非法器官移植案例双语阅读-癌症细胞竟随器官移植传播
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第 1 页 共 7 页 非法器官移植案例双语阅读:癌症细胞竟随器官移植传播
An
extraordinary and terrifying medical case revealed in
the July issue of the?American Journal of
Transplantation?proves that organ transplants can pass
not only certain infectious diseases to recipients, but
in rare cases, also cancer.
《美国移植杂志》七月刊披露的一个离奇骇人的病例证实，器官移植不但会把某些传染性疾病传给器官接受者，在极少数情况下还会把癌症传给接受者。
Patients known to have malignant tumors are often not
able to donate their organs, but that was not the case of
a 53-year-old woman who died of a stroke in
20XX.She
had no known conditions that could prevent doctors
from transplanting her organs, and repeated tests
revealed no sign of cancer.The
woman’s kidneys, lungs, liver and heart were
transplanted into donor recipients, but instead of saving 第 2 页 共 7 页 their lives, they infected four of the five recipients
with cancer, while the fifth died of unrelated causes
shortly after the transplant.
已知患有恶性肿瘤的病人通常不能捐献自己的器官，但20XX年死于中风的一名53岁女性并不属于这种情况。她没有任何已知的病症阻止医生移植她的器官，而反复的检查也没有显示出癌症的迹象。这名女性的肾、肺、肝及心脏被移植给了几个器官接受者，结果非但没有救这些人的命，反而让五个接受者中的四人都染上了癌症，而第五个人在接受器官移植后不久就因其他原因去世。
The four organ recipients had recovered well after
the transplants, but
16 months later, the woman who had received the
donor’s lung fell ill and was subsequently diagnosed
with cancer in the lymph nodes in her chest.Unfortunately,
we live in an age when someone is diagnosed with
cancer every couple of minutes, but what made this case
remarkable was that tests showed the cancerous cells were
actually breast cancer cells.Further
DNA analysis revealed that they had e from the organ
donor. 第 3 页 共 7 页 四个器官接受者在接受移植后一开始都恢复得不错，但16个月之后，接受肺移植的女性就病倒了，随后被诊断出胸部的淋巴结有癌细胞。不幸的是，我们生活在一个每几分钟就有人被诊断出癌症的年代，但这个病例的离奇之处在于，测试结果显示，这些癌细胞实际上是乳腺癌细胞。进一步的DNA分析揭示，乳腺癌细胞来自器官捐赠者。
The lung recipient’s cancer spread and she died
about a year after her disease was discovered.At
the time, the remaining three organ recipients were
notified that the deceased had bee infected with cancer
from the organ she had received, and advised to get
themselves tested regularly just to make sure the same
thing doesn’t happen to them.Unfortunately,
that wasn’t enough…
接受肺移植女性的癌细胞扩散，并在发现癌症一年后去世。此时医院告知其余三位器官接受者，逝者的癌症来自她被移植的器官，并建议他们定期做检查，确保他们不会同样染上癌症。不幸的是，这样的防范还不够……
In
2021, four years after the transplant, the liver
recipient was diagnosed with breast cancer cells in her
liver.She 第 4 页 共 7 页 was given the option of undergoing another transplant,
but she refused for fear of potential plications.She
opted for radiation treatment, which proved
successful at first, but the cancer returned, and she
died in
20XX.
2021年，在接受器官移植四年后，接受肝移植的人被诊断出肝脏中有乳腺癌细胞。医生给她的选择是再一次接受肝移植，但她因担心出现潜在并发症拒绝了。她选择接受放射疗法，一开始还比较成功，但后来癌症复发，她于20XX年去世。
The person who had received the left kidney in
20XX, was diagnosed with cancer in
20XX, six years after the transplant.The
disease had already spread to several organs when it
was discovered, and the patient passed away two months
later.
20XX年接受左肾移植的人于20XX年，也就是移植6年后，被诊断出癌症。发现癌症时癌细胞已经扩散到几个器官，病人于两个月后离世。
The right kidney was transplanted into a 32-year-old
man.In 第 5 页 共 7 页 2021, tests revealed breast cancer cells in his
transplanted organ, but he underwent another surgery to
have the kidney removed, underwent chemotherapy and
stopped taking medicine that suppressed his immune
system.He
has been cancer free for
10 years.
右肾被移植到一个32岁的男子身上。2021年，检查结果显示，在他被移植的器官内发现了乳腺癌细胞，但他做了一个摘除肾脏的手术，接受了化疗，并停服抑制免疫系统的药物。如今距离他癌症痊愈已有十年。
"Many reports have shown that cancer transmission can
occur in solid organ transplantation,” the authors of
the recently published case note wrote.“However,
this is the first report describing breast cancer
transmission after a multi-organ procedure from one donor
to four recipients.”
最近这篇病例解析报告的作者写道：“许多报告显示，癌症传播可能在实体器官移植中发生。不过，这是首份描述一对四多器官移植中乳腺癌传播的病例报告。”
It’s worth pointing out that while terrifying, this
case is incredibly rare.Dr. 第 6 页 共 7 页 Lewis Teperman, director of organ transplantation at
Northwell Health in New Hyde Park, New York, writes that
passing cancer through organ donation is “very unmon”,
with chances varying between 0.01 and 0.05 percent.
值得指出的是，尽管很骇人，这种情况还是十分罕见的。位于纽约新海德公园的诺斯维尔保健集团器官移植中心主任路易斯·塔伯曼医生写道，通过器官移植传播癌症“很不寻常”，几率只有0.01%到0.05%之间。
It’s not clear exactly how the breast cancer
remained undetected during the screening performed before
the transplants, or how it was able to grow in each of
the four patients.Researchers
believe that the donor may have had “micro
metastases”, groups of cells too small to be detected by
imaging tests, and that immunosuppressant drugs played a
part in helping the cancer spread.Such drugs are taken by
organ recipients so that their bodies don’t reject the
