• 1990‘s中期,芝加哥大学报道住院病人MRSA增加25倍 • 1999年报道4例儿童死于致死性社区获得性MRSA(CA-
MRSA)感染,这些儿童并无MRSA易感因素
CA-MRSA定义
美国CDC将CA-MRSA 定义:
– 门诊或住院后48小时内分离到MRSA菌株 – 一年内无养老院、护理院或医院住院史, – 无透析或手术史、无永久性经皮留置体内的
Prevalence of MRSA in China
798 isolates, 2005, 12 Cities, China
100 80.3
80
CHINET 2007, China MRSA 58% (1963/3384)
60
55.5 50 47.1 45.2
50.5
40
35.5 37
20
0 Shanghai Beijing Shenyang Hangzhou Guangzhou Wuhan
Emerg Infect Dis. (2007). 13 (12): 1840–6. JAMA, 2007, Oct, 298: 1报道从静脉吸毒者或经常接触护理机构的 高危人群种分离出MRSA
• 80年代后期,首次报道从经常接触护理所的儿童中分离到 MRSA
infections that required treatment – Many patients were children who required
hospitalization
Washington Post. Retrieved on 2007-10-19
Community-acquired MRSA in Asia
• annual deaths increased from 11,000 to more thanM1R7S,0A00deaat thes>saAmIDe Stime