ACYW135

Data SheetKey SpecificationsKey Features•2x2 MU-MIMO with two spatialstreams per radio•Third 2x2 MIMO radio for dedicated RFand WIPS scanning•802.11ac Wave 2 support •Up to 400 Mbps for 2.4 GHz radio •Up to 867 Mbps for 5 GHz radio •Integrated omnidirectional antennas •20/40/80 MHz channel width support •Integrated BLE •2x Gigabit Ethernet port•Full Operational Capacity with 802.3atPoE+•Distributed Data Plane architecture •Zero-touch deployment through automatic cloud activation and configuration •Cloud or on premises management plane options •Operating modes for dedicated access, dedicated security or dual-mode •Support for up to 8 distinct SSIDs per radio •Integrated firewall, traffic shaping, QoS and BYOD controls per SSID •Dynamic RF optimization through smart steering, band steering and optimal channel selection •Application visibility through layer 7 deep packet inspection •Automated device access logging •Patented Marker Packettm technology for rogue AP detection and classification •Wired VLAN monitoring for “No-WiFi” zone enforcement •Third party analytics integration with real-time data transfer •Self-healing wireless mesh networkingTop Performance at the Best PriceArista W-118 is an enterprise-grade 2x2 MU-MIMO tri-radio 802.11ac wall plate access point with dual concurrent 5 GHz and 2.4 GHz radios supporting 802.11a/n/ ac Wave 2, 802.11b/g/n, two spatial streams, and data rates of up to 876 Mbps and 300 Mbps, respectively. It also contains a third 2x2 MIMO 802.11ac radio for dedicated multi-function scanning and a fourth 2.4 GHz Bluetooth Low Energy (BLE) radio.Why Choose the W-118?The W-118 provides best value amongst high-performing, modern wall plate access points designed for cost conscious organizations. Built using the latest 802.11ac Wave 2 chipsets, the W-118 is perfect for medium density environments looking for the high performance and advanced features of current accesspoints without the high cost. Common deployment scenarios include small and medium schools, distributed remote offices, small meeting rooms, and enterprise campuses.The W-118 provides access to advanced access point features like role-based firewalls and application visibility without the high cost typically associated with Wave 2 devices. The W-118 is also a perfect fit for organizations in need of future-ready dedicated security sensorsiBeacon Bluetooth Low Energy SupportThe Arista W-118 supports the iBeacon Bluetooth Low Energy (BLE) standard. BLE is used for proximity based services on mobile devices via an application ecosystem. W-118 can be configured to advertise a unique identifier through iBeacons at a periodic interval.Arista Cloud Managed WiFiThe W-118 is managed by the Arista cloud and leverages a purpose-built cloud architecture to produce enterprise-grade wireless networks for every application required, ensuring high reliability through an approach that is automated, scalable, secure and cost effective.What Really MattersThe future of WiFi requires intelligent, self-reliant access points that support high-performing, highly reliable networks without the need for antiquated controllers. This approach removes the complexity, instability and high costs associated with enterprise WiFi today.Arista W-118AccessThe W-118 creates WiFi networks that require less time and resources to deploy and maintain compared to traditional devices, resulting in significant cost savings.• Plug and play provisioning using either Cloud or On-premise deployments - Arista Access Points take less than two minutes to activate and configure after connecting to the cloud• Support for up to eight individual SSIDs per radio providing maximum flexibility in network design• Network controls like NAT, Firewall and QoS implemented at the Access Point, ensuring faster and more reliable networks• Continuous scanning of all 2.4 GHz and 5 GHz channels by a dedicated 2x2 third radio provides a dynamic, 360 degree view of the RF environment to assist in RF optimization and client handling• Network availability and performance assurance using the third radio as a client to conduct on-demand and scheduled connectivity and performance tests• Smart steering addresses sticky client issues by automatically pushing clients with low data rates to a better access point• Band steering manages channel occupancy, pushing clients to the 5 GHz channel for optimal throughput• Smart load balancing distributes load evenly across neighbouring APs to optimize the use of network resources• Arista Wi-Fi’s distributed data plane architecture continues to serve users and secure the network even if connection with the management plane is interrupted• Interference avoidance from LTE/3G small/macro cells in commonly used TDD/FDD frequency bandsSecurityThe W-118 offers complete visibility and control of the wireless airspace that keeps the integrity of the network in check and actively protects users without manual intervention.•W-118 is equipped with industry leading fully integrated wireless intrusion prevention capabilities•Multifunction third radio provides uninterrupted spectrum scanning or client emulation for always on security coverage alongside dedicated 2.4G/5G client radios.•Arista’s patented Marker PacketsTM help accurately detect rogue access points on any network while minimizing false positives •Third radio used as a dedicated security sensor for 24x7x365 scanning and automated over-the-air (OTA) prevention •Deterministic rogue AP detection and prevention by monitoring all WiFi and non-WiFi VLANs.•Over-the-air and on-the-wire prevention techniques assure automatic and reliable threat prevention to keep unauthorized clientsand rogue APs off the network without impacting authorized connections.•Access Points autonomously scan for wireless threats and enforce security policy even if disconnected from the cloud management plane•VLAN monitoring enables a virtual connection to non-WiFi networks for complete network rogue detection and prevention AnalyticsThe W-118 collects massive amounts of data and supports immersive guest network experiences that develop and reinforce the relationship between them and the brand.• Reports of customer footfall, demographic, loyalty and other analytics provide insightful and actionable information.• Supports proximity marketing programs that trigger when certain devices are present, which includes automatic messaging vis MMSin-browser notifications and real time notifications sent to 3rd party systems that alert to the presence of enrolled devices.Property SpecificationPhysical Dimensions186.4mm X 123.9mm X 25.5mm / 7.3” X 4.9” X 1”Weight .455kg (1 lb)Operating Temperature 0o C – 40o C (32o F – 104o F)Storage Temperature -25o C – 75o C (-13o F – 167o F)MTBF535,205 hr @ 40o C1,081,559 hr @ 25o CHumidity0%-95% non-condensingP ower consuption11.8W (max) / 5.1W (min) / 8.3W (avg)Chipset Qualcomm QCA4019 SOCProcessor RAMQualcomm IPQ4019 717MHz quad core ARMprocessor with 512 MB RAM and 32 MB Flash Physical SpecificationsPort Description Connector Type Speed/ProtocolPower12V 2A5.5mm overalldiameter/2.1mmcenter pin/holePass-throughportThe pass-through port is used to pluga device into another wired port thatis available on the wall where the AP isinstalled. The pass-through port at therear of the device and pass-throughport on the bottom of the device areinternally connected.RJ-45--Ethernet(LAN3/PSE)Gigabit Ethernet port that can be usedfor wired extension for an SSID. Thisport also provides the power for thedevice using the 802.3af standardRJ-4510/100/1000 MbpsGigabit EthernetEthernet(LAN2/LAN1)Gigabit Ethernet port that can be usedfor wired extension for an SSID.RJ-4510/100/1000 MbpsGigabit EthernetReset Reset to factory default settingsPin hole pushbuttonHold down andpower cycle thedevice to resetOperational Specifications Port DescriptionConnectorTypeSpeed/Pro-tocol PassthroughThis is a wired port that facilitatesextension of the wired network after theAP is mounted on the wall. Another devicecan be plugged in to the pass-through porton the bottom of the W-118 device. Thetraffic on the pass-through port does notinterfere with the AP traffic. No policies canbe applied on the pass-through port traffic.RJ-45-WANEnables the connection to wired LANthrough a switch or hub. The device canthen communicate with the server. Thisport also provides the power for the deviceusing the 802.3af standardRJ-4510/100/1000Mbps EthernetPower overEthernetInput Power12V DC 2ANumber of Radios 3 WiFi Radios: One 2.4 GHz and 5 GHz radio each for simultaneous dual band client access. Athird dual-band radio dedicated to non-access smart scanning; WIPS, RF optimization, Remote Troubleshooting, and network assurance functions.1 BLE Radio: A fourth Bluetooth Low Energy radio for proximity based services on mobile devices via an application ecosystem.Max Clients Supported512 clients per radio (dependent upon use cases)MIMO2x2 for 2.4/5GHz RadiosNumber of Spatial Streams 2 for 2.4/5GHz RadiosRF Transmit Power20 dBm per radio chain (max); Actual power for Tx will depend on Country Regulatory Domain Simultaneous MU-MIMO Clients Two 1x1 MU-MIMO clientsUsers in a MU-MIMO group with a2x2 client1Bandwidth Agility YesFrequency Bands 2.4-2.4835 GHz, 4.9-5.0 GHz, 5.15-5.25 GHz (UNII-1), 5.25-5.35 GHz, 5.47-5.6 GHz,5.650-5.725 GHz (UNII-2), 5.725-5.85 GHz (UNII-3)Dynamic Frequency Selection Supported in compliance to all latest amendments from FCC, CE, IC, CB, TELEC, KCC regarding certifications.Frequency, Modulation and Data RatesIEEE 802.11b/g/nFrequency BandScanning TransmissionAll regionsUSA & Canada(FCC/IC)Europe(ETSI) 2400 ~ 2483.5 MHz2400 ~ 2473.5 MHz2400 ~ 2483.5 MHzModulation Type DSSS, OFDMPeak Data Rates Up to 300 Mbps (MCS 0-15)Antenna Integrated modular high efficiency PIFA antenna x4 (peak gain 5.0 dBi)IEEE 802.11a/n/acFrequency Band Scanning TransmissionAll regions USA & Canada(FCC/IC)Europe(ETSI)4.92 ~5.08 GHz5.15 ~ 5.25 GHz 5.25 ~ 5.35 GHz 5.47 ~ 5.725 GHz 5.725 ~ 5.825 GHz 5.15 ~ 5.25 GHz5.25 ~ 5.35 GHz5.725 ~ 5.825 GHz5.15 ~ 5.25 GHz5.25 ~ 5.35 GHz5.47 ~ 5.725 GHzDynamic Frequency Selection DFS and DFS2Modulation Type OFDMPeak Data Rates Up to 867 Mbps (MCS 0-15)Antenna Integrated modular high efficiency PIFA antenna x4 (peak gain 5.0 dBi)Maximum Aggregate Transmit PowerFor 2.4 GHzMCS Index Transmit Power(dBm)802.11b1 Mbps -11 Mbps22802.11g6 Mbps - 48 Mbps2554 Mbps802.11n HT20MCS 0,1,2,3,4,524802.11n HT40MCS 0,1,2,3,4,5 24For 5 GHzMCS Index Transmit Power(dBm)802.11a6 Mbps - 48 Mbps26.802.11n HT20MCS 0,1,2,3,4,526802.11n HT40MCS 0,1,2,3,4,526802.11ac VHT80MCS 0,1,2,3,4,5,6,726Note:The actual transmit power will be the lowest of:• Value specified in the Device Template• Maximum value allowed in the regulatory domain • Maximum power supported by the radioData Sheet Receive SensitivityFor 2.4 GHzMCS Index Receive Sensitivity (dBm)802.11g6 Mbps -9224 Mbps -36 Mbps -48 Mbps -54 Mbps -75802.11n HT20MCS 0, 8 -92MCS 1,9MCS 2,10MCS 3,11MCS 4.12MCS 5,13MCS 6,14MCS 7, 15 -73802.11n HT40MCS 0, 8 -89MCS 1,9MCS 2,10MCS 3,11MCS 4,12MCS 5,13MCS 6,14MCS 7, 15 -71.5 For 5 GHzMCS Index Receive Sensitivity (dBm)802.11a6 Mbps -9024 Mbps36 Mbps48 Mbps54 Mbps -74.5802.11n HT20MCS 0, 8 -90MCS 1,9MCS 2,10MCS 3,11MCS 4,12MCS 5,13MCS 6,14MCS 7,15 -73802.11n HT40MCS 0, 8 -88.5MCS 1,9MCS 2,10MCS 3,11MCS 4,12MCS 5,13MCS 6,14MCS 7, 15 -70For 5 GHzMCS Index Receive Sensitivity (dBm)802.11n VHT20MCS 0 -90MCS 1MCS 2MCS 3MCS 4MCS 5MCS 6MCS 7MCS 8 -69802.11n VHT40MCS 9-65802.11n VHT80MCS 0 -85.5MCS 1MCS 2MCS 3MCS 4MCS 5MCS 6MCS 7MCS 8MCS 9 -61Data Sheet5 GHz2.4 GHzInternal Antenna Radiation Patterns Internal Antenna Radiation Patterns dBi gaindBi gainData SheetHeadquarters5453 Great America Parkway Santa Clara, California 95054408-547-5500Copyright 2020 Arista Networks, Inc. The information contained herein is subject to change without notice. Arista, the Arista logo and EOS are trademarks of Arista Networks. Other product or service names may be trademarks or service marks of others.Support******************408-547-5502866-476-0000Sales****************408-547-5501866-497-0000Ordering Information : Access Point Power Part Number DescriptionAP-W118-SS-5Y W-118 2x2:2 tri radio 802.11ac Wave-2 wall plate access point with internal antennas and 5 year Cognitive Cloud SW SubscriptionAP-W118-SS-3Y W-118 2x2:2 tri radio 802.11ac Wave-2 wall plate access point with internal antennas and 3 year Cognitive Cloud SW SubscriptionAP-W118W-118 2x2:2 tri radio 802.11ac Wave-2 wall plate access point with internal antennas Part Number DescriptionPWR-AP-W4Universal AC power supply for all APs except for C-110PWR-AP-PLUS-NA One port 802.3at PoE+ injector for use with all Access Point models. Includes USA power cord. Not for outdoor use.”PWR-AP-W2Universal AC power supply for C-120, C-130, W-118 and C-100October 1, 2020Regulatory Specifications RF and ElectromagneticCountry CertificationUSA FCC Part 15.247, 15.407EuropeCE EN300.328, EN301.893Countries covered under Europe certification: Austria, Belgium, Cyprus, Denmark, Estonia, Finland, France,Germany, Greece, Hungary, Ireland, Italy, Iceland, Luxembourg, Latvia, Lithuania, Malta, Netherlands, Norway,Poland, Portugal, Spain, Sweden, Slovakia, Slovenia, Switzerland, The Czech Republic, UK.CountryCertificationUSA UL 60950CanadacUL 60950European Union (EU)EN 60950, RoHSSafety*For complete country certification records, please visit the site: https:///en/support/product-certificate AP-W118-R WW-118-R W 2x2:2 tri radio 802.11ac Wave-2 wall plate access point with internal antennas (bundled with Stand, Power supply, Ethernet cable)PWR-AP-W3Non-discountable purchase. Universal AC power supply for W-118, C-120, C-130 and C-100, 12VDC, 2A, Center +, DC Plug 5.5mm*2.1mm*L9.5mm, US UK Euro AU Plugs。

附件22 2019版XX省非免疫规划疫苗接种知情同意书
ACYW135群脑膜炎球菌多糖疫苗
受种者姓名：性别：出生日期：年月日根据《中华人民共和国疫苗管理法》第九十七条：非免疫规划疫苗，是指由居民自愿接种的其他疫苗。

ACYW135群脑膜炎球菌多糖疫苗为非免疫规划疫苗。

【疾病简介】流行性脑脊髓膜炎是由脑膜炎奈瑟菌引起的急性呼吸道传染病，起病急、病情重，有发热、头痛、呕吐、皮肤出血点及脑膜刺激征，严重者可有败血症休克和脑实质损害，危及生命。

引起流行性脑脊髓膜炎的脑膜炎奈瑟球菌有12个血清群。

【疫苗作用】预防A、C、Y、W135群流行性脑脊髓膜炎。

【接种禁忌】
1.对该疫苗所含任何成分过敏者。

2.患急性疾病、严重慢性疾病、慢性疾病的急性发作期和发热者。

3.患脑部疾病、癫痫及有过敏史。

4.肾脏病、心脏病、活动性结核患者。

【不良反应】
1.常见不良反应：接种部位1-2天的红肿、硬结、疼痛，发热。

2.罕见不良反应：过敏反应等。

如接种疫苗后诊断为异常反应，已购买基础保险的由保险公司补偿，未购买基础保险的由疫苗企业补偿。

【注意事项】
1.家族和个人有惊厥史者、患慢性疾病者、有癲痫史者、过敏体质者、孕妇、哺乳期妇女慎用。

2.接种后请留在接种门诊观察30分钟，无异常后方可离开。

请您认真阅读以上内容，如实提供受种者的健康状况和是否有接种禁忌等情况。

如有疑问请咨询医疗卫生人员。

因疫苗特性或受种者个体差异等因素，疫苗保护率并非100%。

本疫苗自愿自费接种。

ACYW135群脑膜炎球菌多糖疫苗ACYW135 Qun Naomoyanqiujun Duotang YimiaoGroup ACYW135 Meningococcal Polysaccharide Vaccine 本品系分别用A群、C群、Y群、W135群脑膜炎球菌培养液，分别提取和纯化A群、C群、Y群、W135群脑膜炎球菌多糖抗原，混合后加入适宜稳定剂后冻干制成。

用于预防A群、C群、Y群、W135群脑膜炎球菌引起的流行性脑脊髓膜炎。

1 基本要求生产和检定用设施、原料及辅料、水、器具、动物等应符合“凡例”的有关要求。

2 制造生产用菌种为A群脑膜炎球菌CMCC 29201（A4）菌株、C群脑膜炎球菌CMCC 29205（C11）菌株、Y群脑膜炎球菌CMCC 29028、W135群脑膜炎球菌CMCC 29037或其他经批准的菌种。

2.1混合前单价原液2.1.1A群、C群、Y群、W135群脑膜炎球菌多糖原液应分别符合“A群脑膜炎球菌多糖疫苗”中2.1～2.2项的规定。

原液制备过程中可采用经批准的方法去除内毒素。

2.1.2 原液检定按3.1项进行。

2.1.3 保存及有效期粗制多糖、精制多糖原液或原粉于－20℃以下保存。

自收获杀菌之日起至成品疫苗，总有效期应不超过60个月。

2.2 半成品2.2.1 配制用无菌、无热原乳糖溶液和灭菌注射用水稀释原液即为半成品。

每1次人用剂量含A群多糖50μg，C群多糖50μg，Y群多糖50μg，W135群多糖50μg，乳糖2.5～10mg。

2.2.2 半成品检定按3.2项进行。

2.3 成品2.3.1 分批应符合“生物制品分批规程”规定。

2.3.2 分装及冻干应符合“生物制品分装和冻干规程”规定。

冻干过程中制品温度不高于30℃，真空或充氮封口。

2.3.3 规格按标示量复溶后每瓶0.5ml。

每1次人用剂量0.5ml，含A群、C群、Y群、W135群多糖各50μg。

2.3.4 包装符合“生物制品包装规程”规定。

ACYW135群四价流脑多糖疫苗接种告知书
流行性脑脊髓膜炎（简称流脑）是由脑膜炎双球菌引起的化脓性脑膜炎，传染性较强，主要在冬春季流行，空气飞沫传播，主要侵犯对象为儿童及青壮年，15岁以下儿童发病占75%。

脑膜炎双球菌分13个血清群，常见的有A、B、C 群。

江苏省近年已出现W135群病例。

接种流脑疫苗是预防流脑的有效手段。

根据《中华人民共和国传染病防治法》和《疫苗流通和预防接种管理条例》，流脑A+C群流脑多糖疫苗为第一类疫苗，如无禁忌，公民应当接种。

ACYW135群四价脑膜炎球菌多糖疫苗可替代免疫规划程序中的A+C群流脑多糖疫苗，并增加了Y和W135群流脑的成分。

ACYW135群四价流脑多糖疫苗属第二类疫苗，公
1. 接种后应在接种单位留观区域留观30分钟。

2. 到目前为止，任何疫苗的保护效果都不能达到100%。

少数人接种后未产生保护力，或仍然发病，与疫苗本身特性和受种者个人体质有关。

3. 如需了解更多信息，请查看产品说明书。

若本告知书的内容与产品说明书发生冲突的，以产品说明书为准。

【接种前受种者应告知/医生应询问下列健康状况】
1. 是否发热或其他不适症状？
2. 是否以往接种本疫苗后有不适？
3. 是否处于疾病的急性发作期？
4. 是否近期接受过输血或使用过免疫球蛋白？。

Description of Included ModelsSafety ListingsAvailable OptionsSeries 600 AC Powered PumpsModel FR610C Pump ShownModel NumberDescriptionShipping Weight FR610C Heavy Duty AC Utility Pump with 3/4" X 12' Hose & Nozzle, Telescoping Suction Pipe and 1/4 HP - 115 VAC/60 HZ Motor.31 lbs FR611C Heavy Duty AC Utility Pumpwith 3/4" X 12' Hose & Nozzle, TelescopingSuction Pipe, 1/4 HP - 115 VAC/60 HZ Motor, and Model 807C1 Meter Installed.39lbsApproval MarkOrganization DescriptionFileNumber Guide NumberUnderwriters Laboratories Inc ., a nationally recognizedindependent organization for testing of products to ensure public safety. Recognized and accepted in USA,Canada and other countriesMH7817 RCRXOption DescriptionChange In ShippingWeight (lbs.)Change In ShippingWeight (kgs.)A Upgrade to automatic nozzle from standard manual nozzle.2.0 0.9 Unit equipped with meter registering liters inAccessoriesPerformance1 Nominal flow rate at nominal voltage using a standard hose and manual nozzle with low viscosity fluid.* Consult factory for extreme temperature applications outside this range.** The lift in feet is equivalent to the vertical distance from the surface of the fluid in the tank to the inlet of the pump, PLUS the friction losses through the vertical and horizontal runs of pipe, all elbows and other fittings. The system should be designed to require a minimum amount of suction lift.Part Number Description4200F9111 Nozzle Spout Hook (for automatic nozzles)FRH07512Buna-N hose 3/4" X 12' with static wire, 3/4" ferrules and spring gaurds1200KTG9099 Telescoping steel suction pipe - 1"NPT threads - Extends 22" to 40"NO75UMN11 Manual unleaded nozzle with 3/4" inlet NO75UAU11 Automatic unleaded nozzle with 3/4" inlet 400F6634Wall mount bracket for this pump1200KTF7019 Hydrosorb Filter Kit - 1200KTG9075 cast iron 3/4" adapter with F180PM0 filter for ModelFR76101200KTF7018Particulate Filter Kit - 700ACCF7017 cast iron 1" adapter with 700ACCF7014 filter for Model FR4210F180PC1 Clear Bowl, 10 micron prticulate filter w/ drain valveF1810PM1 Metal canister 10 Micron particulate filter w/ drain valve. Fits 1200KTG9075 filter headMaximum outlet pressure 12 PSI (0.83 BAR)Maximum flow rate (1)15 GPM (53 LPM)Maximum Recommended Viscosity of Pumped Fluid Diesel Fuel Maximum ambient operating temperature 150 °F (66 °C)*Minimum ambient operating temperature -15 °F (-26 °C)*Minimum Dry Vacuum 6 Inches of Hg.Minimum Suction Lift**7 feet for gasoline*** & 8 feet for Diesel fuel.Flow CurveFluid CompatibilityThe FR600 Series pumps are compatible with the following fluids: Diesel, Gasoline, Kerosene, Mineral Spirits, Heptane and Hexane.The FR600 Series pumps are NOT compatible with the following fluids: Acetone, Ammonia, Benzene Bleach, Hydrochloric Acid, Water, Ink, Toluene, Aviation Gas and Jet Fuel..If in doubt about the compatibility of a specific fluid, contact the supplier of the fluid to check for any adverse reactions to the following wetted materials.A. FR600 with 3/4" X 12' hose and manual nozzle.B. FR600 with 3/4"X 12' hose, manual nozzle and 800 meter.C. FR600 with 3/4" X 12' hose, manual nozzle, 800 meter and 10 micron filterD. FR600 with 3/4" X 12' hose and OPW 11-A automaic nozzle.E. FR600 with 3/4" X 12' hose, OPW 11-A automaic nozzle and 800 meter.F. FR600 with 3/4" X 12' hose, OPW 11-A automaic nozzle, 800 meter and10 micron filter.Nominal flow curve for Based on 3 feet suction lift. Actual flowrates obtained may vary.Cast Iron Steel Stainless Steel Bronze/Iron Carbon Polyester Aluminum Cork/Buna N Buna N Ceramic FiberZinc Plated Steel AcetalFluorocarbon TeflonRyton (FR611 Only)DimensionsRepairRefer to Owner's Operation & Safety Manual shipped with the pump and available for reference andprinting in the eLibraryTo maintain UL listing, motors that need repair should be taken to an authorized repair shop. Pumps must be thoroughly flushed and drained before being taken in for service.MaintenanceTo keep the pump running at its best, periodically perform the following procedures:1.Check strainer for dirt accumulation. To clean strainer, remove inlet flange and pull out screen.2.Remove rotor cover and inspect vanes. Vanes should be replaced after excessive wear to preventdamage to pump. If more than 1/2 the total blade length extends out of the rotor slot at the extreme of travel, the wear is excessive.3.Check hose and nozzle for wear or damage. Bad hoses or nozzles are potential safety hazards.For FR611 see meter's Owner's Operation & Safety Manual for additional recommendedmaintenance procedures.Frequently Asked Questions1. My pump only pumps for a few minutes and then stops. What is happening?Generally "short cycling" indicates the motor is drawing too much current from the power source for some reason, and the thermal relay is opening to protect the insulation from the resulting heat build up. If this is what is happening, the thermal relay will reset after 10 to 20 minutes and the motor will again operate. The causes of high current are many. The pump is designed for low viscosity fluid, like diesel or gasoline, and will overheat if used to pump oil or other higher viscosity fluids. The inlet filter screen could be clogged.Bearings could be defective resulting in a drag on the motor shaft.See the Troubleshooting Guide in your Owner's Manual shipped with your unit or the copy available in the eLibrary.2. There is fluid leaking out of the small hole in the side of the pump body. How do I stop it?This small hole is described as the "weep hole" and is positioned to drain fluid that has leaked past the dynamic seal between the pump and the motor. It is important that the leak be corrected as soon aspossible to avoid damage to the motor. A new shaft seal will need to be installed.See the Troubleshooting Guide in your Owner's Manual shipped with your unit or the copy available in the eLibrary.3. What can I do to avoid my pump from losing prime when it sits for a time?Maintaining "prime" or keeping fluid in the inlet piping of your pumping system requires that no air leak into that piping. Do not open the nozzle while pump is off. If your pump is consistently losing prime, check all joints and fittings paying particular attention to the suction tube to pump connection, and the variouscovers and caps in the pump itself. Teflon® type sealing tape or a sealing compound noted as resistant to fuels is recommended at all threaded pipe connections.4. When it gets hot outside my pump will not pump gasoline but my diesel pump works great,whais going on?A suction pump works by developing a vacuum above the fluid being pumped and depending onatmospheric pressure to force the fluid into that vacuum. The higher the fluid is being raised, the more vacuum is required. If the fluid turns to a gas at a lower vacuum than that required to raise the fluid out of the container, the system is said to be vapor locked. In other words, rather than enough vacuum being developed by the pump to raise the fluid, the pump is instead vaporizing the gasoline and only gas vapor i being pumped. Diesel has a very low vapor pressure at even relatively high temperatures so there is no danger of vapor locking at practical temperatures. Gasoline is blended to have different vapor pressures to aid in winter starting (high vapor pressure) or avoid vapor locking in the summer (lower vapor pressure).The unit of measure used in the industry for this characteristic is Reid Vapor Pressure. Having winter gas (high Reid Vapor Pressure), still available in your tank in a warm spring, is a common cause of vaporlocking pumps.Once the situation exists, there are a limited number of options. Decrease the "lift" needed to raise the gasoline by filling the tank to the top is the easiest and quickest. This has the added benefit of mixing in a new blend of gasoline with a lower vapor pressure which will average the blended Reid Vapor Pressure down. Another option is to decrease the temperature by shading and/or cooling the piping and pump in some fashion. In an emergency spraying water on the piping could drop the system temperaturesufficiently to allow gasoline to be pumped. Use extreme caution when spraying water around。

258生物技术世界 BIOTECHWORLD脑膜炎球菌根据表面荚膜多糖的差异又可以分为不少于13个血清群体,其中A、C、Y、W135这四种群Men是引发脑膜炎的主要致病菌,目前已经有针对这四种主要致病菌的多种单价或是多价疫苗[1]。

现在针对A、C、W135、Y群脑膜炎球菌的疫苗多是四价多糖,基本过程是细菌培养后纯化提取表面的荚膜多糖,然后验证多糖含量。

其中细菌培养和多糖纯化是制备疫苗的关键步骤,而目前测定多糖含量最简单也比较有效的方法是免疫火箭法。

1 疫苗生产根据成分不同,目前国内外有几种不同的培养细菌的液体培养基,李文春[2]等人在此基础上摸索出了一种成分比较简单、制作起来比较方便的比较适合细菌生长的综合的液体培养基,同时也提高了其荚膜的多糖产量。

经实验验证,该方法可以替代传统的半综合培养基,其成分明确,为疫苗的安全性提供了更加可靠的保证。

杨建勇[2]等人则发现在半综合培养基中补加1%的葡萄糖培养效果良好,此外菌种接种浓度也直接影响到多糖复合物的产量;最适ph值保持在6.5-7.5的范围可以维持W135群链球菌快速的生长;而温度控制在36.5±0.2℃可以得到较高的培养产物;在培养过程中加大通气量以及搅拌速度进一步也有利于菌群生长。

在确定如上最适培养条件后连续进行3批次500L罐放大培养,能够达到规模化生产要求。

多糖纯化方面,黄镇[3]等人提取多糖纯化后,采用超速离心结合层析技术去除多糖中的内毒素,并按照适当的比例配备成四价的多糖溶液,再加入保护剂制成冻干疫苗,这样生产的多糖疫苗内毒素含量少于10EU/ug,安全性大大提高,各项指标也均达标。

2 疫苗研发进展(1)多糖疫苗。

多糖疫苗是最先被研发的疫苗,截止到目前为止,全球已有针对对A、C、W135、Y群脑膜炎球菌的多种多糖疫苗病毒上市,也有较好的治疗效果。

但是因为多糖疫苗大部分属于T细胞非依赖型的抗原,婴幼儿免疫系统尚未发育完全,所以该疫苗在儿童中效价较低。

ACYW135群脑膜炎球菌多糖疫苗ACYW135 Qun Naomoyanqiujun Duotang YimiaoGroup ACYW135 Meningococcal Polysaccharide Vaccine 本品系分别用A群、C群、Y群、W135群脑膜炎球菌培养液，分别提取和纯化A群、C群、Y群、W135群脑膜炎球菌多糖抗原，混合后加入适宜稳定剂后冻干制成。

用于预防A群、C群、Y群、W135群脑膜炎球菌引起的流行性脑脊髓膜炎。

1 基本要求生产和检定用设施、原料及辅料、水、器具、动物等应符合“凡例”的有关要求。

2 制造生产用菌种为A群脑膜炎球菌CMCC 29201（A4）菌株、C群脑膜炎球菌CMCC 29205（C11）菌株、Y群脑膜炎球菌CMCC 29028、W135群脑膜炎球菌CMCC 29037或其他经批准的菌种。

2.1混合前单价原液2.1.1A群、C群、Y群、W135群脑膜炎球菌多糖原液应分别符合“A群脑膜炎球菌多糖疫苗”中2.1～2.2项的规定。

原液制备过程中可采用经批准的方法去除内毒素。

2.1.2 原液检定按3.1项进行。

2.1.3 保存及有效期粗制多糖、精制多糖原液或原粉于－20℃以下保存。

自收获杀菌之日起至成品疫苗，总有效期应不超过60个月。

2.2 半成品2.2.1 配制用无菌、无热原乳糖溶液和灭菌注射用水稀释原液即为半成品。

每1次人用剂量含A群多糖50μg，C群多糖50μg，Y群多糖50μg，W135群多糖50μg，乳糖2.5～10mg。

2.2.2 半成品检定按3.2项进行。

2.3 成品2.3.1 分批应符合“生物制品分批规程”规定。

2.3.2 分装及冻干应符合“生物制品分装和冻干规程”规定。

冻干过程中制品温度不高于30℃，真空或充氮封口。

2.3.3 规格按标示量复溶后每瓶0.5ml。

每1次人用剂量0.5ml，含A群、C群、Y群、W135群多糖各50μg。

2.3.4 包装符合“生物制品包装规程”规定。