・784•中华实验眼科杂志2019年10月第37卷第10期Chin J Exp Ophthalmol,October2019,Vol.37,No.10issn.1672-5123.2011.08.025.[7]张蹌，路强，崔巍•脯氨酸径化酶2在糖尿病视网膜病变中的研究进展[J].内蒙古医学杂志,2018,50(3):286-288.D01：10.16096/ ki.nmgyxzz.2018.50.03.012.Zhang H,Lu Q,Cui W.Progress of proline hydroxylase2in diabetic retinopathy[J].Inner Mongolia Med J,2018,50(3):286-288.DOI:10.16096/ki.nmgyxzz.2018.50.03.012.[8]Chen MC,Lee CF,Huang WH,et al.Magnolol suppresses hypoxia-induced angiogenesis via inhibition of HIF-1a/VEGF signaling pathway in human bladder cancer cells[J].Biochem Pharmacol,2013,85(9): 1278-1287.DOI：10.1016/j.bcp.2013.02.009.[9]Marxsen JH,Stengel P,Doege K,et al.Hypoxia-inducible factor・1(HIF-1)promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases.[J].Bio J,2004,381(3)：761-767.DOI：10.1042/ BJ20040620.[10]马昱，唐少华，姜燕荣，等.外源性脯氨酸疑化酶对人RPE细胞中缺氧诱导因子通路的负向调节作用[J]・中华实验眼科杂志,2016, 34(3):234-238.D01：10.3760/cma.j.issn.2095-0160.2016.03.009.Ma Y,Tang SH,Jang YR,et al.Negative regulation of exogeneous polyl・4-hydroxylase domain proteins on hypoxia-inducible factor pathway in human RPE cells[J].Chin J Exp Ophthalmol,2016,34(3): 234-238.DOI：10.3760/cma.j.issn.2095-0160.2016.03.009. [11]Takei A,EkstrOm M,Mammadzada P,et al.Gene transfer of prolylhydroxylase domain2inhibits hypoxia-inducible angiogenesis in a model of choroidal neovascularization[J/OL].Sci Rep,2017,7:42546 [2017-12-23].https：//www.nature,com/articles/srep42546.DOI:10.1038/srep42546.[12]杨宁，路强，袁梦克，等•黄苓素对缺氧诱导的视网膜神经胶质细胞中脯氨酸規化酶2表达的抑制作用[J].中华实验眼科杂志,2017, 35(11):990-996.DOI：10.3760/cma.j.issn.2095-0160.2017.11.007.Yang N,Lu Q,Yuan MK,et al.The inhibitory effects of baicalein on overexpression of proline hydroxylase2in hypoxia-induced retinal glial cells[J].Chin J Exp Ophthalmol,2017,35(11)：990-996.DOI：10.3760/cma.j.issn.2095-0160.2017.11.007.[13]Chiu CJ,Taylor A.Dietary hyperglycemia, glycemic index and metabolicretinal diseases]J].Prog Retin Eye Res,2011,30(1):18-53.DOI：10.1016/j.preteyeres.2010.09.001.[14]陈忠平，姜德咏，唐罗生，等•川茸嗪对糖基化终末产物诱导人视网膜色素上皮细胞表达低氧诱导因子・la的影响[J].中华眼底病杂志,2006,22(1):55-56.[15]Mazzone M,Dettori D,de Oliveira RL,et al.Heterozygous deficiency ofPHD2restores tumor oxygenation and inhibits metastasis via endothelial normalization]J].Cell,2009,136(5):839-851.DOI：10.1016/j.cell.2009.01.02.[16]Takeda K,Fong GH.Prolyl hydroxylase domain2protein suppresseshypoxia-induced endothelial cell proliferation[J].Hypertension, 2007, 49(1)：178-184.DOI：10.1161/01.HYP.0000251360.40838.Of. [17]Chan DA,Kawahara TL,Sutphin PD,et al.Tumor vasculature isregulated by PHD2・mediated angiogenesis and bone marrow-derived cell recruitmentfj].Cancer Cell,2009,15(6):527-538.DOI：10.1016/r.2009.04.010.[18]Thompson K,Chen J,Luo Q,et al.Advanced glycation end(AGE)product modification of laminin downregulates Kir4.1in retinal Mtiller cells[J/OL].PLoS One,2018,13(2):eOl30646[2018-02-04].https：//journals,/plosone/article?id=10.1371/journal, pone.0193280.DOI:10.1371/joumal.pone.0193280.(收稿日期:2018-03-04修回日期:2019-08-05)(本文编辑：杜娟)读者•作者•编者本刊对稿件的学术要求文稿须有较髙的学术价值，具有创新性、科学性、导向性和实用性。
