Type 2: cerebral amyloid angiopathy
progressive accumulation of congophilic, βA4 immunoreactive, amyloid protein in the walls of small-to-mediumsized arteries and arterioles predominantly located in the leptomeningeal space, the cortex, and, to a lesser extent, also in the capillaries and veins. In the most severe form of cerebral amyloid angiopathy, the vessels become dilated and disrupted, with focal wall fragmentation and blood extravasation, with or without microaneurysmal dilatation, and sometimes show luminal occlusion.
FLAIR=fluid-attenuated inversion recovery液体抑制反转恢复序列 Lancet Neurol 2010; 9: 689–701
与SVD紧密相关的几个概念
澄清概念
Silent stroke:三种译法 尚有争议:静止性卒中、 无症状性卒中、亚临床卒 中 小血管病 轻卒中 轻卒中 silent stroke
腔隙性梗死 (Lacunar infarction)
silent stroke 有时用silent infarct,是指 无明确的卒中病史,无明 确的神经系统定位体征, 由影像学检查或尸检发现 的脑梗死或卒中