PF-06282999_LCMS_22815_MedChemExpress

=====================================================================Acq. Operator : Li Shan(LCMS-02) Seq. Line : 44Acq. Instrument : HY-LCMS-02 Location : Vial 63Injection Date : 2/4/2015 3:42:58 PM Inj : 1Inj Volume : 3.000 µlAcq. Method : D:\AGLIENT 1260\DATA\20150204\20150204 2015-02-04 12-03-03\100-1000MS+3MIN( 0.02%FA).MLast changed : 2/4/2015 12:03:03 PM by Li Shan(LCMS-02)Analysis Method : D:\AGLIENT 1260\DATA\20150203\20150203 2015-02-03 10-26-16\100-1000MS+3MIN( 0.02%FA).M (Sequence Method)Last changed : 2/4/2015 4:15:52 PM by Li Shan(LCMS-02) (modified after loading)Method Info : Postive,MS:100-1000,Column ID:A-RP-102,40℃Catalog No : HY-10528 Batch#07184 A-RP-32Additional Info : Peak(s) manually integratedmin0.511.522.53mAU2004006008001000 DAD1 B, Sig=214,4 Ref=off (D:\AGLIENT...0\DATA\20150204\20150204 2015-02-04 12-03-03\CPK2015-204-07184.D)1.7581.8672.007===================================================================== Area Percent Report =====================================================================Sorted By : Signal Multiplier : 1.0000Dilution : 1.0000Do not use Multiplier & Dilution Factor with ISTDsSignal 1: DAD1 B, Sig=214,4 Ref=offPeak RetTime Type Width Area Height Area # [min] [min] [mAU*s] [mAU] %----|-------|----|-------|----------|----------|--------| 1 1.758 MM 0.0468 3044.39502 1083.92749 99.8707 2 1.867 MM 0.0451 2.40411 8.88902e-1 0.0789 3 2.007 MM 0.0358 1.53615 7.15266e-1 0.0504Totals : 3048.33527 1085.53166===================================================================== *** End of Report ***=====================================================================Acq. Operator : Li Shan(LCMS-02) Seq. Line : 44Acq. Instrument : HY-LCMS-02 Location : Vial 63Injection Date : 2/4/2015 3:42:58 PM Inj : 1Inj Volume : 3.000 µlAcq. Method : D:\AGLIENT 1260\DATA\20150204\20150204 2015-02-04 12-03-03\100-1000MS+3MIN( 0.02%FA).MLast changed : 2/4/2015 12:03:03 PM by Li Shan(LCMS-02)Analysis Method : D:\AGLIENT 1260\DATA\20150203\20150203 2015-02-03 10-26-16\100-1000MS+3MIN( 0.02%FA).M (Sequence Method)Last changed : 2/4/2015 4:17:05 PM by Li Shan(LCMS-02) (modified after loading)Method Info : Postive,MS:100-1000,Column ID:A-RP-102,40℃Catalog No : HY-10528 Batch#07184 A-RP-32Additional Info : Peak(s) manually integratedmin0.511.522.53250005000075000100000125000150000175000200000225000 MSD1 TIC, MS File (D:\AGLIENT 1260\DATA\20150204\20150204 2015-02-04 12-03-03\CPK2015-204-07184.D) ES-API, Pos, Sc1.757MS Signal: MSD1 TIC, MS File, ES-API, Pos, Scan, Frag: 50 Spectra averaged over upper half of peaks. Noise Cutoff: 1000 counts.Reportable Ion Abundance: > 10%.Retention Mol. Weight Time (MS) MS Area or Ion1.757 909177 836.15 I 835.20 I 408.10 I 407.10 Im/z10020030040050060070080020406080100*MSD1 SPC, time=1.744:1.780 of D:\AGLIENT 1260\DATA\20150204\20150204 2015-02-04 12-03-03\CPK2015-204-07184.D ES-API Max: 103061836.2 408.1835.2407.1*** End of Report ***。

=====================================================================Acq. Operator : Yang Qian(LCMS-02) Seq. Line : 46Acq. Instrument : HY-LCMS-02 Location : P2-F-06Injection Date : 12/14/2015 12:14:04 PM Inj : 1 Inj Volume : 3.000 µlAcq. Method : D:\AGLIENT 1260\DATA\20151214\20151214 2015-12-14 08-45-47\100-1000MS+3MIN- 1.5_(0.02%FA)-BD.MLast changed : 12/14/2015 8:45:47 AM by Yang Qian(LCMS-02)Analysis Method : D:\AGLIENT 1260\METHOD\1000-2000MS+3MIN_1.5(0.02%FA).MLast changed : 12/14/2015 12:56:06 PM by Yang Qian(LCMS-02) (modified after loading)Method Info : Postive,MS:1000-2000,Column ID:A-RP-132,40℃

Catalog No : HY-10971 Batch#18919 A-RP-134

Additional Info : Peak(s) manually integrated

min0.511.522.53

mAU0500100015002000

DAD1 B, Sig=214,4 Ref=off (D:\AGLIENT 1260\DATA\20151214\20151214 2015-12-14 08-45-47\BIZ2015-D12-WJ3.D)

=====================================================================Acq. Operator : Yang Qian(LCMS-02) Seq. Line : 44Acq. Instrument : HY-LCMS-02 Location : P2-E-07Injection Date : 11/12/2015 1:20:47 PM Inj : 1 Inj Volume : 3.000 µl Acq. Method : D:\AGLIENT 1260\DATA\20151112\20151112 2015-11-12 08-47-27\100-1000MS+3MIN- 1.5_(0.02%FA)-BD.M Last changed : 11/12/2015 8:47:27 AM by Yang Qian(LCMS-02)Analysis Method : D:\AGLIENT 1260\METHOD\100-1000MS+3MIN-1.5_(0.02%FA)-BD.M Last changed : 11/12/2015 1:36:22 PM by Yang Qian(LCMS-02) (modified after loading)Method Info : Postive,MS:100-1000,Column ID:A-RP-132,40℃ Catalog No : HY-13740 Batch#18550 A-RP-134 Additional Info : Peak(s) manually integrated min0.51 1.52 2.53mAU 025050075010001250150017502000 DAD1 B, Sig=214,4 Ref=off (D:\AGLIENT 1260\DATA\20151112\20151112 2015-11-12 08-47-27\BIZ2015-N12-WJ2.D)1.491 1.567 1.858 ===================================================================== Area Percent Report ===================================================================== Sorted By : Signal Multiplier : 1.0000Dilution : 1.0000Do not use Multiplier & Dilution Factor with ISTDs Signal 1: DAD1 B, Sig=214,4 Ref=off Peak RetTime Type Width Area Height Area # [min] [min] [mAU*s] [mAU] %----|-------|----|-------|----------|----------|--------| 1 1.491 MF 0.0446 4.47831 1.67258 0.0524 2 1.567 FM 0.0664 8541.19336 2144.25610 99.8495 3 1.858 MM 0.0575 8.394852.43356 0.0981 Totals : 8554.06652 2148.36224 ===================================================================== *** End of Report ***=====================================================================Acq. Operator : Yang Qian(LCMS-02) Seq. Line : 44Acq. Instrument : HY-LCMS-02 Location : P2-E-07Injection Date : 11/12/2015 1:20:47 PM Inj : 1 Inj Volume : 3.000 µl Acq. Method : D:\AGLIENT 1260\DATA\20151112\20151112 2015-11-12 08-47-27\100-1000MS+3MIN- 1.5_(0.02%FA)-BD.M Last changed : 11/12/2015 8:47:27 AM by Yang Qian(LCMS-02)Analysis Method : D:\AGLIENT 1260\METHOD\100-1000MS+3MIN-1.5_(0.02%FA)-BD.M Last changed : 11/12/2015 1:38:04 PM by Yang Qian(LCMS-02) (modified after loading)Method Info : Postive,MS:100-1000,Column ID:A-RP-132,40℃ Catalog No : HY-13740 Batch#18550 A-RP-134 Additional Info : Peak(s) manually integrated min0.51 1.52 2.53020000040000060000080000010000001200000 MSD1 TIC, MS File (D:\AGLIENT 1260\DATA\20151112\20151112 2015-11-12 08-47-27\BIZ2015-N12-WJ2.D) ES-API, Pos, Scan1.581MS Signal: MSD1 TIC, MS File, ES-API, Pos, Scan, Frag: 50 Spectra averaged over upper half of peaks. Noise Cutoff: 1000 counts. Reportable Ion Abundance: > 10%. Retention Mol. Weight Time (MS) MS Area or Ion 1.581 8178084 316.20 I 315.20 Im/z 100200300400500600700800020406080100*MSD1 SPC, time=1.544:1.635 of D:\AGLIENT 1260\DATA\20151112\20151112 2015-11-12 08-47-27\BIZ2015-N12-WJ2.D ES-API, Max: 800352316.2 315.2 *** End of Report ***。

=====================================================================Acq. Operator : Li Shan(LCMS-02) Seq. Line : 84Acq. Instrument : HY-LCMS-02 Location : P2-C-05Injection Date : 6/5/2015 4:13:47 PM Inj : 1 Inj Volume : 3.000 µl Acq. Method : D:\AGLIENT 1260\DATA\20150605\20150605 2015-06-05 09-21-31\100-1000MS+3MIN- 1.5_(0.02%FA).M Last changed : 6/5/2015 9:21:31 AM by Li Shan(LCMS-02)Analysis Method : D:\AGLIENT 1260\METHOD\5-80A(RP-HPLC).M Last changed : 6/5/2015 4:55:55 PM by Li Shan(LCMS-02) (modified after loading)Method Info : 10-80A,16MIN Catalog No : HY-12588 Batch#16482 A-RP-132 Additional Info : Peak(s) manually integrated min0.51 1.52 2.53mAU200400600800DAD1 B, Sig=214,4 Ref=off (D:\AGLIENT...60\DATA\20150605\20150605 2015-06-05 09-21-31\BIZ2015-605-DJL9.D)0.394 0.498 2.228 ===================================================================== Area Percent Report ===================================================================== Sorted By : Signal Multiplier : 1.0000Dilution : 1.0000Do not use Multiplier & Dilution Factor with ISTDs Signal 1: DAD1 B, Sig=214,4 Ref=off Peak RetTime Type Width Area Height Area # [min] [min] [mAU*s] [mAU] %----|-------|----|-------|----------|----------|--------| 1 0.394 MM 0.0425 2829.96558 1108.66125 99.2783 2 0.498 MM 0.0339 5.77030 2.83656 0.2024 3 2.228 MM 0.0639 14.80108 3.85942 0.5192 Totals : 2850.53696 1115.35724 ===================================================================== *** End of Report ***=====================================================================Acq. Operator : Li Shan(LCMS-02) Seq. Line : 84Acq. Instrument : HY-LCMS-02 Location : P2-C-05Injection Date : 6/5/2015 4:13:47 PM Inj : 1 Inj Volume : 3.000 µl Acq. Method : D:\AGLIENT 1260\DATA\20150605\20150605 2015-06-05 09-21-31\100-1000MS+3MIN- 1.5_(0.02%FA).M Last changed : 6/5/2015 9:21:31 AM by Li Shan(LCMS-02)Analysis Method : D:\AGLIENT 1260\METHOD\5-80A(RP-HPLC).M Last changed : 6/5/2015 4:56:55 PM by Li Shan(LCMS-02) (modified after loading)Method Info : 10-80A,16MIN Catalog No : HY-12588 Batch#16482 A-RP-132 Additional Info : Peak(s) manually integrated min0.51 1.52 2.530100000200000300000400000500000MSD1 TIC, MS File (D:\AGLIENT 1260\DATA\20150605\20150605 2015-06-05 09-21-31\BIZ2015-605-DJL9.D) ES-API, Pos, Sca0.392MS Signal: MSD1 TIC, MS File, ES-API, Pos, Scan, Frag: 50 Spectra averaged over upper half of peaks. Noise Cutoff: 1000 counts. Reportable Ion Abundance: > 10%. Retention Mol. Weight Time (MS) MS Area or Ion 0.392 2110102 250.10 I 249.10 Im/z 100200300400500600020406080100*MSD1 SPC, time=0.377:0.413 of D:\AGLIENT 1260\DATA\20150605\20150605 2015-06-05 09-21-31\BIZ2015-605-DJL9.D ES-API,Max: 377429251.1 249.1 *** End of Report ***。