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加州65提案（Proposition 65），即《安全饮用水和有毒物质强制法令》(Safe Drinking Water and Toxic Enforcement Act)，1986年11月于美国加州颁布施行，旨在保护加州公民及加州饮用水资源免受已知具有致癌、致出生缺陷或其他生殖毒性的化学物质的污染，同时，告知加利福尼亚公民有关暴露在他们所购买的物品、家里的或工作场所中的化学物质或释放进环境的化学物质的危害。
|加州65清单加州65要求政府至少每年公布一次“加州已知的可导致癌症或生殖毒性的化学品清单”，简称加州65清单，目前已经有近千种化学物质被公布。
企业如有使用该清单中的物质，则必须给予“清晰且合理”的警告，否则相关企业必须用科学的数据来证明其物质浓度在消费者正常使用过程中，其摄入量小于安全港数值（safe harbor level）。
最新加州65清单下载：加州65清单下载-2018.05.25最新加州65安全港数值下载：加州65安全港数值-2017.05.17|加州65的核心要求1、禁止污染饮用水源：生产、使用、释放本列表上的化学物质或另外从事含本列表上的化学物质的活动的企业，不容许将提案列明的危险化学物质排放到饮用水里；2、提供清晰且合理的警告标签：某一种化学物质被列入管控清单后，制造商和经销商须在12个月内对列明的化学物质提供警告，除非暴露含量特别低，不会造成重大风险；|加州65涉及的产品加州65针对珠宝、服装、箱包、运动垫具、玩具和儿童保育用品、陶瓷玻璃制品、铝制炊具、自行车及其配件、电气装置和电线电缆等产品都做了规定，几乎覆盖了所有的产品，并对危险品的暴露场景进行列明。
|加州65和解协议加州65本身并未对有害物质设定限值，只有安全港数值（safe harbor level），而应用此安全港数值，需要企业提供大量的支撑数据。
当个人或团体质疑某产品中的某些有害化学品安全水平并提出诉讼，最终达成和解协议或者裁决结果。
美国加州65标准（CP65）proposition 65加州第65号提案从颁布到现在已有20余年，一直秉持减少有毒化学物质的暴露的宗旨。
它允许加州居民通过一定的方式消除消费品和工业中的致癌物质和生殖毒性化学物质的行为。
自第65号提案制定以来，众多关于消费品中含有毒化学物质诉讼案在加州不断出现，从而引领整个美国一系列的限制标准的实施。
第65号提案，即《加州安全饮用水和有毒物执行法》，于1986 年11 月经加州居民投票，以压倒性的票数一致通过。
该提案由加州环境保护署(Cal/ EPA)辖下的环境健康危害评估机构(OEHHA) 执行。
提案规定，从事买卖的个体，其雇员人数达10个或10个以上的（另有豁免的除外），须在含已获知可致癌或生殖毒性的化学物质的产品上贴上清晰﹑合理的警告标签，以避免与人体接触，且不得将该等化学物质排放到饮用水中。
消费品警告可直接置于产品标签上，也可置于店面产品附近的显眼处（参照表1）。
表1 警告标签典型示例警告示例1 2WARNING: This product contains a chemical known to the State of California to cause cancer W ARNING: This product contains a chemical known to the State of California to cause birth defects or other reproductive harm第65号提案列出了大约800种已被加州当局确定为致癌性或生殖毒性的化学物清单。
该类化学物质清单包括大量自然产生的和人工合成的化学物质，包括用于杀虫剂﹑普通家用产品﹑食品﹑药物﹑染料或溶剂的添加剂或配料。
它们可用于制造业和建造业，也可以是化学过程的副产品，如机动车尾气。
所列化学物质包括烟草烟雾﹑金属（例如：铅﹑镉和镍）和有机化学物质（例如邻苯二甲酸盐：BBP﹑DBP﹑DEHP﹑DIDP﹑DnHP等，及多环芳香烃：苯并芘等）。
加州65号提案，即《1986年饮用水安全与毒性物质强制执行法》，于1986年11月颁发，其宗旨是保护美国加州居民及该州的饮用水水源，使水源不含已知可能导致癌症、出生缺陷或其他生殖发育危害的物质，并在出现该类物质时如实通知居民。
该法案被编纂列入加利福尼亚州健康和安全法典的第25249.5~25249.13章。
法案规定，从事买卖的个体，其雇员人数达10个或10个以上的（另有豁免的除外），须在含已获知可致癌或生殖毒性的化学物质的产品上加贴清晰、合理的警告标签，以避免与人体接触，且不得将这些化学物质排放到饮用水中。
警告信息可直接置于产品标签上，或采用在工作场所张贴标记、在租赁的建筑物内分发通知单、在报纸上登报通知等方式标示（如下图）。
法案要求加州政府出版具有致癌或生殖毒性的化学物质清单，清单每个季度进行更新。
从1987年首次出版以来，该清单中目前已包含约850种化学物质。
这些物质包括大量自然产生的和人工合成的化学物质，涉及用于杀虫剂、普通家用产品、食品、药物、染料或溶剂的添加剂或配料。
它们可用于制造业和建造业，也可以是化学过程的副产品，如机动车尾气。
所列化学物质包括烟草烟雾﹑金属（例如铅、镉和镍）和有机化学物质（例如邻苯二甲酸盐：BBP、DBP、DEHP、DINP、DIDP和DnOP等，以及多环芳香烃：苯并芘等）。
最新化学物质清单可通过“加州65提案列表”获取。
一旦某一种化学物质被列入清单后，制造商和经销商将须在一年内完成警告的执行，在20个月内终止化学物质排放至饮用水源头。
此日期过后，政府或个人执法者，包括代表公众利益的个人或组织，可对违反法规者提起诉讼。
加州65提案受控的产品范围包括：珠宝，玩具，电子设备，玻璃和陶瓷产品，纺织品，食品，药品，农用杀虫剂，染料，有机溶剂，建筑消耗品，汽车、香烟或天然气燃烧发出的化学物质，等等。
加州环境保护署（Cal/ EPA）辖下的环境健康危害评估办公室负责65提案的执行、更新和出版化学物质列表，以及开发物质等级数字指南（可致癌物质的NSRLs 和具生殖毒性化学物质的MADLs），企业可以通过以上文件，获知哪些物质需要警告标签，哪些化学物质被禁止释放到饮用水源中。
cp65管控物质标准
CP65 是美国加利福尼亚州的一项法规，全称为“加利福尼亚州
65 号提案”（California Proposition 65），该法规要求企业在产品中
限制使用某些有害物质，以保护公众健康和环境安全。
根据 CP65 法规，管控物质包括但不限于以下几类：
1. 重金属：如铅、镉、汞等。
2. 邻苯二甲酸酯类：如 DEHP、DBP、BBP、DINP、DIDP 等。
3. 多环芳烃类：如苯并[a]芘等。
4. 阻燃剂：如多溴联苯、多溴二苯醚等。
5. 其他有害物质：如甲醛、石棉等。
CP65 法规要求企业在产品中限制使用这些有害物质，并在产品上标注相关警示信息。
如果产品中含有管控物质，企业需要向加利福尼亚州政府报告，并遵守相关限制和要求。
需要注意的是，CP65 法规的具体要求和限制可能会根据不同的产品类型和用途而有所不同。
因此，在使用任何产品之前，建议查
阅相关的产品说明和警示信息，以确保产品符合CP65 法规的要求。
美国加州65检测标准美国加州65检测标准是美国加州政府给出的基准，用于对室内空气中在低污染水平下吸入有毒气体从而对健康造成影响的重金属、有毒有害物质和化学物质进行检测。
以下是美国加州65检测标准列表:一、重金属：1. 汞；2. 铅；3. 砷；4. 硒；5. 镉；6. 铬；7. 锡；8. 铜；9. 钒/钴；10. 铁；11. 锌；12. 铝。
二、致癌物质：1. 氯苯；2. 苯胺；4. 一次甲醛；5. 二甲苯；6. 丁醛；7. 3，3'，4，4'-四氯联苯；8. 異苯莫瑞；9. 多噁英；10. 甲醛；11. 苯乙烯；12. 氯乙烯；13. 乙酸乙酯；14. 环氧乙烷。
三、有毒有害芳香烃:1. 苯；2. 二甲苯；3. 乙醇；4. 游离氯；5. 溴氯化合物；6. 硫化氢；7. 氨；8. 戊烷；9. 三氯乙烷；10. 甲苯；12. 丁烷；13. 乙烯；14. 妥玛拉唑；15. 吡唑酮；16. 对甲醛。
四、化学物质:1. 三氯甲烷；2. 多氯联苯；3. 硼氮（Hg）；4. 叠氮苯（TDB）；5. 硝基二甲苯（NDB）；6. 二氯甲烷；7. 硫醚；8. 苯胺；9. 甲醇；10. 氯乙酸；11. 氯丙酮；12. 氯亚甲基溴；13. 二甲醚；14. 1，4-二氯苯；15. 低氯乙烯；16. 异丙基苯醚；18. 氯乙酸乙酯；19. 叔丁醇醚；20. 氯甲烷；21. 痕量微量元素，如钯、钼、镍、钨、铬、碘和汞等。
美国加州65检测标准是一套严格的检测标准，旨在确保室内空气质量，减少有毒化学物质对人类健康的影响。
美国加州政府尤其重视重金属的检测，因为这些重金属的污染会通过饮用水和摄入食物等方式对人类健康造成危害。
此外，致癌物质、有毒有害芳香烃和一些化学物质也会对健康造成不良影响，所以也进行仔细检查。
美国加州政府还采用了各种技术措施，如室内空气检测网络、更好的室内装修材料等，来防止有毒的物质进入室内空气，以确保居民的室内空气质量和健康。
美国加州65法案(CP65)Contentsl CP65号提案（安全饮用水和有毒物质强制法令）l CP65提案的核心要求l化学品如何添加到加州65号提案中l CP65管控物质l企业如何应对l警告条款更新l警告标签要求l2020年加州65处罚案例汇总l加州65法案对化学品的某些结案案例要点l CP65和RoHS 2.0CP65号提案（安全饮用水和有毒物质强制法令）颁布实施时间：后被编纂列入加利福尼亚州健康和安全法典的25249.5-25249.13章。
涉及产品：珠宝、玩具、电气装置、玻璃陶瓷材料、服装、饰物、药、农药、染料、化妆品、礼品、制造或施工用品、化学过程的副产品如汽车尾气、烟雾、天然气燃烧等，几乎覆盖了所有的产品，并对危险品的暴露场景进行列明。
宗旨：保护美国加州居民及该州的饮用水水源，使水源不含已知可能导致癌症、出生缺陷或其他生殖发育危害的物质，并在出现该类物质时如实通知居民。
CP65提案的核心要求√ 不容许将提案列明的危险物质排放到饮用水里。
√提供清晰且合理的警告豁免：雇员少于10人的企业或政府机构可解除到的化学物质含量非常低，不至于产生重大致癌或致畸或其他生产危害（难以证明）某一种化学物质归入了第65号提案清单之列，制造商和经销商将须在一年内完成警告的执行，在20个月内终止化学物质排放至饮用水源头。
此日期过后，政府或个人执法者，包括代表公众利益的个人或组织，可对未达标者采取法律行为。
化学品如何添加到加州65号提案中加利福尼亚州必须至少每年更新一次有害化学品清单，有四种情况下化学物质可以被添加到列表中。
1.劳动法典（LC）世界卫生组织国际癌症研究机构确定的化学物质是人类或动物癌症的原因。
2.州的合格专家（SQE）如果两个独立的科学和健康专家委员会发现该化学物质会导致癌症，先天缺陷或其他生殖危害，则可添加化学品。
致癌物质鉴定委员会（CIC）和发育和生殖毒物鉴定委员会（DARTIC）每年举行一次会议，以评估属于第65号提案的化学品。
危险化学品目录2018版危险化学品目录（2018版）易燃固体：类别1、类别2。
自反应物质和混合物：A型、B型、C型、D型、E型。
自燃液体：类别1。
自燃固体：类别1。
自热物质和混合物：类别1、类别2。
遇水放出易燃气体的物质和混合物：类别1、类别2、类别3。
氧化性液体：类别1、类别2、类别3。
氧化性固体：类别1、类别2、类别3。
有机过氧化物：A型、B型、C型、D型、E型、F型。
金属腐蚀物：类别1。
2．健康危害急性毒性：类别1、类别2、类别3。
皮肤腐蚀/刺激：类别1A、类别1B、类别1C、类别2。
严重眼损伤/眼刺激：类别1、类别2A、类别2B。
呼吸道或皮肤致敏：呼吸道致敏物1A、呼吸道致敏物1B、皮肤致敏物1A、皮肤致敏物1B。
生殖细胞致突变性：类别1A、类别1B、类别2。
致癌性：类别1A、类别1B、类别2。
生殖毒性：类别1A、类别1B、类别2、附加类别。
特异性靶器官毒性-一次接触：类别1、类别2、类别3。
特异性靶器官毒性-反复接触：类别1、类别2。
吸入危害：类别1。
3．环境危害危害水生环境-急性危害：类别1、类别2；危害水生环境-长期危害：类别1、类别2、类别3。
危害臭氧层：类别1。
二、剧毒化学品的定义和判定界限定义：具有剧烈急性毒性危害的化学品，包括人工合成的化学品及其混合物和天然毒素，还包括具有急性毒性易造成公共安全危害的化学品。
剧烈急性毒性判定界限：急性毒性类别1，即满足下列条件之一：大鼠实验，经口LD50≤5mg/kg，经皮LD50≤50mg/kg，吸入（4h）LC50≤100ml/m3（气体）或0.5mg/L（蒸气）或0.05mg/L（尘、雾）。
经皮LD50的实验数据，也可使用兔实验数据。
三、《危险化学品目录》各栏目的含义（一）“序号”是指《危险化学品目录》中化学品的顺序号。
（二）“品名”是指根据《化学命名原则》（1980）确定的名称。
（三）“别名”是指除“品名”以外的其他名称，包括通用名、俗名等。
加州65提案物质管控清单-概述说明以及解释1.引言1.1 概述加州65提案，全名为加州65号公告，是由加州议会提出的一项法案，旨在对危险化学物质进行控制和管理。
该提案制定了一个物质管控清单，列出了一系列被认为有潜在危害的物质，要求企业在产品中使用这些物质时进行披露和警示。
这个清单不仅包括化学品，还涉及到了化妆品、食品和家庭用品等不同领域的产品。
加州65提案的目的是保护公众和环境的健康与安全，增加对潜在危害物质的认识和警惕。
通过公开披露和警示，消费者可以更好地了解产品中存在的潜在风险，并自主选择是否购买或使用。
该提案的实施对企业产生了重大影响，要求企业进行复杂的风险评估和物质管理，以确保产品的安全性和合规性。
同时，这项法案也促使了企业加强研发和创新，寻找替代品和更安全的生产工艺，以适应市场的需求和法规的要求。
经过多年的实施和不断调整，加州65提案已经成为全国范围内关于危险化学物质管理的重要准则。
许多其他州和国家也参考加州65提案的物质管控清单，加强对潜在危险物质的监管和管理。
本文将深入探讨加州65提案的内容和重要性，分析其对社会和环境的影响，以及对企业和消费者的意义。
通过对加州65提案的全面了解，我们能够更好地理解物质管控的重要性，促进可持续发展和环境保护。
1.2文章结构文章结构部分的内容可以参考以下写法：1.2 文章结构本文将按照以下结构进行讨论：第二章将介绍加州65提案的背景和内容。
首先，我们将简要回顾提案的起因和背景，以了解为什么有必要进行物质管控。
接下来，我们将详细探讨加州65提案的具体内容，包括提案中列出的物质管控清单及其所涵盖的范围。
第三章将探讨物质管控清单的重要性。
我们将分析为什么对这些物质进行管控是至关重要的，以及物质管控对于保护人类和环境健康的积极意义。
我们还将讨论这些清单对于企业和消费者的影响，并探讨可能的挑战和解决方案。
最后，第四章将从整体上总结加州65提案的影响并探讨其在社会和环境方面的意义。
STATE OF CALIFORNIAENVIRONMENTAL PROTECTION AGENCYOFFICE OF ENVIRONMENTAL HEALTH HAZARD ASSESSMENTSAFE DRINKING WATER AND TOXIC ENFORCEMENT ACT OF 1986 CHEMICALS KNOWN TO THE STATE TO CAUSE CANCER OR REPRODUCTIVE TOXICITYFEBRUARY 8, 2013The Safe Drinking Water and Toxic Enforcement Act of 1986 requires that the Governor revise and republish at least once per year the list of chemicals known to the State to cause cancer or reproductive toxicity. The identification number indicated in the following list is the Chemical Abstracts Service (CAS) Registry Number. No CAS number is given when several substances are presented as a single listing. The date refers to the initial appearance of the chemical on the list. For easy reference, chemicals which are shown underlined are newly added. Chemicals or endpoints shown in strikeout were placed on the Proposition 65 list on the date noted, and have subsequently been removed.Chemical Type of Toxicity CAS No. Date ListedA-alpha-C (2-Amino-9H-pyrido cancer 26148-68-5 January 1, 1990[2,3-b]indole)Acetaldehyde cancer 75-07-0 April 1, 1988 Acetamide cancer 60-35-5 January 1, 1990 Acetazolamide developmental 59-66-5 August 20, 1999 Acetochlor cancer 34256-82-1 January 1, 1989 Acetohydroxamic acid developmental 546-88-3 April 1, 19902-Acetylaminofluorene cancer 53-96-3 July 1, 1987 Acifluorfen sodium cancer 62476-59-9 January 1, 1990 Acrylamide cancer 79-06-1 January 1, 1990 Acrylamide developmental, male 79-06-1 February 25, 2011 Acrylonitrile cancer 107-13-1 July 1, 1987 Actinomycin D cancer 50-76-0 October 1, 1989developmental October 1, 1992 AF-2;[2-(2-furyl)-3-(5-nitro-2-furyl)] cancer 3688-53-7 July 1, 1987acrylamideAflatoxins cancer --- January 1, 1988 Alachlor cancer 15972-60-8 January 1, 1989 Alcoholic beverages, when cancer --- July 1, 1988associated with alcohol abuseAldrin cancer 309-00-2 July 1, 1988All-trans retinoic acid developmental 302-79-4 January 1, 1989 Allyl chloride cancer107-05-1January 1, 1990 Delisted October 29, 1999Alprazolam developmental 28981-97-7 July 1, 1990 Altretamine developmental, male 645-05-6 August 20, 1999 Amantadine hydrochloride developmental 665-66-7 February 27, 2001 Amikacin sulfate developmental 39831-55-5 July 1, 19902-Aminoanthraquinone cancer 117-79-3 October 1, 1989p-Aminoazobenzene cancer 60-09-3 January 1, 1990o-Aminoazotoluene cancer 97-56-3 July 1, 19874-Aminobiphenyl (4-amino- cancer 92-67-1 February 27, 1987 diphenyl)1-Amino-2,4-dibromo- cancer 81-49-2 August 26, 1997anthraquinone3-Amino-9-ethylcarbazole cancer 6109-97-3 July 1, 1989hydrochloride2-Aminofluorene cancer 153-78-6 January 29, 1999 Aminoglutethimide developmental 125-84-8 July 1, 1990 Aminoglycosides developmental --- October 1, 19921-Amino-2-methylanthraquinone cancer 82-28-0 October 1, 19892-Amino-5-(5-nitro-2-furyl)-1,3,4- cancer 712-68-5 July 1, 1987thiadiazole4-Amino-2-nitrophenol cancer 119-34-6 January 29, 1999 Aminopterin developmental, female 54-62-6 July 1, 1987 Amiodarone hydrochloride developmental, female, 19774-82-4 August 26, 1997maleAmitraz developmental 33089-61-1 March 30, 1999 Amitrole cancer 61-82-5 July 1, 1987 Amoxapine developmental 14028-44-5 May 15, 1998 Amsacrine cancer 51264-14-3 August 7, 2009tert-Amyl methyl ether developmental 994-05-8 December 18, 2009 Anabolic steroids female, male --- April 1, 1990 Analgesic mixtures containing cancer --- February 27, 1987 phenacetinAndrostenedione cancer 27208-37-3 May 3, 2011 Angiotensin converting enzyme developmental --- October 1, 1992(ACE) inhibitorsAniline cancer 62-53-3 January 1, 1990 Aniline hydrochloride cancer 142-04-1 May 15, 1998o-Anisidine cancer 90-04-0 July 1, 1987o-Anisidine hydrochloride cancer 134-29-2 July 1, 1987 Anisindione developmental 117-37-3 October 1, 1992 Anthraquinone cancer 84-65-1 September 28, 2007 Antimony oxide (Antimony trioxide) cancer 1309-64-4 October 1, 1990 Aramite cancer 140-57-8 July 1, 1987Areca nut cancer --- February 3, 2006 Aristolochic acids cancer --- July 9, 2004 Arsenic (inorganic arsenic cancer -- February 27, 1987 compounds)Arsenic (inorganic oxides) developmental --- May 1, 1997 Asbestos cancer 1332-21-4 February 27, 1987 Aspirin (NOTE: It is especially developmental, female 50-78-2 July 1, 1990important not to use aspirinduring the last three months ofpregnancy, unless specificallydirected to do so by a physicianbecause it may cause problemsin the unborn child orcomplications during delivery.)Atenolol developmental 29122-68-7 August 26, 1997 Auramine cancer 492-80-8 July 1, 1987 Auranofin developmental 34031-32-8 January 29, 1999Avermectin B1 (Abamectin) developmental 71751-41-2 December 3, 2010 Azacitidine cancer 320-67-2 January 1, 1992 Azaserine cancer 115-02-6 July 1, 1987 Azathioprine cancer 446-86-6 February 27, 1987 Azathioprine developmental 446-86-6 September 1, 1996 Azobenzene cancer 103-33-3 January 1, 1990Barbiturates developmental --- October 1, 1992 Beclomethasone dipropionate developmental 5534-09-8 May 15, 1998 Benomyl developmental, male 17804-35-2 July 1, 1991 Benthiavalicarb-isopropyl cancer 177406-68-7 July 1, 2008Benz[a]anthracene cancer 56-55-3 July 1, 1987 Benzene cancer 71-43-2 February 27, 1987 Benzene developmental, male 71-43-2 December 26, 1997 Benzidine [and its salts] cancer 92-87-5 February 27, 1987 Benzidine-based dyes cancer --- October 1, 1992 Benzodiazepines developmental --- October 1, 1992 Benzo[b]fluoranthene cancer 205-99-2 July 1, 1987 Benzo[j]fluoranthene cancer 205-82-3 July 1, 1987 Benzo[k]fluoranthene cancer 207-08-9 July 1, 1987 Benzofuran cancer 271-89-6 October 1, 1990 Benzophenone cancer 119-61-9 June 22, 2012 Benzo[a]pyrene cancer 50-32-8 July 1, 1987 Benzotrichloride cancer 98-07-7 July 1, 1987 Benzphetamine hydrochloride developmental 5411-22-3 April 1, 1990 Benzyl chloride cancer 100-44-7 January 1, 1990 Benzyl violet 4B cancer 1694-09-3 July 1, 1987 Beryllium and beryllium compounds cancer --- October 1, 1987 Betel quid with tobacco cancer --- January 1, 1990 Betel quid without tobacco cancer --- February 3, 2006 2,2-Bis(bromomethyl)-1,3- cancer 3296-90-0 May 1, 1996propanediolBis(2-chloroethyl)ether cancer 111-44-4 April 1, 1988N,N-Bis(2-chloroethyl)-2- cancer 494-03-1 February 27, 1987 naphthylamine (Chlornapazine)Bischloroethyl nitrosourea (BCNU) cancer 154-93-8 July 1, 1987(Carmustine)Bischloroethyl nitrosourea (BCNU) developmental 154-93-8 July 1, 1990(Carmustine)Bis(chloromethyl)ether cancer 542-88-1 February 27, 1987 Bis(2-chloro-1-methylethyl)ether, cancer --- October 29, 1999 technical gradeBitumens, extracts of steam-refined cancer --- January 1, 1990and air refinedBracken fern cancer --- January 1, 1990 Bromacil lithium salt developmental 53404-19-6 May 18, 1999 Bromacil lithium salt male 53404-19-6 January 17, 2003 Bromate cancer 15541-45-4 May 31, 2002 Bromochloroacetic acid cancer 5589-96-8 April 6, 2010 Bromodichloromethane cancer 75-27-4 January 1, 1990 Bromoethane cancer 74-96-4 December 22, 2000 Bromoform cancer 75-25-2 April 1, 19911-Bromopropane (1-BP) developmental, female, 106-94-5 December 7, 2004male2-Bromopropane (2-BP) female, male 75-26-3 May 31, 2005 Bromoxynildevelopmental 1689-84-5 October 1, 1990 Bromoxynil octanoate developmental 1689-99-2 May 18, 1999 Butabarbital sodium developmental 143-81-7 October 1, 1992 1,3-Butadiene cancer106-99-0 April 1, 1988 1,3-Butadiene developmental, female, 106-99-0 April 16, 2004male1,4-Butanediol dimethanesulfonate cancer 55-98-1 February 27, 1987 (Busulfan)1,4-Butanediol dimethanesulfonate developmental 55-98-1 January 1, 1989 (Busulfan)Butylated hydroxyanisole cancer25013-16-5 January 1, 1990 Butyl benzyl phthalate (BBP) developmental 85-68-7 December 2, 2005 n-Butyl glycidyl ether male 2426-08-6 August 7, 2009 beta-Butyrolactone cancer 3068-88-0 July 1, 1987Cacodylic acid cancer75-60-5 May 1, 1996 Cadmiumdevelopmental, male --- May 1, 1997 Cadmium and cadmium cancer --- October 1, 1987 compoundsCaffeic acid cancer 331-39-5 October 1, 1994 Captafol cancer 2425-06-1 October 1, 1988 Captancancer133-06-2 January 1, 1990 Carbamazepine developmental 298-46-4 January 29, 1999 Carbaryl cancer63-25-2 February 5, 2010 Carbaryl developmental, male 63-25-2 August 7, 2009 Carbazolecancer 86-74-8 May 1, 1996Carbon black (airborne, unbound cancer 1333-86-4 February 21, 2003 particles of respirable size)Carbon disulfide developmental, female, 75-15-0 July 1, 1989maleCarbon monoxide developmental 630-08-0 July 1, 1989 Carbon tetrachloride cancer 56-23-5 October 1, 1987 Carbon-black extracts cancer---January 1, 1990 Carboplatindevelopmental 41575-94-4 July 1, 1990N-Carboxymethyl-N-nitrosourea cancer 60391-92-6 January 25, 2002 Catecholcancer 120-80-9 July 15, 2003 Ceramic fibers (airborne particles cancer --- July 1, 1990 of respirable size)Certain combined chemotherapy cancer --- February 27, 1987 for lymphomasChenodiol developmental 474-25-9 April 1, 1990Chlorambucil cancer305-03-3 February 27, 1987 Chlorambucil developmental 305-03-3 January 1, 1989 ChloramphenicolDelisted January 4, 2013 cancer 56-75-7 October 1, 1989 Chlorcyclizine hydrochloride developmental 1620-21-9 July 1, 1987 Chlordanecancer57-74-9July 1, 1988Chlordecone (Kepone) cancer143-50-0 January 1, 1988 Chlordecone (Kepone) developmental 143-50-0 January 1, 1989 Chlordiazepoxidedevelopmental 58-25-3 January 1, 1992 Chlordiazepoxide hydrochloride developmental 438-41-5 January 1, 1992 Chlordimeform cancer 6164-98-3 January 1, 1989 Chlorendic acidcancer 115-28-6 July 1, 1989 Chlorinated paraffins (Average cancer 108171-26-2 July 1, 1989 chain length, C12; approximately 60 percent chlorine by weight)p -Chloroanilinecancer 106-47-8 October 1, 1994 p -Chloroaniline hydrochloride cancer 20265-96-7 May 15, 1998 Chlorodibromomethane cancer 124-48-1 January 1, 1990 Delisted October 29, 1999Chloroethane (Ethyl chloride) cancer 75-00-3 July 1, 1990 1-(2-Chloroethyl)-3-cyclohexyl- cancer 13010-47-4 January 1, 1988 1-nitrosourea (CCNU) (Lomustine)1-(2-Chloroethyl)-3-cyclohexyl- developmental 13010-47-4 July 1, 1990 1-nitrosourea (CCNU) Lomustine)1-(2-Chloroethyl)-3-(4-methyl- cancer 13909-09-6 October 1, 1988 cyclohexyl) -1-nitrosourea (Methyl-CCNU)Chloroform cancer67-66-3 October 1, 1987 Chloroformdevelopmental 67-66-3 August 7, 2009 Chloromethyl methyl ether cancer 107-30-2 February 27, 1987 (technical grade)3-Chloro-2-methylpropene cancer 563-47-3 July 1, 19891-Chloro-4-nitrobenzenecancer 100-00-5 October 29, 1999 4-Chloro-o -phenylenediamine cancer 95-83-0 January 1, 1988 Chloroprenecancer 126-99-8 June 2, 2000 2-Chloropropionic acid male 598-78-7 August 7, 2009 Chlorothalonilcancer 1897-45-6 January 1, 1989 p -Chloro-o -toluidinecancer 95-69-2 January 1, 1990 p-Chloro-o -toluidine, strong acid cancer --- May 15, 1998 salts of5-Chloro-o -toluidine and cancer --- October 24, 1997 its strong acid saltsChlorotrianisene cancer 569-57-3 September 1, 1996 Chlorozotocin cancer54749-90-5 January 1, 1992 Chlorsulfuron developmental, female, 64902-72-3 May 14, 1999maleChromium (hexavalent compounds) cancer--- February 27, 1987 Chromium (hexavalent compounds) developmental, female, male ---December 19, 2008 Chrysenecancer 218-01-9 January 1, 1990 C.I. Acid Red 114 cancer 6459-94-5 July 1, 1992 C.I. Basic Red 9 cancer 569-61-9 July 1, 1989 monohydrochlorideC.I. Direct Blue 15 cancer 2429-74-5 August 26, 1997 C.I. Direct Blue 218 cancer 28407-37-6 August 26, 1997 C.I. Disperse Yellow 3 cancer 2832-40-8 February 8, 2013 C.I. Solvent Yellow 14cancer 842-07-9 May 15, 1998 Ciclosporin (Cyclosporin A; cancer 59865-13-3 January 1, 1992 Cyclosporine)79217-60-0Cidofovir cancer, developmental, 113852-37-2 January 29, 1999female, maleCinnamyl anthranilate cancer 87-29-6 July 1, 1989 Cisplatin cancer 15663-27-1 October 1, 1988 Citrus Red No. 2 cancer 6358-53-8 October 1, 1989 Cladribine developmental 4291-63-8 September 1, 1996 Clarithromycin developmental 81103-11-9 May 1, 1997 Clobetasol propionate developmental, female 25122-46-7 May 15, 1998 Clofibrate cancer 637-07-0 September 1, 1996 Clomiphene citrate developmental 50-41-9 April 1, 1990 Clorazepate dipotassium developmental 57109-90-7 October 1, 1992 Cobalt metal powder cancer 7440-48-4 July 1, 1992 Cobalt [II] oxide cancer 1307-96-6 July 1, 1992 Cobalt sulfate cancer 10124-43-3 May 20, 2005 Cobalt sulfate heptahydrate cancer 10026-24-1 June 2, 2000 Cocaine developmental, female 50-36-2 July 1, 1989 Coconut oil diethanolamine cancer --- June 22, 2012condensate (cocamidediethanolamine)Codeine phosphate developmental 52-28-8 May 15, 1998 Coke oven emissions cancer --- February 27, 1987 Colchicine developmental, male 64-86-8 October 1, 1992 Conjugated estrogens cancer --- February 27, 1987 Conjugated estrogens developmental --- April 1, 1990 Creosotes cancer --- October 1, 1988p-Cresidine cancer 120-71-8 January 1, 1988 Cumene cancer 98-82-8 April 6, 2010 Cupferron cancer 135-20-6 January 1, 1988 Cyanazine developmental 21725-46-2 April 1, 1990 Cycasin cancer 14901-08-7 January 1, 1988 Cycloate developmental 1134-23-2 March 19, 1999 Cyclohexanol Delisted male 108-93-0 November 6, 1998 January 25, 2002Cycloheximide developmental 66-81-9 January 1, 1989 Cyclopenta[cd]pyrene cancer 27208-37-3 April 29, 2011 Cyclophosphamide (anhydrous) cancer 50-18-0 February 27, 1987 Cyclophosphamide (anhydrous) developmental, female, 50-18-0 January 1, 1989maleCyclophosphamide (hydrated) cancer 6055-19-2 February 27, 1987 Cyclophosphamide (hydrated) developmental, female, 6055-19-2 January 1, 1989maleCyhexatin developmental 13121-70-5 January 1, 1989 Cytarabine developmental 147-94-4 January 1, 1989 Cytembena cancer 21739-91-3 May 15, 1998D&C Orange No. 17 cancer 3468-63-1 July 1, 1990D&C Red No. 8 cancer 2092-56-0 October 1, 1990D&C Red No. 9 cancer 5160-02-1 July 1, 1990D&C Red No. 19 cancer 81-88-9 July 1, 1990 Dacarbazine cancer 4342-03-4 January 1, 1988 Dacarbazine developmental 4342-03-4 January 29, 1999 Daminozide cancer 1596-84-5 January 1, 1990Danazol developmental 17230-88-5 April 1, 1990 Dantron (Chrysazin; 1,8- cancer 117-10-2 January 1, 1992 Dihydroxyanthraquinone)Daunomycin cancer 20830-81-3 January 1, 1988 Daunorubicin hydrochloride developmental 23541-50-6 July 1, 19902,4-D butyric acid developmental, male 94-82-6 June 18, 1999 DDD (Dichlorodiphenyl- cancer 72-54-8 January 1, 1989 dichloroethane)DDE (Dichlorodi- cancer 72-55-9 January 1, 1989 phenyldichloroethylene)DDT (Dichlorodi- cancer 50-29-3 October 1 , 1987 phenyltrichloroethane)o,p’-DDT developmental, female, 789-02-6 May 15, 1998malep,p’-DDT developmental, female, 50-29-3 May 15, 1998maleDDVP (Dichlorvos) cancer 62-73-7 January 1, 1989 Demeclocycline hydrochloride developmental 64-73-3 January 1, 1992 (internal use)2,4-DP (dichloroprop) developmental 120-36-5 April 27, 1999 Delisted January 25, 2002N,N’-Diacetylbenzidine cancer 613-35-4 October 1, 1989 2,4-Diaminoanisole cancer 615-05-4 October 1, 1990 2,4-Diaminoanisole sulfate cancer 39156-41-7 January 1, 1988 4,4’-Diaminodiphenyl ether cancer 101-80-4 January 1, 1988 (4,4’-Oxydianiline)2,4-Diaminotoluene cancer 95-80-7 January 1, 1988 Diaminotoluene (mixed) cancer --- January 1, 1990 Diazepam developmental 439-14-5 January 1, 1992 Diazoaminobenzene cancer 136-35-6 May 20, 2005 Diazoxide developmental 364-98-7 February 27, 2001 Dibenz[a,h]acridine cancer 226-36-8 January 1, 1988 Dibenz[a,j]acridine cancer 224-42-0 January 1, 1988 Dibenz[a,h]anthracene cancer 53-70-3 January 1, 1988 7H-Dibenzo[c,g]carbazole cancer 194-59-2 January 1, 1988 Dibenzo[a,e]pyrene cancer 192-65-4 January 1, 1988 Dibenzo[a,h]pyrene cancer 189-64-0 January 1, 1988 Dibenzo[a,i]pyrene cancer 189-55-9 January 1, 1988 Dibenzo[a,l]pyrene cancer 191-30-0 January 1, 1988 Dibromoacetic acid cancer 631-64-1 June 17, 2008 Dibromoacetonitrile cancer 3252-43-5 May 3, 20111,2-Dibromo-3-chloropropane cancer 96-12-8 July 1, 1987(DBCP)1,2-Dibromo-3-chloropropane male 96-12-8 February 27, 1987 (DBCP)2,3-Dibromo-1-propanol cancer 96-13-9 October 1, 1994 Dichloroacetic acid cancer 79-43-6 May 1, 1996 Dichloroacetic acid male 79-43-6 August 7, 2009p-Dichlorobenzene cancer 106-46-7 January 1, 1989 3,3’-Dichlorobenzidine cancer 91-94-1 October 1, 1987 3,3’-Dichlorobenzidine cancer 612-83-9 May 15, 1998dihydrochloride1,1-Dichloro-2,2-bis(p- developmental, male 72-55-9 March 30, 2010chlorophenyl)ethylene (DDE)1,4-Dichloro-2-butene cancer 764-41-0 January 1, 1990 3,3’-Dichloro-4,4’-diaminodiphenyl cancer 28434-86-8 January 1, 1988 ether1,1-Dichloroethane cancer 75-34-3 January 1, 1990 Dichloromethane (Methylene cancer 75-09-2 April 1, 1988chloride)Dichlorophene developmental 97-23-4 April 27, 19991,2-Dichloropropane cancer 78-87-5 January 1, 1990 1,3-Dichloro-2-propanol (1,3-DCP) cancer 96-23-1 October 8, 2010 1,3-Dichloropropene cancer 542-75-6 January 1, 1989 Dichlorphenamide developmental 120-97-8 February 27, 2001 Diclofop-methyl cancer 51338-27-3 April 6, 2010 Diclofop methyl developmental 51338-27-3 March 5, 1999 Dicumarol developmental 66-76-2 October 1, 1992 Dieldrin cancer 60-57-1 July 1, 1988 Dienestrol Delisted January 4, 2013 cancer 84-17-3 January 1, 1990 Diepoxybutane cancer 1464-53-5 January 1, 1988 Diesel engine exhaust cancer --- October 1, 1990 Diethanolamine cancer 111-42-2 June 22, 2012Di(2-ethylhexyl)phthalate (DEHP) cancer 117-81-7 January 1, 1988 Di(2-ethylhexyl)phthalate (DEHP) developmental, male 117-81-7 October 24, 2003 1,2-Diethylhydrazine cancer 1615-80-1 January 1, 1988 Diethylstilbestrol (DES) cancer 56-53-1 February 27, 1987 Diethylstilbestrol (DES) developmental 56-53-1 July 1, 1987 Diethyl sulfate cancer 64-67-5 January 1, 1988 Diflunisal developmental, female 22494-42-4 January 29, 1999 Diglycidyl ether male 2238-07-5 August 7, 2009 Diglycidyl resorcinol ether (DGRE) cancer 101-90-6 July 1, 1989 Dihydroergotamine mesylate developmental 6190-39-2 May 1, 1997 Dihydrosafrole cancer 94-58-6 January 1, 1988 Di-isodecyl phthalate (DIDP) developmental 68515-49-1/ April 20, 200726761-40-0Diisopropyl sulfate cancer 2973-10-6 April 1, 1993 Diltiazem hydrochloride developmental 33286-22-5 February 27, 2001 3,3’-Dimethoxybenzidine cancer 119-90-4 January 1, 1988 (o-Dianisidine)3,3’-Dimethoxybenzidine cancer 20325-40-0 October 1, 1990 dihydrochloride(o-Dianisidine dihydrochloride)3,3’-Dimethoxybenzidine-based cancer --- June 11, 2004dyes metabolized to 3,3’-dimethoxybenzidineN, N-Dimethylacetamide developmental 127-19-5 May 21, 20104-Dimethylaminoazobenzene cancer 60-11-7 January 1, 1988 trans-2-[(Dimethylamino)methyl-cancer 55738-54-0 January 1, 1988 imino]-5-[2-(5-nitro-2-furyl)vinyl]-1,3,4-oxadiazole7,12-Dimethylbenz(a)anthracene cancer 57-97-6 January 1, 1990 3,3’-Dimethylbenzidine cancer 119-93-7 January 1, 1988 (ortho-Tolidine)3,3’-Dimethylbenzidine-based cancer --- June 11, 2004dyes metabolized to 3,3’-dimethylbenzidine3,3’-Dimethylbenzidine cancer 612-82-8 April 1, 1992dihydrochlorideDimethylcarbamoyl chloride cancer 79-44-7 January 1, 1988 1,1-Dimethylhydrazine (UDMH) cancer 57-14-7 October 1, 1989 1,2-Dimethylhydrazine cancer 540-73-8 January 1, 1988 2,6-Dimethyl-N-nitrosomorpholine cancer 1456-28-6 February 8, 2013 Dimethyl sulfate cancer 77-78-1 January 1, 1988 Dimethylvinylchloride cancer 513-37-1 July 1, 1989Di-n-butyl phthalate (DBP) developmental, female, 84-74-2 December 2, 2005maleDi-n-hexyl phthalate (DnHP) female, male 84-75-3 December 2, 2005 m-Dinitrobenzene male 99-65-0 July 1, 1990o-Dinitrobenzene male 528-29-0 July 1, 1990p-Dinitrobenzene male 100-25-4 July 1, 19903,7-Dinitrofluoranthene cancer 105735-71-5 August 26, 1997 3,9-Dinitrofluoranthene cancer 22506-53-2 August 26, 1997 1,3-Dinitropyrene cancer 75321-20-9 November 2, 2012 1,6-Dinitropyrene cancer 42397-64-8 October 1, 1990 1,8-Dinitropyrene cancer 42397-65-9 October 1, 1990 Dinitrotoluene (technical grade) female, male --- August 20, 1999 Dinitrotoluene mixture, 2,4-/2,6- cancer --- May 1, 19962,4-Dinitrotoluene cancer 121-14-2 July 1, 19882,4-Dinitrotoluene male 121-14-2 August 20, 1999 2,6-Dinitrotoluene cancer 606-20-2 July 1, 19952,6-Dinitrotoluene male 606-20-2 August 20, 1999 Dinocap developmental 39300-45-3 April 1, 1990 Dinoseb developmental, male 88-85-7 January 1, 1989 Di-n-propyl isocinchomeronate cancer 136-45-8 May 1, 1996(MGK Repellent 326)1,4-Dioxane cancer 123-91-1 January 1, 1988 Diphenylhydantoin (Phenytoin) cancer 57-41-0 January 1, 1988 Diphenylhydantoin (Phenytoin) developmental 57-41-0 July 1, 1987 Diphenylhydantoin (Phenytoin), cancer 630-93-3 January 1, 1988 sodium saltDirect Black 38 (technical grade) cancer 1937-37-7 January 1, 1988 Direct Blue 6 (technical grade) cancer 2602-46-2 January 1, 1988 Direct Brown 95 (technical grade) cancer 16071-86-6 October 1, 1988 Disodium cyanodithioimido- developmental 138-93-2 March 30, 1999carbonateDisperse Blue 1 cancer 2475-45-8 October 1, 1990 Diuron cancer 330-54-1 May 31, 2002 Doxorubicin hydrochloride cancer 25316-40-9 July 1, 1987(Adriamycin)Doxorubicin hydrochloride developmental, male 25316-40-9 January 29, 1999 (Adriamycin)Doxycycline (internal use) developmental 564-25-0 July 1, 1990 Doxycycline calcium (internal use) developmental 94088-85-4 January 1, 1992 Doxycycline hyclate (internal use) developmental 24390-14-5 October 1, 1991 Doxycycline monohydrate developmental 17086-28-1 October 1, 1991(internal use)Endrin developmental 72-20-8 May 15, 1998 Environmental tobacco smoke developmental --- June 9, 2006(ETS)Epichlorohydrin cancer 106-89-8 October 1, 1987 Epichlorohydrin male 106-89-8 September 1, 1996 Epoxiconazole cancer 135319-73-2 April 15, 2011 Ergotamine tartrate developmental 379-79-3 April 1, 1990 Erionite cancer 12510-42-8/ October 1, 198866733-21-9Estradiol 17B cancer 50-28-2 January 1, 1988 Estragole cancer 140-67-0 October 29, 1999 Estrogens, steroidal cancer --- August 19, 2005 Estrogen-progestogen (combined) cancer --- November 4, 2011 as menopausal therapyEstrone cancer 53-16-7 January 1, 1988 Estropipate cancer, developmental 7280-37-7 August 26, 1997 Ethanol in alcoholic beverages cancer --- April 29, 2011 Ethinylestradiol cancer 57-63-6 January 1, 1988 Ethionamide developmental 536-33-4 August 26, 1997 Ethoprop cancer 13194-48-4 February 27, 2001 Ethyl acrylate cancer 140-88-5 July 1, 1989Ethyl alcohol in alcoholic beverages developmental --- October 1, 1987 Ethylbenzene cancer 100-41-4 June 11, 2004 Ethyl-tert-butyl ether male 637-92-3 December 18, 2009 Ethyl dipropylthiocarbamate developmental 759-94-4 April 27, 1999 Ethyl-4,4’-dichlorobenzilate cancer 510-15-6 January 1, 1990 Ethylene dibromide cancer 106-93-4 July 1, 1987 Ethylene dibromide developmental, male 106-93-4 May 15, 1998 Ethylene dichloride (1,2- cancer 107-06-2 October 1, 1987Dichloroethane)Ethylene glycol monoethyl ether developmental, male 110-80-5 January 1, 1989 Ethylene glycol monoethyl developmental, male 111-15-9 January 1, 1993ether acetateEthylene glycol monomethyl ether developmental, male 109-86-4 January 1, 1989 Ethylene glycol monomethyl developmental, male 110-49-6 January 1, 1993ether acetateEthyleneimine (Aziridine)cancer 151-56-4 January 1, 1988 Ethylene oxide cancer 75-21-8 July 1, 1987 Ethylene oxide female 75-21-8 February 27, 1987 Ethylene oxide developmental, male 75-21-8 August 7, 2009 Ethylene thiourea cancer 96-45-7 January 1, 1988 Ethylene thiourea developmental 96-45-7 January 1, 19932-Ethylhexanoic acid developmental 149-57-5 August 7, 2009 Ethyl methanesulfonate cancer 62-50-0 January 1, 1988 Etodolac developmental, female 41340-25-4 August 20, 1999 Etoposide cancer 33419-42-0 November 4, 2011 Etoposide developmental 33419-42-0 July 1, 1990 Etoposide in combination with cancer --- November 4, 2011 cisplatin and bleomycinEtretinate developmental 54350-48-0 July 1, 1987Fenoxaprop ethyl developmental 66441-23-4 March 26, 1999 Fenoxycarb cancer 72490-01-8 June 2, 2000 Filgrastim developmental 121181-53-1 February 27, 2001 Fluazifop butyl developmental 69806-50-4 November 6, 1998 Flunisolide developmental, female 3385-03-3 May 15, 1998 Fluorouracil developmental 51-21-8 January 1, 1989 Fluoxymesterone developmental 76-43-7 April 1, 1990 Flurazepam hydrochloride developmental 1172-18-5 October 1, 1992 Flurbiprofen developmental, female 5104-49-4 August 20, 1999 Flutamide developmental 13311-84-7 July 1, 1990 Fluticasone propionate developmental 80474-14-2 May 15, 1998 Fluvalinate developmental 69409-94-5 November 6, 1998 Folpet cancer 133-07-3 January 1, 1989 Formaldehyde (gas) cancer 50-00-0 January 1, 19882-(2-Formylhydrazino)-4- cancer 3570-75-0 January 1, 1988(5-nitro-2-furyl)thiazoleFumonisin B1cancer 116355-83-0 November 14, 2003 Furan cancer 110-00-9 October 1, 1993 Furazolidone cancer 67-45-8 January 1, 1990 Furmecyclox cancer 60568-05-0 January 1, 1990 Fusarin C cancer 79748-81-5 July 1, 1995Gallium arsenide cancer 1303-00-0 August 1, 2008 Ganciclovir cancer, developmental, 82410-32-0 August 26, 1997maleGanciclovir sodium developmental, male 107910-75-8 August 26, 1997 Gasoline engine exhaust cancer --- October 1, 1990(condensates/extracts)Gemfibrozil cancer 25812-30-0 December 22, 2000 Gemfibrozil female, male 25812-30-0 August 20, 1999 Glass wool fibers cancer --- July 1, 1990(inhalable and biopersistent)Glu-P-1 (2-Amino-6-methyldipyrido cancer 67730-11-4 January 1, 1990[1,2- a:3’,2’-d]imidazole)Glu-P-2 (2-Aminodipyrido cancer 67730-10-3 January 1, 1990[1,2-a:3’,2’-d]imidazole)Glycidaldehyde cancer 765-34-4 January 1, 1988 Glycidol cancer 556-52-5 July 1, 1990 Goserelin acetate developmental, female, 65807-02-5 August 26, 1997maleGriseofulvin cancer 126-07-8 January 1, 1990 Gyromitrin (Acetaldehyde cancer 16568-02-8 January 1, 1988methylformylhydrazone)Halazepam developmental 23092-17-3 July 1, 1990 Halobetasol propionate developmental 66852-54-8 August 20, 1999 Haloperidol developmental, female 52-86-8 January 29, 1999 Halothane developmental 151-67-7 September 1, 1996 HC Blue 1 cancer 2784-94-3 July 1, 1989Heptachlor cancer 76-44-8 July 1, 1988 Heptachlor developmental 76-44-8 August 20, 1999 Heptachlor epoxide cancer 1024-57-3 July 1, 1988 Herbal remedies containing cancer --- July 9, 2004plant species of the genusAristolochiaHexachlorobenzene cancer 118-74-1 October 1, 1987 Hexachlorobenzene developmental 118-74-1 January 1, 1989 Hexachlorobutadiene cancer 87-68-3 May 3, 2011 Hexachlorocyclohexane cancer --- October 1, 1987(technical grade)Hexachlorodibenzodioxin cancer 34465-46-8 April 1, 1988 Hexachloroethane cancer 67-72-1 July 1, 19902,4-Hexadienal (89% trans, trans cancer --- March 4, 2005isomer; 11% cis, trans isomer)Hexafluoroacetone male 684-16-2 August 1, 2008 Hexamethylphosphoramide cancer 680-31-9 January 1, 1988 Hexamethylphosphoramide male 680-31-9 October 1, 1994 Histrelin acetate developmental --- May 15, 1998 Hydramethylnon developmental, male 67485-29-4 March 5, 1999 Hydrazine cancer 302-01-2 January 1, 1988 Hydrazine sulfate cancer 10034-93-2 January 1, 1988 Hydrazobenzene cancer 122-66-7 January 1, 1988(1,2-Diphenylhydrazine)1-Hydroxyanthraquinone cancer 129-43-1 May 27, 2005 Hydroxyurea developmental 127-07-1 May 1, 1997Idarubicin hydrochloride developmental, male 57852-57-0 August 20, 1999 Ifosfamide developmental 3778-73-2 July 1, 1990Iodine-131 developmental 10043-66-0 January 1, 1989 Imazalil cancer 35554-44-0 May 20, 2011 Indeno[1,2,3-cd]pyrene cancer 193-39-5 January 1, 1988 Indium phosphide cancer 22398-80-7 February 27, 2001 IQ (2-Amino-3-methylimidazo cancer 76180-96-6 April 1, 1990[4,5-f] quinoline)Iprodione cancer 36734-19-7 May 1, 1996 Iprovalicarb cancer 140923-17-7 June 1, 2007140923-25-7Iron dextran complex cancer 9004-66-4 January 1, 1988 Isobutyl nitrite cancer 542-56-3 May 1, 1996 Isoprene cancer 78-79-5 May 1, 1996 Isopyrazam cancer 881685-58-1 July 24, 2012 Isosafrole Delisted cancer 120-58-1 October 1, 1989December 8, 2006Isotretinoin developmental 4759-48-2 July 1, 1987 Isoxaflutole cancer 141112-29-0 December 22, 2000 Kresoxim-methyl cancer 143390-89-0 February 3, 2012 Lactofen cancer 77501-63-4 January 1, 1989 Lasiocarpine cancer 303-34-4 April 1, 1988Lead developmental, female, --- February 27, 1987。
REACH ROHS CA65对比ROHS欧盟议会及欧盟委员会于2003年2月13日在其《官方公报》上发布了《废旧电子电气设备指令》（简称《WEEE指令》）和《电子电气设备中限制使用某些有害物质指令》（简称《RoHS指令》）2008年12月3日，欧盟发布了WEEE指令（2002/96/EC）和RoHS指令（2002/95/EC）的修订提案。
本次提案的目的是创造更好的法规环境，即简单、易懂、有效和可执行的法规。
RoHS指令修订，限制的六种有害物质没有变化，但四种物质——六溴环十二烷（HBCDD）、邻苯二甲酸（2-乙基己基酯）（DEHP）、邻苯二甲酸丁苄酯（BBP）和邻苯二甲酸二丁酯（DBP）——要求进行优先评估，以便考察将来是否纳入限制物质的范畴ROHS仅对于2006年7月1日起投放市场的新产品。
1. 镉（Cd <gé>）使用该物质的例子：开关、弹簧、连接器、外壳和PCB、触头、电池，含量要求小于100ppm；2. 铅（Pb）使用该物质的例子：焊料、玻璃、PVC稳定剂；含量要求小于1000ppm；3. 汞（Hg）（水银）使用该物质的例子：温控器、传感器、开关和继电器、灯泡，含量要求小于1000ppm；4. 六价铬（Cr 6+ <gè> ）使用该物质的例子：金属防腐蚀涂层，含量要求小于1000ppm；5. 多溴联苯（PBB）使用该物质的例子：阻燃剂，PCB、连接器、塑料外壳，含量要求小于1000ppm；6. 多溴联苯醚（PBDE）使用该物质的例子：阻燃剂，PCB、连接器、塑料外壳，含量要求小于1000ppm；CA65加利福尼亚州65号提案（安全饮用水和有毒物质强制法令）于1986年11月颁布实施该提案目的：保护加州公民以及保护加州饮用水资源免受以知的具有致癌、致生出缺陷或其它生殖毒性的化学物质的污染；告知加州公民有关暴露在他们所购买的物品、家里或工作场所中的化学物质或释放进入环境的化学物质的危害。
california proposition 65列表加州65号提案（California Proposition 65）是加利福尼亚州的一项法律要求，旨在提供有关在该州存在的可能导致癌症或生殖毒性的化学物质的信息。
该提案要求加州政府维护一份名为“有害物质清单”（List of Chemicals Known to the State of California to Cause Cancer or Reproductive Toxicity）的列表，其中包含已知的可能有害的化学物质。
根据加州65号提案，以下是一些常见的化学物质，可能会出现在该有害物质清单中。
请注意，这仅是一些示例，并不代表完整的清单：1. 苯（Benzene）2. 铅（Lead）3. 汞（Mercury）4. 镉（Cadmium）5. 苯并芘（Benzo[a]pyrene）6. 甲醛（Formaldehyde）7. 砷（Arsenic）8. 乙醛（Acetaldehyde）9. 可塑剂（Phthalates）10. 镍（Nickel）这些化学物质可能存在于许多不同的产品和环境中，包括食品、饮用水、药物、化妆品、家具、建筑材料等。
根据加州65号提案的规定，如果产品中含有该有害物质清单中的任何一种化学物质，制造商、分销商或零售商需要提供警告，以使消费者能够知晓潜在的危险。
请注意，有害物质清单是根据科学研究和相关机构的评估编制的，并且可能会定期更新。
如果您需要最新的有害物质清单信息，建议查阅加利福尼亚州环境保护局（California Environmental Protection Agency）或加利福尼亚州劳工部（California Department of Labor）的官方网站，以获取最新的清单和相关信息。
美国加州65标准（CP65标准）内容资料及检测测试加州第65号提案(一)加州第65号提案从颁布到现在已有20余年，一直秉持减少有毒化学物质的暴露的宗旨。
它允许加州居民通过一定的方式消除消费品和工业中的致癌物质和生殖毒性化学物质的行为。
自第65号提案制定以来，众多关于消费品中含有毒化学物质诉讼案在加州不断出现，从而引领整个美国一系列的限制标准的实施。
第65号提案，即《加州安全饮用水和有毒物执行法》，于1986 年11 月经加州居民投票，以压倒性的票数一致通过。
该提案由加州环境保护署(Cal/ EPA)辖下的环境健康危害评估机构(OEHHA) 执行。
提案规定，从事买卖的个体，其雇员人数达10个或10个以上的（另有豁免的除外），须在含已获知可致癌或生殖毒性的化学物质的产品上贴上清晰﹑合理的警告标签，以避免与人体接触，且不得将该等化学物质排放到饮用水中。
消费品警告可直接置于产品标签上，也可置于店面产品附近的显眼处（参照表1）。
表1 警告标签典型示例警告示例1 2WARNING: Thisproduct contains achemical known tothe State ofCalifornia to causecancer WARNING: This productcontains achemicalknown to the State ofCalifornia to cause birthdefects or otherreproductive harm第65号提案列出了大约800种已被加州当局确定为致癌性或生殖毒性的化学物清单。
该类化学物质清单包括大量自然产生的和人工合成的化学物质，包括用于杀虫剂﹑普通家用产品﹑食品﹑药物﹑染料或溶剂的添加剂或配料。
它们可用于制造业和建造业，也可以是化学过程的副产品，如机动车尾气。
所列化学物质包括烟草烟雾﹑金属（例如：铅﹑镉和镍）和有机化学物质（例如邻苯二甲酸盐：BBP﹑DBP﹑DEHP﹑DIDP ﹑DnHP等，及多环芳香烃：苯并芘等）。
2015-08-03 14:42:28加州65更新有害物质管控清单背景介绍加州65号提案即《1986年饮用水安全与毒性物质强制执行法》，1986年11月颁发，其宗旨是保护美国加州居民及该州的饮用水水源，使水源不含已知可能导致癌症、出生缺陷或其他生殖发育危害的物质，并在产品出现该类物质时如实通知居民。
加州65管控物质清单由OEHHA出台并每季度更新，首次出版于1987年，最新清单中物质已达900多种。
核心管控要求1、禁止引用水源污染：任何人在经营过程中不得有意排放或释放加州所知的致癌性或有生殖毒性的物质进入水源或投放到可能污染水源的土地上或土地中。
2、警示要求：某一种化学物质被列入管控清单后，制造商和经销商须在12个月内完成警告的执行，在20个月内终止化学物质排放至饮用水源头。
此日期过后，政府或个人执法者，包括代表公众利益的个人或组织，可对违反法规者提起诉讼。
3、有害物质限量要求：加州65法案管控清单本身并未对物质设定限值，产品中有害物质的管控限值，参考已有的针对此类产品的诉讼案或协议，这些文件中，可能会达成针对某类产品中某些物质的限值要求以及测试方法。
4、企业在进行加州65管控时，首先应比对已有的此类产品的诉讼案中确定的物质管控要求，然后参考此管控来调查产品中的有害物质。
CTI建议加州65本身并未规定具体管控产品类别，但是由于法案制定的目的是为了避免有害物质进入加州水源，所以，理论上来说，一切含有有害物质的产品都在其管控范围内，企业可以关注法规新增加的以及高风险的化学物质。
展开供应链调查，必要时可以进行检测，以降低产品违规风险。
2015-11-16 15:09:12加州65欲添加五氯苯酚类物质到有害物质清单背景介绍1986年11月，加利福尼亚州颁布《1986年饮用水安全与毒性物质强制执行法》，即美国加利福尼亚州关于增加对可接触的有毒化学物质关注的提案，简称“加州65提案”。
后被编纂列入加利福尼亚州健康和安全法典的25249.5 -25249.13 章。
美国加州65标准（CP65标准）内容资料及检测测试（第65号提案，即《加州安全饮用水和有毒物执行法》）加州第65号提案(一)加州第65号提案从颁布到现在已有20余年，一直秉持减少有毒化学物质的暴露的宗旨。
它允许加州居民通过一定的方式消除消费品和工业中的致癌物质和生殖毒性化学物质的行为。
自第65号提案制定以来，众多关于消费品中含有毒化学物质诉讼案在加州不断出现，从而引领整个美国一系列的限制标准的实施。
第65号提案，即《加州安全饮用水和有毒物执行法》，于1986 年11 月经加州居民投票，以压倒性的票数一致通过。
该提案由加州环境保护署(Cal/ EPA)辖下的环境健康危害评估机构(OEHHA) 执行。
提案规定，从事买卖的个体，其雇员人数达10个或10个以上的（另有豁免的除外），须在含已获知可致癌或生殖毒性的化学物质的产品上贴上清晰﹑合理的警告标签，以避免与人体接触，且不得将该等化学物质排放到饮用水中。
消费品警告可直接置于产品标签上，也可置于店面产品附近的显眼处（参照表1）。
表1 警告标签典型示例警告示例1 2WARNING: Thisproduct contains achemical known tothe StateofCalifornia to causecancer WARNING: This productcontains a chemicalknown to the State ofCalifornia to cause birthdefects or otherreproductive harm第65号提案列出了大约800种已被加州当局确定为致癌性或生殖毒性的化学物清单。
该类化学物质清单包括大量自然产生的和人工合成的化学物质，包括用于杀虫剂﹑普通家用产品﹑食品﹑药物﹑染料或溶剂的添加剂或配料。
它们可用于制造业和建造业，也可以是化学过程的副产品，如机动车尾气。
所列化学物质包括烟草烟雾﹑金属（例如：铅﹑镉和镍）和有机化学物质（例如邻苯二甲酸盐：BBP﹑DBP﹑DEHP﹑DIDP ﹑DnHP等，及多环芳香烃：苯并芘等）。
美国加州65标准（CP65标准）内容资料及检测测试（第65号提案，即《加州安全饮用水和有毒物执行法》）加州第65号提案(一)加州第65号提案从颁布到现在已有20余年，一直秉持减少有毒化学物质的暴露的宗旨。
它允许加州居民通过一定的方式消除消费品和工业中的致癌物质和生殖毒性化学物质的行为。
自第65号提案制定以来，众多关于消费品中含有毒化学物质诉讼案在加州不断出现，从而引领整个美国一系列的限制标准的实施。
第65号提案，即《加州安全饮用水和有毒物执行法》，于1986 年11 月经加州居民投票，以压倒性的票数一致通过。
该提案由加州环境保护署(Cal/ EPA)辖下的环境健康危害评估机构(OEHHA) 执行。
提案规定，从事买卖的个体，其雇员人数达10个或10个以上的（另有豁免的除外），须在含已获知可致癌或生殖毒性的化学物质的产品上贴上清晰﹑合理的警告标签，以避免与人体接触，且不得将该等化学物质排放到饮用水中。
消费品警告可直接置于产品标签上，也可置于店面产品附近的显眼处（参照表1）。
表1 警告标签典型示例警告示例1 2WARNING: Thisproduct contains achemical known tothe StateofCalifornia to causecancer WARNING: This productcontains a chemicalknown to the State ofCalifornia to cause birthdefects or otherreproductive harm第65号提案列出了大约800种已被加州当局确定为致癌性或生殖毒性的化学物清单。
该类化学物质清单包括大量自然产生的和人工合成的化学物质，包括用于杀虫剂﹑普通家用产品﹑食品﹑药物﹑染料或溶剂的添加剂或配料。
它们可用于制造业和建造业，也可以是化学过程的副产品，如机动车尾气。
所列化学物质包括烟草烟雾﹑金属（例如：铅﹑镉和镍）和有机化学物质（例如邻苯二甲酸盐：BBP﹑DBP﹑DEHP﹑DIDP ﹑DnHP等，及多环芳香烃：苯并芘等）。
STATE OF CALIFORNIAENVIRONMENTAL PROTECTION AGENCYOFFICE OF ENVIRONMENTAL HEALTH HAZARD ASSESSMENTSAFE DRINKING WATER AND TOXIC ENFORCEMENT ACT OF 1986 CHEMICALS KNOWN TO THE STATE TO CAUSE CANCER OR REPRODUCTIVE TOXICITYMay 25, 2018The Safe Drinking Water and Toxic Enforcement Act of 1986 requires that the Governor revise and republish at least once per year the list of chemicals known to the State to cause cancer or reproductive toxicity. The identification number indicated in the following list is the Chemical Abstracts Service (CAS) Registry Number. No CAS number is given when several substances are presented as a single listing. The date refers to the initial appearance of the chemical on the list. For easy reference, chemicals which are shown underlined are newly added. Chemicals or endpoints shown in strikeout were placed on the Proposition 65 list on the date noted, and have subsequently been removed.Chemical Type of Toxicity CAS No. Date ListedA-alpha-C (2-Amino-9H-pyrido Cancer 26148-68-5 January 1, 1990[2,3-b]indole)Abiraterone acetate developmental, female,male 154229-18-2 April 8, 2016Acetaldehyde Cancer 75-07-0 April 1, 1988 Acetamide cancer 60-35-5 January 1, 1990 Acetazolamide Developmental 59-66-5 August 20, 1999 Acetochlor Cancer 34256-82-1 January 1, 1989 Acetohydroxamic acid Developmental 546-88-3 April 1, 19902-Acetylaminofluorene Cancer 53-96-3 July 1, 1987 Acifluorfen sodium Cancer 62476-59-9 January 1, 1990 Acrylamide Cancer 79-06-1 January 1, 1990 Acrylamide developmental, male 79-06-1 February 25, 2011 Acrylonitrile Cancer 107-13-1 July 1, 1987 Actinomycin D Cancer 50-76-0 October 1, 1989Developmental October 1, 1992 AF-2;[2-(2-furyl)-3-(5-nitro-2-furyl)] Cancer 3688-53-7 July 1, 1987acrylamideAflatoxins Cancer --- January 1, 1988 Alachlor Cancer 15972-60-8 January 1, 1989 Alcoholic beverages, when Cancer --- July 1, 1988associated with alcohol abuseAldrin cancer 309-00-2 July 1, 1988All-trans retinoic acid developmental 302-79-4 January 1, 1989 Allyl chloride cancer 107-05-1 January 1, 1990Delisted October 29, 1999Aloe Vera, non-decolorized whole leaf extractAlprazolam cancerdevelopmental---28981-97-7December 4, 2015July 1, 1990Altretamine developmental, male 645-05-6 August 20, 1999 Amantadine hydrochloride developmental 665-66-7 February 27, 2001 Amikacin sulfate developmental 39831-55-5 July 1, 19902-Aminoanthraquinone cancer 117-79-3 October 1, 1989 p-Aminoazobenzene cancer 60-09-3 January 1, 1990 o-Aminoazotoluene cancer 97-56-3 July 1, 19874-Aminobiphenyl (4-amino- cancer 92-67-1 February 27, 1987diphenyl)1-Amino-2,4-dibromo- cancer 81-49-2 August 26, 1997anthraquinone3-Amino-9-ethylcarbazole cancer 6109-97-3 July 1, 1989hydrochloride2-Aminofluorene cancer 153-78-6 January 29, 1999 Aminoglutethimide developmental 125-84-8 July 1, 1990 Aminoglycosides developmental --- October 1, 19921-Amino-2-methylanthraquinone cancer 82-28-0 October 1, 19892-Amino-5-(5-nitro-2-furyl)-1,3,4- cancer 712-68-5 July 1, 1987thiadiazole4-Amino-2-nitrophenol cancer 119-34-6 January 29, 1999 Aminopterin developmental, female 54-62-6 July 1, 1987 Amiodarone hydrochloride developmental, female, 19774-82-4 August 26, 1997maleAmitraz developmental 33089-61-1 March 30, 1999 Amitrole cancer 61-82-5 July 1, 1987 Amoxapine developmental 14028-44-5 May 15, 1998 Amsacrine cancer 51264-14-3 August 7, 2009tert-Amyl methyl ether developmental 994-05-8 December 18, 2009 Delisted December 13, 2013Anabolic steroids female, male --- April 1, 1990 Analgesic mixtures containing cancer --- February 27, 1987phenacetinAndrostenedione cancer 63-05-8 May 3, 2011 Angiotensin converting enzyme developmental --- October 1, 1992(ACE) inhibitorsAniline cancer 62-53-3 January 1, 1990 Aniline hydrochloride cancer 142-04-1 May 15, 1998o-Anisidine cancer 90-04-0 July 1, 1987o-Anisidine hydrochloride cancer 134-29-2 July 1, 1987 Anisindione developmental 117-37-3 October 1, 1992 Anthraquinone cancer 84-65-1 September 28, 2007 Antimony oxide (Antimony trioxide) cancer 1309-64-4 October 1, 1990 Aramite cancer 140-57-8 July 1, 1987Areca nut cancer --- February 3, 2006 Aristolochic acids cancer --- July 9, 2004 Arsenic (inorganic arsenic cancer -- February 27, 1987 compounds)Arsenic (inorganic oxides) developmental --- May 1, 1997 Asbestos cancer 1332-21-4 February 27, 1987 Aspirin (NOTE: It is especially developmental, female 50-78-2 July 1, 1990important not to use aspirinduring the last three months ofpregnancy, unless specificallydirected to do so by a physicianbecause it may cause problemsin the unborn child orcomplications during delivery.)Atenolol developmental 29122-68-7 August 26, 1997 Atrazine developmental, female 1912-24-9 July 15, 2016 Auramine cancer 492-80-8 July 1, 1987 Auranofin developmental 34031-32-8 January 29, 1999 Avermectin B1 (Abamectin) developmental 71751-41-2 December 3, 2010 Azacitidine cancer 320-67-2 January 1, 1992 Azaserine cancer 115-02-6 July 1, 1987 Azathioprine cancer 446-86-6 February 27, 1987Azathioprine developmental 446-86-6 September 1, 1996 Azobenzene cancer 103-33-3 January 1, 1990Barbituratesdevelopmental ---October 1, 1992 Beclomethasone dipropionate developmental5534-09-8 May 15, 1998 Benomyldevelopmental, male 17804-35-2 July 1, 1991 Benthiavalicarb-isopropyl cancer 177406-68-7 July 1, 2008 Benz[a]anthracene cancer 56-55-3 July 1, 1987Benzene cancer71-43-2 February 27, 1987 Benzenedevelopmental, male 71-43-2 December 26, 1997 Benzidine [and its salts] cancer 92-87-5 February 27, 1987 Benzidine-based dyes cancer--- October 1, 1992 Benzodiazepines developmental ---October 1, 1992 Benzo[b]fluoranthene cancer 205-99-2 July 1, 1987 Benzo[j]fluoranthene cancer 205-82-3 July 1, 1987 Benzo[k]fluoranthene cancer 207-08-9 July 1, 1987 Benzofuran cancer 271-89-6 October 1, 1990 Benzophenone cancer 119-61-9 June 22, 2012 Benzo[a]pyrene cancer 50-32-8 July 1, 1987 Benzotrichloridecancer98-07-7 July 1, 1987 Benzphetamine hydrochloride developmental 5411-22-3 April 1, 1990 Benzyl chloride cancer 100-44-7 January 1, 1990 Benzyl violet 4Bcancer 1694-09-3 July 1, 1987 Beryllium and beryllium compounds cancer --- October 1, 1987 Betel quid with tobacco cancer --- January 1, 1990 Betel quid without tobacco cancer ---February 3, 2006 2,2-Bis(bromomethyl)-1,3- cancer 3296-90-0 May 1, 1996 propanediolBis(2-chloroethyl)ether cancer 111-44-4 April 1, 1988N,N-Bis(2-chloroethyl)-2-cancer 494-03-1 February 27, 1987 naphthylamine (Chlornapazine)Bischloroethyl nitrosourea (BCNU) cancer 154-93-8 July 1, 1987 (Carmustine)Bischloroethyl nitrosourea (BCNU) developmental 154-93-8 July 1, 1990 (Carmustine)Bis(chloromethyl)ethercancer 542-88-1 February 27, 1987 Bis(2-chloro-1-methylethyl)ether, cancer --- October 29, 1999 technical gradeBisphenol A (BPA) female80-05-7 May 11, 2015 Bisphenol A (BPA)Delisted April 19, 2013developmental80-05-7 April 11, 2013 Bitumens, extracts of steam-refined cancer --- January 1, 1990 and air refinedBracken ferncancer---January 1, 1990 Bromacil lithium salt developmental 53404-19-6 May 18, 1999 Bromacil lithium salt male 53404-19-6 January 17, 2003 Bromatecancer 15541-45-4 May 31, 2002 Bromochloroacetic acid cancer 5589-96-8 April 6, 2010 Bromodichloroacetic acid cancer 71133-14-7 July 29, 2016 Bromodichloromethane cancer 75-27-4 January 1, 1990 Bromoethane cancer 74-96-4 December 22, 2000 Bromoformcancer 75-25-2 April 1, 1991 1-Bromopropane (1-BP) 1-Bromopropane (1-BP) cancerdevelopmental, female, 106-94-5 106-94-5 August 5, 2016 December 7, 2004male2-Bromopropane (2-BP) female, male75-26-3May 31, 2005Bromoxynildevelopmental 1689-84-5 October 1, 1990 Bromoxynil octanoate developmental 1689-99-2 May 18, 1999 Butabarbital sodium developmental 143-81-7 October 1, 1992 1,3-Butadiene cancer106-99-0 April 1, 1988 1,3-Butadiene developmental, female, 106-99-0 April 16, 2004male1,4-Butanediol dimethanesulfonate cancer 55-98-1 February 27, 1987 (Busulfan)1,4-Butanediol dimethanesulfonate developmental 55-98-1 January 1, 1989 (Busulfan)Butylated hydroxyanisole cancer25013-16-5 January 1, 1990 Butyl benzyl phthalate (BBP) developmental 85-68-7 December 2, 2005 n-Butyl glycidyl ether male 2426-08-6 August 7, 2009 Delisted April 4, 2014beta-Butyrolactone cancer 3068-88-0 July 1, 1987Cacodylic acid cancer75-60-5 May 1, 1996 Cadmiumdevelopmental, male --- May 1, 1997 Cadmium and cadmium cancer --- October 1, 1987 compoundsCaffeic acid cancer 331-39-5 October 1, 1994 Captafol cancer 2425-06-1 October 1, 1988 Captancancer133-06-2 January 1, 1990 Carbamazepine developmental 298-46-4 January 29, 1999 Carbaryl cancer63-25-2 February 5, 2010 Carbaryldevelopmental, female, male 63-25-2 August 7, 2009 Carbazolecancer 86-74-8 May 1, 1996Carbon black (airborne, unbound cancer 1333-86-4 February 21, 2003 particles of respirable size)Carbon-black extracts Carbon disulfide cancerdevelopmental, female, ---75-15-0 January 1, 1990 July 1, 1989maleCarbon monoxide developmental 630-08-0 July 1, 1989 Carbon tetrachloride cancer56-23-5 October 1, 1987 Carboplatindevelopmental 41575-94-4 July 1, 1990N-Carboxymethyl-N-nitrosourea cancer 60391-92-6 January 25, 2002 Catecholcancer 120-80-9 July 15, 2003 Ceramic fibers (airborne particles cancer --- July 1, 1990 of respirable size)Certain combined chemotherapy cancer --- February 27, 1987 for lymphomasChenodiol developmental 474-25-9 April 1, 1990Chloralcancer 75-87-6 September 13, 2013 Chloral hydrate cancer 302-17-0 September 13, 2013 Chlorambucil cancer305-03-3 February 27, 1987 Chlorambucil developmental 305-03-3 January 1, 1989 ChloramphenicolDelisted January 4, 2013cancer 56-75-7 October 1, 1989 Chloramphenicol sodium succinate cancer982-57-0 September 27, 2013 Chlorcyclizine hydrochloride developmental 1620-21-9 July 1, 1987 Chlordanecancer 57-74-9 July 1, 1988 Chlordecone (Kepone) cancer143-50-0 January 1, 1988 Chlordecone (Kepone) developmental 143-50-0 January 1, 1989 Chlordiazepoxidedevelopmental 58-25-3 January 1, 1992 Chlordiazepoxide hydrochloride developmental438-41-5January 1, 1992Chlordimeform cancer 6164-98-3 January 1, 1989 Chlorendic acidcancer 115-28-6 July 1, 1989 Chlorinated paraffins (Average cancer 108171-26-2 July 1, 1989 chain length, C12; approximately 60 percent chlorine by weight)p -Chloroanilinecancer 106-47-8 October 1, 1994 p -Chloroaniline hydrochloride cancer 20265-96-7 May 15, 1998 Chlorodibromomethane cancer 124-48-1 January 1, 1990 Delisted October 29, 1999Chloroethane (Ethyl chloride) cancer 75-00-3 July 1, 1990 1-(2-Chloroethyl)-3-cyclohexyl- cancer 13010-47-4 January 1, 1988 1-nitrosourea (CCNU) (Lomustine)1-(2-Chloroethyl)-3-cyclohexyl- developmental 13010-47-4 July 1, 1990 1-nitrosourea (CCNU) Lomustine)1-(2-Chloroethyl)-3-(4-methyl- cancer 13909-09-6 October 1, 1988 cyclohexyl) -1-nitrosourea (Methyl-CCNU)Chloroform cancer67-66-3 October 1, 1987 Chloroformdevelopmental 67-66-3 August 7, 2009 Chloromethyl methyl ether cancer 107-30-2 February 27, 1987 (technical grade)3-Chloro-2-methylpropene cancer 563-47-3 July 1, 19891-Chloro-4-nitrobenzenecancer 100-00-5 October 29, 1999 4-Chloro-o -phenylenediamine cancer 95-83-0 January 1, 1988 Chloroprenecancer 126-99-8 June 2, 2000 2-Chloropropionic acid male 598-78-7 August 7, 2009 Chlorothalonilcancer 1897-45-6 January 1, 1989 p -Chloro-o -toluidinecancer 95-69-2 January 1, 1990 p-Chloro-o -toluidine, strong acid cancer --- May 15, 1998 salts of5-Chloro-o -toluidine and cancer --- October 24, 1997 its strong acid saltsChlorotrianisene cancer 569-57-3 September 1, 1996 Chlorozotocin cancer54749-90-5 January 1, 1992 Chlorpyrifos Chlorsulfurondevelopmentaldevelopmental, female, 2921-88-2 64902-72-3 December 15, 2017 May 14, 1999 Delisted June 6, 2014maleChromium (hexavalent compounds) cancer--- February 27, 1987 Chromium (hexavalent compounds) developmental, female, male ---December 19, 2008 Chrysenecancer 218-01-9 January 1, 1990 C.I. Acid Red 114 cancer 6459-94-5 July 1, 1992 C.I. Basic Red 9 cancer 569-61-9 July 1, 1989 monohydrochlorideC.I. Direct Blue 15 cancer 2429-74-5 August 26, 1997 C.I. Direct Blue 218 cancer 28407-37-6 August 26, 1997 C.I. Disperse Yellow 3 cancer 2832-40-8 February 8, 2013 C.I. Solvent Yellow 14cancer 842-07-9 May 15, 1998 Ciclosporin (Cyclosporin A; cancer 59865-13-3 January 1, 1992 Cyclosporine)79217-60-0Cidofovir cancer, developmental, 113852-37-2 January 29, 1999female, maleCinnamyl anthranilate cancer 87-29-6 July 1, 1989 Cisplatincancer 15663-27-1 October 1, 1988 Citrus Red No. 2 cancer6358-53-8 October 1, 1989 Cladribine developmental 4291-63-8 September 1, 1996 Clarithromycin developmental81103-11-9May 1, 1997Clobetasol propionate developmental, female 25122-46-7 May 15, 1998 Clofibrate cancer 637-07-0 September 1, 1996 Clomiphene citrate cancer 50-41-9 May 24, 2013 Clomiphene citrate developmental 50-41-9 April 1, 1990 Clorazepate dipotassium developmental 57109-90-7 October 1, 1992 CMNP (pyrazachlor) cancer 6814-58-0 August 25, 2015 Cobalt metal powder cancer 7440-48-4 July 1, 1992 Cobalt [II] oxide cancer 1307-96-6 July 1, 1992 Cobalt sulfate cancer 10124-43-3 May 20, 2005 Cobalt sulfate heptahydrate cancer 10026-24-1 June 2, 2000 Cocaine developmental, female 50-36-2 July 1, 1989 Coconut oil diethanolamine cancer --- June 22, 2012condensate (cocamidediethanolamine)Codeine phosphate developmental 52-28-8 May 15, 1998 Coke oven emissions cancer --- February 27, 1987 Colchicine developmental, male 64-86-8 October 1, 1992 Conjugated estrogens cancer --- February 27, 1987 Conjugated estrogens developmental --- April 1, 1990 Creosotes cancer --- October 1, 1988p-Cresidine cancer 120-71-8 January 1, 1988 Cumene cancer 98-82-8 April 6, 2010 Cupferron cancer 135-20-6 January 1, 1988 Cyanazine developmental 21725-46-2 April 1, 1990 Cycasin cancer 14901-08-7 January 1, 1988 Cycloate developmental 1134-23-2 March 19, 1999 Cyclohexanol Delisted male108-93-0November 6, 1998 January 25, 2002Cycloheximide developmental66-81-9January 1, 1989 Cyclopenta[cd]pyrene cancer 27208-37-3 April 29, 2011 Cyclophosphamide (anhydrous) cancer 50-18-0 February 27, 1987 Cyclophosphamide (anhydrous) developmental, female, 50-18-0 January 1, 1989maleCyclophosphamide (hydrated) cancer 6055-19-2 February 27, 1987 Cyclophosphamide (hydrated) developmental, female, 6055-19-2 January 1, 1989maleCyhexatin developmental 13121-70-5 January 1, 1989 Cytarabine developmental 147-94-4 January 1, 1989 Cytembena cancer 21739-91-3 May 15, 1998D&C Orange No. 17 cancer 3468-63-1 July 1, 1990D&C Red No. 8 cancer 2092-56-0 October 1, 1990D&C Red No. 9 cancer 5160-02-1 July 1, 1990D&C Red No. 19 cancer 81-88-9 July 1, 1990 Dacarbazine cancer 4342-03-4 January 1, 1988 Dacarbazine developmental 4342-03-4 January 29, 1999 Daminozide cancer 1596-84-5 January 1, 1990 Danazol developmental 17230-88-5 April 1, 1990 Dantron (Chrysazin; 1,8- cancer 117-10-2 January 1, 1992Dihydroxyanthraquinone)Daunomycin cancer 20830-81-3 January 1, 1988 Daunorubicin hydrochloride developmental 23541-50-6 July 1, 19902,4-D butyric acid developmental, male 94-82-6 June 18, 1999 DDD (Dichlorodiphenyl- cancer 72-54-8 January 1, 1989dichloroethane)DDE (Dichlorodi- cancer 72-55-9 January 1, 1989phenyldichloroethylene)DDT (Dichlorodi-cancer 50-29-3 October 1 , 1987 phenyltrichloroethane)o,p’-DDT developmental, female, 789-02-6 May 15, 1998malep,p’-DDT developmental, female, 50-29-3 May 15, 1998maleDDVP (Dichlorvos)cancer62-73-7 January 1, 1989 Demeclocycline hydrochloride developmental 64-73-3 January 1, 1992 (internal use)Des-ethyl atrazine (DEA) developmental, female 6190-65-4 July 15, 2016 Des-isopropyl atrazine (DIA) developmental, female 1007-28-9 July 15, 2016 N,N’-Diacetylbenzidine cancer 613-35-4 October 1, 1989 2,4-Diaminoanisolecancer 615-05-4 October 1, 1990 2,4-Diaminoanisole sulfate cancer39156-41-7 January 1, 1988 2,4-Diamino-6-chloro-s -triazine (DACT)developmental, female 3397-62-4 July 15, 2016 4,4’-Diaminodiphenyl ether cancer 101-80-4 January 1, 1988 (4,4’-Oxydianiline)2,4-Diaminotoluene cancer 95-80-7 January 1, 1988 Diaminotoluene (mixed)Delisted November 20, 2015 cancer---January 1, 1990 Diazepamdevelopmental 439-14-5 January 1, 1992 Diazoaminobenzene cancer136-35-6 May 20, 2005Diazoxidedevelopmental 364-98-7 February 27, 2001 Dibenz[a,h]acridine cancer 226-36-8 January 1, 1988 Dibenz[a,j]acridine cancer 224-42-0 January 1, 1988 Dibenzanthracenes cancer ---December 26, 2014 Dibenz[a,c]anthracene cancer 215-58-7 December 26, 2014 Dibenz[a,h]anthracene cancer 53-70-3 January 1, 1988 Dibenz[a,j]anthracene cancer 224-41-9 December 26, 2014 7H-Dibenzo[c,g]carbazole cancer 194-59-2 January 1, 1988 Dibenzo[a,e]pyrene cancer 192-65-4 January 1, 1988 Dibenzo[a,h]pyrene cancer 189-64-0 January 1, 1988 Dibenzo[a,i]pyrene cancer 189-55-9 January 1, 1988 Dibenzo[a,l]pyrene cancer 191-30-0 January 1, 1988 Dibromoacetic acid cancer 631-64-1 June 17, 2008 Dibromoacetonitrilecancer 3252-43-5 May 3, 2011 1,2-Dibromo-3-chloropropane cancer 96-12-8 July 1, 1987 (DBCP)1,2-Dibromo-3-chloropropane male 96-12-8 February 27, 1987 (DBCP)2,3-Dibromo-1-propanol cancer 96-13-9 October 1, 1994 Dichloroacetic acid cancer79-43-6 May 1, 1996 Dichloroacetic acid developmental, male 79-43-6 August 7, 2009 p -Dichlorobenzene cancer 106-46-7 January 1, 1989 3,3’-Dichlorobenzidine cancer 91-94-1 October 1, 1987 3,3’-Dichlorobenzidine cancer 612-83-9 May 15, 1998 dihydrochloride1,1-Dichloro-2,2-bis(p -developmental, male 72-55-9 March 30, 2010 chlorophenyl)ethylene (DDE)1,4-Dichloro-2-butenecancer 764-41-0 January 1, 1990 3,3’-Dichloro-4,4’-diaminodiphenyl cancer 28434-86-8 January 1, 1988 ether1,1-Dichloroethanecancer 75-34-3 January 1, 1990 Dichloromethane (Methylene cancer 75-09-2 April 1, 1988 chloride)Dichlorophenedevelopmental 97-23-4 April 27, 1999 1,2-Dichloropropanecancer 78-87-5 January 1, 1990 1,3-Dichloro-2-propanol (1,3-DCP) cancer 96-23-1 October 8, 2010 1,3-Dichloropropene cancer542-75-6 January 1, 1989 Dichlorphenamide developmental 120-97-8 February 27, 2001 Diclofop-methyl cancer51338-27-3 April 6, 2010 Diclofop methyl developmental 51338-27-3 March 5, 1999 Dicumarol developmental 66-76-2 October 1, 1992 Dieldrincancer 60-57-1 July 1, 1988 Dienestrol Delisted January 4, 2013 cancer 84-17-3 January 1, 1990 Diepoxybutanecancer 1464-53-5 January 1, 1988 Diesel engine exhaust cancer ---October 1, 1990 Diethanolaminecancer 111-42-2 June 22, 2012 Di(2-ethylhexyl)phthalate (DEHP) cancer117-81-7 January 1, 1988 Di(2-ethylhexyl)phthalate (DEHP) developmental, male 117-81-7 October 24, 2003 1,2-Diethylhydrazine cancer 1615-80-1 January 1, 1988 Diethylstilbestrol (DES) cancer56-53-1 February 27, 1987 Diethylstilbestrol (DES) developmental 56-53-1 July 1, 1987 Diethyl sulfate cancer64-67-5 January 1, 1988 Diflunisaldevelopmental, female 22494-42-4 January 29, 1999 Diglycidyl ethermale 2238-07-5 August 7, 2009 Delisted April 4, 2014Diglycidyl resorcinol ether (DGRE) cancer101-90-6 July 1, 1989Di-n -hexyl phthalate (DnHP) female, male84-75-3 December 2, 2005 Di-n -butyl phthalate (DBP)Dihydroergotamine mesylate developmental, female, maledevelopmental 84-74-26190-39-2 December 2, 2005May 1, 1997 Dihydrosafrolecancer94-58-6 January 1, 1988 Di-isodecyl phthalate (DIDP) developmental 68515-49-1/ April 20, 200726761-40-0Diisononyl phthalate (DINP) cancer ---December 20, 2013 Diisopropyl sulfatecancer2973-10-6 April 1, 1993Diltiazem hydrochloride developmental 33286-22-5 February 27, 2001 3,3’-Dimethoxybenzidine cancer 119-90-4 January 1, 1988 (o -Dianisidine)3,3’-Dimethoxybenzidine cancer 20325-40-0 October 1, 1990 dihydrochloride3,3’-Dimethoxybenzidine-based cancer --- June 11, 2004 dyes metabolized to 3,3’- dimethoxybenzidineN,N-Dimethylacetamided evelopmental , male 127-19-5 May 21, 2010 4-Dimethylaminoazobenzene cancer 60-11-7 January 1, 1988 trans -2-[(Dimethylamino)methyl- cancer 55738-54-0 January 1, 1988 imino]-5-[2-(5-nitro-2-furyl)vinyl]- 1,3,4-oxadiazole7,12-Dimethylbenz(a)anthracene cancer 57-97-6 January 1, 1990 3,3’-Dimethylbenzidine cancer 119-93-7 January 1, 1988 (ortho-Tolidine)3,3’-Dimethylbenzidine-based cancer --- June 11, 2004 dyes metabolized to 3,3’- dimethylbenzidine3,3’-Dimethylbenzidine cancer 612-82-8 April 1, 1992 dihydrochlorideDimethylcarbamoyl chloride cancer 79-44-7 January 1, 1988 N,N-Dimethylformamide1,1-Dimethylhydrazine (UDMH) cancer cancer 68-12-2 57-14-7 October 27, 2017 October 1, 1989 1,2-Dimethylhydrazine cancer 540-73-8 January 1, 19882,6-Dimethyl-N-nitrosomorpholine (DMNM)cancer1456-28-6 February 8, 2013 Dimethyl sulfatecancer 77-78-1 January 1, 1988 N,N -Dimethyl-p -toluidine cancer 99-97-8 May 2, 2014 Dimethylvinylchloride m -Dinitrobenzene cancer male 513-37-1 99-65-0 July 1, 1989 July 1, 1990 o -Dinitrobenzene male 528-29-0 July 1, 1990 p -Dinitrobenzenemale 100-25-4 July 1, 1990 3,7-Dinitrofluoranthene cancer 105735-71-5 August 26, 1997 3,9-Dinitrofluoranthene cancer 22506-53-2 August 26, 1997 1,3-Dinitropyrene cancer 75321-20-9 November 2, 2012 1,6-Dinitropyrene cancer 42397-64-8 October 1, 1990 1,8-Dinitropyrenecancer42397-65-9 October 1, 1990 Dinitrotoluene (technical grade) 2,4-Dinitrotoluene female, male cancer ---121-14-2 August 20, 1999 July 1, 1988 2,4-Dinitrotoluene male 121-14-2 August 20, 1999 2,6-Dinitrotoluene cancer 606-20-2 July 1, 1995 2,6-Dinitrotoluenemale 606-20-2 August 20, 1999 Dinitrotoluene mixture, 2,4-/2,6- cancer---May 1, 1996 Dinocap developmental39300-45-3 April 1, 1990 Dinosebdevelopmental, male 88-85-7 January 1, 1989 Di-n -propyl isocinchomeronate cancer 136-45-8 May 1, 1996 (MGK Repellent 326)1,4-Dioxanecancer 123-91-1 January 1, 1988 Diphenylhydantoin (Phenytoin) cancer57-41-0 January 1, 1988 Diphenylhydantoin (Phenytoin) developmental 57-41-0 July 1, 1987 Diphenylhydantoin (Phenytoin), cancer 630-93-3 January 1, 1988 sodium saltDirect Black 38 (technical grade) cancer 1937-37-7 January 1, 1988 Direct Blue 6 (technical grade) cancer 2602-46-2 January 1, 1988 Direct Brown 95 (technical grade) cancer16071-86-6 October 1, 1988 Disodium cyanodithioimido- developmental 138-93-2 March 30, 1999 carbonateDisperse Blue 1 cancer 2475-45-8 October 1, 1990 Diuroncancer 330-54-1 May 31, 2002 Doxorubicin hydrochloride cancer 25316-40-9 July 1, 1987 (Adriamycin)Doxorubicin hydrochloride developmental, male 25316-40-9 January 29, 1999 (Adriamycin)Doxycycline (internal use)developmental 564-25-0 July 1, 1990 Doxycycline calcium (internal use) developmental 94088-85-4 January 1, 1992 Doxycycline hyclate (internal use) developmental 24390-14-5 October 1, 1991 Doxycycline monohydrate developmental 17086-28-1 October 1, 1991 (internal use)2,4-DP (dichloroprop)developmental 120-36-5 April 27, 1999 Delisted January 25, 2002Emissions from combustion of coal cancer --- August 7, 2013 Emissions from high-temperature cancer --- January 3, 2014 unrefined rapeseed oilEndrindevelopmental 72-20-8 May 15, 1998 Environmental tobacco smoke developmental --- June 9, 2006 (ETS)Epichlorohydrin cancer 106-89-8 October 1, 1987 Epichlorohydrin male 106-89-8 September 1, 1996 Epoxiconazole cancer135319-73-2April 15, 2011Ergotamine tartrate developmental 379-79-3 April 1, 1990 Erionite cancer 12510-42-8/ October 1, 198866733-21-9Estradiol 17B cancer 50-28-2 January 1, 1988 Estragole cancer 140-67-0 October 29, 1999 Estrogens, steroidal cancer --- August 19, 2005 Estrogen-progestogen (combined) cancer --- November 4, 2011 used as menopausal therapyEstrone cancer 53-16-7 January 1, 1988 Estropipate cancer, developmental 7280-37-7 August 26, 1997 Ethanol in alcoholic beverages cancer --- April 29, 2011 Ethinylestradiol cancer 57-63-6 January 1, 1988 Ethionamide developmental 536-33-4 August 26, 1997 Ethoprop cancer 13194-48-4 February 27, 2001 Ethyl acrylate cancer 140-88-5 July 1, 1989Ethyl alcohol in alcoholic beverages developmental --- October 1, 1987 Ethylbenzene cancer 100-41-4 June 11, 2004 Ethyl-tert-butyl ether male637-92-3December 18, 2009 Delisted December 13, 2013Ethyl dipropylthiocarbamate developmental 759-94-4 April 27, 1999 Ethyl-4,4’-dichlorobenzilate cancer 510-15-6 January 1, 1990 Ethylene dibromide cancer 106-93-4 July 1, 1987 Ethylene dibromide developmental, male 106-93-4 May 15, 1998 Ethylene dichloride (1,2- cancer 107-06-2 October 1, 1987Dichloroethane)Ethylene glycol (ingested) developmental 107-21-1 June 19, 2015 Ethylene glycol monoethyl ether developmental, male 110-80-5 January 1, 1989 Ethylene glycol monoethyl developmental, male 111-15-9 January 1, 1993ether acetateEthylene glycol monomethyl ether developmental, male109-86-4January 1, 1989 Ethylene glycol monomethyl developmental, male 110-49-6 January 1, 1993ether acetateEthyleneimine (Aziridine) cancer 151-56-4 January 1, 1988 Ethylene oxide cancer 75-21-8 July 1, 1987 Ethylene oxide female 75-21-8 February 27, 1987 Ethylene oxide developmental, male 75-21-8 August 7, 2009 Ethylene thiourea cancer 96-45-7 January 1, 1988 Ethylene thiourea developmental 96-45-7 January 1, 19932-Ethylhexanoic acid developmental149-57-5August 7, 2009 Delisted December 13, 2013Ethyl methanesulfonate cancer 62-50-0 January 1, 1988 Etodolac developmental, female 41340-25-4 August 20, 1999 Etoposide cancer 33419-42-0 November 4, 2011 Etoposide developmental 33419-42-0 July 1, 1990 Etoposide in combination with cancer --- November 4, 2011 cisplatin and bleomycinEtretinate developmental 54350-48-0 July 1, 1987Fenoxaprop ethyl developmental66441-23-4March 26, 1999 Fenoxycarb cancer 72490-01-8 June 2, 2000 Filgrastim developmental 121181-53-1 February 27, 2001 Fluazifop butyl developmental 69806-50-4 November 6, 1998 Flunisolide developmental, female 3385-03-3 May 15, 1998 Fluorouracil developmental 51-21-8 January 1, 1989 Fluoxymesterone developmental 76-43-7 April 1, 1990 Flurazepam hydrochloride developmental 1172-18-5 October 1, 1992Flurbiprofen developmental, female 5104-49-4 August 20, 1999 Flutamidedevelopmental 13311-84-7 July 1, 1990 Fluticasone propionate developmental 80474-14-2 May 15, 1998Fluvalinate developmental 69409-94-5 November 6, 1998 Folpetcancer 133-07-3 January 1, 1989 Formaldehyde (gas)cancer 50-00-0 January 1, 1988 2-(2-Formylhydrazino)-4- cancer 3570-75-0 January 1, 1988 (5-nitro-2-furyl)thiazoleFumonisin B 1 cancer 116355-83-0 November 14, 2003 Furancancer 110-00-9 October 1, 1993 Furazolidone cancer 67-45-8 January 1, 1990 Furfuryl alcohol Furmecyclox cancer cancer 98-00-0 60568-05-0 September 30, 2016 January 1, 1990 Fusarin C cancer 79748-81-5 July 1, 1995Gallium arsenide cancer1303-00-0 August 1, 2008 Ganciclovir cancer, developmental, 82410-32-0 August 26, 1997maleGanciclovir sodiumdevelopmental, male 107910-75-8 August 26, 1997 Gasoline engine exhaust cancer --- October 1, 1990 (condensates/extracts)Gemfibrozil cancer25812-30-0 December 22, 2000 Gemfibrozilfemale, male 25812-30-0 August 20, 1999 Glass wool fibers(inhalable and biopersistent)Glu-P-1 (2-Amino-6-methyldipyrido cancercancer ---67730-11-4 July 1, 1990January 1, 1990 [1,2- a:3’,2’-d]imidazole)Glu-P-2 (2-Aminodipyrido cancer 67730-10-3 January 1, 1990 [1,2-a:3’,2’-d]imidazole)Glycidaldehyde cancer 765-34-4 January 1, 1988 Glycidol cancer 556-52-5 July 1, 1990 GlyphosateGoldenseal root powder cancer cancer1071-83-6 ---July 7, 2017December 4, 2015 Goserelin acetate developmental, female, 65807-02-5 August 26, 1997maleGriseofulvincancer 126-07-8 January 1, 1990 Gyromitrin (Acetaldehyde cancer 16568-02-8 January 1, 1988 methylformylhydrazone)Halazepamdevelopmental 23092-17-3 July 1, 1990 Halobetasol propionate developmental66852-54-8 August 20, 1999 Haloperidol developmental, female 52-86-8 January 29, 1999 Halothane developmental 151-67-7 September 1, 1996 HC Blue 1 cancer 2784-94-3 July 1, 1989 Heptachlor cancer76-44-8 July 1, 1988 Heptachlordevelopmental 76-44-8 August 20, 1999 Heptachlor epoxidecancer 1024-57-3 July 1, 1988 Herbal remedies containing cancer --- July 9, 2004 plant species of the genus AristolochiaHexachlorobenzene cancer118-74-1 October 1, 1987 Hexachlorobenzene developmental 118-74-1 January 1, 1989 Hexachlorobutadiene cancer 87-68-3 May 3, 2011 Hexachlorocyclohexane cancer --- October 1, 1987 (technical grade)。
