正常组,雄鼠N1组n=10,雌鼠N2组n=10)。染毛第18天经摘眼球取血,测血肌酐和血清尿素氮,并取肾组织作肾脏病理切片观看。结果:外观上来看,M1组的脱毛现象较明显;数据显示,实验组的血肌酐明显低于正常组(P<0.05),有统计学意义。M2组的血清尿素氮明显高于N2(P<0.05),有统计学意义。而M1组与N1组的血清尿素氮比较无统计学差异(P>0.05)。形状学观看结果没有发觉病理形状学改变。结论:目前市售常用染发剂短期内能够导致雄性小鼠脱发觉象,但对雄性小鼠肾功能及肾组织形状没有明显的损害;对雌性小鼠,能够导致血清尿素氮的升高,但不阻碍血肌酐以及肾组织病理形状。提示短期染发毒性较轻微,其造成的毒性可能有性别差异。 [关键词]染发剂,幼年小白鼠,血肌酐,血清尿素氮,病理形状 爱美之心人皆有之。随着社会的进展,色彩丰富的染发剂已不再单用于遮盖白发,它成为了一种流行的象征,同时这一现象正更加趋向于年轻化。然而染发剂对人体的危害却不容我们忽视。染发剂要紧是由对苯二胺构成,据CCTV每周质量报告指出,这些有毒的化学品要紧通过皮肤毛囊进入血液到达骨髓对染发者造成肝、肾的损害,从而诱发各种癌症。目前可查研究差不多上局限于血液骨髓的破坏及部分癌症的研究,肾毒性的确切性研究尚无。因此,本实验旨在确定短期内染发剂对肾脏是否造成毒性反应。1.材料和方法 1.1 材料 1.1.1 实验动物:昆明刚断奶小白鼠共40只,平均体重为9.8g,雌雄各半,随机分为染发剂组(即实验组,M1组雄鼠10只,M2组雌鼠10只),以及正常对比组(N1组雄鼠10只,N2组雌鼠10只)。实验动物均由上海中医药大学动物实验中心提供。(批号SCXK(沪)2003-0003 上海斯莱克实验动物) 1.1.2染发剂:市售常用氧化型染发剂二种颜色(随机选为:红色和黑色),染发剂均购自超市。(批号768128-D,上海章华保健化妆品,卫妆特字(2003)第0728号) 1.1.3 实验器材:刷子、弯镊、剪刀、镊子、微量吸管 TGL-16G台式高速离心机(上海医用分析仪器厂) TP1020自动脱水机(德国Leica公司)

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药学专业考研院校排名 ①:100706药理学 B+ 等 ( 24 个 ) :河北医科大学(石家庄)、吉林大学(长春)、广西医科大学(南宁)、山东大学(济南)、福建医科大学(福州)、新疆医科大学(乌鲁木齐)、西安交通大学(西安)、南京大学(南京)、苏州大学(苏州)、暨南大学(广州)、武汉大学(武汉)、天津医科大学(天津)、清华大学(北京)、兰州大学(兰州)、郑州大学(郑州)、温州医学院(温州)、汕头大学(汕头)、南京中医药大学(南京)、石河子大学(新疆石河子)、上海中医药大学(上海)、南华大学(湖南衡阳)、烟台大学(山东烟台)、首都医科大学(北京)、昆明医学院(云南昆明) ②:100704药物分析 B+ 等 ( 14 个 ) :华中科技大学、西安交通大学、山东大学、湖南师范大学、天津大学、福州大学、中山大学、山西医科大学、吉林大学、兰州大学、天津医科大学、上海交通大学、河北医科大学

③:100702药剂学 B+等级(12个):华中科技大学、浙江中医药大学、哈尔滨医科大学、南方医科大学(广州)、中南大学(湖南长沙)、西安交通大学、贵阳医学院(贵州贵阳)、广东药学院(广东湛江)、上海中医药大学、天津大学、安徽中医学院(安徽合肥)、成都中医药大学(四川成都)④:100701药物化学 B+ 等( 20 个) :延边大学(吉林延吉)、郑州大学、中南大学、华东理工大学(上海)、青岛科技大学、上海交通大学、广西医科大学、天津大学、中山大学(广州)、重庆医科大学、河北医科大学、吉林大学、首都医科大学、河北科技大学、内蒙古医学院、南开大学、厦门大学、烟台大学、贵州大学、天津科技大学 ⑤:100703生药学

2021年中山大学药剂学学硕专业考研必看成功上岸前辈复习经验分享

中南大学药学院药剂学考研成功经验分享 距离2020考研拟录取已经有一会儿了,一直想静下心来用文字记录一下自己这一年来的历程。最近终于把毕业相关的事情以及杂七杂八的琐事儿都弄完了就想着写一下自己在考研过程中的心得。本人考研中山大学药学院药剂学学硕初试:英语一77分、思想政治理论78分、专业课666药学综合A 213分,总成绩368分。 一、关于择校和定专业 我是在大四那个寒假才开始着手收集考研的目标院校资料,自己先敲定了考研的专业大方向,那就是药学专硕或者是学硕中的药剂学或者药理学,再结合自己喜欢的城市最终筛选出了: (1)北京协和医学院的药理学(学硕)专业课考试科目是652药学综合(在微生物学、分析化学、有机化学、生理学、生物化学中任选两门) (2)中山大学的药学专硕专业课考试科目是349药学综合以及药学学硕中的药剂学和药理学专业课考试科目是666药学综合A或667生物综合或668医学综合或669化学综合 (3)中南大学湘雅药学院的药学专硕考349药学综合(包括药事管理、药理学、药剂学)湘雅医院的临床药学学硕考781医学综合(包括生理、生化、病理、内科、外科)或741药基综合(包括基础、有机以及分析化学) (4)华中科技大学的药剂学或临床药学 (5)电子科技大学的药学专硕考349药学综合(包括药理、药剂、药分、药化) 综合考量下来,因为自己本科时四大药学得较好,其它科目学得一般,而且有自己相熟的本科直系学姐去年成功上岸中大药学专硕,想着找专业课的资料以及进行后期各种咨询会方便。再有就是沿海地区的药学发展相对较好,中大的药理毒理学,药剂与制药工程在全国都是顶尖学科。药学院有广州校区和深圳校区,深圳校区往年分数线相对要低一点,两个校区专业课考试参考书目一样就想着自己先复习着走。看十月份的状态再具体选择校区。中山大学的药学学硕每年竞争都比较激烈,除掉推免名额,一般药剂统招只有2-4个名额,药理有6-8个左右,专硕除掉推免名额一般招50-60个,今年因为国家政策招了80个左右。所以除非是本科特别优秀且有拿得出手的科研奖项不然就报专硕稳妥一点。 关于在择校和定专业中,自己一开始也是很小白,在搜集了大量的资料之后慢慢有了清晰的方向。在后期医院实习中了解到了临床药学在医院主要做治疗药物监测、不良反应的申报以及患者的用药教育,但是在国内该专业发展起步不久,

何立群教授情况简介 - 上海中医药大学

合作导师何立群 一、简介 何立群男 1959年8月生浙江 宁波人,医学博士。 1982年毕业于上海中医学院,2005 年在上海中医学大学获医学博士学位。 1995、2006年先后二次赴日本富山医科 药科大学和汉药研究所和美国Baylor 医药院从事研究工作。现任上海市中医 药研究院中医肾病研究所所长,上海中 医药大学附属曙光医院肾内科主任,上海中医药大学肾内科学科带头人;上海市高校中医内科学E-研究院特聘研究员。兼任国家自然科学基金同行评议专家、国家发展改革委员会药品价格评审专家、国家FDA药品评审专家、中华中医药学会肾病分会副主任委员兼秘书长,上海中医学会肾病专业委员会主任委员,上海市中西医结合学会肾病专业委员会副主任委员,上海市政府采购咨询专家,上海市卫生系列高级专业技术职务任职资格评审委员会委员兼学科组中医一组组长。《中国中西医结合肾病杂志》、《中国医刊》、《临床肾脏病杂志》、《上海中西医结合学报》等八家国内核心杂志的常务编委和编委。曾先后获上海市卫生系统“银蛇奖”;全国卫生系统优秀工作者;上海市劳动模范;上海市优秀学科带头人;上海市医学领军人才和上海市领军人才。 主要科研成果 长期从事中医药防治慢性肾脏疾病的临床和基础研究,在治疗慢性肾炎、肾病综合征、蛋白尿、血尿、早中期慢性肾功能衰竭、慢性尿路感染、肾盂肾炎肾小管间质病变等方面取得显著的成绩,根据自己的临床经验研制出治疗肾病综合症蛋白尿的经验方“四蚕汤”和治疗慢性肾衰的中成药制剂抗纤灵冲剂在治疗肾病综合征蛋白尿和改善肾功能及肾纤维化方面已取得明显的临床及实验疗效,分获中华中医药学会、中国中西医结合学会和上海市及上海市医学会科技进步奖二、三等奖共9项,近5年来在《JASN》、《Phytotherapy Research》等英、美、

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药学类二级学科排名 : 药剂学( 40) 排等排等排 学校名称学校名称学校名称等级名级名级名 1沈阳药科大学A+4复旦大学A7北京大学A 2中国药科大学A+5浙江大学A8中山大学A 3四川大学A6上海交通大学A B+等 (12个):华中科技大学、浙江中医药大学、哈尔滨医科大学、南方医科大学、中南大学、西安交通大学、贵阳医学院、广东药学院、上海中医药大学、天津大学、安徽中医学院、成 都中医药大学 B 等(12 个) :延边大学、河北医科大学、山东大学、青岛科技大学、河南大学、黑龙江中医药大学、江苏大学、江西中医学院、南京中医药大学、兰州大学、武汉理工大学、新疆医科大学 C等(8 个) :名单略 药物化学( 66) 等排等排 排名学校名称学校名称学校名称等级 级名级名 1中国药科大学A+6重庆大学A11复旦大学A 2北京大学A+7武汉大学A12广东药学院A 3沈阳药科大学A+8暨南大学A13浙江工业大学A 4中国海洋大学A9浙江大学A 5四川大学A10山东大学A

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