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２０１５年１２月第２３卷第１２期 工业催化ＩＮＤＵＳＴＲＩＡＬＣＡＴＡＬＹＳＩＳ Ｄｅｃ．２０１５Ｖｏｌ．２３ Ｎｏ．１２综述与展望收稿日期：２０１５－０５－０４；修回日期：２０１５－１２－０３ 作者简介：辛玉兵，１９８８年生，男，安徽省界首市人，硕士，研究方向为工业催化。
通讯联系人：辛玉兵。
乙炔氢氯化制氯乙烯无汞催化剂研究进展辛玉兵 ，张世刚，张变玲，张军民（陕西煤化工技术工程中心有限公司，陕西西安７１００７５）摘 要：氯乙烯是重要的化工原料，乙炔氢氯化是制取氯乙烯主要方法之一，工业上普遍采用汞催化剂，对环境污染严重，且危害人体健康。
对汞资源的过度消耗和依赖是聚氯乙烯行业发展面临的巨大障碍，开发无毒环保的非汞催化剂已成为首要解决的问题。
综述近年来乙炔氢氯化无汞催化剂的研究现状，主要包括以Ａｕ为代表的贵金属催化剂、以Ｃｕ、Ｓｎ和Ｎｉ等为代表的非贵金属催化剂以及以新兴的Ｃ－Ｎ材料为代表的非金属催化剂。
Ａｕ用作催化剂价格昂贵，不利于工业化应用。
碳氮材料具有较大的比表面积，对氯化氢具有优异的吸附性能，用于乙炔氢氯化反应具有较高活性，并具有较大的工业应用潜力，以碳氮材料为代表的非金属催化剂成为新的研究热点。
关键词：有机化学工程；氯乙烯；乙炔；氢氯化；无汞催化剂ｄｏｉ：１０．３９６９／ｊ．ｉｓｓｎ．１００８ １１４３．２０１５．１２．００４中图分类号：ＴＱ４２６．９４；ＴＱ２２２．４＋２３ 文献标识码：Ａ 文章编号：１００８ １１４３（２０１５）１２ ０９７５ ０５ＤｅｖｅｌｏｐｍｅｎｔｓｉｎｎｏｎｍｅｒｃｕｒｉｃｃａｔａｌｙｓｔｓｆｏｒｈｙｄｒｏｃｈｌｏｒｉｎａｔｉｏｎｏｆａｃｅｔｙｌｅｎｅｔｏｖｉｎｙｌｃｈｌｏｒｉｄｅＸｉｎＹｕｂｉｎｇ，ＺｈａｎｇＳｈｉｇａｎｇ，ＺｈａｎｇＢｉａｎｌｉｎｇ，ＺｈａｎｇＪｕｎｍｉｎ（ＳｈａａｎｘｉＣｏａｌＣｈｅｍｉｃａｌＴｅｃｈｎｏｌｏｇｙＥｎｇｉｎｅｅｒｉｎｇＣｅｎｔｒｅＣｏ．，Ｌｔｄ．，Ｘｉ’ａｎ７１００７５，Ｓｈａａｎｘｉ，Ｃｈｉｎａ）Ａｂｓｔｒａｃｔ：Ｖｉｎｙｌｃｈｌｏｒｉｄｅｉｓａｋｉｎｄｏｆｉｍｐｏｒｔａｎｔｃｈｅｍｉｃａｌｒａｗｍａｔｅｒｉａｌ．Ｔｈｅｈｙｄｒｏｃｈｌｏｒｉｎａｔｉｏｎｏｆａｃｅｔｙｌｅｎｅｉｓｏｎｅｏｆｔｈｅｍａｊｏｒｍｅｔｈｏｄｓｏｆｖｉｎｙｌｃｈｌｏｒｉｄｅｐｒｏｄｕｃｔｉｏｎ．Ｈｏｗｅｖｅｒ，ｍｅｒｃｕｒｉｃｃａｔａｌｙｓｔｓｕｓｅｄｉｎｔｈｅｐｒｏｃｅｓｓｏｆａｃｅｔｙｌｅｎｅｈｙｄｒｏｃｈｌｏｒｉｎａｔｉｏｎｃａｕｓｅｓｅｒｉｏｕｓｅｎｖｉｒｏｎｍｅｎｔａｌｐｏｌｌｕｔｉｏｎａｎｄｅｎｄａｎｇｅｒｈｕｍａｎｂｅｉｎｇｈｅａｌｔｈ．Ｔｈｅｅｘｃｅｓｓｉｖｅｄｅｐｅｎｄｅｎｃｅａｎｄｃｏｎｓｕｍｐｔｉｏｎｏｆｍｅｒｃｕｒｙｒｅｓｏｕｒｃｅｓｉｓａｈｕｇｅｏｂｓｔａｃｌｅ，ｗｈｉｃｈｔｈｅＰＶＣｉｎｄｕｓｔｒｙｈａｓｔｏｆａｃｅ．Ｔｈｅｒｅｆｏｒｅ，ｔｈｅｄｅｖｅｌｏｐｍｅｎｔｏｆｎｏｎ ｔｏｘｉｃａｎｄｅｎｖｉｒｏｎｍｅｎｔａｌｆｒｉｅｎｄｌｙｎｏｎｍｅｒｃｕｒｉｃｃａｔａｌｙｓｔｓｈａｓｂｅｃｏｍｅｔｈｅｐｒｉｍａｒｙｐｒｏｂｌｅｍｔｏｂｅｓｏｌｖｅｄ．Ｔｈｅｒｅｓｅａｒｃｈｓｔａｔｕｓｏｆｎｏｎｍｅｒｃｕｒｉｃｃａｔａｌｙｓｔｓｆｏｒａｃｅｔｙｌｅｎｅｈｙｄｒｏｃｈｌｏｒｉｎａｔｉｏｎｗａｓｒｅｖｉｅｗｅｄ，ｍａｉｎｌｙｉｎｃｌｕｄｉｎｇｎｏｂｌｅｍｅｔａｌｃａｔａｌｙｓｔｓｒｅｐｒｅｓｅｎｔｅｄｂｙｇｏｌｄ，ｎｏｎ ｎｏｂｌｅｍｅｔａｌｃａｔａｌｙｓｔｓｓｕｃｈａｓＣｕ，ＳｎａｎｄＮｉ，ａｎｄｎｏｖｅｌｎｏｎｍｅｔａｌｌｉｃｃａｔａｌｙｓｔｓｒｅｐｒｅｓｅｎｔｅｄｂｙＣ Ｎｍａｔｅｒｉａｌｓ．Ｇｏｌｄｕｓｅｄａｓｔｈｅｃａｔａｌｙｓｔｗａｓｅｘｐｅｎｓｉｖｅ，ｗｈｉｃｈｗａｓｎｏｔｃｏｎｄｕｃｉｖｅｔｏｉｎｄｕｓｔｒｉａｌａｐｐｌｉｃａｔｉｏｎ．ＴｈｅＣ Ｎｍａｔｅｒｉａｌｓｗｉｔｈｈｉｇｈｓｐｅｃｉｆｉｃｓｕｒｆａｃｅａｒｅａｈａｄｅｘｃｅｌｌｅｎｔａｄｓｏｒｐｔｉｏｎｐｅｒｆｏｒｍａｎｃｅｆｏｒｈｙｄｒｏｇｅｎｃｈｌｏｒｉｄｅ．Ｔｈｅｒｅｆｏｒｅ，Ｃ Ｎｍａｔｅｒｉａｌｓｕｓｅｄａｓｔｈｅｃａｔａｌｙｓｔｓｆｏｒｈｙｄｒｏｃｈｌｏｒｉｎａｔｉｏｎｏｆａｃｅｔｙｌｅｎｅｔｏｖｉｎｙｌｃｈｌｏｒｉｄｅｐｏｓｓｅｓｓｅｄｈｉｇｈａｃｔｉｖｉｔｙ，ｗｈｉｃｈｈａｄｇｒｅａｔｐｏｔｅｎｔｉａｌｉｎｃｏｍｍｅｒｃｉａｌａｐｐｌｉｃａｔｉｏｎ．ＮｏｎｍｅｔａｌｌｉｃｃａｔａｌｙｓｔｓｒｅｐｒｅｓｅｎｔｅｄｂｙＣ Ｎｍａｔｅｒｉａｌｓｂｅｃａｍｅａｎｅｗｒｅｓｅａｒｃｈｈｏｔｓｐｏｔ．Ｋｅｙｗｏｒｄｓ：ｏｒｇａｎｉｃｃｈｅｍｉｃａｌｅｎｇｉｎｅｅｒｉｎｇ；ｖｉｎｙｌｃｈｌｏｒｉｄｅ；ａｃｅｔｙｌｅｎｅ；ｈｙｄｒｏｃｈｌｏｒｉｎａｔｉｏｎ；ｎｏｎｍｅｒｃｕｒｉｃｃａｔａｌｙｓｔｄｏｉ：１０．３９６９／ｊ．ｉｓｓｎ．１００８ １１４３．２０１５．１２．００４ＣＬＣｎｕｍｂｅｒ：ＴＱ４２６．９４；ＴＱ２２２．４＋２３ Ｄｏｃｕｍｅｎｔｃｏｄｅ：Ａ ＡｒｔｉｃｌｅＩＤ：１００８ １１４３（２０１５）１２ ０９７５ ０５Copyright ©博看网. All Rights Reserved. ９７６ 工业催化 ２０１５年第１２期 氯乙烯是一种应用于高分子化工的重要单体，主要用于生产聚氯乙烯。
PYBJ15-Q24-S5-Mdate 06/24/2019page1 of 9SERIES: PYBJ15 │ DESCRIPTION: DC-DC CONVERTERFEATURES• up to 15 W isolated output• ultra wide 4:1 input voltage range • single regulated output• output short circuit, over current, over voltage protection • efficiency up to 89%• DIP and SMT mounting styles • available with or without case• 1500 Vdc isolationMODELinput voltageoutput voltageoutput currentoutput powerripple & noise 1efficiency 2typ (Vdc)range (Vdc)(Vdc)min (mA)max (mA)max (W)max (mVp-p)typ (%)PYBJ15-Q24-S3249~36 3.30450014.8510088PYBJ15-Q24-S5249~365030001510088PYBJ15-Q24-S12249~3612012501510089PYBJ15-Q24-S15249~3615010001510089PYBJ15-Q48-S34818~75 3.30450014.8510088PYBJ15-Q48-S54818~755030001510088PYBJ15-Q48-S124818~7512012501510089PYBJ15-Q48-S154818~751510001510089Notes: 1. From 5~100% load, nominal input, 20 MHz bandwidth oscilloscope, with 10 µF tantalum and 1 µF ceramic capacitors on the output. From 0~5% load, ripple and noise is <5% Vo.2. Measured at nominal input voltage, full load.3. All specifications are measured at T a=25°C, humidity < 75%, nominal input voltage, and rated output load unless otherwise specified.PART NUMBER KEYBase NumberPYBJ15 - Q XX - S XX - X XInput VoltageOutput VoltageCase:“blank” = with case O = no caseMounting Style:D = DIPM = SMTdate 06/24/2019 │page 2 of 9 CUI Inc │ SERIES: PYBJ15 │DESCRIPTION: DC-DC CONVERTERINPUTparameter conditions/description min typ max unitsoperating input voltage24 Vdc input models48 Vdc input models 91824483675VdcVdcstart-up voltage24 Vdc input models48 Vdc input models 918VdcVdcsurge voltage24 Vdc input models for 1 second max48 Vdc input models for 1 second max -0.7-0.750100VdcVdcunder voltage shutdown24 Vdc input models48 Vdc input models 5.5126.515.5VdcVdccurrent 24 Vdc input models3, 5 Vdc output models12, 15 Vdc output models727718mAmA48 Vdc input models 3.3 Vdc output models5 Vdc output models363360mAmAstart-up current24 Vdc input models48 Vdc input models 3,0001,500mAmAremote on/off (CTRL)4turn on (CTRL pin pulled low to GND (0~1.2 Vdc))turn off (CTRL pin open or pulled high (3.5~12 Vdc))input current when switched off615mAalarm indication (ALM)Valm (relative to GND), when under voltage protection isgoing to happen, and during the over voltage protectionworking status.0.2 1.2Vdc Valm (relative to GND), other working status 3.59Vdcfilter Pi filterno load power consumption0.36W Notes: 4. The voltage of the CTRL pin is referenced to input GND pin.OUTPUTparameter conditions/description min typ max unitsmaximum capacitive load53.3, 5 Vdc output models12 Vdc output models15 Vdc output models4,7001,000820μFμFμFvoltage accuracy from 0% to full load±1±2% line regulation from low line to high line, full load±0.2±0.5% load regulation6from 5% to full load±0.5±1% switching frequency7PWM mode300kHz transient recovery time25% load step change, nominal input voltage300500μstransient response deviation 25% load step change, nominal input voltage3.3, 5 Vdc output modelsall other output models±3±3±8±5%%temperature coefficient at full load±0.03%/°C Note: 5. Tested at input voltage range and full load.6. At 0~100% load, the max load regulation is ±3%.7. Value is based on full load. At loads <50%, the switching frequency decreases with decreasing load for efficiency improvement.date 06/24/2019 │ page 3 of 9CUI Inc │ SERIES: PYBJ15 │ DESCRIPTION: DC-DC CONVERTER PROTECTIONSparameterconditions/description min typmax units over voltage protection output shut down 110160%over current protection hiccup, auto recovery110180230%short circuit protectionhiccup, continuous, auto recoverySAFETY AND COMPLIANCEparameter conditions/descriptionmin typ max units isolation voltageinput to output for 1 minute at 1 mA input to case 8 for 1 minute at 1 mA output to case 8 for 1 minute at 1 mA 1,500500500Vdc Vdc Vdc isolation resistance input to output at 500 Vdc input to case 8 at 500 Vdc output to case 8 at 500 Vdc 100100100MΩMΩMΩisolation capacitance input to output, 100 kHz / 0.1 V 1,000pFsafety approvals IEC 62368-1, EN 62368-1conducted emissions CISPR32/EN55032, class B (external circuit required, see Figure 2-a) radiated emissions CISPR32/EN55032, class B (external circuit required, see Figure 2-a)ESDIEC/EN61000-4-2, contact ±6 kV , class B radiated immunity IEC/EN61000-4-3, 10 V/m, class AEFT/burst IEC/EN61000-4-4, ±2 kV , class B (external circuit required, see Figure 2-b)surgeIEC/EN61000-4-5, line-line ±2 kV , class B (external circuit required, see Figure Figure 2-b)conducted immunity IEC/EN61000-4-6, 3 Vr .m.s, class A MTBF as per MIL-HDBK-217F , 25°C 1,000,000hoursRoHSyesNote:8. Only applies to versions with case.ENVIRONMENTALparameterconditions/description min typmax units operating temperature see derating curves-4085°C storage temperature -55125°C storage humidity non-condensing595%vibration10~150 Hz, for 60 minutes on each axis 5GDERATING CURVESO u t p u t L o a d (%)60801004020120 0Temperature Derating Curve(Output Load vs. Ambient Tempearature3.3, 5 Vdc output models)O u t p u t L o a d (%)60801004020120 070Temperature Derating Curve(Output Load vs. Ambient Tempearature12, 15 Vdc output models)date 06/24/2019 │ page 4 of 9CUI Inc │ SERIES: PYBJ15 │ DESCRIPTION: DC-DC CONVERTER MECHANICALparameterconditions/descriptionmintypmaxunits dimensionsDIP without case:3.3, 5 Vdc output models: 38.70 x 27.20 x 6.20 [1.524 x 1.071 x 0.244 inch]12, 15 Vdc output models: 38.70 x 27.20 x 5.80 [1.524 x 1.071 x 0.228 inch]mm mm DIP with case:3.3, 5 Vdc output models: 39.10 x 29.50 x 6.80 [1.539 x 1.161 x 0.268 inch]12, 15 Vdc output models: 39.10 x 29.50 x 6.40 [1.539 x 1.161 x 0.252 inch]mm mm SMT without case:3.3, 5 Vdc output models: 38.70 x 27.20 x 6.20 [1.524 x 1.071 x 0.244 inch]12, 15 Vdc output models: 38.70 x 27.20 x 5.80 [1.524 x 1.071 x 0.228 inch]mm mm SMT with case:3.3, 5 Vdc output models: 39.10 x 29.50 x 6.80 [1.539 x 1.161 x 0.268 inch]12, 15 Vdc output models: 39.10 x 29.50 x 6.40 [1.539 x 1.161 x 0.252 inch]mm mm case material aluminum alloyweightwithout case 3.3, 5 Vdc output models without case 12, 15 Vdc output models with case 3.3, 5 Vdc output models with case 12, 15 Vdc output models11.08.813.811.5g g g g10 Sec. Max.Wave Soldering Time4 Sec. Max.Peak Temp. 260°C Max.Time (sec.)T e m p e r a t u r e (°C )25020015010050SOLDERABILITYparameter conditions/descriptionmin typ max units hand soldering 1.5 mm from case for 10 seconds 300°C wave soldering 9see wave soldering profile260°C reflow soldering 10see reflow soldering profileMaximum duration >217°C is 60 seconds.For actual application, refer to IPC/JEDEC J-STD-020D.1245°CNote: 9. For DIP models only. 10. For SMT models only.50100150200250245217T e m p e r a t u r e (°C )Time (sec.)60 sec max (>217°C)Peak Temp 245°CWave Soldering Proflile(DIP models)Reflow Soldering Profile(SMT models)date 06/24/2019 │ page 5 of 9CUI Inc │ SERIES: PYBJ15 │ DESCRIPTION:DC-DC CONVERTER units: mm [inch]tolerance: ±0.50[±0.020]pin section tolerance: ±0.10[±0.004]Recommended PCB LayoutTop Viewunits: mm [inch]tolerance: ±0.50[±0.020]pin section tolerance: ±0.10[±0.004]MECHANICAL DRAWING (DIP WITH CASE )Recommended PCB LayoutTop ViewMECHANICAL DRAWING (DIP WITHOUT CASE )PIN CONNECTIONS PIN Function 1+Vo 2+Vo 3+Vo 40V 50V 6NC 7ALM 8CTRL 9NC 10+Vin 11+Vin 12GND 13GND PIN CONNECTIONS PIN Function 1+Vo 2+Vo 3+Vo 40V 50V 6NC 7ALM 8CTRL 9NC 10+Vin 11+Vin 12GND 13GND 14NCNote: NC = no connectdate 06/24/2019 │ page 6 of 9CUI Inc │ SERIES: PYBJ15 │ DESCRIPTION: DC-DC CONVERTER units: mm [inch]tolerance: ±0.50[±0.020]pin section tolerance: ±0.10[±0.004]MECHANICAL DRAWING (SMT WITHOUT CASE )Recommended PCB LayoutTop Viewunits: mm [inch]tolerance: ±0.50[±0.020]pin section tolerance: ±0.10[±0.004]MECHANICAL DRAWING (SMT WITH CASE )PIN CONNECTIONS PIN Function 1+Vo 2+Vo 3+Vo 40V 50V 6NC 7NC 8ALM 9CTRL 10NC 11+Vin 12+Vin 13GND 14GND Recommended PCB LayoutTop ViewPIN CONNECTIONS PIN Function 1+Vo 2+Vo 3+Vo 40V 50V 6NC 7NC 8ALM 9CTRL 10NC 11+Vin 12+Vin 13GND 14GND 15NCNote: NC = no connectdate 06/24/2019 │page 7 of 9 CUI Inc │ SERIES: PYBJ15 │DESCRIPTION: DC-DC CONVERTERAPPLICATION CIRCUITFigure 1 Table 1Vin+Vo0V Vout(Vdc)Cin(μF)Cout(μF)3.3/5/12/1510010This series has been tested according to the following recommended circuit (Figure 1) before leaving the factory. If you want to further reduce the input and output ripple, you can increase the input and output capacitors or select capacitors of low equivalent impedance provided that the capacitance is less than the maximum capacitive load of the model.EMC RECOMMENDED CIRCUITTable 2Figure 2Recommended External Circuit ComponentsVin (Vdc)2448FUSE choose according to actual input currentC0470 µF / 50 V680 µF / 100 VC1, C2 4.7 µF / 50 V 4.7 µF / 100 VC3refer to the Cout in T able 1C4330 µF / 50 V330 µF / 100 VLCM1 4.7 µHCY1, CY22000 pF /2 kVdate 06/24/2019 │page 8 of 9 CUI Inc │ SERIES: PYBJ15 │DESCRIPTION: DC-DC CONVERTERPACKAGINGunits: mmInner Carton Size: 280 x 196 x 63 mmOuter Carton Size: 600 x 285 x 225 mmOuter Carton QTY: 288 pcsdate 06/24/2019 │ page 9 of 9CUI Inc │ SERIES: PYBJ15 │ DESCRIPTION: DC-DC CONVERTER CUI offers a two (2) year limited warranty. Complete warranty information is listed on our website.Headquarters20050 SW 112th Ave.Tualatin, OR 97062800.275.4899Fax 503.612.2383cui .com*******************rev.description date 1.0initial release06/24/2019The revision history provided is for informational purposes only and is believed to be accurate.REVISION HISTORYPYBJ15-Q24-S5-M。
辽宁省沈阳市郊联体2024~2025学年高三上学期10月月考英语试题一、阅读理解World Food Day Poster ContestIf you’re aged between 5 and 19 and wherever you live, the Food and Agriculture Organization (FAO) of the United Nations wants to hear from you! Use your imagination and create a poster showing a world where no one is left behind and everyone has access to healthy and affordable food.Rules:●The registration period will end at 12:00 on Friday, November 3.●The contest is divided into the following categories: from 5 to 8 years old, from 9 to 12 years old, from 13 to 15 years old and from 16 to 19 years old.●Participants who submit more than one poster will be disqualified.●All artworks must be original. And posters have to be drawn or painted with pens or colored pencils or be designed digitally.●Posters may or may not include the text. If the text is used, no more than 25 words will be accepted. Don’t include names, school names, age, contact information or photographic pictures of the competitors, etc.●Posters can only be sent using the registration form provided for this purpose. All fields of the entry form must be completed and once the poster design has been uploaded, the SUBMIT button must be clicked.●Only digital files in JPEG format will be accepted.Prize:●The selection committee will choose 15 posters in each category for the shortlist (决选名单) and inform them in December. Shortlisted candidates will receive a certificate for this achievement.●A jury (评委会) will choose three winning posters from each category, and these winning posters will be announced on the World Food Day website.●Winners will be promoted on FAO social media and will also receive a certificate of recognition and a surprise gift bag.1．What is a requirement for the participants?A．They must present only one poster.B．They must design their posters digitally.C．They must upload their posters on Nov. 3.D．They must provide their personal information.2．How many posters will be chosen for the shortlist in all?A．15.B．30.C．45.D．60.3．What will happen to the winners?A．They will become members of FAO.B．They will be introduced on FAO media.C．They will receive a lot of money.D．They will get many bags full of posters.At my first lesson in Chinese calligraphy, my teacher told me plainly: “Now I will teach you how to write your name. And to make it beautiful.” I felt my breath catch. I was curious.Growing up in Singapore, I had an unusual relationship with my Chinese name. My parents are ethnically Chinese, so they asked fortune tellers to decide my name, aiming for maximum luck. As a result, I ended up with a nonsense and embarrassing name: Chen Yiwen, meaning, roughly, “old”, “barley (薏米)” and “warm”.When I arrived in America for college at 18, I put on an American accent and abandoned my Chinese name. When I moved to Hong Kong in 2021, after 14 years in the States, I decided to learn calligraphy. Why not get back in touch with my heritage? I thought.In calligraphy, the idea is to copy the old masters’ techniques, thereby refining your own. Every week, though, my teacher would give uncomfortably on-the-nose assessments of my person. “You need to be braver,” he once observed. “Have confidence. Try to produce a bold stroke(笔画).” For years, I had prided myself on presenting an image of confidence, but my writing betrayed me.I was trying to make sense of this practice. You must visualize the word as it is to be written and leave a trace of yourself in it. As a bodily practice, calligraphy could go beyond its owncultural restrictions. Could it help me go beyond mine? My teacher once said to me, “When you look at the word, you see the body. Though a word on the page is two-dimensional, it contains multitudes, conveying the force you’ve applied, the energy of your grip, the arch of your spine.” I had been learning calligraphy to get in touch with my cultural roots, but what I was really seeking was a return to myself. Now I have sensed that the pleasure out of calligraphy allows me to know myself more fully.During a recent lesson, my teacher pointed at the word I had just finished, telling me: “This word is much better. I can see the choices you made, your calculations, your flow. Trust yourself. This word is yours.” He might as well have said, “This word is you.”4．What did the author initially think of her name “Chen Yiwen”?A．It was lucky so she gladly accepted it.B．She felt proud of its symbolic meaning.C．She understood the intention but still disliked it.D．Its strange pronunciation made her embarrassed.5．The author decided to learn calligraphy to ______.A．pick up a new hobby B．reconnect with her originC．gain insights into a new culture D．fit in with local community6．From the teacher’s words, the author learns that calligraphy ______.A．reflects the creator’s spirits B．comes from creative energyC．highlights the design of strokes D．depends on continuous practice7．What does the author intend to tell us?A．Appreciate what our culture offers.B．Find beauty from your inner self.C．A great teacher leads you to truth.D．We are the sum of what we create.Getting rid of old tyres (轮胎) has long been a problem. Most are thrown into landfills or piled up in storage. Energy recovery is another common method. This involves burning tyres to generate electricity or heat for industries, but that produces planet warming pollution; or we use them to repair roads, but chemicals from them might pollute the ground.Some firms, therefore, have begun exploring an alternative. One such firm is Wastefront, which owns a big tyre-recycling plant in north-east England. In a couple of years, it will be able to turn 8 million old tyres into new products, including a black liquid called TDO (轮胎衍生油).The process works by deconstructing a tyre into steel, rubber, and carbon black. After tearing down the steel, the remaining material is exposed to high temperatures in the absence of air to make the rubber change into a mix of hydrocarbon gases, and then they’re removed. What is left behind is pure carbon black. Once the removed gases cool down, a part of them liquefies (液化) into TDO. The remaining gases are to be burned to fuel the process. This creates a closed-cycle system that prevents emissions.The carbon black can be reused to make new tyres. That is of interest to tyre-makers because it helps efforts to become carbon neutral—achieving a balance between the amounts of carbon dioxide produced and the carbon dioxide removed from the atmosphere. Producing new carbon black requires burning heavy oil or coal, which lets off plenty of greenhouse gases.The recovered TDO is well-suited for making diesel (柴油). While not completely carbon-neutral, it does produce an 80-90% reduction in emissions of carbon dioxide, compared with the conventional fuel. The future market for such cleaner fuels will remain large, even though electric vehicles are on the rise. Fossil-fueled vehicles will exist for decades, particularly the big burners of diesel — trucks, which are harder to electrify. The fuel is also needed by trains and ships. So, anything that helps clean up overall emissions is useful — especially if it also eases a mountainous waste problem.8．What’s the purpose of the first paragraph?A．To analyze causes.B．To present problems.C．To reach solutions.D．To make comparisons.9．What can be inferred about the tyre-recycling process?A．Air boosts the burning of the old tyres.B．The remaining gases are emitted into the air.C．Pure carbon black is an unprocessed substance.D．TDO comes from the removed hydrocarbon gases.10．Why are tyre-makers interested in tyre-recycling?A．They hope to gain financial rewards.B．It helps reduce greenhouse emissions.C．It helps improve production efficiency.D．They hope to expand the future market. 11．What does the underlined word “it” in the last paragraph refer to?A．Diesel made from TDO.B．Clean electric energy.C．Carbon-neutral process.D．Recovered TDO from old tyres.A pair of researchers with Leibniz University of Hannover has demonstrated the means by which robots might be programmed to experience something similar to pain in animals. As part of their demonstration at last week’s IEEE International Conference on Robotics and Automation held in Stockholm, Johannes Kuehn and Sami Haddaddin showed how pain might be used in robots, by interacting with a BioTac fingertip sensor on the end of a Kuka robotic arm that had been programmed to react differently to differing amounts of pain.The idea of developing an artificial robot nervous system may seem contrary to all expectations, but Kuehn says doing so is important in the same way that it is good for humans to feel pain. “Pain is a system that protects us,” says Kuchn. When we avoid the source of pain, it helps us not get hurt. "So when robots can feel and react to pain, they will become smart enough to avoid it. The more dangerous the robot registers the threat to be, the faster it will withdraw and avoid the source of danger. Additionally, Kuehn and Haddadin say humans working alongside robots that feel pain, especially those in heavy machinery, will be protected around them.They have tested out some of their ideas using a robotic arm with a fingertip sensor that can detect pressure and temperature. It uses a robot-tissue patch (小片) modeled on human skin to decide how much pain should be felt and thus what action to take. For example, if the arm feels light pain, it slowly withdraws until the pain stops, and then returns to its original task; severe pain, meanwhile, causes the arm to go into a kind of lockdown mode until it can get help from a human operator.Such robots are likely to raise a host of questions, of course, if they become more common —if a robot acts the same way a human does when touching a hot plate, are we to believe it is truly experiencing pain? Only time will tell of course, but one thing that is evident, Kuehn and Haddadin’s work could lead to robots that are more human-like than ever.12．What do we learn about the robots in the demonstration?A．They can learn skills like animals.B．They can communicate with people.C．They have the ability to feel pain.D．They respond differently to requests. 13．What is paragraph 2 of the text mainly about ?A．The significance of teaching robots to feel pain.B．The principle of robots’ avoidance of injuries.C．The analysis of the artificial robot nervous system.D．The value of protecting human workers from injury.14．What can we learn from the example given in paragraph 3?A．The robot is smart enough to carry out different tasks.B．The robot can hardly work as well as a human operator.C．The robot can react differently based on degrees of pain.D．The robot is tolerant of changes of pressure and temperature.15．What is the author’s attitude toward Kuehn and Haddadin’s study?A．Negative.B．Doubtful.C．Unclear.D．OptimisticWays To Increase The Quality of Your LifeIt is time to do something to increase the quality of your life. Nothing can beat living an active, purposeful, successful life filled with happiness and fulfillment. 16Treat yourself.It doesn’t matter if it’s a meal out, or a visit to a theater. Make the first thing you do a treat that you have been longing for some time. 17 Treats can be free, and you can always make time.Take up a hobby.When you lead a boring life, it is great to have something to think about that takes you into another world. 18 If you love to read, devote time to just sitting with a book and losing yourself in an imaginary world. The whole point of a hobby is that it is something for you, so it doesn’t matter what it is as long as you enjoy it.19Often we lose sight of the positive, beneficial things in our lives. Everyone has things to be grateful for and making a list helps to concentrate your mind on these positives. Allow yourself a few minutes to think about your life and identify the good things.Exercise.20 Go running, or get down to the gym. Sweat out the negatives and get fit for the future.Follow the advice above and you will surely increase the quality of your life.A．Create a gratitude list.B．Doing morning exercise makes you fresh.C．Make the most of the years you have on Earth.D．Don’t make excuses about not having time or money.E．Taking exercise is an excellent way of boosting your mood.F．Hobbies are brilliant for giving you something different to do.G．Read our list of things to do now to make your life better and more enjoyable.二、完形填空A few years ago, a friend showed me a video of his young daughter taken by him. She was working hard to set her bicycle upright after it had 21 . She was increasingly 22 after several failures. I didn’t understand why her dad didn’t offer any 23 to her, but just took the video in which she 24 a lot. Eventually, the little girl succeeded. She was 25 of getting her bike back up. However, I still felt uncomfortable.I 26 his not doing his daughter a favor even when she asked him over and over for help. He asked me to 27 the video again. I wasn’t sure whether I wanted to, but I did.I started to realize that it was all my 28 . The girl never asked for help. I had 29 those requests vividly in my mind because it was I who couldn’t handle her frustration (挫败). But the young girl was managing it just fine and her dad was 30 her frustration without jumping into rescue.My anger towards my friend turned into 31 . I took a long look at my own 32 to jump in and rescue children from frustration. Sometimes, my brain“ hears” desperate requests for help when 33 there is only the expression of emotions. Stepping in to help a child who hasn’t asked for isn’t 34 ; it’s rescue where it isn’t 35 .21．A．emerged B．faded C．broken D．overturned 22．A．embarrassed B．fragile C．anxious D．envious 23．A．assurance B．assistance C．permission D．possibility 24．A．begged B．regretted C．struggled D．refused25．A．proud B．ashamed C．fond D．afraid 26．A．realized B．recalled C．analyzed D．questioned 27．A．watch B．introduce C．shoot D．upload 28．A．responsibility B．misunderstanding C．experience D．choice 29．A．recorded B．evaluated C．divided D．imagined 30．A．adding up to B．getting rid of C．putting up with D．looking forward to 31．A．admiration B．bitterness C．amusement D．criticism 32．A．hesitation B．tendency C．ambition D．promise 33．A．occasionally B．secretly C．hopefully D．actually 34．A．support B．courage C．independence D．trust 35．A．predicted B．needed C．counted D．reported三、语法填空阅读下面材料，在空白处填入适当的内容(1个单词)或括号内单词的正确形式。
NY5P Series (OTP for NY5)Single-Chip 4-bit MCU with 15~24 I/Oand 4-Ch Speech/MidiVersion 1.8Sept. 22, 2016NYQUEST TECHNOLOGY CO. reserves the right to change this document without prior notice. Information provided by NYQUEST is believed to be accurate and reliable. However, NYQUEST makes no warranty for any errors which may appear in this document. Contact NYQUEST to obtain the latest version of device specifications before placing your orders. No responsibility is assumed by NYQUEST for any infringement of patent or other rights of third parties which may result from its use. In addition, NYQUEST products are not authorized for use as critical components in life support devices/systems or aviation devices/systems, where a malfunction or failure of theRevision History1. 概述NY5P系列產品爲多功能單晶片CMOS語音合成4位元微控制器，是九齊科技爲了支援NY5A, NY5B, NY5C 系列MaskROM 產品所專門開發的崁入式EPROM架構的OTP IC (One Time Programmable)。
REQUIRED MEASUREMENTSMPS MAXX MODULAR POWER STANDING SYSTEM INVACARE POWER BASES❑IFX-20MPAVIVA FX Base for Multiple Actuator SystemHCPCS code K0861 . . . . . . . . . . . . . . . . . . . . . . . . . . . . $7,995(Bases comes standard with LiNX G-TRAC Module)Select STF (1): ❑STF185 18.5” ❑STF195 19.5”1. Seat-to-floor height is measured at the front of the seat pan based on a standard seat size.USER WEIGHT LIMITS❑U250Weight Capacity up to 250 lbs (1) . . . . . . . . . . . . . . . . .STD PERFORMANCE MOTORS❑HSMTR Performance Motors - 7.5 mph . . . . . . . . . . . . . . . . . . $1,400TRANSPORT TIE DOWN❑TRBKTS Wheelchair Transport Brackets (1) . . . . . . . . . . . . . . . . . . . .STD1. For unoccupied use onlyTIRE OPTIONS❑AB1431-314” x 3” Black Tire with Gel Foam Inserts . . . . . . . . . .STDCASTOR OPTIONS❑AB1228-38” x 2.5” Black Casters w/Solid Inlay . . . . . . . . . . . . . . N/CBATTERY TRAY TYPE❑GP24Group 24 Battery Box (1) . . . . . . . . . . . . . . . . . . . . . . . . . . . N/C1. MPS uses Group 34 BatteriesBATTERY CHARGER OPTION❑110CHARGER110 Volt Battery Charger . . . . . . . . . . . . . . . . . .N/C ❑L8900Omit Battery Charger . . . . . . . . . . . . . . . . . . . ($80)S O n eal o n e o r d e r f o r mon e p u r c h a s eo r d r o n e i n v o i c eTo ensure system is accurately configured please fill in all requiredWeight Capacity is up to 250lbs unless speci fi ed otherwiseREQUIRED INFORMATIONDate of Order: __________________Quote ❑ Order❑Dealer Name: _______________________________________________Dealer Account #: ___________PO #: ___________________________Tag _________________________________________________________Purchasing Contact: __________________________________________Phone: __________________________ Fax: _______________________E-mail: ______________________________________________________ATP/Therapist: _______________________________________________Ship to Address: _____________________________________________City: ____________________________ State: _____________________Zip: _____________________________Special Client Conditions: ____________________________________Client Gender: ❑M ❑FRESET FORMDealer Account Number: ____________________________________ PO #:_______________________________________________________ Tag: _______________________________________________________170P Obsidian Black . . . . . . . . . . . . . . . . . . . . . . N/C ❑171P Ruby Red. . . . . . . . . . . . . . . . . . . . . . N/C ❑172P Peacock Blue . . . . . . . . . . . . . . . . . . . . . N/C ❑173P Pink Flamingo . . . . . . . . . . . . . . . . . . . . . . N/C ❑174P Purple Passion . . . . . . . . . . . . . . . . . . . . . . N/C ❑175P Denim Navy . . . . . . . . . . . . . . . . . . . . . . N/C172PR Peacock Blue . . . . . . . . . . . . . . . . . . . . . . N/C ❑173PR Pink Flamingo . . . . . . . . . . . . . . . . . . . . . . N/C ❑174PR Purple Passion . . . . . . . . . . . . . . . . . . . . . . N/C ❑175PR Denim Navy . . . . . . . . . . . . . . . . . . . . . . N/C ❑176PR Lime Twist . . . . . . . . . . . . . . . . . . . . . . N/C ❑177PR Arctic Blue . . . . . . . . . . . . . . . . . . . . . . N/C ❑178PR Banana Split. . . . . . . . . . . . . . . . . . . . . . N/C ❑179PR Orange Marmalade . . . . . . . . . . . . . . . . . . . . N/C ❑180PR Morning Mist. . . . . . . . . . . . . . . . . . . . . . N/C EXPCExpandable Controller (1) HCPCS code E2377. . . . . . . . . $700Three drive functions, control through separate switch/toggle. Select switch on page 14 under multi-function electronics.❑PWHHarness Required for Expandable SystemHCPCS code E2313 . . . . . . . . . . . . . . . . . . . . . . $450❑REM211LED Expandable Remote/Joystick (2)(3) . . . . . . . . N/CThree drive functions, control of up to 6 actuators through the drive control. Not for use with specialty controls.❑REM216LED Expandable Remote/Joystick with Lights (3)(4) . . . . . . . . . . . . . . . . . . $350Three drive functions, control of up to 6 actuators through the drive control and lightoperation. Not for use with specialty controls.❑REM400Color 3.5” Touch ScreenRemote/Joystick (3)(4)(5) . . . . . . . . . . . . . . . . .$1,000 ❑SW400TGL Toggle Kit for REM400(6) . . . . . . . . . . . . . . . . $200❑REM500LiNX Color 3.5” Touch ScreenDisplay Only - No Driver Control (3)(4)(5) . . . . .$1,500Select mounting position❑R5MR Right❑R5ML Left1. This item is required when ordering power tilt, power recline, and power elevating legrest together OR when ordering an Alternative Drive Control2. Not available with lights and indicators3. Must choose EXPC Expandable Controller and PWH Harness.4. Can control lighting, must choose lighting package separately.5. May also be used as display for specialty controls, choose specialty controls separately.6. Adds 2 toggle switches to REM400.OUT500 Output Module . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .$500❑IN500HLiNX 9 Pin Input Modulefor Head Array (1)(2)(3)HCPCS code E2325 . . . . . . . . . . . . . . . . . . . .$1,500❑IN500LiNX 9 Pin Input Modulewith Sip-N-Puff Nozzle (1)(2)(3)HCPCS code E2328 . . . . . . . . . . . . . . . . . . . .$1,500❑PKG32666Therafin Sip-N-Puff Breath Tube Kit . . . . . . $380HCPCS code E23261. Only one input module per chair, requires REM400 or REM500 for compatibility.2. Input module also required for any 9-pin specialty control.3. 9 pin specialty control and Sip-N-Puff cannot both be used together.LIGHTS(1) . . . . . . . . . . . . . . . . . . . . . .$7001. Must order REM216, REM400 or REM500FR Fixed Joystick Mounting - Right . . . . . . . . . . . . . . . . . . . . . . . .STD❑FL Fixed Joystick Mounting - Left . . . . . . . . . . . . . . . . . . . . . . . . . .STD ❑SAQR Motion Height Adjustable Swing-AwayQuad Link (Right Hand) HCPCS code E1028 . . . . . . . . $235❑SAQL Motion Height Adjustable Swing-AwayQuad Link (Left Hand) HCPCS code E1028 . . . . . . . . . $235ACU(1) . . . . . . . . . . . . . . . . .$900Select mounting position❑RIGHT-ACU Right❑LEFT-ACU Left1. Requires Expandable Controller.CREM HCPCS code E2373❑CREM-LFLiNX Compact Remote Low ForceHCPCS code E2373 . . . . . . . . . . . . . . . . . . . . . .$1,500LAK LiNX Access Key (1) . . . . . . . . . . . . . . . . . . . $100❑MUSB Motion Dual USB Charger . . . . . . . . . . . . .N/C1. Required for programmingPC101A Bodypoint U Shaped Handle 3”(1) . . . . . . . $120❑PC102A Bodypoint U Shaped Handle 4”(1) . . . . . . . $120❑PC107A Bodypoint Rubber Dome (1) . . . . . . . . $120❑PC110AGrooved Mushroom Joystick Handle 3/16” Stem (1) . . . . . . . . . . . . . . . . . . . . . . $120❑1560T Handle Flexible JoystickExtension (1) . . . . . . . . . . . . . . . . . . . . . . . . $120❑1561 Straight Hangle Flexible JoystickExtension (1) . . . . . . . . . . . . . . . . . . . . . . . . . $120❑1826 Chin Cup (1) . . . . . . . . . . . . . . . . . . . . . . . $1201. To remove/disengage the joystick knob from the REM400 Remote pull straight up on the joystick (DO NOT TWIST) otherwise damage may occur and may void the warranty.Dealer Account Number: ____________________________________PO #:_______________________________________________________Tag: _______________________________________________________☑ULMTREUltra Low Maxx CG Tilt (45°) & Power Recline (170°) w/Extended Shear Reduction(ESR)HCPCS code E1007 . . . . . . . . . . . . . . . . . . . .$10,795☑PSMTREMPS Power Stand Module forTilt/Recline/ESR (1)HCPCS code E2301 . . . . . . . . . . . . . . . . . $10,2501. Standard with upper and lower positioning straps: padded,removable chest bar, removable and height and depth adjustable knee blocks.☑ESM77” Power Adjustable Seat Height Module (1)HCPCS code E2300Weight Capacity up to 250lbs max. . . . . . . . . . . $1,9951. With Tilt/Recline/ESR/Stand legrest will extend 13 ° during seat elevation.❑SSW16 16” Wide (Adjustable from 16” to 21”) ................N/C ❑SSW1717” Wide (Adjustable from 16” to 21”) ................N/C ❑SSW18 18” Wide (Adjustable from 16” to 21”) ................N/C ❑SSW19 19” Wide (Adjustable from 16” to 21”) ................N/C ❑SSW2020” Wide (Adjustable from 16” to 21”) ................N/C❑SSD16 16” Deep (Adjustable from 16” to 20”) ................N/C ❑SSD17 17” Deep (Adjustable from 16” to 20”) ................N/C ❑SSD18 18” Deep (Adjustable from 16” to 20”) ................N/C ❑SSD19 19” Deep (Adjustable from 16” to 20”) ................N/C ❑SSD2020” Deep (Adjustable from 16” to 20”) ................N/CMatrx PS Seat Cushion 16” - 20” wide/reversable coverHCPCS code E2605 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $345❑PS1616❑PS1618❑PS1620❑PS1716❑PS1718❑PS1720❑PS1816❑PS1818❑PS1820 ❑PS2016❑PS2018❑PS2020Matrx PSP Seat Cushion 16” - 20” wide/reversable cover HCPCS code E2607 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $395❑PSP1616❑PSP1618❑PSP1620❑PSP1716❑PSP1718❑PSP1720❑PSP1816❑PSP1818❑PSP1820 ❑PSP2016❑PSP2018❑PSP2020Matrx Vi Seat Cushion 16” - 20” wideHCPCS code E2607 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .$425❑MA1616-VI ❑MA1618-VI ❑MA1620-VI ❑MA1716-VI ❑MA1718-VI ❑MA1720-VI ❑MA1816-VI ❑MA1818-VI ❑MA1820-VI ❑MA2016-VI❑MA2018-VI ❑MA2020-VIMatrx Libra Seat Cushion 16” - 20” wideHCPCS code E2624 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $485❑LC1616❑LC1618❑LC1620❑LC1716 ❑LC1718❑LC1720❑LC1816❑LC1818 ❑LC1820 ❑LC1916❑LC1918❑LC1920❑LC2016❑LC2018❑LC2020Matrx Libra Seat Cushion 22” deep HCPCS code E2624 . . . . $595❑LC1622❑LC1722❑LC1822❑LC1922❑LC2022❑LC2122Matrx Libra Adjust Seat Cushion 16” -20” wideHCPCS code E2624 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $625❑LC1616-ADJ ❑LC1618-ADJ ❑LC1620-ADJ ❑LC1716-ADJ ❑LC1718-ADJ ❑LC1720-ADJ ❑LC1816-ADJ ❑LC1818-ADJ ❑LC1820-ADJ ❑LC1916-ADJ ❑LC1918-ADJ ❑LC1920-ADJ ❑LC2016-ADJ ❑LC2018-ADJ ❑LC2020-ADJ❑OCCC “ON-CHAIR” Cushion Credit (1) . . . . . . . . ($90)1. Not available on Matrx PS or PSP Cushions.❑SFLF Spacetex Fabric Option for Libra Cushion. . . N/C ❑ICFLInfection Control Fabric Upgrade forLibra Cushion . . . . . . . . . . . . . . . . . . . . . $50❑FFVFusion Fabric Upgrade for Matrx Vi Cushion ..$150❑OCUMA Onyx Fabric Upgrade for Matrx Vi Cushion ...$100❑SFVSSmooth side Startex Fabric Upgrade forMatrx Vi Cushion . . . . . . . . . . . . . . . . . . . . . . . .$50❑SFVFFabric side Startex Fabric Upgrade forMatrx Vi Cushion . . . . . . . . . . . . . . . . . . . . . . . .$50NOTE: Systems Include Seat Pan, Back Pan, and Standard Armrests. They are designed for use with a 2”- 3” cushion☑Section marked are required with the MPS Standing SystemType: ___________________________________________________Specialty Control Mount:❑Right ❑Left Specify __________________________Display Mount:❑Right ❑Left Specify__________________________Mode Switch Mount:❑Right ❑Left Specify__________________________On/Off Mount:❑Right ❑Left Specify __________________________List Other: ________________________________________Specify Mounting Location: ____________________________Meshtex Infection Control OnyxStartex Spacetex CushionMeshtexStartexInfectionSpacetexOnyxFusionLibra/Adjust N/A STD $50N/C N/A N/A PS/PSP N/A STD -ReversibleSTD -ReversibleN/A N/A N/A ViSTD$50$50N/A$100$150FusionBELT48Push Button Style Lap Belt, Length 48” . . . . . ❑BELT60 Push Button Style Lap Belt, Length 60” . . . . .STD ❑BELT71 Push Button Style Lap Belt, Length 71” . . . . .STD❑PLB2B odypoint Padded Lap Belt 2 Point (1) HCPCS code E0978 . . . . . . . . . . . . . . . . . . . .$190❑PLB4Bodypoint Padded Lap Belt 4 Point (1)HCPCS code E0978 . . . . . . . . . . . . . . . . . . . .$2351. 67” length only optionPCS Padded Chest Strap 2 point (1) HCPCS code E0978 STDHCPCS code E0960❑MFUSBP Monoflex, Underarm RLS S(3” x 15.5”) . $195❑MFUM BP Monoflex, Underarm RLS M(4” x 18.25”) $195❑MFUL BP Monoflex, Underarm RLS L(4.5” x 21.5”) .$195❑MFCS BP Monoflex, Center RLS S(2.5” x 15.5”) . . $195❑MFCM BP Monoflex, Center RLS M(3.25” x 18.25”) $195MFCLBP Monoflex, Center RLS L(3.5” x 21.5”) . . .$195FWCBLFoam Wrapped Chest Bar - Mount Left ❑FWCBR Foam Wrapped Chest Bar - Mount Right . . . .STD ❑FPCBL Flat Pad Chest Bar - S/A Mount Left . . . . . .$450❑FPCBRFlat Pad Chest Bar - S/A Mount Right . . . . .$4501. Left/Right Mount indicates the swing away point. Should be opposite the joystick side to avoid interference.HALTLHeight Adjustable Lap Tray (21”W x 12”D)in Clear Polycarbonate Plastic - Left Mnt. . .$750❑HALTRHeight Adjustable Lap Tray (21”W x 12”D)in Clear Polycarbonate Plastic - Right Mnt. .$7501. Left/Right Mount indicates the swing away point. Should be opposite the joystick side to avoid interference.ESP6 ❑ESP10 Matrx Elan Standard Pad 10” ...............$235❑ESP14 Matrx Elan Standard Pad 14” ...............$235❑EOP9 Matrx Elan Occipital Pad 9” ..................$235❑EOP12 Matrx Elan Occipital Pad 12” ................$235❑E4PTSM Matrx Elan 4-Point Pad 9”W x 7”H .........$325❑E4POINT Matrx Elan 4-Point Pad 11”W x 10”H .....$325❑ESP6-ICMatrx Elan Standard Pad 6” withInfection Control ...................................$235 ❑ESP10-IC Matrx Elan Standard Pad 10” withInfection Control ...................................$235 ❑ESP14-ICMatrx Elan Standard Pad 14” with InfectionInfectionControl ...................................$235❑EOP9-IC Matrx Elan Occipital Pad 9” with Infection Infection Control ..................................$235EOP12-IC Control.................................................$235 ❑E4PTSM-IC Matrx Elan 4-Point Pad 9”W x 7”H with Infection Control ..........................$325❑E4POINT-IC Matrx Elan 4-Point Pad 11”W x 10”H with Infection Control ...........................$3251. If mounting on PB Elite must order removable hardwareMCSH Motion Concepts Standard 1. Unless selecting a “Removable” hdwr option, this Headrest will come standard w/ Fixed Straight Mounting Hardware (non-removable)FM Fixed Mounting (non-removable) (1) ....... N/C ❑MEHWElan Multi-Axis Removable HDWHCPCS code E1028 .......................................$220❑MEHWEXT Elan Extended Headrest Hardware Multi-Axis Removable HCPCS code E1028 .....$295❑MAHUMotion Concepts Multi-Axis Rem.HDWHCPCS code E1028 .......................................$195❑OHROMIT: Headres t ..............................................N/C1. Only compatible w/Standard Rehab & High Back Models. All other head rests REQUIRE an upgrade to Removable Hardware.FBR20 20” FBR21 21” FBR22 22” FBR23 23” FBR24 24”❑FBR25 25” ❑FBR26 26” ❑FBR27 27” ❑FBR28 28”1. 8” Gap from the seat pan to the bottom of back pan is recommended.2. Finished back height is measured from seat pan to top of backrest.SRB ❑SS Additional Super Soft/HR Foam (1) . . . . . .$100 ❑MFU Matrx Fabric Upcharge . . . . . . . . . . . . .$100❑PIPF Flat Planar Interface Plate . . . . . . . . . .$1251. Additional foam added may impact seat depthHCPCS code E2620 ❑HB1616 ❑HB1618 ❑HB1620 ❑HB1716❑HB1718 ❑HB1720 ❑HB1816 ❑HB1818 ❑HB1820 ❑HB1916 ❑HB1918 ❑HB1920❑HB2016❑HB2018❑HB2020Matrx Elite Back 16” - 20” wide (3” Contour) HCPCS code E2620 $625❑PBE1614 ❑PBE1616 ❑PBE1618 ❑PBE1620 ❑PBE1714 ❑PBE1716 ❑PBE1718 ❑PBE1720 ❑PBE1814 ❑PBE1816 ❑PBE1818 ❑PBE1820 ❑PBE1914 ❑PBE1916 ❑PBE1918 ❑PBE1920❑PBE2014 ❑PBE2016 ❑PBE2018❑PBE2020Matrx Elite TR Back 15” - 20” wide (3” Contour) HCPCS code E2620$650 ❑PBE1614-TR❑PBE1616-TR❑PBE1618-TR ❑PBE1620-TR ❑PBE1714-TR ❑PBE1716-TR❑PBE1718-TR❑PBE1720-TR ❑PBE1814-TR❑PBE1816-TR❑PBE1818-TR❑PBE1820-TR ❑PBE1914-TR ❑PBE1916-TR❑PBE1918-TR❑PBE1920-TR ❑PBE2014-TR ❑PBE2016-TR❑PBE2018-TR❑PBE2020-TRMatrx Elite E2 Back 16” - 20” wide/14”/16”H(3” Contour)HCPCS code pending . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $625❑E2S1614❑E2S1616❑E2S1714❑E2S1716❑E2S1814❑E2S1816❑E2S1914 ❑E2S1916❑E2S2014❑E2S2016Matrx Elite E2 Back 16” - 20” wide/18”/20”H(3” Contour) HCPCS code pending . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $645 ❑E2S1618❑E2S1620 ❑E2S1718❑E2S1720 ❑E2S1818❑E2S1820❑E2S1918❑❑E2S2018❑E2S2020Matrx Elite E2 Deep Back 16” - 20” wide/14”/16”H (6” Contour) HCPCS code E2620 . . . . . . . . . . . . . . . . . . . . . . . . . . . . $755 ❑E2D1614❑E2D1616❑E2D1714❑E2D1716❑E2D1814❑E2D1816❑E2D1914 ❑E2D1916❑E2D2014❑E2D2016Matrx Elite E2 Deep Back 16” - 20” wide/18”/20”H (6” Contour)HCPCS code E2620 . . . . . . . . . . . . . . . . . . . . . . . . . . . . $775 ❑E2D1618❑E2D1620❑E2D1718❑E2D1720❑E2D1818❑E2D1820❑E2D1918❑E2D1920❑E2D2018❑E2D2020Matrx Elite Deep Back 14” - 20” wide (6” Contour)HCPCS code E2620 . . . . . . . . . . . . . . . . . . . . . . . . . . . . .$760❑EDB1614 ❑EDB1616❑EDB1618❑EDB1620❑EDB1714 ❑EDB1716❑EDB1718❑EDB1720❑EDB1814 ❑EDB1816❑EDB1818❑EDB1820❑EDB1914❑EDB1916❑EDB1918❑EDB1920❑EDB2014 ❑EDB2016 ❑EDB2018❑EDB2020Matrx PB Posture Back 14” - 20” wide (5” Contour)HCPCS code E2615. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .$625 ❑MPB1412 ❑MPB1416 ❑MPB1612 ❑MPB1616 ❑MPB1620 ❑MPB1712 ❑MPB1716 ❑MPB1720❑MPB1812❑MPB1816❑MPB1820❑MPB2012❑MPB2016❑MPB2020Matrx PB Posture Back Deep 14” - 20” wide (7” Contour)HCPCS code E2615. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . $645 ❑PBD1612 ❑PBD1616 ❑PBD1660 ❑PBD1712 ❑PBD1716 ❑PBD1720 ❑PBD1812 ❑PBD1816❑PBD1820❑PBD2012 ❑PBD2016 ❑PBD2020❑OCBC “ON-CHAIR” Matrx Back Credit . . . . . . . . . ($125)❑EBSS Super Soft Foam for Elite Back Upgrade . . . . $100❑FFUHB Fusion Fabric Upgrade for High Backs . . . . . . $100❑OCUHB Onyx Fabric Upgrade for High Backs . . . . . . . $100❑WSCU Infection Control Cover for Elite/PB Backs . . . $100purchased with back❑WSC Infection Control Cover for Elite/PB Backs . . . $150purchased with without backSCCMFBA Stander Cantilever Cane MountedFlip Back Armrest 9.5”-13” H . . . . . . . . . . .STD❑ATFL Left Full . . . . . . . . . . . . . . . . . . . . . . . . .STD ❑ATDL Left Desk . . . . . . . . . . . . . . . . . . . . . . . .STD ❑ATFR Right Full . . . . . . . . . . . . . . . . . . . . . . . . . . .STD ❑ATDR Right Desk . . . . . . . . . . . . . . . . . . . . . . . . . .STD❑SAPFL Left Full (2.25” x 14”) . . . . . . . . . . . . . . . . .STD ❑SAPDL Left Desk (2.25” x 10”) . . . . . . . . . . . . . . . .STD ❑SAPFR Right Full (2.25” x 14”) . . . . . . . . . . . . . . . . . .STD ❑SAPDR Right Desk (2.25” x 10”) . . . . . . . . . . . . . . . . .STD Modular Arm Pad - Left(1)❑MAPTFL Left Tray Full (14”) . . . . . . . . . . . . . . . . . . . . .$55❑MAPTDL Left Tray Desk (10”) . . . . . . . . . . . . . . . . . . . .$55 Select Pad Insert below:❑ISSF L Iskin - Integrated soft skin foam❑SCVFL Startex Covered Visco foamModular Arm Pad - Right(1)❑MAPTFR Right Tray Full (14”) . . . . . . . . . . . . . . . . . . . .$55❑MAPTDR Right Tray Desk (10”) . . . . . . . . . . . . . . . . . . .$55 Select Pad Insert below:❑ISSFR Iskin - Integrated soft skin foam❑SCVFR Startex Covered Visco foam4-way Stretch PolyesterMeshtex Infection ControlOnyxNEW NEW NEW NEWFlat Multi Position Arm Pads❑MPAFLLeft Full (14”) . . . . . . . . . . . . . . . . . . . . . . . . .$55❑MPADL Left Desk (10”) . . . . . . . . . . . . . . . . . . . . . . . .$55❑MPAFR Right Full (14”) . . . . . . . . . . . . . . . . . . . . . . . .$55❑MPADRRight Desk (10”) . . . . . . . . . . . . . . . . . . . . . . .$55Gel Pads❑GAPNL Narrow Left Full (2” x 12”) . . . . . . . . . . . . . . .$75❑GAPNR Narrow Right Desk (2” x 12”) . . . . . . . . . . . . .$75❑GAPWL Wide Left Full (3.5” x 12”) . . . . . . . . . . . . . . . .$75❑GAPWR Wide Right Desk (3.5” x 12”) . . . . . . . . . . . . . .$75 ❑GAPLL Long Left Full (3.5” x 14”) . . . . . . . . . . . . . . . .$90❑GAPLRLong Right Desk (3.5” x 14”) . . . . . . . . . . . . . .$90Arm Troughs❑EATL Ergonomic Arm Trough - Left HCPCS code E2209 . .$85❑EATR Ergonomic Arm Trough - Right HCPCS code E2209 .$85❑FHPL Flat Hand Pad - Left (2) HCPCS code K0108 . . . . . . . . .$55❑FHPR Flat Hand Pad - Right (2) HCPCS code K0108 . . . . . . . .$551. Requires interchangeable pad insert.2. Must order with ergomonic arm trough.Left Fixed Mount Lateral Trunk Support (1)Select Left Trunk Support Size ❑LATXL Size XS (3.25” x 4.25”) . . . . . . . . . . . $100❑LATSL Size S (3.5” x 5.25”) . . . . . . . . . . . . . $100❑LATML Size M (3.75” x 5.75”) . . . . . . . . . . . $100❑LATLL Size L (4.25” x 6.5”) . . . . . . . . . . . . . $100Right Fixed Mount Lateral Trunk Support (1Select Right Trunk Support Size❑LATXR Size XS (3.25” x 4.25”) . . . . . . . . . . . $100❑LATSR Size S (3.5” x 5.25”) . . . . . . . . . . . . . $100❑LATMR Size M (3.75” x 5.75”) . . . . . . . . . . . $100❑LATLR Size L (4.25” 6.5”) . . . . . . . . . . . . . . $1001. These laterals are not available with Matrx PB, PB Elite Deep, and PB Deep Backs.❑SALATL Left MAXX Style Swing Away HDW (1) . . . $195Select Left Trunk Support Size❑SALATR Right MAXX Style Swing Away HDW (1) . . . $195Select Right Trunk Support Size❑ATLL Additional Telescoping Link - Left (2) . . . $75❑ATLRAdditional Telescoping Link - Right (2) . . $751. These laterals are not available with Matrx PB, PB Elite Deep, and PB Deep Backs and come standard with 1” telescoping link which gives 0-2.75” medial offset.2. The amount of offset available may be impacted by back thickness.❑E2FLL Matrx E2 Fixed Laterals-Left (6.5x5”)(1) ........$145❑E2FLR Matrx E2 Fixed Laterals-Right (6.5x5”)(1) .........$145❑PBSSL Matrx Small Lateral Fixed-Left (3x5.5”) .......$100❑PBSSR Matrx Small Lateral Fixed-Right (3x5.5”) ........$100❑PBLSL Matrx Standard Lateral Fixed-Left (7.5x5”) .$100❑PBLSR Matrx Standard Lateral Fixed-Right (7.5x5”)$100❑PBOLL Matrx Offset Lateral Fixed Left . . . . . . . .$110❑PBOLRMatrx Offset Lateral Fixed Right . . . . . .$1101. Only available with the E2 BackrestsHCPCS code E0956❑EPADXL Size XS (3.25x4.25”) .............................$100❑EPADSL Size S (3.5x5.25”) ................................$100❑EPADML Size M (3.75x5.75”) .............................$100❑EPADL L Size L (4.25x6.5”) ................................$100Matrx Lateral Trunk Support Right (1) HCPCS code E0956❑EPADXR Size XS (3.25x4.25”) .............................$100❑EPADSR Size S (3.5x5.25”) ................................$100❑EPADMR Size M (3.75x5.75”) .............................$100❑EPADLR Size L (4.25x6.5”) ................................$1001. Must choose swing away hardware belowLeft HCPCS code E1028 . . . . . . . . . . . . . . . . .$195❑SAHEBRMatrx Elite Swing Away HardwareRight HCPCS code E1028 . . . . . . . . . . . . . . .$195❑OSAHL Matrx Offset Elite Swing AwayHardware Left HCPCS code E1028 . . . . . . . . .$195❑OSAHRMatrx Offset Elite Swing AwayHardwareRight HCPCS code E1028 . . . . . . .$195HCPCS code E0956Select Pad Size and mounting position at Hip:❑HSPXLH Size XS (5.5” W x 4” H) mounted at Hip . . .$120❑HSPSLH Size S (7“W x 6”H) mounted at Hip . . . . . .$120❑HSPMLH Size M (9” W x 4”H) mounted at Hip . . . . .$120❑HSPLLH Size L (13” W x 4”H) mounted at Hip . . . . .$120Select Pad Size and mounting position at Knee:❑HSPXLK Size XS (5.5”W x 4” H) mounted at Knee . . .$120❑HSPSLK Size S (7“W x 6” H) mounted at Knee . . . . .$120❑HSPMLK Size M (9”W x 4”H) mounted at Knee . . . .$120❑HSPLLK Size L (13”W x 4”H) mounted at Knee . . . . .$120Lateral Hip Support with Fixed Mounting Hardware Right(1)HCPCS code E0956Select Pad Size and mounting position:❑HSPXRH Size XS (5.5”W x 4”H) mounted at Hip . . . .$120❑HSPSRH Size S (7“W x 6”H) mounted at Hip . . . . . .$120❑HSPMRH Size M (9”W x 4”H) mounted at Hip . . . . . .$120❑HSPLRH Size L (13”W x 4”H) mounted at Hip . . . . . .$120Select Pad Size and mounting position at Knee:❑HSPXRK Size XS(5.5”W x 4”H) mounted at Knee . . $120❑HSPSRK Size S (7“W x 6”H) mounted at Knee . . . . .$120❑HSPMRK Size M (9”W x 4”H) mounted at Knee . . . . .$120❑HSPLRK Size L (13”W x 4”H) mounted at Knee . . . .$1201. Must choose swing away hardware below if required.❑LOHL Left . . . . . . . . . . . . . . . . . . . . . . . . . . . .$195❑LOHR Right . . . . . . . . . . . . . . . . . . . . . . . . . . .$195MAXX Style Quick Release, Removable, Multi-Axis Mounting Hardware for Hip Supports HCPCS code E1028Select mounting position:❑MHSHLH L eft mounted at Hip . . . . . . . . . . . . . . . . .$215❑MHSHLK Left mounted at Knee . . . . . . . . . . . . . . . .$215❑MHSHRH Right mounted at Hip . . . . . . . . . . . . . . . .$215❑MHSHRK Right mounted at Knee . . . . . . . . . . . . . . .$215Extended Maxx Style Quick Release, Removable, Multi-AxisMounting Hardware for Hip Supports (1) HCPCS code E1028Select mounting position:❑EMQHLH Left mounted at Hip . . . . . . . . . . . . . . . . .$215❑EMQHLK Left mounted at Knee . . . . . . . . . . . . . . . .$215❑EMQHRH Right mounted at Hip . . . . . . . . . . . . . . . .$215❑EMQHRK Right mounted at Knee . . . . . . . . . . . . . . . . .$2151. Recomended when finished seat cushion thickness will be greater then 3.5” high.BDCPower Elevating BDC Belt Drive CenterMount Articulating Foot Platform (1)(2)(3)HCPCS code K0108 . . . . . . . . . . . . . . . . . . . . . .$3,295..Select seat pan to footplate:❑SPTF22 8” - 12” . . . . . . . . . . . . . . . . . . . . . . . . . N/C ❑SICP Individual Calf Pads (5.5”H x 4”W) . . . . . . . STDSelect seat pan to footplate:❑SPTF20 10” -13/14” . . . . . . . . . . . . . . . . . . . . . . N/C ❑SPTF21 13” -16/17” . . . . . . . . . . . . . . . . . . . . . . N/C ❑LICP Individual Calf Pads (7.5”H x 6”W) . . . . . . . STD1. The BDC Belt Drive is required with the MPS Standing System.2. With 18.5” seat-to-floor selected the maximum seat pan to footplate is 13”, with 19.5” seat-to-floor height selected the seat pan to footplate is 14”.3. With 18.5” seat-to-floor selected the maximum seat pan to footplate is 16”, with 19.5” seat-to-floor height selected the seat pan to footplate is 17”.Footplate Option:❑IFSL Small - (5” x 7.5” deep) - Left ....................$165❑IFSR Small - (5” x 7.5” deep) - Right ...................$165❑IFML Medium - (5.5” x 9.5” deep) - Left .............$165❑IFMR Medium - (5.5” x 9.5” deep) - Right ............$165❑IFLL Large - (6” x 11.5” deep) - Left ...................$165❑IFLR Large - (6” x 11.5” deep) - Right .................$165MKBDepth and Angle Adjustable Mounting Hardware (2) . . . . . . . . . . . . . . . . . STD❑EKBModular Knee Blocks with EccentricBolster Mounting Hardware . . . . . . . . . . . $250(Allows individual adjustment of knee blocks toaccomodate leg discrepancies)Select pad size for above Hardware option ❑10P 10” Pad for Knee Block ❑8P 8” Pad for Knee Block ❑6P 6” Pad for Knee Block1. Knee blocks are removable and stored on the side of the chair when not in use.2. 1.5” of height adjustment and 3” of depth adjustment and 2” of width independent adjustment.。
基金项目：泸州市人民政府西南医科大学科技战略合作项目（２０２１ＬＺＸＮＹＤ Ｚ０７，２０２１ＬＺＸＮＹＤ Ｊ２６）通信作者：于风旭，Ｅ ｍａｉｌ：ｙｕｌｕｃｈｕａｎ＠１６３．ｃｏｍ·论著·血管紧张素Ⅱ通过抑制人心房成纤维细胞ＢＫＣａ通道诱导心房纤维化贾春森 李磊 李劲平 谭宏伟 周伟 聂永梅 于风旭（西南医科大学附属医院心脏大血管外科，四川泸州６４６０００）【摘要】目的 探讨在血管紧张素Ⅱ（ＡｎｇⅡ）诱导心房纤维化的过程中，大电导钙激活钾通道（ＢＫＣａ通道）的作用机制。
方法 通过组织块贴壁法获取原代人心房成纤维细胞，使用免疫荧光染色进行鉴定。
用浓度为５００ｎｍｏｌ／Ｌ的ＡｎｇⅡ处理人心房成纤维细胞２４ｈ，实时荧光定量ＰＣＲ与蛋白质印迹法用于检测处理前后纤维化标志基因α 平滑肌肌动蛋白（α ＳＭＡ）、胶原蛋白Ⅰ（ｃｏｌｌａｇｅｎⅠ）和胶原蛋白Ⅲ（ｃｏｌｌａｇｅｎⅢ），以及ＢＫＣａ通道的α与β亚基的ｍＲＮＡ和蛋白表达水平，全细胞膜片钳技术检测ＡｎｇⅡ处理前后的ＢＫＣａ通道的电流变化。
结果 （１）人心房成纤维细胞经ＡｎｇⅡ处理后，α ＳＭＡ、ｃｏｌｌａｇｅｎⅠ和ｃｏｌｌａｇｅｎⅢ的ｍＲＮＡ和蛋白表达水平升高；（２）经过ＡｎｇⅡ处理后，ＢＫＣａ通道α及β亚基ｍＲＮＡ和蛋白表达水平降低；（３）人心房成纤维细胞存在功能正常的ＢＫＣａ通道，具有电压依赖性；（４）人心房成纤维细胞ＢＫＣａ通道的宏观电流幅度在经ＡｎｇⅡ处理后降低；（５）在人心房成纤维细胞上过表达ＢＫＣａ通道α亚基后，纤维化标志物α ＳＭＡ、ｃｏｌｌａｇｅｎⅠ和ｃｏｌｌａｇｅｎⅢ的表达受到了明显抑制。
结论 ＡｎｇⅡ可能通过抑制人成纤维细胞ＢＫＣａ通道的表达和功能来诱导人心房成纤维细胞的纤维化，并最终导致心房纤维化。
【关键词】心房纤维化；血管紧张素Ⅱ；人心房成纤维细胞；大电导钙激活钾通道【ＤＯＩ】１０ １６８０６／ｊ．ｃｎｋｉ．ｉｓｓｎ．１００４ ３９３４ ２０２３ １１ ０２０ＡｎｇｉｏｔｅｎｓｉｎⅡＩｎｄｕｃｅｓＡｔｒｉａｌＦｉｂｒｏｓｉｓｂｙＩｎｈｉｂｉｔｉｎｇＢＫＣａＣｈａｎｎｅｌｉｎＨｕｍａｎＡｔｒｉａｌＦｉｂｒｏｂｌａｓｔＪＩＡＣｈｕｎｓｅｎ，ＬＩＬｅｉ，ＬＩＪｉｎｐｉｎｇ，ＴＡＮＨｏｎｇｗｅｉ，ＺＨＯＵＷｅｉ，ＮＩＥＹｏｎｇｍｅｉ，ＹＵＦｅｎｇｘｕ（ＤｅｐａｒｔｍｅｎｔｏｆＣａｒｄｉｏｖａｓｃｕｌａｒＳｕｒｇｅｒｙ，ＴｈｅＡｆｆｉｌｉａｔｅｄＨｏｓｐｉｔａｌｏｆＳｏｕｔｈｗｅｓｔＭｅｄｉｃａｌＵｎｉｖｅｒｓｉｔｙ，Ｌｕｚｈｏｕ６４６０００，Ｓｉｃｈｕａｎ，Ｃｈｉｎａ）【Ａｂｓｔｒａｃｔ】Ｏｂｊｅｃｔｉｖｅ Ｔｏｉｎｖｅｓｔｉｇａｔｅｔｈｅｍｅｃｈａｎｉｓｍｏｆｌａｒｇｅｃｏｎｄｕｃｔａｎｃｅｃａｌｃｉｕｍ ａｃｔｉｖａｔｅｄｐｏｔａｓｓｉｕｍｃｈａｎｎｅｌ（ＢＫＣａ）ｉｎａｎｇｉｏｔｅｎｓｉｎⅡ（ＡｎｇⅡ） ｉｎｄｕｃｅｄａｔｒｉａｌｆｉｂｒｏｓｉｓ．Ｍｅｔｈｏｄｓ Ｐｒｉｍａｒｙｈｕｍａｎａｔｒｉａｌｆｉｂｒｏｂｌａｓｔｓｗｅｒｅｏｂｔａｉｎｅｄｂｙｔｉｓｓｕｅｂｌｏｃｋａｔｔａｃｈｍｅｎｔｍｅｔｈｏｄａｎｄｉｄｅｎｔｉｆｉｅｄｂｙｉｍｍｕｎｏｆｌｕｏｒｅｓｃｅｎｃｅｓｔａｉｎｉｎｇ．ＨｕｍａｎａｔｒｉａｌｆｉｂｒｏｂｌａｓｔｓｗｅｒｅｔｒｅａｔｅｄｗｉｔｈＡｎｇⅡ（５００ｎｍｏｌ／Ｌ）ｆｏｒ２４ｈ．Ｒｅａｌ ｔｉｍｅｆｌｕｏｒｅｓｃｅｎｔｑｕａｎｔｉｔａｔｉｖｅＰＣＲａｎｄＷｅｓｔｅｒｎｂｌｏｔｗｅｒｅｕｓｅｄｔｏｄｅｔｅｃｔｔｈｅｍＲＮＡａｎｄｐｒｏｔｅｉｎｅｘｐｒｅｓｓｉｏｎｌｅｖｅｌｓｏｆｆｉｂｒｏｓｉｓｍａｒｋｅｒｇｅｎｅｓα ＳＭＡ，ｃｏｌｌａｇｅｎⅠａｎｄｃｏｌｌａｇｅｎⅢ，ａｓｗｅｌｌａｓαａｎｄβｓｕｂｕｎｉｔｓｏｆＢＫＣａｃｈａｎｎｅｌｓｂｅｆｏｒｅａｎｄａｆｔｅｒｔｒｅａｔｍｅｎｔ．ＡｎｄｗｈｏｌｅｃｅｌｌｐａｔｃｈｃｌａｍｐｔｅｃｈｎｉｑｕｅｗａｓｕｓｅｄｔｏｄｅｔｅｃｔｔｈｅｃｕｒｒｅｎｔｃｈａｎｇｅｓｏｆＢＫＣａｃｈａｎｎｅｌｓｂｅｆｏｒｅａｎｄａｆｔｅｒＡｎｇⅡｔｒｅａｔｍｅｎｔ．Ｒｅｓｕｌｔｓ （１）ＡｆｔｅｒＡｎｇⅡｔｒｅａｔｍｅｎｔｏｆｈｕｍａｎａｔｒｉａｌｆｉｂｒｏｂｌａｓｔｓ，ｔｈｅｍＲＮＡａｎｄｐｒｏｔｅｉｎｅｘｐｒｅｓｓｉｏｎｌｅｖｅｌｓｏｆα ＳＭＡ，ｃｏｌｌａｇｅｎⅠａｎｄｃｏｌｌａｇｅｎⅢｉｎｃｒｅａｓｅｄ；（２）ＡｆｔｅｒＡｎｇⅡｔｒｅａｔｍｅｎｔ，ｔｈｅｍＲＮＡａｎｄｐｒｏｔｅｉｎｅｘｐｒｅｓｓｉｏｎｏｆＢＫＣａｃｈａｎｎｅｌαａｎｄβｓｕｂｕｎｉｔｓｄｅｃｒｅａｓｅｄ；（３）ＨｕｍａｎａｔｒｉａｌｆｉｂｒｏｂｌａｓｔｓｅｘｉｓｔｎｏｒｍａｌＢＫＣａｃｈａｎｎｅｌ，ｗｈｉｃｈａｒｅｖｏｌｔａｇｅｄｅｐｅｎｄｅｎｔ；（４）ＭａｃｒｏｃｕｒｒｅｎｔａｍｐｌｉｔｕｄｅｏｆＢＫＣａｃｈａｎｎｅｌｉｎｈｕｍａｎａｔｒｉａｌｆｉｂｒｏｂｌａｓｔｓｄｅｃｒｅａｓｅｄａｆｔｅｒＡｎｇⅡｔｒｅａｔｍｅｎｔ；（５）ＡｆｔｅｒｏｖｅｒｅｘｐｒｅｓｓｉｏｎｏｆＢＫＣａｃｈａｎｎｅｌαｓｕｂｕｎｉｔｏｎｈｕｍａｎａｔｒｉａｌｆｉｂｒｏｂｌａｓｔｓ，ｔｈｅｍＲＮＡａｎｄｐｒｏｔｅｉｎｅｘｐｒｅｓｓｉｏｎｌｅｖｅｌｓｏｆｆｉｂｒｏｓｉｓｍａｒｋｅｒα ＳＭＡ，ｃｏｌｌａｇｅｎⅠａｎｄｃｏｌｌａｇｅｎⅢｄｅｃｒｅａｓｅｄｓｉｇｎｉｆｉｃａｎｔｌｙ．Ｃｏｎｃｌｕｓｉｏｎ ＡｎｇⅡｍａｙｉｎｄｕｃｅｆｉｂｒｏｓｉｓｉｎｈｕｍａｎａｔｒｉａｌｆｉｂｒｏｂｌａｓｔｓｂｙｉｎｈｉｂｉｔｉｎｇｔｈｅｅｘｐｒｅｓｓｉｏｎａｎｄｆｕｎｃｔｉｏｎｏｆＢＫＣａｃｈａｎｎｅｌ，ａｎｄｆｉｎａｌｌｙｉｎｄｕｃｅａｔｒｉａｌｆｉｂｒｏｓｉｓ．【Ｋｅｙｗｏｒｄｓ】Ａｔｒｉａｌｆｉｂｒｏｓｉｓ；ＡｎｇｉｏｔｅｎｓｉｎⅡ；Ｈｕｍａｎａｔｒｉａｌｆｉｂｒｏｂｌａｓｔ；Ｌａｒｇｅｃｏｎｄｕｃｔａｎｃｅｃａｌｃｉｕｍ ａｃｔｉｖａｔｅｄｐｏｔａｓｓｉｕｍｃｈａｎｎｅｌ 心房颤动（房颤）是临床上最为常见的心律失常，有较高的发病率与死亡率，其发病机制复杂，其中以心房纤维化为代表的结构重构是重要始动因素［１］。
